메뉴 건너뛰기




Volumn 239, Issue 3, 2014, Pages 253-263

WW domain-containing oxidoreductase's role in myriad cancers: Clinical significance and future implications

Author keywords

breast cancer; hypermethylation; lung cancer; tumor suppressor gene; WW domain containing oxidoreductase

Indexed keywords

ESTROGEN RECEPTOR; OXIDOREDUCTASE; PROGESTERONE RECEPTOR; TAMOXIFEN; TRANSCRIPTION FACTOR RUNX2;

EID: 84896035949     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: 10.1177/1535370213519213     Document Type: Article
Times cited : (57)

References (103)
  • 1
    • 77952536450 scopus 로고    scopus 로고
    • WWOX gene and gene product: tumor suppression through specific protein interactions
    • Salah Z,Aqeilan R,Huebner K.WWOX gene and gene product: tumor suppression through specific protein interactions.Future Oncol. 2010;6:249-59.
    • (2010) Future Oncol , vol.6 , pp. 249-259
    • Salah, Z.1    Aqeilan, R.2    Huebner, K.3
  • 2
    • 0034655131 scopus 로고    scopus 로고
    • WWOX, a novel WW domain-containing protein mapping to human chromosome 16q23.3-24.1, a region frequently affected in breast cancer
    • Bednarek AK,Laflin KJ,Daniel RL,Liao Q,Hawkins KA,Aldaz CM.WWOX, a novel WW domain-containing protein mapping to human chromosome 16q23.3-24.1, a region frequently affected in breast cancer.Cancer Res. 2000;60:2140-45.
    • (2000) Cancer Res , vol.60 , pp. 2140-2145
    • Bednarek, A.K.1    Laflin, K.J.2    Daniel, R.L.3    Liao, Q.4    Hawkins, K.A.5    Aldaz, C.M.6
  • 4
    • 0035793612 scopus 로고    scopus 로고
    • Hyaluronidase induction of a WW domain-containing oxidoreductase that enhances tumor necrosis factor cytotoxicity
    • Chang NS,Pratt N,Heath J,Schultz L,Sleve D,Carey GB,Zevotek N.Hyaluronidase induction of a WW domain-containing oxidoreductase that enhances tumor necrosis factor cytotoxicity.J Biol Chem. 2001;276:3361-70.
    • (2001) J Biol Chem , vol.276 , pp. 3361-3370
    • Chang, N.S.1    Pratt, N.2    Heath, J.3    Schultz, L.4    Sleve, D.5    Carey, G.B.6    Zevotek, N.7
  • 7
    • 13244271314 scopus 로고    scopus 로고
    • 17beta-Estradiol upregulates and activates WOX1/WWOXv1 and WOX2/WWOXv2 in vitro: potential role in cancerous progression of breast and prostate to a premetastatic state in vivo
    • Chang NS,Schultz L,Hsu LJ,Lewis J,Su M,Sze CI.17beta-Estradiol upregulates and activates WOX1/WWOXv1 and WOX2/WWOXv2 in vitro: potential role in cancerous progression of breast and prostate to a premetastatic state in vivo.Oncogene. 2005;24:714-23.
    • (2005) Oncogene , vol.24 , pp. 714-723
    • Chang, N.S.1    Schultz, L.2    Hsu, L.J.3    Lewis, J.4    Su, M.5    Sze, C.I.6
  • 9
    • 33846274591 scopus 로고    scopus 로고
    • Inhibition of breast cancer cell growth in vitro and in vivo: effect of restoration of Wwox expression
    • Iliopoulos D,Fabbri M,Druck T,Qin HR,Han SY,Huebner K.Inhibition of breast cancer cell growth in vitro and in vivo: effect of restoration of Wwox expression.Clin Cancer Res. 2007;13:268-74.
    • (2007) Clin Cancer Res , vol.13 , pp. 268-274
    • Iliopoulos, D.1    Fabbri, M.2    Druck, T.3    Qin, H.R.4    Han, S.Y.5    Huebner, K.6
  • 16
    • 34347371806 scopus 로고    scopus 로고
    • WWOX in biological control and tumorigenesis
    • Aqeilan RI,Croce CM.WWOX in biological control and tumorigenesis.J Cell Physiol. 2007;212:307-10.
