-
1
-
-
84895901860
-
Global cancer patterns: Causes and prevention
-
P. Vineis and C. P. Wild, "Global cancer patterns: causes and prevention, " The Lancet, vol. 383, no. 9916, pp. 549-557, 2014.
-
(2014)
The Lancet
, vol.383
, Issue.9916
, pp. 549-557
-
-
Vineis, P.1
Wild, C.P.2
-
2
-
-
84872264094
-
A review of global cancer burden: Trends, challenges, strategies, and a role for surgeons
-
C. Are, S. Rajaram, M. Are, et al., "A review of global cancer burden: trends, challenges, strategies, and a role for surgeons, " Journal of Surgical Oncology, vol. 107, no. 2, pp. 221-226, 2013.
-
(2013)
Journal of Surgical Oncology
, vol.107
, Issue.2
, pp. 221-226
-
-
Are, C.1
Rajaram, S.2
Are, M.3
-
3
-
-
0034614637
-
The hallmarks of cancer
-
D. Hanahan and R. A. Weinberg, "The hallmarks of cancer, " Cell, vol. 100, no. 1, pp. 57-70, 2000.
-
(2000)
Cell
, vol.100
, Issue.1
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
4
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
D. Hanahan and R. A. Weinberg, "Hallmarks of cancer: the next generation, " Cell, vol. 144, no. 5, pp. 646-674, 2011.
-
(2011)
Cell
, vol.144
, Issue.5
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
5
-
-
50249183899
-
Autophagy revisited: A conversation with Christian de Duve
-
D. J. Klionsky, "Autophagy revisited: a conversation with Christian de Duve, " Autophagy, vol. 4, no. 6, pp. 740-743, 2008.
-
(2008)
Autophagy
, vol.4
, Issue.6
, pp. 740-743
-
-
Klionsky, D.J.1
-
6
-
-
84890817481
-
Autophagy: From structure to metabolism to therapeutic regulation
-
M. A. Jardon, K. Rothe, S. Bortnik, et al., "Autophagy: from structure to metabolism to therapeutic regulation, " Autophagy, vol. 9, no. 12, pp. 2180-2182, 2013.
-
(2013)
Autophagy
, vol.9
, Issue.12
, pp. 2180-2182
-
-
Jardon, M.A.1
Rothe, K.2
Bortnik, S.3
-
7
-
-
71649087199
-
A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation
-
M. Hayashi-Nishino, N. Fujita, T. Noda, A. Yamaguchi, T. Yoshimori, and A. Yamamoto, "A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation, " Nature Cell Biology, vol. 11, no. 12, pp. 1433-1437, 2009.
-
(2009)
Nature Cell Biology
, vol.11
, Issue.12
, pp. 1433-1437
-
-
Hayashi-Nishino, M.1
Fujita, N.2
Noda, T.3
Yamaguchi, A.4
Yoshimori, T.5
Yamamoto, A.6
-
8
-
-
77953507889
-
Electron tomography reveals the endoplasmic reticulum as a membrane source for autophagosome formation
-
M. Hayashi-Nishino, N. Fujita, T. Noda, A. Yamaguchi, T. Yoshimori, and A. Yamamoto, "Electron tomography reveals the endoplasmic reticulum as a membrane source for autophagosome formation, " Autophagy, vol. 6, no. 2, pp. 301-303, 2010.
-
(2010)
Autophagy
, vol.6
, Issue.2
, pp. 301-303
-
-
Hayashi-Nishino, M.1
Fujita, N.2
Noda, T.3
Yamaguchi, A.4
Yoshimori, T.5
Yamamoto, A.6
-
9
-
-
84875365804
-
Autophagosomes form at ER-mitochondria contact sites
-
M. Hamasaki, N. Furuta, A. Matsuda, et al., "Autophagosomes form at ER-mitochondria contact sites, " Nature, vol. 495, no. 7441, pp. 389-393, 2013.
-
(2013)
Nature
, vol.495
, Issue.7441
, pp. 389-393
-
-
Hamasaki, M.1
Furuta, N.2
Matsuda, A.3
-
10
-
-
77956414236
-
The origin of the autophagosomal membrane
-
S. A. Tooze and T. Yoshimori, "The origin of the autophagosomal membrane, " Nature Cell Biology, vol. 12, no. 9, pp. 831-835, 2010.
-
(2010)
Nature Cell Biology
, vol.12
, Issue.9
, pp. 831-835
-
-
Tooze, S.A.1
Yoshimori, T.2
-
11
-
-
84892569830
-
An overview of autophagy: Morphology, mechanism, and regulation
-
K. R. Parzych and D. J. Klionsky, "An overview of autophagy: morphology, mechanism, and regulation, " Antioxidants and Redox Signaling, vol. 20, no. 3, pp. 460-473, 2014.
-
(2014)
Antioxidants and Redox Signaling
, vol.20
, Issue.3
, pp. 460-473
-
-
Parzych, K.R.1
Klionsky, D.J.2
-
12
-
-
84865592978
-
Amino acids and mTORC1: Fromlysosomes to disease
-
A. Efeyan, R. Zoncu, and D. M. Sabatini, "Amino acids and mTORC1: fromlysosomes to disease, " Trends inMolecularMedicine, vol. 18, no. 9, pp. 524-533, 2012.
-
(2012)
Trends InMolecularMedicine
, vol.18
, Issue.9
, pp. 524-533
-
-
Efeyan, A.1
Zoncu, R.2
Sabatini, D.M.3
-
13
-
-
78649338141
-
Autophagy and the integrated stress response
-
G. Kroemer, G. Marino, and B. Levine, "Autophagy and the integrated stress response, " Molecular Cell, vol. 40, no. 2, pp. 280-293, 2010.
-
(2010)
Molecular Cell
, vol.40
, Issue.2
, pp. 280-293
-
-
Kroemer, G.1
Marino, G.2
Levine, B.3
-
14
-
-
84889636479
-
Phosphoinositide 3-kinases as accelerators and brakes of autophagy
-
F. OFarrell, T. E. Rusten, and H. Stenmark, "Phosphoinositide 3-kinases as accelerators and brakes of autophagy, " FEBS Journal, vol. 280, no. 24, pp. 6322-6337, 2013.
-
(2013)
FEBS Journal
, vol.280
, Issue.24
, pp. 6322-6337
-
-
Ofarrell, F.1
Rusten, T.E.2
Stenmark, H.3
-
15
-
-
77953543377
-
The Beclin 1-VPS34 complex-at the crossroads of autophagy and beyond
-
S. F. Funderburk, Q. J. Wang, and Z. Yue, "The Beclin 1-VPS34 complex-at the crossroads of autophagy and beyond, " Trends in Cell Biology, vol. 20, no. 6, pp. 355-362, 2010.
-
(2010)
Trends in Cell Biology
, vol.20
, Issue.6
, pp. 355-362
-
-
Funderburk, S.F.1
Wang, Q.J.2
Yue, Z.3
-
16
-
-
64049113909
-
Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex
-
Y. Zhong, Q. J. Wang, X. Li, et al., "Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex, " Nature Cell Biology, vol. 11, no. 4, pp. 468-476, 2009.
-
(2009)
Nature Cell Biology
, vol.11
, Issue.4
, pp. 468-476
-
-
Zhong, Y.1
Wang, Q.J.2
Li, X.3
-
17
-
-
77953726483
-
Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation
-
H. E. J. Polson, J. De Lartigue, D. J. Rigden, et al., "Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation, " Autophagy, vol. 6, no. 4, pp. 506-522, 2010.
-
(2010)
Autophagy
, vol.6
, Issue.4
, pp. 506-522
-
-
Polson, H.E.J.1
De Lartigue, J.2
Rigden, D.J.3
-
18
-
-
80052145824
-
Freeze-fracture replica immunolabelling reveals human WIPI-1 and WIPI-2 as membrane proteins of autophagosomes
-
T. Proikas-Cezanne and H. Robenek, "Freeze-fracture replica immunolabelling reveals human WIPI-1 and WIPI-2 as membrane proteins of autophagosomes, " Journal of Cellular and Molecular Medicine, vol. 15, no. 9, pp. 2007-2010, 2011.
-
(2011)
Journal of Cellular and Molecular Medicine
, vol.15
, Issue.9
, pp. 2007-2010
-
-
Proikas-Cezanne, T.1
Robenek, H.2
-
19
-
-
84898757170
-
Dynamic regulation of macroautophagy by distinctive ubiquitin-like proteins
-
D. J. Klionsky and B. A. Schulman, "Dynamic regulation of macroautophagy by distinctive ubiquitin-like proteins, " Nature Structural and Molecular Biology, vol. 21, no. 4, pp. 336-345, 2014.
