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Volumn 13, Issue 2, 2013, Pages 266-281

The Caveolin-1 connection to cell death and survival

Author keywords

Caveolin 1; Cell death; Metastasis; Multi drug resistance; Proliferation; Tumor suppression

Indexed keywords


EID: 84874865781     PISSN: 15665240     EISSN: 18755666     Source Type: Journal    
DOI: 10.2174/156652413804810745     Document Type: Article
Times cited : (68)

References (150)
  • 1
    • 0031692336 scopus 로고    scopus 로고
    • The caveolae membrane system
    • Anderson RG. The caveolae membrane system. Annu Rev Biochem 1998; 67: 199-225.
    • (1998) Annu Rev Biochem , vol.67 , pp. 199-225
    • Anderson, R.G.1
  • 2
    • 0030060941 scopus 로고    scopus 로고
    • Molecular cloning of Caveolin-3, a novel member of the Caveolin gene family expressed predominantly in muscle
    • Tang Z, Scherer PE, Okamoto T, et al. Molecular cloning of Caveolin-3, a novel member of the Caveolin gene family expressed predominantly in muscle. J Biol Chem 1996; 271(4): 2255-61.
    • (1996) J Biol Chem , vol.271 , Issue.4 , pp. 2255-2261
    • Tang, Z.1    Scherer, P.E.2    Okamoto, T.3
  • 3
    • 0032489443 scopus 로고    scopus 로고
    • Caveolins, a family of scaffolding proteins for organizing preassembled signaling complexes at the plasma membrane
    • Okamoto T, Schlegel A, Scherer PE, Lisanti MP. Caveolins, a family of scaffolding proteins for organizing preassembled signaling complexes at the plasma membrane. J Biol Chem 1998; 273(10): 5419-22.
    • (1998) J Biol Chem , vol.273 , Issue.10 , pp. 5419-5422
    • Okamoto, T.1    Schlegel, A.2    Scherer, P.E.3    Lisanti, M.P.4
  • 4
    • 0035964954 scopus 로고    scopus 로고
    • Loss of caveolae, vascular dysfunction, and pulmonary defects in Caveolin-1 gene-disrupted mice
    • Drab M, Verkade P, Elger M, et al. Loss of caveolae, vascular dysfunction, and pulmonary defects in Caveolin-1 gene-disrupted mice. Science 2001; 293(5539): 2449-52.
    • (2001) Science , vol.293 , Issue.5539 , pp. 2449-2452
    • Drab, M.1    Verkade, P.2    Elger, M.3
  • 5
    • 0035851197 scopus 로고    scopus 로고
    • Caveolin-1 null mice are viable but show evidence of hyperproliferative and vascular abnormalities
    • Razani B, Engelman JA, Wang XB, et al. Caveolin-1 null mice are viable but show evidence of hyperproliferative and vascular abnormalities. J Biol Chem 2001; 276(41): 38121-38.
    • (2001) J Biol Chem , vol.276 , Issue.41 , pp. 38121-38138
    • Razani, B.1    Engelman, J.A.2    Wang, X.B.3
  • 6
    • 42949174820 scopus 로고    scopus 로고
    • A critical role of cavin (polymerase I and transcript release factor) in caveolae formation and organization
    • Liu L, Pilch PF. A critical role of cavin (polymerase I and transcript release factor) in caveolae formation and organization. J Biol Chem 2008; 283(7): 4314-22.
    • (2008) J Biol Chem , vol.283 , Issue.7 , pp. 4314-4322
    • Liu, L.1    Pilch, P.F.2
  • 7
    • 37649011760 scopus 로고    scopus 로고
    • PTRF-Cavin, a conserved cytoplasmic protein required for caveola formation and function
    • Hill MM, Bastiani M, Luetterforst R, et al. PTRF-Cavin, a conserved cytoplasmic protein required for caveola formation and function. Cell 2008; 132(1): 113-24.
    • (2008) Cell , vol.132 , Issue.1 , pp. 113-124
    • Hill, M.M.1    Bastiani, M.2    Luetterforst, R.3
  • 8
    • 67349244346 scopus 로고    scopus 로고
    • SRBC/cavin-3 is a Caveolin adapter protein that regulates caveolae function
    • McMahon KA, Zajicek H, Li WP, et al. SRBC/cavin-3 is a Caveolin adapter protein that regulates caveolae function. EMBO J 2009; 28(8): 1001-15.
    • (2009) EMBO J , vol.28 , Issue.8 , pp. 1001-1015
    • McMahon, K.A.1    Zajicek, H.2    Li, W.P.3
  • 9
    • 67650072744 scopus 로고    scopus 로고
    • SDPR induces membrane curvature and functions in the formation of caveolae
    • Hansen CG, Bright NA, Howard G, Nichols BJ. SDPR induces membrane curvature and functions in the formation of caveolae. Nat Cell Biol 2009; 11(7): 807-14.
    • (2009) Nat Cell Biol , vol.11 , Issue.7 , pp. 807-814
    • Hansen, C.G.1    Bright, N.A.2    Howard, G.3    Nichols, B.J.4
  • 10
    • 65649122726 scopus 로고    scopus 로고
    • Lattices, rafts, and scaffolds: Domain regulation of receptor signaling at the plasma membrane
    • Lajoie P, Goetz JG, Dennis JW, Nabi IR. Lattices, rafts, and scaffolds: domain regulation of receptor signaling at the plasma membrane. J Cell Biol 2009; 185(3): 381-5.
    • (2009) J Cell Biol , vol.185 , Issue.3 , pp. 381-385
    • Lajoie, P.1    Goetz, J.G.2    Dennis, J.W.3    Nabi, I.R.4
  • 11
    • 49549094763 scopus 로고    scopus 로고
    • Caveolin-1: An ambiguous partner in cell signalling and cancer
    • Quest AF, Gutierrez-Pajares JL, Torres VA. Caveolin-1: an ambiguous partner in cell signalling and cancer. J Cell Mol Med 2008; 12(4): 1130-50.
    • (2008) J Cell Mol Med , vol.12 , Issue.4 , pp. 1130-1150
    • Quest, A.F.1    Gutierrez-Pajares, J.L.2    Torres, V.A.3
  • 12
    • 0028920139 scopus 로고
    • Caveolin is palmitoylated on multiple cysteine residues. Palmitoylation is not necessary for localization of Caveolin to caveolae
    • Dietzen DJ, Hastings WR, Lublin DM. Caveolin is palmitoylated on multiple cysteine residues. Palmitoylation is not necessary for localization of Caveolin to caveolae. J Biol Chem 1995; 270(12): 6838-42.
    • (1995) J Biol Chem , vol.270 , Issue.12 , pp. 6838-6842
    • Dietzen, D.J.1    Hastings, W.R.2    Lublin, D.M.3
  • 13
    • 0030591426 scopus 로고    scopus 로고
    • Oligomerization of VIP21-Caveolin in vitro is stabilized by long chain fatty acylation or cholesterol
    • Monier S, Dietzen DJ, Hastings WR, Lublin DM, Kurzchalia TV. Oligomerization of VIP21-Caveolin in vitro is stabilized by long chain fatty acylation or cholesterol. FEBS Lett 1996; 388(2-3): 143-9.
    • (1996) FEBS Lett , vol.388 , Issue.2-3 , pp. 143-149
    • Monier, S.1    Dietzen, D.J.2    Hastings, W.R.3    Lublin, D.M.4    Kurzchalia, T.V.5
  • 14
    • 0034532164 scopus 로고    scopus 로고
    • Caveolin-3 directly interacts with the C-terminal tail of beta -dystroglycan. Identification of a central WW-like domain within Caveolin family members
    • Sotgia F, Lee JK, Das K, et al. Caveolin-3 directly interacts with the C-terminal tail of beta -dystroglycan. Identification of a central WW-like domain within Caveolin family members. J Biol Chem 2000; 275(48): 38048-58.
    • (2000) J Biol Chem , vol.275 , Issue.48 , pp. 38048-38058
    • Sotgia, F.1    Lee, J.K.2    Das, K.3
  • 15
    • 0036403111 scopus 로고    scopus 로고
    • Caveolae and caveolae-like membrane domains in cellular signaling and disease: Identification of downstream targets for the tumor suppressor protein Caveolin-1
    • Bender F, Montoya M, Monardes V, Leyton L, Quest AF. Caveolae and caveolae-like membrane domains in cellular signaling and disease: identification of downstream targets for the tumor suppressor protein Caveolin-1. Biol Res 2002; 35(2): 151-67.
    • (2002) Biol Res , vol.35 , Issue.2 , pp. 151-167
    • Bender, F.1    Montoya, M.2    Monardes, V.3    Leyton, L.4    Quest, A.F.5
  • 16
    • 2942595764 scopus 로고    scopus 로고
    • Cell type-specific occurrence of Caveolin-1alpha and -1beta in the lung caused by expression of distinct mRNAs
    • Kogo H, Aiba T, Fujimoto T. Cell type-specific occurrence of Caveolin-1alpha and -1beta in the lung caused by expression of distinct mRNAs. J Biol Chem 2004; 279(24): 25574-81.
    • (2004) J Biol Chem , vol.279 , Issue.24 , pp. 25574-25581
    • Kogo, H.1    Aiba, T.2    Fujimoto, T.3
  • 17
    • 9144229688 scopus 로고    scopus 로고
    • Caveolin-1 null (-/-) mice show dramatic reductions in life span
    • Park DS, Cohen AW, Frank PG, et al. Caveolin-1 null (-/-) mice show dramatic reductions in life span. Biochemistry 2003; 42(51): 15124-31.
    • (2003) Biochemistry , vol.42 , Issue.51 , pp. 15124-15131
    • Park, D.S.1    Cohen, A.W.2    Frank, P.G.3
  • 18
    • 33748773325 scopus 로고    scopus 로고
    • Caveolin-1 is essential for liver regeneration
    • Fernandez MA, Albor C, Ingelmo-Torres M, et al. Caveolin-1 is essential for liver regeneration. Science 2006; 313(5793): 1628-32.
    • (2006) Science , vol.313 , Issue.5793 , pp. 1628-1632
    • Fernandez, M.A.1    Albor, C.2    Ingelmo-Torres, M.3
  • 19
    • 52549127487 scopus 로고    scopus 로고
    • Caveolin-1 in tumor progression: The good, the bad and the ugly
    • Goetz JG, Lajoie P, Wiseman SM, Nabi IR. Caveolin-1 in tumor progression: the good, the bad and the ugly. Cancer Metastasis Rev 2008; 27(4): 715-35.
