메뉴 건너뛰기




Volumn 18, Issue 2, 2012, Pages 370-379

Punctate LC3B expression is a common feature of solid tumors and associated with proliferation, metastasis, and poor outcome

Author keywords

[No Author keywords available]

Indexed keywords

KI 67 ANTIGEN; MICROTUBULE ASSOCIATED PROTEIN 1; MICROTUBULE ASSOCIATED PROTEIN 1 LIGHT CHAIN 3; UNCLASSIFIED DRUG;

EID: 84856003912     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-11-1282     Document Type: Article
Times cited : (265)

References (31)
  • 2
    • 77956172813 scopus 로고    scopus 로고
    • Physiological role of autophagy as an intracellular recycling system: With an emphasis on nutrient metabolism
    • Kuma A, Mizushima N. Physiological role of autophagy as an intracellular recycling system: with an emphasis on nutrient metabolism. Semin Cell Dev Biol 2010;21:683-90.
    • (2010) Semin Cell Dev Biol , vol.21 , pp. 683-690
    • Kuma, A.1    Mizushima, N.2
  • 5
    • 37549056216 scopus 로고    scopus 로고
    • The roles of therapy-induced autophagy and necrosis in cancer treatment
    • Amaravadi RK, Thompson CB. The roles of therapy-induced autophagy and necrosis in cancer treatment. Clin Cancer Res 2007;13:7271-9.
    • (2007) Clin Cancer Res , vol.13 , pp. 7271-7279
    • Amaravadi, R.K.1    Thompson, C.B.2
  • 7
    • 79961116194 scopus 로고    scopus 로고
    • A critical role for autophagy in pancreatic cancer
    • Yang S, Kimmelman AC. A critical role for autophagy in pancreatic cancer. Autophagy 2011;7:912-3.
    • (2011) Autophagy , vol.7 , pp. 912-913
    • Yang, S.1    Kimmelman, A.C.2
  • 9
    • 79952228407 scopus 로고    scopus 로고
    • Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis
    • Guo JY, Chen HY, Mathew R, Fan J, Strohecker AM, Karsli-Uzunbas G, et al. Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis. Genes Dev 2011;25:460-70.
    • (2011) Genes Dev , vol.25 , pp. 460-470
    • Guo, J.Y.1    Chen, H.Y.2    Mathew, R.3    Fan, J.4    Strohecker, A.M.5    Karsli-Uzunbas, G.6
  • 10
    • 66449122303 scopus 로고    scopus 로고
    • Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells
    • Bellodi C, Lidonnici MR, Hamilton A, Helgason GV, Soliera AR, Ronchetti M, et al. Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells. J Clin Invest 2009;119:1109-23.
    • (2009) J Clin Invest , vol.119 , pp. 1109-1123
    • Bellodi, C.1    Lidonnici, M.R.2    Hamilton, A.3    Helgason, G.V.4    Soliera, A.R.5    Ronchetti, M.6
  • 11
    • 53749104349 scopus 로고    scopus 로고
    • Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents
    • Degtyarev M, De Mazière A, Orr C, Lin J, Lee BB, Tien JY, et al. Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents. J Cell Biol 2008;183:101-16.
    • (2008) J Cell Biol , vol.183 , pp. 101-116
    • Degtyarev, M.1    De Mazière, A.2    Orr, C.3    Lin, J.4    Lee, B.B.5    Tien, J.Y.6
  • 12
    • 34347394714 scopus 로고    scopus 로고
    • Targeting autophagy augments the anticancer activity of the histone deacetylase inhibitor SAHAto overcome Bcr-Abl-mediated drug resistance
    • DOI 10.1182/blood-2006-10-050260
    • Carew JS, Nawrocki ST, Kahue CN, Zhang H, Yang C, Chung L, et al. Targeting autophagy augments the anticancer activity of the histone deacetylase inhibitorSAHA to overcome Bcr-Abl-mediated drug resistance. Blood 2007;110:313-22. (Pubitemid 47026849)
    • (2007) Blood , vol.110 , Issue.1 , pp. 313-322
    • Carew, J.S.1    Nawrocki, S.T.2    Kahue, C.N.3    Zhang, H.4    Yang, C.5    Chung, L.6    Houghton, J.A.7    Huang, P.8    Giles, F.J.9    Cleveland, J.L.10
  • 13
    • 67651155954 scopus 로고    scopus 로고
    • Oncogenic transformation confers a selective susceptibility to the combined suppression of the proteasome and autophagy
    • Ding WX, Ni HM, Gao W, Chen X, Kang JH, Stolz DB, et al. Oncogenic transformation confers a selective susceptibility to the combined suppression of the proteasome and autophagy. Mol Cancer Ther 2009;8:2036-45.
    • (2009) Mol Cancer Ther , vol.8 , pp. 2036-2045
