Overexpression of autophagy-related beclin-1 in advanced malignant melanoma and its low expression in melanoma-in-situ

European Journal of Dermatology

Volumn 22, Issue 1, 2012, Pages 128-129

  Hara, Yoko ^a   Nakamura, Motonobu ^a  

^a Occupational and Environmental Health ^*  (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BECLIN 1;

AGED; ARTICLE; AUTOPHAGY; CASE REPORT; CELL PROLIFERATION; FEMALE; GENE OVEREXPRESSION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INGUINAL LYMPH NODE; MELANOMA; PROTEIN EXPRESSION; SENTINEL LYMPH NODE BIOPSY; TUMOR LOCALIZATION; TUMOR VOLUME;

AGED; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LYMPHATIC METASTASIS; MELANOMA; MEMBRANE PROTEINS; MIDDLE AGED; SKIN NEOPLASMS;

EID: 84857885730     PISSN: 11671122     EISSN: 19524013     Source Type: Journal    
DOI: 10.1684/ejd.2011.1562     Document Type: Article

References (6)

1. Sivridis E, Koukourakis MI, Mendrinos SE, et al. Beclin-1 and LC3A expression in cutaneous malignant melanomas: a biphasic survival pattern for beclin-1. Melanoma Res 2011; 21: 188-195.
2. Lazova R, Klump V, Pawelek J. Autophagy in cutaneous malignant melnoma. J Cutan Pathol 2010; 37: 256-268.
3. Miracco C, Cevenini G, Franchi A, et al. Beclin 1 and LC3 autophagic gene expression in cutaneous melanocytic lesions. Hum Pathol 2010; 41: 503-512.
4. Okura R, Nakamura M. Overexpression of autophagy-related beclin-1 in cutaneous squamous cell carcinoma with lymph-node metastasis. Eur J Dermatol 2011; 21 (in press).
5. Armstrong JL, Corazzari M, Martin S, et al. Oncogenic B-RAF signaling in melanoma impairs the therapeutic advantage of autophagy inhibition. Clin Cancer Res 2011; 17: 2216-2226.
6. Lee SJ, Kim HP, Jin Y, et al. Beclin 1 deficiency is associated with increased hypoxia-induced angiogenesis. Autophagy 2011;7:829-839