-
1
-
-
84903277019
-
Human schistosomiasis
-
Colley, D.G.; Bustinduy, A.L.; Secor, W.E.; King, C.H. Human schistosomiasis. Lancet 2014, 383, 2253-2264.
-
(2014)
Lancet
, vol.383
, pp. 2253-2264
-
-
Colley, D.G.1
Bustinduy, A.L.2
Secor, W.E.3
King, C.H.4
-
2
-
-
84949102352
-
-
Available online accessed on 10 December 2014
-
WHO Schistosomiasis. 2014, Fact Sheet. Available online: http://www.who.int/mediacentre/ factsheets/fs115/en (accessed on 10 December 2014).
-
(2014)
Fact Sheet
-
-
WHO Schistosomiasis1
-
3
-
-
33748757526
-
Human schistosomiasis
-
Gryseels, B.; Polman, K.; Clerinx, J.; Kestens, L. Human schistosomiasis. Lancet 2006, 368, 1106-1118.
-
(2006)
Lancet
, vol.368
, pp. 1106-1118
-
-
Gryseels, B.1
Polman, K.2
Clerinx, J.3
Kestens, L.4
-
4
-
-
0037129443
-
Schistosomiasis
-
Ross, A.G.P.; Bartley, P.B.; Sleigh, A.C.; Olds, G.R.; Li, Y.; Williams, G.M.; McManus, D.P. Schistosomiasis. N. Engl. J. Med. 2002, 346, 1212-1120.
-
(2002)
N. Engl. J. Med.
, vol.346
, pp. 1212-11120
-
-
Ross, A.G.P.1
Bartley, P.B.2
Sleigh, A.C.3
Olds, G.R.4
Li, Y.5
Williams, G.M.6
McManus, D.P.7
-
5
-
-
0017622884
-
Praziquantel, a new board-spectrum antischistosomal agent
-
Gönnert, R.; Andrews, P. Praziquantel, a new board-spectrum antischistosomal agent. Z. Parasitenkd. 1977, 52, 129-150.
-
(1977)
Z. Parasitenkd
, vol.52
, pp. 129-150
-
-
Gönnert, R.1
Andrews, P.2
-
6
-
-
80051690024
-
Macromolecular bases of antischistosomal therapy
-
Angelucci, F.; Miele, A.E.; Boumis, G.; Brunori, M.; Dimastrogiovanni, D.; Bellelli, A. Macromolecular bases of antischistosomal therapy. Curr. Top. Med. Chem. 2011, 11, 2012-2028.
-
(2011)
Curr. Top. Med. Chem.
, vol.11
, pp. 2012-2028
-
-
Angelucci, F.1
Miele, A.E.2
Boumis, G.3
Brunori, M.4
Dimastrogiovanni, D.5
Bellelli, A.6
-
7
-
-
82955212953
-
Effect of praziquantel prolonged administration on granuloma formation around Schistosoma japonicum eggs in lung of sensitized mice
-
Huang, Y.; Xu, Y.; Yu, C.; Li, H.; Yin, X.; Wang, T.; Wang, W.; Liang, Y. Effect of praziquantel prolonged administration on granuloma formation around Schistosoma japonicum eggs in lung of sensitized mice. Parasitol. Res. 2011, 109, 1453-1459.
-
(2011)
Parasitol. Res.
, vol.109
, pp. 1453-1459
-
-
Huang, Y.1
Xu, Y.2
Yu, C.3
Li, H.4
Yin, X.5
Wang, T.6
Wang, W.7
Liang, Y.8
-
8
-
-
84866016930
-
Therapeutic effect of alpha lipoic acid combined with praziquantel on liver fibrosis induced by Schistosoma mansoni challenged mice
-
Abdel-Hafeez, E.H.; Ahmad, A.K.; Abdulla, A.M.; Aabdel-Wahab, S.; Mosalem, F.A. Therapeutic effect of alpha lipoic acid combined with praziquantel on liver fibrosis induced by Schistosoma mansoni challenged mice. Parasitol. Res. 2012, 111, 577-586.
-
(2012)
Parasitol. Res.
, vol.111
, pp. 577-586
-
-
Abdel-Hafeez, E.H.1
Ahmad, A.K.2
Abdulla, A.M.3
Aabdel-Wahab, S.4
Mosalem, F.A.5
-
9
-
-
0029738033
-
Characterization of isolates of Schistosoma mansoni from Egyptian villagers that tolerate high doses of praziquantel
-
Ismail, M.; Metwally, A.; Farghaly, A.; Bruce, J.; Tao, L.F.; Bennett, J.L. Characterization of isolates of Schistosoma mansoni from Egyptian villagers that tolerate high doses of praziquantel. Am. J. Trop. Med. Hyg. 1996, 55, 214-218.
-
(1996)
Am. J. Trop. Med. Hyg.
, vol.55
, pp. 214-218
-
-
Ismail, M.1
Metwally, A.2
Farghaly, A.3
Bruce, J.4
Tao, L.F.5
Bennett, J.L.6
-
10
-
-
70449510166
-
Reduced susceptibility to praziquantel among naturally occurring Kenyan isolates of Schistosoma mansoni
-
Melman, S.D.; Steinauer, M.L.; Cunningham, C.; Kubatko, L.S.; Mwangi, I.N.; Wynn, N.B.; Mutuku, M.W.; Karanja, D.M.S.; Colley, D.G.; Black, C.L.; et al. Reduced susceptibility to praziquantel among naturally occurring Kenyan isolates of Schistosoma mansoni. PLoS Negl. Trop. Dis. 2009, 3, e504.
-
(2009)
PLoS Negl. Trop. Dis.
, vol.3
, pp. e504
-
-
Melman, S.D.1
Steinauer, M.L.2
Cunningham, C.3
Kubatko, L.S.4
Mwangi, I.N.5
Wynn, N.B.6
Mutuku, M.W.7
Karanja, D.M.S.8
Colley, D.G.9
Black, C.L.10
-
11
-
-
0029009379
-
Short report: Diminished susceptibility to praziquantel in a Senegal isolate of Schistosoma mansoni
-
Fallon, P.G.; Sturrock, R.F.; Niang, A.C.; Doenhoff, M.J. Short report: Diminished susceptibility to praziquantel in a Senegal isolate of Schistosoma mansoni. Am. J. Trop. Med. Hyg. 1995, 53, 61-62.
-
(1995)
Am. J. Trop. Med. Hyg.
, vol.53
, pp. 61-62
-
-
Fallon, P.G.1
Sturrock, R.F.2
Niang, A.C.3
Doenhoff, M.J.4
-
12
-
-
79955389741
-
Schistosoma mansoni: A method for inducing resistance to praziquantel using infected Biomphalaria glabrata snails
-
Couto, F.F.B.; Coelho, P.M.Z.; Araújo, N.; Kusel, J.R.; Katz, N.; Jannotti-Passos, L.K.; Mattos, A.C.A. Schistosoma mansoni: A method for inducing resistance to praziquantel using infected Biomphalaria glabrata snails. Mem. Inst. Oswaldo Cruz 2011, 106, 153-157.
-
(2011)
Mem. Inst. Oswaldo Cruz
, vol.106
, pp. 153-157
-
-
Couto, F.F.B.1
Coelho, P.M.Z.2
Araújo, N.3
Kusel, J.R.4
Katz, N.5
Jannotti-Passos, L.K.6
Mattos, A.C.A.7
-
13
-
-
0028025029
-
Drug-resistant schistosomiasis: Resistance to praziquantel and oxamniquine induced in Schistosoma mansoni in mice is drug specific
-
Fallon, P.G.; Doenhoff, M.J. Drug-resistant schistosomiasis: Resistance to praziquantel and oxamniquine induced in Schistosoma mansoni in mice is drug specific. Am. J. Trop. Med. Hyg. 1994, 51, 83-88.
-
(1994)
Am. J. Trop. Med. Hyg.
, vol.51
, pp. 83-88
-
-
Fallon, P.G.1
Doenhoff, M.J.2
-
14
-
-
0028719106
-
Laboratory induced resistance to praziquantel in experimental schistosomiasis
-
Ismail, M.M.; Taha, S.A.; Farghaly, A.M.; El-Azony, A.S. Laboratory induced resistance to praziquantel in experimental schistosomiasis. J. Egypt. Soc. Parasitol. 1994, 24, 685-695.
-
(1994)
J. Egypt. Soc. Parasitol.
, vol.24
, pp. 685-695
-
-
Ismail, M.M.1
Taha, S.A.2
Farghaly, A.M.3
El-Azony, A.S.4
-
15
-
-
80052091736
-
Rule-based classification of chemical structures by scaffold
-
Schuffenhauer, A.; Varin, T. Rule-Based Classification of Chemical Structures by Scaffold. Mol. Inf. 2011, 47, 646-664.
-
(2011)
Mol. Inf.
, vol.47
, pp. 646-664
-
-
Schuffenhauer, A.1
Varin, T.2
-
16
-
-
84858308226
-
Natural products as sources of new drugs over the 30 years from 1981 to 2010
-
Newman, D.J.; Cragg, G.M. Natural products as sources of new drugs over the 30 years from 1981 to 2010. J. Nat. Prod. 2012, 75, 311-335.
-
(2012)
J. Nat. Prod.
, vol.75
, pp. 311-335
-
-
Newman, D.J.1
Cragg, G.M.2
-
17
-
-
52049109838
-
Natural products in drug discovery
-
Harvey, A.L. Natural products in drug discovery. Drug Discov. Today 2008, 13, 894-901.
-
(2008)
Drug Discov. Today
, vol.13
, pp. 894-901
-
-
Harvey, A.L.1
-
18
-
-
77956395112
-
Natural products in modern life science
-
Bohlin, L.; Göransson, U.; Alsmark, C.; Wedén, C.; Backlund, A. Natural products in modern life science. Phytochem. Rev. 2010, 9, 279-301.
-
(2010)
Phytochem. Rev.
, vol.9
, pp. 279-301
-
-
Bohlin, L.1
Göransson, U.2
Alsmark, C.3
Wedén, C.4
Backlund, A.5
-
19
-
-
77952830186
-
Current strategies for drug discovery through natural products
-
Harvey, A.L.; Clark, R.L.; Mackay, S.P.; Johnston, B.F. Current strategies for drug discovery through natural products. Expert Opin. Drug Discov. 2010, 5, 559-568.
-
(2010)
Expert Opin. Drug Discov.
, vol.5
, pp. 559-568
-
-
Harvey, A.L.1
Clark, R.L.2
Mackay, S.P.3
Johnston, B.F.4
-
20
-
-
0037029340
-
Ivermectin, a broad spectrum antiparasitic drug
-
Datry, A.; Thellier, M.; Alfa-Cissé, O.; Danis, M.; Caumes, E. Ivermectin, a broad spectrum antiparasitic drug. Press. Méd. 2002, 31, 607-611.
-
(2002)
Press Méd.
, vol.31
, pp. 607-611
-
-
Datry, A.1
Thellier, M.2
Alfa-Cissé, O.3
Danis, M.4
Caumes, E.5
-
21
-
-
11344292132
-
The role of natural product chemistry in drug discovery
-
Butler, M.S. The role of natural product chemistry in drug discovery. J. Nat. Prod. 2004, 67, 2141-2153.
-
(2004)
J. Nat. Prod.
, vol.67
, pp. 2141-2153
-
-
Butler, M.S.1
-
22
-
-
80054923170
-
Modern drug discovery technologies: Opportunities and challenges in lead discovery
-
Guido, R.V.C.; Oliva, G.; Andricopulo, A.D. Modern drug discovery technologies: Opportunities and challenges in lead discovery. Comb. Chem. High Throughput Screen. 2011, 14, 830-839.
-
(2011)
Comb. Chem. High Throughput Screen.
, vol.14
, pp. 830-839
-
-
Guido, R.V.C.1
Oliva, G.2
Andricopulo, A.D.3
-
23
-
-
36348987143
-
The value of natural products to future pharmaceutical discovery
-
Baker, D.D.; Chu, M.; Oza, U.; Rajgarhia, V. The value of natural products to future pharmaceutical discovery. Nat. Prod. Rep. 2007, 24, 1225-1244.
-
(2007)
Nat. Prod. Rep.
, vol.24
, pp. 1225-1244
-
-
Baker, D.D.1
Chu, M.2
Oza, U.3
Rajgarhia, V.4
-
24
-
-
42949149681
-
Modern natural products chemistry and drug discovery
-
Ojima, I. Modern natural products chemistry and drug discovery. J. Med. Chem. 2008, 51, 2587-2588.
-
(2008)
J. Med. Chem.
, vol.51
, pp. 2587-2588
-
-
Ojima, I.1
-
25
-
-
84921653624
-
-
Available online accessed on 12 December 2014
-
TimTec Natural Products Library. Available online: http://www.timtec.net/natural-compound-library.htm (accessed on 12 December 2014).
-
-
-
TimTec Natural Products Library1
-
26
-
-
84921672455
-
-
Available online accessed on 10 December 2014
-
IBScreen Natural Products. Available online: http://www.ibscreen.com/index.htm (accessed on 10 December 2014).
-
-
-
IBScreen Natural Products1
-
27
-
-
84921672454
-
-
Available online accessed on 10 December 2014
-
Specs Natural Products. Available online: http://www.specs.net/ (accessed on 10 December 2014).
-
-
-
Specs Natural Products1
-
28
-
-
78049522482
-
Identification of bioactive natural products by pharmacophore-based virtual screening
-
Schuster, D.; Wolber, G. Identification of bioactive natural products by pharmacophore-based virtual screening. Curr. Pharm. Des. 2010, 16, 1666-1681.
-
(2010)
Curr. Pharm. Des.
, vol.16
, pp. 1666-1681
-
-
Schuster, D.1
Wolber, G.2
-
29
-
-
84855824565
-
Natural products of dietary origin as lead compounds in virtual screening and drug design
-
Geldenhuys, W.J.; Bishayee, A.; Darvesh, A.S.; Carroll, R.T. Natural products of dietary origin as lead compounds in virtual screening and drug design. Curr. Pharm. Biotechnol. 2012, 13, 117-124.
-
(2012)
Curr. Pharm. Biotechnol.
, vol.13
, pp. 117-124
-
-
Geldenhuys, W.J.1
Bishayee, A.2
Darvesh, A.S.3
Carroll, R.T.4
-
30
-
-
84875084369
-
Natural products as a source for treating neglected parasitic diseases
-
Ndjonka, D.; Rapado, L.N.; Silber, A.M.; Liebau, E.; Wrenger, C. Natural products as a source for treating neglected parasitic diseases. Int. J. Mol. Sci. 2013, 14, 3395-3439.
-
(2013)
Int. J. Mol. Sci.
