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Volumn 133, Issue 6, 2013, Pages 1629-1637

Autophagy is induced by UVA and promotes removal of oxidized phospholipids and protein aggregates in epidermal keratinocytes

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; BETA ACTIN; PALMITIC ACID; PHOSPHOLIPID; PROTEIN; PROTEIN P62; RAPAMYCIN; SINGLET OXYGEN; STEARIC ACID; TRANSCRIPTION FACTOR NRF2;

EID: 84878544117     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2013.26     Document Type: Article
Times cited : (121)

References (53)
  • 1
    • 0038206735 scopus 로고    scopus 로고
    • Formation of apolipoprotein AIphosphatidylcholine core aldehyde Schiff base adducts promotes uptake by THP-1 macrophages
    • Ahmed Z, Ravandi A, Maguire GF et al. (2003) Formation of apolipoprotein AIphosphatidylcholine core aldehyde Schiff base adducts promotes uptake by THP-1 macrophages. Cardiovasc Res 58:712-20
    • (2003) Cardiovasc Res , vol.58 , pp. 712-720
    • Ahmed, Z.1    Ravandi, A.2    Maguire, G.F.3
  • 2
    • 27944504351 scopus 로고    scopus 로고
    • P62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on Huntingtin-induced cell death
    • Bjorkoy G, Lamark T, Brech A et al. (2005) p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on Huntingtin-induced cell death. J Cell Biol 171:603-14
    • (2005) J Cell Biol , vol.171 , pp. 603-614
    • Bjorkoy, G.1    Lamark, T.2    Brech, A.3
  • 3
    • 77949618571 scopus 로고    scopus 로고
    • Generation and biological activities of oxidized phospholipids
    • Bochkov VN, Oskolkova OV, Birukov KG et al. (2010) Generation and biological activities of oxidized phospholipids. Antioxid Redox Signal 12:1009-59
    • (2010) Antioxid Redox Signal , vol.12 , pp. 1009-1059
    • Bochkov, V.N.1    Oskolkova, O.V.2    Birukov, K.G.3
  • 4
    • 0036591860 scopus 로고    scopus 로고
    • Impairment of proteasome function upon UVA- and UVB-irradiation of human keratinocytes
    • Bulteau AL, Moreau M, Nizard C et al. (2002) Impairment of proteasome function upon UVA- and UVB-irradiation of human keratinocytes. Free Radic Biol Med 32:1157-70
    • (2002) Free Radic Biol Med , vol.32 , pp. 1157-1170
    • Bulteau, A.L.1    Moreau, M.2    Nizard, C.3
  • 5
    • 0031569876 scopus 로고    scopus 로고
    • Diminished susceptibility to proteolysis after protein modification by the lipid peroxidation product malondialdehyde: Inhibitory role for crosslinked and noncrosslinked adducted proteins
    • Burcham PC, Kuhan YT (1997) Diminished susceptibility to proteolysis after protein modification by the lipid peroxidation product malondialdehyde: inhibitory role for crosslinked and noncrosslinked adducted proteins. Arch Biochem Biophys 340:331-7
    • (1997) Arch Biochem Biophys , vol.340 , pp. 331-337
    • Burcham, P.C.1    Kuhan, Y.T.2
  • 6
    • 33947606911 scopus 로고    scopus 로고
    • Nitrosative stress, cellular stress response, and thiol homeostasis in patients with Alzheimer's disease
    • Calabrese V, Sultana R, Scapagnini G et al. (2006) Nitrosative stress, cellular stress response, and thiol homeostasis in patients with Alzheimer's disease. Antioxid Redox Signal 8:1975-86
    • (2006) Antioxid Redox Signal , vol.8 , pp. 1975-1986
    • Calabrese, V.1    Sultana, R.2    Scapagnini, G.3
  • 7
    • 67650376373 scopus 로고    scopus 로고
    • Oxidized proteins: Mechanisms of removal and consequences of accumulation
    • Dunlop RA, Brunk UT, Rodgers KJ (2009) Oxidized proteins: mechanisms of removal and consequences of accumulation. IUBMB Life 61:522-7
    • (2009) IUBMB Life , vol.61 , pp. 522-527
    • Dunlop, R.A.1    Brunk, U.T.2    Rodgers, K.J.3
  • 8
    • 0025814980 scopus 로고
