-
1
-
-
0023614553
-
Induction of sister chromatid exchanges at common fragile sites
-
Glover, T.W. and Stein, C.K. (1987) Induction of sister chromatid exchanges at common fragile sites. Am. J. Hum. Genet., 41, 882-890.
-
(1987)
Am. J. Hum. Genet.
, vol.41
, pp. 882-890
-
-
Glover, T.W.1
Stein, C.K.2
-
2
-
-
0023789150
-
Chromosome breakage and recombination at fragile sites
-
Glover, T.W. and Stein, C.K. (1988) Chromosome breakage and recombination at fragile sites. Am. J. Hum. Genet., 43, 265-273.
-
(1988)
Am. J. Hum. Genet.
, vol.43
, pp. 265-273
-
-
Glover, T.W.1
Stein, C.K.2
-
3
-
-
0026017993
-
Preferential integration of marker DNA into the chromosomal fragile site at 3p14: An approach to cloning fragile sites
-
Rassool, F.V., McKeithan, T.W., Neilly, M.E., van Melle, E., Espinosa, R., III and Le Beau, M.M. (1991) Preferential integration of marker DNA into the chromosomal fragile site at 3p14: an approach to cloning fragile sites. Proc. Natl Acad. Sci. USA, 88, 6657-6661.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 6657-6661
-
-
Rassool, F.V.1
McKeithan, T.W.2
Neilly, M.E.3
van Melle, E.4
Espinosa III, R.5
Le Beau, M.M.6
-
4
-
-
0034326237
-
Human papillomavirus type 16 integrations in cervical tumors frequently occur in common fragile sites
-
Thorland, E.C., Myers, S.L., Persing, D.H., Sarkar, G., McGovern, R.M., Gostout, B.S. and Smith, D.I. (2000) Human papillomavirus type 16 integrations in cervical tumors frequently occur in common fragile sites. Cancer Res., 60, 5916-5921.
-
(2000)
Cancer Res.
, vol.60
, pp. 5916-5921
-
-
Thorland, E.C.1
Myers, S.L.2
Persing, D.H.3
Sarkar, G.4
McGovern, R.M.5
Gostout, B.S.6
Smith, D.I.7
-
5
-
-
0022620716
-
Chromosomal fragile sites and cancer-specific rearrangements
-
Le Beau, M.M. (1986) Chromosomal fragile sites and cancer-specific rearrangements. Blood, 67, 849-858.
-
(1986)
Blood
, vol.67
, pp. 849-858
-
-
Le Beau, M.M.1
-
6
-
-
0023922439
-
Fragile sites, cancer chromosome breakpoints, and oncogenes are all cluster in light G bands
-
Hecht, F. (1988) Fragile sites, cancer chromosome breakpoints, and oncogenes are all cluster in light G bands. Cancer Genet. Cytogenet., 31, 17-24.
-
(1988)
Cancer Genet. Cytogenet.
, vol.31
, pp. 17-24
-
-
Hecht, F.1
-
7
-
-
0029083316
-
Enhanced expression of common fragile sites with occupational exposure to pesticides
-
Sbrana, I. and Musio, A. (1995) Enhanced expression of common fragile sites with occupational exposure to pesticides. Cancer Genet. Cytogenet., 82, 123-127.
-
(1995)
Cancer Genet. Cytogenet.
, vol.82
, pp. 123-127
-
-
Sbrana, I.1
Musio, A.2
-
8
-
-
0031005091
-
Aphidicolin-sensitive specific common fragile sites: A biomarker of exposure to pesticides
-
Musio, A. and Sbrana, I. (1997) Aphidicolin-sensitive specific common fragile sites: a biomarker of exposure to pesticides. Environ. Mol. Mutagen., 29, 250-255.