-
(2014)
Nature Structural and Molecular Biology
, vol.21
, Issue.4
, pp. 336-345
-
-
Klionsky, D.J.1
Schulman, B.A.2
-
20
-
-
84892154950
-
Two ubiquitin-like conjugation systems that mediatemembrane formation during autophagy
-
H. Nakatogawa, "Two ubiquitin-like conjugation systems that mediatemembrane formation during autophagy, " Essays in Biochemistry, vol. 55, no. 1, pp. 39-50, 2013.
-
(2013)
Essays in Biochemistry
, vol.55
, Issue.1
, pp. 39-50
-
-
Nakatogawa, H.1
-
21
-
-
84934441413
-
Methods for assessing autophagy and autophagic cell death
-
E. Tasdemir, L. Galluzzi, M. C. Maiuri, et al., "Methods for assessing autophagy and autophagic cell death, " Methods in Molecular Biology, vol. 445, pp. 29-76, 2008.
-
(2008)
Methods in Molecular Biology
, vol.445
, pp. 29-76
-
-
Tasdemir, E.1
Galluzzi, L.2
Maiuri, M.C.3
-
22
-
-
0036735949
-
Role of LAMP-2 in lysosome biogenesis and autophagy
-
E.-L. Eskelinen, A. L. Illert, Y. Tanaka, et al., "Role of LAMP-2 in lysosome biogenesis and autophagy, " Molecular Biology of the Cell, vol. 13, no. 9, pp. 3355-3368, 2002.
-
(2002)
Molecular Biology of the Cell
, vol.13
, Issue.9
, pp. 3355-3368
-
-
Eskelinen, E.-L.1
Illert, A.L.2
Tanaka, Y.3
-
23
-
-
84893823338
-
Regulation of autophagy by the Rab GTPase network
-
X. Ao, L. Zou, and Y. Wu, "Regulation of autophagy by the Rab GTPase network, " Cell Death and Differentiation, vol. 21, no. 3, pp. 348-358, 2014.
-
(2014)
Cell Death and Differentiation
, vol.21
, Issue.3
, pp. 348-358
-
-
Ao, X.1
Zou, L.2
Wu, Y.3
-
24
-
-
0036253107
-
SKD1 AAA ATPase-dependent endosomal transport is involved in autolysosome formation
-
A. Nara, N. Mizushima, A. Yamamoto, Y. Kabeya, Y. Ohsumi, and T. Yoshimori, "SKD1 AAA ATPase-dependent endosomal transport is involved in autolysosome formation, " Cell Structure and Function, vol. 27, no. 1, pp. 29-37, 2002.
-
(2002)
Cell Structure and Function
, vol.27
, Issue.1
, pp. 29-37
-
-
Nara, A.1
Mizushima, N.2
Yamamoto, A.3
Kabeya, Y.4
Ohsumi, Y.5
Yoshimori, T.6
-
25
-
-
77955708390
-
Overview of macroautophagy regulation in mammalian cells
-
M. Mehrpour, A. Esclatine, I. Beau, and P. Codogno, "Overview of macroautophagy regulation in mammalian cells, " Cell Research, vol. 20, no. 7, pp. 748-762, 2010.
-
(2010)
Cell Research
, vol.20
, Issue.7
, pp. 748-762
-
-
Mehrpour, M.1
Esclatine, A.2
Beau, I.3
Codogno, P.4
-
26
-
-
78650510609
-
MTOR: From growth signal integration to cancer, diabetes and ageing
-
R. Zoncu, A. Efeyan, and D. M. Sabatini, "MTOR: from growth signal integration to cancer, diabetes and ageing, " Nature Reviews Molecular Cell Biology, vol. 12, no. 1, pp. 21-35, 2011.
-
(2011)
Nature Reviews Molecular Cell Biology
, vol.12
, Issue.1
, pp. 21-35
-
-
Zoncu, R.1
Efeyan, A.2
Sabatini, D.M.3
-
27
-
-
79958696694
-
The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling
-
P. P. Hsu, S. A. Kang, J. Rameseder, et al., "The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling, " Science, vol. 332, no. 6035, pp. 1317-1322, 2011.
-
(2011)
Science
, vol.332
, Issue.6035
, pp. 1317-1322
-
-
Hsu, P.P.1
Kang, S.A.2
Rameseder, J.3
-
28
-
-
84873665112
-
Regulation of mTORC1 by the Rag GTPases is necessary for neonatal autophagy and survival
-
A. Efeyan, R. Zoncu, S. Chang, et al., "Regulation of mTORC1 by the Rag GTPases is necessary for neonatal autophagy and survival, " Nature, vol. 493, no. 7434, pp. 679-683, 2013.
-
(2013)
Nature
, vol.493
, Issue.7434
, pp. 679-683
-
-
Efeyan, A.1
Zoncu, R.2
Chang, S.3
-
29
-
-
70350449062
-
MTORC1 phosphorylates the ULK1-mAtg13-FIP200 autophagy regulatory complex
-
article pe51
-
E. Y. Chan, "MTORC1 phosphorylates the ULK1-mAtg13-FIP200 autophagy regulatory complex, " Science Signaling, vol. 2, no. 84, article pe51, 2009.
-
(2009)
Science Signaling
, vol.2
, Issue.84
-
-
Chan, E.Y.1
-
30
-
-
65249119430
-
Nutrient-dependent mTORCl association with the ULK1-Atg13-FIP200 complex required for autophagy
-
N. Hosokawa, T. Hara, T. Kaizuka, et al., "Nutrient-dependent mTORCl association with the ULK1-Atg13-FIP200 complex required for autophagy, " Molecular Biology of the Cell, vol. 20, no. 7, pp. 1981-1991, 2009.
-
(2009)
Molecular Biology of the Cell
, vol.20
, Issue.7
, pp. 1981-1991
-
-
Hosokawa, N.1
Hara, T.2
Kaizuka, T.3
-
31
-
-
79953211917
-
Nutrient starvation elicits an acute autophagic response mediated by Ulk1 dephosphorylation and its subsequent dissociation from AMPK
-
L. Shang, S. Chen, F. Du, S. Li, L. Zhao, and X. Wang, "Nutrient starvation elicits an acute autophagic response mediated by Ulk1 dephosphorylation and its subsequent dissociation from AMPK, " Proceedings of the National Academy of Sciences of the United States of America, vol. 108, no. 12, pp. 4788-4793, 2011.
-
(2011)
Proceedings of the National Academy of Sciences of the United States of America
, vol.108
, Issue.12
, pp. 4788-4793
-
-
Shang, L.1
Chen, S.2
Du, F.3
Li, S.4
Zhao, L.5
Wang, X.6
-
32
-
-
79551598347
-
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
-
J. Kim, M. Kundu, B. Viollet, and K.-L. Guan, "AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1, " Nature Cell Biology, vol. 13, no. 2, pp. 132-141, 2011.
-
(2011)
Nature Cell Biology
, vol.13
, Issue.2
, pp. 132-141
-
-
Kim, J.1
Kundu, M.2
Viollet, B.3
Guan, K.-L.4
-
33
-
-
78149476877
-
The association of AMPK with ULK1 regulates autophagy
-
Article ID e15394
-
J. W. Lee, S. Park, Y. Takahashi, and H.-G. Wang, "The association of AMPK with ULK1 regulates autophagy, " PLoS ONE, vol. 5, no. 11, Article ID e15394, 2010.
-
(2010)
PLoS ONE
, vol.5
, Issue.11
-
-
Lee, J.W.1
Park, S.2
Takahashi, Y.3
Wang, H.-G.4
-
34
-
-
84881413580
-
Reactive nitrogen species regulate autophagy through ATM-AMPKTSC2-mediated suppression of mTORC1
-
D. N. Tripathi, R. Chowdhury, L. J. Trudel, et al., "Reactive nitrogen species regulate autophagy through ATM-AMPKTSC2-mediated suppression of mTORC1, " Proceedings of the National Academy of Sciences of the United States of America, vol. 110, no. 32, pp. E2950-E2957, 2013.
-
(2013)
Proceedings of the National Academy of Sciences of the United States of America
, vol.110
, Issue.32
, pp. E2950-E2957
-
-
Tripathi, D.N.1
Chowdhury, R.2
Trudel, L.J.3
-
35
-
-
84884634690
-
Regulation of autophagy by mTOR-dependent and mTOR-independent pathways: Autophagy dysfunction in neurodegenerative diseases and therapeutic application of autophagy enhancers
-
S. Sarkar, "Regulation of autophagy by mTOR-dependent and mTOR-independent pathways: autophagy dysfunction in neurodegenerative diseases and therapeutic application of autophagy enhancers, " Biochemical Society Transactions, vol. 41, no. 5, pp. 1103-1130, 2013.