    • Chemistry and biochemistry of 4- hydroxynonenal, malonaldehyde and related aldehydes
    • Esterbauer H, Schaur RJ, Zollner H (1991) Chemistry and biochemistry of 4- hydroxynonenal, malonaldehyde and related aldehydes. Free Radic Biol Med 11:81-128
    • (1991) Free Radic Biol Med , vol.11 , pp. 81-128
    • Esterbauer, H.1    Schaur, R.J.2    Zollner, H.3
  • 9
    • 3142721782 scopus 로고    scopus 로고
    • Induction of phase 2 genes by sulforaphane protects retinal pigment epithelial cells against photooxidative damage
    • Gao X, Talalay P (2004) Induction of phase 2 genes by sulforaphane protects retinal pigment epithelial cells against photooxidative damage. Proc Natl Acad Sci USA 101:10446-51
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 10446-10451
    • Gao, X.1    Talalay, P.2
  • 11
    • 84861434263 scopus 로고    scopus 로고
    • A simplified procedure for semi-targeted lipidomic analysis of oxidized phosphatidylcholines induced by UVA irradiation
    • Gruber F, Bicker W, Oskolkova OV et al. (2012) A simplified procedure for semi-targeted lipidomic analysis of oxidized phosphatidylcholines induced by UVA irradiation. J Lipid Res 53:1232-42
    • (2012) J Lipid Res , vol.53 , pp. 1232-1242
    • Gruber, F.1    Bicker, W.2    Oskolkova, O.V.3
  • 12
    • 75149178692 scopus 로고    scopus 로고
    • NF-E2-related factor 2 regulates the stress response to UVA-1-oxidized phospholipids in skin cells
    • Gruber F, Mayer H, Lengauer B et al. (2010) NF-E2-related factor 2 regulates the stress response to UVA-1-oxidized phospholipids in skin cells. FASEB J 24:39-48
    • (2010) FASEB J , vol.24 , pp. 39-48
    • Gruber, F.1    Mayer, H.2    Lengauer, B.3
  • 13
    • 34447118187 scopus 로고    scopus 로고
    • Photooxidation generates biologically active phospholipids that induce heme oxygenase-1 in skin cells
    • Gruber F, Oskolkova O, Leitner A et al. (2007) Photooxidation generates biologically active phospholipids that induce heme oxygenase-1 in skin cells. J Biol Chem 282:16934-41
    • (2007) J Biol Chem , vol.282 , pp. 16934-16941
    • Gruber, F.1    Oskolkova, O.2    Leitner, A.3
  • 14
    • 0041669528 scopus 로고    scopus 로고
    • The proteasomal system and HNE-modified proteins
    • Grune T, Davies KJ (2003) The proteasomal system and HNE-modified proteins. Mol Aspects Med 24:195-204
    • (2003) Mol Aspects Med , vol.24 , pp. 195-204
    • Grune, T.1    Davies, K.J.2
  • 15
    • 0038627633 scopus 로고    scopus 로고
    • Oxidatively truncated docosahexaenoate phospholipids: Total synthesis, generation, and Peptide adduction chemistry
    • Gu X, Sun M, Gugiu B et al. (2003) Oxidatively truncated docosahexaenoate phospholipids: total synthesis, generation, and Peptide adduction chemistry. J Org Chem 68:3749-61
    • (2003) J Org Chem , vol.68 , pp. 3749-3761
    • Gu, X.1    Sun, M.2    Gugiu, B.3
  • 16
    • 33644530052 scopus 로고    scopus 로고
    • Identification of oxidatively truncated ethanolamine phospholipids in retina and their generation from polyunsaturated phosphatidylethanolamines
    • Gugiu BG, Mesaros CA, Sun M et al. (2006) Identification of oxidatively truncated ethanolamine phospholipids in retina and their generation from polyunsaturated phosphatidylethanolamines. Chem Res Toxicol 19:262-71
    • (2006) Chem Res Toxicol , vol.19 , pp. 262-271
    • Gugiu, B.G.1    Mesaros, C.A.2    Sun, M.3
  • 17
    • 78650650238 scopus 로고    scopus 로고
    • Intensity-dependent direct solar radiation- and UVA-induced radical damage to human skin and DNA, lipids and proteins
    • Haywood R, Andrady C, Kassouf N et al. (2011) Intensity-dependent direct solar radiation- and UVA-induced radical damage to human skin and DNA, lipids and proteins. Photochem Photobiol 87:117-30