-
(1997)
Environ. Mol. Mutagen
, vol.29
, pp. 250-255
-
-
Musio, A.1
Sbrana, I.2
-
9
-
-
0035753424
-
Fra3b and other common fragile sites: The weakest links
-
Huebner, K. and Croce, C.M. (2001) Fra3b and other common fragile sites: the weakest links. Nat. Rev. Cancer, 1, 214-221.
-
(2001)
Nat. Rev. Cancer
, vol.1
, pp. 214-221
-
-
Huebner, K.1
Croce, C.M.2
-
10
-
-
0035853128
-
FHIT gene therapy prevents tumor development in Fhit-deficient mice
-
Dumon, K.R., Ishii, H., Fong, L.Y.Y., Zanesi, N., Fidanza, V., Mancini, R., Vecchione, A., Baffa, R., Trapasso, F., During, M.J. et al. (2001) FHIT gene therapy prevents tumor development in Fhit-deficient mice. Proc. Natl Acad. Sci. USA, 98, 3346-3351.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 3346-3351
-
-
Dumon, K.R.1
Ishii, H.2
Fong, L.Y.Y.3
Zanesi, N.4
Fidanza, V.5
Mancini, R.6
Vecchione, A.7
Baffa, R.8
Trapasso, F.9
During, M.J.10
-
11
-
-
0034654513
-
A 700-Kb physical map of a region of 16q23.2 homozygously deleted in multiple cancers and spanning the common fragile site FRA16D
-
Paige, A.J., Taylor, K.J., Stewart, A., Sgouros, J.G., Gabra, H., Sellar, G.C., Smyth, J.F., Porteous, D.J. and Watson, J.E.V. (2000) A 700-Kb physical map of a region of 16q23.2 homozygously deleted in multiple cancers and spanning the common fragile site FRA16D. Cancer Res., 60, 1690-1697.
-
(2000)
Cancer Res.
, vol.60
, pp. 1690-1697
-
-
Paige, A.J.1
Taylor, K.J.2
Stewart, A.3
Sgouros, J.G.4
Gabra, H.5
Sellar, G.C.6
Smyth, J.F.7
Porteous, D.J.8
Watson, J.E.V.9
-
12
-
-
0021278143
-
DNA polymerase α inhibition by aphidicolin induces gaps and breaks at common fragile sites in human chromosomes
-
Glover, T.W., Berger, C., Coyle, J. and Echo, B. (1984) DNA polymerase α inhibition by aphidicolin induces gaps and breaks at common fragile sites in human chromosomes. Hum. Genet., 67, 136-142.
-
(1984)
Hum. Genet.
, vol.67
, pp. 136-142
-
-
Glover, T.W.1
Berger, C.2
Coyle, J.3
Echo, B.4
-
13
-
-
0029090957
-
DNA polymerase alpha, a component of replication initiation complex, is essential for the checkpoint coupling S phase to mitosis in fission yeast
-
D'Urso, G., Grallert, B. and Nurse, P. (1995) DNA polymerase alpha, a component of replication initiation complex, is essential for the checkpoint coupling S phase to mitosis in fission yeast. J. Cell Sci., 108, 3109-3118.
-
(1995)
J. Cell Sci.
, vol.108
, pp. 3109-3118
-
-
D'Urso, G.1
Grallert, B.2
Nurse, P.3
-
14
-
-
0028979332
-
DNA polymerase epsilon links the DNA replication machinery to the S phase checkpoint
-
Navas, T.A., Zhou, Z. and Elledge, S.J. (1995) DNA polymerase epsilon links the DNA replication machinery to the S phase checkpoint. Cell, 80, 29-39.
-
(1995)
Cell
, vol.80
, pp. 29-39
-
-
Navas, T.A.1
Zhou, Z.2
Elledge, S.J.3
-
15
-
-
0031899979
-
Common fragile sites on human chromosomes represent transcriptionally active regions: Evidence from campthothecin
-
Sbrana, I., Zavattari, P., Barale, R. and Musio, A. (1998) Common fragile sites on human chromosomes represent transcriptionally active regions: evidence from campthothecin. Hum. Genet., 102 409-414.
