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Volumn 19, Issue Part A, 2014, Pages 58-68

Autophagy and mitophagy interplay in melanoma progression

Author keywords

Anticancer therapy; Autophagy; Cancer; Melanoma; Mitophagy; Signaling

Indexed keywords

MEMBRANE PROTEIN; PARKIN; PROTEIN BNIP3; PROTEIN FUNDC1; PROTEIN KINASE; PROTEIN NIX; PTEN INDUCED PUTATIVE PROTEIN KINASE 1; UNCLASSIFIED DRUG;

EID: 84911376088     PISSN: 15677249     EISSN: 18728278     Source Type: Journal    
DOI: 10.1016/j.mito.2014.07.003     Document Type: Article
Times cited : (39)

References (124)
  • 1
    • 84889100159 scopus 로고    scopus 로고
    • Loss of iron triggers PINK1/Parkin-independent mitophagy
    • Allen G.F., et al. Loss of iron triggers PINK1/Parkin-independent mitophagy. EMBO Rep. 2013, 14(12):1127-1135.
    • (2013) EMBO Rep. , vol.14 , Issue.12 , pp. 1127-1135
    • Allen, G.F.1
  • 2
    • 83755169511 scopus 로고    scopus 로고
    • Cancer. Autophagy in tumor immunity
    • Amaravadi R.K. Cancer. Autophagy in tumor immunity. Science 2011, 334(6062):1501-1502.
    • (2011) Science , vol.334 , Issue.6062 , pp. 1501-1502
    • Amaravadi, R.K.1
  • 3
    • 79954609211 scopus 로고    scopus 로고
    • Oncogenic B-RAF signaling in melanoma impairs the therapeutic advantage of autophagy inhibition
    • Armstrong J.L., et al. Oncogenic B-RAF signaling in melanoma impairs the therapeutic advantage of autophagy inhibition. Clin. Cancer Res. 2011, 17(8):2216-2226.
    • (2011) Clin. Cancer Res. , vol.17 , Issue.8 , pp. 2216-2226
    • Armstrong, J.L.1
  • 4
    • 84876341593 scopus 로고    scopus 로고
    • A KRAB/KAP1-miRNA cascade regulates erythropoiesis through stage-specific control of mitophagy
    • Barde I., et al. A KRAB/KAP1-miRNA cascade regulates erythropoiesis through stage-specific control of mitophagy. Science 2013, 340(6130):350-353.
    • (2013) Science , vol.340 , Issue.6130 , pp. 350-353
    • Barde, I.1
  • 5
    • 84899977406 scopus 로고    scopus 로고
    • Connexins modulate autophagosome biogenesis
    • Bejarano E., et al. Connexins modulate autophagosome biogenesis. Nat. Cell Biol. 2014, 16(5):401-414.
    • (2014) Nat. Cell Biol. , vol.16 , Issue.5 , pp. 401-414
    • Bejarano, E.1
  • 6
    • 84894326290 scopus 로고    scopus 로고
    • Mitochondrial ER contacts are crucial for mitophagy in yeast
    • Bockler S., Westermann B. Mitochondrial ER contacts are crucial for mitophagy in yeast. Dev. Cell 2014, 28(4):450-458.
    • (2014) Dev. Cell , vol.28 , Issue.4 , pp. 450-458
    • Bockler, S.1    Westermann, B.2
  • 7
    • 84864389175 scopus 로고    scopus 로고
    • Autophagy Suppresses RIP Kinase-Dependent Necrosis Enabling Survival to mTOR Inhibition
    • Bray K., et al. Autophagy Suppresses RIP Kinase-Dependent Necrosis Enabling Survival to mTOR Inhibition. PLoS One 2012, 7(7):e41831.
    • (2012) PLoS One , vol.7 , Issue.7 , pp. e41831
    • Bray, K.1
  • 8
    • 84896733279 scopus 로고    scopus 로고
    • Mitochondrial dismissal in mammals, from protein degradation to mitophagy
    • Campello S., Strappazzon F., Cecconi F. Mitochondrial dismissal in mammals, from protein degradation to mitophagy. Biochim. Biophys. Acta 2014, 1837(4):451-460.
    • (2014) Biochim. Biophys. Acta , vol.1837 , Issue.4 , pp. 451-460
    • Campello, S.1    Strappazzon, F.2    Cecconi, F.3
  • 9
    • 84886018696 scopus 로고    scopus 로고
    • Tumor cells upregulate normoxic HIF-1alpha in response to doxorubicin
    • Cao Y., et al. Tumor cells upregulate normoxic HIF-1alpha in response to doxorubicin. Cancer Res. 2013, 73(20):6230-6242.
    • (2013) Cancer Res. , vol.73 , Issue.20 , pp. 6230-6242
    • Cao, Y.1
  • 10
    • 84862886876 scopus 로고    scopus 로고
    • Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis via glycolysis and ketone production
    • Capparelli C., et al. Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis via glycolysis and ketone production. Cell Cycle 2012, 11(12):2285-2302.
    • (2012) Cell Cycle , vol.11 , Issue.12 , pp. 2285-2302
    • Capparelli, C.1
  • 11
    • 33746891176 scopus 로고    scopus 로고
    • Mitochondrial DNA mutations in human cancer
    • Chatterjee A., Mambo E., Sidransky D. Mitochondrial DNA mutations in human cancer. Oncogene 2006, 25(34):4663-4674.
    • (2006) Oncogene , vol.25 , Issue.34 , pp. 4663-4674
    • Chatterjee, A.1    Mambo, E.2    Sidransky, D.3
  • 12
    • 82055185038 scopus 로고    scopus 로고
    • The gluttonous side of malignant melanoma: basic and clinical implications of macroautophagy
    • Checinska A., Soengas M.S. The gluttonous side of malignant melanoma: basic and clinical implications of macroautophagy. Pigment Cell Melanoma Res. 2011, 24(6):1116-1132.
    • (2011) Pigment Cell Melanoma Res. , vol.24 , Issue.6 , pp. 1116-1132
    • Checinska, A.1    Soengas, M.S.2
  • 13
    • 84876531457 scopus 로고    scopus 로고
    • PINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondria
    • Chen Y., Dorn G.W. PINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondria. Science 2013, 340(6131):471-475.
    • (2013) Science , vol.340 , Issue.6131 , pp. 471-475
    • Chen, Y.1    Dorn, G.W.2
  • 14
    • 79251577061 scopus 로고    scopus 로고
    • The regulation of autophagy-unanswered questions
    • Chen Y., Klionsky D.J. The regulation of autophagy-unanswered questions. J. Cell Sci. 2011, 124(Pt 2):161-170.