    • (2007) J Cell Physiol , vol.212 , pp. 307-310
    • Aqeilan, R.I.1    Croce, C.M.2
  • 18
    • 70350463840 scopus 로고    scopus 로고
    • WWOX: its genomics, partners, and functions
    • Del Mare S,Salah Z,Aqeilan RI.WWOX: its genomics, partners, and functions.J Cell Biochem. 2009;108:737-45.
    • (2009) J Cell Biochem , vol.108 , pp. 737-745
    • Del Mare, S.1    Salah, Z.2    Aqeilan, R.I.3
  • 19
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • Hanahan D,Weinberg RA.Hallmarks of cancer: the next generation.Cell. 2011;144:646-74.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 20
    • 84872794645 scopus 로고    scopus 로고
    • Genetic alterations of the WWOX gene in breast cancer
    • Ekizoglu S,Muslumanoglu M,Dalay N,Buyru N.Genetic alterations of the WWOX gene in breast cancer.Med Oncol. 2012;29:1529-35.
    • (2012) Med Oncol , vol.29 , pp. 1529-1535
    • Ekizoglu, S.1    Muslumanoglu, M.2    Dalay, N.3    Buyru, N.4
  • 25
    • 84873261597 scopus 로고    scopus 로고
    • Genetic and epigenetic alterations of WWOX in the development of gastric cardia adenocarcinoma
    • Guo W,Dong Z,Dong Y,Guo Y,Kuang G,Yang Z.Genetic and epigenetic alterations of WWOX in the development of gastric cardia adenocarcinoma.Environ Mol Mutagen. 2013;54:112-23.
    • (2013) Environ Mol Mutagen , vol.54 , pp. 112-123
    • Guo, W.1    Dong, Z.2    Dong, Y.3    Guo, Y.4    Kuang, G.5    Yang, Z.6
  • 29
    • 59049087257 scopus 로고    scopus 로고
    • Association between CpG island methylation of the WWOX gene and its expression in breast cancers
    • Wang X,Chao L,Jin G,Ma G,Zang Y,Sun J.Association between CpG island methylation of the WWOX gene and its expression in breast cancers.Tumour Biol. 2009;30:8-14.
    • (2009) Tumour Biol , vol.30 , pp. 8-14
    • Wang, X.1    Chao, L.2    Jin, G.3    Ma, G.4    Zang, Y.5    Sun, J.6
  • 30
    • 84872202144 scopus 로고    scopus 로고
    • E3 ubiquitin ligase-mediated regulation of bone formation and tumorigenesis
    • Severe N,Dieudonne FX,Marie PJ.E3 ubiquitin ligase-mediated regulation of bone formation and tumorigenesis.Cell Death Dis. 2013;4:e463-e463.
    • (2013) Cell Death Dis , vol.4
    • Severe, N.1    Dieudonne, F.X.2    Marie, P.J.3
  • 31
    • 28544438918 scopus 로고    scopus 로고
    • Activated tyrosine kinase Ack1 promotes prostate tumorigenesis: role of Ack1 in polyubiquitination of tumor suppressor Wwox
    • Mahajan NP,Whang YE,Mohler JL,Earp HS.Activated tyrosine kinase Ack1 promotes prostate tumorigenesis: role of Ack1 in polyubiquitination of tumor suppressor Wwox.Cancer Res. 2005;65:10514-23.
    • (2005) Cancer Res , vol.65 , pp. 10514-10523
    • Mahajan, N.P.1    Whang, Y.E.2    Mohler, J.L.3    Earp, H.S.4
  • 32
    • 84860906122 scopus 로고    scopus 로고
    • Effects of multidisciplinary team working on breast cancer survival: retrospective, comparative, interventional cohort study of 13 722 women
    • Kesson EM,Allardice GM,George WD,Burns HJ,Morrison DS.Effects of multidisciplinary team working on breast cancer survival: retrospective, comparative, interventional cohort study of 13 722 women.BMJ. 2012;344:e2718-e2718.