-
(1998)
Hum. Genet.
, vol.102
, pp. 409-414
-
-
Sbrana, I.1
Zavattari, P.2
Barale, R.3
Musio, A.4
-
16
-
-
0037069944
-
Evidence that instability within FRA3B extends four megabases
-
Becker, N.A., Thorland, E.C., Denison, S.R., Phillips, L.A. and Smith, D.I. (2002) Evidence that instability within FRA3B extends four megabases. Oncogene, 21, 8713-8722.
-
(2002)
Oncogene
, vol.21
, pp. 8713-8722
-
-
Becker, N.A.1
Thorland, E.C.2
Denison, S.R.3
Phillips, L.A.4
Smith, D.I.5
-
17
-
-
0021690129
-
Constitutive fragile sites and cancer
-
Yunis, J.J. and Soreng, A.L. (1984) Constitutive fragile sites and cancer. Science, 226, 1199-1204.
-
(1984)
Science
, vol.226
, pp. 1199-1204
-
-
Yunis, J.J.1
Soreng, A.L.2
-
18
-
-
0023090923
-
Fragile sites, chromosome evolution, and human neoplasia
-
Mirò, R., Clemente, I.C., Fuster, C. and Egozcue, J. (1987) Fragile sites, chromosome evolution, and human neoplasia. Hum. Genet., 75, 345-349.
-
(1987)
Hum. Genet.
, vol.75
, pp. 345-349
-
-
Mirò, R.1
Clemente, I.C.2
Fuster, C.3
Egozcue, J.4
-
19
-
-
0000237085
-
Fragile sites in human chromosomes as regions of late-replicating DNA
-
Laird, C., Jaffe, E., Karpen, G., Lamb, M. and Nelson, R. (1987) Fragile sites in human chromosomes as regions of late-replicating DNA. Trends Genet., 3, 274-281.
-
(1987)
Trends Genet.
, vol.3
, pp. 274-281
-
-
Laird, C.1
Jaffe, E.2
Karpen, G.3
Lamb, M.4
Nelson, R.5
-
20
-
-
0031924605
-
Replication of a common fragile site, FRA3B, occurs late in S phase and is delayed further upon induction: Implications for the mechanism of fragile site induction
-
Le Beau, M.M., Rassool, F.V., Neilly, M.E., Espinosa, R. III., Glover, T.W., Smith, D.I. and McKeithan, T.W. (1998) Replication of a common fragile site, FRA3B, occurs late in S phase and is delayed further upon induction: implications for the mechanism of fragile site induction. Hum. Mol. Genet., 7, 755-761.
-
(1998)
Hum. Mol. Genet.
, vol.7
, pp. 755-761
-
-
Le Beau, M.M.1
Rassool, F.V.2
Neilly, M.E.3
Espinosa III, R.4
Glover, T.W.5
Smith, D.I.6
McKeithan, T.W.7
-
21
-
-
0034117095
-
Replication delay along FRA7H, a common fragile site on human chromosome 7, leads to chromosome instability
-
Hellman, A., Rahat, A., Scherer, S.W., Darvasi, A., Tsui, L.C. and Kerem, B. (2000) Replication delay along FRA7H, a common fragile site on human chromosome 7, leads to chromosome instability. Mol. Cell. Biol., 20, 4420-4427.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 4420-4427
-
-
Hellman, A.1
Rahat, A.2
Scherer, S.W.3
Darvasi, A.4
Tsui, L.C.5
Kerem, B.6
-
22
-
-
0037074013
-
ATR regulates fragile site stability
-
Casper, A.M., Nghiem, P., Arlt, M.F. and Glover, T.W. (2002) ATR regulates fragile site stability. Cell, 111, 779-789.