    • (2011) Photochem Photobiol , vol.87 , pp. 117-130
    • Haywood, R.1    Andrady, C.2    Kassouf, N.3
  • 18
    • 16844375366 scopus 로고    scopus 로고
    • Ultraviolet A irradiation induces NFE2- related factor 2 activation in dermal fibroblasts: Protective role in UVA-induced apoptosis
    • Hirota A, Kawachi Y, Itoh K et al. (2005) Ultraviolet A irradiation induces NFE2- related factor 2 activation in dermal fibroblasts: protective role in UVA-induced apoptosis. J Invest Dermatol 124:825-32
    • (2005) J Invest Dermatol , vol.124 , pp. 825-832
    • Hirota, A.1    Kawachi, Y.2    Itoh, K.3
  • 19
    • 79551468720 scopus 로고    scopus 로고
    • Inducible disruption of autophagy in the lung causes airway hyper-responsiveness
    • Inoue D, Kubo H, Taguchi K et al. (2011) Inducible disruption of autophagy in the lung causes airway hyper-responsiveness. Biochem Biophys Res Commun 405:13-8
    • (2011) Biochem Biophys Res Commun , vol.405 , pp. 13-18
    • Inoue, D.1    Kubo, H.2    Taguchi, K.3
  • 20
    • 77954599053 scopus 로고    scopus 로고
    • P62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription
    • Jain A, Lamark T, Sjottem E et al. (2010) p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription. J Biol Chem 285:22576-91
    • (2010) J Biol Chem , vol.285 , pp. 22576-22591
    • Jain, A.1    Lamark, T.2    Sjottem, E.3
  • 21
    • 84862295360 scopus 로고    scopus 로고
    • Guidelines for the use and interpretation of assays for monitoring autophagy
    • Klionsky DJ, Abdalla FC, Abeliovich H et al. (2012) Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 8:445-544
    • (2012) Autophagy , vol.8 , pp. 445-544
    • Klionsky, D.J.1    Abdalla, F.C.2    Abeliovich, H.3
  • 22
    • 77649265091 scopus 로고    scopus 로고
    • The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1
    • Komatsu M, Kurokawa H, Waguri S et al. (2010) The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1. Nat Cell Biol 12:213-23
    • (2010) Nat Cell Biol , vol.12 , pp. 213-223
    • Komatsu, M.1    Kurokawa, H.2    Waguri, S.3
  • 23
    • 21044455137 scopus 로고    scopus 로고
    • Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice
    • Komatsu M, Waguri S, Ueno T et al. (2005) Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice. J Cell Biol 169:425-34
    • (2005) J Cell Biol , vol.169 , pp. 425-434
    • Komatsu, M.1    Waguri, S.2    Ueno, T.3
  • 24
    • 55549101910 scopus 로고    scopus 로고
    • Oxidized glycerophosphocholines as biologically active mediators for ultraviolet radiation-mediated effects
    • Konger RL, Marathe GK, Yao Y et al. (2008) Oxidized glycerophosphocholines as biologically active mediators for ultraviolet radiation-mediated effects. Prostaglandins Other Lipid Mediat 87:1-8
    • (2008) Prostaglandins Other Lipid Mediat , vol.87 , pp. 1-8
    • Konger, R.L.1    Marathe, G.K.2    Yao, Y.3
  • 25
    • 84856814862 scopus 로고    scopus 로고
    • Sun exposure: What molecular photodermatology tells us about its good and bad sides
    • Krutmann J, Morita A, Chung JH (2012) Sun exposure: what molecular photodermatology tells us about its good and bad sides. J Invest Dermatol 132:976-84
    • (2012) J Invest Dermatol , vol.132 , pp. 976-984
    • Krutmann, J.1    Morita, A.2    Chung, J.H.3
  • 26
    • 77958151524 scopus 로고    scopus 로고
    • The malondialdehyde-derived fluorophore DHP-lysine is a potent sensitizer of UVA-induced photooxidative stress in human skin cells
    • Lamore SD, Azimian S, Horn D et al. (2010) The malondialdehyde-derived fluorophore DHP-lysine is a potent sensitizer of UVA-induced photooxidative stress in human skin cells. J Photochem Photobiol B 101:251-64