    • (2008) Cancer Metastasis Rev , vol.27 , Issue.4 , pp. 715-735
    • Goetz, J.G.1    Lajoie, P.2    Wiseman, S.M.3    Nabi, I.R.4
  • 20
    • 33645216741 scopus 로고    scopus 로고
    • Biogenesis of caveolae: A structural model for Caveolin-induced domain formation
    • Parton RG, Hanzal-Bayer M, Hancock JF. Biogenesis of caveolae: a structural model for Caveolin-induced domain formation. J Cell Sci 2006; 119(Pt 5): 787-96.
    • (2006) J Cell Sci , vol.119 , Issue.Pt 5 , pp. 787-796
    • Parton, R.G.1    Hanzal-Bayer, M.2    Hancock, J.F.3
  • 21
    • 78049499223 scopus 로고    scopus 로고
    • Revisiting Caveolin trafficking: The end of the caveosome
    • Parton RG, Howes MT. Revisiting Caveolin trafficking: the end of the caveosome. J Cell Biol; 191(3): 439-41.
    • J Cell Biol , vol.191 , Issue.3 , pp. 439-441
    • Parton, R.G.1    Howes, M.T.2
  • 22
    • 78049508213 scopus 로고    scopus 로고
    • Caveolin-1 is ubiquitinated and targeted to intralumenal vesicles in endolysosomes for degradation
    • Hayer A, Stoeber M, Ritz D, Engel S, Meyer HH, Helenius A. Caveolin-1 is ubiquitinated and targeted to intralumenal vesicles in endolysosomes for degradation. J Cell Biol 2010; 191(3): 615-29.
    • (2010) J Cell Biol , vol.191 , Issue.3 , pp. 615-629
    • Hayer, A.1    Stoeber, M.2    Ritz, D.3    Engel, S.4    Meyer, H.H.5    Helenius, A.6
  • 23
    • 0024317054 scopus 로고
    • Tyrosine phosphorylation of a 22-kDa protein is correlated with transformation by Rous sarcoma virus
    • Glenney JR, Jr. Tyrosine phosphorylation of a 22-kDa protein is correlated with transformation by Rous sarcoma virus. J Biol Chem 1989; 264(34): 20163-6.
    • (1989) J Biol Chem , vol.264 , Issue.34 , pp. 20163-20166
    • Glenney Jr., J.R.1
  • 24
    • 0024382542 scopus 로고
    • Novel tyrosine kinase substrates from Rous sarcoma virus-transformed cells are present in the membrane skeleton
    • Glenney JR, Jr., Zokas L. Novel tyrosine kinase substrates from Rous sarcoma virus-transformed cells are present in the membrane skeleton. J Cell Biol 1989; 108(6): 2401-8.
    • (1989) J Cell Biol , vol.108 , Issue.6 , pp. 2401-2408
    • Glenney Jr., J.R.1    Zokas, L.2
  • 25
    • 0026454933 scopus 로고
    • Sequence and expression of Caveolin, a protein component of caveolae plasma membrane domains phosphorylated on tyrosine in Rous sarcoma virus-transformed fibroblasts
    • Glenney JR, Jr., Soppet D. Sequence and expression of Caveolin, a protein component of caveolae plasma membrane domains phosphorylated on tyrosine in Rous sarcoma virus-transformed fibroblasts. Proc Natl Acad Sci USA 1992; 89(21): 10517-21.
    • (1992) Proc Natl Acad Sci USA , vol.89 , Issue.21 , pp. 10517-10521
    • Glenney Jr., J.R.1    Soppet, D.2
  • 26
    • 0028953271 scopus 로고
    • Reduction of Caveolin and caveolae in oncogenically transformed cells
    • Koleske AJ, Baltimore D, Lisanti MP. Reduction of Caveolin and caveolae in oncogenically transformed cells. Proc Natl Acad Sci USA 1995; 92(5): 1381-5.
    • (1995) Proc Natl Acad Sci USA , vol.92 , Issue.5 , pp. 1381-1385
    • Koleske, A.J.1    Baltimore, D.2    Lisanti, M.P.3
  • 27
    • 0030960332 scopus 로고    scopus 로고
    • Recombinant expression of Caveolin-1 in oncogenically transformed cells abrogates anchorageindependent growth
    • Engelman JA, Wykoff CC, Yasuhara S, Song KS, Okamoto T, Lisanti MP. Recombinant expression of Caveolin-1 in oncogenically transformed cells abrogates anchorageindependent growth. J Biol Chem 1997; 272(26): 16374-81.
    • (1997) J Biol Chem , vol.272 , Issue.26 , pp. 16374-16381
    • Engelman, J.A.1    Wykoff, C.C.2    Yasuhara, S.3    Song, K.S.4    Okamoto, T.5    Lisanti, M.P.6
  • 28
    • 0034725590 scopus 로고    scopus 로고
    • Caveolin-1 expression inhibits Wnt/beta-catenin/Lef-1 signaling by recruiting beta-catenin to caveolae membrane domains
    • Galbiati F, Volonte D, Brown AM, et al. Caveolin-1 expression inhibits Wnt/beta-catenin/Lef-1 signaling by recruiting beta-catenin to caveolae membrane domains. J Biol Chem 2000; 275(30): 23368-77.
    • (2000) J Biol Chem , vol.275 , Issue.30 , pp. 23368-23377
    • Galbiati, F.1    Volonte, D.2    Brown, A.M.3
  • 30
    • 0032546319 scopus 로고    scopus 로고
    • Tumor cell growth inhibition by Caveolin re-expression in human breast cancer cells
    • Lee SW, Reimer CL, Oh P, Campbell DB, Schnitzer JE. Tumor cell growth inhibition by Caveolin re-expression in human breast cancer cells. Oncogene 1998; 16(11): 1391-7.
    • (1998) Oncogene , vol.16 , Issue.11 , pp. 1391-1397
    • Lee, S.W.1    Reimer, C.L.2    Oh, P.3    Campbell, D.B.4    Schnitzer, J.E.5
  • 31
    • 0034667394 scopus 로고    scopus 로고
    • Caveolin-1 levels are down-regulated in human colon tumors, and ectopic expression of Caveolin-1 in colon carcinoma cell lines reduces cell tumorigenicity
    • Bender FC, Reymond MA, Bron C, Quest AF. Caveolin-1 levels are down-regulated in human colon tumors, and ectopic expression of Caveolin-1 in colon carcinoma cell lines reduces cell tumorigenicity. Cancer Res 2000; 60(20): 5870-8.
    • (2000) Cancer Res , vol.60 , Issue.20 , pp. 5870-5878
    • Bender, F.C.1    Reymond, M.A.2    Bron, C.3    Quest, A.F.4
  • 32
    • 0035149144 scopus 로고    scopus 로고
    • Caveolin-1 is down-regulated in human ovarian carcinoma and acts as a candidate tumor suppressor gene
    • Wiechen K, Diatchenko L, Agoulnik A, et al. Caveolin-1 is down-regulated in human ovarian carcinoma and acts as a candidate tumor suppressor gene. Am J Pathol 2001; 159(5): 1635-43.
    • (2001) Am J Pathol , vol.159 , Issue.5 , pp. 1635-1643
    • Wiechen, K.1    Diatchenko, L.2    Agoulnik, A.3
  • 33
    • 0038751964 scopus 로고    scopus 로고
    • Absence of Caveolin-1 sensitizes mouse skin to carcinogen-induced epidermal hyperplasia and tumor formation
    • Capozza F, Williams TM, Schubert W, et al. Absence of Caveolin-1 sensitizes mouse skin to carcinogen-induced epidermal hyperplasia and tumor formation. Am J Pathol 2003; 162(6): 2029-39.
    • (2003) Am J Pathol , vol.162 , Issue.6 , pp. 2029-2039
    • Capozza, F.1    Williams, T.M.2    Schubert, W.3
  • 34
    • 0037342807 scopus 로고    scopus 로고
    • Loss of Caveolin-1 gene expression accelerates the development of dysplastic mammary lesions in tumor-prone transgenic mice
    • Williams TM, Cheung MW, Park DS, et al. Loss of Caveolin-1 gene expression accelerates the development of dysplastic mammary lesions in tumor-prone transgenic mice. Mol Biol Cell 2003; 14(3): 1027-42.
    • (2003) Mol Biol Cell , vol.14 , Issue.3 , pp. 1027-1042
    • Williams, T.M.1    Cheung, M.W.2    Park, D.S.3
  • 35
    • 34047251876 scopus 로고    scopus 로고
    • Caveolin-1-deficient mice have increased tumor microvascular permeability, angiogenesis, and growth
    • Lin MI, Yu J, Murata T, Sessa WC. Caveolin-1-deficient mice have increased tumor microvascular permeability, angiogenesis, and growth. Cancer Res 2007; 67(6): 2849-56.
    • (2007) Cancer Res , vol.67 , Issue.6 , pp. 2849-2856
    • Lin, M.I.1    Yu, J.2    Murata, T.3    Sessa, W.C.4
  • 36
    • 17344363636 scopus 로고    scopus 로고
    • Reciprocal regulation of neu tyrosine kinase activity and Caveolin-1 protein expression in vitro and in vivo. Implications for human breast cancer
    • Engelman JA, Lee RJ, Karnezis A, et al. Reciprocal regulation of neu tyrosine kinase activity and Caveolin-1 protein expression in vitro and in vivo. Implications for human breast cancer. J Biol Chem 1998; 273(32): 20448-55.
    • (1998) J Biol Chem , vol.273 , Issue.32 , pp. 20448-20455
    • Engelman, J.A.1    Lee, R.J.2    Karnezis, A.3
  • 37
    • 0035866759 scopus 로고    scopus 로고
    • Invasion activating Caveolin-1 mutation in human scirrhous breast cancers
    • Hayashi K, Matsuda S, Machida K, et al. Invasion activating Caveolin-1 mutation in human scirrhous breast cancers. Cancer Res 2001; 61(6): 2361-4.
    • (2001) Cancer Res , vol.61 , Issue.6 , pp. 2361-2364
    • Hayashi, K.1    Matsuda, S.2    Machida, K.3
  • 38
    • 0036791604 scopus 로고    scopus 로고
    • Caveolin-1 mutations (P132L and null) and the pathogenesis of breast cancer: Caveolin-1 (P132L) behaves in a dominant-negative manner and Caveolin-1 (-/-) null mice show mammary epithelial cell hyperplasia
    • Lee H, Park DS, Razani B, Russell RG, Pestell RG, Lisanti MP. Caveolin-1 mutations (P132L and null) and the pathogenesis of breast cancer: Caveolin-1 (P132L) behaves in a dominant-negative manner and Caveolin-1 (-/-) null mice show mammary epithelial cell hyperplasia. Am J Pathol 2002; 161(4): 1357-69.