, vol.14
, pp. 3395-3439
-
-
Ndjonka, D.1
Rapado, L.N.2
Silber, A.M.3
Liebau, E.4
Wrenger, C.5
-
31
-
-
0015820846
-
A comparative study of the reproductive system of mature, immature and "unisexual" female Schistosoma mansoni
-
Erasmus, D.A. A comparative study of the reproductive system of mature, immature and "unisexual" female Schistosoma mansoni. Parasitology 1973, 67, 165-183.
-
(1973)
Parasitology
, vol.67
, pp. 165-183
-
-
Erasmus, D.A.1
-
32
-
-
84893789834
-
Serotonin signaling in Schistosoma mansoni: A serotonin-activated G protein-coupled receptor controls parasite movement
-
Patocka, N.; Sharma, N.; Rashid, M.; Ribeiro, P. Serotonin signaling in Schistosoma mansoni: A serotonin-activated G protein-coupled receptor controls parasite movement. PLoS Pathog. 2014, 10, e1003878.
-
(2014)
PLoS Pathog.
, vol.10
, pp. e1003878
-
-
Patocka, N.1
Sharma, N.2
Rashid, M.3
Ribeiro, P.4
-
33
-
-
84885386465
-
Neurotransmitter transporters in schistosomes: Structure, function and prospects for drug discovery
-
Ribeiro, P.; Patocka, N. Neurotransmitter transporters in schistosomes: Structure, function and prospects for drug discovery. Parasitol. Int. 2013, 62, 629-638.
-
(2013)
Parasitol. Int.
, vol.62
, pp. 629-638
-
-
Ribeiro, P.1
Patocka, N.2
-
34
-
-
70350244564
-
Schistosoma genomics: New perspectives on schistosome biology and host-parasite interaction
-
Han, Z.-G.; Brindley, P.J.; Wang, S.-Y.; Chen, Z. Schistosoma genomics: New perspectives on schistosome biology and host-parasite interaction. Annu. Rev. Genomics Hum. Genet. 2009, 10, 211-240.
-
(2009)
Annu. Rev. Genomics Hum. Genet.
, vol.10
, pp. 211-240
-
-
Han, Z.-G.1
Brindley, P.J.2
Wang, S.-Y.3
Chen, Z.4
-
35
-
-
0033035094
-
Artemisinin drugs in the treatment of malaria: From medicinal herb to registered medication
-
Van Agtmael, M.A.; Eggelte, T.A.; van Boxtel, C.J. Artemisinin drugs in the treatment of malaria: From medicinal herb to registered medication. Trends Pharmacol. Sci. 1999, 20, 199-205.
-
(1999)
Trends Pharmacol. Sci.
, vol.20
, pp. 199-205
-
-
Van Agtmael, M.A.1
Eggelte, T.A.2
Van Boxtel, C.J.3
-
36
-
-
84896719929
-
Artemisinins: Pharmacological actions beyond anti-malarial
-
Ho, W.E.; Peh, H.Y.; Chan, T.K.; Wong, W.S. F. Artemisinins: Pharmacological actions beyond anti-malarial. Pharmacol. Ther. 2014, 142, 126-139.
-
(2014)
Pharmacol. Ther.
, vol.142
, pp. 126-139
-
-
Ho, W.E.1
Peh, H.Y.2
Chan, T.K.3
Wong, W.S.F.4
-
37
-
-
84865988767
-
Qinghaosu (artemisinin): Chemistry and pharmacology
-
Li, Y. Qinghaosu (artemisinin): Chemistry and pharmacology. Acta Pharmacol. Sin. 2012, 33, 1141-1146.
-
(2012)
Acta Pharmacol. Sin.
, vol.33
, pp. 1141-1146
-
-
Li, Y.1
-
38
-
-
84896972390
-
Tegumentary changes in two different strains of Schistosoma mansoni treated with artemisinin and artesunic acid
-
Frezza, T.F.; Fernandes de Oliveira, C.N.; Banin, T.M.; Garcia Rehder, V.L.; Boaventura, S., Jr.; Allegretti, S.M. Tegumentary changes in two different strains of Schistosoma mansoni treated with artemisinin and artesunic acid. Rev. Patol. Trop. 2013, 42, 309-321.
-
(2013)
Rev. Patol. Trop.
, vol.42
, pp. 309-321
-
-
Frezza, T.F.1
Fernandes De Oliveira, C.N.2
Banin, T.M.3
Garcia Rehder, V.L.4
Boaventura, S.5
Allegretti, S.M.6
-
39
-
-
79952664817
-
In-vivo activity of dihydroartemisinin against Schistosoma japonicum
-
Li, H.-J.; Wang, W.; Qu, G.-L.; Tao, Y.-H.; Xing, Y.-T.; Li, Y.-Z.; Wei, J.-Y.; Dai, J.-R.; Liang, Y.-S. In-vivo activity of dihydroartemisinin against Schistosoma japonicum. Ann. Trop. Med. Parasitol. 2011, 105, 181-185.
-
(2011)
Ann. Trop. Med. Parasitol.
, vol.105
, pp. 181-185
-
-
Li, H.-J.1
Wang, W.2
Qu, G.-L.3
Tao, Y.-H.4
Xing, Y.-T.5
Li, Y.-Z.6
Wei, J.-Y.7
Dai, J.-R.8
Liang, Y.-S.9
-
40
-
-
84863474441
-
Effect of the in vivo activity of dihydroartemisinin against Schistosoma mansoni infection in mice
-
Li, H.; Wang, W.; Qu, G.; Li, Y.; Tao, Y.; Xing, Y.; Wang, X.; Dai, Y.; Wei, J.; Dai, J.; et al. Effect of the in vivo activity of dihydroartemisinin against Schistosoma mansoni infection in mice. Parasitol. Res. 2012, 110, 1727-1732.
-
(2012)
Parasitol. Res.
, vol.110
, pp. 1727-1732
-
-
Li, H.1
Wang, W.2
Qu, G.3
Li, Y.4
Tao, Y.5
Xing, Y.6
Wang, X.7
Dai, Y.8
Wei, J.9
Dai, J.10
-
41
-
-
84921671790
-
Experimental studies on antischistosomal activity of qinghaosu
-
Chen, D.J.; Fu, L.F.; Shao, P.P.; Wu, F.Z.; Fan, C.Z.; Shu, H.; Ren, C.X.; Sheng, X.L. Experimental studies on antischistosomal activity of qinghaosu. Chin. Med. J. (Engl.) 1980, 60, 4222-4425.
-
(1980)
Chin. Med. J. (Engl.)
, vol.60
, pp. 4222-4425
-
-
Chen, D.J.1
Fu, L.F.2
Shao, P.P.3
Wu, F.Z.4
Fan, C.Z.5
Shu, H.6
Ren, C.X.7
Sheng, X.L.8
-
42
-
-
31044454267
-
Evaluation of the anthelmintic effects of artesunate against experimental Schistosoma mansoni infection in mice using different treatment protocols
-
Shaohong, L.; Kumagai, T.; Qinghua, A.; Xiaolan, Y.; Ohmae, H.; Yabu, Y.; Siwen, L.; Liyong, W.; Maruyama, H.; Ohta, N. Evaluation of the anthelmintic effects of artesunate against experimental Schistosoma mansoni infection in mice using different treatment protocols. Parasitol. Int. 2006, 55, 63-68.
-
(2006)
Parasitol. Int.
, vol.55
, pp. 63-68
-
-
Shaohong, L.1
Kumagai, T.2
Qinghua, A.3
Xiaolan, Y.4
Ohmae, H.5
Yabu, Y.6
Siwen, L.7
Liyong, W.8
Maruyama, H.9
Ohta, N.10
-
43
-
-
84895510569
-
Efficacy of artemether and artesunate in mice infected with praziquantel non-susceptible isolate of Schistosoma japonicum
-
Wang, W.; Li, T.-Y.; Ji, Y.; Qu, G.-L.; Qian, Y.-L.; Li, H.-J.; Dai, J.-R.; Liang, Y.-S. Efficacy of artemether and artesunate in mice infected with praziquantel non-susceptible isolate of Schistosoma japonicum. Parasitol. Res. 2014, 113, 925-931.
-
(2014)
Parasitol. Res.
, vol.113
, pp. 925-931
-
-
Wang, W.1
Li, T.-Y.2
Ji, Y.3
Qu, G.-L.4
Qian, Y.-L.5
Li, H.-J.6
Dai, J.-R.7
Liang, Y.-S.8
-
44
-
-
21544479736
-
Effects of praziquantel and artesunate on the tegument of adult Schistosoma mekongi harboured in mice
-
Jiraungkoorskul, W.; Sahaphong, S.; Sobhon, P.; Riengrojpitak, S.; Kangwanrangsan, N. Effects of praziquantel and artesunate on the tegument of adult Schistosoma mekongi harboured in mice. Parasitol. Int. 2005, 54, 177-183.
-
(2005)
Parasitol. Int.
, vol.54
, pp. 177-183
-
-
Jiraungkoorskul, W.1
Sahaphong, S.2
Sobhon, P.3
Riengrojpitak, S.4
Kangwanrangsan, N.5
-
45
-
-
0034599096
-
Preventive effect of artemether in experimental animals infected with Schistosoma mansoni
-
Shuhua, X.; Chollet, J.; Weiss, N.; Bergquist, R.N.; Tanner, M. Preventive effect of artemether in experimental animals infected with Schistosoma mansoni. Parasitol. Int. 2000, 49, 19-24.
-
(2000)
Parasitol. Int.
, vol.49
, pp. 19-24
-
-
Shuhua, X.1
Chollet, J.2
Weiss, N.3
Bergquist, R.N.4
Tanner, M.5
-
46
-
-
84882239760
-
In vivo effect of single oral dose of artemether against early juvenile stages of Schistosoma mansoni Egyptian strain
-
El-Beshbishi, S.N.; Taman, A.; El-Malky, M.; Azab, M.S.; El-Hawary, A.K.; El-Tantawy, D. In vivo effect of single oral dose of artemether against early juvenile stages of Schistosoma mansoni Egyptian strain. Exp. Parasitol. 2013, 135, 240-245.
-
(2013)
Exp. Parasitol.
, vol.135
, pp. 240-245
-
-
El-Beshbishi, S.N.1
Taman, A.2
El-Malky, M.3
Azab, M.S.4
El-Hawary, A.K.5
El-Tantawy, D.6
-
47
-
-
0033841737
-
Effect of artemether against Schistosoma haematobium in experimentally infected hamsters
-
Shuhua, X.; Utzinger, J.; Chollet, J.; Endriss, Y.; N'Goran, E.K.; Tanner, M. Effect of artemether against Schistosoma haematobium in experimentally infected hamsters. Int. J. Parasitol. 2000, 30, 1001-1006.
-
(2000)
Int. J. Parasitol.
, vol.30
, pp. 1001-1006
-
-
Shuhua, X.1
Utzinger, J.2
Chollet, J.3
Endriss, Y.4
N'Goran, E.K.5
Tanner, M.6
-
48
-
-
33947314662
-
Effect of artemether on the tegument of adult Schistosoma haematobium recovered from mice
-
Xiao, S.-H.; Tanner, M.; Shen, B.-G.; Utzinger, J.; Chollet, J. Effect of artemether on the tegument of adult Schistosoma haematobium recovered from mice. Chin. J. Parasitol. Parasit. Dis. 2006, 24, 425-432.
-
(2006)
Chin. J. Parasitol. Parasit. Dis.
, vol.24
, pp. 425-432
-
-
Xiao, S.-H.1
Tanner, M.2
Shen, B.-G.3
Utzinger, J.4
Chollet, J.5
-
49
-
-
80052313469
-
Effects of artemether, artesunate and dihydroartemisinin administered orally at multiple doses or combination in treatment of mice infected with Schistosoma japonicum
-
Li, H.-J.; Wang, W.; Li, Y.-Z.; Qu, G.-L.; Xing, Y.-T.; Tao, Y.-H.; Wei, J.-Y.; Dai, J.-R.; Liang, Y.-S. Effects of artemether, artesunate and dihydroartemisinin administered orally at multiple doses or combination in treatment of mice infected with Schistosoma japonicum. Parasitol. Res. 2011, 109, 515-519.
-
(2011)
Parasitol. Res.
, vol.109
, pp. 515-519
-
-
Li, H.-J.1
Wang, W.2
Li, Y.-Z.3
Qu, G.-L.4
Xing, Y.-T.5
Tao, Y.-H.6
Wei, J.-Y.7
Dai, J.-R.8
Liang, Y.-S.9
-
50
-
-
0344451208
-
Schistosoma japonicum: In vitro effects of artemether combined with haemin depend on cultivation media and appraisal of artemether products appearing in the media
-
Xiao, S.-H.; Wu, Y.-L.; Tanner, M.; Wu, W.-M.; Utzinger, J.; Mei, J.-Y.; Scorneaux, B.; Chollet, J.; Zhai, Z. Schistosoma japonicum: In vitro effects of artemether combined with haemin depend on cultivation media and appraisal of artemether products appearing in the media. Parasitol. Res. 2003, 89, 459-466.
-
(2003)
Parasitol. Res.
, vol.89
, pp. 459-466
-
-
Xiao, S.-H.1
Wu, Y.-L.2
Tanner, M.3
Wu, W.-M.4
Utzinger, J.5
Mei, J.-Y.6
Scorneaux, B.7
Chollet, J.8
Zhai, Z.9
-
51
-
-
0035725313
-
Artemether administered together with haemin damages schistosomes in vitro
-
Xiao, S.; Chollet, J.; Utzinger, J.; Matile, H.; Mei, J.; Tanner, M. Artemether administered together with haemin damages schistosomes in vitro. Trans. R. Soc. Trop. Med. Hyg. 2001, 95, 67-71.
-
(2001)
Trans. R. Soc. Trop. Med. Hyg.
, vol.95
, pp. 67-71
-
-
Xiao, S.1
Chollet, J.2
Utzinger, J.3
Matile, H.4
Mei, J.5
Tanner, M.6
-
52
-
-
0031148701
-
Schistosoma mansoni: The developmental regulation and immunolocalization of antioxidant enzymes
-
Mei, H.; LoVerde, P.T. Schistosoma mansoni: The developmental regulation and immunolocalization of antioxidant enzymes. Exp. Parasitol. 1997, 86, 69-78.
-
(1997)
Exp. Parasitol.
, vol.86
, pp. 69-78
-
-
Mei, H.1
LoVerde, P.T.2
-
53
-
-
84907007344
-
Repurposing drugs for the treatment and control of helminth infections
-
Panic, G.; Duthaler, U.; Speich, B.; Keiser, J. Repurposing drugs for the treatment and control of helminth infections. Int. J. Parasitol. 2014, 4, 185-200.
-
(2014)
Int. J. Parasitol.
