-
1
-
-
0034077041
-
Mice lacking α-synuclein display functional deficits in the nigrostriatal dopamine system
-
Abeliovich, A.; Schmitz, Y.; Farinas, I.; Choi-Lundberg, D.; Ho, W. H.; Castillo, P. E.; Shinsky, N.; Verdugo, J. M.; Armanini, M.; Ryan, A.; Hynes, M.; Phillips, H.; Sulzer, D.; Rosenthal, A. Mice lacking α-synuclein display functional deficits in the nigrostriatal dopamine system. Neuron 25(1):239-252; 2000.
-
(2000)
Neuron
, vol.25
, Issue.1
, pp. 239-252
-
-
Abeliovich, A.1
Schmitz, Y.2
Farinas, I.3
Choi-Lundberg, D.4
Ho, W.H.5
Castillo, P.E.6
Shinsky, N.7
Verdugo, J.M.8
Armanini, M.9
Ryan, A.10
Hynes, M.11
Phillips, H.12
Sulzer, D.13
Rosenthal, A.14
-
2
-
-
7444237665
-
Mutations in the glucocerebrosidase gene and Parkinson's disease in Ashkenazi Jews
-
Aharon-Peretz, J.; Rosenbaum, H.; Gershoni-Baruch, R. Mutations in the glucocerebrosidase gene and Parkinson's disease in Ashkenazi Jews. N. Engl. J. Med. 351(19):1972-1977; 2004.96
-
(2004)
N. Engl. J. Med
, vol.351
, Issue.19
, pp. 1972-1977
-
-
Aharon-Peretz, J.1
Rosenbaum, H.2
Gershoni-Baruch, R.3
-
3
-
-
33749570292
-
Phosphorylation of Ser-129 is the dominant pathological modification of α-synuclein in familial and sporadic Lewy body disease
-
Anderson, J. P.; Walker, D. E.; Goldstein, J. M.; de Laat, R.; Banducci, K.; Caccavello, R. J.; Barbour, R.; Huang, J.; Kling, K.; Lee, M.; Diep, L.; Keim, P. S.; Shen, X.; Chataway, T.; Schlossmacher, M. G.; Seubert, P.; Schenk, D.; Sinha, S.; Gai, W. P.; Chilcote, T. J. Phosphorylation of Ser-129 is the dominant pathological modification of α-synuclein in familial and sporadic Lewy body disease. J. Biol. Chem. 281(40):29739-29752; 2006.
-
(2006)
J. Biol. Chem
, vol.281
, Issue.40
, pp. 29739-29752
-
-
Anderson, J.P.1
Walker, D.E.2
Goldstein, J.M.3
de Laat, R.4
Banducci, K.5
Caccavello, R.J.6
Barbour, R.7
Huang, J.8
Kling, K.9
Lee, M.10
Diep, L.11
Keim, P.S.12
Shen, X.13
Chataway, T.14
Schlossmacher, M.G.15
Seubert, P.16
Schenk, D.17
Sinha, S.18
Gai, W.P.19
Chilcote, T.J.20
more..
-
4
-
-
0141705319
-
Highly regionalized distribution of stromal cell-derived factor-1/CXCL12 in adult rat brain: Constitutive expression in cholinergic, dopaminergic and vasopressinergic neurons
-
Banisadr, G.; Skrzydelski, D.; Kitabgi, P.; Rostene, W.; Parsadaniantz, S. M. Highly regionalized distribution of stromal cell-derived factor-1/CXCL12 in adult rat brain: Constitutive expression in cholinergic, dopaminergic and vasopressinergic neurons. Eur. J. Neurosci. 18(6):1593-1606; 2003.
-
(2003)
Eur. J. Neurosci
, vol.18
, Issue.6
, pp. 1593-1606
-
-
Banisadr, G.1
Skrzydelski, D.2
Kitabgi, P.3
Rostene, W.4
Parsadaniantz, S.M.5
-
5
-
-
10744229091
-
Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice
-
Barberi, T.; Klivenyi, P.; Calingasan, N. Y.; Lee, H.; Kawamata, H.; Loonam, K.; Perrier, A. L.; Bruses, J.; Rubio, M. E.; Topf, N.; Tabar, V.; Harrison, N. L.; Beal, M. F.; Moore, M. A.; Studer, L. Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice. Nat. Biotechnol. 21(10):1200-1207; 2003.