    • (2002) Am J Pathol , vol.161 , Issue.4 , pp. 1357-1369
    • Lee, H.1    Park, D.S.2    Razani, B.3    Russell, R.G.4    Pestell, R.G.5    Lisanti, M.P.6
  • 39
    • 33744776333 scopus 로고    scopus 로고
    • Caveolin-1 mutations in human breast cancer: Functional association with estrogen receptor alpha-positive status
    • Li T, Sotgia F, Vuolo MA, et al. Caveolin-1 mutations in human breast cancer: functional association with estrogen receptor alpha-positive status. Am J Pathol 2006; 168(6): 1998-2013.
    • (2006) Am J Pathol , vol.168 , Issue.6 , pp. 1998-2013
    • Li, T.1    Sotgia, F.2    Vuolo, M.A.3
  • 40
    • 78649859750 scopus 로고    scopus 로고
    • Regulation of lung cancer cell migration and invasion by reactive oxygen species and Caveolin-1
    • Luanpitpong S, Talbott SJ, Rojanasakul Y, et al. Regulation of lung cancer cell migration and invasion by reactive oxygen species and Caveolin-1. J Biol Chem 2010; 285(50): 38832-40.
    • (2010) J Biol Chem , vol.285 , Issue.50 , pp. 38832-38840
    • Luanpitpong, S.1    Talbott, S.J.2    Rojanasakul, Y.3
  • 41
    • 37349060696 scopus 로고    scopus 로고
    • Caveolin-1 secreting LNCaP cells induce tumor growth of Caveolin-1 negative LNCaP cells in vivo
    • Bartz R, Zhou J, Hsieh JT, Ying Y, Li W, Liu P. Caveolin-1 secreting LNCaP cells induce tumor growth of Caveolin-1 negative LNCaP cells in vivo. Int J Cancer 2008; 122(3): 520-5.
    • (2008) Int J Cancer , vol.122 , Issue.3 , pp. 520-525
    • Bartz, R.1    Zhou, J.2    Hsieh, J.T.3    Ying, Y.4    Li, W.5    Liu, P.6
  • 43
    • 0031763007 scopus 로고    scopus 로고
    • Upregulation of Caveolin-1 and caveolae organelles in Taxolresistant A549 cells
    • Yang CP, Galbiati F, Volonte D, Horwitz SB, Lisanti MP. Upregulation of Caveolin-1 and caveolae organelles in Taxolresistant A549 cells. FEBS Lett 1998; 439(3): 368-72.
    • (1998) FEBS Lett , vol.439 , Issue.3 , pp. 368-372
    • Yang, C.P.1    Galbiati, F.2    Volonte, D.3    Horwitz, S.B.4    Lisanti, M.P.5
  • 44
    • 0031872767 scopus 로고    scopus 로고
    • Elevated expression of Caveolin is associated with prostate and breast cancer
    • Yang G, Truong LD, Timme TL, et al. Elevated expression of Caveolin is associated with prostate and breast cancer. Clin Cancer Res 1998; 4(8): 1873-80.
    • (1998) Clin Cancer Res , vol.4 , Issue.8 , pp. 1873-1880
    • Yang, G.1    Truong, L.D.2    Timme, T.L.3
  • 45
    • 0035031405 scopus 로고    scopus 로고
    • Cell-specific targeting of Caveolin-1 to caveolae, secretory vesicles, cytoplasm or mitochondria
    • Li WP, Liu P, Pilcher BK, Anderson RG. Cell-specific targeting of Caveolin-1 to caveolae, secretory vesicles, cytoplasm or mitochondria. J Cell Sci 2001; 114(Pt 7): 1397-408.
    • (2001) J Cell Sci , vol.114 , Issue.Pt 7 , pp. 1397-1408
    • Li, W.P.1    Liu, P.2    Pilcher, B.K.3    Anderson, R.G.4
  • 46
    • 0035872436 scopus 로고    scopus 로고
    • Secreted Caveolin-1 stimulates cell survival/clonal growth and contributes to metastasis in androgen-insensitive prostate cancer
    • Tahir SA, Yang G, Ebara S, et al. Secreted Caveolin-1 stimulates cell survival/clonal growth and contributes to metastasis in androgen-insensitive prostate cancer. Cancer Res 2001; 61(10): 3882-5.
    • (2001) Cancer Res , vol.61 , Issue.10 , pp. 3882-3885
    • Tahir, S.A.1    Yang, G.2    Ebara, S.3
  • 47
    • 0032484149 scopus 로고    scopus 로고
    • Up-regulation of caveolae and caveolar constituents in multidrug-resistant cancer cells
    • Lavie Y, Fiucci G, Liscovitch M. Up-regulation of caveolae and caveolar constituents in multidrug-resistant cancer cells. J Biol Chem 1998; 273(49): 32380-3.
    • (1998) J Biol Chem , vol.273 , Issue.49 , pp. 32380-32383
    • Lavie, Y.1    Fiucci, G.2    Liscovitch, M.3
  • 48
    • 0037018405 scopus 로고    scopus 로고
    • Caveolin-1 inhibits anchorage-independent growth, anoikis and invasiveness in MCF-7 human breast cancer cells
    • Fiucci G, Ravid D, Reich R, Liscovitch M. Caveolin-1 inhibits anchorage-independent growth, anoikis and invasiveness in MCF-7 human breast cancer cells. Oncogene 2002; 21(15): 2365-75.
    • (2002) Oncogene , vol.21 , Issue.15 , pp. 2365-2375
    • Fiucci, G.1    Ravid, D.2    Reich, R.3    Liscovitch, M.4
  • 49
    • 33748072402 scopus 로고    scopus 로고
    • Caveolin-1 inhibits anoikis and promotes survival signaling in cancer cells
    • Ravid D, Maor S, Werner H, Liscovitch M. Caveolin-1 inhibits anoikis and promotes survival signaling in cancer cells. Adv Enzyme Regul 2006; 46: 163-75.
    • (2006) Adv Enzyme Regul , vol.46 , pp. 163-175
    • Ravid, D.1    Maor, S.2    Werner, H.3    Liscovitch, M.4
  • 50
    • 38449093572 scopus 로고    scopus 로고
    • The overexpression of Caveolin-1 and Caveolin-2 correlates with a poor prognosis and tumor progression in esophageal squamous cell carcinoma
    • Ando T, Ishiguro H, Kimura M, et al. The overexpression of Caveolin-1 and Caveolin-2 correlates with a poor prognosis and tumor progression in esophageal squamous cell carcinoma. Oncol Rep 2007; 18(3): 601-9.
    • (2007) Oncol Rep , vol.18 , Issue.3 , pp. 601-609
    • Ando, T.1    Ishiguro, H.2    Kimura, M.3
  • 51
    • 37549016730 scopus 로고    scopus 로고
    • Caveolin-1 expression is significantly associated with drug resistance and poor prognosis in advanced non-small cell lung cancer patients treated with gemcitabine-based chemotherapy
    • Ho CC, Kuo SH, Huang PH, Huang HY, Yang CH, Yang PC. Caveolin-1 expression is significantly associated with drug resistance and poor prognosis in advanced non-small cell lung cancer patients treated with gemcitabine-based chemotherapy. Lung Cancer 2008; 59(1): 105-10.
    • (2008) Lung Cancer , vol.59 , Issue.1 , pp. 105-110
    • Ho, C.C.1    Kuo, S.H.2    Huang, P.H.3    Huang, H.Y.4    Yang, C.H.5    Yang, P.C.6
  • 52
    • 33846288318 scopus 로고    scopus 로고
    • Caveolin 1 is overexpressed and amplified in a subset of basal-like and metaplastic breast carcinomas: A morphologic, ultrastructural, immunohistochemical, and in situ hybridization analysis
    • Savage K, Lambros MB, Robertson D, et al. Caveolin 1 is overexpressed and amplified in a subset of basal-like and metaplastic breast carcinomas: a morphologic, ultrastructural, immunohistochemical, and in situ hybridization analysis. Clin Cancer Res 2007; 13(1): 90-101.
    • (2007) Clin Cancer Res , vol.13 , Issue.1 , pp. 90-101
    • Savage, K.1    Lambros, M.B.2    Robertson, D.3
  • 53
    • 0041969715 scopus 로고    scopus 로고
    • Differential Caveolin-1 polarization in endothelial cells during migration in two and three dimensions
    • Parat MO, Anand-Apte B, Fox PL. Differential Caveolin-1 polarization in endothelial cells during migration in two and three dimensions. Mol Biol Cell 2003; 14(8): 3156-68.
    • (2003) Mol Biol Cell , vol.14 , Issue.8 , pp. 3156-3168
    • Parat, M.O.1    Anand-Apte, B.2    Fox, P.L.3
  • 54
    • 13544252448 scopus 로고    scopus 로고
    • Loss of Caveolin-1 polarity impedes endothelial cell polarization and directional movement
    • Beardsley A, Fang K, Mertz H, Castranova V, Friend S, Liu J. Loss of Caveolin-1 polarity impedes endothelial cell polarization and directional movement. J Biol Chem 2005; 280(5): 3541-7.
    • (2005) J Biol Chem , vol.280 , Issue.5 , pp. 3541-3547
    • Beardsley, A.1    Fang, K.2    Mertz, H.3    Castranova, V.4    Friend, S.5    Liu, J.6
  • 55
    • 35748948029 scopus 로고    scopus 로고
    • Caveolin-1 polarization in transmigrating endothelial cells requires binding to intermediate filaments
    • Santilman V, Baran J, Anand-Apte B, Evans RM, Parat MO. Caveolin-1 polarization in transmigrating endothelial cells requires binding to intermediate filaments. Angiogenesis 2007; 10(4): 297-305.
    • (2007) Angiogenesis , vol.10 , Issue.4 , pp. 297-305
    • Santilman, V.1    Baran, J.2    Anand-Apte, B.3    Evans, R.M.4    Parat, M.O.5
  • 56
    • 0036841790 scopus 로고    scopus 로고
    • Up-regulated Caveolin-1 accentuates the metastasis capability of lung adenocarcinoma by inducing filopodia formation
    • Ho CC, Huang PH, Huang HY, Chen YH, Yang PC, Hsu SM. Up-regulated Caveolin-1 accentuates the metastasis capability of lung adenocarcinoma by inducing filopodia formation. Am J Pathol 2002; 161(5): 1647-56.