    • (2012) BMJ , vol.344
    • Kesson, E.M.1    Allardice, G.M.2    George, W.D.3    Burns, H.J.4    Morrison, D.S.5
  • 36
    • 85047700355 scopus 로고    scopus 로고
    • Alternative transcripts of the candidate tumor suppressor gene, WWOX, are expressed at high levels in human breast tumors
    • Driouch K,Prydz H,Monese R,Johansen H,Lidereau R,Frengen E.Alternative transcripts of the candidate tumor suppressor gene, WWOX, are expressed at high levels in human breast tumors.Oncogene. 2002;21:1832-40.
    • (2002) Oncogene , vol.21 , pp. 1832-1840
    • Driouch, K.1    Prydz, H.2    Monese, R.3    Johansen, H.4    Lidereau, R.5    Frengen, E.6
  • 38
    • 8544283814 scopus 로고    scopus 로고
    • Physical and functional interactions between the Wwox tumor suppressor protein and the AP-2gamma transcription factor
    • Aqeilan RI,Palamarchuk A,Weigel RJ,Herrero JJ,Pekarsky Y,Croce CM.Physical and functional interactions between the Wwox tumor suppressor protein and the AP-2gamma transcription factor.Cancer Res. 2004;64:8256-61.
    • (2004) Cancer Res , vol.64 , pp. 8256-8261
    • Aqeilan, R.I.1    Palamarchuk, A.2    Weigel, R.J.3    Herrero, J.J.4    Pekarsky, Y.5    Croce, C.M.6
  • 39
    • 0038793721 scopus 로고    scopus 로고
    • Cancer and the FRA3B/FHIT fragile locus: it's a HIT
    • Huebner K,Croce CM.Cancer and the FRA3B/FHIT fragile locus: it's a HIT.Br J Cancer. 2003;88:1501-6.
    • (2003) Br J Cancer , vol.88 , pp. 1501-1506
    • Huebner, K.1    Croce, C.M.2
  • 46
    • 78751631889 scopus 로고    scopus 로고
    • The prognostic significance of WWOX expression in patients with breast cancer and its association with the basal-like phenotype
    • Wang X,Chao L,Ma G,Chen L,Zang Y,Sun J.The prognostic significance of WWOX expression in patients with breast cancer and its association with the basal-like phenotype.J Cancer Res Clin Oncol. 2011;137:271-8.
    • (2011) J Cancer Res Clin Oncol , vol.137 , pp. 271-278
    • Wang, X.1    Chao, L.2    Ma, G.3    Chen, L.4    Zang, Y.5    Sun, J.6
  • 48
    • 84874702740 scopus 로고    scopus 로고
    • Wwox expression may predict benefit from adjuvant tamoxifen in randomized breast cancer patients
    • Gothlin Eremo A,Wegman P,Stal O,Nordenskjold B,Fornander T,Wingren S.Wwox expression may predict benefit from adjuvant tamoxifen in randomized breast cancer patients.Oncol Rep. 2013;29:1467-74.
    • (2013) Oncol Rep , vol.29 , pp. 1467-1474
    • Gothlin Eremo, A.1    Wegman, P.2    Stal, O.3    Nordenskjold, B.4    Fornander, T.5    Wingren, S.6
  • 53
    • 59849113507 scopus 로고    scopus 로고
    • Genome-wide linkage scan for prostate cancer susceptibility from the University of Michigan Prostate Cancer Genetics Project: suggestive evidence for linkage at 16q23
    • Lange EM,Beebe-Dimmer JL,Ray AM,Zuhlke KA,Ellis J,Wang Y,Walters S,Cooney KA.Genome-wide linkage scan for prostate cancer susceptibility from the University of Michigan Prostate Cancer Genetics Project: suggestive evidence for linkage at 16q23.Prostate. 2009;69:385-91.