    • Ding, W.X.1    Ni, H.M.2    Gao, W.3    Chen, X.4    Kang, J.H.5    Stolz, D.B.6
  • 14
    • 33847008972 scopus 로고    scopus 로고
    • DNA damaging agent-induced autophagy produces a cytoprotective adenosine triphosphate surge in malignant glioma cells
    • Katayama M, Kawaguchi T, Berger MS, Pieper RO. DNA damaging agent-induced autophagy produces a cytoprotective adenosine triphosphate surge in malignant glioma cells. Cell Death Differ 2007;14:548-58.
    • (2007) Cell Death Differ , vol.14 , pp. 548-558
    • Katayama, M.1    Kawaguchi, T.2    Berger, M.S.3    Pieper, R.O.4
  • 15
    • 9244229046 scopus 로고    scopus 로고
    • Automated quantitative analysis of tissue microarrays reveals an association between high Bcl-2 expression and improved outcome in melanoma
    • DOI 10.1158/0008-5472.CAN-04-1387
    • Divito KA, Berger AJ, CampRL, Dolled-Filhart M,Rimm DL, Kluger HM. Automated quantitative analysis of tissue microarrays reveals an association between high Bcl-2 expression and improved outcome in melanoma. Cancer Res 2004;64:8773-7. (Pubitemid 39552096)
    • (2004) Cancer Research , vol.64 , Issue.23 , pp. 8773-8777
    • DiVito, K.A.1    Berger, A.J.2    Camp, R.L.3    Dolled-Filhart, M.4    Rimm, D.L.5    Kluger, H.M.6
  • 16
    • 9244241036 scopus 로고    scopus 로고
    • Automated quantitative analysis of HDM2 expression in malignant melanoma shows association with early-stage disease and improved outcome
    • DOI 10.1158/0008-5472.CAN-04-1384
    • Berger AJ, Camp RL, Divito KA, Kluger HM, Halaban R, Rimm DL. Automated quantitative analysis of HDM2 expression in malignant melanoma shows association with early-stage disease and improved outcome. Cancer Res 2004;64:8767-72. (Pubitemid 39552095)
    • (2004) Cancer Research , vol.64 , Issue.23 , pp. 8767-8772
    • Berger, A.J.1    Camp, R.L.2    DiVito, K.A.3    Kluger, H.M.4    Halaban, R.5    Rimm, D.L.6
  • 17
    • 0036852721 scopus 로고    scopus 로고
    • Automated subcellular localization and quantification of protein expression in tissue microarrays
    • DOI 10.1038/nm791
    • Camp RL, Chung GG, Rimm DL. Automated subcellular localization and quantification of protein expression in tissue microarrays. Nat Med 2002;8:1323-7. (Pubitemid 35373567)
    • (2002) Nature Medicine , vol.8 , Issue.11 , pp. 1323-1327
    • Camp, R.L.1    Chung, G.G.2    Rimm, D.L.3
  • 18
    • 0034329418 scopus 로고    scopus 로고
    • LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
    • Kabeya Y, Mizushima N, Ueno T, Yamamoto A, Kirisako T, Noda T, et al. LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J 2000;19:5720-8.
    • (2000) EMBO J , vol.19 , pp. 5720-5728
    • Kabeya, Y.1    Mizushima, N.2    Ueno, T.3    Yamamoto, A.4    Kirisako, T.5    Noda, T.6
  • 19
    • 38949108670 scopus 로고    scopus 로고
    • Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
    • Klionsky DJ, Abeliovich H, Agostinis P, Agrawal DK, Aliev G, Askew DS, et al. Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy 2008;4:151-75.
    • (2008) Autophagy , vol.4 , Issue.2 , pp. 151-175
    • Klionsky, D.J.1    Abeliovich, H.2    Agostinis, P.3    Agrawal, D.K.4    Aliev, G.5    Askew, D.S.6
  • 20
    • 78650328444 scopus 로고    scopus 로고
    • Autophagy basics
    • Tanida I. Autophagy basics. Microbiol Immunol 2011;55:1-11.
    • (2011) Microbiol Immunol , vol.55 , pp. 1-11
    • Tanida, I.1
  • 21
    • 79951650004 scopus 로고    scopus 로고
    • Measurement of autophagy in cells and tissues
    • Tanida I, Waguri S. Measurement of autophagy in cells and tissues. Methods Mol Biol 2010;648:193-214.
    • (2010) Methods Mol Biol , vol.648 , pp. 193-214
    • Tanida, I.1    Waguri, S.2
  • 22
    • 74049101149 scopus 로고    scopus 로고
    • Autophagy in cutaneous malignant melanoma
    • Lazova R, Klump V, Pawelek J. Autophagy in cutaneous malignant melanoma. J Cutan Pathol 2010;37:256-68.
    • (2010) J Cutan Pathol , vol.37 , pp. 256-268