    • (2011) J. Cell Sci. , vol.124 , pp. 161-170
    • Chen, Y.1    Klionsky, D.J.2
  • 15
    • 84884812529 scopus 로고    scopus 로고
    • Why is autophagy important for melanoma? Molecular mechanisms and therapeutic implications
    • Corazzari M., et al. Why is autophagy important for melanoma? Molecular mechanisms and therapeutic implications. Semin. Cancer Biol. 2013, 23(5):337-343.
    • (2013) Semin. Cancer Biol. , vol.23 , Issue.5 , pp. 337-343
    • Corazzari, M.1
  • 16
    • 84880695780 scopus 로고    scopus 로고
    • Mitochondrial autophagy involving renal injury and aging is modulated by caloric intake in aged rat kidneys
    • Cui J., et al. Mitochondrial autophagy involving renal injury and aging is modulated by caloric intake in aged rat kidneys. PLoS One 2013, 8(7):e69720.
    • (2013) PLoS One , vol.8 , Issue.7 , pp. e69720
    • Cui, J.1
  • 17
    • 33745713171 scopus 로고    scopus 로고
    • Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis
    • Degenhardt K., et al. Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis. Cancer Cell 2006, 10(1):51-64.
    • (2006) Cancer Cell , vol.10 , Issue.1 , pp. 51-64
    • Degenhardt, K.1
  • 18
    • 55749090654 scopus 로고    scopus 로고
    • The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila
    • Deng H., et al. The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila. Proc. Natl. Acad. Sci. U. S. A. 2008, 105(38):14503-14508.
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , Issue.38 , pp. 14503-14508
    • Deng, H.1
  • 19
    • 84857041145 scopus 로고    scopus 로고
    • Shining a light on xeroderma pigmentosum
    • DiGiovanna J.J., Kraemer K.H. Shining a light on xeroderma pigmentosum. J. Invest. Dermatol. 2012, 132(3 Pt 2):785-796.
    • (2012) J. Invest. Dermatol. , vol.132 , Issue.3 , pp. 785-796
    • DiGiovanna, J.J.1    Kraemer, K.H.2
  • 20
    • 77956252454 scopus 로고    scopus 로고
    • Nix is critical to two distinct phases of mitophagy, reactive oxygen species-mediated autophagy induction and Parkin-ubiquitin-p62-mediated mitochondrial priming
    • Ding W.X., et al. Nix is critical to two distinct phases of mitophagy, reactive oxygen species-mediated autophagy induction and Parkin-ubiquitin-p62-mediated mitochondrial priming. J. Biol. Chem. 2010, 285(36):27879-27890.
    • (2010) J. Biol. Chem. , vol.285 , Issue.36 , pp. 27879-27890
    • Ding, W.X.1
  • 21
    • 79956039274 scopus 로고    scopus 로고
    • Receptor tyrosine kinases and their activation in melanoma
    • Easty D.J., et al. Receptor tyrosine kinases and their activation in melanoma. Pigment Cell Melanoma Res. 2011, 24(3):446-461.
    • (2011) Pigment Cell Melanoma Res. , vol.24 , Issue.3 , pp. 446-461
    • Easty, D.J.1
  • 22
    • 84896698630 scopus 로고    scopus 로고
    • Cutaneous melanoma
    • Eggermont A.M., Spatz A., Robert C. Cutaneous melanoma. Lancet 2014, 383(9919):816-827.
    • (2014) Lancet , vol.383 , Issue.9919 , pp. 816-827
    • Eggermont, A.M.1    Spatz, A.2    Robert, C.3
  • 23
    • 84876501668 scopus 로고    scopus 로고
    • Parkinson's disease: from genetics to treatments
    • Fan H.C., et al. Parkinson's disease: from genetics to treatments. Cell Transplant. 2013, 22(4):639-652.
    • (2013) Cell Transplant. , vol.22 , Issue.4 , pp. 639-652
    • Fan, H.C.1
  • 24
    • 84900344357 scopus 로고    scopus 로고
    • Defective mitophagy in XPA via PARP-1 hyperactivation and NAD(+)/SIRT1 reduction
    • Fang E.F., et al. Defective mitophagy in XPA via PARP-1 hyperactivation and NAD(+)/SIRT1 reduction. Cell 2014, 157(4):882-896.
    • (2014) Cell , vol.157 , Issue.4 , pp. 882-896
    • Fang, E.F.1
  • 25
    • 80054844842 scopus 로고    scopus 로고
    • ER tubules mark sites of mitochondrial division
    • Friedman J.R., et al. ER tubules mark sites of mitochondrial division. Science 2011, 334(6054):358-362.
    • (2011) Science , vol.334 , Issue.6054 , pp. 358-362
    • Friedman, J.R.1
  • 26
    • 84876524198 scopus 로고    scopus 로고
    • Regulation of mitophagy by the Gp78 E3 ubiquitin ligase
    • Fu M., et al. Regulation of mitophagy by the Gp78 E3 ubiquitin ligase. Mol. Biol. Cell 2013, 24(8):1153-1162.
    • (2013) Mol. Biol. Cell , vol.24 , Issue.8 , pp. 1153-1162
    • Fu, M.1
  • 27
    • 77749306132 scopus 로고    scopus 로고
    • Mitochondrial content and distribution changes specific to mouse diaphragm after chronic normobaric hypoxia
    • Gamboa J.L., Andrade F.H. Mitochondrial content and distribution changes specific to mouse diaphragm after chronic normobaric hypoxia. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2010, 298(3):R575-R583.
    • (2010) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.298 , Issue.3 , pp. R575-R583
    • Gamboa, J.L.1    Andrade, F.H.2
  • 28
    • 57449086541 scopus 로고    scopus 로고
    • Melanoma epidemiology and trends
    • Garbe C., Leiter U. Melanoma epidemiology and trends. Clin. Dermatol. 2009, 27(1):3-9.
    • (2009) Clin. Dermatol. , vol.27 , Issue.1 , pp. 3-9
    • Garbe, C.1    Leiter, U.2
  • 29
    • 75949130828 scopus 로고    scopus 로고
    • PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
    • Geisler S., et al. PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1. Nat. Cell Biol. 2010, 12(2):119-131.
    • (2010) Nat. Cell Biol. , vol.12 , Issue.2 , pp. 119-131
    • Geisler, S.1
  • 30
    • 66749163493 scopus 로고    scopus 로고
    • Parkinson phenotype in aged PINK1-deficient mice is accompanied by progressive mitochondrial dysfunction in absence of neurodegeneration
    • Gispert S., et al. Parkinson phenotype in aged PINK1-deficient mice is accompanied by progressive mitochondrial dysfunction in absence of neurodegeneration. PLoS One 2009, 4(6):e5777.
    • (2009) PLoS One , vol.4 , Issue.6 , pp. e5777
    • Gispert, S.1
  • 31
    • 84864015441 scopus 로고    scopus 로고
    • BNip3 regulates mitochondrial function and lipid metabolism in the liver
    • Glick D., et al. BNip3 regulates mitochondrial function and lipid metabolism in the liver. Mol. Cell Biol. 2012, 32(13):2570-2584.