    • (2009) Prostate , vol.69 , pp. 385-391
    • Lange, E.M.1    Beebe-Dimmer, J.L.2    Ray, A.M.3    Zuhlke, K.A.4    Ellis, J.5    Wang, Y.6    Walters, S.7    Cooney, K.A.8
  • 56
    • 33646918047 scopus 로고    scopus 로고
    • Deletion and mutation of WWOX exons 6-8 in human non-small cell lung cancer
    • Zhou Y,Xu Y,Zhang Z.Deletion and mutation of WWOX exons 6-8 in human non-small cell lung cancer.J Huazhong Univ Sci Technol Med Sci. 2005;25:162-5.
    • (2005) J Huazhong Univ Sci Technol Med Sci , vol.25 , pp. 162-165
    • Zhou, Y.1    Xu, Y.2    Zhang, Z.3
  • 57
  • 58
    • 77949351023 scopus 로고    scopus 로고
    • Reversing effect of exogenous WWOX gene expression on malignant phenotype of primary cultured lung carcinoma cells
    • Zhou YL,Li YC,Shou F,Liu CQ,Pu Y,Tang H.Reversing effect of exogenous WWOX gene expression on malignant phenotype of primary cultured lung carcinoma cells.Chin Med J. 2010;123:615-20.
    • (2010) Chin Med J , vol.123 , pp. 615-620
    • Zhou, Y.L.1    Li, Y.C.2    Shou, F.3    Liu, C.Q.4    Pu, Y.5    Tang, H.6
  • 64
    • 77956505651 scopus 로고    scopus 로고
    • Bone lesions: benign and malignant
    • Gereige R,Kumar M.Bone lesions: benign and malignant.Pediatr Rev. 2010;31:355-62.
    • (2010) Pediatr Rev , vol.31 , pp. 355-362
    • Gereige, R.1    Kumar, M.2
  • 68
    • 78651373472 scopus 로고    scopus 로고
    • Evidence of molecular alterations in the tumour suppressor gene WWOX in benign and malignant bone related lesions of the jaws
    • Diniz MG,Borges ER,Pimenta FJ,De Mesquita Netto AC,De Marco L,Gomez RS,Gomes CC.Evidence of molecular alterations in the tumour suppressor gene WWOX in benign and malignant bone related lesions of the jaws.Oncol Rep. 2011;25:499-502.
    • (2011) Oncol Rep , vol.25 , pp. 499-502
    • Diniz, M.G.1    Borges, E.R.2    Pimenta, F.J.3    De Mesquita Netto, A.C.4    de Marco, L.5    Gomez, R.S.6    Gomes, C.C.7
  • 71
    • 84855690496 scopus 로고    scopus 로고
    • Role of the WWOX tumor suppressor gene in bone homeostasis and the pathogenesis of osteosarcoma
    • Del Mare S,Kurek KC,Stein GS,Lian JB,Aqeilan RI.Role of the WWOX tumor suppressor gene in bone homeostasis and the pathogenesis of osteosarcoma.Am J Cancer Res. 2011;1:585-94.
    • (2011) Am J Cancer Res , vol.1 , pp. 585-594
    • Del Mare, S.1    Kurek, K.C.2    Stein, G.S.3    Lian, J.B.4    Aqeilan, R.I.5
  • 74
    • 44449097274 scopus 로고    scopus 로고
    • Role of the WWOX gene, encompassing fragile region FRA16D, in suppression of pancreatic carcinoma cells
    • Nakayama S,Semba S,Maeda N,Aqeilan RI,Huebner K,Yokozaki H.Role of the WWOX gene, encompassing fragile region FRA16D, in suppression of pancreatic carcinoma cells.Cancer Sci. 2008;99:1370-76.
    • (2008) Cancer Sci , vol.99 , pp. 1370-1376
    • Nakayama, S.1    Semba, S.2    Maeda, N.3    Aqeilan, R.I.4    Huebner, K.5    Yokozaki, H.6
  • 76
    • 65549119551 scopus 로고    scopus 로고
    • Hypermethylation-mediated reduction of WWOX expression in intraductal papillary mucinous neoplasms of the pancreas
    • Nakayama S,Semba S,Maeda N,Matsushita M,Kuroda Y,Yokozaki H.Hypermethylation-mediated reduction of WWOX expression in intraductal papillary mucinous neoplasms of the pancreas.Br J Cancer. 2009;100:1438-43.