    • (2002) Am J Pathol , vol.161 , Issue.5 , pp. 1647-1656
    • Ho, C.C.1    Huang, P.H.2    Huang, H.Y.3    Chen, Y.H.4    Yang, P.C.5    Hsu, S.M.6
  • 57
    • 0033659710 scopus 로고    scopus 로고
    • Constitutive and growth factor-regulated phosphorylation of Caveolin-1 occurs at the same site (Tyr-14) in vivo: Identification of a c-Src/Cav- 1/Grb7 signaling cassette
    • Lee H, Volonte D, Galbiati F, et al. Constitutive and growth factor-regulated phosphorylation of Caveolin-1 occurs at the same site (Tyr-14) in vivo: identification of a c-Src/Cav- 1/Grb7 signaling cassette. Mol Endocrinol 2000; 14(11): 1750-75.
    • (2000) Mol Endocrinol , vol.14 , Issue.11 , pp. 1750-1775
    • Lee, H.1    Volonte, D.2    Galbiati, F.3
  • 59
    • 0035361376 scopus 로고    scopus 로고
    • Caveolin-1 mediates testosterone-stimulated survival/clonal growth and promotes metastatic activities in prostate cancer cells
    • Li L, Yang G, Ebara S, et al. Caveolin-1 mediates testosterone-stimulated survival/clonal growth and promotes metastatic activities in prostate cancer cells. Cancer Res 2001; 61(11): 4386-92.
    • (2001) Cancer Res , vol.61 , Issue.11 , pp. 4386-4392
    • Li, L.1    Yang, G.2    Ebara, S.3
  • 60
    • 34248191183 scopus 로고    scopus 로고
    • Poor prognosis in breast carcinomas correlates with increased expression of targetable CD146 and c-Met and with proteomic basal-like phenotype
    • Garcia S, Dales JP, Charafe-Jauffret E, et al. Poor prognosis in breast carcinomas correlates with increased expression of targetable CD146 and c-Met and with proteomic basal-like phenotype. Hum Pathol 2007; 38(6): 830-41.
    • (2007) Hum Pathol , vol.38 , Issue.6 , pp. 830-841
    • Garcia, S.1    Dales, J.P.2    Charafe-Jauffret, E.3
  • 61
    • 13644266312 scopus 로고    scopus 로고
    • Caveolin-1 in oncogenic transformation, cancer, and metastasis
    • Williams TM, Lisanti MP. Caveolin-1 in oncogenic transformation, cancer, and metastasis. Am J Physiol Cell Physiol 2005; 288(3): C494-506.
    • (2005) Am J Physiol Cell Physiol , vol.288 , Issue.3
    • Williams, T.M.1    Lisanti, M.P.2
  • 62
    • 0034687690 scopus 로고    scopus 로고
    • Caveolin-1 down-regulates inducible nitric oxide synthase via the proteasome pathway in human colon carcinoma cells
    • Felley-Bosco E, Bender FC, Courjault-Gautier F, Bron C, Quest AF. Caveolin-1 down-regulates inducible nitric oxide synthase via the proteasome pathway in human colon carcinoma cells. Proc Natl Acad Sci USA 2000; 97(26): 14334-9.
    • (2000) Proc Natl Acad Sci USA , vol.97 , Issue.26 , pp. 14334-14339
    • Felley-Bosco, E.1    Bender, F.C.2    Courjault-Gautier, F.3    Bron, C.4    Quest, A.F.5
  • 63
    • 0036402373 scopus 로고    scopus 로고
    • Caveolin-1-mediated post-transcriptional regulation of inducible nitric oxide synthase in human colon carcinoma cells
    • Felley-Bosco E, Bender F, Quest AF. Caveolin-1-mediated post-transcriptional regulation of inducible nitric oxide synthase in human colon carcinoma cells. Biol Res 2002; 35(2): 169-76.
    • (2002) Biol Res , vol.35 , Issue.2 , pp. 169-176
    • Felley-Bosco, E.1    Bender, F.2    Quest, A.F.3
  • 64
    • 0029019438 scopus 로고
    • Insulin stimulates the tyrosine phosphorylation of Caveolin
    • Mastick CC, Brady MJ, Saltiel AR. Insulin stimulates the tyrosine phosphorylation of Caveolin. J Cell Biol 1995; 129(6): 1523-31.
    • (1995) J Cell Biol , vol.129 , Issue.6 , pp. 1523-1531
    • Mastick, C.C.1    Brady, M.J.2    Saltiel, A.R.3
  • 65
    • 0030744872 scopus 로고    scopus 로고
    • Insulin-stimulated tyrosine phosphorylation of Caveolin is specific for the differentiated adipocyte phenotype in 3T3-L1 cells
    • Mastick CC, Saltiel AR. Insulin-stimulated tyrosine phosphorylation of Caveolin is specific for the differentiated adipocyte phenotype in 3T3-L1 cells. J Biol Chem 1997; 272(33): 20706-14.
    • (1997) J Biol Chem , vol.272 , Issue.33 , pp. 20706-20714
    • Mastick, C.C.1    Saltiel, A.R.2
  • 66
    • 0037119387 scopus 로고    scopus 로고
    • The insulin receptor catalyzes the tyrosine phosphorylation of Caveolin-1
    • Kimura A, Mora S, Shigematsu S, Pessin JE, Saltiel AR. The insulin receptor catalyzes the tyrosine phosphorylation of Caveolin-1. J Biol Chem 2002; 277(33): 30153-8.
    • (2002) J Biol Chem , vol.277 , Issue.33 , pp. 30153-30158
    • Kimura, A.1    Mora, S.2    Shigematsu, S.3    Pessin, J.E.4    Saltiel, A.R.5
  • 67
    • 0037088672 scopus 로고    scopus 로고
    • A phosphotyrosinedependent protein interaction screen reveals a role for phosphorylation of Caveolin-1 on tyrosine 14: Recruitment of C-terminal Src kinase
    • Cao H, Courchesne WE, Mastick CC. A phosphotyrosinedependent protein interaction screen reveals a role for phosphorylation of Caveolin-1 on tyrosine 14: recruitment of C-terminal Src kinase. J Biol Chem 2002; 277(11): 8771-4.
    • (2002) J Biol Chem , vol.277 , Issue.11 , pp. 8771-8774
    • Cao, H.1    Courchesne, W.E.2    Mastick, C.C.3
  • 68
    • 1242272011 scopus 로고    scopus 로고
    • Oxidative stress activates both Src-kinases and their negative regulator Csk and induces phosphorylation of two targeting proteins for Csk: Caveolin-1 and paxillin
    • Cao H, Sanguinetti AR, Mastick CC. Oxidative stress activates both Src-kinases and their negative regulator Csk and induces phosphorylation of two targeting proteins for Csk: Caveolin-1 and paxillin. Exp Cell Res 2004; 294(1): 159-71.
    • (2004) Exp Cell Res , vol.294 , Issue.1 , pp. 159-171
    • Cao, H.1    Sanguinetti, A.R.2    Mastick, C.C.3
  • 69
    • 0035896560 scopus 로고    scopus 로고
    • Cellular stress induces the tyrosine phosphorylation of Caveolin-1 (Tyr(14)) via activation of p38 mitogen-activated protein kinase and c- Src kinase. Evidence for caveolae, the actin cytoskeleton, and focal adhesions as mechanical sensors of osmotic stress
    • Volonte D, Galbiati F, Pestell RG, Lisanti MP. Cellular stress induces the tyrosine phosphorylation of Caveolin-1 (Tyr(14)) via activation of p38 mitogen-activated protein kinase and c- Src kinase. Evidence for caveolae, the actin cytoskeleton, and focal adhesions as mechanical sensors of osmotic stress. J Biol Chem 2001; 276(11): 8094-103.
    • (2001) J Biol Chem , vol.276 , Issue.11 , pp. 8094-8103
    • Volonte, D.1    Galbiati, F.2    Pestell, R.G.3    Lisanti, M.P.4
  • 70
    • 10644229956 scopus 로고    scopus 로고
    • Src-mediated tyrosine phosphorylation of Caveolin-1 induces its association with membrane type 1 matrix metalloproteinase
    • Labrecque L, Nyalendo C, Langlois S, et al. Src-mediated tyrosine phosphorylation of Caveolin-1 induces its association with membrane type 1 matrix metalloproteinase. J Biol Chem 2004; 279(50): 52132-40.
    • (2004) J Biol Chem , vol.279 , Issue.50 , pp. 52132-52140
    • Labrecque, L.1    Nyalendo, C.2    Langlois, S.3
  • 71
    • 26944437142 scopus 로고    scopus 로고
    • Phospho-Caveolin-1 mediates integrin-regulated membrane domain internalization
    • del Pozo MA, Balasubramanian N, Alderson NB, et al. Phospho-Caveolin-1 mediates integrin-regulated membrane domain internalization. Nat Cell Biol 2005; 7(9): 901-8.
    • (2005) Nat Cell Biol , vol.7 , Issue.9 , pp. 901-908
    • del Pozo, M.A.1    Balasubramanian, N.2    Alderson, N.B.3
  • 72
    • 34247562835 scopus 로고    scopus 로고
    • Rac, membrane heterogeneity, Caveolin and regulation of growth by integrins
    • Del Pozo MA, Schwartz MA. Rac, membrane heterogeneity, Caveolin and regulation of growth by integrins. Trends Cell Biol 2007; 17(5): 246-50.
    • (2007) Trends Cell Biol , vol.17 , Issue.5 , pp. 246-250
    • Del Pozo, M.A.1    Schwartz, M.A.2
  • 73
    • 33645703580 scopus 로고    scopus 로고
    • Epithelial growth factor-induced phosphorylation of Caveolin 1 at tyrosine 14 stimulates caveolae formation in epithelial cells
    • Orlichenko L, Huang B, Krueger E, McNiven MA. Epithelial growth factor-induced phosphorylation of Caveolin 1 at tyrosine 14 stimulates caveolae formation in epithelial cells. J Biol Chem 2006; 281(8): 4570-9.
    • (2006) J Biol Chem , vol.281 , Issue.8 , pp. 4570-4579
    • Orlichenko, L.1    Huang, B.2    Krueger, E.3    McNiven, M.A.4
  • 74
    • 34447576938 scopus 로고    scopus 로고
    • Caveolin-1alpha and -1beta perform nonredundant roles in early vertebrate development
    • Fang PK, Solomon KR, Zhuang L, et al. Caveolin-1alpha and -1beta perform nonredundant roles in early vertebrate development. Am J Pathol 2006; 169(6): 2209-22.
