In vivo effect of single oral dose of artemether against early juvenile stages of Schistosoma mansoni Egyptian strain

Experimental Parasitology

Volumn 135, Issue 2, 2013, Pages 240-245

  El Beshbishi, Samar N ^a   Taman, Amira ^a   El Malky, Mohamed ^a,b   Azab, Manar S ^a   El Hawary, Amira K ^a   El Tantawy, Dina A ^a  

^a MANSOURA UNIVERSITY   (Egypt)

^b UMM AL QURA UNIVERSITY   (Saudi Arabia)

Author keywords

Artemether; Histopathological study; Juvenile stages; Schistosoma mansoni; Schistosomula; Worm burden

Indexed keywords

ARTEMETHER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTHELMINTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DOSAGE SCHEDULE COMPARISON; DRUG EFFICACY; EGG LAYING; FEMALE; IN VIVO STUDY; INFECTION SENSITIVITY; LARVAL DEVELOPMENT; LIVER GRANULOMA; MORBIDITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS MANSONI; SINGLE DRUG DOSE; TYPE STRAIN;

ARTEMETHER; HISTOPATHOLOGICAL STUDY; JUVENILE STAGES; SCHISTOSOMA MANSONI; SCHISTOSOMULA; WORM BURDEN;

ADMINISTRATION, ORAL; ANIMALS; ARTEMISININS; BIOMPHALARIA; FEMALE; LIVER; MICE; MICE, INBRED BALB C; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS MANSONI; SCHISTOSOMICIDES;

EID: 84882239760     PISSN: 00144894     EISSN: 10902449     Source Type: Journal    
DOI: 10.1016/j.exppara.2013.07.006     Document Type: Article

References (41)