, vol.4
, pp. 185-200
-
-
Panic, G.1
Duthaler, U.2
Speich, B.3
Keiser, J.4
-
54
-
-
84907916642
-
New uses for old drugs: The tale of artemisinin derivatives in the elimination of schistosomiasis japonica in China
-
Liu, Y.-X.; Wu, W.; Liang, Y.-J.; Jie, Z.-L.; Wang, H.; Wang, W.; Huang, Y.-X. New uses for old drugs: The tale of artemisinin derivatives in the elimination of schistosomiasis japonica in China. Molecules 2014, 19, 15058-15074.
-
(2014)
Molecules
, vol.19
, pp. 15058-15074
-
-
Liu, Y.-X.1
Wu, W.2
Liang, Y.-J.3
Jie, Z.-L.4
Wang, H.5
Wang, W.6
Huang, Y.-X.7
-
55
-
-
0037263883
-
Randomized, double-blind, placebo-controlled trial of oral artemether for the prevention of patent Schistosoma haematobium infections
-
N'Goran, E.K.; Utzinger, J.; Gnaka, H.N.; Yapi, A.; N'Guessan, N.A.; Kigbafori, S.D.; Lengeler, C.; Chollet, J.; Shuhua, X.; Tanner, M. Randomized, double-blind, placebo-controlled trial of oral artemether for the prevention of patent Schistosoma haematobium infections. Am. J. Trop. Med. Hyg. 2003, 68, 24-32.
-
(2003)
Am. J. Trop. Med. Hyg.
, vol.68
, pp. 24-32
-
-
N'Goran, E.K.1
Utzinger, J.2
Gnaka, H.N.3
Yapi, A.4
N'Guessan, N.A.5
Kigbafori, S.D.6
Lengeler, C.7
Chollet, J.8
Shuhua, X.9
Tanner, M.10
-
56
-
-
0034656258
-
Oral artemether for prevention of Schistosoma mansoni infection: Randomised controlled trial
-
Utzinger, J.; N'Goran, E.K.; N'Dri, A.; Lengeler, C.; Xiao, S.; Tanner, M. Oral artemether for prevention of Schistosoma mansoni infection: Randomised controlled trial. Lancet 2000, 355, 1320-1325.
-
(2000)
Lancet
, vol.355
, pp. 1320-1325
-
-
Utzinger, J.1
N'Goran, E.K.2
N'Dri, A.3
Lengeler, C.4
Xiao, S.5
Tanner, M.6
-
57
-
-
77950974016
-
Efficacy and safety of mefloquine, artesunate, mefloquine-artesunate, and praziquantel against Schistosoma haematobium: Randomized, exploratory open-label trial
-
Keiser, J.; N'Guessan, N.A.; Adoubryn, K.D.; Silué, K.D.; Vounatsou, P.; Hatz, C.; Utzinger, J.; N'Goran, E.K. Efficacy and safety of mefloquine, artesunate, mefloquine-artesunate, and praziquantel against Schistosoma haematobium: Randomized, exploratory open-label trial. Clin. Infect. Dis. 2010, 50, 1205-1213.
-
(2010)
Clin. Infect. Dis.
, vol.50
, pp. 1205-1213
-
-
Keiser, J.1
N'Guessan, N.A.2
Adoubryn, K.D.3
Silué, K.D.4
Vounatsou, P.5
Hatz, C.6
Utzinger, J.7
N'Goran, E.K.8
-
58
-
-
77955923218
-
Efficacy of artesunate with sulfalene plus pyrimethamine versus praziquantel for treatment of Schistosoma mansoni in Kenyan children: An open-label randomised controlled trial
-
Obonyo, C.O.; Muok, E.M.O.; Mwinzi, P.N.M. Efficacy of artesunate with sulfalene plus pyrimethamine versus praziquantel for treatment of Schistosoma mansoni in Kenyan children: An open-label randomised controlled trial. Lancet Infect. Dis. 2010, 10, 603-611.
-
(2010)
Lancet Infect. Dis.
, vol.10
, pp. 603-611
-
-
Obonyo, C.O.1
Muok, E.M.O.2
Mwinzi, P.N.M.3
-
59
-
-
69949114110
-
Artesunate plus sulfadoxine/pyrimethamine versus praziquantel in the treatment of Schistosoma mansoni in eastern Sudan
-
Mohamed, A.A.; Mahgoub, H.M.; Magzoub, M.; Gasim, G.I.; Eldein, W.N.; Ahmed, A.A.A.; Adam, I. Artesunate plus sulfadoxine/pyrimethamine versus praziquantel in the treatment of Schistosoma mansoni in eastern Sudan. Trans. R. Soc. Trop. Med. Hyg. 2009, 103, 1062-1064.
-
(2009)
Trans. R. Soc. Trop. Med. Hyg.
, vol.103
, pp. 1062-1064
-
-
Mohamed, A.A.1
Mahgoub, H.M.2
Magzoub, M.3
Gasim, G.I.4
Eldein, W.N.5
Ahmed, A.A.A.6
Adam, I.7
-
60
-
-
80054087269
-
Efficacy of praziquantel and artemisinin derivatives for the treatment and prevention of human schistosomiasis: A systematic review and meta-analysis
-
Liu, R.; Dong, H.-F.; Guo, Y.; Zhao, Q.-P.; Jiang, M.-S. Efficacy of praziquantel and artemisinin derivatives for the treatment and prevention of human schistosomiasis: A systematic review and meta-analysis. Parasit. Vectors 2011, 4, 201.
-
(2011)
Parasit. Vectors
, vol.4
, pp. 201
-
-
Liu, R.1
Dong, H.-F.2
Guo, Y.3
Zhao, Q.-P.4
Jiang, M.-S.5
-
61
-
-
84866675899
-
Systematic review and meta-analysis of artemisinin based therapies for the treatment and prevention of schistosomiasis
-
Pérez del Villar, L.; Burguillo, F.J.; López-Abán, J.; Muro, A. Systematic review and meta-analysis of artemisinin based therapies for the treatment and prevention of schistosomiasis. PLoS One 2012, 7, e45867.
-
(2012)
PLoS One
, vol.7
, pp. e45867
-
-
Pérez Del Villar, L.1
Burguillo, F.J.2
López-Abán, J.3
Muro, A.4
-
62
-
-
84888069951
-
Malaria and artemisinin derivatives: An updated review
-
Ansari, M.T.; Saify, Z.S.; Sultana, N.; Ahmad, I.; Saeed-Ul-Hassan, S.; Tariq, I.; Khanum, M. Malaria and artemisinin derivatives: An updated review. Mini Rev. Med. Chem. 2013, 13, 1879-1902.
-
(2013)
Mini Rev. Med. Chem.
, vol.13
, pp. 1879-1902
-
-
Ansari, M.T.1
Saify, Z.S.2
Sultana, N.3
Ahmad, I.4
Saeed-Ul-Hassan, S.5
Tariq, I.6
Khanum, M.7
-
63
-
-
84875317559
-
Taxol: Efficacy against oral squamous cell carcinoma
-
Ledwitch, K.; Ogburn, R.; Cox, J.; Graham, R.; Fritzsche, A.; Gosnell, D.; Manning, T. Taxol: Efficacy against oral squamous cell carcinoma. Mini Rev. Med. Chem. 2013, 13, 509-521.
-
(2013)
Mini Rev. Med. Chem.
, vol.13
, pp. 509-521
-
-
Ledwitch, K.1
Ogburn, R.2
Cox, J.3
Graham, R.4
Fritzsche, A.5
Gosnell, D.6
Manning, T.7
-
64
-
-
84868685907
-
Terpenoids: Natural products for cancer therapy
-
Huang, M.; Lu, J.-J.; Huang, M.-Q.; Bao, J.-L.; Chen, X.-P.; Wang, Y.-T. Terpenoids: Natural products for cancer therapy. Expert Opin. Investig. Drugs 2012, 21, 1801-1818.
-
(2012)
Expert Opin. Investig. Drugs
, vol.21
, pp. 1801-1818
-
-
Huang, M.1
Lu, J.-J.2
Huang, M.-Q.3
Bao, J.-L.4
Chen, X.-P.5
Wang, Y.-T.6
-
65
-
-
84874940295
-
Anthelmintic activity of the natural compound (+)-limonene epoxide against Schistosoma mansoni
-
De Moraes, J.; Almeida, A.A.C.; Brito, M.R.M.; Marques, T.H.C.; Lima, T.C.; de Sousa, D.P.; Nakano, E.; Mendonça, R.Z.; Freitas, R.M. Anthelmintic activity of the natural compound (+)-limonene epoxide against Schistosoma mansoni . Planta Med. 2013, 79, 253-258.
-
(2013)
Planta Med.
, vol.79
, pp. 253-258
-
-
De Moraes, J.1
Almeida, A.A.C.2
Brito, M.R.M.3
Marques, T.H.C.4
Lima, T.C.5
De Sousa, D.P.6
Nakano, E.7
Mendonça, R.Z.8
Freitas, R.M.9
-
66
-
-
84865338100
-
Fungal transformation and schistosomicidal effects of pimaradienoic acid
-
Porto, T.S.; da Silva Filho, A.A.; Magalhães, L.G.; dos Santos, R.A.; Furtado, N.A.J.C.; Arakawa, N.S.; Said, S.; de Oliveira, D.C.R.; Gregório, L.E.; Rodrigues, V.; et al. Fungal transformation and schistosomicidal effects of pimaradienoic acid. Chem. Biodivers. 2012, 9, 1465-1474.
-
(2012)
Chem. Biodivers.
, vol.9
, pp. 1465-1474
-
-
Porto, T.S.1
Da Silva Filho, A.A.2
Magalhães, L.G.3
Dos Santos, R.A.4
Furtado, N.A.J.C.5
Arakawa, N.S.6
Said, S.7
De Oliveira, D.C.R.8
Gregório, L.E.9
Rodrigues, V.10
-
67
-
-
0035726697
-
African ethnobotany and healthcare: Emphasis on mozambique
-
Bandeira, S.O.; Gaspar, F.; Pagula, F.P. African ethnobotany and healthcare: Emphasis on mozambique. Pharm. Biol. 2001, 39 (Suppl. S1), 70-73.
-
(2001)
Pharm. Biol.
, vol.39
, pp. 70-73
-
-
Bandeira, S.O.1
Gaspar, F.2
Pagula, F.P.3
-
68
-
-
84871621180
-
In vitro schistosomicidal activity of balsaminol F and karavilagenin C
-
Ramalhete, C.; Magalhães, L.G.; Rodrigues, V.; Mulhovo, S.; Da Silva Filho, A.A.; Ferreira, M.-J.U. In vitro schistosomicidal activity of balsaminol F and karavilagenin C. Planta Med. 2012, 78, 1912-1917.
-
(2012)
Planta Med.
, vol.78
, pp. 1912-1917
-
-
Ramalhete, C.1
Magalhães, L.G.2
Rodrigues, V.3
Mulhovo, S.4
Da Silva Filho, A.A.5
Ferreira, M.-J.U.6
-
69
-
-
78650740963
-
Karavilagenin C derivatives as antimalarials
-
Ramalhete, C.; Lopes, D.; Molnár, J.; Mulhovo, S.; Rosário, V.E.; Ferreira, M.-J.U. Karavilagenin C derivatives as antimalarials. Bioorg. Med. Chem. 2011, 19, 330-338.
-
(2011)
Bioorg. Med. Chem.
, vol.19
, pp. 330-338
-
-
Ramalhete, C.1
Lopes, D.2
Molnár, J.3
Mulhovo, S.4
Rosário, V.E.5
Ferreira, M.-J.U.6
-
70
-
-
82255192175
-
Triterpenoids as inhibitors of erythrocytic and liver stages of Plasmodium infections
-
Ramalhete, C.; da Cruz, F.P.; Lopes, D.; Mulhovo, S.; Rosário, V.E.; Prudêncio, M.; Ferreira, M.-J.U. Triterpenoids as inhibitors of erythrocytic and liver stages of Plasmodium infections. Bioorg. Med. Chem. 2011, 19, 7474-7481.
-
(2011)
Bioorg. Med. Chem.
, vol.19
, pp. 7474-7481
-
-
Ramalhete, C.1
Da Cruz, F.P.2
Lopes, D.3
Mulhovo, S.4
Rosário, V.E.5
Prudêncio, M.6
Ferreira, M.-J.U.7
-
71
-
-
84867504178
-
Activity of compounds isolated from Baccharis dracunculifolia D.C. (Asteraceae) against Paracoccidioides brasiliensis
-
Johann, S.; Oliveira, F.B.; Siqueira, E.P.; Cisalpino, P.S.; Rosa, C.A.; Alves, T.M.A.; Zani, C.L.; Cota, B.B. Activity of compounds isolated from Baccharis dracunculifolia D.C. (Asteraceae) against Paracoccidioides brasiliensis. Med. Mycol. 2012, 50, 843-851.
-
(2012)
Med. Mycol.
, vol.50
, pp. 843-851
-
-
Johann, S.1
Oliveira, F.B.2
Siqueira, E.P.3
Cisalpino, P.S.4
Rosa, C.A.5
Alves, T.M.A.6
Zani, C.L.7
Cota, B.B.8
-
72
-
-
84897014954
-
Antischistosomal activity of the terpene nerolidol
-
Silva, M.P.N.; Oliveira, G.L.S.; de Carvalho, R.B.F.; de Sousa, D.P.; Freitas, R.M.; Pinto, P.L.S.; de Moraes, J. Antischistosomal activity of the terpene nerolidol. Molecules 2014, 19, 3793-3803.
-
(2014)
Molecules
, vol.19
, pp. 3793-3803
-
-
Silva, M.P.N.1
Oliveira, G.L.S.2
De Carvalho, R.B.F.3
De Sousa, D.P.4
Freitas, R.M.5
Pinto, P.L.S.6
De Moraes, J.7
-
73
-
-
0031129409
-
Effects of goyazensolide during in vitro cultivation of Schistosoma mansoni
-
Barth, L.R.; Fernandes, A.P.M.; Ribeiro-Paes, J.T.; Rodrigues, V. Effects of Goyazensolide during in Vitro Cultivation of Schistosoma mansoni . Mem. Inst. Oswaldo Cruz 1997, 92, 427-429.
-
(1997)
Mem. Inst. Oswaldo Cruz
, vol.92
, pp. 427-429
-
-
Barth, L.R.1
Fernandes, A.P.M.2
Ribeiro-Paes, J.T.3
Rodrigues, V.4
-
74
-
-
0026858425
-
Antischistosomal activities of sesquiterpene lactones and steroid glucosides from Vernonia amygdalina, possibly used by wild chimpanzees against parasite-related diseases
-
Jisaka, M.; Kawanaka, M.; Sugiyama, H.; Takegawa, K.; Huffman, M.A.; Ohigashi, H.; Koshimizu, K. Antischistosomal activities of sesquiterpene lactones and steroid glucosides from Vernonia amygdalina, possibly used by wild chimpanzees against parasite-related diseases. Biosci. Biotechnol. Biochem. 1992, 56, 845-846.