    • Lazova, R.1    Klump, V.2    Pawelek, J.3
  • 23
    • 33744938180 scopus 로고    scopus 로고
    • Quantitative in situ analysis of beta-catenin expression in breast cancer shows decreased expression is associated with poor outcome
    • DOI 10.1158/0008-5472.CAN-06-0100
    • Dolled-Filhart M, McCabe A, Giltnane J, Cregger M, Camp RL, Rimm DL. Quantitative in situ analysis of beta-catenin expression in breast cancer shows decreased expression is associated with poor outcome. Cancer Res 2006;66:5487-94. (Pubitemid 43844977)
    • (2006) Cancer Research , vol.66 , Issue.10 , pp. 5487-5494
    • Dolled-Filhart, M.1    McCabe, A.2    Giltnane, J.3    Cregger, M.4    Camp, R.L.5    Rimm, D.L.6
  • 24
    • 79956003662 scopus 로고    scopus 로고
    • Measurements of tumor cell autophagy predict invasiveness, resistance to chemotherapy, and survival in melanoma
    • Ma XH, Piao S, Wang D, McAfee QW, Nathanson KL, Lum JJ, et al. Measurements of tumor cell autophagy predict invasiveness, resistance to chemotherapy, and survival in melanoma. Clin Cancer Res 2011;17:3478-89.
    • (2011) Clin Cancer Res , vol.17 , pp. 3478-3489
    • Ma, X.H.1    Piao, S.2    Wang, D.3    McAfee, Q.W.4    Nathanson, K.L.5    Lum, J.J.6
  • 26
    • 80052382924 scopus 로고    scopus 로고
    • The protective role of autophagy against aging and acute ischemic injury in kidney proximal tubular cells
    • Isaka Y, Kimura T, Takabatake Y. The protective role of autophagy against aging and acute ischemic injury in kidney proximal tubular cells. Autophagy 2011;7:1085-7.
    • (2011) Autophagy , vol.7 , pp. 1085-1087
    • Isaka, Y.1    Kimura, T.2    Takabatake, Y.3
  • 27
    • 79958167078 scopus 로고    scopus 로고
    • Functions of autophagy in hepatic and pancreatic physiology and disease
    • Czaja MJ. Functions of autophagy in hepatic and pancreatic physiology and disease. Gastroenterology 2011;140:1895-908.
    • (2011) Gastroenterology , vol.140 , pp. 1895-1908
    • Czaja, M.J.1
  • 28
    • 33745713171 scopus 로고    scopus 로고
    • Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis
    • Degenhardt K, Mathew R, Beaudoin B, Bray K, Anderson D, Chen G, et al. Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis. Cancer Cell 2006;10:51-64.
    • (2006) Cancer Cell , vol.10 , pp. 51-64
    • Degenhardt, K.1    Mathew, R.2    Beaudoin, B.3    Bray, K.4    Anderson, D.5    Chen, G.6
  • 29
    • 35448980704 scopus 로고    scopus 로고
    • Autophagy is activated in colorectal cancer cells and contributes to the tolerance to nutrient deprivation
    • DOI 10.1158/0008-5472.CAN-07-1462
    • Sato K, Tsuchihara K, Fujii S, Sugiyama M, Goya T, Atomi Y, et al. Autophagy is activated in colorectal cancer cells and contributes to the tolerance to nutrient deprivation. Cancer Res 2007;67:9677-84. (Pubitemid 47621214)
    • (2007) Cancer Research , vol.67 , Issue.20 , pp. 9677-9684
    • Sato, K.1    Tsuchihara, K.2    Fujii, S.3    Sugiyama, M.4    Goya, T.5    Atomi, Y.6    Ueno, T.7    Ochiai, A.8    Esumi, H.9
  • 30
    • 54849188100 scopus 로고    scopus 로고
    • LC3, an autophagosome marker, is highly expressed in gastrointestinal cancers
    • Yoshioka A, Miyata H, Doki Y, Yamasaki M, Sohma I, Gotoh K, et al. LC3, an autophagosome marker, is highly expressed in gastrointestinal cancers. Int J Oncol 2008;33:461-8.
    • (2008) Int J Oncol , vol.33 , pp. 461-468
    • Yoshioka, A.1    Miyata, H.2    Doki, Y.3    Yamasaki, M.4    Sohma, I.5    Gotoh, K.6
  • 31
    • 50149095124 scopus 로고    scopus 로고
    • Autophagy is activated in pancreatic cancer cells and correlates with poor patient outcome
    • Fujii S, Mitsunaga S, Yamazaki M, Hasebe T, Ishii G, Kojima M, et al. Autophagy is activated in pancreatic cancer cells and correlates with poor patient outcome. Cancer Sci 2008;99:1813-9.
    • (2008) Cancer Sci , vol.99 , pp. 1813-1819
    • Fujii, S.1    Mitsunaga, S.2    Yamazaki, M.3    Hasebe, T.4    Ishii, G.5    Kojima, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.