    • (2006) Am J Pathol , vol.169 , Issue.6 , pp. 2209-2222
    • Fang, P.K.1    Solomon, K.R.2    Zhuang, L.3
  • 75
    • 0035158471 scopus 로고    scopus 로고
    • Caveolin-1 expression negatively regulates cell cycle progression by inducing G(0)/G(1) arrest via a p53/p21(WAF1/Cip1)-dependent mechanism
    • Galbiati F, Volonte D, Liu J, et al. Caveolin-1 expression negatively regulates cell cycle progression by inducing G(0)/G(1) arrest via a p53/p21(WAF1/Cip1)-dependent mechanism. Mol Biol Cell 2001; 12(8): 2229-44.
    • (2001) Mol Biol Cell , vol.12 , Issue.8 , pp. 2229-2244
    • Galbiati, F.1    Volonte, D.2    Liu, J.3
  • 76
    • 0036323674 scopus 로고    scopus 로고
    • Expression of Caveolin-1 induces premature cellular senescence in primary cultures of murine fibroblasts
    • Volonte D, Zhang K, Lisanti MP, Galbiati F. Expression of Caveolin-1 induces premature cellular senescence in primary cultures of murine fibroblasts. Mol Biol Cell 2002; 13(7): 2502-17.
    • (2002) Mol Biol Cell , vol.13 , Issue.7 , pp. 2502-2517
    • Volonte, D.1    Zhang, K.2    Lisanti, M.P.3    Galbiati, F.4
  • 77
    • 33845345975 scopus 로고    scopus 로고
    • Oxidative stress induces premature senescence by stimulating Caveolin-1 gene transcription through p38 mitogen-activated protein kinase/Sp1-mediated activation of two GC-rich promoter elements
    • Dasari A, Bartholomew JN, Volonte D, Galbiati F. Oxidative stress induces premature senescence by stimulating Caveolin-1 gene transcription through p38 mitogen-activated protein kinase/Sp1-mediated activation of two GC-rich promoter elements. Cancer Res 2006; 66(22): 10805-14.
    • (2006) Cancer Res , vol.66 , Issue.22 , pp. 10805-10814
    • Dasari, A.1    Bartholomew, J.N.2    Volonte, D.3    Galbiati, F.4
  • 78
    • 0032538790 scopus 로고    scopus 로고
    • Targeted downregulation of Caveolin-1 is sufficient to drive cell transformation and hyperactivate the p42/44 MAP kinase cascade
    • Galbiati F, Volonte D, Engelman JA, et al. Targeted downregulation of Caveolin-1 is sufficient to drive cell transformation and hyperactivate the p42/44 MAP kinase cascade. EMBO J 1998; 17(22): 6633-48.
    • (1998) EMBO J , vol.17 , Issue.22 , pp. 6633-6648
    • Galbiati, F.1    Volonte, D.2    Engelman, J.A.3
  • 79
    • 0033018603 scopus 로고    scopus 로고
    • Visualization of Caveolin-1, a caveolar marker protein, in living cells using green fluorescent protein (GFP) chimeras. The subcellular distribution of Caveolin-1 is modulated by cell-cell contact
    • Volonte D, Galbiati F, Lisanti MP. Visualization of Caveolin-1, a caveolar marker protein, in living cells using green fluorescent protein (GFP) chimeras. The subcellular distribution of Caveolin-1 is modulated by cell-cell contact. FEBS Lett 1999; 445(2-3): 431-9.
    • (1999) FEBS Lett , vol.445 , Issue.2-3 , pp. 431-439
    • Volonte, D.1    Galbiati, F.2    Lisanti, M.P.3
  • 80
    • 0345736990 scopus 로고    scopus 로고
    • Downregulation of Caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of beta-catenin, and enhanced tumor cell invasion
    • Lu Z, Ghosh S, Wang Z, Hunter T. Downregulation of Caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of beta-catenin, and enhanced tumor cell invasion. Cancer Cell 2003; 4(6): 499-515.
    • (2003) Cancer Cell , vol.4 , Issue.6 , pp. 499-515
    • Lu, Z.1    Ghosh, S.2    Wang, Z.3    Hunter, T.4
  • 81
    • 33744529908 scopus 로고    scopus 로고
    • Caveolin-1 controls cell proliferation and cell death by suppressing expression of the inhibitor of apoptosis protein survivin
    • Torres VA, Tapia JC, Rodriguez DA, et al. Caveolin-1 controls cell proliferation and cell death by suppressing expression of the inhibitor of apoptosis protein survivin. J Cell Sci 2006; 119(Pt 9): 1812-23.
    • (2006) J Cell Sci , vol.119 , Issue.Pt 9 , pp. 1812-1823
    • Torres, V.A.1    Tapia, J.C.2    Rodriguez, D.A.3
  • 82
    • 65249138239 scopus 로고    scopus 로고
    • Caveolin-1- mediated suppression of cyclooxygenase-2 via a betacatenin- Tcf/Lef-dependent transcriptional mechanism reduced prostaglandin E2 production and survivin expression
    • Rodriguez DA, Tapia JC, Fernandez JG, et al. Caveolin-1- mediated suppression of cyclooxygenase-2 via a betacatenin- Tcf/Lef-dependent transcriptional mechanism reduced prostaglandin E2 production and survivin expression. Mol Biol Cell 2009; 20(8): 2297-310.
    • (2009) Mol Biol Cell , vol.20 , Issue.8 , pp. 2297-2310
    • Rodriguez, D.A.1    Tapia, J.C.2    Fernandez, J.G.3
  • 83
    • 0034647728 scopus 로고    scopus 로고
    • The cyclin D1 gene is transcriptionally repressed by Caveolin-1
    • Hulit J, Bash T, Fu M, et al. The cyclin D1 gene is transcriptionally repressed by Caveolin-1. J Biol Chem 2000; 275(28): 21203-9.
    • (2000) J Biol Chem , vol.275 , Issue.28 , pp. 21203-21209
    • Hulit, J.1    Bash, T.2    Fu, M.3
  • 84
    • 79960338573 scopus 로고    scopus 로고
    • Docosahexaenoic acid (DHA) sensitizes brain tumor cells to etoposide-induced apoptosis
    • Wang F, Bhat K, Doucette M, et al. Docosahexaenoic acid (DHA) sensitizes brain tumor cells to etoposide-induced apoptosis. Curr Mol Med 2011; 11(6): 503-11.
    • (2011) Curr Mol Med , vol.11 , Issue.6 , pp. 503-511
    • Wang, F.1    Bhat, K.2    Doucette, M.3
  • 85
    • 29244473885 scopus 로고    scopus 로고
    • Loss of Caveolin-1 causes the hyper-proliferation of intestinal crypt stem cells, with increased sensitivity to whole body gamma-radiation
    • Li J, Hassan GS, Williams TM, et al. Loss of Caveolin-1 causes the hyper-proliferation of intestinal crypt stem cells, with increased sensitivity to whole body gamma-radiation. Cell Cycle 2005; 4(12): 1817-25.
    • (2005) Cell Cycle , vol.4 , Issue.12 , pp. 1817-1825
    • Li, J.1    Hassan, G.S.2    Williams, T.M.3
  • 86
    • 29244451080 scopus 로고    scopus 로고
    • Caveolin-1-deficient mice have an increased mammary stem cell population with upregulation of Wnt/betacatenin signaling
    • Sotgia F, Williams TM, Cohen AW, Minetti C, Pestell RG, Lisanti MP. Caveolin-1-deficient mice have an increased mammary stem cell population with upregulation of Wnt/betacatenin signaling. Cell Cycle 2005; 4(12): 1808-16.
    • (2005) Cell Cycle , vol.4 , Issue.12 , pp. 1808-1816
    • Sotgia, F.1    Williams, T.M.2    Cohen, A.W.3    Minetti, C.4    Pestell, R.G.5    Lisanti, M.P.6
  • 87
    • 2142647335 scopus 로고    scopus 로고
    • The biology of caveolae: Lessons from Caveolin knockout mice and implications for human disease
    • Hnasko R, Lisanti MP. The biology of caveolae: lessons from Caveolin knockout mice and implications for human disease. Mol Interv 2003; 3(8): 445-64.
    • (2003) Mol Interv , vol.3 , Issue.8 , pp. 445-464
    • Hnasko, R.1    Lisanti, M.P.2
  • 88
    • 29144505268 scopus 로고    scopus 로고
    • Getting rid of Caveolins: Phenotypes of Caveolin-deficient animals
    • Le Lay S, Kurzchalia TV. Getting rid of Caveolins: phenotypes of Caveolin-deficient animals. Biochim Biophys Acta 2005; 1746(3): 322-33.
    • (2005) Biochim Biophys Acta , vol.1746 , Issue.3 , pp. 322-333
    • Le Lay, S.1    Kurzchalia, T.V.2
  • 89
    • 55949085790 scopus 로고    scopus 로고
    • Restoration of Caveolin-1 expression suppresses growth and metastasis of head and neck squamous cell carcinoma
    • Zhang H, Su L, Muller S, et al. Restoration of Caveolin-1 expression suppresses growth and metastasis of head and neck squamous cell carcinoma. Br J Cancer 2008; 99(10): 1684-94.
    • (2008) Br J Cancer , vol.99 , Issue.10 , pp. 1684-1694
    • Zhang, H.1    Su, L.2    Muller, S.3
  • 90
    • 34848844374 scopus 로고    scopus 로고
    • Caveolin-1 inhibits the growth of human laryngeal squamous cell carcinoma and down regulates EGFR-MAPKs signaling pathway
    • Gu D, Li H, Wang Z, Chen Q, Jiang J, Zhu H. Caveolin-1 inhibits the growth of human laryngeal squamous cell carcinoma and down regulates EGFR-MAPKs signaling pathway. Laryngoscope 2007; 117(10): 1782-9.
    • (2007) Laryngoscope , vol.117 , Issue.10 , pp. 1782-1789
    • Gu, D.1    Li, H.2    Wang, Z.3    Chen, Q.4    Jiang, J.5    Zhu, H.6
  • 91
    • 33748421657 scopus 로고    scopus 로고
    • Role of Caveolin-1 in p42/p44 MAP kinase activation and proliferation of human airway smooth muscle
    • Gosens R, Stelmack GL, Dueck G, et al. Role of Caveolin-1 in p42/p44 MAP kinase activation and proliferation of human airway smooth muscle. Am J Physiol Lung Cell Mol Physiol 2006; 291(3): L523-34.
    • (2006) Am J Physiol Lung Cell Mol Physiol , vol.291 , Issue.3
    • Gosens, R.1    Stelmack, G.L.2    Dueck, G.3
  • 92
    • 0034653608 scopus 로고    scopus 로고
    • The PI3K-PDK1 connection: More than just a road to PKB
    • Vanhaesebroeck B, Alessi DR. The PI3K-PDK1 connection: more than just a road to PKB. Biochem J 2000; 346(Pt 3): 561-76.