-
(1992)
Biosci. Biotechnol. Biochem.
, vol.56
, pp. 845-846
-
-
Jisaka, M.1
Kawanaka, M.2
Sugiyama, H.3
Takegawa, K.4
Huffman, M.A.5
Ohigashi, H.6
Koshimizu, K.7
-
75
-
-
67650789618
-
The genome of the blood fluke Schistosoma mansoni
-
Berriman, M.; Haas, B.J.; LoVerde, P.T.; Wilson, R.A.; Dillon, G.P.; Cerqueira, G.C.; Mashiyama, S.T.; Al-Lazikani, B.; Andrade, L.F.; Ashton, P.D.; et al . The genome of the blood fluke Schistosoma mansoni. Nature 2009, 460, 352-358.
-
(2009)
Nature
, vol.460
, pp. 352-358
-
-
Berriman, M.1
Haas, B.J.2
LoVerde, P.T.3
Wilson, R.A.4
Dillon, G.P.5
Cerqueira, G.C.6
Mashiyama, S.T.7
Al-Lazikani, B.8
Andrade, L.F.9
Ashton, P.D.10
-
76
-
-
67650786530
-
The Schistosoma japonicum genome reveals features of host-parasite interplay
-
Consortium, F.A. The Schistosoma japonicum genome reveals features of host-parasite interplay. Nature 2009, 460, 345-351.
-
(2009)
Nature
, vol.460
, pp. 345-351
-
-
Consortium, F.A.1
-
77
-
-
84859970281
-
Identification of thioredoxin glutathione reductase inhibitors that kill cestode and trematode parasites
-
Ross, F.; Hernández, P.; Porcal, W.; López, G.V.; Cerecetto, H.; González, M.; Basika, T.; Carmona, C.; Fló, M.; Maggioli, G.; et al. Identification of thioredoxin glutathione reductase inhibitors that kill cestode and trematode parasites. PLoS One 2012, 7, e35033.
-
(2012)
PLoS One
, vol.7
, pp. e35033
-
-
Ross, F.1
Hernández, P.2
Porcal, W.3
López, G.V.4
Cerecetto, H.5
González, M.6
Basika, T.7
Carmona, C.8
Fló, M.9
Maggioli, G.10
-
78
-
-
84867513471
-
Protein kinases as potential targets for novel anti-schistosomal strategies
-
Beckmann, S.; Leutner, S.; Gouignard, N.; Dissous, C.; Grevelding, C.G. Protein kinases as potential targets for novel anti-schistosomal strategies. Curr. Pharm. Des. 2012, 18, 3579-3594.
-
(2012)
Curr. Pharm. Des.
, vol.18
, pp. 3579-3594
-
-
Beckmann, S.1
Leutner, S.2
Gouignard, N.3
Dissous, C.4
Grevelding, C.G.5
-
79
-
-
79957980956
-
Characterization of the phytochelatin synthase of Schistosoma mansoni
-
Ray, D.; Williams, D.L. Characterization of the phytochelatin synthase of Schistosoma mansoni . PLoS Negl. Trop. Dis. 2011, 5, e1168.
-
(2011)
PLoS Negl. Trop. Dis.
, vol.5
, pp. e1168
-
-
Ray, D.1
Williams, D.L.2
-
80
-
-
84887458904
-
Characterization of potential drug targets farnesyl diphosphate synthase and geranylgeranyl diphosphate synthase in Schistosoma mansoni
-
Ziniel, P.D.; Desai, J.; Cass, C.L.; Gatto, C.; Oldfield, E.; Williams, D.L. Characterization of potential drug targets farnesyl diphosphate synthase and geranylgeranyl diphosphate synthase in Schistosoma mansoni. Antimicrob. Agents Chemother. 2013, 57, 5969-5976.
-
(2013)
Antimicrob. Agents Chemother.
, vol.57
, pp. 5969-5976
-
-
Ziniel, P.D.1
Desai, J.2
Cass, C.L.3
Gatto, C.4
Oldfield, E.5
Williams, D.L.6
-
81
-
-
84884697264
-
Schistosoma mansoni Sirtuins: Characterization and potential as chemotherapeutic targets
-
Lancelot, J.; Caby, S.; Dubois-Abdesselem, F.; Vanderstraete, M.; Trolet, J.; Oliveira, G.; Bracher, F.; Jung, M.; Pierce, R.J. Schistosoma mansoni Sirtuins: Characterization and potential as chemotherapeutic targets. PLoS Negl. Trop. Dis. 2013, 7, e2428.
-
(2013)
PLoS Negl. Trop. Dis.
, vol.7
, pp. e2428
-
-
Lancelot, J.1
Caby, S.2
Dubois-Abdesselem, F.3
Vanderstraete, M.4
Trolet, J.5
Oliveira, G.6
Bracher, F.7
Jung, M.8
Pierce, R.J.9
-
82
-
-
84866004507
-
Pharmacological actions and therapeutic applications of Salvia miltiorrhiza depside salt and its active components
-
Wu, W.; Wang, Y. Pharmacological actions and therapeutic applications of Salvia miltiorrhiza depside salt and its active components. Acta Pharmacol. Sin. 2012, 33, 1119-1130.
-
(2012)
Acta Pharmacol. Sin.
, vol.33
, pp. 1119-1130
-
-
Wu, W.1
Wang, Y.2
-
83
-
-
27844511101
-
Danshen: An overview of its chemistry, pharmacology, pharmacokinetics, and clinical use
-
Zhou, L.; Zuo, Z.; Chow, M.S.S. Danshen: An overview of its chemistry, pharmacology, pharmacokinetics, and clinical use. J. Clin. Pharmacol. 2005, 45, 1345-1359.
-
(2005)
J. Clin. Pharmacol.
, vol.45
, pp. 1345-1359
-
-
Zhou, L.1
Zuo, Z.2
Chow, M.S.S.3
-
84
-
-
51849152384
-
A 1,536-well-based kinetic HTS assay for inhibitors of Schistosoma mansoni thioredoxin glutathione reductase
-
Lea, W.A.; Jadhav, A.; Rai, G.; Sayed, A.A.; Cass, C.L.; Inglese, J.; Williams, D.L.; Austin, C.P.; Simeonov, A. A 1,536-well-based kinetic HTS assay for inhibitors of Schistosoma mansoni thioredoxin glutathione reductase. Assay Drug Dev. Technol. 2008, 6, 551-555.
-
(2008)
Assay Drug Dev. Technol.
, vol.6
, pp. 551-555
-
-
Lea, W.A.1
Jadhav, A.2
Rai, G.3
Sayed, A.A.4
Cass, C.L.5
Inglese, J.6
Williams, D.L.7
Austin, C.P.8
Simeonov, A.9
-
85
-
-
84881434938
-
Thioredoxin glutathione reductase-dependent redox networks in platyhelminth parasites
-
Williams, D.L.; Bonilla, M.; Gladyshev, V.N.; Salinas, G. Thioredoxin glutathione reductase-dependent redox networks in platyhelminth parasites. Antioxid. Redox Signal. 2013, 19, 735-745.
-
(2013)
Antioxid. Redox Signal.
, vol.19
, pp. 735-745
-
-
Williams, D.L.1
Bonilla, M.2
Gladyshev, V.N.3
Salinas, G.4
-
86
-
-
34347264532
-
Thioredoxin glutathione reductase from Schistosoma mansoni: An essential parasite enzyme and a key drug target
-
Kuntz, A.N.; Davioud-Charvet, E.; Sayed, A.A.; Califf, L.L.; Dessolin, J.; Arnér, E.S.J.; Williams, D.L. Thioredoxin glutathione reductase from Schistosoma mansoni: An essential parasite enzyme and a key drug target. PLoS Med. 2007, 4, e206.
-
(2007)
PLoS Med.
, vol.4
, pp. e206
-
-
Kuntz, A.N.1
Davioud-Charvet, E.2
Sayed, A.A.3
Califf, L.L.4
Dessolin, J.5
Arnér, E.S.J.6
Williams, D.L.7
-
87
-
-
79953135337
-
Linked thioredoxin-glutathione systems in platyhelminth parasites: Alternative pathways for glutathione reduction and deglutathionylation
-
Bonilla, M.; Denicola, A.; Marino, S.M.; Gladyshev, V.N.; Salinas, G. Linked thioredoxin-glutathione systems in platyhelminth parasites: Alternative pathways for glutathione reduction and deglutathionylation. J. Biol. Chem. 2011, 286, 4959-4967.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 4959-4967
-
-
Bonilla, M.1
Denicola, A.2
Marino, S.M.3
Gladyshev, V.N.4
Salinas, G.5
-
88
-
-
84860524458
-
Activity of epiisopiloturine against Schistosoma mansoni
-
Veras, L.M.; Guimaraes, M.A.; Campelo, Y.D.; Vieira, M.M.; Nascimento, C.; Lima, D.F.; Vasconcelos, L.; Nakano, E.; Kuckelhaus, S.S.; Batista, M.C.; et al. Activity of epiisopiloturine against Schistosoma mansoni. Curr. Med. Chem. 2012, 19, 2051-2058.
-
(2012)
Curr. Med. Chem.
, vol.19
, pp. 2051-2058
-
-
Veras, L.M.1
Guimaraes, M.A.2
Campelo, Y.D.3
Vieira, M.M.4
Nascimento, C.5
Lima, D.F.6
Vasconcelos, L.7
Nakano, E.8
Kuckelhaus, S.S.9
Batista, M.C.10
-
89
-
-
78751491557
-
Schistosoma mansoni: In vitro schistosomicidal activity of piplartine
-
De Moraes, J.; Nascimento, C.; Lopes, P.O.M.V.; Nakano, E.; Yamaguchi, L.F.; Kato, M.J.; Kawano, T. Schistosoma mansoni : In vitro schistosomicidal activity of piplartine. Exp. Parasitol. 2011, 127, 357-364.
-
(2011)
Exp. Parasitol.
, vol.127
, pp. 357-364
-
-
De Moraes, J.1
Nascimento, C.2
Lopes, P.O.M.V.3
Nakano, E.4
Yamaguchi, L.F.5
Kato, M.J.6
Kawano, T.7
-
90
-
-
84895541950
-
A penta-substituted pyridine alkaloid from the rhizome of Jatropha elliptica (Pohl) Muell. Arg. Is active against Schistosoma mansoni and Biomphalaria glabrata
-
Dos Santos, A.F.; Fonseca, S.A.; César, F.A.; de Azevedo Albuquerque, M.C.P.; Santana, J.V.; Santana, A.E.G. A penta-substituted pyridine alkaloid from the rhizome of Jatropha elliptica (Pohl) Muell. Arg. is active against Schistosoma mansoni and Biomphalaria glabrata. Parasitol. Res. 2014, 113, 1077-1084.
-
(2014)
Parasitol. Res.
, vol.113
, pp. 1077-1084
-
-
Dos Santos, A.F.1
Fonseca, S.A.2
César, F.A.3
De Azevedo Albuquerque, M.C.P.4
Santana, J.V.5
Santana, A.E.G.6
-
91
-
-
84879659491
-
Antischistosomal activity of a calcium channel antagonist on schistosomula and adult Schistosoma mansoni worms
-
Silva-Moraes, V.; Couto, F.F.B.; Vasconcelos, M.M.; Araújo, N.; Coelho, P.M.Z.; Katz, N.; Grenfell, R.F.Q.; Fernanda, F.; Couto, B.; Marcos, P.; et al. Antischistosomal activity of a calcium channel antagonist on schistosomula and adult Schistosoma mansoni worms. Mem. Inst. Oswaldo Cruz 2013, 108, 600-604.
-
(2013)
Mem. Inst. Oswaldo Cruz
, vol.108
, pp. 600-604
-
-
Silva-Moraes, V.1
Couto, F.F.B.2
Vasconcelos, M.M.3
Araújo, N.4
Coelho, P.M.Z.5
Katz, N.6
Grenfell, R.F.Q.7
Fernanda, F.8
Couto, B.9
Marcos, P.10
-
92
-
-
84862774712
-
Evaluation of the schistosomicidal activity of the steroidal alkaloids from Solanum lycocarpum fruits
-
Miranda, M.A.; Magalhães, L.G.; Tiossi, R.F.J.; Kuehn, C.C.; Oliveira, L.G.R.; Rodrigues, V.; McChesney, J.D.; Bastos, J.K. Evaluation of the schistosomicidal activity of the steroidal alkaloids from Solanum lycocarpum fruits. Parasitol. Res. 2012, 111, 257-262.
-
(2012)
Parasitol. Res.
, vol.111
, pp. 257-262
-
-
Miranda, M.A.1
Magalhães, L.G.2
Tiossi, R.F.J.3
Kuehn, C.C.4
Oliveira, L.G.R.5
Rodrigues, V.6
McChesney, J.D.7
Bastos, J.K.8
-
93
-
-
84872405303
-
Identification of plumbagin and sanguinarine as effective chemotherapeutic agents for treatment of schistosomiasis
-
Zhang, S.-M.; Coultas, K. Identification of plumbagin and sanguinarine as effective chemotherapeutic agents for treatment of schistosomiasis. Int. J. Parasitol. Drugs Drug Resist. 2013, 3, 28-34.
-
(2013)
Int. J. Parasitol. Drugs Drug Resist.
, vol.3
, pp. 28-34
-
-
Zhang, S.-M.1
Coultas, K.2
-
94
-
-
70449558126
-
Interference with hemozoin formation represents an important mechanism of schistosomicidal action of antimalarial quinoline methanols
-
Corrêa Soares, J.B.R.; Menezes, D.; Vannier-Santos, M.A.; Ferreira-Pereira, A.; Almeida, G.T.; Venancio, T.M.; Verjovski-Almeida, S.; Zishiri, V.K.; Kuter, D.; Hunter, R.; et al . Interference with hemozoin formation represents an important mechanism of schistosomicidal action of antimalarial quinoline methanols. PLoS Negl. Trop. Dis. 2009, 3, e477.
-
(2009)
PLoS Negl. Trop. Dis.
, vol.3
, pp. e477
-
-
Corrêa Soares, J.B.R.1
Menezes, D.2
Vannier-Santos, M.A.3
Ferreira-Pereira, A.4
Almeida, G.T.5
Venancio, T.M.6
Verjovski-Almeida, S.7
Zishiri, V.K.8
Kuter, D.9
Hunter, R.10
-
95
-
-
0033763909
-
Haemozoin in Schistosoma mansoni
-
Oliveira, M.F.; D'Avila, J.C.P.; Torres, C.R.; Oliveira, P.L.; Tempone, A.J.; Rumjanek, F.D.; Braga, C.M.S.; Silva, J.R.; Dansa-Petretski, M.; Oliveira, M.A.; et al. Haemozoin in Schistosoma mansoni . Mol. Biochem. Parasitol. 2000, 111, 217-221.
-
(2000)
Mol. Biochem. Parasitol.