    • (2010) J Photochem Photobiol B , vol.101 , pp. 251-264
    • Lamore, S.D.1    Azimian, S.2    Horn, D.3
  • 27
    • 84255197201 scopus 로고    scopus 로고
    • Autophagic-lysosomal dysregulation downstream of cathepsin B inactivation in human skin fibroblasts exposed to UVA
    • Lamore SD, Wondrak GT (2012) Autophagic-lysosomal dysregulation downstream of cathepsin B inactivation in human skin fibroblasts exposed to UVA. Photochem Photobiol Sci 11:163-72
    • (2012) Photochem Photobiol Sci , vol.11 , pp. 163-172
    • Lamore, S.D.1    Wondrak, G.T.2
  • 28
    • 79251589356 scopus 로고    scopus 로고
    • Autophagy negatively regulates keratinocyte inflammatory responses via scaffolding protein p62/SQSTM1
    • Lee HM, Shin DM, Yuk JM et al. (2011) Autophagy negatively regulates keratinocyte inflammatory responses via scaffolding protein p62/SQSTM1. J Immunol 186:1248-58
    • (2011) J Immunol , vol.186 , pp. 1248-1258
    • Lee, H.M.1    Shin, D.M.2    Yuk, J.M.3
  • 29
    • 33947164292 scopus 로고    scopus 로고
    • OKL38 is an oxidative stress response gene stimulated by oxidized phospholipids
    • Li R, Chen W, Yanes R et al. (2007) OKL38 is an oxidative stress response gene stimulated by oxidized phospholipids. J Lipid Res 48:709-15
    • (2007) J Lipid Res , vol.48 , pp. 709-715
    • Li, R.1    Chen, W.2    Yanes, R.3
  • 30
    • 36249025723 scopus 로고    scopus 로고
    • Autophagy: Process and function
    • Mizushima N (2007) Autophagy: process and function. Genes Dev 21: 2861-73
    • (2007) Genes Dev , vol.21 , pp. 2861-2873
    • Mizushima, N.1
  • 31
    • 1542283812 scopus 로고    scopus 로고
    • In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker
    • Mizushima N, Yamamoto A, Matsui M et al. (2004) In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker. Mol Biol Cell 15:1101-11
    • (2004) Mol Biol Cell , vol.15 , pp. 1101-1111
    • Mizushima, N.1    Yamamoto, A.2    Matsui, M.3
  • 32
    • 75749122303 scopus 로고    scopus 로고
    • Methods in mammalian autophagy research
    • Mizushima N, Yoshimori T, Levine B (2010) Methods in mammalian autophagy research. Cell 140:313-26
    • (2010) Cell , vol.140 , pp. 313-326
    • Mizushima, N.1    Yoshimori, T.2    Levine, B.3
  • 33
    • 78149476302 scopus 로고    scopus 로고
    • Identification of an autophagy defect in smokers' alveolar macrophages
    • Monick MM, Powers LS, Walters K et al. (2010) Identification of an autophagy defect in smokers' alveolar macrophages. J Immunol 185: 5425-35
    • (2010) J Immunol , vol.185 , pp. 5425-5435
    • Monick, M.M.1    Powers, L.S.2    Walters, K.3
  • 34
    • 0026443725 scopus 로고
    • Non-cyclooxygenase-derived prostanoids (F2-isoprostanes) are formed in situ on phospholipids
    • Morrow JD, Awad JA, Boss HJ et al. (1992) Non-cyclooxygenase-derived prostanoids (F2-isoprostanes) are formed in situ on phospholipids. Proc Natl Acad Sci USA 89:10721-5
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 10721-10725
    • Morrow, J.D.1    Awad, J.A.2    Boss, H.J.3
  • 35
    • 79952080909 scopus 로고    scopus 로고
    • Recent progress in phospholipase A(2) research: From cells to animals to humans
    • Murakami M, Taketomi Y, Miki Y et al. (2011) Recent progress in phospholipase A(2) research: from cells to animals to humans. Prog Lipid Res 50:152-92
    • (2011) Prog Lipid Res , vol.50 , pp. 152-192
    • Murakami, M.1    Taketomi, Y.2    Miki, Y.3
  • 36
    • 77956574773 scopus 로고    scopus 로고
    • Pathological aspects of lipid peroxidation
    • Negre-Salvayre A, Auge N, Ayala V et al. (2010) Pathological aspects of lipid peroxidation. Free Radic Res 44:1125-71