    • (2012) Mol. Cell Biol. , vol.32 , Issue.13 , pp. 2570-2584
    • Glick, D.1
  • 32
    • 33847220364 scopus 로고    scopus 로고
    • Melanoma biology and new targeted therapy
    • Gray-Schopfer V., Wellbrock C., Marais R. Melanoma biology and new targeted therapy. Nature 2007, 445(7130):851-857.
    • (2007) Nature , vol.445 , Issue.7130 , pp. 851-857
    • Gray-Schopfer, V.1    Wellbrock, C.2    Marais, R.3
  • 33
    • 79952228407 scopus 로고    scopus 로고
    • Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis
    • Guo J.Y., et al. Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis. Genes Dev. 2011, 25(5):460-470.
    • (2011) Genes Dev. , vol.25 , Issue.5 , pp. 460-470
    • Guo, J.Y.1
  • 34
    • 84875365804 scopus 로고    scopus 로고
    • Autophagosomes form at ER-mitochondria contact sites
    • Hamasaki M., et al. Autophagosomes form at ER-mitochondria contact sites. Nature 2013, 495(7441):389-393.
    • (2013) Nature , vol.495 , Issue.7441 , pp. 389-393
    • Hamasaki, M.1
  • 35
    • 84861733247 scopus 로고    scopus 로고
    • Microtubule-associated protein 1 light chain 3 (LC3) interacts with Bnip3 protein to selectively remove endoplasmic reticulum and mitochondria via autophagy
    • Hanna R.A., et al. Microtubule-associated protein 1 light chain 3 (LC3) interacts with Bnip3 protein to selectively remove endoplasmic reticulum and mitochondria via autophagy. J. Biol. Chem. 2012, 287(23):19094-19104.
    • (2012) J. Biol. Chem. , vol.287 , Issue.23 , pp. 19094-19104
    • Hanna, R.A.1
  • 36
    • 84876436850 scopus 로고    scopus 로고
    • Oncogenic BRAF regulates oxidative metabolism via PGC1alpha and MITF
    • Haq R., et al. Oncogenic BRAF regulates oxidative metabolism via PGC1alpha and MITF. Cancer Cell 2013, 23(3):302-315.
    • (2013) Cancer Cell , vol.23 , Issue.3 , pp. 302-315
    • Haq, R.1
  • 37
    • 84857885730 scopus 로고    scopus 로고
    • Overexpression of autophagy-related beclin-1 in advanced malignant melanoma and its low expression in melanoma-in-situ
    • Hara Y., Nakamura M. Overexpression of autophagy-related beclin-1 in advanced malignant melanoma and its low expression in melanoma-in-situ. Eur. J. Dermatol. 2012, 22(1):128-129.
    • (2012) Eur. J. Dermatol. , vol.22 , Issue.1 , pp. 128-129
    • Hara, Y.1    Nakamura, M.2
  • 38
    • 84890429468 scopus 로고    scopus 로고
    • High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy
    • Hasson S.A., et al. High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy. Nature 2013, 504(7479):291-295.
    • (2013) Nature , vol.504 , Issue.7479 , pp. 291-295
    • Hasson, S.A.1
  • 39
    • 0019963097 scopus 로고
    • Comparison of macromelanosomes and autophagic giant melanosome complexes in nevocellular nevi, lentigo simplex and malignant melanoma
    • Horikoshi T., Jimbow K., Sugiyama S. Comparison of macromelanosomes and autophagic giant melanosome complexes in nevocellular nevi, lentigo simplex and malignant melanoma. J. Cutan. Pathol. 1982, 9(5):329-339.
    • (1982) J. Cutan. Pathol. , vol.9 , Issue.5 , pp. 329-339
    • Horikoshi, T.1    Jimbow, K.2    Sugiyama, S.3
  • 40
    • 84881619807 scopus 로고    scopus 로고
    • Sestrin-2 and BNIP3 regulate autophagy and mitophagy in renal tubular cells in acute kidney injury
    • Ishihara M., et al. Sestrin-2 and BNIP3 regulate autophagy and mitophagy in renal tubular cells in acute kidney injury. Am. J. Physiol. Ren. Physiol. 2013, 305(4):F495-F509.
    • (2013) Am. J. Physiol. Ren. Physiol. , vol.305 , Issue.4 , pp. F495-F509
    • Ishihara, M.1
  • 41
    • 84857850213 scopus 로고    scopus 로고
    • Structures containing Atg9A and the ULK1 complex independently target depolarized mitochondria at initial stages of Parkin-mediated mitophagy
    • Itakura E., et al. Structures containing Atg9A and the ULK1 complex independently target depolarized mitochondria at initial stages of Parkin-mediated mitophagy. J. Cell Sci. 2012, 125(Pt 6):1488-1499.
    • (2012) J. Cell Sci. , vol.125 , pp. 1488-1499
    • Itakura, E.1
  • 42
    • 84855590085 scopus 로고    scopus 로고
    • Targeting the RAS pathway in melanoma
    • Ji Z., Flaherty K.T., Tsao H. Targeting the RAS pathway in melanoma. Trends Mol. Med. 2012, 18(1):27-35.
    • (2012) Trends Mol. Med. , vol.18 , Issue.1 , pp. 27-35
    • Ji, Z.1    Flaherty, K.T.2    Tsao, H.3
  • 43
    • 84887486172 scopus 로고    scopus 로고
    • The accumulation of misfolded proteins in the mitochondrial matrix is sensed by PINK1 to induce PARK2/Parkin-mediated mitophagy of polarized mitochondria
    • Jin S.M., Youle R.J. The accumulation of misfolded proteins in the mitochondrial matrix is sensed by PINK1 to induce PARK2/Parkin-mediated mitophagy of polarized mitochondria. Autophagy 2013, 9(11):1750-1757.
    • (2013) Autophagy , vol.9 , Issue.11 , pp. 1750-1757
    • Jin, S.M.1    Youle, R.J.2
  • 44
    • 78649685455 scopus 로고    scopus 로고
    • Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL
    • Jin S.M., et al. Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL. J. Cell Biol. 2010, 191(5):933-942.
    • (2010) J. Cell Biol. , vol.191 , Issue.5 , pp. 933-942
    • Jin, S.M.1
  • 45
    • 80051622129 scopus 로고    scopus 로고
    • H-ras up-regulates expression of BNIP3
    • Kalas W., et al. H-ras up-regulates expression of BNIP3. Anticancer Res. 2011, 31(9):2869-2875.