-
(2013)
Biochemical Society Transactions
, vol.41
, Issue.5
, pp. 1103-1130
-
-
Sarkar, S.1
-
36
-
-
33644513730
-
Beyond PTEN mutations: The PI3K pathway as an integrator of multiple inputs during tumorigenesis
-
M. Cully, H. You, A. J. Levine, and T. W. Mak, "Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis, " Nature Reviews Cancer, vol. 6, no. 3, pp. 184-192, 2006.
-
(2006)
Nature Reviews Cancer
, vol.6
, Issue.3
, pp. 184-192
-
-
Cully, M.1
You, H.2
Levine, A.J.3
Mak, T.W.4
-
37
-
-
48249092267
-
Bcl-2 family members: Dual regulators of apoptosis and autophagy
-
B. Levine, S. Sinha, and G. Kroemer, "Bcl-2 family members: dual regulators of apoptosis and autophagy, " Autophagy, vol. 4, no. 5, pp. 600-606, 2008.
-
(2008)
Autophagy
, vol.4
, Issue.5
, pp. 600-606
-
-
Levine, B.1
Sinha, S.2
Kroemer, G.3
-
38
-
-
33745307617
-
Ras, PI(3)K and mTOR signalling controls tumour cell growth
-
R. J. Shaw and L. C. Cantley, "Ras, PI(3)K and mTOR signalling controls tumour cell growth, " Nature, vol. 441, no. 7092, pp. 424-430, 2006.
-
(2006)
Nature
, vol.441
, Issue.7092
, pp. 424-430
-
-
Shaw, R.J.1
Cantley, L.C.2
-
39
-
-
34547132328
-
Tissue-specific autophagy alterations and increased tumorigenesis in mice deficient in Atg4C/autophagin-3
-
G. Marino, N. Salvador-Montoliu, A. Fueyo, E. Knecht, N. Mizushima, and C. Lopez-Otin, "Tissue-specific autophagy alterations and increased tumorigenesis in mice deficient in Atg4C/autophagin-3, " Journal of Biological Chemistry, vol. 282, no. 25, pp. 18573-18583, 2007.
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.25
, pp. 18573-18583
-
-
Marino, G.1
Salvador-Montoliu, N.2
Fueyo, A.3
Knecht, E.4
Mizushima, N.5
Lopez-Otin, C.6
-
40
-
-
57449121645
-
The tumor suppressor gene ARHI regulates autophagy and tumor dormancy in human ovarian cancer cells
-
Z. Lu, R. Z. Luo, Y. Lu, et al., "The tumor suppressor gene ARHI regulates autophagy and tumor dormancy in human ovarian cancer cells, " The Journal of Clinical Investigation, vol. 118, no. 12, pp. 3917-3929, 2008.
-
(2008)
The Journal of Clinical Investigation
, vol.118
, Issue.12
, pp. 3917-3929
-
-
Lu, Z.1
Luo, R.Z.2
Lu, Y.3
-
41
-
-
0000906170
-
Induction of autophagy and inhibition of tumorigenesis by beclin 1
-
X. H. Liang, S. Jackson, M. Seaman, et al., "Induction of autophagy and inhibition of tumorigenesis by beclin 1, " Nature, vol. 402, no. 6762, pp. 672-676, 1999.
-
(1999)
Nature
, vol.402
, Issue.6762
, pp. 672-676
-
-
Liang, X.H.1
Jackson, S.2
Seaman, M.3
-
42
-
-
33745962416
-
BH3-only proteins in cell death initiation, malignant disease and anticancer therapy
-
V. Labi, M. Erlacher, S. Kiessling, and A. Villunger, "BH3-only proteins in cell death initiation, malignant disease and anticancer therapy, " Cell Death and Differentiation, vol. 13, no. 8, pp. 1325-1338, 2006.
-
(2006)
Cell Death and Differentiation
, vol.13
, Issue.8
, pp. 1325-1338
-
-
Labi, V.1
Erlacher, M.2
Kiessling, S.3
Villunger, A.4
-
43
-
-
68249106060
-
BH3-only proteins in apoptosis and beyond: An overview
-
E. Lomonosova and G. Chinnadurai, "BH3-only proteins in apoptosis and beyond: an overview, " Oncogene, vol. 27, no. 1, pp. S2-S19, 2008.
-
(2008)
Oncogene
, vol.27
, Issue.1
, pp. S2-S19
-
-
Lomonosova, E.1
Chinnadurai, G.2
-
44
-
-
34250894388
-
BH3-only proteins and BH3 mimetics induce autophagy by competitively disrupting the interaction between Beclin 1 and Bcl-2/Bcl-XL
-
M. C. Maiuri, A. Criollo, E. Tasdemir, et al., "BH3-only proteins and BH3 mimetics induce autophagy by competitively disrupting the interaction between Beclin 1 and Bcl-2/Bcl-XL, " Autophagy, vol. 3, no. 4, pp. 374-376, 2007.
-
(2007)
Autophagy
, vol.3
, Issue.4
, pp. 374-376
-
-
Maiuri, M.C.1
Criollo, A.2
Tasdemir, E.3
-
45
-
-
34848899280
-
Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis
-
Y. Takahashi, D. Coppola, N. Matsushita, et al., "Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis, " Nature Cell Biology, vol. 9, no. 10, pp. 1142-1151, 2007.
-
(2007)
Nature Cell Biology
, vol.9
, Issue.10
, pp. 1142-1151
-
-
Takahashi, Y.1
Coppola, D.2
Matsushita, N.3
-
46
-
-
43949145220
-
DAPK-1 binding to a linear peptide motif in MAP1B stimulates autophagy and membrane blebbing
-
B. Harrison, M. Kraus, L. Burch, et al., "DAPK-1 binding to a linear peptide motif in MAP1B stimulates autophagy and membrane blebbing, " The Journal of Biological Chemistry, vol. 283, no. 15, pp. 9999-10014, 2008.
-
(2008)
The Journal of Biological Chemistry
, vol.283
, Issue.15
, pp. 9999-10014
-
-
Harrison, B.1
Kraus, M.2
Burch, L.3
-
47
-
-
33947250696
-
The energy sensing LKB1-AMPK pathway regulates p27kip1 phosphorylation mediating the decision to enter autophagy or apoptosis
-
J. Liang, S. H. Shao, Z.-X. Xu, et al., "The energy sensing LKB1-AMPK pathway regulates p27kip1 phosphorylation mediating the decision to enter autophagy or apoptosis, " Nature Cell Biology, vol. 9, no. 2, pp. 218-224, 2007.
-
(2007)
Nature Cell Biology
, vol.9
, Issue.2
, pp. 218-224
-
-
Liang, J.1
Shao, S.H.2
Xu, Z.-X.3
-
48
-
-
34547926839
-
LKB1 modulates lung cancer differentiation and metastasis
-
H. Ji, M. R. Ramsey, D. N. Hayes, et al., "LKB1 modulates lung cancer differentiation and metastasis, " Nature, vol. 448, no. 7155, pp. 807-810, 2007.
-
(2007)
Nature
, vol.448
, Issue.7155
, pp. 807-810
-
-
Ji, H.1
Ramsey, M.R.2
Hayes, D.N.3
-
49
-
-
0141920730
-
Rab7 prevents growth factor-independent survival by inhibiting cellautonomous nutrient transporter expression
-
A. L. Edinger, R. M. Cinalli, and C. B. Thompson, "Rab7 prevents growth factor-independent survival by inhibiting cellautonomous nutrient transporter expression, " Developmental Cell, vol. 5, no. 4, pp. 571-582, 2003.
-
(2003)
Developmental Cell
, vol.5
, Issue.4
, pp. 571-582
-
-
Edinger, A.L.1
Cinalli, R.M.2
Thompson, C.B.3
-
50
-
-
34447272449
-
Tuberous sclerosis complex: Advances in diagnosis, genetics, and management
-
R. A. Schwartz, G. Fernandez, K. Kotulska, and S. Jozwiak, "Tuberous sclerosis complex: advances in diagnosis, genetics, and management, " Journal of the American Academy of Dermatology, vol. 57, no. 2, pp. 189-202, 2007.
