Macromolecular bases of antischistosomal therapy

Current Topics in Medicinal Chemistry

Volumn 11, Issue 16, 2011, Pages 2012-2028

  Angelucci, Francesco ^a   Miele, Adriana Erica ^a   Boumis, Giovanna ^a   Brunori, Maurizio ^a   Dimastrogiovanni, Daniela ^a   Bellelli, Andrea ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Artemisinin; Auranofin; Crystal structure; Neglected tropical disease; Oxamniquine; Praziquantel; Proteases; Schistosomiasis; Thioredoxin glutathione reductase

Indexed keywords

6 PHOSPHOFRUCTOKINASE; ACETYLCHOLINESTERASE; ANTIMONY TARTRATE; ANTISCHISTOSOMAL AGENT; ARTEMETHER; ARTEMISININ; ARTESUNATE; AURANOFIN; CHLOROQUINE; CLONAZEPAM; CYCLOPHILIN; CYCLOSPORIN A; FUROXANE DERIVATIVE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; HYCANTHONE; K 11777; MECLONAZEPAM; MEFLOQUINE; METRIFONATE; OLTIPRAZ; OXADIAZOLE DERIVATIVE; OXAMNIQUINE; PEROXIREDOXIN; PRAZIQUANTEL; PROTEINASE; PURINE NUCLEOSIDE PHOSPHORYLASE; THIOREDOXIN GLUTATHIONE REDUCTASE; TRIOXOLANE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VOLTAGE GATED CALCIUM CHANNEL;

AMINO ACID SEQUENCE; BINDING AFFINITY; CALCIUM CURRENT; DRUG BINDING SITE; DRUG DESIGN; DRUG MECHANISM; DRUG SENSITIVITY; DRUG STRUCTURE; DRUG TARGETING; ENZYME ACTIVE SITE; ENZYME MECHANISM; ENZYME STRUCTURE; GENOME ANALYSIS; HUMAN; MACROMOLECULE; MALARIA; NONHUMAN; NUCLEOTIDE SEQUENCE; REVIEW; SCHISTOSOMA HEMATOBIUM; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS; SEQUENCE HOMOLOGY; SINGLE DRUG DOSE; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION; UNSPECIFIED SIDE EFFECT;

ACETYLCHOLINESTERASE; ANIMALS; AURANOFIN; CRYSTALLOGRAPHY, X-RAY; CYCLOPHILINS; DRUG DESIGN; ENZYME INHIBITORS; GLUTATHIONE PEROXIDASE; HUMANS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR TARGETED THERAPY; MULTIENZYME COMPLEXES; NADH, NADPH OXIDOREDUCTASES; PEPTIDE HYDROLASES; PEROXIREDOXINS; PRAZIQUANTEL; PURINE-NUCLEOSIDE PHOSPHORYLASE; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS; SCHISTOSOMICIDES;

EID: 80051690024     PISSN: 15680266     EISSN: 18734294     Source Type: Journal    
DOI: 10.2174/156802611796575939     Document Type: Review

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