    • (2011) Anticancer Res. , vol.31 , Issue.9 , pp. 2869-2875
    • Kalas, W.1
  • 47
    • 84883487916 scopus 로고    scopus 로고
    • Casein kinase 2 is essential for mitophagy
    • Kanki T., et al. Casein kinase 2 is essential for mitophagy. EMBO Rep. 2013, 14(9):788-794.
    • (2013) EMBO Rep. , vol.14 , Issue.9 , pp. 788-794
    • Kanki, T.1
  • 48
    • 40649126759 scopus 로고    scopus 로고
    • MTOR is activated in the majority of malignant melanomas
    • Karbowniczek M., et al. mTOR is activated in the majority of malignant melanomas. J. Invest. Dermatol. 2008, 128(4):980-987.
    • (2008) J. Invest. Dermatol. , vol.128 , Issue.4 , pp. 980-987
    • Karbowniczek, M.1
  • 50
    • 56049091236 scopus 로고    scopus 로고
    • PINK1 controls mitochondrial localization of Parkin through direct phosphorylation
    • Kim Y., et al. PINK1 controls mitochondrial localization of Parkin through direct phosphorylation. Biochem. Biophys. Res. Commun. 2008, 377(3):975-980.
    • (2008) Biochem. Biophys. Res. Commun. , vol.377 , Issue.3 , pp. 975-980
    • Kim, Y.1
  • 51
    • 84878943669 scopus 로고    scopus 로고
    • The mechanism and physiological function of macroautophagy
    • Klionsky D.J., Codogno P. The mechanism and physiological function of macroautophagy. J. Innate Immun. 2013, 5(5):427-433.
    • (2013) J. Innate Immun. , vol.5 , Issue.5 , pp. 427-433
    • Klionsky, D.J.1    Codogno, P.2
  • 52
    • 36849089101 scopus 로고    scopus 로고
    • Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice
    • Komatsu M., et al. Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice. Cell 2007, 131(6):1149-1163.
    • (2007) Cell , vol.131 , Issue.6 , pp. 1149-1163
    • Komatsu, M.1
  • 53
    • 84878537792 scopus 로고    scopus 로고
    • Route to destruction: autophagosomes SNARE lysosomes
    • Kramer H. Route to destruction: autophagosomes SNARE lysosomes. J. Cell Biol. 2013, 201(4):495-497.
    • (2013) J. Cell Biol. , vol.201 , Issue.4 , pp. 495-497
    • Kramer, H.1
  • 54
    • 77949486311 scopus 로고    scopus 로고
    • Constitutive HIF-1 activity in malignant melanoma
    • Kuphal S., et al. Constitutive HIF-1 activity in malignant melanoma. Eur. J. Cancer 2010, 46(6):1159-1169.
    • (2010) Eur. J. Cancer , vol.46 , Issue.6 , pp. 1159-1169
    • Kuphal, S.1
  • 55
    • 77953123212 scopus 로고    scopus 로고
    • The BH3-only Bnip3 binds to the dynamin Opa1 to promote mitochondrial fragmentation and apoptosis by distinct mechanisms
    • Landes T., et al. The BH3-only Bnip3 binds to the dynamin Opa1 to promote mitochondrial fragmentation and apoptosis by distinct mechanisms. EMBO Rep. 2010, 11(6):459-465.
    • (2010) EMBO Rep. , vol.11 , Issue.6 , pp. 459-465
    • Landes, T.1
  • 56
    • 74049101149 scopus 로고    scopus 로고
    • Autophagy in cutaneous malignant melanoma
    • Lazova R., Klump V., Pawelek J. Autophagy in cutaneous malignant melanoma. J. Cutan. Pathol. 2010, 37(2):256-268.
    • (2010) J. Cutan. Pathol. , vol.37 , Issue.2 , pp. 256-268
    • Lazova, R.1    Klump, V.2    Pawelek, J.3
  • 57
    • 84856003912 scopus 로고    scopus 로고
    • Punctate LC3B expression is a common feature of solid tumors and associated with proliferation, metastasis, and poor outcome
    • Lazova R., et al. Punctate LC3B expression is a common feature of solid tumors and associated with proliferation, metastasis, and poor outcome. Clin. Cancer Res. 2012, 18(2):370-379.
    • (2012) Clin. Cancer Res. , vol.18 , Issue.2 , pp. 370-379
    • Lazova, R.1
  • 58
    • 80355127945 scopus 로고    scopus 로고
    • Mitochondrial autophagy by Bnip3 involves Drp1-mediated mitochondrial fission and recruitment of Parkin in cardiac myocytes
    • Lee Y., et al. Mitochondrial autophagy by Bnip3 involves Drp1-mediated mitochondrial fission and recruitment of Parkin in cardiac myocytes. Am. J. Physiol. Heart Circ. Physiol. 2011, 301(5):H1924-H1931.
    • (2011) Am. J. Physiol. Heart Circ. Physiol. , vol.301 , Issue.5 , pp. H1924-H1931
    • Lee, Y.1
  • 59
    • 37248999267 scopus 로고    scopus 로고
    • Bnip3 mediates the hypoxia-induced inhibition on mammalian target of rapamycin by interacting with Rheb
    • Li Y., et al. Bnip3 mediates the hypoxia-induced inhibition on mammalian target of rapamycin by interacting with Rheb. J. Biol. Chem. 2007, 282(49):35803-35813.
    • (2007) J. Biol. Chem. , vol.282 , Issue.49 , pp. 35803-35813
    • Li, Y.1
  • 60
    • 84898619521 scopus 로고    scopus 로고
    • MicroRNA-137 is a novel hypoxia-responsive microRNA that inhibits mitophagy via regulation of two mitophagy receptors FUNDC1 and NIX
    • Li W., et al. MicroRNA-137 is a novel hypoxia-responsive microRNA that inhibits mitophagy via regulation of two mitophagy receptors FUNDC1 and NIX. J. Biol. Chem. 2014, 289(15):10691-10701.
    • (2014) J. Biol. Chem. , vol.289 , Issue.15 , pp. 10691-10701
    • Li, W.1
  • 61
    • 84862789618 scopus 로고    scopus 로고
    • Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells
    • Liu L., et al. Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells. Nat. Cell Biol. 2012, 14(2):177-185.
    • (2012) Nat. Cell Biol. , vol.14 , Issue.2 , pp. 177-185
    • Liu, L.1
  • 62
    • 84884693919 scopus 로고    scopus 로고
    • Down-regulation of autophagy-related protein 5 (ATG5) contributes to the pathogenesis of early-stage cutaneous melanoma
    • 202ra123
    • Liu H., et al. Down-regulation of autophagy-related protein 5 (ATG5) contributes to the pathogenesis of early-stage cutaneous melanoma. Sci. Transl. Med. 2013, 5(202):202ra123.