-
(2003)
Nat. Biotechnol
, vol.21
, Issue.10
, pp. 1200-1207
-
-
Barberi, T.1
Klivenyi, P.2
Calingasan, N.Y.3
Lee, H.4
Kawamata, H.5
Loonam, K.6
Perrier, A.L.7
Bruses, J.8
Rubio, M.E.9
Topf, N.10
Tabar, V.11
Harrison, N.L.12
Beal, M.F.13
Moore, M.A.14
Studer, L.15
-
6
-
-
78649788364
-
LRRK2 G2019S mutation in Parkinson's disease: A neuropsychological and neuropsychiatric study in a large Algerian cohort
-
Belarbi, S.; Hecham, N.; Lesage, S.; Kediha, M. I.; Smail, N.; Benhassine, T.; Ysmail-Dahlouk, F.; Lohman, E.; Benhabyles, B.; Hamadouche, T.; Assami, S.; Brice, A.; Tazir, M. LRRK2 G2019S mutation in Parkinson's disease: A neuropsychological and neuropsychiatric study in a large Algerian cohort. Parkinsonism Relat. Disord. 16(10):676-679; 2010.
-
(2010)
Parkinsonism Relat. Disord
, vol.16
, Issue.10
, pp. 676-679
-
-
Belarbi, S.1
Hecham, N.2
Lesage, S.3
Kediha, M.I.4
Smail, N.5
Benhassine, T.6
Ysmail-Dahlouk, F.7
Lohman, E.8
Benhabyles, B.9
Hamadouche, T.10
Assami, S.11
Brice, A.12
Tazir, M.13
-
7
-
-
33646375711
-
High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease
-
Bender, A.; Krishnan, K. J.; Morris, C. M.; Taylor, G. A.; Reeve, A. K.; Perry, R. H.; Jaros, E.; Hersheson, J. S.; Betts, J.; Klopstock, T.; Taylor, R. W.; Turnbull, D. M. High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease. Nat. Genet. 38(5):515-517; 2006.
-
(2006)
Nat. Genet
, vol.38
, Issue.5
, pp. 515-517
-
-
Bender, A.1
Krishnan, K.J.2
Morris, C.M.3
Taylor, G.A.4
Reeve, A.K.5
Perry, R.H.6
Jaros, E.7
Hersheson, J.S.8
Betts, J.9
Klopstock, T.10
Taylor, R.W.11
Turnbull, D.M.12
-
8
-
-
0015745743
-
Brain dopamine and the syndromes of Parkinson and Huntington. Clinical, morphological and neurochemical correlations
-
Bernheimer, H.; Birkmayer, W.; Hornykiewicz, O.; Jellinger, K.; Seitelberger, F. Brain dopamine and the syndromes of Parkinson and Huntington. Clinical, morphological and neurochemical correlations. J. Neurol. Sci. 20(4):415-455; 1973.
-
(1973)
J. Neurol. Sci
, vol.20
, Issue.4
, pp. 415-455
-
-
Bernheimer, H.1
Birkmayer, W.2
Hornykiewicz, O.3
Jellinger, K.4
Seitelberger, F.5
-
9
-
-
0034032642
-
Cell replacement therapies for central nervous system disorders
-
Bjorklund, A.; Lindvall, O. Cell replacement therapies for central nervous system disorders. Nat. Neurosci. 3(6):537-544; 2000.
-
(2000)
Nat. Neurosci
, vol.3
, Issue.6
, pp. 537-544
-
-
Bjorklund, A.1
Lindvall, O.2
-
10
-
-
0018743999
-
Regeneration of monoaminergic and cholinergic neurons in the mammalian central nervous system
-
Bjorklund, A.; Stenevi, U. Regeneration of monoaminergic and cholinergic neurons in the mammalian central nervous system. Physiol. Rev. 59(1):62-100; 1979.