    • (2009) Br J Cancer , vol.100 , pp. 1438-1443
    • Nakayama, S.1    Semba, S.2    Maeda, N.3    Matsushita, M.4    Kuroda, Y.5    Yokozaki, H.6
  • 77
    • 77958000074 scopus 로고    scopus 로고
    • Loss of WW domain-containing oxidoreductase expression in the progression and development of gastric carcinoma: clinical and histopathologic correlations
    • Maeda N,Semba S,Nakayama S,Yanagihara K,Yokozaki H.Loss of WW domain-containing oxidoreductase expression in the progression and development of gastric carcinoma: clinical and histopathologic correlations.Virchows Arch. 2010;457:423-32.
    • (2010) Virchows Arch , vol.457 , pp. 423-432
    • Maeda, N.1    Semba, S.2    Nakayama, S.3    Yanagihara, K.4    Yokozaki, H.5
  • 78
    • 79955392330 scopus 로고    scopus 로고
    • Helicobacter pylori infection promotes methylation of WWOX gene in human gastric cancer
    • Yan J,Zhang M,Zhang J,Chen X,Zhang X.Helicobacter pylori infection promotes methylation of WWOX gene in human gastric cancer.Biochem Biophys Res Commun. 2011;408:99-102.
    • (2011) Biochem Biophys Res Commun , vol.408 , pp. 99-102
    • Yan, J.1    Zhang, M.2    Zhang, J.3    Chen, X.4    Zhang, X.5
  • 79
    • 84857963990 scopus 로고    scopus 로고
    • A WWOX-binding molecule, transmembrane protein 207, is related to the invasiveness of gastric signet-ring cell carcinoma
    • Takeuchi T,Adachi Y,Nagayama T.A WWOX-binding molecule, transmembrane protein 207, is related to the invasiveness of gastric signet-ring cell carcinoma.Carcinogenesis. 2012;33:548-54.
    • (2012) Carcinogenesis , vol.33 , pp. 548-554
    • Takeuchi, T.1    Adachi, Y.2    Nagayama, T.3
  • 82
    • 22344436709 scopus 로고    scopus 로고
    • WWOX mRNA expression profile in epithelial ovarian cancer supports the role of WWOX variant 1 as a tumour suppressor, although the role of variant 4 remains unclear
    • Gourley C,Paige AJ,Taylor KJ,Scott D,Francis NJ,Rush R,Aldaz CM,Smyth JF,Gabra H.WWOX mRNA expression profile in epithelial ovarian cancer supports the role of WWOX variant 1 as a tumour suppressor, although the role of variant 4 remains unclear.Int J Oncol. 2005;26:1681-9.
    • (2005) Int J Oncol , vol.26 , pp. 1681-1689
    • Gourley, C.1    Paige, A.J.2    Taylor, K.J.3    Scott, D.4    Francis, N.J.5    Rush, R.6    Aldaz, C.M.7    Smyth, J.F.8    Gabra, H.9
  • 83
    • 77956383594 scopus 로고    scopus 로고
    • Cloning of WWOX gene and its growth-inhibiting effects on ovarian cancer cells
    • Xiong Z,Hu S,Wang Z.Cloning of WWOX gene and its growth-inhibiting effects on ovarian cancer cells.J Huazhong Univ Sci Technol Med Sci. 2010;30:365-9.
    • (2010) J Huazhong Univ Sci Technol Med Sci , vol.30 , pp. 365-369
    • Xiong, Z.1    Hu, S.2    Wang, Z.3
  • 84
    • 84857186169 scopus 로고    scopus 로고
    • Aberrant expression of WWOX protein in epithelial ovarian cancer: a clinicopathologic and immunohistochemical study
    • Lan C,Chenggang W,Yulan B,Xiaohui D,Junhui Z,Xiao W.Aberrant expression of WWOX protein in epithelial ovarian cancer: a clinicopathologic and immunohistochemical study.Int J Gynecol Pathol. 2012;31:125-32.