    • (2013) Sci. Transl. Med. , vol.5 , Issue.202
    • Liu, H.1
  • 63
    • 84894483685 scopus 로고    scopus 로고
    • Autophagy suppresses melanoma tumorigenesis by inducing senescence
    • Liu H., He Z., Simon H.U. Autophagy suppresses melanoma tumorigenesis by inducing senescence. Autophagy 2014, 10(2):372-373.
    • (2014) Autophagy , vol.10 , Issue.2 , pp. 372-373
    • Liu, H.1    He, Z.2    Simon, H.U.3
  • 64
    • 78751511180 scopus 로고    scopus 로고
    • Autophagy facilitates glycolysis during Ras-mediated oncogenic transformation
    • Lock R., et al. Autophagy facilitates glycolysis during Ras-mediated oncogenic transformation. Mol. Biol. Cell 2010, 22(2):165-178.
    • (2010) Mol. Biol. Cell , vol.22 , Issue.2 , pp. 165-178
    • Lock, R.1
  • 65
    • 79956003662 scopus 로고    scopus 로고
    • Measurements of tumor cell autophagy predict invasiveness, resistance to chemotherapy, and survival in melanoma
    • Ma X.H., et al. Measurements of tumor cell autophagy predict invasiveness, resistance to chemotherapy, and survival in melanoma. Clin. Cancer Res. 2011, 17(10):3478-3489.
    • (2011) Clin. Cancer Res. , vol.17 , Issue.10 , pp. 3478-3489
    • Ma, X.H.1
  • 66
    • 84896757312 scopus 로고    scopus 로고
    • Targeting ER stress-induced autophagy overcomes BRAF inhibitor resistance in melanoma
    • Ma X.H., et al. Targeting ER stress-induced autophagy overcomes BRAF inhibitor resistance in melanoma. J. Clin. Invest. 2014, 124(3):1406-1417.
    • (2014) J. Clin. Invest. , vol.124 , Issue.3 , pp. 1406-1417
    • Ma, X.H.1
  • 67
    • 84879780600 scopus 로고    scopus 로고
    • Autophagy: shaping the tumor microenvironment and therapeutic response
    • Maes H., et al. Autophagy: shaping the tumor microenvironment and therapeutic response. Trends Mol. Med. 2013, 19(7):428-446.
    • (2013) Trends Mol. Med. , vol.19 , Issue.7 , pp. 428-446
    • Maes, H.1
  • 68
    • 84893205512 scopus 로고    scopus 로고
    • Dynamic interplay between autophagic flux and Akt during melanoma progression in vitro
    • Maes H., et al. Dynamic interplay between autophagic flux and Akt during melanoma progression in vitro. Exp. Dermatol. 2014, 23(2):101-106.
    • (2014) Exp. Dermatol. , vol.23 , Issue.2 , pp. 101-106
    • Maes, H.1
  • 69
    • 84897390838 scopus 로고    scopus 로고
    • BNIP3 supports melanoma cell migration and vasculogenic mimicry by orchestrating the actin cytoskeleton
    • Maes H., et al. BNIP3 supports melanoma cell migration and vasculogenic mimicry by orchestrating the actin cytoskeleton. Cell Death Dis. 2014, 5:e1127.
    • (2014) Cell Death Dis. , vol.5 , pp. e1127
    • Maes, H.1
  • 70
    • 36448940798 scopus 로고    scopus 로고
    • FoxO3 controls autophagy in skeletal muscle in vivo
    • Mammucari C., et al. FoxO3 controls autophagy in skeletal muscle in vivo. Cell Metab. 2007, 6(6):458-471.
    • (2007) Cell Metab. , vol.6 , Issue.6 , pp. 458-471
    • Mammucari, C.1
  • 71
    • 84880506979 scopus 로고    scopus 로고
    • The scaffold protein Atg11 recruits fission machinery to drive selective mitochondria degradation by autophagy
    • Mao K., et al. The scaffold protein Atg11 recruits fission machinery to drive selective mitochondria degradation by autophagy. Dev. Cell 2013, 26(1):9-18.
    • (2013) Dev. Cell , vol.26 , Issue.1 , pp. 9-18
    • Mao, K.1
  • 72
    • 84865800743 scopus 로고    scopus 로고
    • Autophagy is a protective mechanism for human melanoma cells under acidic stress
    • Marino M.L., et al. Autophagy is a protective mechanism for human melanoma cells under acidic stress. J. Biol. Chem. 2012, 287(36):30664-30676.
    • (2012) J. Biol. Chem. , vol.287 , Issue.36 , pp. 30664-30676
    • Marino, M.L.1
  • 73
    • 84894565195 scopus 로고    scopus 로고
    • Self-consumption: the interplay of autophagy and apoptosis
    • Marino G., et al. Self-consumption: the interplay of autophagy and apoptosis. Nat. Rev. Mol. Cell Biol. 2014, 15(2):81-94.
    • (2014) Nat. Rev. Mol. Cell Biol. , vol.15 , Issue.2 , pp. 81-94
    • Marino, G.1
  • 74
    • 66449099090 scopus 로고    scopus 로고
    • Autophagy suppresses tumorigenesis through elimination of p62
    • Mathew R., et al. Autophagy suppresses tumorigenesis through elimination of p62. Cell 2009, 137(6):1062-1075.
    • (2009) Cell , vol.137 , Issue.6 , pp. 1062-1075
    • Mathew, R.1
  • 75
    • 84857267849 scopus 로고    scopus 로고
    • Chloroquine sensitizes breast cancer cells to chemotherapy independent of autophagy
    • Maycotte P., et al. Chloroquine sensitizes breast cancer cells to chemotherapy independent of autophagy. Autophagy 2012, 8(2):200-212.
    • (2012) Autophagy , vol.8 , Issue.2 , pp. 200-212
    • Maycotte, P.1
  • 76
    • 69449107689 scopus 로고    scopus 로고
    • Atypical BH3-domains of BNIP3 and BNIP3L lead to autophagy in hypoxia
    • Mazure N.M., Pouyssegur J. Atypical BH3-domains of BNIP3 and BNIP3L lead to autophagy in hypoxia. Autophagy 2009, 5(6):868-869.
    • (2009) Autophagy , vol.5 , Issue.6 , pp. 868-869
    • Mazure, N.M.1    Pouyssegur, J.2
  • 77
    • 84877578621 scopus 로고    scopus 로고
    • Rheb regulates mitophagy induced by mitochondrial energetic status
    • Melser S., et al. Rheb regulates mitophagy induced by mitochondrial energetic status. Cell Metab. 2013, 17(5):719-730.
    • (2013) Cell Metab. , vol.17 , Issue.5 , pp. 719-730
    • Melser, S.1
  • 78
    • 77649335850 scopus 로고    scopus 로고
    • Beclin 1 and LC3 autophagic gene expression in cutaneous melanocytic lesions
    • Miracco C., et al. Beclin 1 and LC3 autophagic gene expression in cutaneous melanocytic lesions. Hum. Pathol. 2010, 41(4):503-512.