-
(1979)
Physiol. Rev
, vol.59
, Issue.1
, pp. 62-100
-
-
Bjorklund, A.1
Stenevi, U.2
-
11
-
-
0017119186
-
Growth of transplanted monoaminergic neurones into the adult hippocampus along the perforant path
-
Bjorklund, A.; Stenevi, U.; Svendgaard, N. Growth of transplanted monoaminergic neurones into the adult hippocampus along the perforant path. Nature 262(5571):787-790; 1976.
-
(1976)
Nature
, vol.262
, Issue.5571
, pp. 787-790
-
-
Bjorklund, A.1
Stenevi, U.2
Svendgaard, N.3
-
12
-
-
22044432781
-
Early-onset parkinsonism associated with PINK1 mutations
-
Bonifati, V.; Rohe, C. F.; Breedveld, G. J.; Fabrizio, E.; De Mari, M.; Tassorelli, C.; Tavella, A.; Marconi, R.; Nicholl, D. J.; Chien, H. F.; Fincati, E.; Abbruzzese, G.; Marini, P.; De Gaetano, A.; Horstink, M. W.; Maat-Kievit, J. A.; Sampaio, C.; Antonini, A.; Stocchi, F.; Montagna, P.; Toni, V.; Guidi, M.; Dalla Libera, A.; Tinazzi, M.; De Pandis, F.; Fabbrini, G.; Goldwurm, S.; de Klein, A.; Barbosa, E.; Lopiano, L.; Martignoni, E.; Lamberti, P.; Vanacore, N.; Meco, G.; Oostra, B. A. Early-onset parkinsonism associated with PINK1 mutations: Frequency, genotypes, and phenotypes. Neurology 65(1):87-95; 2005.
-
(2005)
Frequency, Genotypes, and Phenotypes. Neurology
, vol.65
, Issue.1
, pp. 87-95
-
-
Bonifati, V.1
Rohe, C.F.2
Breedveld, G.J.3
Fabrizio, E.4
de Mari, M.5
Tassorelli, C.6
Tavella, A.7
Marconi, R.8
Nicholl, D.J.9
Chien, H.F.10
Fincati, E.11
Abbruzzese, G.12
Marini, P.13
de Gaetano, A.14
Horstink, M.W.15
Maat-Kievit, J.A.16
Sampaio, C.17
Antonini, A.18
Stocchi, F.19
Montagna, P.20
Toni, V.21
Guidi, M.22
Dalla, L.A.23
Tinazzi, M.24
de Pandis, F.25
Fabbrini, G.26
Goldwurm, S.27
de Klein, A.28
Barbosa, E.29
Lopiano, L.30
Martignoni, E.31
Lamberti, P.32
Vanacore, N.33
Meco, G.34
Oostra, B.A.35
more..
-
13
-
-
77952708547
-
Ubiquitin vinyl methyl ester binding orients the misaligned active site of the ubiquitin hydrolase UCHL1 into productive conformation
-
Boudreaux, D. A.; Maiti, T. K.; Davies, C. W.; Das, C. Ubiquitin vinyl methyl ester binding orients the misaligned active site of the ubiquitin hydrolase UCHL1 into productive conformation. Proc. Natl. Acad. Sci. USA 107(20):9117-9122; 2010.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, Issue.20
, pp. 9117-9122
-
-
Boudreaux, D.A.1
Maiti, T.K.2
Davies, C.W.3
Das, C.4
-
14
-
-
34447629079
-
Interactions between metals and α-synuclein- function or artefact?
-
Brown, D. R. Interactions between metals and α-synuclein- function or artefact? FEBS J. 274(15):3766-3774; 2007.
-
(2007)
FEBS J
, vol.274
, Issue.15
, pp. 3766-3774
-
-
Brown, D.R.1
-
15
-
-
60349093075
-
Metal binding to α-synuclein peptides and its contribution to toxicity
-
Brown, D. R. Metal binding to α-synuclein peptides and its contribution to toxicity. Biochem. Biophys. Res. Commun. 380(2):377-381; 2009.