    • (2012) Int J Gynecol Pathol , vol.31 , pp. 125-132
    • Lan, C.1    Chenggang, W.2    Yulan, B.3    Xiaohui, D.4    Junhui, Z.5    Xiao, W.6
  • 86
    • 84877081361 scopus 로고    scopus 로고
    • Effects of sodium valproate on the growth of human ovarian cancer cell line HO8910
    • Yan HC,Zhang J.Effects of sodium valproate on the growth of human ovarian cancer cell line HO8910.Asian Pacific J Cancer Prev. 2012;13:6429-33.
    • (2012) Asian Pacific J Cancer Prev , vol.13 , pp. 6429-6433
    • Yan, H.C.1    Zhang, J.2
  • 88
  • 91
    • 84896036893 scopus 로고    scopus 로고
    • Targeting deregulated epigenetic control in cancer: cancer epigenomics as a platform for risk assessment, early detection, targeted therapy and potential for relapse
    • Zaidi SK,van Wijnen AJ,Lian JB,Stein JL,Stein GS.Targeting deregulated epigenetic control in cancer: cancer epigenomics as a platform for risk assessment, early detection, targeted therapy and potential for relapse.J Cell Physiol.
    • J Cell Physiol
    • Zaidi, S.K.1    van Wijnen, A.J.2    Lian, J.B.3    Stein, J.L.4    Stein, G.S.5
  • 92
    • 84877254190 scopus 로고    scopus 로고
    • Integrated genomic characterization of endometrial carcinoma
    • National Human Genome Research I, Washington University School of M, University of Texas MDACC, University of P, University of North C, University of H, University Health N, International Genomics C, Cedars-Sinai Medical C, University of Texas MDACC, University of California SCBI, Institute for Systems B, University of Southern C, University of North C, Harvard Medical SB, Washington University in St L, Cancer Genome Atlas Research N, Genome sequencing centres
    • Cancer Genome Atlas Research N, Genome sequencing centres,Broad I,Getz G,Gabriel SB,Cibulskis K,Lander E,Sivachenko A,Sougnez C,Lawrence M,Washington University in St L,Kandoth C,Dooling D,Fulton R,Fulton L,Kalicki-Veizer J,McLellan MD,O'Laughlin M,Schmidt H,Wilson RK,Ye K,Ding L,Mardis ER.Cancer A,Ally A,Balasundaram M,Birol I,Butterfield YS,Carlsen R,Carter C,Chu A,Chuah E,Chun HJ,Dhalla N,Guin R,Hirst C,Holt RA,Jones SJ,Lee D,Li HI,Marra MA,Mayo M,Moore RA,Mungall AJ,Plettner P,Schein JE,Sipahimalani P,Tam A,Varhol RJ,Gordon Robertson A,Broad I,Cherniack AD,Pashtan I,Saksena G,Onofrio RC,Schumacher SE,Tabak B,Carter SL,Hernandez B,Gentry J,Salvesen HB,Ardlie K,Getz G,Winckler W,Beroukhim R,Gabriel SB,Meyerson M,Harvard Medical SB,Women's Hospital MDACC,Hadjipanayis A,Lee S,Mahadeshwar HS,Park P,Protopopov A,Ren X,Seth S,Song X,Tang J,Xi R,Yang L,Zeng D,Kucherlapati R,Chin L,Zhang J,University of North C,Todd Auman J,Balu S,Bodenheimer T,Buda E,Neil Hayes D,Hoyle AP,Jefferys SR,Jones CD,Meng S,Mieczkowski PA,Mose LE,Parker JS,Perou CM,Roach J,Shi Y,Simons JV,Soloway MG,Tan D,Topal MD,Waring S,Wu J,Hoadley KA,University of Southern C,Johns H,Baylin SB,Bootwalla MS,Lai PH,Triche TJ,Van