The energy sensing LKB1-AMPK pathway regulates p27kip1 phosphorylation mediating the decision to enter autophagy or apoptosis

Nature Cell Biology

Volumn 9, Issue 2, 2007, Pages 218-224

  Liang, Jiyong ^a   Shao, Shan H ^b,c   Xu, Zhi Xiang ^a   Hennessy, Bryan ^a   Ding, Zhiyong ^a   Larrea, Michelle ^d   Kondo, Seiji ^a   Dumont, Dan J ^b   Gutterman, Jordan U ^a   Walker, Cheryl L ^c   Slingerland, Joyce M ^d   Mills, Gordon B ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF TEXAS   (United States)

^d UNIVERSITY OF MIAMI   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; ASPARTIC ACID; CYCLIN DEPENDENT KINASE INHIBITOR 1B; GROWTH FACTOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; PROTEIN KINASE LKB1; THREONINE;

AMINO ACID SUBSTITUTION; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER CHEMOTHERAPY; CARCINOGENESIS; CELL CYCLE PROGRESSION; CELL METABOLISM; CELL STRAIN MCF 7; CELL STRESS; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; ENERGY METABOLISM; HUMAN; HUMAN CELL; MELANOMA CELL; METABOLIC STRESS; NUTRIENT CONCENTRATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; SIGNAL TRANSDUCTION; TUMOR CELL; TUMOR GROWTH; WILD TYPE;

APOPTOSIS; AUTOPHAGY; CELL LINE, TUMOR; CYCLIN-DEPENDENT KINASE INHIBITOR P27; ENERGY METABOLISM; HUMANS; MULTIENZYME COMPLEXES; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION;

MAMMALIA;

EID: 33947250696     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/ncb1537     Document Type: Article

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