    • (2010) Hum. Pathol. , vol.41 , Issue.4 , pp. 503-512
    • Miracco, C.1
  • 79
    • 81055144784 scopus 로고    scopus 로고
    • Autophagy: renovation of cells and tissues
    • Mizushima N., Komatsu M. Autophagy: renovation of cells and tissues. Cell 2011, 147(4):728-741.
    • (2011) Cell , vol.147 , Issue.4 , pp. 728-741
    • Mizushima, N.1    Komatsu, M.2
  • 80
    • 57749100375 scopus 로고    scopus 로고
    • Mitochondrial function and morphology are impaired in parkin-mutant fibroblasts
    • Mortiboys H., et al. Mitochondrial function and morphology are impaired in parkin-mutant fibroblasts. Ann. Neurol. 2008, 64(5):555-565.
    • (2008) Ann. Neurol. , vol.64 , Issue.5 , pp. 555-565
    • Mortiboys, H.1
  • 81
    • 74049153002 scopus 로고    scopus 로고
    • Nix is a selective autophagy receptor for mitochondrial clearance
    • Novak I., et al. Nix is a selective autophagy receptor for mitochondrial clearance. EMBO Rep. 2010, 11(1):45-51.
    • (2010) EMBO Rep. , vol.11 , Issue.1 , pp. 45-51
    • Novak, I.1
  • 82
    • 84868384387 scopus 로고    scopus 로고
    • Mitochondrial hexokinase HKI is a novel substrate of the Parkin ubiquitin ligase
    • Okatsu K., et al. Mitochondrial hexokinase HKI is a novel substrate of the Parkin ubiquitin ligase. Biochem. Biophys. Res. Commun. 2012, 428(1):197-202.
    • (2012) Biochem. Biophys. Res. Commun. , vol.428 , Issue.1 , pp. 197-202
    • Okatsu, K.1
  • 83
    • 84890957474 scopus 로고    scopus 로고
    • A dimeric PINK1-containing complex on depolarized mitochondria stimulates Parkin recruitment
    • Okatsu K., et al. A dimeric PINK1-containing complex on depolarized mitochondria stimulates Parkin recruitment. J. Biol. Chem. 2013, 288(51):36372-36384.
    • (2013) J. Biol. Chem. , vol.288 , Issue.51 , pp. 36372-36384
    • Okatsu, K.1
  • 84
    • 84875581921 scopus 로고    scopus 로고
    • Fis1 acts as a mitochondrial recruitment factor for TBC1D15 that is involved in regulation of mitochondrial morphology
    • Onoue K., et al. Fis1 acts as a mitochondrial recruitment factor for TBC1D15 that is involved in regulation of mitochondrial morphology. J. Cell Sci. 2013, 126(Pt 1):176-185.
    • (2013) J. Cell Sci. , vol.126 , pp. 176-185
    • Onoue, K.1
  • 85
    • 82555187810 scopus 로고    scopus 로고
    • Image-based genome-wide siRNA screen identifies selective autophagy factors
    • Orvedahl A., et al. Image-based genome-wide siRNA screen identifies selective autophagy factors. Nature 2011, 480(7375):113-117.
    • (2011) Nature , vol.480 , Issue.7375 , pp. 113-117
    • Orvedahl, A.1
  • 86
    • 77952672872 scopus 로고    scopus 로고
    • Bnip3 mediates permeabilization of mitochondria and release of cytochrome c via a novel mechanism
    • Quinsay M.N., et al. Bnip3 mediates permeabilization of mitochondria and release of cytochrome c via a novel mechanism. J. Mol. Cell. Cardiol. 2010, 48(6):1146-1156.
    • (2010) J. Mol. Cell. Cardiol. , vol.48 , Issue.6 , pp. 1146-1156
    • Quinsay, M.N.1
  • 87
    • 78649704325 scopus 로고    scopus 로고
    • Autophagy and metabolism
    • Rabinowitz J.D., White E. Autophagy and metabolism. Science. 2010, 330(6009):1344-1348.
    • (2010) Science. , vol.330 , Issue.6009 , pp. 1344-1348
    • Rabinowitz, J.D.1    White, E.2
  • 88
    • 77955637249 scopus 로고    scopus 로고
    • ATG12 conjugation to ATG3 regulates mitochondrial homeostasis and cell death
    • Radoshevich L., et al. ATG12 conjugation to ATG3 regulates mitochondrial homeostasis and cell death. Cell 2010, 142(4):590-600.
    • (2010) Cell , vol.142 , Issue.4 , pp. 590-600
    • Radoshevich, L.1
  • 89
    • 79952617818 scopus 로고    scopus 로고
    • Bnip3 impairs mitochondrial bioenergetics and stimulates mitochondrial turnover
    • Rikka S., et al. Bnip3 impairs mitochondrial bioenergetics and stimulates mitochondrial turnover. Cell Death Differ. 2010, 18(4):721-731.
    • (2010) Cell Death Differ. , vol.18 , Issue.4 , pp. 721-731
    • Rikka, S.1
  • 90
    • 84892859905 scopus 로고    scopus 로고
    • Interactions between autophagy receptors and ubiquitin-like proteins form the molecular basis for selective autophagy
    • Rogov V., et al. Interactions between autophagy receptors and ubiquitin-like proteins form the molecular basis for selective autophagy. Mol. Cell 2014, 53(2):167-178.
    • (2014) Mol. Cell , vol.53 , Issue.2 , pp. 167-178
    • Rogov, V.1
  • 91
    • 79957883170 scopus 로고    scopus 로고
    • The multiple roles of autophagy in cancer
    • Rosenfeldt M.T., Ryan K.M. The multiple roles of autophagy in cancer. Carcinogenesis 2011, 32(7):955-963.
    • (2011) Carcinogenesis , vol.32 , Issue.7 , pp. 955-963
    • Rosenfeldt, M.T.1    Ryan, K.M.2
  • 92
    • 84890432985 scopus 로고    scopus 로고
    • P53 status determines the role of autophagy in pancreatic tumour development
    • Rosenfeldt M.T., et al. p53 status determines the role of autophagy in pancreatic tumour development. Nature 2013, 504(7479):296-300.
    • (2013) Nature , vol.504 , Issue.7479 , pp. 296-300
    • Rosenfeldt, M.T.1
  • 93
    • 84866122688 scopus 로고    scopus 로고
    • Autophagy modulation as a potential therapeutic target for diverse diseases
    • Rubinsztein D.C., Codogno P., Levine B. Autophagy modulation as a potential therapeutic target for diverse diseases. Nat. Rev. Drug Discov. 2012, 11(9):709-730.