Den Berg DJ,Weisenberger DJ,Laird PW,Shen H.Broad I,Chin L,Zhang J,Getz G,Cho J,Dicara D,Frazer S,Heiman D,Jing R,Lin P,Mallard W,Stojanov P,Voet D,Zhang H,Zou L,Noble M,Lawrence M,Institute for Systems B,Reynolds SM,Shmulevich I,Memorial Sloan-Kettering Cancer C,Arman Aksoy B,Antipin Y,Ciriello G,Dresdner G,Gao J,Gross B,Jacobsen A,Ladanyi M,Reva B,Sander C,Sinha R,Onur Sumer S,Taylor BS,Cerami E,Weinhold N,Schultz N,Shen R,University of California SCBI,Benz S,Goldstein T,Haussler D,Ng S,Szeto C,Stuart J,Benz CC,Yau C,University of Texas MDACC,Zhang W,Annala M,Broom BM,Casasent TD,Ju Z,Liang H,Liu G,Lu Y,Unruh AK,Wakefield C,Weinstein JN,Zhang N,Liu Y,Broaddus R,Akbani R,Mills GB.Nationwide Children's H,Adams C,Barr T,Black AD,Bowen J,Deardurff J,Frick J,Gastier-Foster JM,Grossman T,Harper HA,Hart-Kothari M,Helsel C,Hobensack A,Kuck H,Kneile K,Leraas KM,Lichtenberg TM,McAllister C,Pyatt RE,Ramirez NC,Tabler TR,Vanhoose N,White P,Wise L,Zmuda E,Tissue source sites A,Barnabas N,Berry-Green C,Blanc V,Boice L,Button M,Farkas A,Green A,Mackenzie J,Nicholson D,British Columbia Cancer A,Kalloger SE,Blake Gilks C,Cedars-Sinai Medical C,Karlan BY,Lester J,Orsulic S,Christiana C,Borowsky M,Cadungog M,Czerwinski C,Huelsenbeck-Dill L,Iacocca M,Petrelli N,Rabeno B,Witkin G,Cureline,Nemirovich-Danchenko E,Potapova O,Rotin D,Duke U,Berchuck A,Gynecologic Oncology G,Birrer M,Disaia P,Monovich L,International Genomics C,Curley E,Gardner J,Mallery D,Penny R,Mayo C,Dowdy SC,Winterhoff B,Dao L,Gostout B,Meuter A,Teoman A,Memorial Sloan-Kettering Cancer C,Dao F,Olvera N,Bogomolniy F,Garg K,Soslow RA,Levine DA.Abramov M,Ontario Tumour B,Bartlett JM,Kodeeswaran S,Parfitt J,St Petersburg Academic U,Moiseenko F,University Health N,Clarke BA,University of H,Goodman MT,Carney ME,Matsuno RK,University of North C,Fisher J,Huang M,Rathmell WK,Thorne L,Van Le L,University of P,Dhir R,Edwards R,Elishaev E,Zorn K,University of Texas MDACC,Broaddus R,Washington University School of M,Goodfellow PJ,Mutch D.Schultz N,Liu Y,Akbani R,Cherniack AD,Cerami E,Weinhold N,Shen H,Hoadley KA,Kahn AB,Bell DW,Pollock PM,Wang C,DAW,Shinbrot E,Karlan BY,Berchuck A,Dowdy SC,Winterhoff B,Goodman MT,Gordon Robertson A,Beroukhim R,Pashtan I,Salvesen HB,Laird PW,Noble M,Stuart J,Ding L,Kandoth C,Blake Gilks C,Soslow RA,Goodfellow PJ,Mutch D,Broaddus R,Zhang W,Mills GB,Kucherlapati R,Mardis ER,Levine DA.Ayala B,Chu AL,Jensen MA,Kothiyal P,Pihl TD,Pontius J,Pot DA,Snyder EE,Srinivasan D,Kahn AB.National Cancer I,Mills Shaw KR,Sheth M,Davidsen T,Eley Martin LFG,Demchok JA,Yang L,National Human Genome Research I,Guyer MS,Ozenberger BA,Sofia HJ,Writing c,Kandoth C,Schultz N,Cherniack AD,Akbani R,Liu Y,Shen H,Gordon Robertson A,Pashtan I,Shen R,Benz CC,Yau C,Laird PW,Ding L,Zhang W,Mills GB,Kucherlapati R,Mardis ER,Levine DA.Integrated genomic characterization of endometrial carcinoma.Nature. 2013;497:67-73.