-
(2009)
Biochem. Biophys. Res. Commun
, vol.380
, Issue.2
, pp. 377-381
-
-
Brown, D.R.1
-
16
-
-
0034065380
-
Improving the survival of grafted dopaminergic neurons: A review over current approaches
-
Brundin, P.; Karlsson, J.; Emgard, M.; Schierle, G. S.; Hansson, O.; Petersen, A.; Castilho, R. F. Improving the survival of grafted dopaminergic neurons: A review over current approaches. Cell Transplant. 9(2):179-195; 2000.
-
(2000)
Cell Transplant
, vol.9
, Issue.2
, pp. 179-195
-
-
Brundin, P.1
Karlsson, J.2
Emgard, M.3
Schierle, G.S.4
Hansson, O.5
Petersen, A.6
Castilho, R.F.7
-
17
-
-
0037418936
-
Intravenous administration of human bone marrow stromal cells induces angiogenesis in the ischemic boundary zone after stroke in rats
-
Chen, J.; Zhang, Z. G.; Li, Y.; Wang, L.; Xu, Y. X.; Gautam, S. C.; Lu, M.; Zhu, Z.; Chopp, M. Intravenous administration of human bone marrow stromal cells induces angiogenesis in the ischemic boundary zone after stroke in rats. Circ. Res. 92(6):692-699; 2003.
-
(2003)
Circ. Res
, vol.92
, Issue.6
, pp. 692-699
-
-
Chen, J.1
Zhang, Z.G.2
Li, Y.3
Wang, L.4
Xu, Y.X.5
Gautam, S.C.6
Lu, M.7
Zhu, Z.8
Chopp, M.9
-
18
-
-
0035856443
-
Prevalence, incidence, and mortality of PD: A door-to-door survey in Ilan county, Taiwan
-
Chen, R. C.; Chang, S. F.; Su, C. L.; Chen, T. H.; Yen, M. F.; Wu, H. M.; Chen, Z. Y.; Liou, H. H. Prevalence, incidence, and mortality of PD: A door-to-door survey in Ilan county, Taiwan. Neurology 57(9):1679-1686; 2001.
-
(2001)
Neurology
, vol.57
, Issue.9
, pp. 1679-1686
-
-
Chen, R.C.1
Chang, S.F.2
Su, C.L.3
Chen, T.H.4
Yen, M.F.5
Wu, H.M.6
Chen, Z.Y.7
Liou, H.H.8
-
19
-
-
52649085337
-
Neurally induced umbilical cord blood cells modestly repair injured spinal cords
-
Cho, S. R.; Yang, M. S.; Yim, S. H.; Park, J. H.; Lee, J. E.; Eom, Y. W.; Jang, I. K.; Kim, H. E.; Park, J. S.; Kim, H. O.; Lee, B. H.; Park, C. I.; Kim, Y. J. Neurally induced umbilical cord blood cells modestly repair injured spinal cords. Neuroreport 19(13):1259-1263; 2008.
-
(2008)
Neuroreport
, vol.19
, Issue.13
, pp. 1259-1263
-
-
Cho, S.R.1
Yang, M.S.2
Yim, S.H.3
Park, J.H.4
Lee, J.E.5
Eom, Y.W.6
Jang, I.K.7
Kim, H.E.8
Park, J.S.9
Kim, H.O.10
Lee, B.H.11
Park, C.I.12
Kim, Y.J.13
-
20
-
-
33749242798
-
Induction of dopaminergic neurons from growth factor expanded neural stem/progenitor cell cultures derived from human first trimester forebrain
-
Christophersen, N. S.; Meijer, X.; Jorgensen, J. R.; Englund, U.; Gronborg, M.; Seiger, A.; Brundin, P.; Wahlberg, L. U. Induction of dopaminergic neurons from growth factor expanded neural stem/progenitor cell cultures derived from human first trimester forebrain. Brain Res. Bull. 70(4-6): 457-466; 2006.