, vol.111
, pp. 217-221
-
-
Oliveira, M.F.1
D'Avila, J.C.P.2
Torres, C.R.3
Oliveira, P.L.4
Tempone, A.J.5
Rumjanek, F.D.6
Braga, C.M.S.7
Silva, J.R.8
Dansa-Petretski, M.9
Oliveira, M.A.10
-
96
-
-
18244373745
-
On the pro-oxidant effects of haemozoin
-
Oliveira, M.F.; Timm, B.L.; Machado, E.A.; Miranda, K.; Attias, M.; Silva, J.R.; Dansa-Petretski, M.; de Oliveira, M.A.; de Souza, W.; Pinhal, N.M.; et al. On the pro-oxidant effects of haemozoin. FEBS Lett. 2002, 512, 139-144.
-
(2002)
FEBS Lett.
, vol.512
, pp. 139-144
-
-
Oliveira, M.F.1
Timm, B.L.2
Machado, E.A.3
Miranda, K.4
Attias, M.5
Silva, J.R.6
Dansa-Petretski, M.7
De Oliveira, M.A.8
De Souza, W.9
Pinhal, N.M.10
-
97
-
-
65549102140
-
Mefloquine-An aminoalcohol with promising antischistosomal properties in mice
-
Keiser, J.; Chollet, J.; Xiao, S.-H.; Mei, J.-Y.; Jiao, P.-Y.; Utzinger, J.; Tanner, M. Mefloquine-An aminoalcohol with promising antischistosomal properties in mice. PLoS Negl. Trop. Dis. 2009, 3, e350.
-
(2009)
PLoS Negl. Trop. Dis.
, vol.3
, pp. e350
-
-
Keiser, J.1
Chollet, J.2
Xiao, S.-H.3
Mei, J.-Y.4
Jiao, P.-Y.5
Utzinger, J.6
Tanner, M.7
-
98
-
-
75149183510
-
Morphological effects and tegumental alterations induced by mefloquine on schistosomula and adult flukes of Schistosoma mansoni
-
Manneck, T.; Haggenmüller, Y.; Keiser, J. Morphological effects and tegumental alterations induced by mefloquine on schistosomula and adult flukes of Schistosoma mansoni. Parasitology 2010, 137, 85-98.
-
(2010)
Parasitology
, vol.137
, pp. 85-98
-
-
Manneck, T.1
Haggenmüller, Y.2
Keiser, J.3
-
99
-
-
78049263263
-
Schistosoma mansoni: Antischistosomal activity of the four optical isomers and the two racemates of mefloquine on schistosomula and adult worms in vitro and in vivo
-
Manneck, T.; Braissant, O.; Ellis, W.; Keiser, J. Schistosoma mansoni : Antischistosomal activity of the four optical isomers and the two racemates of mefloquine on schistosomula and adult worms in vitro and in vivo. Exp. Parasitol. 2011, 127, 260-269.
-
(2011)
Exp. Parasitol.
, vol.127
, pp. 260-269
-
-
Manneck, T.1
Braissant, O.2
Ellis, W.3
Keiser, J.4
-
100
-
-
84861148384
-
Antischistosomal activities of mefloquine-related arylmethanols
-
Ingram, K.; Ellis, W.; Keiser, J. Antischistosomal activities of mefloquine-related arylmethanols. Antimicrob. Agents Chemother. 2012, 56, 3207-3215.
-
(2012)
Antimicrob. Agents Chemother.
, vol.56
, pp. 3207-3215
-
-
Ingram, K.1
Ellis, W.2
Keiser, J.3
-
101
-
-
79960444155
-
Interactions of mefloquine with praziquantel in the Schistosoma mansoni mouse model and in vitro
-
Keiser, J.; Manneck, T.; Vargas, M. Interactions of mefloquine with praziquantel in the Schistosoma mansoni mouse model and in vitro. J. Antimicrob. Chemother. 2011, 66, 1791-1797.
-
(2011)
J. Antimicrob. Chemother.
, vol.66
, pp. 1791-1797
-
-
Keiser, J.1
Manneck, T.2
Vargas, M.3
-
102
-
-
84911869289
-
Flavonoids as Important Molecules of Plant Interactions with the Environment
-
Mierziak, J.; Kostyn, K.; Kulma, A. Flavonoids as Important Molecules of Plant Interactions with the Environment. Molecules 2014, 19, 16240-16265.
-
(2014)
Molecules
, vol.19
, pp. 16240-16265
-
-
Mierziak, J.1
Kostyn, K.2
Kulma, A.3
-
103
-
-
73949104134
-
Flavonoids: New roles for old molecules
-
Buer, C.S.; Imin, N.; Djordjevic, M.A. Flavonoids: New roles for old molecules. J. Integr. Plant Biol. 2010, 52, 98-111.
-
(2010)
J. Integr. Plant Biol.
, vol.52
, pp. 98-111
-
-
Buer, C.S.1
Imin, N.2
Djordjevic, M.A.3
-
104
-
-
84887064917
-
Flavonoids as prospective compounds for anti-cancer therapy
-
Ravishankar, D.; Rajora, A.K.; Greco, F.; Osborn, H.M.I. Flavonoids as prospective compounds for anti-cancer therapy. Int. J. Biochem. Cell Biol. 2013, 45, 2821-2831.
-
(2013)
Int. J. Biochem. Cell Biol.
, vol.45
, pp. 2821-2831
-
-
Ravishankar, D.1
Rajora, A.K.2
Greco, F.3
Osborn, H.M.I.4
-
105
-
-
84879335548
-
Polyphenols: Multipotent therapeutic agents in neurodegenerative diseases
-
Bhullar, K.S.; Rupasinghe, H.P.V. Polyphenols: Multipotent therapeutic agents in neurodegenerative diseases. Oxid. Med. Cell. Longev. 2013, 2013, doi:10.1155/2013/891748.
-
(2013)
Oxid. Med. Cell. Longev.
, vol.2013
-
-
Bhullar, K.S.1
Rupasinghe, H.P.V.2
-
106
-
-
84872855976
-
Dietary flavonoids and the development of type 2 diabetes and cardiovascular diseases: Review of recent findings
-
Van Dam, R.M.; Naidoo, N.; Landberg, R. Dietary flavonoids and the development of type 2 diabetes and cardiovascular diseases: Review of recent findings. Curr. Opin. Lipidol. 2013, 24, 25-33.
-
(2013)
Curr. Opin. Lipidol.
, vol.24
, pp. 25-33
-
-
Van Dam, R.M.1
Naidoo, N.2
Landberg, R.3
-
107
-
-
0036194878
-
Antischistosomal bioactivity of isoflavonoids from Millettia thonningii (Leguminosae)
-
Lyddiard, J.R.A.; Whitfield, P.J.; Bartlett, A. Antischistosomal bioactivity of isoflavonoids from Millettia thonningii (Leguminosae). J. Parasitol. 2002, 88, 163-170.
-
(2002)
J. Parasitol.
, vol.88
, pp. 163-170
-
-
Lyddiard, J.R.A.1
Whitfield, P.J.2
Bartlett, A.3
-
108
-
-
84866118859
-
In vitro schistosomicidal activity of some brazilian cerrado species and their isolated compounds
-
Cunha, N.L.; Uchôa, C.J.D.M.; Cintra, L.S.; de Souza, H.C.; Peixoto, J.A.; Silva, C.P.; Magalhães, L.G.; Gimenez, V.M.M.; Groppo, M.; Rodrigues, V.; et al. In vitro schistosomicidal activity of some brazilian cerrado species and their isolated compounds. Evid. Based. Complement. Altern. Med. 2012, 2012, 173614.
-
(2012)
Evid. Based. Complement. Altern. Med.
, vol.2012
, pp. 173614
-
-
Cunha, N.L.1
Uchôa, C.J.D.M.2
Cintra, L.S.3
De Souza, H.C.4
Peixoto, J.A.5
Silva, C.P.6
Magalhães, L.G.7
Gimenez, V.M.M.8
Groppo, M.9
Rodrigues, V.10
-
109
-
-
84862021806
-
Schistosomicidal evaluation of flavonoids from two species of Styrax against Schistosoma mansoni adult worms
-
Braguine, C.G.; Bertanha, C.S.; Gonçalves, U.O.; Magalhães, L.G.; Rodrigues, V.; Melleiro Gimenez, V.M.; Groppo, M.; Silva, M.L.A.E.; Cunha, W.R.; Januário, A.H.; et al. Schistosomicidal evaluation of flavonoids from two species of Styrax against Schistosoma mansoni adult worms. Pharm. Biol. 2012, 50, 925-929.
-
(2012)
Pharm. Biol.
, vol.50
, pp. 925-929
-
-
Braguine, C.G.1
Bertanha, C.S.2
Gonçalves, U.O.3
Magalhães, L.G.4
Rodrigues, V.5
Melleiro Gimenez, V.M.6
Groppo, M.7
Silva, M.L.A.E.8
Cunha, W.R.9
Januário, A.H.10
-
110
-
-
78449249121
-
Identification by high-throughput screening of inhibitors of Schistosoma mansoni NAD(+) catabolizing enzyme
-
Kuhn, I.; Kellenberger, E.; Said-Hassane, F.; Villa, P.; Rognan, D.; Lobstein, A.; Haiech, J.; Hibert, M.; Schuber, F.; Muller-Steffner, H. Identification by high-throughput screening of inhibitors of Schistosoma mansoni NAD(+) catabolizing enzyme. Bioorg. Med. Chem. 2010, 18, 7900-7910.
-
(2010)
Bioorg. Med. Chem.
, vol.18
, pp. 7900-7910
-
-
Kuhn, I.1
Kellenberger, E.2
Said-Hassane, F.3
Villa, P.4
Rognan, D.5
Lobstein, A.6
Haiech, J.7
Hibert, M.8
Schuber, F.9
Muller-Steffner, H.10
-
111
-
-
79955024095
-
Enzymatic hydrolysis and extraction of arachidonic acid rich lipids from Mortierella alpina
-
You, J.-Y.; Peng, C.; Liu, X.; Ji, X.-J.; Lu, J.; Tong, Q.; Wei, P.; Cong, L.; Li, Z.; Huang, H. Enzymatic hydrolysis and extraction of arachidonic acid rich lipids from Mortierella alpina. Bioresour. Technol. 2011, 102, 6088-6094.
-
(2011)
Bioresour. Technol.
, vol.102
, pp. 6088-6094
-
-
You, J.-Y.1
Peng, C.2
Liu, X.3
Ji, X.-J.4
Lu, J.5
Tong, Q.6
Wei, P.7
Cong, L.8
Li, Z.9
Huang, H.10
-
112
-
-
84871760704
-
Development of a defined medium for arachidonic acid production by Mortierella alpina using a visualization method
-
Liu, X.; Ji, X.; Zhang, H.; Fu, N.; Yan, L.; Deng, Z.; Huang, H. Development of a defined medium for arachidonic acid production by Mortierella alpina using a visualization method. Appl. Biochem. Biotechnol. 2012, 168, 1516-527.
-
(2012)
Appl. Biochem. Biotechnol.
, vol.168
, pp. 1516-1527
-
-
Liu, X.1
Ji, X.2
Zhang, H.3
Fu, N.4
Yan, L.5
Deng, Z.6
Huang, H.7
-
113
-
-
84898545025
-
Fungal arachidonic acid-rich oil: Research, development and industrialization
-
Ji, X.-J.; Ren, L.-J.; Nie, Z.-K.; Huang, H.; Ouyang, P.-K. Fungal arachidonic acid-rich oil: Research, development and industrialization. Crit. Rev. Biotechnol. 2014, 34, 197-214.
-
(2014)
Crit. Rev. Biotechnol.
, vol.34
, pp. 197-214
-
-
Ji, X.-J.1
Ren, L.-J.2
Nie, Z.-K.3
Huang, H.4
Ouyang, P.-K.5
-
114
-
-
77955383443
-
In vitro and in vivo activities of arachidonic acid against Schistosoma mansoni and Schistosoma haematobium
-
El Ridi, R.; Aboueldahab, M.; Tallima, H.; Salah, M.; Mahana, N.; Fawzi, S.; Mohamed, S.H.; Fahmy, O.M. In vitro and in vivo activities of arachidonic acid against Schistosoma mansoni and Schistosoma haematobium . Antimicrob. Agents Chemother. 2010, 54, 3383-3389.
-
(2010)
Antimicrob. Agents Chemother.
, vol.54
, pp. 3383-3389
-
-
El Ridi, R.1
Aboueldahab, M.2
Tallima, H.3
Salah, M.4
Mahana, N.5
Fawzi, S.6
Mohamed, S.H.7
Fahmy, O.M.8
-
115
-
-
28444475157
-
In vitro and in vivo effects of unsaturated fatty acids on Schistosoma mansoni and S. Haematobium lung-stage larvae
-
Tallima, H.; Salah, M.; El-Ridi, R. In vitro and in vivo effects of unsaturated fatty acids on Schistosoma mansoni and S. haematobium lung-stage larvae. J. Parasitol. 2005, 91, 1094-1102.
-
(2005)
J. Parasitol.
, vol.91
, pp. 1094-1102
-
-
Tallima, H.1
Salah, M.2
El-Ridi, R.3
-
116
-
-
33748921363
-
Equilibrium in lung schistosomula sphingomyelin breakdown and biosynthesis allows very small molecules, but not antibody, to access proteins at the host-parasite interface
-
El Ridi, R.; Tallima, H. Equilibrium in lung schistosomula sphingomyelin breakdown and biosynthesis allows very small molecules, but not antibody, to access proteins at the host-parasite interface. J. Parasitol. 2006, 92, 730-737.
-
(2006)
J. Parasitol.
, vol.92
, pp. 730-737
-
-
El Ridi, R.1
Tallima, H.2
-
118
-
-
84860678568
-
The potential of secondary metabolites from plants as drugs or leads against protozoan neglected diseases-Part II
-
Schmidt, T.J.; Khalid, S.A.; Romanha, A.J.; Alves, T.M.; Biavatti, M.W.; Brun, R.; da Costa, F.B.; de Castro, S.L.; Ferreira, V.F.; de Lacerda, M.V.G.; et al. The potential of secondary metabolites from plants as drugs or leads against protozoan neglected diseases-Part II. Curr. Med. Chem. 2012, 19, 2176-2228.
-
(2012)
Curr. Med. Chem.
, vol.19
, pp. 2176-2228
-
-
Schmidt, T.J.1
Khalid, S.A.2
Romanha, A.J.3
Alves, T.M.4
Biavatti, M.W.5
Brun, R.6
Da Costa, F.B.7
De Castro, S.L.8
Ferreira, V.F.9
De Lacerda, M.V.G.10
-
119
-
-
0014361067
-
Antimicrobial substances of superior plants. XXVII. Isolation of plumbagin from Plumbago scandens L
-
De Lima, O.G.; d'Albuquerque, I.L.; Maciel, G.M.; Maciel, M.C. Antimicrobial substances of superior plants. XXVII. Isolation of plumbagin from Plumbago scandens L. Rev. Inst. Antibiot. (Recife) 1968, 8, 95-97.