-
(2002)
Cell
, vol.111
, pp. 779-789
-
-
Casper, A.M.1
Nghiem, P.2
Arlt, M.F.3
Glover, T.W.4
-
23
-
-
3242712112
-
BRCA1 is required for common-fragile-site stability via its G2/M checkpoint function
-
Arlt, M.F., Xu, B., Durkin, S.G., Casper, A.M., Kastan, M.B. and Glover, T.W. (2004) BRCA1 is required for common-fragile-site stability via its G2/M checkpoint function. Mol. Cell. Biol., 24 6701-6709.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 6701-6709
-
-
Arlt, M.F.1
Xu, B.2
Durkin, S.G.3
Casper, A.M.4
Kastan, M.B.5
Glover, T.W.6
-
24
-
-
0027320551
-
A mammalian protein complex that repairs double-strand breaks and deletion by recombination
-
Jessberger, R., Podust, V., Hubscher, U. and Berg, P. (1993) A mammalian protein complex that repairs double-strand breaks and deletion by recombination. J. Biol. Chem., 268, 15070-15079.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 15070-15079
-
-
Jessberger, R.1
Podust, V.2
Hubscher, U.3
Berg, P.4
-
25
-
-
0033167929
-
Structural maintenance of chromosomes (SMC) proteins
-
Strunnikov, A.V. and Jessberger, R. (1999) Structural maintenance of chromosomes (SMC) proteins. Eur. J. Biochem., 263 6-13.
-
(1999)
Eur. J. Biochem.
, vol.263
, pp. 6-13
-
-
Strunnikov, A.V.1
Jessberger, R.2
-
26
-
-
0035954251
-
Sister chromatid cohesion is required for postreplicative double-strand break repair in Saccharomyces cerevisiae
-
Sjogren, C. and Nasmyth, K. (2001) Sister chromatid cohesion is required for postreplicative double-strand break repair in Saccharomyces cerevisiae. Curr. Biol., 11, 991-995.
-
(2001)
Curr. Biol.
, vol.11
, pp. 991-995
-
-
Sjogren, C.1
Nasmyth, K.2
-
27
-
-
0036500555
-
Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage
-
Kim, S.T., Xu, B. and Katan, M.B. (2002) Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage. Genes Dev., 16, 560-570.
-
(2002)
Genes Dev.
, vol.16
, pp. 560-570
-
-
Kim, S.T.1
Xu, B.2
Katan, M.B.3
-
28
-
-
0036500690
-
SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint
-
Yazdi, P.T., Wang, Y., Zhao, S., Patel, N., Lee, E.Y. and Qin, J.S. (2002) SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint. Genes Dev., 16, 571-582.
-
(2002)
Genes Dev.
, vol.16
, pp. 571-582
-
-
Yazdi, P.T.1
Wang, Y.2
Zhao, S.3
Patel, N.4
Lee, E.Y.5
Qin, J.S.6
-
29
-
-
0038581888
-
Inhibition of BUB1 results in genomic instability and anchorage-independent growth of normal human fibroblasts
-
Musio, A., Montagna, C., Zambroni, D., Indino, E., Barbieri, O., Citti, L., Villa, A., Ried, T. and Vezzoni, P. (2003) Inhibition of BUB1 results in genomic instability and anchorage-independent growth of normal human fibroblasts. Cancer Res., 63, 2855-2863.
-
(2003)
Cancer Res.
, vol.63
, pp. 2855-2863
-
-
Musio, A.1
Montagna, C.2
Zambroni, D.3
Indino, E.4
Barbieri, O.5
Citti, L.6
Villa, A.7
Ried, T.8
Vezzoni, P.9
-
30
-
-
0024519960
-
Fragile sites and statistics
-
Mariani, T. (1989) Fragile sites and statistics. Hum. Genet., 81, 319-322.
-
(1989)
Hum. Genet.
, vol.81
, pp. 319-322
-
-
Mariani, T.1
-
31
-
-
0033522135
-
Cloning and characterization of mammalian SMC1 and SMC3 genes and proteins, components of the DNA recombination complexes RC-1
-
Stursberg, S., Riwar, B. and Jessberger, R. (1999) Cloning and characterization of mammalian SMC1 and SMC3 genes and proteins, components of the DNA recombination complexes RC-1. Gene, 228 1-12.