    • (2013) Nature , vol.497 , pp. 67-73
    • Broad, I.1    Getz, G.2    Gabriel, S.B.3    Cibulskis, K.4    Lander, E.5    Sivachenko, A.6    Sougnez, C.7    Lawrence, M.8    Kandoth, C.9    Dooling, D.10    Fulton, R.11    Fulton, L.12    Kalicki-Veizer, J.13    McLellan, M.D.14    O'Laughlin, M.15    Schmidt, H.16    Wilson, R.K.17    Ye, K.18    Ding, L.19    Mardis, E.R.20    more..
  • 95
    • 84863111712 scopus 로고    scopus 로고
    • WWOX induces apoptosis and inhibits proliferation of human hepatoma cell line SMMC-7721
    • Hu BS,Tan JW,Zhu GH,Wang DF,Zhou X,Sun ZQ.WWOX induces apoptosis and inhibits proliferation of human hepatoma cell line SMMC-7721.World J Gastroenterol. 2012;18:3020-26.
    • (2012) World J Gastroenterol , vol.18 , pp. 3020-3026
    • Hu, B.S.1    Tan, J.W.2    Zhu, G.H.3    Wang, D.F.4    Zhou, X.5    Sun, Z.Q.6
  • 96
    • 84872664583 scopus 로고    scopus 로고
    • The expression and significance of WWOX and beta-catenin in hepatocellular carcinoma
    • Li YP,Wu CC,Chen WT,Huang YC,Chai CY.The expression and significance of WWOX and beta-catenin in hepatocellular carcinoma.APMIS. 2013;121:120-26.
    • (2013) APMIS , vol.121 , pp. 120-126
    • Li, Y.P.1    Wu, C.C.2    Chen, W.T.3    Huang, Y.C.4    Chai, C.Y.5
  • 99
    • 76749128434 scopus 로고    scopus 로고
    • Study of FHIT and WWOX expression in mucoepidermoid carcinoma and adenoid cystic carcinoma of salivary gland
    • Dincer N,Tezel GG,Sungur A,Himmetoglu C,Huebner K,Guler G.Study of FHIT and WWOX expression in mucoepidermoid carcinoma and adenoid cystic carcinoma of salivary gland.Oral Oncol. 2010;46:195-9.
    • (2010) Oral Oncol , vol.46 , pp. 195-199
    • Dincer, N.1    Tezel, G.G.2    Sungur, A.3    Himmetoglu, C.4    Huebner, K.5    Guler, G.6
  • 101
    • 84866156432 scopus 로고    scopus 로고
    • Overexpression of WW domain-containing oxidoreductase WOX1 preferentially induces apoptosis in human glioblastoma cells harboring mutant p53
    • Chiang MF,Yeh ST,Liao HF,Chang NS,Chen YJ.Overexpression of WW domain-containing oxidoreductase WOX1 preferentially induces apoptosis in human glioblastoma cells harboring mutant p53.Biomed Pharmacother. 2012;66:433-38.
    • (2012) Biomed Pharmacother , vol.66 , pp. 433-438
    • Chiang, M.F.1    Yeh, S.T.2    Liao, H.F.3    Chang, N.S.4    Chen, Y.J.5
  • 103
    • 84876223729 scopus 로고    scopus 로고
    • The role of the WWOX gene in leukemia and its mechanisms of action
    • Cui Z,Lin D,Cheng F,Luo L,Kong L,Xu J,Hu J,Lan F.The role of the WWOX gene in leukemia and its mechanisms of action.Oncol Rep. 2013;29:2154-62.
    • (2013) Oncol Rep , vol.29 , pp. 2154-2162
    • Cui, Z.1    Lin, D.2    Cheng, F.3    Luo, L.4    Kong, L.5    Xu, J.6    Hu, J.7    Lan, F.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.