-
(1968)
Rev. Inst. Antibiot. (Recife)
, vol.8
, pp. 95-97
-
-
De Lima, O.G.1
D'Albuquerque, I.L.2
Maciel, G.M.3
Maciel, M.C.4
-
120
-
-
0037078250
-
Kwanzoquinones A-G and other constituents of Hemerocallis fulva "Kwanzo" roots and their activity against the human pathogenic trematode Schistosoma mansoni
-
Cichewicz, R.H.; Lim, K.-C.; McKerrow, J.H.; Nair, M.G. Kwanzoquinones A-G and other constituents of Hemerocallis fulva "Kwanzo" roots and their activity against the human pathogenic trematode Schistosoma mansoni . Tetrahedron 2002, 58, 8597-8606.
-
(2002)
Tetrahedron
, vol.58
, pp. 8597-8606
-
-
Cichewicz, R.H.1
Lim, K.-C.2
McKerrow, J.H.3
Nair, M.G.4
-
121
-
-
77949316049
-
In vitro schistosomicidal effects of some phloroglucinol derivatives from Dryopteris species against Schistosoma mansoni adult worms
-
Magalhães, L.G.; Kapadia, G.J.; da Silva Tonuci, L.R.; Caixeta, S.C.; Parreira, N.A.; Rodrigues, V.; Da Silva Filho, A.A. In vitro schistosomicidal effects of some phloroglucinol derivatives from Dryopteris species against Schistosoma mansoni adult worms. Parasitol. Res. 2010, 106, 395-401.
-
(2010)
Parasitol. Res.
, vol.106
, pp. 395-401
-
-
Magalhães, L.G.1
Kapadia, G.J.2
Da Silva Tonuci, L.R.3
Caixeta, S.C.4
Parreira, N.A.5
Rodrigues, V.6
Da Silva Filho, A.A.7
-
122
-
-
70449568249
-
Drug discovery for schistosomiasis: Hit and lead compounds identified in a library of known drugs by medium-throughput phenotypic screening
-
Abdulla, M.-H.; Ruelas, D.S.; Wolff, B.; Snedecor, J.; Lim, K.-C.; Xu, F.; Renslo, A.R.; Williams, J.; McKerrow, J.H.; Caffrey, C.R. Drug discovery for schistosomiasis: Hit and lead compounds identified in a library of known drugs by medium-throughput phenotypic screening. PLoS Negl. Trop. Dis. 2009, 3, e478.
-
(2009)
PLoS Negl. Trop. Dis.
, vol.3
, pp. e478
-
-
Abdulla, M.-H.1
Ruelas, D.S.2
Wolff, B.3
Snedecor, J.4
Lim, K.-C.5
Xu, F.6
Renslo, A.R.7
Williams, J.8
McKerrow, J.H.9
Caffrey, C.R.10
-
123
-
-
84890130109
-
Evaluation of dihydroisocoumarins produced by the endophytic fungus Arthrinium state of Apiospora montagnei against Schistosoma mansoni
-
Ramos, H.P.; Simão, M.R.; de Souza, J.M.; Magalhães, L.G.; Rodrigues, V.; Ambrósio, S.R.; Said, S. Evaluation of dihydroisocoumarins produced by the endophytic fungus Arthrinium state of Apiospora montagnei against Schistosoma mansoni. Nat. Prod. Res. 2013, 27, 2240-2243.
-
(2013)
Nat. Prod. Res.
, vol.27
, pp. 2240-2243
-
-
Ramos, H.P.1
Simão, M.R.2
De Souza, J.M.3
Magalhães, L.G.4
Rodrigues, V.5
Ambrósio, S.R.6
Said, S.7
-
124
-
-
62949138385
-
In vitro schistosomicidal activity of curcumin against Schistosoma mansoni adult worms
-
Magalhães, L.G.; Machado, C.B.; Morais, E.R.; Moreira, E.B.D.C.; Soares, C.S.; da Silva, S.H.; Da Silva Filho, A.A.; Rodrigues, V. In vitro schistosomicidal activity of curcumin against Schistosoma mansoni adult worms. Parasitol. Res. 2009, 104, 1197-1201.
-
(2009)
Parasitol. Res.
, vol.104
, pp. 1197-1201
-
-
Magalhães, L.G.1
Machado, C.B.2
Morais, E.R.3
Moreira, E.B.D.C.4
Soares, C.S.5
Da Silva, S.H.6
Da Silva Filho, A.A.7
Rodrigues, V.8
-
125
-
-
1642564603
-
Inhibition of proteasomal function by curcumin induces apoptosis through mitochondrial pathway
-
Jana, N.R.; Dikshit, P.; Goswami, A.; Nukina, N. Inhibition of proteasomal function by curcumin induces apoptosis through mitochondrial pathway. J. Biol. Chem. 2004, 279, 11680-11685.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 11680-11685
-
-
Jana, N.R.1
Dikshit, P.2
Goswami, A.3
Nukina, N.4
-
126
-
-
54749132655
-
Curcumin inhibits the proteasome activity in human colon cancer cells in vitro and in vivo
-
Milacic, V.; Banerjee, S.; Landis-Piwowar, K.R.; Sarkar, F.H.; Majumdar, A.P.N.; Dou, Q.P. Curcumin inhibits the proteasome activity in human colon cancer cells in vitro and in vivo. Cancer Res. 2008, 68, 7283-7292.
-
(2008)
Cancer Res.
, vol.68
, pp. 7283-7292
-
-
Milacic, V.1
Banerjee, S.2
Landis-Piwowar, K.R.3
Sarkar, F.H.4
Majumdar, A.P.N.5
Dou, Q.P.6
-
127
-
-
44349089757
-
Natural product isolation
-
Sticher, O. Natural product isolation. Nat. Prod. Rep. 2008, 25, 517-554.
-
(2008)
Nat. Prod. Rep.
, vol.25
, pp. 517-554
-
-
Sticher, O.1
-
128
-
-
84874956949
-
Natural product isolation-how to get from biological material to pure compounds
-
Bucar, F.; Wube, A.; Schmid, M. Natural product isolation-how to get from biological material to pure compounds. Nat. Prod. Rep. 2013, 30, 525-545.
-
(2013)
Nat. Prod. Rep.
, vol.30
, pp. 525-545
-
-
Bucar, F.1
Wube, A.2
Schmid, M.3
-
129
-
-
77949653928
-
In vitro and in vivo trematode models for chemotherapeutic studies
-
Keiser, J. In vitro and in vivo trematode models for chemotherapeutic studies. Parasitology 2010, 137, 589-603.
-
(2010)
Parasitology
, vol.137
, pp. 589-603
-
-
Keiser, J.1
-
130
-
-
35448999738
-
Schistosomes: Challenges in compound screening
-
Ramirez, B.; Bickle, Q.; Yousif, F.; Fakorede, F.; Mouries, M.-A.; Nwaka, S. Schistosomes: Challenges in compound screening. Expert Opin. Drug Discov. 2007, 2, S53-S61.
-
(2007)
Expert Opin. Drug Discov.
, vol.2
, pp. S53-S61
-
-
Ramirez, B.1
Bickle, Q.2
Yousif, F.3
Fakorede, F.4
Mouries, M.-A.5
Nwaka, S.6
-
131
-
-
78149266039
-
Comparison of microscopy and Alamar blue reduction in a larval based assay for schistosome drug screening
-
Mansour, N.R.; Bickle, Q.D. Comparison of microscopy and Alamar blue reduction in a larval based assay for schistosome drug screening. PLoS Negl. Trop. Dis. 2010, 4, e795.
-
(2010)
PLoS Negl. Trop. Dis.
, vol.4
, pp. e795
-
-
Mansour, N.R.1
Bickle, Q.D.2
-
132
-
-
84864615611
-
Whole organism high-content screening by label-free, image-based Bayesian classification for parasitic diseases
-
Paveley, R.A.; Mansour, N.R.; Hallyburton, I.; Bleicher, L.S.; Benn, A.E.; Mikic, I.; Guidi, A.; Gilbert, I.H.; Hopkins, A.L.; Bickle, Q.D. Whole organism high-content screening by label-free, image-based Bayesian classification for parasitic diseases. PLoS Negl. Trop. Dis. 2012, 6, e1762.
-
(2012)
PLoS Negl. Trop. Dis.
, vol.6
, pp. e1762
-
-
Paveley, R.A.1
Mansour, N.R.2
Hallyburton, I.3
Bleicher, L.S.4
Benn, A.E.5
Mikic, I.6
Guidi, A.7
Gilbert, I.H.8
Hopkins, A.L.9
Bickle, Q.D.10
-
133
-
-
84862265241
-
Quantification and clustering of phenotypic screening data using time-series analysis for chemotherapy of schistosomiasis
-
Lee, H.; Moody-Davis, A.; Saha, U.; Suzuki, B.M.; Asarnow, D.; Chen, S.; Arkin, M.; Caffrey, C.R.; Singh, R. Quantification and clustering of phenotypic screening data using time-series analysis for chemotherapy of schistosomiasis. BMC Genomics 2012, 13 (Suppl. 1), S4.
-
(2012)
BMC Genomics
, vol.13
, pp. S4
-
-
Lee, H.1
Moody-Davis, A.2
Saha, U.3
Suzuki, B.M.4
Asarnow, D.5
Chen, S.6
Arkin, M.7
Caffrey, C.R.8
Singh, R.9
-
134
-
-
84880299041
-
Automated imaging and other developments in whole-organism anthelmintic screening
-
Paveley, R.A.; Bickle, Q.D. Automated imaging and other developments in whole-organism anthelmintic screening. Parasite Immunol. 2007, 35, 302-313.
-
(2007)
Parasite Immunol.
, vol.35
, pp. 302-313
-
-
Paveley, R.A.1
Bickle, Q.D.2
-
135
-
-
84902210226
-
Increasing the content of high-content screening: An overview
-
Singh, S.; Carpenter, A.E.; Genovesio, A. Increasing the Content of High-Content Screening: An Overview. J. Biomol. Screen. 2014, 19, 640-650.
-
(2014)
J. Biomol. Screen.
, vol.19
, pp. 640-650
-
-
Singh, S.1
Carpenter, A.E.2
Genovesio, A.3
-
136
-
-
84878572284
-
Segmenting the etiological agent of schistosomiasis for high-content screening
-
Asarnow, D.E.; Singh, R. Segmenting the etiological agent of schistosomiasis for high-content screening. IEEE Trans. Med. Imaging 2013, 32, 1007-1018.
-
(2013)
IEEE Trans. Med. Imaging
, vol.32
, pp. 1007-1018
-
-
Asarnow, D.E.1
Singh, R.2
-
137
-
-
77957914128
-
Development and validation of a quantitative, high-throughput, fluorescent-based bioassay to detect schistosoma viability
-
Peak, E.; Chalmers, I.W.; Hoffmann, K.F. Development and validation of a quantitative, high-throughput, fluorescent-based bioassay to detect schistosoma viability. PLoS Negl. Trop. Dis. 2010, 4, e759.
-
(2010)
PLoS Negl. Trop. Dis.
, vol.4
, pp. e759
-
-
Peak, E.1
Chalmers, I.W.2
Hoffmann, K.F.3
-
138
-
-
81355161288
-
Molecular docking for virtual screening of natural product databases
-
Ma, D.-L.; Chan, D.S.-H.; Leung, C.-H. Molecular docking for virtual screening of natural product databases. Chem. Sci. 2011, 2, 1656-1665.
-
(2011)
Chem. Sci.
, vol.2
, pp. 1656-1665
-
-
Ma, D.-L.1
Chan, D.S.-H.2
Leung, C.-H.3
-
139
-
-
84908251020
-
Discovery of inhibitors of Schistosoma mansoni HDAC8 by combining homology modeling, virtual screening, and in vitro validation
-
Kannan, S.; Melesina, J.; Hauser, A.-T.; Chakrabarti, A.; Heimburg, T.; Schmidtkunz, K.; Walter, A.; Marek, M.; Pierce, R.J.; Romier, C.; et al. Discovery of inhibitors of Schistosoma mansoni HDAC8 by combining homology modeling, virtual screening, and in vitro validation. J. Chem. Inf. Model. 2014, 54, 3005-3019.
-
(2014)
J. Chem. Inf. Model.
, vol.54
, pp. 3005-3019
-
-
Kannan, S.1
Melesina, J.2
Hauser, A.-T.3
Chakrabarti, A.4
Heimburg, T.5
Schmidtkunz, K.6
Walter, A.7
Marek, M.8
Pierce, R.J.9
Romier, C.10
-
140
-
-
84878747400
-
3-Oxoacyl-ACP reductase from Schistosoma japonicum: Integrated in silico- in vitro strategy for discovering antischistosomal lead compounds
-
Liu, J.; Dyer, D.; Wang, J.; Wang, S.; Du, X.; Xu, B.; Zhang, H.; Wang, X.; Hu, W. 3-Oxoacyl-ACP reductase from Schistosoma japonicum: Integrated in silico- in vitro strategy for discovering antischistosomal lead compounds. PLoS One 2013, 8, e64984.
-
(2013)
PLoS One
, vol.8
, pp. e64984
-
-
Liu, J.1
Dyer, D.2
Wang, J.3
Wang, S.4
Du, X.5
Xu, B.6
Zhang, H.7
Wang, X.8
Hu, W.9
-
141
-
-
84878432195
-
Aldose reductase from Schistosoma japonicum: Crystallization and structure-based inhibitor screening for discovering antischistosomal lead compounds
-
Liu, J.; Dyer, D.H.; Cheng, J.; Wang, J.; Wang, S.; Yang, Z.; Wang, X.; Hu, W. Aldose reductase from Schistosoma japonicum: Crystallization and structure-based inhibitor screening for discovering antischistosomal lead compounds. Parasit. Vectors 2013, 6, 162.
-
(2013)
Parasit. Vectors
, vol.6
, pp. 162
-
-
Liu, J.1
Dyer, D.H.2
Cheng, J.3
Wang, J.4
Wang, S.5
Yang, Z.6
Wang, X.7
Hu, W.8
-
142
-
-
77957235318
-
Discovery of new inhibitors of Schistosoma mansoni PNP by pharmacophore-based virtual screening
-
Postigo, M.P.; Guido, R.V.C.; Oliva, G.; Castilho, M.S.; da R Pitta, I.; de Albuquerque, J.F.C.; Andricopulo, A.D. Discovery of new inhibitors of Schistosoma mansoni PNP by pharmacophore-based virtual screening. J. Chem. Inf. Model. 2010, 50, 1693-1705.