1. Abdul-Ghani R., Loutfy N., Sheta M. Artemether shows promising female schistosomicidal and ovicidal effects on the Egyptian strain of Schistosoma mansoni after maturity of infection. Parasitology Research 2011, 108:1199-1205.
2. Abdulla M.H., Lim K.C., Sajid M., McKerrow J.H., Caffrey C.R. Schistosomiasis mansoni: novel chemotherapy using a cysteine protease inhibitor. PLoS Medicine 2007, 4:e14.
3. Bergquist R., Utzinger J., Cholett J., Xiao S.H., Weiss N.A., Tanner M. Triggering of high-level resistance against Schistosoma mansoni reinfection by artemether in the mouse model. American Journal of Tropical Medicine and Hygiene 2004, 71:774-777.
4. Botros S.S., Bennett J.L. Praziquantel resistance. Expert Opinion on Drug Discovery 2007, 2:35-40.
5. Botros S.S., Mahmoud M.R., Moussa M.M., Nosseir M.M. Immunohistopathological and biochemical changes in Schistosoma mansoni-infected mice treated with artemether. Journal of Infection 2007, 55:470-477.
6. Botros S.S., Hammam O., Mahmoud M., Bergquist R. Praziquantel efficacy in mice infected with PZQ non-susceptible S. mansoni isolate treated with artemether: parasitological, biochemical and immunohistochemical assessment. APMIS 2010, 118:692-702.
7. Caffrey C.R., Secor W.E. Schistosomiasis: from drug deployment to drug development. Current Opinion in Infectious Diseases 2011, 24:410-417.
8. Cheever A.W. Conditions affecting the accuracy of potassium hydroxide digestion techniques for counting Schistosoma mansoni eggs in tissues. Bulletin of the World Health Organization 1968, 39:328-331.
9. Cioli D., Pica-Mattoccia L. Praziquantel. Parasitology Research 2003, 90:S3-S9.
10. Doenhoff M.J., Cioli D., Utzinger J. Praziquantel: mechanisms of action, resistance and new derivatives for schistosomiasis. Current Opinion in Infectious Diseases 2008, 21:659-667.
11. El-Beshbishi S.N., Taman A., El-Malky M.A., Azab M.S., El-Hawary A.K., El-Tantawy D.A. First insight into the effect of single oral dose therapy with artemisinin-naphthoquine phosphate combination in a mouse model of Schistosoma mansoni infection. International Journal of Parasitology 2013, 43(7):521-530.
12. El-Lakkany N.M., Seif el-Din S.H., Badawy A.A., Ebeid F.A. Effect of artemether alone and in combination with grapefruit juice on hepatic drug-metabolising enzymes and biochemical aspects in experimental Schistosoma mansoni. International Journal of Parasitology 2004, 34:1405-1412.
13. El-Lakkany N.M., Seif El-Din S.H. Haemin enhances the in vivo efficacy of artemether against juvenile and adult Schistosoma mansoni in mice. Parasitology Research 2013, 112(5):2005-2015.
14. Fallon P.G., Doenhoff M.J. Drug-resistant schistosomiasis: resistance to praziquantel and oxamniquine induced in Schistosoma mansoni in mice is drug specific. American Journal of Tropical Medicine and Hygiene 1994, 51:83-88.
15. Golenser J., Waknine J.H., Krugliak M., Hunt N.H., Grau G.E. Current perspectives on the mechanism of action of artemisinins. International Journal of Parasitology 2006, 36:1427-1441.
16. Gray D.J., McManus D.P., Li Y., Williams G.M., Bergquist R., Ross A.G. Schistosomiasis elimination: lessons from the past guide the future. The Lancet Infectious Diseases 2010, 10:733-736.
17. Gryseels B., Mbaye A., De Vlas S.J., Stelma F.F., Guissé F., van Lieshout L., Faye D., Diop M., Ly A., Tchuem-Tchuenté L.A., Engels D., Polman K. Are poor responses to praziquantel for the treatment of Schistosoma mansoni infections in Senegal due to resistance? An overview of the evidence. Tropical Medicine and International Health 2001, 6:864-873.
18. Ismail M., Botros S., Metwally A., William S., Farghaly A., Tao L.F., Day T.A., Bennett J.L. Resistance to praziquantel: direct evidence from Schistosoma mansoni isolated from Egyptian villagers. American Journal of Tropical Medicine and Hygiene 1999, 60:932-935.
19. Keiser J., Vargas M., Doenhoff M.J. Activity of artemether and mefloquine against juvenile and adult Schistosoma mansoni in athymic and immunocompetent NMRI mice. American Journal of Tropical Medicine and Hygiene 2010, 82(1):112-114.
20. Lawn S.D., Lucas S.B., Chiodini P.L. Case report: Schistosoma mansoni infection: failure of standard treatment with praziquantel in a returned traveler. Transactions of the Royal Society of Tropical Medicine and Hygiene 2003, 97:100-101.
21. Lescano S.Z., Chieffi P.P., Canhassi R.R., Boulos M., Amato Neto N. Antischistosomal activity of artemether in experimental Schistosomiasis mansoni. Revista de Saúde Pública 2004, 38(1):71-75.
22. Li H.J., Wang W., Li Y.Z., Qu G.L., Xing Y.T., Tao Y.H., Wei J.Y., Dai J.R., Liang Y.S. Effects of artemether, artesunate and dihydroartemisinin administered orally at multiple doses or combination in treatment of mice infected with Schistosoma japonicum. Parasitology Research 2011, 109:515-519.
23. Lichtenberg V.F. Host response to eggs of S. manosni I. Granuloma formation in the unsensitized laboratory mouse. American Journal of Pathology 1962, 41:711-731.
24. Mahmoud M.R., Botros S.S. Artemether as adjuvant therapy to praziquantel in murine Egyptian schistosomiasis mansoni. Journal of Parasitology 2005, 91(1):175-178.
25. Nare B., Smith J.M., Prichard R.K. Schistosoma mansoni: levels of antioxidants and resistance to oxidants increase during development. Experimental Parasitology 1990, 70:389-397.
26. Pellegrino J., Oliveira C.A., Faria J., Cunha A. New approach to the screening of drugs in experimental Schistosoma mansoni in mice. American Journal of Tropical Medicine and Hygiene 1962, 11:201-215.
27. Pérez del Villar L., Burguillo F.J., López-Abán J., Muro A. Systematic review and meta-analysis of artemisinin based therapies for the treatment and prevention of schistosomiasis. PLoS One 2012, 7(9):e45867.
28. Picquet M., Vercruysse J., Shaw D.J., Diop M., Ly A. Efficacy of praziquantel against Schistosoma mansoni in northern Senegal. Transactions of the Royal Society of Tropical Medicine and Hygiene 1998, 92:90-93.
29. Sayed A.A., Simeonov A., Thomas C.J., Inglese J., Austin C.P., Williams D.L. Identification of oxadiazoles as new drug leads for the control of schistosomiasis. Nature Medicine 2008, 14:407-412.
30. Seif el-Din S.H., Al-Hroob A.M., Ebeid F.A. Schistosoma mansoni: N-acetylcysteine downregulates oxidative stress and enhances the antischistosomal activity of artemether in mice. Experimental Parasitology 2011, 128(3):230-235.
31. Smithers S.R., Terry R.T. Infection of laboratory hosts with cercariae ofSchistosoma mansoni and the recovery of adult worms. Parasitology 1965, 55:695-700.
32. Utzinger J., Xiao S.H., N'Goran E.K., Bergquist R., Tanner M. The potential of artemether for the control of schistosomiasis. International Journal of Parasitology 2001, 31:1549-1562.
33. Utzinger J., Chollet J., Tu Z., Xiao S.H., Tanner M. Comparative study of the effects of artemether and artesunate on juvenile and adult Schistosoma mansoni in experimentally infected mice. Transactions of the Royal Society of Tropical Medicine and Hygiene 2002, 96:318-323.
34. Utzinger J., Xiao S.H., Tanner M., Keiser J. Artemisinins for schistosomiasis and beyond. Current Opinion in Investigational Drugs 2007, 8(2):105-116.
35. Wang W., Dai J.R., Li H.J., Shen X.H., Liang Y.S. Is there reduced susceptibility to praziquantel in Schistosoma japonicum? Evidence from China. Parasitology 2010, 137:1905-1912.
36. Xiao S., Catto B.A. In vitro and in vivo studies of the effect of artemether on Schistosoma mansoni. Antimicrobial Agents and Chemotherapy 1989, 33:1557-1562.
37. Xiao S.H., Booth M., Tanner M. The prophylactic effects of artemether against Schistosoma japonicum infections. Parasitology Today 2000, 16:122-126.
38. Xiao S.H., Chollet J., Weiss N.A., Bergquist R.N., Tanner M. Preventive effect of artemether in experimental animals infected with Schistosoma mansoni. Parasitology International 2000, 49:19-24.
39. Xiao S.H., Chollet J., Utzinger J., Matile H., Mei J., Tanner M. Artemether administered together with haemin damages schistosomes in vitro. Transactions of the Royal Society of Tropical Medicine and Hygiene 2001, 95:67-71.
40. Xiao S.H., Utzinger J., Chollet J., Tanner M. Effect of artemether administered alone or in combination with praziquantel to mice infected with Plasmodium berghei or Schistosoma mansoni or both. International Journal of Parasitology 2006, 36:957-964.
41. Zhai Z.L., Jiao P.Y., Mei J.Y., Xiao S.H. Glutathione inhibits the antischistosomal activity of artemether. Chinese Journal of Parasitology and Parasitic Diseases 2002, 20:212-215.