    • (2000) Biochem J , vol.346 , Issue.Pt 3 , pp. 561-576
    • Vanhaesebroeck, B.1    Alessi, D.R.2
  • 93
    • 2342618936 scopus 로고    scopus 로고
    • Multiple roles of the PI3K/PKB (Akt) pathway in cell cycle progression
    • Liang J, Slingerland JM. Multiple roles of the PI3K/PKB (Akt) pathway in cell cycle progression. Cell Cycle 2003; 2(4): 339-45.
    • (2003) Cell Cycle , vol.2 , Issue.4 , pp. 339-345
    • Liang, J.1    Slingerland, J.M.2
  • 94
    • 33644513730 scopus 로고    scopus 로고
    • Beyond PTEN mutations: The PI3K pathway as an integrator of multiple inputs during tumorigenesis
    • Cully M, You H, Levine AJ, Mak TW. Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis. Nat Rev Cancer 2006; 6(3): 184-92.
    • (2006) Nat Rev Cancer , vol.6 , Issue.3 , pp. 184-192
    • Cully, M.1    You, H.2    Levine, A.J.3    Mak, T.W.4
  • 96
    • 0034141535 scopus 로고    scopus 로고
    • Phosphatidylinositide 3-kinase localizes to cytoplasmic lipid bodies in human polymorphonuclear leukocytes and other myeloid-derived cells
    • Yu W, Cassara J, Weller PF. Phosphatidylinositide 3-kinase localizes to cytoplasmic lipid bodies in human polymorphonuclear leukocytes and other myeloid-derived cells. Blood 2000; 95(3): 1078-85.
    • (2000) Blood , vol.95 , Issue.3 , pp. 1078-1085
    • Yu, W.1    Cassara, J.2    Weller, P.F.3
  • 97
    • 77953694572 scopus 로고    scopus 로고
    • Caveolin-1 gene silencing promotes the activation of PI3K/AKT dependent on Eralpha36 and the transformation of MCF10ACE
    • Feng S, Wang Y, Wang X, et al. Caveolin-1 gene silencing promotes the activation of PI3K/AKT dependent on Eralpha36 and the transformation of MCF10ACE. Sci China Life Sci 2010; 53(5): 598-605.
    • (2010) Sci China Life Sci , vol.53 , Issue.5 , pp. 598-605
    • Feng, S.1    Wang, Y.2    Wang, X.3
  • 98
    • 77953188523 scopus 로고    scopus 로고
    • Pathologic Caveolin-1 regulation of PTEN in idiopathic pulmonary fibrosis
    • Xia H, Khalil W, Kahm J, Jessurun J, Kleidon J, Henke CA. Pathologic Caveolin-1 regulation of PTEN in idiopathic pulmonary fibrosis. Am J Pathol 2010; 176(6): 2626-37.
    • (2010) Am J Pathol , vol.176 , Issue.6 , pp. 2626-2637
    • Xia, H.1    Khalil, W.2    Kahm, J.3    Jessurun, J.4    Kleidon, J.5    Henke, C.A.6
  • 100
    • 0037379438 scopus 로고    scopus 로고
    • Caveolin-induced activation of the phosphatidylinositol 3-kinase/Akt pathway increases arsenite cytotoxicity
    • Shack S, Wang XT, Kokkonen GC, Gorospe M, Longo DL, Holbrook NJ. Caveolin-induced activation of the phosphatidylinositol 3-kinase/Akt pathway increases arsenite cytotoxicity. Mol Cell Biol 2003; 23(7): 2407-14.
    • (2003) Mol Cell Biol , vol.23 , Issue.7 , pp. 2407-2414
    • Shack, S.1    Wang, X.T.2    Kokkonen, G.C.3    Gorospe, M.4    Longo, D.L.5    Holbrook, N.J.6
  • 101
    • 0033965898 scopus 로고    scopus 로고
    • Caveolin 1-mediated regulation of receptor tyrosine kinase-associated phosphatidylinositol 3-kinase activity by ceramide
    • Zundel W, Swiersz LM, Giaccia A. Caveolin 1-mediated regulation of receptor tyrosine kinase-associated phosphatidylinositol 3-kinase activity by ceramide. Mol Cell Biol 2000; 20(5): 1507-14.
    • (2000) Mol Cell Biol , vol.20 , Issue.5 , pp. 1507-1514
    • Zundel, W.1    Swiersz, L.M.2    Giaccia, A.3
  • 102
    • 35649009855 scopus 로고    scopus 로고
    • E-cadherin is required for Caveolin-1-mediated down-regulation of the inhibitor of apoptosis protein survivin via reduced betacatenin-Tcf/Lef-dependent transcription
    • Torres VA, Tapia JC, Rodriguez DA, et al. E-cadherin is required for Caveolin-1-mediated down-regulation of the inhibitor of apoptosis protein survivin via reduced betacatenin-Tcf/Lef-dependent transcription. Mol Cell Biol 2007; 27(21): 7703-17.
    • (2007) Mol Cell Biol , vol.27 , Issue.21 , pp. 7703-7717
    • Torres, V.A.1    Tapia, J.C.2    Rodriguez, D.A.3
  • 103
    • 80053999477 scopus 로고    scopus 로고
    • Xanthones from mangosteen extracts as natural chemopreventive agents: Potential anticancer drugs
    • Shan T, Ma Q, Guo K, et al. Xanthones from mangosteen extracts as natural chemopreventive agents: potential anticancer drugs. Curr Mol Med 2011; 11(8): 666-77.
    • (2011) Curr Mol Med , vol.11 , Issue.8 , pp. 666-677
    • Shan, T.1    Ma, Q.2    Guo, K.3
  • 104
    • 79551663808 scopus 로고    scopus 로고
    • The molecular machinery regulating apoptosis signal transduction and its implication in human physiology and pathophysiologies
    • Hellwig CT, Passante E, Rehm M. The molecular machinery regulating apoptosis signal transduction and its implication in human physiology and pathophysiologies. Curr Mol Med 2011; 11(1): 31-47.
    • (2011) Curr Mol Med , vol.11 , Issue.1 , pp. 31-47
    • Hellwig, C.T.1    Passante, E.2    Rehm, M.3
  • 105
    • 80053479183 scopus 로고    scopus 로고
    • Hyperoxia Therapy of Preproliferative Ischemic Retinopathy in a Mouse Model
    • Zhang W, Yokota H, Xu Z, et al. Hyperoxia Therapy of Preproliferative Ischemic Retinopathy in a Mouse Model. Invest Ophthalmol Vis Sci 2011; 52(9): 6384-95.
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , Issue.9 , pp. 6384-6395
    • Zhang, W.1    Yokota, H.2    Xu, Z.3
  • 106
    • 77958019874 scopus 로고    scopus 로고
    • Autophagy in cigarette smokeinduced chronic obstructive pulmonary disease
    • Ryter SW, Lee SJ, Choi AM. Autophagy in cigarette smokeinduced chronic obstructive pulmonary disease. Expert Rev Respir Med 2010; 4(5): 573-84.
    • (2010) Expert Rev Respir Med , vol.4 , Issue.5 , pp. 573-584
    • Ryter, S.W.1    Lee, S.J.2    Choi, A.M.3
  • 107
    • 79953657006 scopus 로고    scopus 로고
    • Deadly triplex: Smoke, autophagy and apoptosis
    • Ryter SW, Lam HC, Chen ZH, Choi AM. Deadly triplex: smoke, autophagy and apoptosis. Autophagy 2011; 7(4): 436-7.
    • (2011) Autophagy , vol.7 , Issue.4 , pp. 436-437
    • Ryter, S.W.1    Lam, H.C.2    Chen, Z.H.3    Choi, A.M.4
  • 108
    • 0036024019 scopus 로고    scopus 로고
    • Induction of acetylcholinesterase expression during apoptosis in various cell types
    • Zhang XJ, Yang L, Zhao Q, et al. Induction of acetylcholinesterase expression during apoptosis in various cell types. Cell Death Differ 2002; 9(8): 790-800.
    • (2002) Cell Death Differ , vol.9 , Issue.8 , pp. 790-800
    • Zhang, X.J.1    Yang, L.2    Zhao, Q.3
  • 109
    • 4043104785 scopus 로고    scopus 로고
    • Overexpression of acetylcholinesterase inhibited cell proliferation and promoted apoptosis in NRK cells
    • Jin QH, He HY, Shi YF, Lu H, Zhang XJ. Overexpression of acetylcholinesterase inhibited cell proliferation and promoted apoptosis in NRK cells. Acta Pharmacol Sin 2004; 25(8): 1013-21.
    • (2004) Acta Pharmacol Sin , vol.25 , Issue.8 , pp. 1013-1021
    • Jin, Q.H.1    He, H.Y.2    Shi, Y.F.3    Lu, H.4    Zhang, X.J.5
  • 110
    • 41849089728 scopus 로고    scopus 로고
    • Interactions of acetylcholinesterase with Caveolin-1 and subsequently with cytochrome c are required for apoptosome formation
    • Park SE, Jeong SH, Yee SB, et al. Interactions of acetylcholinesterase with Caveolin-1 and subsequently with cytochrome c are required for apoptosome formation. Carcinogenesis 2008; 29(4): 729-37.
    • (2008) Carcinogenesis , vol.29 , Issue.4 , pp. 729-737
    • Park, S.E.1    Jeong, S.H.2    Yee, S.B.3
  • 112
    • 0141794280 scopus 로고    scopus 로고
    • Cellular apoptosis is associated with increased Caveolin-1 expression in macrophages
    • Gargalovic P, Dory L. Cellular apoptosis is associated with increased Caveolin-1 expression in macrophages. J Lipid Res 2003; 44(9): 1622-32.
    • (2003) J Lipid Res , vol.44 , Issue.9 , pp. 1622-1632
    • Gargalovic, P.1    Dory, L.2
  • 114
    • 0035943423 scopus 로고    scopus 로고
    • Emerging themes in lipid rafts and caveolae
    • Galbiati F, Razani B, Lisanti MP. Emerging themes in lipid rafts and caveolae. Cell 2001; 106(4): 403-11.
    • (2001) Cell , vol.106 , Issue.4 , pp. 403-411
    • Galbiati, F.1    Razani, B.2    Lisanti, M.P.3
  • 115
    • 38549112056 scopus 로고    scopus 로고
    • Caveolin-1 down-regulation inhibits insulin-like growth factor- I receptor signal transduction in H9C2 rat cardiomyoblasts
    • Salani B, Briatore L, Garibaldi S, Cordera R, Maggi D. Caveolin-1 down-regulation inhibits insulin-like growth factor- I receptor signal transduction in H9C2 rat cardiomyoblasts. Endocrinology 2008; 149(2): 461-5.