    • (2010) Free Radic Res , vol.44 , pp. 1125-1171
    • Negre-Salvayre, A.1    Auge, N.2    Ayala, V.3
  • 37
    • 34548259958 scopus 로고    scopus 로고
    • P62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy
    • Pankiv S, Clausen TH, Lamark T et al. (2007) p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy. J Biol Chem 282:24131-45
    • (2007) J Biol Chem , vol.282 , pp. 24131-24145
    • Pankiv, S.1    Clausen, T.H.2    Lamark, T.3
  • 38
    • 0037064120 scopus 로고    scopus 로고
    • Identification of a novel family of oxidized phospholipids that serve as ligands for the macrophage scavenger receptor CD36
    • Podrez EA, Poliakov E, Shen Z et al. (2002) Identification of a novel family of oxidized phospholipids that serve as ligands for the macrophage scavenger receptor CD36. J Biol Chem 277:38503-16
    • (2002) J Biol Chem , vol.277 , pp. 38503-38516
    • Podrez, E.A.1    Poliakov, E.2    Shen, Z.3
  • 39
    • 0021305332 scopus 로고
    • Chemistry of lipid peroxidation
    • Porter NA (1984) Chemistry of lipid peroxidation. Methods Enzymol 105:273-82
    • (1984) Methods Enzymol , vol.105 , pp. 273-282
    • Porter, N.A.1
  • 40
    • 80052261937 scopus 로고    scopus 로고
    • Lipid peroxidation and neurodegenerative disease
    • Reed TT (2011) Lipid peroxidation and neurodegenerative disease. Free Radic Biol Med 51:1302-19
    • (2011) Free Radic Biol Med , vol.51 , pp. 1302-1319
    • Reed, T.T.1
  • 41
    • 78049495046 scopus 로고    scopus 로고
    • Ubiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway: A potential role for protein aggregation in autophagic substrate selection
    • Riley BE, Kaiser SE, Shaler TA et al. (2010) Ubiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway: a potential role for protein aggregation in autophagic substrate selection. J Cell Biol 191:537-52
    • (2010) J Cell Biol , vol.191 , pp. 537-552
    • Riley, B.E.1    Kaiser, S.E.2    Shaler, T.A.3
  • 42
    • 2442636729 scopus 로고    scopus 로고
    • Loss of vascular endothelial growth factor a activity in murine epidermal keratinocytes delays wound healing and inhibits tumor formation
    • Rossiter H, Barresi C, Pammer J et al. (2004) Loss of vascular endothelial growth factor a activity in murine epidermal keratinocytes delays wound healing and inhibits tumor formation. Cancer Res 64:3508-16
    • (2004) Cancer Res , vol.64 , pp. 3508-3516
    • Rossiter, H.1    Barresi, C.2    Pammer, J.3
  • 43
    • 33750363298 scopus 로고    scopus 로고
    • The roles of intracellular protein-degradation pathways in neurodegeneration
    • Rubinsztein DC (2006) The roles of intracellular protein-degradation pathways in neurodegeneration. Nature 443:780-6
    • (2006) Nature , vol.443 , pp. 780-786
    • Rubinsztein, D.C.1
  • 44
    • 0033929845 scopus 로고    scopus 로고
    • HNE-derived 2-pentylpyrroles are generated during oxidation of LDL, are more prevalent in blood plasma from patients with renal disease or atherosclerosis, and are present in atherosclerotic plaques
    • Salomon RG, Kaur K, Podrez E et al. (2000) HNE-derived 2-pentylpyrroles are generated during oxidation of LDL, are more prevalent in blood plasma from patients with renal disease or atherosclerosis, and are present in atherosclerotic plaques. Chem Res Toxicol 13:557-64
    • (2000) Chem Res Toxicol , vol.13 , pp. 557-564
    • Salomon, R.G.1    Kaur, K.2    Podrez, E.3
  • 45
    • 0036223839 scopus 로고    scopus 로고
    • Photoaging is associated with protein oxidation in human skin in vivo
    • Sander CS, Chang H, Salzmann S et al. (2002) Photoaging is associated with protein oxidation in human skin in vivo. J Invest Dermatol 118:618-25