-
(2007)
Journal of the American Academy of Dermatology
, vol.57
, Issue.2
, pp. 189-202
-
-
Schwartz, R.A.1
Fernandez, G.2
Kotulska, K.3
Jozwiak, S.4
-
51
-
-
84873660610
-
Mechanisms of disease: Autophagy in human health and disease
-
A. M. K. Choi, S. W. Ryter, and B. Levine, "Mechanisms of disease: autophagy in human health and disease, "TheNew England Journal of Medicine, vol. 368, no. 7, pp. 651-662, 2013.
-
(2013)
TheNew England Journal of Medicine
, vol.368
, Issue.7
, pp. 651-662
-
-
Choi, A.M.K.1
Ryter, S.W.2
Levine, B.3
-
52
-
-
0344142468
-
Cloning and genomic organization of beclin 1, a cand idate tumor suppressor gene on chromosome 17q21
-
V. M. Aita, X. H. Liang, V. V. V. S. Murty, et al., "Cloning and genomic organization of beclin 1, a cand idate tumor suppressor gene on chromosome 17q21, " Genomics, vol. 59, no. 1, pp. 5965, 1999.
-
(1999)
Genomics
, vol.59
, Issue.1
, pp. 59-65
-
-
Aita, V.M.1
Liang, X.H.2
Murty, V.V.V.S.3
-
53
-
-
9144240441
-
Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene
-
X. Qu, J. Yu, G. Bhagat, et al., "Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene, " Journal of Clinical Investigation, vol. 112, no. 12, pp. 1809-1820, 2003.
-
(2003)
Journal of Clinical Investigation
, vol.112
, Issue.12
, pp. 1809-1820
-
-
Qu, X.1
Yu, J.2
Bhagat, G.3
-
54
-
-
0345166111
-
Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
-
Z. Yue, S. Jin, C. Yang, A. J. Levine, and N. Heintz, "Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor, " Proceedings of the National Academy of Sciences of the United States of America, vol. 100, no. 25, pp. 15077-15082, 2003.
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.25
, pp. 15077-15082
-
-
Yue, Z.1
Jin, S.2
Yang, C.3
Levine, A.J.4
Heintz, N.5
-
55
-
-
84894972613
-
Evaluating DAPK as a therapeutic target
-
Y. Huang, L. Chen, L. Guo, T. R. Hupp, and Y. Lin, "Evaluating DAPK as a therapeutic target, " Apoptosis, vol. 19, no. 2, pp. 371-386, 2014.
-
(2014)
Apoptosis
, vol.19
, Issue.2
, pp. 371-386
-
-
Huang, Y.1
Chen, L.2
Guo, L.3
Hupp, T.R.4
Lin, Y.5
-
56
-
-
84899943041
-
Cancer therapeutics: Targeting the apoptotic pathway
-
K. H. Khan, M. Blanco-Codesido, and L. R. Molife, "Cancer therapeutics: targeting the apoptotic pathway, " Critical Reviews in Oncology/Hematology, vol. 90, no. 3, pp. 200-219, 2014.
-
(2014)
Critical Reviews in Oncology/Hematology
, vol.90
, Issue.3
, pp. 200-219
-
-
Khan, K.H.1
Blanco-Codesido, M.2
Molife, L.R.3
-
57
-
-
84870206960
-
Mitochondria: Master regulators of danger signalling
-
L. Galluzzi, O. Kepp, and G. Kroemer, "Mitochondria: master regulators of danger signalling, " Nature Reviews Molecular Cell Biology, vol. 13, no. 12, pp. 780-788, 2012.
-
(2012)
Nature Reviews Molecular Cell Biology
, vol.13
, Issue.12
, pp. 780-788
-
-
Galluzzi, L.1
Kepp, O.2
Kroemer, G.3
-
58
-
-
25144457455
-
Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
-
S. Pattingre, A. Tassa, X. Qu, et al., "Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy, " Cell, vol. 122, no. 6, pp. 927-939, 2005.
-
(2005)
Cell
, vol.122
, Issue.6
, pp. 927-939
-
-
Pattingre, S.1
Tassa, A.2
Qu, X.3
-
59
-
-
34248998801
-
Functional and physical interaction between Bcl-XL and a BH3-like domain in Beclin-1
-
M. C. Maiuri, G. le Toumelin, A. Criollo, et al., "Functional and physical interaction between Bcl-XL and a BH3-like domain in Beclin-1, " EMBO Journal, vol. 26, no. 10, pp. 2527-2539, 2007.
-
(2007)
EMBO Journal
, vol.26
, Issue.10
, pp. 2527-2539
-
-
Maiuri, M.C.1
Le Toumelin, G.2
Criollo, A.3
-
60
-
-
69349087479
-
Anti-and pro-tumor functions of autophagy
-
E. Morselli, L. Galluzzi, O. Kepp, et al., "Anti-and pro-tumor functions of autophagy, " Biochimicaet Biophysica Acta:Molecular Cell Research, vol. 1793, no. 9, pp. 1524-1532, 2009.
-
(2009)
Biochimicaet Biophysica Acta: Molecular Cell Research
, vol.1793
, Issue.9
, pp. 1524-1532
-
-
Morselli, E.1
Galluzzi, L.2
Kepp, O.3
-
61
-
-
34047271129
-
Protein and mRNA expression of autophagy gene Beclin 1 in human brain tumours
-
C. Miracco, E. Cosci, G. Oliveri, et al., "Protein and mRNA expression of autophagy gene Beclin 1 in human brain tumours, " International Journal of Oncology, vol. 30, no. 2, pp. 429-436, 2007.
-
(2007)
International Journal of Oncology
, vol.30
, Issue.2
, pp. 429-436
-
-
Miracco, C.1
Cosci, E.2
Oliveri, G.3
-
62
-
-
34347404887
-
Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis
-
V. Karantza-Wadsworth, S. Patel, O. Kravchuk, et al., "Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis, " Genes & Development, vol. 21, no. 13, pp. 1621-1635, 2007.
-
(2007)
Genes & Development
, vol.21
, Issue.13
, pp. 1621-1635
-
-
Karantza-Wadsworth, V.1
Patel, S.2
Kravchuk, O.3
-
63
-
-
84884262668
-
EGFR-mediated beclin 1 phosphorylation in autophagy suppression, tumor progression, and tumor chemoresistance
-
Y. Wei, Z. Zou, N. Becker, et al., "EGFR-mediated beclin 1 phosphorylation in autophagy suppression, tumor progression, and tumor chemoresistance, " Cell, vol. 154, no. 6, pp. 1269-1284, 2013.
-
(2013)
Cell
, vol.154
, Issue.6
, pp. 1269-1284
-
-
Wei, Y.1
Zou, Z.2
Becker, N.3
-
64
-
-
34347344990
-
Ambra1 regulates autophagy and development of the nervous system
-
G. Maria Fimia, A. Stoykova, A. Romagnoli, et al., "Ambra1 regulates autophagy and development of the nervous system, " Nature, vol. 447, no. 7148, pp. 1121-1125, 2007.
-
(2007)
Nature
, vol.447
, Issue.7148
, pp. 1121-1125
-
-
Maria Fimia, G.1
Stoykova, A.2
Romagnoli, A.3
-
65
-
-
33745751085
-
Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG
-
C. Liang, P. Feng, B. Ku, et al., "Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG, " Nature Cell Biology, vol. 8, no. 7, pp. 688-698, 2006.
-
(2006)
Nature Cell Biology
, vol.8
, Issue.7
, pp. 688-698
-
-
Liang, C.1
Feng, P.2
Ku, B.3
-
66
-
-
84861526009
-
Deconvoluting the context-dependent role for autophagy in cancer
-
E. White, "Deconvoluting the context-dependent role for autophagy in cancer, " Nature Reviews Cancer, vol. 12, no. 6, pp. 401-410, 2012.
-
(2012)
Nature Reviews Cancer
, vol.12
, Issue.6
, pp. 401-410
-
-
White, E.1
-
67
-
-
80053501671
-
Beclin1 controls the levels of p53 by regulating the deubiquitination activity of USP10 and USP13
-
J. Liu, H. Xia, M. Kimet al., "Beclin1 controls the levels of p53 by regulating the deubiquitination activity of USP10 and USP13, " Cell, vol. 147, no. 1, pp. 223-234, 2011.
-
(2011)
Cell
, vol.147
, Issue.1
, pp. 223-234
-
-
Liu, J.1
Xia, H.2
Kim, M.3
-
68
-
-
11144245626
-
The role of autophagy during the early neonatal starvation period
-
A. Kuma, M. Hatano, M. Matsui, et al., "The role of autophagy during the early neonatal starvation period, " Nature, vol. 432, no. 7020, pp. 1032-1036, 2004.