-
(2006)
Brain Res. Bull
, vol.70
, Issue.4-6
, pp. 457-466
-
-
Christophersen, N.S.1
Meijer, X.2
Jorgensen, J.R.3
Englund, U.4
Gronborg, M.5
Seiger, A.6
Brundin, P.7
Wahlberg, L.U.8
-
21
-
-
77949906891
-
Lewy body pathology in fetal grafts
-
Chu, Y.; Kordower, J. H. Lewy body pathology in fetal grafts. Ann. N. Y. Acad. Sci. 1184:55-67; 2010.
-
(2010)
Ann. N. Y. Acad. Sci
, vol.1184
, pp. 55-67
-
-
Chu, Y.1
Kordower, J.H.2
-
22
-
-
0032102455
-
The synucleins: A family of proteins involved in synaptic function, plasticity, neurodegene- ration and disease
-
Clayton, D. F.; George, J. M. The synucleins: A family of proteins involved in synaptic function, plasticity, neurodegene- ration and disease. Trends Neurosci. 21(6):249-254; 1998.
-
(1998)
Trends Neurosci
, vol.21
, Issue.6
, pp. 249-254
-
-
Clayton, D.F.1
George, J.M.2
-
23
-
-
44749085250
-
Mitochondrial translocation of α-synuclein is promoted by intracellular acidification
-
Cole, N. B.; Dieuliis, D.; Leo, P.; Mitchell, D. C.; Nussbaum, R. L. Mitochondrial translocation of α-synuclein is promoted by intracellular acidification. Exp. Cell Res. 314(10):2076-2089; 2008.
-
(2008)
Exp. Cell Res
, vol.314
, Issue.10
, pp. 2076-2089
-
-
Cole, N.B.1
Dieuliis, D.2
Leo, P.3
Mitchell, D.C.4
Nussbaum, R.L.5
-
24
-
-
33746533924
-
Lindquist, S. α-Synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models
-
Cooper, A. A.; Gitler, A. D.; Cashikar, A.; Haynes, C. M.; Hill, K. J.; Bhullar, B.; Liu, K.; Xu, K.; Strathearn, K. E.; Liu, F.; Cao, S.; Caldwell, K. A.; Caldwell, G. A.; Marsischky, G.; Kolodner, R. D.; Labaer, J.; Rochet, J. C.; Bonini, N. M.; Lindquist, S. α-Synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models. Science 313(5785):324-328; 2006.
-
(2006)
Science
, vol.313
, Issue.5785
, pp. 324-328
-
-
Cooper, A.A.1
Gitler, A.D.2
Cashikar, A.3
Haynes, C.M.4
Hill, K.J.5
Bhullar, B.6
Liu, K.7
Xu, K.8
Strathearn, K.E.9
Liu, F.10
Cao, S.11
Caldwell, K.A.12
Caldwell, G.A.13
Marsischky, G.14
Kolodner, R.D.15
Labaer, J.16
Rochet, J.C.17
Bonini, N.M.18
-
25
-
-
0037338634
-
Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria-dependent cell death
-
Darios, F.; Corti, O.; Lucking, C. B.; Hampe, C.; Muriel, M. P.; Abbas, N.; Gu, W. J.; Hirsch, E. C.; Rooney, T.; Ruberg, M.; Brice, A. Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria-dependent cell death. Hum. Mol. Genet. 12(5):517-526; 2003.
-
(2003)
Hum. Mol. Genet
, vol.12
, Issue.5
, pp. 517-526
-
-
Darios, F.1
Corti, O.2
Lucking, C.B.3
Hampe, C.4
Muriel, M.P.5
Abbas, N.6
Gu, W.J.7
Hirsch, E.C.8
Rooney, T.9
Ruberg, M.10
Brice, A.11
-
26
-
-
0242363670
-
Molecular pathways of neurodegeneration in Parkinson's disease
-
Dawson, T. M.; Dawson, V. L. Molecular pathways of neurodegeneration in Parkinson's disease. Science 302(5646):819-822; 2003.
-
(2003)
Science
, vol.302
, Issue.5646
, pp. 819-822
-
-
Dawson, T.M.1
Dawson, V.L.2
-
27
-
-
33745919520
-
Epidemiology of Parkinson's disease
-
de Lau, L. M.; Breteler, M. M. Epidemiology of Parkinson's disease. Lancet Neurol. 5(6):525-535; 2006.