-
(2010)
J. Chem. Inf. Model.
, vol.50
, pp. 1693-1705
-
-
Postigo, M.P.1
Guido, R.V.C.2
Oliva, G.3
Castilho, M.S.4
Pitta, D.R.5
De Albuquerque, J.F.C.6
Andricopulo, A.D.7
-
143
-
-
84878798892
-
Assessing the performance of 3D pharmacophore models in virtual screening: How good are they?
-
Braga, R.C.; Andrade, C.H. Assessing the performance of 3D pharmacophore models in virtual screening: How good are they? Curr. Top. Med. Chem. 2013, 13, 1127-1138.
-
(2013)
Curr. Top. Med. Chem.
, vol.13
, pp. 1127-1138
-
-
Braga, R.C.1
Andrade, C.H.2
-
144
-
-
84875470601
-
Development of a natural products database from the biodiversity of Brazil
-
Valli, M.; dos Santos, R.N.; Figueira, L.D.; Nakajima, C.H.; Castro-Gamboa, I.; Andricopulo, A.D.; Bolzani, V.S. Development of a natural products database from the biodiversity of Brazil. J. Nat. Prod. 2013, 76, 439-444.
-
(2013)
J. Nat. Prod.
, vol.76
, pp. 439-444
-
-
Valli, M.1
Dos Santos, R.N.2
Figueira, L.D.3
Nakajima, C.H.4
Castro-Gamboa, I.5
Andricopulo, A.D.6
Bolzani, V.S.7
-
145
-
-
33644878571
-
SuperNatural: A searchable database of available natural compounds
-
Dunkel, M.; Fullbeck, M.; Neumann, S.; Preissner, R. SuperNatural: A searchable database of available natural compounds. Nucleic Acids Res. 2006, 34, D678-D683.
-
(2006)
Nucleic Acids Res.
, vol.34
, pp. D678-D683
-
-
Dunkel, M.1
Fullbeck, M.2
Neumann, S.3
Preissner, R.4
-
146
-
-
37249035096
-
Phytochemical informatics of traditional Chinese medicine and therapeutic relevance
-
Ehrman, T.M.; Barlow, D.J.; Hylands, P.J. Phytochemical informatics of traditional Chinese medicine and therapeutic relevance. J. Chem. Inf. Model. 2006, 47, 2316-2334.
-
(2006)
J. Chem. Inf. Model.
, vol.47
, pp. 2316-2334
-
-
Ehrman, T.M.1
Barlow, D.J.2
Hylands, P.J.3
-
147
-
-
84860634242
-
Seaweed metabolite database (SWMD): A database of natural compounds from marine algae
-
Davis, G.D.J.; Vasanthi, A.H.R. Seaweed metabolite database (SWMD): A database of natural compounds from marine algae. Bioinformation 2011, 5, 361-364.
-
(2011)
Bioinformation
, vol.5
, pp. 361-364
-
-
Davis, G.D.J.1
Vasanthi, A.H.R.2
-
148
-
-
84870443681
-
Virtual screening methods as tools for drug lead discovery from large chemical libraries
-
Ma, X.H.; Zhu, F.; Liu, X.; Shi, Z.; Zhang, J.X.; Yang, S.Y.; Wei, Y.Q.; Chen, Y.Z. Virtual screening methods as tools for drug lead discovery from large chemical libraries. Curr. Med. Chem. 2012, 19, 5562-5571.
-
(2012)
Curr. Med. Chem.
, vol.19
, pp. 5562-5571
-
-
Ma, X.H.1
Zhu, F.2
Liu, X.3
Shi, Z.4
Zhang, J.X.5
Yang, S.Y.6
Wei, Y.Q.7
Chen, Y.Z.8
-
149
-
-
84903739566
-
Virtual screening strategies in medicinal chemistry: The state of the art and current challenges
-
Braga, R.C.; Alves, V.M.; Silva, A.C.; Nascimento, M.N.; Silva, F.C.; Liao, L.M.; Andrade, C.H. Virtual screening strategies in medicinal chemistry: The state of the art and current challenges. Curr. Top. Med. Chem. 2014, 14, 1899-1912.
-
(2014)
Curr. Top. Med. Chem.
, vol.14
, pp. 1899-1912
-
-
Braga, R.C.1
Alves, V.M.2
Silva, A.C.3
Nascimento, M.N.4
Silva, F.C.5
Liao, L.M.6
Andrade, C.H.7
-
150
-
-
84856461929
-
Databases aim to bridge the East-West divide of drug discovery
-
Sanderson, K. Databases aim to bridge the East-West divide of drug discovery. Nat. Med. 2011, 17, 1531.
-
(2011)
Nat. Med.
, vol.17
, pp. 1531
-
-
Sanderson, K.1
-
151
-
-
79251561193
-
TCM Database@Taiwan: The world's largest traditional Chinese medicine database for drug screening in silico
-
Chen, C.Y.-C. TCM Database@Taiwan: The world's largest traditional Chinese medicine database for drug screening in silico. PLoS One 2011, 6, e15939.
-
(2011)
PLoS One
, vol.6
, pp. e15939
-
-
Chen, C.Y.-C.1
-
152
-
-
84921690973
-
-
Available online accessed on 12 December 2014
-
Dictionary of Natural Products. Available online: http://www.chemnetbase.com/ (accessed on 12 December 2014).
-
-
-
Dictionary of Natural Products1
-
153
-
-
78651326779
-
HIT: Linking herbal active ingredients to targets
-
Ye, H.; Ye, L.; Kang, H.; Zhang, D.; Tao, L.; Tang, K.; Liu, X.; Zhu, R.; Liu, Q.; Chen, Y.Z.; et al. HIT: linking herbal active ingredients to targets. Nucleic Acids Res. 2011, 39, D1055-D1059.
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. D1055-D1059
-
-
Ye, H.1
Ye, L.2
Kang, H.3
Zhang, D.4
Tao, L.5
Tang, K.6
Liu, X.7
Zhu, R.8
Liu, Q.9
Chen, Y.Z.10
-
154
-
-
84876560772
-
NPACT: Naturally Occurring Plant-based Anti-cancer Compound-Activity-Target database
-
Mangal, M.; Sagar, P.; Singh, H.; Raghava, G.P.S.; Agarwal, S.M. NPACT: Naturally Occurring Plant-based Anti-cancer Compound-Activity-Target database. Nucleic Acids Res. 2013, 41, D1124-D1129.
-
(2013)
Nucleic Acids Res.
, vol.41
, pp. D1124-D1129
-
-
Mangal, M.1
Sagar, P.2
Singh, H.3
Raghava, G.P.S.4
Agarwal, S.M.5
-
155
-
-
84921653623
-
-
Available online accessed on 12 December 2014
-
Database of Indonesian Medicinal Plants. Available online: http://herbaldb.farmasi.ui.ac.id/ (accessed on 12 December 2014).
-
-
-
Database of Indonesian Medicinal Plants1
-
156
-
-
84921635428
-
-
Available online accessed on 12 December 2014
-
Greenpharma Natural Compound Library. Available online: http://www.greenpharma.com/products/ (accessed on 12 December 2014).
-
-
-
Greenpharma Natural Compound Library1
-
157
-
-
84908108272
-
TMDB: A literature-curated database for small molecular compounds found from tea
-
Yue, Y.; Chu, G.-X.; Liu, X.-S.; Tang, X.; Wang, W.; Liu, G.-J.; Yang, T.; Ling, T.-J.; Wang, X.-G.; Zhang, Z.-Z.; et al. TMDB: A literature-curated database for small molecular compounds found from tea. BMC Plant Biol . 2014, 14, 243.
-
(2014)
BMC Plant Biol
, vol.14
, pp. 243
-
-
Yue, Y.1
Chu, G.-X.2
Liu, X.-S.3
Tang, X.4
Wang, W.5
Liu, G.-J.6
Yang, T.7
Ling, T.-J.8
Wang, X.-G.9
Zhang, Z.-Z.10
-
158
-
-
84903897661
-
MAPS Database: Medicinal plant activities, phytochemical and structural database
-
Ashfaq, U.A.; Mumtaz, A.; Qamar, T.U.; Fatima, T. MAPS Database: Medicinal plant Activities, Phytochemical and Structural Database. Bioinformation 2013, 9, 993-995.
-
(2013)
Bioinformation
, vol.9
, pp. 993-995
-
-
Ashfaq, U.A.1
Mumtaz, A.2
Qamar, T.U.3
Fatima, T.4
-
159
-
-
84878666771
-
TIPdb: A database of anticancer, antiplatelet, and antituberculosis phytochemicals from indigenous plants in Taiwan
-
Lin, Y.-C.; Wang, C.-C.; Chen, I.-S.; Jheng, J.-L.; Li, J.-H.; Tung, C.-W. TIPdb: A database of anticancer, antiplatelet, and antituberculosis phytochemicals from indigenous plants in Taiwan. Sci. World J. 2013, 2013, doi:10.1155/2013/736386.
-
(2013)
Sci. World J.
, vol.2013
-
-
Lin, Y.-C.1
Wang, C.-C.2
Chen, I.-S.3
Jheng, J.-L.4
Li, J.-H.5
Tung, C.-W.6
-
160
-
-
84987657364
-
TIPdb-3D: The three-dimensional structure database of phytochemicals from Taiwan indigenous plants
-
Tung, C.-W.; Lin, Y.-C.; Chang, H.-S.; Wang, C.-C.; Chen, I.-S.; Jheng, J.-L.; Li, J.-H. TIPdb-3D: the three-dimensional structure database of phytochemicals from Taiwan indigenous plants. Database (Oxford) 2014, 2014, bau055.
-
(2014)
Database (Oxford)
, vol.2014
, pp. bau055
-
-
Tung, C.-W.1
Lin, Y.-C.2
Chang, H.-S.3
Wang, C.-C.4
Chen, I.-S.5
Jheng, J.-L.6
Li, J.-H.7
-
161
-
-
84921690972
-
-
Available online accessed on 12 December 2014
-
AMRI's Natural Product Library. Available online: http://www.amriglobal.com/ (accessed on 12 December 2014).
-
-
-
AMRI's Natural Product Library1
-
162
-
-
85026053788
-
Glossary of terms used in medicinal chemistry (IUPAC Recommendations 1998)
-
Wermuth, C.; Ganellin, C.; Lindberg, P.; Mitscher, L. Glossary of terms used in medicinal chemistry (IUPAC Recommendations 1998). Pure Appl. Chem. 1998, 70, 1129-1143.
-
(1998)
Pure Appl. Chem.
, vol.70
, pp. 1129-1143
-
-
Wermuth, C.1
Ganellin, C.2
Lindberg, P.3
Mitscher, L.4
-
163
-
-
5644236834
-
Pharmacophore modeling and three dimensional database searching for drug design using catalyst: Recent advances
-
Güner, O.; Clement, O.; Kurogi, Y. Pharmacophore modeling and three dimensional database searching for drug design using catalyst: Recent advances. Curr. Med. Chem. 2004, 11, 2991-3005.
-
(2004)
Curr. Med. Chem.
, vol.11
, pp. 2991-3005
-
-
Güner, O.1
Clement, O.2
Kurogi, Y.3
-
164
-
-
34249022980
-
GALAHAD: 1. Pharmacophore identification by hypermolecular alignment of ligands in 3D
-
Richmond, N.J.; Abrams, C.A.; Wolohan, P.R.N.; Abrahamian, E.; Willett, P.; Clark, R.D. GALAHAD: 1. pharmacophore identification by hypermolecular alignment of ligands in 3D. J. Comput. Aided Mol. Des. 2006, 20, 567-587.
-
(2006)
J. Comput. Aided Mol. Des.
, vol.20
, pp. 567-587
-
-
Richmond, N.J.1
Abrams, C.A.2
Wolohan, P.R.N.3
Abrahamian, E.4
Willett, P.5
Clark, R.D.6
-
165
-
-
0030137662
-
Identification of common functional configurations among molecules
-
Barnum, D.; Greene, J.; Smellie, A.; Sprague, P. Identification of common functional configurations among molecules. J. Chem. Inf. Comput. Sci. 1996, 36, 563-571.
-
(1996)
J. Chem. Inf. Comput. Sci.
, vol.36
, pp. 563-571
-
-
Barnum, D.1
Greene, J.2
Smellie, A.3
Sprague, P.4
-
166
-
-
33845868822
-
PHASE: A new engine for pharmacophore perception, 3D QSAR model development, and 3D database screening: 1. Methodology and preliminary results
-
Dixon, S.L.; Smondyrev, A.M.; Knoll, E.H.; Rao, S.N.; Shaw, D.E.; Friesner, R.A. PHASE: A new engine for pharmacophore perception, 3D QSAR model development, and 3D database screening: 1. Methodology and preliminary results. J. Comput. Aided. Mol. Des. 2006, 20, 647-671.
-
(2006)
J. Comput. Aided. Mol. Des.
, vol.20
, pp. 647-671
-
-
Dixon, S.L.1
Smondyrev, A.M.2
Knoll, E.H.3
Rao, S.N.4
Shaw, D.E.5
Friesner, R.A.6
-
167
-
-
84899881824
-
QSAR modeling: Where have you been? Where are you going to?
-
Cherkasov, A.; Muratov, E.N.; Fourches, D.; Varnek, A.; Baskin, I.I.; Cronin, M.; Dearden, J.; Gramatica, P.; Martin, Y.C.; Todeschini, R.; et al. QSAR modeling: Where have you been? Where are you going to? J. Med. Chem. 2014, 57, 4977-5010.
-
(2014)
J. Med. Chem.
, vol.57
, pp. 4977-5010
-
-
Cherkasov, A.1
Muratov, E.N.2
Fourches, D.3
Varnek, A.4
Baskin, I.I.5
Cronin, M.6
Dearden, J.7
Gramatica, P.8
Martin, Y.C.9
Todeschini, R.10
-
168
-
-
84904729887
-
3D-QSAR approaches in drug design: Perspectives to generate reliable CoMFA models
-
Melo-Filho, C.C.; Braga, R.C.; Andrade, C.H. 3D-QSAR Approaches in Drug Design: Perspectives to Generate Reliable CoMFA Models. Curr. Comput. Aided Drug Des. 2014, 10, 148-159.
-
(2014)
Curr. Comput. Aided Drug Des.
, vol.10
, pp. 148-159
-
-
Melo-Filho, C.C.1
Braga, R.C.2
Andrade, C.H.3
-
169
-
-
84875458244
-
Discovery of new potential hits of Plasmodium falciparum enoyl-ACP reductase through ligand- and structure-based drug design approaches
-
Neves, B.J.; Bueno, R.V.; Braga, R.C.; Andrade, C.H. Discovery of new potential hits of Plasmodium falciparum enoyl-ACP reductase through ligand- and structure-based drug design approaches. Bioorg. Med. Chem. Lett. 2013, 23, 2436-2441.
-
(2013)
Bioorg. Med. Chem. Lett.