-
(2004)
Nature
, vol.432
, Issue.7020
, pp. 1032-1036
-
-
Kuma, A.1
Hatano, M.2
Matsui, M.3
-
69
-
-
21044455137
-
Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice
-
M. Komatsu, S. Waguri, T. Ueno, et al., "Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice, " Journal of Cell Biology, vol. 169, no. 3, pp. 425-434, 2005.
-
(2005)
Journal of Cell Biology
, vol.169
, Issue.3
, pp. 425-434
-
-
Komatsu, M.1
Waguri, S.2
Ueno, T.3
-
70
-
-
56249090667
-
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production
-
T. Saitoh, N. Fujita, M. H. Jang, et al., "Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production, " Nature, vol. 456, no. 7219, pp. 264-268, 2008.
-
(2008)
Nature
, vol.456
, Issue.7219
, pp. 264-268
-
-
Saitoh, T.1
Fujita, N.2
Jang, M.H.3
-
71
-
-
79952118280
-
Regulationof inflammation by autophagy
-
T. Saitoh, F. Naonobu, T. Yoshimori, and S. Akira, "Regulationof inflammation by autophagy, " Tanpakushitsu kakusan koso, vol. 54, supplement 8, pp. 1119-1124, 2009.
-
(2009)
Tanpakushitsu Kakusan Koso
, vol.54
, pp. 1119-1124
-
-
Saitoh, T.1
Naonobu, F.2
Yoshimori, T.3
Akira, S.4
-
72
-
-
57549094368
-
The Atg8 conjugation system is indispensable for proper development of autophagic isolationmembranes in mice
-
Y.-S. Sou, S. Waguri, J.-I. Iwata, et al., "The Atg8 conjugation system is indispensable for proper development of autophagic isolationmembranes in mice, "Molecular Biology of the Cell, vol. 19, no. 11, pp. 4762-4775, 2008.
-
(2008)
Molecular Biology of the Cell
, vol.19
, Issue.11
, pp. 4762-4775
-
-
Sou, Y.-S.1
Waguri, S.2
Iwata, J.-I.3
-
73
-
-
79955377420
-
Autophagy-deficient mice develop multiple liver tumors
-
A. Takamura, M. Komatsu, T. Hara, et al., "Autophagy-deficient mice develop multiple liver tumors, " Genes and Development, vol. 25, no. 8, pp. 795-800, 2011.
-
(2011)
Genes and Development
, vol.25
, Issue.8
, pp. 795-800
-
-
Takamura, A.1
Komatsu, M.2
Hara, T.3
-
74
-
-
84885350394
-
Autophagy sustains mitochondrial glutamine metabolism and growth of BrafV600E-driven lung tumors
-
A. M. Strohecker, J. Y. Guo, G. Karsli-Uzunbas, et al., "Autophagy sustains mitochondrial glutamine metabolism and growth of BrafV600E-driven lung tumors, " Cancer Discovery, vol. 3, no. 11, pp. 1272-1285, 2013.
-
(2013)
Cancer Discovery
, vol.3
, Issue.11
, pp. 1272-1285
-
-
Strohecker, A.M.1
Guo, J.Y.2
Karsli-Uzunbas, G.3
-
75
-
-
0031448836
-
NotI linking/jumping clones of human chromosome 3: Mapping of the TFRC, RAB7 and HAUSP genes to regions rearranged in leukemia and deleted in solid tumors
-
V. I. Kashuba, R. Z. Gizatullin, A. I. Protopopov, et al., "NotI linking/ jumping clones of human chromosome 3: mapping of the TFRC, RAB7 and HAUSP genes to regions rearranged in leukemia and deleted in solid tumors, " FEBS Letters, vol. 419, no. 2-3, pp. 181185, 1997.
-
(1997)
FEBS Letters
, vol.419
, Issue.2-3
, pp. 181-185
-
-
Kashuba, V.I.1
Gizatullin, R.Z.2
Protopopov, A.I.3
-
76
-
-
84902177842
-
Mutational land scape of the essential autophagy gene BECN1 in human cancers
-
S. V. Laddha, S. Ganesan, C. S. Chan, and E. White, "Mutational land scape of the essential autophagy gene BECN1 in human cancers, "Molecular Cancer Research, vol. 12, no. 4, pp. 485-490, 2014.
-
(2014)
Molecular Cancer Research
, vol.12
, Issue.4
, pp. 485-490
-
-
Laddha, S.V.1
Ganesan, S.2
Chan, C.S.3
White, E.4
-
77
-
-
0034011261
-
Oxyradicals and DNA damage
-
L. J. Marnett, "Oxyradicals and DNA damage, " Carcinogenesis, vol. 21, no. 3, pp. 361-370, 2000.
-
(2000)
Carcinogenesis
, vol.21
, Issue.3
, pp. 361-370
-
-
Marnett, L.J.1
-
78
-
-
44449105437
-
Reactive species: A cell damaging rout assisting to chemical carcinogens
-
M. E. Goetz and A. Luch, "Reactive species: a cell damaging rout assisting to chemical carcinogens, " Cancer Letters, vol. 266, no. 1, pp. 73-83, 2008.
-
(2008)
Cancer Letters
, vol.266
, Issue.1
, pp. 73-83
-
-
Goetz, M.E.1
Luch, A.2
-
79
-
-
77649338652
-
Mitochondrial gateways to cancer
-
L. Galluzzi, E. Morselli, O. Kepp, et al., "Mitochondrial gateways to cancer, "Molecular Aspects of Medicine, vol. 31, no. 1, pp. 1-20, 2010.
-
(2010)
Molecular Aspects of Medicine
, vol.31
, Issue.1
, pp. 1-20
-
-
Galluzzi, L.1
Morselli, E.2
Kepp, O.3
-
80
-
-
34249863298
-
Autophagy suppresses tumor progression by limiting chromosomal instability
-
R. Mathew, S. Kongara, B. Beaudoin, et al., "Autophagy suppresses tumor progression by limiting chromosomal instability, " Genes and Development, vol. 21, no. 11, pp. 1367-1381, 2007.
-
(2007)
Genes and Development
, vol.21
, Issue.11
, pp. 1367-1381
-
-
Mathew, R.1
Kongara, S.2
Beaudoin, B.3
-
81
-
-
66449099090
-
Autophagy suppresses tumorigenesis through elimination of p62
-
R. Mathew, C. M. Karp, B. Beaudoin, et al., "Autophagy suppresses tumorigenesis through elimination of p62, " Cell, vol. 137, no. 6, pp. 1062-1075, 2009.
-
(2009)
Cell
, vol.137
, Issue.6
, pp. 1062-1075
-
-
Mathew, R.1
Karp, C.M.2
Beaudoin, B.3
-
82
-
-
79956159030
-
Oncosuppressive functions of autophagy
-
E. Morselli, L. Galluzzi, O. Kepp, et al., "Oncosuppressive functions of autophagy, " Antioxidants and Redox Signaling, vol. 14, no. 11, pp. 2251-2269, 2011.
-
(2011)
Antioxidants and Redox Signaling
, vol.14
, Issue.11
, pp. 2251-2269
-
-
Morselli, E.1
Galluzzi, L.2
Kepp, O.3
-
83
-
-
79952228407
-
Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis
-
J. Y. Guo, H.-Y. Chen, R. Mathew, et al., "Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis, " Genes and Development, vol. 25, no. 5, pp. 460-470, 2011.
-
(2011)
Genes and Development
, vol.25
, Issue.5
, pp. 460-470
-
-
Guo, J.Y.1
Chen, H.-Y.2
Mathew, R.3
-
84
-
-
84879777723
-
Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis
-
J. Y. Guo, G. Karsli-Uzunbas, R. Mathew, et al., "Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis, " Genes and Development, vol. 27, no. 13, pp. 1447-1461, 2013.
-
(2013)
Genes and Development
, vol.27
, Issue.13
, pp. 1447-1461
-
-
Guo, J.Y.1
Karsli-Uzunbas, G.2
Mathew, R.3
-
85
-
-
79952229430
-
Pancreatic cancers require autophagy for tumor growth
-
S. H. Yang, X. Wang, G. Contino, et al., "Pancreatic cancers require autophagy for tumor growth, " Genes and Development, vol. 25, no. 7, pp. 717-729, 2011.
-
(2011)
Genes and Development
, vol.25
, Issue.7
, pp. 717-729
-
-
Yang, S.H.1
Wang, X.2
Contino, G.3
-
86
-
-
75949130828
-
PINK1/Parkinmediated mitophagy is dependent on VDAC1 and p62/SQSTM1
-
S. Geisler, K. M. Holmstrom, D. Skujat, et al., "PINK1/Parkinmediated mitophagy is dependent on VDAC1 and p62/SQSTM1, " Nature Cell Biology, vol. 12, no. 2, pp. 119-131, 2010.