    • (2002) J Invest Dermatol , vol.118 , pp. 618-625
    • Sander, C.S.1    Chang, H.2    Salzmann, S.3
  • 46
    • 84860530952 scopus 로고    scopus 로고
    • Nrf2 links epidermal barrier function with antioxidant defense
    • Schafer M, Farwanah H, Willrodt AH et al. (2012) Nrf2 links epidermal barrier function with antioxidant defense. EMBO Mol Med 4:364-79
    • (2012) EMBO Mol Med , vol.4 , pp. 364-379
    • Schafer, M.1    Farwanah, H.2    Willrodt, A.H.3
  • 47
    • 65949095803 scopus 로고    scopus 로고
    • Autophagy regulates lipid metabolism
    • Singh R, Kaushik S, Wang Y et al. (2009) Autophagy regulates lipid metabolism. Nature 458:1131-5
    • (2009) Nature , vol.458 , pp. 1131-1135
    • Singh, R.1    Kaushik, S.2    Wang, Y.3
  • 48
    • 84862490479 scopus 로고    scopus 로고
    • Autophagy in the thymic epithelium is dispensable for the development of self-tolerance in a novel mouse model
    • Sukseree S, Mildner M, Rossiter H et al. (2012) Autophagy in the thymic epithelium is dispensable for the development of self-tolerance in a novel mouse model. PLoS One 7:e38933
    • (2012) PLoS One , vol.7
    • Sukseree, S.1    Mildner, M.2    Rossiter, H.3
  • 49
    • 84865287281 scopus 로고    scopus 로고
    • Keap1 degradation by autophagy for the maintenance of redox homeostasis
    • Taguchi K, Fujikawa N, Komatsu M et al. (2012) Keap1 degradation by autophagy for the maintenance of redox homeostasis. Proc Natl Acad Sci USA 109:13561-6
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 13561-13566
    • Taguchi, K.1    Fujikawa, N.2    Komatsu, M.3
  • 50
    • 84863986254 scopus 로고    scopus 로고
    • The innate immune response to products of phospholipid peroxidation
    • Weismann D, Binder CJ (2012) The innate immune response to products of phospholipid peroxidation. Biochim Biophys Acta 1818:2465-75
    • (2012) Biochim Biophys Acta , vol.1818 , pp. 2465-2475
    • Weismann, D.1    Binder, C.J.2
  • 51
    • 8544263882 scopus 로고    scopus 로고
    • Overexpression of phospholipidhydroperoxide glutathione peroxidase in human dermal fibroblasts abrogates UVA irradiation-induced expression of interstitial collagenase/ matrix metalloproteinase-1 by suppression of phosphatidylcholine hydroperoxide- mediated NFkappaB activation and interleukin-6 release
    • Wenk J, Schuller J, Hinrichs C et al. (2004) Overexpression of phospholipidhydroperoxide glutathione peroxidase in human dermal fibroblasts abrogates UVA irradiation-induced expression of interstitial collagenase/ matrix metalloproteinase-1 by suppression of phosphatidylcholine hydroperoxide- mediated NFkappaB activation and interleukin-6 release. J Biol Chem 279:45634-42
    • (2004) J Biol Chem , vol.279 , pp. 45634-45642
    • Wenk, J.1    Schuller, J.2    Hinrichs, C.3
  • 52
    • 33750720268 scopus 로고    scopus 로고
    • Protein oxidation and degradation during aging: Role in skin aging and neurodegeneration
    • Widmer R, Ziaja I, Grune T (2006) Protein oxidation and degradation during aging: role in skin aging and neurodegeneration. Free Radic Res 40:1259-68
    • (2006) Free Radic Res , vol.40 , pp. 1259-1268
    • Widmer, R.1    Ziaja, I.2    Grune, T.3
  • 53
    • 84858611035 scopus 로고    scopus 로고
    • Platelet-activating factor receptor agonists mediate xeroderma pigmentosum A photosensitivity
    • Yao Y, Harrison KA, Al-Hassani M et al. (2012) Platelet-activating factor receptor agonists mediate xeroderma pigmentosum A photosensitivity. J Biol Chem 287:9311-21
    • (2012) J Biol Chem , vol.287 , pp. 9311-9321
    • Yao, Y.1    Harrison, K.A.2    Al-Hassani, M.3


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