    • (2008) Endocrinology , vol.149 , Issue.2 , pp. 461-465
    • Salani, B.1    Briatore, L.2    Garibaldi, S.3    Cordera, R.4    Maggi, D.5
  • 116
    • 26844557817 scopus 로고    scopus 로고
    • Insulin and IGF-I phosphorylate eNOS in HUVECs by a Caveolin-1 dependent mechanism
    • Repetto S, Salani B, Maggi D, Cordera R. Insulin and IGF-I phosphorylate eNOS in HUVECs by a Caveolin-1 dependent mechanism. Biochem Biophys Res Commun 2005; 337(3): 849-52.
    • (2005) Biochem Biophys Res Commun , vol.337 , Issue.3 , pp. 849-852
    • Repetto, S.1    Salani, B.2    Maggi, D.3    Cordera, R.4
  • 117
    • 0345491598 scopus 로고    scopus 로고
    • Caveolin-1 maintains activated Akt in prostate cancer cells through scaffolding domain binding site interactions with and inhibition of serine/threonine protein phosphatases PP1 and PP2A
    • Li L, Ren CH, Tahir SA, Ren C, Thompson TC. Caveolin-1 maintains activated Akt in prostate cancer cells through scaffolding domain binding site interactions with and inhibition of serine/threonine protein phosphatases PP1 and PP2A. Mol Cell Biol 2003; 23(24): 9389-404.
    • (2003) Mol Cell Biol , vol.23 , Issue.24 , pp. 9389-9404
    • Li, L.1    Ren, C.H.2    Tahir, S.A.3    Ren, C.4    Thompson, T.C.5
  • 118
    • 0034612591 scopus 로고    scopus 로고
    • Caveolin-1 is regulated by c-myc and suppresses c-myc-induced apoptosis
    • Timme TL, Goltsov A, Tahir S, et al. Caveolin-1 is regulated by c-myc and suppresses c-myc-induced apoptosis. Oncogene 2000; 19(29): 3256-65.
    • (2000) Oncogene , vol.19 , Issue.29 , pp. 3256-3265
    • Timme, T.L.1    Goltsov, A.2    Tahir, S.3
  • 119
    • 21644452110 scopus 로고    scopus 로고
    • Caveolin-1 promotes tumor progression in an autochthonous mouse model of prostate cancer: Genetic ablation of Cav-1 delays advanced prostate tumor development in tramp mice
    • Williams TM, Hassan GS, Li J, et al. Caveolin-1 promotes tumor progression in an autochthonous mouse model of prostate cancer: genetic ablation of Cav-1 delays advanced prostate tumor development in tramp mice. J Biol Chem 2005; 280(26): 25134-45.
    • (2005) J Biol Chem , vol.280 , Issue.26 , pp. 25134-25445
    • Williams, T.M.1    Hassan, G.S.2    Li, J.3
  • 120
    • 36348964327 scopus 로고    scopus 로고
    • Identification of a novel inhibitor of differentiation-1 (ID-1) binding partner, Caveolin- 1, and its role in epithelial-mesenchymal transition and resistance to apoptosis in prostate cancer cells
    • Zhang X, Ling MT, Wang Q, et al. Identification of a novel inhibitor of differentiation-1 (ID-1) binding partner, Caveolin- 1, and its role in epithelial-mesenchymal transition and resistance to apoptosis in prostate cancer cells. J Biol Chem 2007; 282(46): 33284-94.
    • (2007) J Biol Chem , vol.282 , Issue.46 , pp. 33284-33294
    • Zhang, X.1    Ling, M.T.2    Wang, Q.3
  • 121
    • 40449119641 scopus 로고    scopus 로고
    • Caveolin-1 expression is essential for N-methyl-D-aspartate receptormediated Src and extracellular signal-regulated kinase 1/2 activation and protection of primary neurons from ischemic cell death
    • Head BP, Patel HH, Tsutsumi YM, et al. Caveolin-1 expression is essential for N-methyl-D-aspartate receptormediated Src and extracellular signal-regulated kinase 1/2 activation and protection of primary neurons from ischemic cell death. FASEB J 2008; 22(3): 828-40.
    • (2008) FASEB J , vol.22 , Issue.3 , pp. 828-840
    • Head, B.P.1    Patel, H.H.2    Tsutsumi, Y.M.3
  • 122
    • 77449155377 scopus 로고    scopus 로고
    • Overexpression of Caveolin-1 in lymphoblastoid TK6 cells enhances proliferation after irradiation with clinically relevant doses
    • Barzan D, Maier P, Zeller WJ, Wenz F, Herskind C. Overexpression of Caveolin-1 in lymphoblastoid TK6 cells enhances proliferation after irradiation with clinically relevant doses. Strahlenther Onkol 2010; 186(2): 99-106.
    • (2010) Strahlenther Onkol , vol.186 , Issue.2 , pp. 99-106
    • Barzan, D.1    Maier, P.2    Zeller, W.J.3    Wenz, F.4    Herskind, C.5
  • 123
    • 35348965193 scopus 로고    scopus 로고
    • Human pancreatic tumor cells are sensitized to ionizing radiation by knockdown of Caveolin-1
    • Cordes N, Frick S, Brunner TB, et al. Human pancreatic tumor cells are sensitized to ionizing radiation by knockdown of Caveolin-1. Oncogene 2007; 26(48): 6851-62.
    • (2007) Oncogene , vol.26 , Issue.48 , pp. 6851-6862
    • Cordes, N.1    Frick, S.2    Brunner, T.B.3
  • 124
    • 70350514910 scopus 로고    scopus 로고
    • Nitric oxide regulates lung carcinoma cell anoikis through inhibition of ubiquitin-proteasomal degradation of Caveolin-1
    • Chanvorachote P, Nimmannit U, Lu Y, Talbott S, Jiang BH, Rojanasakul Y. Nitric oxide regulates lung carcinoma cell anoikis through inhibition of ubiquitin-proteasomal degradation of Caveolin-1. J Biol Chem 2009; 284(41): 28476-84.
    • (2009) J Biol Chem , vol.284 , Issue.41 , pp. 28476-28484
    • Chanvorachote, P.1    Nimmannit, U.2    Lu, Y.3    Talbott, S.4    Jiang, B.H.5    Rojanasakul, Y.6
  • 125
    • 84866286281 scopus 로고    scopus 로고
    • Caveolin-1 is related to invasion, survival, and poor prognosis in hepatocellular cancer
    • Tang Y, Zeng X, He F, Liao Y, Qian N, Toi M. Caveolin-1 is related to invasion, survival, and poor prognosis in hepatocellular cancer. Med Oncol 2012; 29(2): 977-84.
    • (2012) Med Oncol , vol.29 , Issue.2 , pp. 977-984
    • Tang, Y.1    Zeng, X.2    He, F.3    Liao, Y.4    Qian, N.5    Toi, M.6
  • 126
    • 70349661779 scopus 로고    scopus 로고
    • Apoptosis of lens epithelial cells induced by high concentration of glucose is associated with a decrease in Caveolin-1 levels
    • Zhang Z, Yao K, Jin C. Apoptosis of lens epithelial cells induced by high concentration of glucose is associated with a decrease in Caveolin-1 levels. Mol Vis 2009; 15: 2008-17.
    • (2009) Mol Vis , vol.15 , pp. 2008-2017
    • Zhang, Z.1    Yao, K.2    Jin, C.3
  • 127
    • 53149114868 scopus 로고    scopus 로고
    • Interaction of Caveolin-1, nitric oxide, and nitric oxide synthases in hypoxic human SK-N-MC neuroblastoma cells
    • Shen J, Lee W, Li Y, et al. Interaction of Caveolin-1, nitric oxide, and nitric oxide synthases in hypoxic human SK-N-MC neuroblastoma cells. J Neurochem 2008; 107(2): 478-87.
    • (2008) J Neurochem , vol.107 , Issue.2 , pp. 478-487
    • Shen, J.1    Lee, W.2    Li, Y.3
  • 128
    • 68049101140 scopus 로고    scopus 로고
    • Role of Caveolin-1 in thyroid phenotype, cell homeostasis, and hormone synthesis: In vivo study of Caveolin-1 knockout mice
    • Senou M, Costa MJ, Massart C, et al. Role of Caveolin-1 in thyroid phenotype, cell homeostasis, and hormone synthesis: in vivo study of Caveolin-1 knockout mice. Am J Physiol Endocrinol Metab 2009; 297(2): E438-51.
    • (2009) Am J Physiol Endocrinol Metab , vol.297 , Issue.2
    • Senou, M.1    Costa, M.J.2    Massart, C.3
  • 130
    • 67650656774 scopus 로고    scopus 로고
    • Reversal of ABC drug transporter-mediated multidrug resistance in cancer cells: Evaluation of current strategies
    • Wu CP, Calcagno AM, Ambudkar SV. Reversal of ABC drug transporter-mediated multidrug resistance in cancer cells: evaluation of current strategies. Curr Mol Pharmacol 2008; 1(2): 93-105.
    • (2008) Curr Mol Pharmacol , vol.1 , Issue.2 , pp. 93-105
    • Wu, C.P.1    Calcagno, A.M.2    Ambudkar, S.V.3
  • 131
    • 28444443688 scopus 로고    scopus 로고
    • Expression of Caveolin-1 in pleomorphic carcinoma of the lung is correlated with a poor prognosis
    • Moon KC, Lee GK, Yoo SH, et al. Expression of Caveolin-1 in pleomorphic carcinoma of the lung is correlated with a poor prognosis. Anticancer Res 2005; 25(6C): 4631-7.
    • (2005) Anticancer Res , vol.25 , Issue.6 C , pp. 4631-4637
    • Moon, K.C.1    Lee, G.K.2    Yoo, S.H.3
  • 132
    • 18744386654 scopus 로고    scopus 로고
    • Impact of Caveolin-1 expression on prognosis of pancreatic ductal adenocarcinoma
    • Suzuoki M, Miyamoto M, Kato K, et al. Impact of Caveolin-1 expression on prognosis of pancreatic ductal adenocarcinoma. Br J Cancer 2002; 87(10): 1140-4.