    • (2012) Nat. Rev. Drug Discov. , vol.11 , Issue.9 , pp. 709-730
    • Rubinsztein, D.C.1    Codogno, P.2    Levine, B.3
  • 94
    • 47049100413 scopus 로고    scopus 로고
    • Essential role for Nix in autophagic maturation of erythroid cells
    • Sandoval H., et al. Essential role for Nix in autophagic maturation of erythroid cells. Nature 2008, 454(7201):232-235.
    • (2008) Nature , vol.454 , Issue.7201 , pp. 232-235
    • Sandoval, H.1
  • 95
    • 37649017266 scopus 로고    scopus 로고
    • NIX is required for programmed mitochondrial clearance during reticulocyte maturation
    • Schweers R.L., et al. NIX is required for programmed mitochondrial clearance during reticulocyte maturation. Proc. Natl. Acad. Sci. U. S. A. 2007, 104(49):19500-19505.
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , Issue.49 , pp. 19500-19505
    • Schweers, R.L.1
  • 96
    • 79955786943 scopus 로고    scopus 로고
    • Mitochondrial Parkin recruitment is impaired in neurons derived from mutant PINK1 induced pluripotent stem cells
    • Seibler P., et al. Mitochondrial Parkin recruitment is impaired in neurons derived from mutant PINK1 induced pluripotent stem cells. J. Neurosci. 2011, 31(16):5970-5976.
    • (2011) J. Neurosci. , vol.31 , Issue.16 , pp. 5970-5976
    • Seibler, P.1
  • 97
    • 80955177196 scopus 로고    scopus 로고
    • TFEB links autophagy to lysosomal biogenesis
    • Settembre C., et al. TFEB links autophagy to lysosomal biogenesis. Science 2011, 332(6036):1429-1433.
    • (2011) Science , vol.332 , Issue.6036 , pp. 1429-1433
    • Settembre, C.1
  • 98
    • 79955961530 scopus 로고    scopus 로고
    • Defective regulation of autophagy upon leucine deprivation reveals a targetable liability of human melanoma cells in vitro and in vivo
    • Sheen J.H., et al. Defective regulation of autophagy upon leucine deprivation reveals a targetable liability of human melanoma cells in vitro and in vivo. Cancer Cell 2011, 19(5):613-628.
    • (2011) Cancer Cell , vol.19 , Issue.5 , pp. 613-628
    • Sheen, J.H.1
  • 99
    • 84891822234 scopus 로고    scopus 로고
    • Mutations in Fis1 disrupt orderly disposal of defective mitochondria
    • Shen Q., et al. Mutations in Fis1 disrupt orderly disposal of defective mitochondria. Mol. Biol. Cell 2014, 25(1):145-159.
    • (2014) Mol. Biol. Cell , vol.25 , Issue.1 , pp. 145-159
    • Shen, Q.1
  • 100
    • 84867918691 scopus 로고    scopus 로고
    • Mitophagy or how to control the Jekyll and Hyde embedded in mitochondrial metabolism: implications for melanoma progression and drug resistance
    • Soengas M.S. Mitophagy or how to control the Jekyll and Hyde embedded in mitochondrial metabolism: implications for melanoma progression and drug resistance. Pigment Cell Melanoma Res. 2012, 25(6):721-731.
    • (2012) Pigment Cell Melanoma Res. , vol.25 , Issue.6 , pp. 721-731
    • Soengas, M.S.1
  • 101
    • 0035884701 scopus 로고    scopus 로고
    • HIF-1-dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors
    • Sowter H.M., et al. HIF-1-dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors. Cancer Res. 2001, 61(18):6669-6673.
    • (2001) Cancer Res. , vol.61 , Issue.18 , pp. 6669-6673
    • Sowter, H.M.1
  • 102
    • 82755161734 scopus 로고    scopus 로고
    • Autophagy and disease: always two sides to a problem
    • Sridhar S., et al. Autophagy and disease: always two sides to a problem. J. Pathol. 2011, 226(2):255-273.
    • (2011) J. Pathol. , vol.226 , Issue.2 , pp. 255-273
    • Sridhar, S.1
  • 103
    • 84885350394 scopus 로고    scopus 로고
    • Autophagy sustains mitochondrial glutamine metabolism and growth of BrafV600E-driven lung tumors
    • Strohecker A.M., et al. Autophagy sustains mitochondrial glutamine metabolism and growth of BrafV600E-driven lung tumors. Cancer Discov. 2013, 3(11):1272-1285.
    • (2013) Cancer Discov. , vol.3 , Issue.11 , pp. 1272-1285
    • Strohecker, A.M.1
  • 104
    • 67651152483 scopus 로고    scopus 로고
    • Targeted activation of innate immunity for therapeutic induction of autophagy and apoptosis in melanoma cells
    • Tormo D., et al. Targeted activation of innate immunity for therapeutic induction of autophagy and apoptosis in melanoma cells. Cancer Cell 2009, 16(2):103-114.
    • (2009) Cancer Cell , vol.16 , Issue.2 , pp. 103-114
    • Tormo, D.1
  • 105
    • 84899920605 scopus 로고    scopus 로고
    • Mitochondrial impairment observed in fibroblasts from South African Parkinson's disease patients with parkin mutations
    • van der Merwe C., et al. Mitochondrial impairment observed in fibroblasts from South African Parkinson's disease patients with parkin mutations. Biochem. Biophys. Res. Commun. 2014, 447(2):334-340.
    • (2014) Biochem. Biophys. Res. Commun. , vol.447 , Issue.2 , pp. 334-340
    • van der Merwe, C.1
  • 106
    • 84904967279 scopus 로고    scopus 로고
    • New functions of mitochondria associated membranes in cellular signaling
    • (Epub ahead of print)
    • van Vliet A.R., Verfaillie T., Agostinis P. New functions of mitochondria associated membranes in cellular signaling. Biochim. Biophys. Acta 2014, (Epub ahead of print). 10.1016/j.bbamcr.2014.03.009.
    • (2014) Biochim. Biophys. Acta
    • van Vliet, A.R.1    Verfaillie, T.2    Agostinis, P.3
  • 107
    • 84876448550 scopus 로고    scopus 로고
    • PGC1alpha expression defines a subset of human melanoma tumors with increased mitochondrial capacity and resistance to oxidative stress
    • Vazquez F., et al. PGC1alpha expression defines a subset of human melanoma tumors with increased mitochondrial capacity and resistance to oxidative stress. Cancer Cell 2013, 23(3):287-301.
    • (2013) Cancer Cell , vol.23 , Issue.3 , pp. 287-301
    • Vazquez, F.1
  • 108
    • 84876213313 scopus 로고    scopus 로고
    • The PINK1-Parkin pathway promotes both mitophagy and selective respiratory chain turnover in vivo
    • Vincow E.S., et al. The PINK1-Parkin pathway promotes both mitophagy and selective respiratory chain turnover in vivo. Proc. Natl. Acad. Sci. U. S. A. 2013, 110(16):6400-6405.