-
(2006)
Lancet Neurol
, vol.5
, Issue.6
, pp. 525-535
-
-
de Lau, L.M.1
Breteler, M.M.2
-
28
-
-
27144469287
-
Small interfering RNA targeting the PINK1 induces apoptosis in dopaminergic cells SH-SY5Y
-
Deng, H.; Jankovic, J.; Guo, Y.; Xie, W.; Le, W. Small interfering RNA targeting the PINK1 induces apoptosis in dopaminergic cells SH-SY5Y. Biochem. Biophys. Res. Commun. 337(4):1133-1138; 2005.
-
(2005)
Biochem. Biophys. Res. Commun
, vol.337
, Issue.4
, pp. 1133-1138
-
-
Deng, H.1
Jankovic, J.2
Guo, Y.3
Xie, W.4
Le, W.5
-
29
-
-
44049099669
-
Mitochondrial import and accumulation of α-synuclein impair complex I in human dopaminergic neuronal cultures and Parkinson disease brain
-
Devi, L.; Raghavendran, V.; Prabhu, B. M.; Avadhani, N. G.; Anandatheerthavarada, H. K. Mitochondrial import and accumulation of α-synuclein impair complex I in human dopaminergic neuronal cultures and Parkinson disease brain. J. Biol. Chem. 283(14):9089-9100; 2008.
-
(2008)
J. Biol. Chem
, vol.283
, Issue.14
, pp. 9089-9100
-
-
Devi, L.1
Raghavendran, V.2
Prabhu, B.M.3
Avadhani, N.G.4
Anandatheerthavarada, H.K.5
-
30
-
-
0029657947
-
Cytoskeletal pathology in non-Alzheimer degenerative dementia: New lesions in diffuse Lewy body disease, Pick's disease, and corticobasal degeneration
-
Dickson, D. W.; Feany, M. B.; Yen, S. H.; Mattiace, L. A.; Davies, P. Cytoskeletal pathology in non-Alzheimer degenerative dementia: New lesions in diffuse Lewy body disease, Pick's disease, and corticobasal degeneration. J. Neural Transm. Suppl 47:31-46; 1996.
-
(1996)
J. Neural Transm. Suppl
, vol.47
, pp. 31-46
-
-
Dickson, D.W.1
Feany, M.B.2
Yen, S.H.3
Mattiace, L.A.4
Davies, P.5
-
31
-
-
34248182509
-
ATP13A2 missense mutations in juvenile parkinsonism and young onset Parkinson disease
-
Di Fonzo, A.; Chien, H. F.; Socal, M.; Giraudo, S.; Tassorelli, C.; Iliceto, G.; Fabbrini, G.; Marconi, R.; Fincati, E.; Abbruzzese, G.; Marini, P.; Squitieri, F.; Horstink, M. W.; Montagna, P.; Libera, A. D.; Stocchi, F.; Goldwurm, S.; Ferreira, J. J.; Meco, G.; Martignoni, E.; Lopiano, L.; Jardim, L. B.; Oostra, B. A.; Barbosa, E. R.; Bonifati, V. ATP13A2 missense mutations in juvenile parkinsonism and young onset Parkinson disease. Neurology 68(19):1557-1562; 2007.
-
(2007)
Neurology
, vol.68
, Issue.19
, pp. 1557-1562
-
-
Di Fonzo, A.1
Chien, H.F.2
Socal, M.3
Giraudo, S.4
Tassorelli, C.5
Iliceto, G.6
Fabbrini, G.7
Marconi, R.8
Fincati, E.9
Abbruzzese, G.10
Marini, P.11
Squitieri, F.12
Horstink, M.W.13
Montagna, P.14
Libera, A.D.15
Stocchi, F.16
Goldwurm, S.17
Ferreira, J.J.18
Meco, G.19
Martignoni, E.20
Lopiano, L.21
Jardim, L.B.22
Oostra, B.A.23
Barbosa, E.R.24
Bonifati, V.25
more..