    • (2002) Br J Cancer , vol.87 , Issue.10 , pp. 1140-1144
    • Suzuoki, M.1    Miyamoto, M.2    Kato, K.3
  • 133
    • 0348013440 scopus 로고    scopus 로고
    • Caveolin-1 overexpression predicts poor disease-free survival of patients with clinically confined renal cell carcinoma
    • Campbell L, Gumbleton M, Griffiths DF. Caveolin-1 overexpression predicts poor disease-free survival of patients with clinically confined renal cell carcinoma. Br J Cancer 2003; 89(10): 1909-13.
    • (2003) Br J Cancer , vol.89 , Issue.10 , pp. 1909-1913
    • Campbell, L.1    Gumbleton, M.2    Griffiths, D.F.3
  • 134
    • 69749115434 scopus 로고    scopus 로고
    • Role of Caveolin 1, E-cadherin, Enolase 2 and PKCalpha on resistance to methotrexate in human HT29 colon cancer cells
    • Selga E, Morales C, Noe V, Peinado MA, Ciudad CJ. Role of Caveolin 1, E-cadherin, Enolase 2 and PKCalpha on resistance to methotrexate in human HT29 colon cancer cells. BMC Med Genomics 2008; 1: 35.
    • (2008) BMC Med Genomics , vol.1 , pp. 35
    • Selga, E.1    Morales, C.2    Noe, V.3    Peinado, M.A.4    Ciudad, C.J.5
  • 135
    • 13644253850 scopus 로고    scopus 로고
    • Role of Caveolin-1 in etoposide resistance development in A549 lung cancer cells
    • Belanger MM, Gaudreau M, Roussel E, Couet J. Role of Caveolin-1 in etoposide resistance development in A549 lung cancer cells. Cancer Biol Ther 2004; 3(10): 954-9.
    • (2004) Cancer Biol Ther , vol.3 , Issue.10 , pp. 954-959
    • Belanger, M.M.1    Gaudreau, M.2    Roussel, E.3    Couet, J.4
  • 136
    • 34249281326 scopus 로고    scopus 로고
    • Bleomycin induces Caveolin-1 and -2 expression in epithelial lung cancer A549 cells
    • Linge A, Morishima N, Kasper M, Barth K. Bleomycin induces Caveolin-1 and -2 expression in epithelial lung cancer A549 cells. Anticancer Res 2007; 27(3A): 1343-51.
    • (2007) Anticancer Res , vol.27 , Issue.3 A , pp. 1343-1351
    • Linge, A.1    Morishima, N.2    Kasper, M.3    Barth, K.4
  • 137
    • 73549092273 scopus 로고    scopus 로고
    • Caveolin-1 promotes resistance to chemotherapy-induced apoptosis in Ewing's sarcoma cells by modulating PKCalpha phosphorylation
    • Tirado OM, MacCarthy CM, Fatima N, Villar J, Mateo-Lozano S, Notario V. Caveolin-1 promotes resistance to chemotherapy-induced apoptosis in Ewing's sarcoma cells by modulating PKCalpha phosphorylation. Int J Cancer 2010; 126(2): 426-36.
    • (2010) Int J Cancer , vol.126 , Issue.2 , pp. 426-436
    • Tirado, O.M.1    Maccarthy, C.M.2    Fatima, N.3    Villar, J.4    Mateo-Lozano, S.5    Notario, V.6
  • 138
    • 0032831879 scopus 로고    scopus 로고
    • Caveolin-1, a metastasis-related gene that promotes cell survival in prostate cancer
    • Thompson TC, Timme TL, Li L, Goltsov A. Caveolin-1, a metastasis-related gene that promotes cell survival in prostate cancer. Apoptosis 1999; 4(4): 233-7.
    • (1999) Apoptosis , vol.4 , Issue.4 , pp. 233-237
    • Thompson, T.C.1    Timme, T.L.2    Li, L.3    Goltsov, A.4
  • 139
    • 0031665843 scopus 로고    scopus 로고
    • Suppression of Caveolin expression induces androgen sensitivity in metastatic androgen-insensitive mouse prostate cancer cells
    • Nasu Y, Timme TL, Yang G, et al. Suppression of Caveolin expression induces androgen sensitivity in metastatic androgen-insensitive mouse prostate cancer cells. Nat Med 1998; 4(9): 1062-4.
    • (1998) Nat Med , vol.4 , Issue.9 , pp. 1062-1064
    • Nasu, Y.1    Timme, T.L.2    Yang, G.3
  • 140
    • 70349462592 scopus 로고    scopus 로고
    • Caveolae contribute to the apoptosis resistance induced by the alpha(1A)-adrenoceptor in androgen-independent prostate cancer cells
    • Katsogiannou M, El Boustany C, Gackiere F, et al. Caveolae contribute to the apoptosis resistance induced by the alpha(1A)-adrenoceptor in androgen-independent prostate cancer cells. PLoS One 2009; 4(9): e7068.
    • (2009) PLoS One , vol.4 , Issue.9
    • Katsogiannou, M.1    El Boustany, C.2    Gackiere, F.3
  • 141
    • 78449241974 scopus 로고    scopus 로고
    • RNA interference-directed Caveolin-1 knockdown sensitizes SN12CPM6 cells to doxorubicin-induced apoptosis and reduces lung metastasis
    • Park J, Bae E, Lee C, et al. RNA interference-directed Caveolin-1 knockdown sensitizes SN12CPM6 cells to doxorubicin-induced apoptosis and reduces lung metastasis. Tumour Biol 2010; 31(6): 643-50.
    • (2010) Tumour Biol , vol.31 , Issue.6 , pp. 643-650
    • Park, J.1    Bae, E.2    Lee, C.3
  • 142
    • 78751631885 scopus 로고    scopus 로고
    • Knockdown of Caveolin-1 decreases activity of breast cancer resistance protein (BCRP/ABCG2) and increases chemotherapeutic sensitivity
    • Herzog M, Storch CH, Gut P, et al. Knockdown of Caveolin-1 decreases activity of breast cancer resistance protein (BCRP/ABCG2) and increases chemotherapeutic sensitivity. Naunyn Schmiedebergs Arch Pharmacol 2010; 383(1): 1-11.
    • (2010) Naunyn Schmiedebergs Arch Pharmacol , vol.383 , Issue.1 , pp. 1-11
    • Herzog, M.1    Storch, C.H.2    Gut, P.3
  • 143
    • 0033963650 scopus 로고    scopus 로고
    • P-glycoprotein is localized in caveolae in resistant cells and in brain capillaries
    • Demeule M, Jodoin J, Gingras D, Beliveau R. P-glycoprotein is localized in caveolae in resistant cells and in brain capillaries. FEBS Lett 2000; 466(2-3): 219-24.
    • (2000) FEBS Lett , vol.466 , Issue.2-3 , pp. 219-224
    • Demeule, M.1    Jodoin, J.2    Gingras, D.3    Beliveau, R.4
  • 144
    • 33947279373 scopus 로고    scopus 로고
    • Modulation of pglycoprotein function by Caveolin-1 phosphorylation
    • Barakat S, Demeule M, Pilorget A, et al. Modulation of pglycoprotein function by Caveolin-1 phosphorylation. J Neurochem 2007; 101(1): 1-8.
    • (2007) J Neurochem , vol.101 , Issue.1 , pp. 1-8
    • Barakat, S.1    Demeule, M.2    Pilorget, A.3
  • 145
    • 3042789876 scopus 로고    scopus 로고
    • Overexpression of Caveolin-1 induces alteration of multidrug resistance in Hs578T breast adenocarcinoma cells
    • Cai C, Chen J. Overexpression of Caveolin-1 induces alteration of multidrug resistance in Hs578T breast adenocarcinoma cells. Int J Cancer 2004; 111(4): 522-9.
    • (2004) Int J Cancer , vol.111 , Issue.4 , pp. 522-529
    • Cai, C.1    Chen, J.2
  • 146
    • 3242699515 scopus 로고    scopus 로고
    • Caveolin-1 gene is coordinately regulated with the multidrug resistance 1 gene in normal and leukemic bone marrow
    • Pang A, Au WY, Kwong YL. Caveolin-1 gene is coordinately regulated with the multidrug resistance 1 gene in normal and leukemic bone marrow. Leuk Res 2004; 28(9): 973-7.
    • (2004) Leuk Res , vol.28 , Issue.9 , pp. 973-977
    • Pang, A.1    Au, W.Y.2    Kwong, Y.L.3
  • 147
    • 2442614759 scopus 로고    scopus 로고
    • Caveolin-1 is downregulated in human lung carcinoma and acts as a candidate tumor suppressor gene
    • Belanger MM, Roussel E, Couet J. Caveolin-1 is downregulated in human lung carcinoma and acts as a candidate tumor suppressor gene. Chest 2004; 125(5 Suppl): 106S.
    • (2004) Chest , vol.125 , Issue.5 SUPPL.
    • Belanger, M.M.1    Roussel, E.2    Couet, J.3
  • 148
    • 34548843672 scopus 로고    scopus 로고
    • Localization of the human breast cancer resistance protein (BCRP/ABCG2) in lipid rafts/caveolae and modulation of its activity by cholesterol in vitro
    • Storch CH, Ehehalt R, Haefeli WE, Weiss J. Localization of the human breast cancer resistance protein (BCRP/ABCG2) in lipid rafts/caveolae and modulation of its activity by cholesterol in vitro. J Pharmacol Exp Ther 2007; 323(1): 257-64.
    • (2007) J Pharmacol Exp Ther , vol.323 , Issue.1 , pp. 257-264
    • Storch, C.H.1    Ehehalt, R.2    Haefeli, W.E.3    Weiss, J.4
  • 149
    • 0034997010 scopus 로고    scopus 로고
    • Caveolin-1 expression sensitizes fibroblastic and epithelial cells to apoptotic stimulation
    • Liu J, Lee P, Galbiati F, Kitsis RN, Lisanti MP. Caveolin-1 expression sensitizes fibroblastic and epithelial cells to apoptotic stimulation. Am J Physiol Cell Physiol 2001; 280(4): C823-35.
    • (2001) Am J Physiol Cell Physiol , vol.280 , Issue.4
    • Liu, J.1    Lee, P.2    Galbiati, F.3    Kitsis, R.N.4    Lisanti, M.P.5
  • 150
    • 72449172015 scopus 로고    scopus 로고
    • Deletion of Caveolin-1 protects hyperoxia-induced apoptosis via survivin-mediated pathways
    • Zhang M, Lin L, Lee SJ, et al. Deletion of Caveolin-1 protects hyperoxia-induced apoptosis via survivin-mediated pathways. Am J Physiol Lung Cell Mol Physiol 2009; 297(5): L945-53.
    • (2009) Am J Physiol Lung Cell Mol Physiol , vol.297 , Issue.5
    • Zhang, M.1    Lin, L.2    Lee, S.J.3


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