-
(2010)
Nature Cell Biology
, vol.12
, Issue.2
, pp. 119-131
-
-
Geisler, S.1
Holmstrom, K.M.2
Skujat, D.3
-
87
-
-
66449114033
-
P62 at the crossroads of autophagy, apoptosis, and cancer
-
J. Moscat and M. T. Diaz-Meco, "p62 at the crossroads of autophagy, apoptosis, and cancer, " Cell, vol. 137, no. 6, pp. 1001-1004, 2009.
-
(2009)
Cell
, vol.137
, Issue.6
, pp. 1001-1004
-
-
Moscat, J.1
Diaz-Meco, M.T.2
-
88
-
-
79955492012
-
Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells
-
Y. Inami, S. Waguri, A. Sakamoto, et al., "Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells, " Journal of Cell Biology, vol. 193, no. 2, pp. 275-284, 2011.
-
(2011)
Journal of Cell Biology
, vol.193
, Issue.2
, pp. 275-284
-
-
Inami, Y.1
Waguri, S.2
Sakamoto, A.3
-
89
-
-
77649265091
-
The selective autophagy substrate p62 activates the stress responsive transcription factorNrf2 through inactivation of Keap1
-
M. Komatsu, H. Kurokawa, S. Waguri, et al., "The selective autophagy substrate p62 activates the stress responsive transcription factorNrf2 through inactivation of Keap1, " Nature Cell Biology, vol. 12, no. 3, pp. 213-223, 2010.
-
(2010)
Nature Cell Biology
, vol.12
, Issue.3
, pp. 213-223
-
-
Komatsu, M.1
Kurokawa, H.2
Waguri, S.3
-
90
-
-
77953366801
-
A noncanonical mechanism of Nrf2 activation by autophagy deficiency: Direct interaction between keap1 and p62
-
A. Lau, X.-J. Wang, F. Zhao, et al., "A noncanonical mechanism of Nrf2 activation by autophagy deficiency: direct interaction between keap1 and p62, "Molecular and Cellular Biology, vol. 30, no. 13, pp. 3275-3285, 2010.
-
(2010)
Molecular and Cellular Biology
, vol.30
, Issue.13
, pp. 3275-3285
-
-
Lau, A.1
Wang, X.-J.2
Zhao, F.3
-
91
-
-
84872598312
-
Cancer-related inflammation
-
J. Cand ido and T. Hagemann, "Cancer-related inflammation, " Journal of Clinical Immunology, vol. 33, supplement 1, pp. S79-S84, 2013.
-
(2013)
Journal of Clinical Immunology
, vol.33
, pp. S79-S84
-
-
Candido, J.1
Hagemann, T.2
-
92
-
-
33745713171
-
Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis
-
K. Degenhardt, R. Mathew, B. Beaudoin, et al., "Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis, " Cancer Cell, vol. 10, no. 1, pp. 51-64, 2006.
-
(2006)
Cancer Cell
, vol.10
, Issue.1
, pp. 51-64
-
-
Degenhardt, K.1
Mathew, R.2
Beaudoin, B.3
-
93
-
-
69949106925
-
The double-edged sword of autophagy modulation in cancer
-
E. White and R. S. DiPaola, "The double-edged sword of autophagy modulation in cancer, " Clinical Cancer Research, vol. 15, no. 17, pp. 5308-5316, 2009.
-
(2009)
Clinical Cancer Research
, vol.15
, Issue.17
, pp. 5308-5316
-
-
White, E.1
Dipaola, R.S.2
-
94
-
-
33847404337
-
Autophagy gene-dependent clearance of apoptotic cells during embryonic development
-
X. Qu, Z. Zou, Q. Sun, et al., "Autophagy gene-dependent clearance of apoptotic cells during embryonic development, " Cell, vol. 128, no. 5, pp. 931-946, 2007.
-
(2007)
Cell
, vol.128
, Issue.5
, pp. 931-946
-
-
Qu, X.1
Zou, Z.2
Sun, Q.3
-
95
-
-
78751672975
-
Autophagy in immunity and inflammation
-
B. Levine, N. Mizushima, and H. W. Virgin, "Autophagy in immunity and inflammation, " Nature, vol. 469, no. 7330, pp. 323-335, 2011.
-
(2011)
Nature
, vol.469
, Issue.7330
, pp. 323-335
-
-
Levine, B.1
Mizushima, N.2
Virgin, H.W.3
-
96
-
-
56749170677
-
Autophagic cell death: The story of a misnomer
-
G. Kroemer and B. Levine, "Autophagic cell death: the story of a misnomer, " Nature Reviews Molecular Cell Biology, vol. 9, no. 12, pp. 1004-1010, 2008.
-
(2008)
Nature Reviews Molecular Cell Biology
, vol.9
, Issue.12
, pp. 1004-1010
-
-
Kroemer, G.1
Levine, B.2
-
97
-
-
79953306808
-
Oncogenic Ras-induced expression of Noxa and Beclin-1 promotes autophagic cell death and limits clonogenic survival
-
M. Elgendy, C. Sheridan, G. Brumatti, and S. J. Martin, "Oncogenic Ras-induced expression of Noxa and Beclin-1 promotes autophagic cell death and limits clonogenic survival, "Molecular Cell, vol. 42, no. 1, pp. 23-35, 2011.
-
(2011)
Molecular Cell
, vol.42
, Issue.1
, pp. 23-35
-
-
Elgendy, M.1
Sheridan, C.2
Brumatti, G.3
Martin, S.J.4
-
98
-
-
77954225200
-
Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity
-
Y. Zhao, J. Yang, W. Liao, et al., "Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity, " Nature Cell Biology, vol. 12, no. 7, pp. 665-675, 2010.
-
(2010)
Nature Cell Biology
, vol.12
, Issue.7
, pp. 665-675
-
-
Zhao, Y.1
Yang, J.2
Liao, W.3
-
99
-
-
77957652556
-
Anti-neoplastic activity of the cytosolic FoxO1 results from autophagic cell death
-
Y. Zhao, L. Wang, J. Yang, et al., "Anti-neoplastic activity of the cytosolic FoxO1 results from autophagic cell death, " Autophagy, vol. 6, no. 7, pp. 988-990, 2010.
-
(2010)
Autophagy
, vol.6
, Issue.7
, pp. 988-990
-
-
Zhao, Y.1
Wang, L.2
Yang, J.3
-
100
-
-
64349123107
-
Autophagy mediates themitotic senescence transition
-
A. R. J. Young, M. Narita, M. Ferreira, et al., "Autophagy mediates themitotic senescence transition, " Genes and Development, vol. 23, no. 7, pp. 798-803, 2009.
-
(2009)
Genes and Development
, vol.23
, Issue.7
, pp. 798-803
-
-
Young, A.R.J.1
Narita, M.2
Ferreira, M.3
-
101
-
-
80053634368
-
The dynamic nature of autophagy in cancer
-
A. C. Kimmelman, "The dynamic nature of autophagy in cancer, " Genes and Development, vol. 25, no. 19, pp. 1999-2010, 2011.
-
(2011)
Genes and Development
, vol.25
, Issue.19
, pp. 1999-2010
-
-
Kimmelman, A.C.1
-
102
-
-
84869214214
-
The autophagy-senescence connection in chemotherapy: Must tumor cells (self) eat before they sleep
-
R. W. Goehe, X. Di, K. Sharma, et al., "The autophagy-senescence connection in chemotherapy: must tumor cells (self) eat before they sleep, " Journal of Pharmacology and ExperimentalTherapeutics, vol. 343, no. 3, pp. 763-778, 2012.
-
(2012)
Journal of Pharmacology and ExperimentalTherapeutics
, vol.343
, Issue.3
, pp. 763-778
-
-
Goehe, R.W.1
Di, X.2
Sharma, K.3
-
103
-
-
84891523851
-
Autophagy and senescence in cancer therapy
-
D. A. Gewirtz, "Autophagy and senescence in cancer therapy., " Journal of cellular physiology, vol. 229, no. 1, pp. 6-9, 2014.
-
(2014)
Journal of Cellular Physiology
, vol.229
, Issue.1
, pp. 6-9
-
-
Gewirtz, D.A.1
-
104
-
-
45849130495
-
Ras oncogenes: Split personalities
-
A. E. Karnoub and R. A. Weinberg, "Ras oncogenes: split personalities, " Nature ReviewsMolecular Cell Biology, vol. 9, no. 7, pp. 517-531, 2008.