-
(1999)
Gene
, vol.228
, pp. 1-12
-
-
Stursberg, S.1
Riwar, B.2
Jessberger, R.3
-
32
-
-
2942687831
-
Phosphorylation of SMC1 is a critical downstream event in the ATM-NBS1-BRCA1 pathway
-
Kitagawa, R., Bakkenist, C.J., Mckinnon, P.J. and Kastan M.B. (2004) Phosphorylation of SMC1 is a critical downstream event in the ATM-NBS1-BRCA1 pathway. Genes Dev., 18, 1423-1438.
-
(2004)
Genes Dev.
, vol.18
, pp. 1423-1438
-
-
Kitagawa, R.1
Bakkenist, C.J.2
Mckinnon, P.J.3
Kastan, M.B.4
-
33
-
-
0037178723
-
ATR homolog Mec1 promotes fork progression, thus averting breaks in replication slow zones
-
Cha, R.S. and Kleckner, N. (2002) ATR homolog Mec1 promotes fork progression, thus averting breaks in replication slow zones. Science, 29, 602-606.
-
(2002)
Science
, vol.29
, pp. 602-606
-
-
Cha, R.S.1
Kleckner, N.2
-
34
-
-
0037178718
-
Checking that replication breakdown is not terminal
-
Carr, A.M. (2002) Checking that replication breakdown is not terminal. Science, 297, 557-558.
-
(2002)
Science
, vol.297
, pp. 557-558
-
-
Carr, A.M.1
-
35
-
-
4544333154
-
Chromosomal instability at common fragile sites in Seckel syndrome
-
Casper, A.M., Durkin, S.G., Arlt, M.F. and Glover, T.W. (2004) Chromosomal instability at common fragile sites in Seckel syndrome. Am. J. Hum. Genet., 75, 654-660.
-
(2004)
Am. J. Hum. Genet.
, vol.75
, pp. 654-660
-
-
Casper, A.M.1
Durkin, S.G.2
Arlt, M.F.3
Glover, T.W.4
-
36
-
-
0032489520
-
DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
-
Rogakou, E.P., Pilch, D.R., Orr, A.H., Ivanova. V.S. and Bonner, W.M. (1998) DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J. Biol. Chem., 273, 5858-5868.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 5858-5868
-
-
Rogakou, E.P.1
Pilch, D.R.2
Orr, A.H.3
Ivanova, V.S.4
Bonner, W.M.5
-
37
-
-
0034623860
-
Response to RAG-mediated VDJ cleavage by NBS1 and γ-H2AX
-
Chen, H.T., Bhandoola, A., Difilippantonio, M.J., Zhu, J., Brown, M.J., Tai, X., Rogakou, E.P., Brotz, T.M., Bonner, W.M., Ried, T. and Nussenzweig, A. (2000) Response to RAG-mediated VDJ cleavage by NBS1 and γ-H2AX. Science, 290, 1962-1964.
-
(2000)
Science
, vol.290
, pp. 1962-1964
-
-
Chen, H.T.1
Bhandoola, A.2
Difilippantonio, M.J.3
Zhu, J.4
Brown, M.J.5
Tai, X.6
Rogakou, E.P.7
Brotz, T.M.8
Bonner, W.M.9
Ried, T.10
Nussenzweig, A.11
-
38
-
-
0035834693
-
ATM phosphorylates histone H2AX in response to DNA double-strand breaks
-
Burma, S., Chen, B.P., Murphy, M., Kurimasa, A. and Chen, D. (2001) ATM phosphorylates histone H2AX in response to DNA double-strand breaks. J. Biol. Chem., 276, 42462-42467.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 42462-42467
-
-
Burma, S.1
Chen, B.P.2
Murphy, M.3
Kurimasa, A.4
Chen, D.5
-
39
-
-
0037335861
-
Essential and dispensable roles of ATR in cell cycle arrest and genome maintenance
-
Brown, E.J. and Baltimore, D. (2003) Essential and dispensable roles of ATR in cell cycle arrest and genome maintenance. Genes Dev., 17, 615-628.