    • (2013) Proc. Natl. Acad. Sci. U. S. A. , vol.110 , Issue.16 , pp. 6400-6405
    • Vincow, E.S.1
  • 109
    • 81055140895 scopus 로고    scopus 로고
    • PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility
    • Wang X., et al. PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility. Cell 2011, 147(4):893-906.
    • (2011) Cell , vol.147 , Issue.4 , pp. 893-906
    • Wang, X.1
  • 110
    • 84861526009 scopus 로고    scopus 로고
    • Deconvoluting the context-dependent role for autophagy in cancer
    • White E. Deconvoluting the context-dependent role for autophagy in cancer. Nat. Rev. Cancer 2012, 12(6):401-410.
    • (2012) Nat. Rev. Cancer , vol.12 , Issue.6 , pp. 401-410
    • White, E.1
  • 111
    • 84855500993 scopus 로고    scopus 로고
    • Autophagy: for better or for worse
    • Wirawan E., et al. Autophagy: for better or for worse. Cell Res. 2012, 22(1):43-61.
    • (2012) Cell Res. , vol.22 , Issue.1 , pp. 43-61
    • Wirawan, E.1
  • 112
    • 84899789746 scopus 로고    scopus 로고
    • ULK1 translocates to mitochondria and phosphorylates FUNDC1 to regulate mitophagy
    • Wu W., et al. ULK1 translocates to mitochondria and phosphorylates FUNDC1 to regulate mitophagy. EMBO Rep. 2014, 15(5):566-575.
    • (2014) EMBO Rep. , vol.15 , Issue.5 , pp. 566-575
    • Wu, W.1
  • 113
    • 84873867668 scopus 로고    scopus 로고
    • Coordinate autophagy and mTOR pathway inhibition enhances cell death in melanoma
    • Xie X., White E.P., Mehnert J.M. Coordinate autophagy and mTOR pathway inhibition enhances cell death in melanoma. PLoS One 2013, 8(1):e55096.
    • (2013) PLoS One , vol.8 , Issue.1 , pp. e55096
    • Xie, X.1    White, E.P.2    Mehnert, J.M.3
  • 114
    • 84887453820 scopus 로고    scopus 로고
    • PINK1 is degraded through the N-end rule pathway
    • Yamano K., Youle R.J. PINK1 is degraded through the N-end rule pathway. Autophagy 2013, 9(11):1758-1769.
    • (2013) Autophagy , vol.9 , Issue.11 , pp. 1758-1769
    • Yamano, K.1    Youle, R.J.2
  • 115
    • 84898652320 scopus 로고    scopus 로고
    • Mitochondrial Rab GAPs govern autophagosome biogenesis during mitophagy
    • Yamano K., et al. Mitochondrial Rab GAPs govern autophagosome biogenesis during mitophagy. Elife 2014, 3:e01612.
    • (2014) Elife , vol.3 , pp. e01612
    • Yamano, K.1
  • 116
    • 79952229430 scopus 로고    scopus 로고
    • Pancreatic cancers require autophagy for tumor growth
    • Yang S., et al. Pancreatic cancers require autophagy for tumor growth. Genes Dev. 2011, 25(7):717-729.
    • (2011) Genes Dev. , vol.25 , Issue.7 , pp. 717-729
    • Yang, S.1
  • 118
    • 84885430184 scopus 로고    scopus 로고
    • Induction of neuronal mitophagy in acute spinal cord injury in rats
    • Yu D., et al. Induction of neuronal mitophagy in acute spinal cord injury in rats. Neurotox. Res. 2013, 24(4):512-522.
    • (2013) Neurotox. Res. , vol.24 , Issue.4 , pp. 512-522
    • Yu, D.1
  • 119
    • 79955600341 scopus 로고    scopus 로고
    • Mitophagy and mitochondrial morphology in human melanoma-derived cells post exposure to simulated sunlight
    • Zanchetta L.M., et al. Mitophagy and mitochondrial morphology in human melanoma-derived cells post exposure to simulated sunlight. Int. J. Radiat. Biol. 2011, 87(5):506-517.
    • (2011) Int. J. Radiat. Biol. , vol.87 , Issue.5 , pp. 506-517
    • Zanchetta, L.M.1
  • 120
    • 84878897444 scopus 로고    scopus 로고
    • Biology and trafficking of ATG9 and ATG16L1, two proteins that regulate autophagosome formation
    • Zavodszky E., Vicinanza M., Rubinsztein D.C. Biology and trafficking of ATG9 and ATG16L1, two proteins that regulate autophagosome formation. FEBS Lett. 2013, 587(13):1988-1996.
    • (2013) FEBS Lett. , vol.587 , Issue.13 , pp. 1988-1996
    • Zavodszky, E.1    Vicinanza, M.2    Rubinsztein, D.C.3
  • 121
    • 67549101188 scopus 로고    scopus 로고
    • Role of BNIP3 and NIX in cell death, autophagy, and mitophagy
    • Zhang J., Ney P.A. Role of BNIP3 and NIX in cell death, autophagy, and mitophagy. Cell Death Differ. 2009, 16(7):939-946.
    • (2009) Cell Death Differ. , vol.16 , Issue.7 , pp. 939-946
    • Zhang, J.1    Ney, P.A.2
  • 122
    • 70349668309 scopus 로고    scopus 로고
    • BNIP3 mediates cell death by different pathways following localization to endoplasmic reticulum and mitochondrion
    • Zhang L., et al. BNIP3 mediates cell death by different pathways following localization to endoplasmic reticulum and mitochondrion. FASEB J. 2009, 23(10):3405-3414.
    • (2009) FASEB J. , vol.23 , Issue.10 , pp. 3405-3414
    • Zhang, L.1
  • 123
    • 84872291490 scopus 로고    scopus 로고
    • Modulation of serines 17 and 24 in the LC3-interacting region of Bnip3 determines pro-survival mitophagy versus apoptosis
    • Zhu Y., et al. Modulation of serines 17 and 24 in the LC3-interacting region of Bnip3 determines pro-survival mitophagy versus apoptosis. J. Biol. Chem. 2013, 288(2):1099-1113.
    • (2013) J. Biol. Chem. , vol.288 , Issue.2 , pp. 1099-1113
    • Zhu, Y.1
  • 124
    • 77950384477 scopus 로고    scopus 로고
    • Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin
    • Ziviani E., Tao R.N., Whitworth A.J. Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin. Proc. Natl. Acad. Sci. U. S. A. 2010, 107(11):5018-5023.
    • (2010) Proc. Natl. Acad. Sci. U. S. A. , vol.107 , Issue.11 , pp. 5018-5023
    • Ziviani, E.1    Tao, R.N.2    Whitworth, A.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.