-
(2008)
Nature ReviewsMolecular Cell Biology
, vol.9
, Issue.7
, pp. 517-531
-
-
Karnoub, A.E.1
Weinberg, R.A.2
-
105
-
-
77955635233
-
Cancer statistics, 2010
-
A. Jemal, R. Siegel, J. Xu, and E. Ward, "Cancer statistics, 2010, " CA Cancer Journal for Clinicians, vol. 60, no. 5, pp. 277-300, 2010.
-
(2010)
CA Cancer Journal for Clinicians
, vol.60
, Issue.5
, pp. 277-300
-
-
Jemal, A.1
Siegel, R.2
Xu, J.3
Ward, E.4
-
106
-
-
50149095124
-
Autophagy is activated in pancreatic cancer cells and correlates with poor patient outcome
-
S. Fujii, S. Mitsunaga, M. Yamazaki, et al., "Autophagy is activated in pancreatic cancer cells and correlates with poor patient outcome, " Cancer Science, vol. 99, no. 9, pp. 1813-1819, 2008.
-
(2008)
Cancer Science
, vol.99
, Issue.9
, pp. 1813-1819
-
-
Fujii, S.1
Mitsunaga, S.2
Yamazaki, M.3
-
107
-
-
84905499163
-
Autophagy is critical for pancreatic tumor growth and progression in tumors with p53 alterations
-
A. Yang, N. V. Rajeshkumar, X. Wang, et al., "Autophagy is critical for pancreatic tumor growth and progression in tumors with p53 alterations, " Cancer Discovery, vol. 4, no. 8, pp. 905-913, 2014.
-
(2014)
Cancer Discovery
, vol.4
, Issue.8
, pp. 905-913
-
-
Yang, A.1
Rajeshkumar, N.V.2
Wang, X.3
-
108
-
-
84890432985
-
P53 status determines the role of autophagy in pancreatic tumour development
-
M. T. Rosenfeldt, J. O'Prey, J. P. Morton, et al., "P53 status determines the role of autophagy in pancreatic tumour development, " Nature, vol. 504, no. 7479, pp. 296-300, 2013.
-
(2013)
Nature
, vol.504
, Issue.7479
, pp. 296-300
-
-
Rosenfeldt, M.T.1
O'Prey, J.2
Morton, J.P.3
-
109
-
-
78751511180
-
Autophagy facilitates glycolysis during Ras-mediated oncogenic transformation
-
R. Lock, S. Roy, C. M. Kenific, et al., "Autophagy facilitates glycolysis during Ras-mediated oncogenic transformation, " Molecular Biology of the Cell, vol. 22, no. 2, pp. 165-178, 2011.
-
(2011)
Molecular Biology of the Cell
, vol.22
, Issue.2
, pp. 165-178
-
-
Lock, R.1
Roy, S.2
Kenific, C.M.3
-
110
-
-
78149341677
-
Oncogenic KRAS modulates mitochondrial metabolism in human colon cancer cells by inducing HIF-1α and HIF-2α target genes
-
article 293
-
S. Y. Chun, C. Johnson, J. G. Washburn, M. R. Cruz-Correa, D. T. Dang, and L. H. Dang, "Oncogenic KRAS modulates mitochondrial metabolism in human colon cancer cells by inducing HIF-1α and HIF-2α target genes, " Molecular Cancer, vol. 9, article 293, 2010.
-
(2010)
Molecular Cancer
, vol.9
-
-
Chun, S.Y.1
Johnson, C.2
Washburn, J.G.3
Cruz-Correa, M.R.4
Dang, D.T.5
Dang, L.H.6
-
111
-
-
58649110598
-
Oncogenic B-RAF negatively regulates the tumor suppressor LKB1 to promote melanoma cell proliferation
-
B. Zheng, J. H. Jeong, J. M. Asara, et al., "Oncogenic B-RAF negatively regulates the tumor suppressor LKB1 to promote melanoma cell proliferation, " Molecular Cell, vol. 33, no. 2, pp. 237-247, 2009.
-
(2009)
Molecular Cell
, vol.33
, Issue.2
, pp. 237-247
-
-
Zheng, B.1
Jeong, J.H.2
Asara, J.M.3
-
112
-
-
80051622129
-
H-ras Up-regulates expression of BNIP3
-
W. Kalas, E. Swiderek, A. Rapak, M. Kopij, J. Rak, and L. Strzadala, "H-ras Up-regulates expression of BNIP3, " Anticancer Research, vol. 31, no. 9, pp. 2869-2875, 2011.
-
(2011)
Anticancer Research
, vol.31
, Issue.9
, pp. 2869-2875
-
-
Kalas, W.1
Swiderek, E.2
Rapak, A.3
Kopij, M.4
Rak, J.5
Strzadala, L.6
-
113
-
-
84855439046
-
Ras-related tumorigenesis is suppressed by BNIP3-mediated autophagy through inhibition of cell proliferation
-
S.-Y. Wu, S.-H. Lan, D.-E. Cheng, et al., "Ras-related tumorigenesis is suppressed by BNIP3-mediated autophagy through inhibition of cell proliferation, " Neoplasia, vol. 13, no. 12, pp. 1171-1182, 2011.
-
(2011)
Neoplasia
, vol.13
, Issue.12
, pp. 1171-1182
-
-
Wu, S.-Y.1
Lan, S.-H.2
Cheng, D.-E.3
-
114
-
-
33845920075
-
Activation of Ras up-regulates pro-apoptotic BNIP3 in nitric oxide-induced cell death
-
H.-J. An, O. Maeng, K.-H. Kang, et al., "Activation of Ras up-regulates pro-apoptotic BNIP3 in nitric oxide-induced cell death, " Journal of Biological Chemistry, vol. 281, no. 45, pp. 33939-33948, 2006.
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.45
, pp. 33939-33948
-
-
An, H.-J.1
Maeng, O.2
Kang, K.-H.3
-
115
-
-
79960401862
-
Suppression of autophagy by FIP200 deletion inhibits mammary tumorigenesis
-
H. Wei, S. Wei, B. Gan, X. Peng, W. Zou, and J.-L. Guan, "Suppression of autophagy by FIP200 deletion inhibits mammary tumorigenesis, "Genes and Development, vol. 25, no. 14, pp. 1510-1527, 2011.
-
(2011)
Genes and Development
, vol.25
, Issue.14
, pp. 1510-1527
-
-
Wei, H.1
Wei, S.2
Gan, B.3
Peng, X.4
Zou, W.5
Guan, J.-L.6
-
116
-
-
84875511284
-
Targeting the PyMT oncogene to diversemammary cell populations enhances tumor heterogeneity and generates rare breast cancer subtypes
-
B. A. Smith, D. N. Shelton, C. Kieffer, et al., "Targeting the PyMT oncogene to diversemammary cell populations enhances tumor heterogeneity and generates rare breast cancer subtypes, " Genes and Cancer, vol. 3, no. 9-10, pp. 550-563, 2012.
-
(2012)
Genes and Cancer
, vol.3
, Issue.9-10
, pp. 550-563
-
-
Smith, B.A.1
Shelton, D.N.2
Kieffer, C.3
-
117
-
-
84878129623
-
Autophagy opposes p53-mediated tumor barrier to facilitate tumorigenesis in a model of PALB2-associated hereditary breast cancer
-
Y. Huo, H. Cai, I. Teplova, et al., "Autophagy opposes p53-mediated tumor barrier to facilitate tumorigenesis in a model of PALB2-associated hereditary breast cancer, " Cancer Discovery, vol. 3, no. 8, pp. 894-907, 2013.
-
(2013)
Cancer Discovery
, vol.3
, Issue.8
, pp. 894-907
-
-
Huo, Y.1
Cai, H.2
Teplova, I.3
-
118
-
-
84864960912
-
Autophagy, stress, and cancer metabolism: What doesnt kill you makes you stronger
-
R. Mathew and E. White, "Autophagy, stress, and cancer metabolism: what doesnt kill you makes you stronger, " Cold Spring Harbor Symposia on Quantitative Biology, vol. 76, pp. 389-396, 2011.
-
(2011)
Cold Spring Harbor Symposia on Quantitative Biology
, vol.76
, pp. 389-396
-
-
Mathew, R.1
White, E.2
-
119
-
-
49549094763
-
Caveolin-1: An ambiguous partner in cell signalling and cancer
-
A. F. G. Quest, J. L. Gutierrez-Pajares, and V. A. Torres, "Caveolin-1: an ambiguous partner in cell signalling and cancer, " Journal of Cellular and Molecular Medicine, vol. 12, no. 4, pp. 1130-1150, 2008.