-
(2003)
Genes Dev.
, vol.17
, pp. 615-628
-
-
Brown, E.J.1
Baltimore, D.2
-
40
-
-
2542459341
-
Adaptation of a DNA replication checkpoint response depends upon inactivation of claspin by the polo-like kinase
-
Yoo, H.Y., Kumagai, A., Shevchenko, A., Shevchenko, A. and Dunphy, W.G. (2004) Adaptation of a DNA replication checkpoint response depends upon inactivation of claspin by the polo-like kinase. Cell, 117, 575-588.
-
(2004)
Cell
, vol.117
, pp. 575-588
-
-
Yoo, H.Y.1
Kumagai, A.2
Shevchenko, A.3
Shevchenko, A.4
Dunphy, W.G.5
-
41
-
-
0033361933
-
Common fragile sites: G-band characteristics within an R-band
-
Mishmar, D., Mandel-Gutfreund, Y., Margalit, H., Rahat, A. and Kerem, B. (1999) Common fragile sites: G-band characteristics within an R-band. Am. J. Hum. Genet., 64, 908-910.
-
(1999)
Am. J. Hum. Genet.
, vol.64
, pp. 908-910
-
-
Mishmar, D.1
Mandel-Gutfreund, Y.2
Margalit, H.3
Rahat, A.4
Kerem, B.5
-
42
-
-
0032508506
-
Structural maintenance of chromosomes protein C-terminal domains bind preferentially to DNA with secondary structure
-
Akhmedov, A.T., Frei, C., Tsai-Pflugfelder, M., Kemper, B., Gasser, S.M. and Jessberger, R. (1998) Structural maintenance of chromosomes protein C-terminal domains bind preferentially to DNA with secondary structure. J. Biol. Chem., 273, 24088-24094.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 24088-24094
-
-
Akhmedov, A.T.1
Frei, C.2
Tsai-Pflugfelder, M.3
Kemper, B.4
Gasser, S.M.5
Jessberger, R.6
-
43
-
-
0035803583
-
Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate
-
Elbashir, S.M., Martinez, J., Patkaniowska, A., Lendeckel, W. and Tuschl. T. (2001) Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate. EMBO J. 20, 6877-6888.
-
(2001)
EMBO J.
, vol.20
, pp. 6877-6888
-
-
Elbashir, S.M.1
Martinez, J.2
Patkaniowska, A.3
Lendeckel, W.4
Tuschl, T.5
-
44
-
-
0037884963
-
Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses
-
Rothkamm, K. and Löbrich, M. (2003) Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses. Proc. Natl Acad. Sci. USA, 100, 5057-5062.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 5057-5062
-
-
Rothkamm, K.1
Löbrich, M.2
-
45
-
-
0029214691
-
Electronic multi-confocal-points microscopy
-
Benedetti, P.A., Evangelista, V., Guidarini, D. and Vestri, S. (1995) Electronic multi-confocal-points microscopy. SPIE Proc., 2412, 56-62.
-
(1995)
SPIE Proc.
, vol.2412
, pp. 56-62
-
-
Benedetti, P.A.1
Evangelista, V.2
Guidarini, D.3
Vestri, S.4
-
46
-
-
0024367573
-
Report of the committee on cytogenetics markers
-
Sutherland, G.R. and Ledbetter, D.H. (1989) Report of the committee on cytogenetics markers. Cytogenet. Cell Genet., 51 452-458.
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(1989)
Cytogenet. Cell Genet.
, vol.51
, pp. 452-458
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Sutherland, G.R.1
Ledbetter, D.H.2
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