, vol.23
, pp. 2436-2441
-
-
Neves, B.J.1
Bueno, R.V.2
Braga, R.C.3
Andrade, C.H.4
-
170
-
-
84872327877
-
Structural and chemical basis for enhanced affinity to a series of mycobacterial thymidine monophosphate kinase inhibitors: Fragment-based QSAR and QM/MM docking studies
-
Bueno, R.V.; Toledo, N.R.; Neves, B.J.; Braga, R.C.; Andrade, C.H. Structural and chemical basis for enhanced affinity to a series of mycobacterial thymidine monophosphate kinase inhibitors: Fragment-based QSAR and QM/MM docking studies. J. Mol. Model. 2013, 19, 179-192.
-
(2013)
J. Mol. Model.
, vol.19
, pp. 179-192
-
-
Bueno, R.V.1
Toledo, N.R.2
Neves, B.J.3
Braga, R.C.4
Andrade, C.H.5
-
171
-
-
77956964002
-
Best practices for QSAR model development, validation, and exploitation
-
Tropsha, A. Best Practices for QSAR Model Development, Validation, and Exploitation. Mol. Inf. 2010, 29, 476-488.
-
(2010)
Mol. Inf.
, vol.29
, pp. 476-488
-
-
Tropsha, A.1
-
172
-
-
84874425485
-
Discovery of novel antimalarial compounds enabled by QSAR-based virtual screening
-
Zhang, L.; Fourches, D.; Sedykh, A.; Zhu, H.; Golbraikh, A.; Ekins, S.; Clark, J.; Connelly, M.C.; Sigal, M.; Hodges, D.; et al. Discovery of novel antimalarial compounds enabled by QSAR-based virtual screening. J. Chem. Inf. Model. 2013, 53, 475-492.
-
(2013)
J. Chem. Inf. Model.
, vol.53
, pp. 475-492
-
-
Zhang, L.1
Fourches, D.2
Sedykh, A.3
Zhu, H.4
Golbraikh, A.5
Ekins, S.6
Clark, J.7
Connelly, M.C.8
Sigal, M.9
Hodges, D.10
-
173
-
-
84857514268
-
Comparative studies on some metrics for external validation of QSPR models
-
Roy, K.; Mitra, I.; Kar, S.; Ojha, P.K.; Das, R.N.; Kabir, H. Comparative studies on some metrics for external validation of QSPR models. J. Chem. Inf. Model. 2012, 52, 396-408.
-
(2012)
J. Chem. Inf. Model.
, vol.52
, pp. 396-408
-
-
Roy, K.1
Mitra, I.2
Kar, S.3
Ojha, P.K.4
Das, R.N.5
Kabir, H.6
-
174
-
-
84861172684
-
On the use of the metric rm2 as an effective tool for validation of QSAR models in computational drug design and predictive toxicology
-
Roy, K.; Mitra, I. On the use of the metric rm2 as an effective tool for validation of QSAR models in computational drug design and predictive toxicology. Mini Rev. Med. Chem. 2012, 12, 491-504.
-
(2012)
Mini Rev. Med. Chem.
, vol.12
, pp. 491-504
-
-
Roy, K.1
Mitra, I.2
-
175
-
-
84868210651
-
Introduction of rm2 (rank) metric incorporating rank-order predictions as an additional tool for validation of QSAR/QSPR models
-
Roy, K.; Mitra, I.; Ojha, P.K.; Kar, S.; Das, R.N.; Kabir, H. Introduction of rm2 (rank) metric incorporating rank-order predictions as an additional tool for validation of QSAR/QSPR models. Chemom. Intell. Lab. Syst. 2012, 118, 200-210.
-
(2012)
Chemom. Intell. Lab. Syst.
, vol.118
, pp. 200-210
-
-
Roy, K.1
Mitra, I.2
Ojha, P.K.3
Kar, S.4
Das, R.N.5
Kabir, H.6
-
176
-
-
84870526047
-
On the development and validation of QSAR models
-
Gramatica, P. On the development and validation of QSAR models. Methods Mol. Biol. 2013, 930, 499-526.
-
(2013)
Methods Mol. Biol.
, vol.930
, pp. 499-526
-
-
Gramatica, P.1
-
177
-
-
80053295024
-
Real external predictivity of QSAR models: How to evaluate it? Comparison of different validation criteria and proposal of using the concordance correlation coefficient
-
Chirico, N.; Gramatica, P. Real external predictivity of QSAR models: How to evaluate it? Comparison of different validation criteria and proposal of using the concordance correlation coefficient. J. Chem. Inf. Model. 2011, 51, 2320-2335.
-
(2011)
J. Chem. Inf. Model.
, vol.51
, pp. 2320-2335
-
-
Chirico, N.1
Gramatica, P.2
-
178
-
-
84865466657
-
Real external predictivity of QSAR models. Part 2; New intercomparable thresholds for different validation criteria and the need for scatter plot inspection
-
Chirico, N.; Gramatica, P. Real external predictivity of QSAR models. Part 2; New intercomparable thresholds for different validation criteria and the need for scatter plot inspection. J. Chem. Inf. Model. 2012, 52, 2044-2058.
-
(2012)
J. Chem. Inf. Model.
, vol.52
, pp. 2044-2058
-
-
Chirico, N.1
Gramatica, P.2
-
179
-
-
78149410394
-
PKa based protonation states and microspecies for protein-ligand docking
-
Ten Brink, T.; Exner, T.E. pKa based protonation states and microspecies for protein-ligand docking. J. Comput. Aided Mol. Des. 2010, 24, 935-942.
-
(2010)
J. Comput. Aided Mol. Des.
, vol.24
, pp. 935-942
-
-
Ten Brink, T.1
Exner, T.E.2
-
180
-
-
33745199815
-
Virtual ligand screening: Strategies, perspectives and limitations
-
Klebe, G. Virtual ligand screening: Strategies, perspectives and limitations. Drug Discov. Today 2006, 11, 580-594.
-
(2006)
Drug Discov. Today
, vol.11
, pp. 580-594
-
-
Klebe, G.1
-
181
-
-
84911401229
-
Structure-based virtual screening for drug discovery: Principles, applications and recent advances
-
Lionta, E.; Spyrou, G.; Vassilatis, D.K.; Cournia, Z. Structure-based virtual screening for drug discovery: Principles, applications and recent advances. Curr. Top. Med. Chem. 2014, 14, 1923-1938.
-
(2014)
Curr. Top. Med. Chem.
, vol.14
, pp. 1923-1938
-
-
Lionta, E.1
Spyrou, G.2
Vassilatis, D.K.3
Cournia, Z.4
-
182
-
-
79952262090
-
FRED pose prediction and virtual screening accuracy
-
McGann, M. FRED pose prediction and virtual screening accuracy. J. Chem. Inf. Model. 2011, 51, 578-596.
-
(2011)
J. Chem. Inf. Model.
, vol.51
, pp. 578-596
-
-
McGann, M.1
-
183
-
-
84867328344
-
FRED and HYBRID docking performance on standardized datasets
-
McGann, M. FRED and HYBRID docking performance on standardized datasets. J. Comput. Aided Mol. Des. 2012, 26, 897-906.
-
(2012)
J. Comput. Aided Mol. Des.
, vol.26
, pp. 897-906
-
-
McGann, M.1
-
184
-
-
84921691157
-
-
OpenEye Scientific Software, Inc.: Santa Fe, NM, USA Available online accessed on 10 December 2014
-
OEDocking, version 3.0.1; OpenEye Scientific Software, Inc.: Santa Fe, NM, USA, 2014. Available online: http://www.eyesopen.com/oedocking (accessed on 10 December 2014).
-
(2014)
OEDocking, Version 3.0.1
-
-
-
185
-
-
84904971603
-
Structure-based virtual screening approach for discovery of covalently bound ligands
-
Toledo Warshaviak, D.; Golan, G.; Borrelli, K.W.; Zhu, K.; Kalid, O. Structure-based virtual screening approach for discovery of covalently bound ligands. J. Chem. Inf. Model. 2014, 54, 1941-1950.
-
(2014)
J. Chem. Inf. Model.
, vol.54
, pp. 1941-1950
-
-
Toledo Warshaviak, D.1
Golan, G.2
Borrelli, K.W.3
Zhu, K.4
Kalid, O.5
-
186
-
-
6344294057
-
FlexX-Scan: Fast, structure-based virtual screening
-
Schellhammer, I.; Rarey, M. FlexX-Scan: Fast, structure-based virtual screening. Proteins 2004, 57, 504-517.
-
(2004)
Proteins
, vol.57
, pp. 504-517
-
-
Schellhammer, I.1
Rarey, M.2
-
187
-
-
0041919542
-
Improved protein-ligand docking using GOLD
-
Verdonk, M.L.; Cole, J.C.; Hartshorn, M.J.; Murray, C.W.; Taylor, R.D. Improved protein-ligand docking using GOLD. Proteins 2003, 52, 609-623.
-
(2003)
Proteins
, vol.52
, pp. 609-623
-
-
Verdonk, M.L.1
Cole, J.C.2
Hartshorn, M.J.3
Murray, C.W.4
Taylor, R.D.5
-
188
-
-
84861118556
-
Outstanding challenges in protein-ligand docking and structure-based virtual screening
-
Waszkowycz, B.; Clark, D.E.; Gancia, E. Outstanding challenges in protein-ligand docking and structure-based virtual screening. Wiley Interdiscip. Rev. Comput. Mol. Sci. 2011, 1, 229-259.
-
(2011)
Wiley Interdiscip. Rev. Comput. Mol. Sci.
, vol.1
, pp. 229-259
-
-
Waszkowycz, B.1
Clark, D.E.2
Gancia, E.3
-
189
-
-
78649898335
-
Protein flexibility and ligand recognition: Challenges for molecular modeling
-
Spyrakis, F.; BidonChanal, A.; Barril, X.; Luque, F.J. Protein flexibility and ligand recognition: Challenges for molecular modeling. Curr. Top. Med. Chem. 2011, 11, 192-210.
-
(2011)
Curr. Top. Med. Chem.
, vol.11
, pp. 192-210
-
-
Spyrakis, F.1
BidonChanal, A.2
Barril, X.3
Luque, F.J.4
-
190
-
-
84891489378
-
Optimization of compound ranking for structure-based virtual ligand screening using an established FRED-Surflex consensus approach
-
Du, J.; Bleylevens, I.W.M.; Bitorina, A.V.; Wichapong, K.; Nicolaes, G.A.F. Optimization of compound ranking for structure-based virtual ligand screening using an established FRED-Surflex consensus approach. Chem. Biol. Drug Des. 2014, 83, 37-51.
-
(2014)
Chem. Biol. Drug Des.
, vol.83
, pp. 37-51
-
-
Du, J.1
Bleylevens, I.W.M.2
Bitorina, A.V.3
Wichapong, K.4
Nicolaes, G.A.F.5
-
191
-
-
84905020680
-
Consensus scoring approach to identify the inhibitors of AMPactivated protein kinase α2 with virtual screening
-
Park, H.; Eom, J.-W.; Kim, Y.-H. Consensus scoring approach to identify the inhibitors of AMPactivated protein kinase α2 with virtual screening. J. Chem. Inf. Model. 2014, 54, 2139-2146.
-
(2014)
J. Chem. Inf. Model.
, vol.54
, pp. 2139-2146
-
-
Park, H.1
Eom, J.-W.2
Kim, Y.-H.3
-
192
-
-
33748667774
-
Consensus scoring for protein-ligand interactions
-
Feher, M. Consensus scoring for protein-ligand interactions. Drug Discov. Today 2006, 11, 421-428.
-
(2006)
Drug Discov. Today
, vol.11
, pp. 421-428
-
-
Feher, M.1
-
193
-
-
13844320566
-
LigandScout: 3-D pharmacophores derived from protein-bound ligands and their use as virtual screening filters
-
Wolber, G.; Langer, T. LigandScout: 3-D pharmacophores derived from protein-bound ligands and their use as virtual screening filters. J. Chem. Inf. Model. 2005, 45, 160-169.
-
(2005)
J. Chem. Inf. Model.
, vol.45
, pp. 160-169
-
-
Wolber, G.1
Langer, T.2
-
194
-
-
33947576378
-
High-throughput structure-based pharmacophore modelling as a basis for successful parallel virtual screening
-
Steindl, T.M.; Schuster, D.; Wolber, G.; Laggner, C.; Langer, T. High-throughput structure-based pharmacophore modelling as a basis for successful parallel virtual screening. J. Comput. Aided Mol. Des. 2006, 20, 703-715.
-
(2006)
J. Comput. Aided Mol. Des.
, vol.20
, pp. 703-715
-
-
Steindl, T.M.1
Schuster, D.2
Wolber, G.3
Laggner, C.4
Langer, T.5
-
195
-
-
79957946803
-
Pharmacophore modelling: A forty year old approach and its modern synergies
-
Caporuscio, F.; Tafi, A. Pharmacophore modelling: A forty year old approach and its modern synergies. Curr. Med. Chem. 2011, 18, 2543-2553.
-
(2011)
Curr. Med. Chem.
, vol.18
, pp. 2543-2553
-
-
Caporuscio, F.1
Tafi, A.2
-
196
-
-
84861189353
-
Inverse virtual screening allows the discovery of the biological activity of natural compounds
-
Lauro, G.; Masullo, M.; Piacente, S.; Riccio, R.; Bifulco, G. Inverse Virtual Screening allows the discovery of the biological activity of natural compounds. Bioorg. Med. Chem. 2012, 20, 3596-3602.
-
(2012)
Bioorg. Med. Chem.
, vol.20
, pp. 3596-3602
-
-
Lauro, G.1
Masullo, M.2
Piacente, S.3
Riccio, R.4
Bifulco, G.5
-
197
-
-
79959699687
-
Inverse virtual screening of antitumor targets: Pilot study on a small database of natural bioactive compounds
-
Lauro, G.; Romano, A.; Riccio, R.; Bifulco, G. Inverse virtual screening of antitumor targets: Pilot study on a small database of natural bioactive compounds. J. Nat. Prod. 2011, 74, 1401-1407.
-
(2011)
J. Nat. Prod.
, vol.74
, pp. 1401-1407
-
-
Lauro, G.1
Romano, A.2
Riccio, R.3
Bifulco, G.4
-
198
-
-
84903286855
-
Facing the challenges of structure-based target prediction by inverse virtual screening
-
Schomburg, K.T.; Bietz, S.; Briem, H.; Henzler, A.M.; Urbaczek, S.; Rarey, M. Facing the challenges of structure-based target prediction by inverse virtual screening. J. Chem. Inf. Model. 2014, 54, 1676-1686.
-
(2014)
J. Chem. Inf. Model.
, vol.54
, pp. 1676-1686
-
-
Schomburg, K.T.1
Bietz, S.2
Briem, H.3
Henzler, A.M.4
Urbaczek, S.5
Rarey, M.6
|