-
(2008)
Journal of Cellular and Molecular Medicine
, vol.12
, Issue.4
, pp. 1130-1150
-
-
Quest, A.F.G.1
Gutierrez-Pajares, J.L.2
Torres, V.A.3
-
120
-
-
2342566404
-
Caveolins, caveolae, and lipid rafts in cellular transport, signaling, and disease
-
A. F. G. Quest, L. Leyton, and M. Parraga, "Caveolins, caveolae, and lipid rafts in cellular transport, signaling, and disease, " Biochemistry and Cell Biology, vol. 82, no. 1, pp. 129-144, 2004.
-
(2004)
Biochemistry and Cell Biology
, vol.82
, Issue.1
, pp. 129-144
-
-
Quest, A.F.G.1
Leyton, L.2
Parraga, M.3
-
121
-
-
84874865781
-
The Caveolin connection to cell death and survival
-
A. F. G. Quest, L. Lobos-Gonzalez, S. Nunez, et al., "The Caveolin connection to cell death and survival, " CurrentMolecular Medicine, vol. 13, no. 2, pp. 266-281, 2013.
-
(2013)
Current Molecular Medicine
, vol.13
, Issue.2
, pp. 266-281
-
-
Quest, A.F.G.1
Lobos-Gonzalez, L.2
Nunez, S.3
-
122
-
-
84879787916
-
E-cadherin determines Caveolin-1 tumor suppression or metastasis enhancing function in melanoma cells
-
L. Lobos-Gonzalez, L. Aguilar, J. Diaz, et al., "E-cadherin determines Caveolin-1 tumor suppression or metastasis enhancing function in melanoma cells, " Pigment Cell and Melanoma Research, vol. 26, no. 4, pp. 555-570, 2013.
-
(2013)
Pigment Cell and Melanoma Research
, vol.26
, Issue.4
, pp. 555-570
-
-
Lobos-Gonzalez, L.1
Aguilar, L.2
Diaz, J.3
-
123
-
-
65249138239
-
Caveolin-1-mediated suppression of cyclooxygenase-2 via a β-catenin-Tcf/Lef-dependent transcriptional mechanism reduced prostagLandin E2 production and survivin expression
-
D. A. Rodriguez, J. C. Tapia, J. G. Fernandez, et al., "Caveolin-1-mediated suppression of cyclooxygenase-2 via a β-catenin-Tcf/Lef-dependent transcriptional mechanism reduced prostagLandin E2 production and survivin expression, " Molecular Biology of the Cell, vol. 20, no. 8, pp. 2297-2310, 2009.
-
(2009)
Molecular Biology of the Cell
, vol.20
, Issue.8
, pp. 2297-2310
-
-
Rodriguez, D.A.1
Tapia, J.C.2
Fernandez, J.G.3
-
124
-
-
33744529908
-
Caveolin-1 controls cell proliferation and cell death by suppressing expression of the inhibitor of apoptosis protein survivin
-
V. A. Torres, J. C. Tapia, D. A. Rodriguez, et al., "Caveolin-1 controls cell proliferation and cell death by suppressing expression of the inhibitor of apoptosis protein survivin, " Journal of Cell Science, vol. 119, part 9, pp. 1812-1823, 2006.
-
(2006)
Journal of Cell Science
, vol.119
, Issue.PART 9
, pp. 1812-1823
-
-
Torres, V.A.1
Tapia, J.C.2
Rodriguez, D.A.3
-
125
-
-
35649009855
-
E-cadherin is required for caveolin-1-mediated down-regulation of the inhibitor of apoptosis protein survivin via reduced β-catenin-Tcf/Lef-dependent transcription
-
V. A. Torres, J. C. Tapia, D. A. Rodriguez, et al., "E-cadherin is required for caveolin-1-mediated down-regulation of the inhibitor of apoptosis protein survivin via reduced β-catenin-Tcf/Lef-dependent transcription, " Molecular and Cellular Biology, vol. 27, no. 21, pp. 7703-7717, 2007.
-
(2007)
Molecular and Cellular Biology
, vol.27
, Issue.21
, pp. 7703-7717
-
-
Torres, V.A.1
Tapia, J.C.2
Rodriguez, D.A.3
-
126
-
-
77956400210
-
Autophagy in cancer associated fibroblasts promotes tumor cell survival: Role of hypoxia, HIF1 induction and NFκB activation in the tumor stromal microenvironment
-
U. E. Martinez-Outschoorn, C. Trimmer, Z. Lin, et al., "Autophagy in cancer associated fibroblasts promotes tumor cell survival: role of hypoxia, HIF1 induction and NFκB activation in the tumor stromal microenvironment, " Cell Cycle, vol. 9, no. 17, pp. 3515-3533, 2010.
-
(2010)
Cell Cycle
, vol.9
, Issue.17
, pp. 3515-3533
-
-
Martinez-Outschoorn, U.E.1
Trimmer, C.2
Lin, Z.3
-
127
-
-
84855434874
-
Caveolin-1 and cancer metabolism in the tumor microenvironment: Markers, models, and mechanisms
-
F. Sotgia, U. E. Martinez-Outschoorn, A. Howell, R. G. Pestell, S. Pavlides, and M. P. Lisanti, "Caveolin-1 and cancer metabolism in the tumor microenvironment: markers, models, and mechanisms, " Annual Review of Pathology:Mechanisms of Disease, vol. 7, pp. 423-467, 2012.
-
(2012)
Annual Review of Pathology: Mechanisms of Disease
, vol.7
, pp. 423-467
-
-
Sotgia, F.1
Martinez-Outschoorn, U.E.2
Howell, A.3
Pestell, R.G.4
Pavlides, S.5
Lisanti, M.P.6
-
128
-
-
84865130004
-
Caveolin-1 increases aerobic glycolysis in colorectal cancers by stimulating HMGA1-mediated GLUT3 transcription
-
T.-K. Ha, N.-G. Her, M.-G. Lee, et al., "Caveolin-1 increases aerobic glycolysis in colorectal cancers by stimulating HMGA1-mediated GLUT3 transcription, " Cancer Research, vol. 72, no. 16, pp. 4097-4109, 2012.
-
(2012)
Cancer Research
, vol.72
, Issue.16
, pp. 4097-4109
-
-
Ha, T.-K.1
Her, N.-G.2
Lee, M.-G.3
-
129
-
-
84896887907
-
Caveolin-1 is a critical determinant of autophagy, metabolic switching, and oxidative stress in vascular endothelium
-
Article ID e87871
-
T. Shiroto, N. Romero, T. Sugiyama, et al., "Caveolin-1 is a critical determinant of autophagy, metabolic switching, and oxidative stress in vascular endothelium, " PLoS ONE, vol. 9, no. 2, Article ID e87871, 2014.
-
(2014)
PLoS ONE
, vol.9
, Issue.2
-
-
Shiroto, T.1
Romero, N.2
Sugiyama, T.3
-
130
-
-
84901698186
-
Interaction of caveolin with ATG12-ATG5 system suppresses autophagy in lung epithelial cells
-
Z.-H. Chen, J.-F. Cao, J.-S. Zhou, et al., "Interaction of caveolin with ATG12-ATG5 system suppresses autophagy in lung epithelial cells, " The American Journal of Physiology: Lung Cellular and Molecular Physiology, vol. 306, no. 11, pp. L1016-L1025, 2014.
-
(2014)
The American Journal of Physiology: Lung Cellular and Molecular Physiology
, vol.306
, Issue.11
, pp. L1016-L1025
-
-
Chen, Z.-H.1
Cao, J.-F.2
Zhou, J.-S.3
-
131
-
-
84905096743
-
Caloric restriction and cancer: Molecular mechanisms and clinical implications
-
O. Meynet and J.-E. Ricci, "Caloric restriction and cancer:molecular mechanisms and clinical implications, " Trends in Molecular Medicine, vol. 20, no. 8, pp. 419-427, 2014.
-
(2014)
Trends in Molecular Medicine
, vol.20
, Issue.8
, pp. 419-427
-
-
Meynet, O.1
Ricci, J.-E.2
-
132
-
-
84898642644
-
Risk of cancer in diabetes: The effect of metformin
-
Article ID 636927
-
M. Malek, R. Aghili, Z. Emami, and M. E. Khamseh, "Risk of cancer in diabetes: the effect of metformin, " ISRN Endocrinology, vol. 2013, Article ID 636927, 9 pages, 2013.
-
(2013)
ISRN Endocrinology
, vol.2013
, pp. 9
-
-
Malek, M.1
Aghili, R.2
Emami, Z.3
Khamseh, M.E.4
|