Autophagy opposes p53-mediated tumor barrier to facilitate tumorigenesis in a model of PALB2 -associated hereditary breast cancer

Cancer Discovery

Volumn 3, Issue 8, 2013, Pages 894-907

  Huo, Yanying ^a,b   Cai, Hong ^a,b   Teplova, Irina ^a   Bowman Colin, Christian ^d   Chen, Guanghua ^a   Price, Sandy ^a   Barnard, Nicola ^b   Ganesan, Shridar ^a,b   Karantza, Vassiliki ^a,b   White, Eileen ^a,c   Xia, Bing ^a,b  

^a RUTGERS CANCER INSTITUTE OF NEW JERSEY   (United States)

^b ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^c RUTGERS UNIVERSITY   (United States)

^d DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BECLIN 1; BETA GALACTOSIDASE; CRE RECOMBINASE; ESTROGEN RECEPTOR; LIPOCORTIN 5; MESSENGER RNA; OLAPARIB; PROGESTERONE RECEPTOR; PROTEIN P53; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NRF2;

ALLELE; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGY; BREAST ADENOCARCINOMA; BREAST CANCER; BREAST EPITHELIUM; CANCER INHIBITION; CARCINOGENESIS; CELL SURVIVAL; COMET ASSAY; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; EPITHELIAL MESENCHYMAL TRANSITION; EXON; FEMALE; FIBROBLAST; GENE DELETION; GENE INTERACTION; GENE MUTATION; GENOTYPE; HETEROZYGOSITY; HISTOLOGY; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; MOUSE; NECROSIS; NONHUMAN; OXIDATIVE STRESS; PHENOTYPE; SENESCENCE; TUMOR SUPPRESSOR GENE; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; BRCA1 PROTEIN; BRCA2 PROTEIN; CARCINOGENESIS; CELL AGING; DISEASE MODELS, ANIMAL; DNA DAMAGE; FEMALE; HETEROZYGOTE; HUMANS; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; MICE, KNOCKOUT; OXIDATIVE STRESS; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 84878129623     PISSN: 21598274     EISSN: 21598290     Source Type: Journal    
DOI: 10.1158/2159-8290.CD-13-0011     Document Type: Article

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