-
32
-
-
50149098605
-
Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons
-
Dimos, J. T.; Rodolfa, K. T.; Niakan, K. K.; Weisenthal, L. M.; Mitsumoto, H.; Chung, W.; Croft, G. F.; Saphier, G.; Leibel, R.; Goland, R.; Wichterle, H.; Henderson, C. E.; Eggan, K. Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons. Science 321(5893):1218-1221; 2008.
-
(2008)
Science
, vol.321
, Issue.5893
, pp. 1218-1221
-
-
Dimos, J.T.1
Rodolfa, K.T.2
Niakan, K.K.3
Weisenthal, L.M.4
Mitsumoto, H.5
Chung, W.6
Croft, G.F.7
Saphier, G.8
Leibel, R.9
Goland, R.10
Wichterle, H.11
Henderson, C.E.12
Eggan, K.13
-
33
-
-
3142582005
-
A femtomolar acting octapeptide interacts with tubulin and protects astrocytes against zinc intoxication
-
Divinski, I.; Mittelman, L.; Gozes, I. A femtomolar acting octapeptide interacts with tubulin and protects astrocytes against zinc intoxication. J. Biol. Chem. 279(27):28531-28538; 2004.
-
(2004)
J. Biol. Chem
, vol.279
, Issue.27
, pp. 28531-28538
-
-
Divinski, I.1
Mittelman, L.2
Gozes, I.3
-
35
-
-
58249110796
-
Induced pluripotent stem cells from a spinal muscular atrophy patient
-
Ebert, A. D.; Yu, J.; Rose, Jr., F. F.; Mattis, V. B.; Lorson, C. L.; Thomson, J. A.; Svendsen, C. N. Induced pluripotent stem cells from a spinal muscular atrophy patient. Nature 457(7227):277-280; 2009.
-
(2009)
Nature
, vol.457
, Issue.7227
, pp. 277-280
-
-
Ebert, A.D.1
Yu, J.2
Rose, F.F.3
Mattis, V.B.4
Lorson, C.L.5
Thomson, J.A.6
Svendsen, C.N.7
-
36
-
-
0042933863
-
Both apoptosis and necrosis occur early after intracerebral grafting of ventral mesencephalic tissue: A role for protease activation
-
Emgard, M.; Hallin, U.; Karlsson, J.; Bahr, B. A.; Brundin, P.; Blomgren, K. Both apoptosis and necrosis occur early after intracerebral grafting of ventral mesencephalic tissue: A role for protease activation. J. Neurochem. 86(5):1223-1232; 2003.
-
(2003)
J. Neurochem
, vol.86
, Issue.5
, pp. 1223-1232
-
-
Emgard, M.1
Hallin, U.2
Karlsson, J.3
Bahr, B.A.4
Brundin, P.5
Blomgren, K.6
-
37
-
-
0033863483
-
Organization of the human synphilin-1 gene, a candidate for Parkinson's disease
-
Engelender, S.; Wanner, T.; Kleiderlein, J. J.; Wakabayashi, K.; Tsuji, S.; Takahashi, H.; Ashworth, R.; Margolis, R. L.; Ross, C. A. Organization of the human synphilin-1 gene, a candidate for Parkinson's disease. Mamm. Genome 11(9):763-766; 2000.
-
(2000)
Mamm. Genome
, vol.11
, Issue.9
, pp. 763-766
-
-
Engelender, S.1
Wanner, T.2
Kleiderlein, J.J.3
Wakabayashi, K.4
Tsuji, S.5
Takahashi, H.6
Ashworth, R.7
Margolis, R.L.8
Ross, C.A.9
-
38
-
-
0034603178
-
The hsp90-related protein TRAP1 is a mitochondrial protein with distinct functional properties
-
Felts, S. J.; Owen, B. A.; Nguyen, P.; Trepel, J.; Donner, D. B.; Toft, D. O. The hsp90-related protein TRAP1 is a mitochondrial protein with distinct functional properties. J. Biol. Chem. 275(5):3305-3312; 2000.
-
(2000)
J. Biol. Chem
, vol.275
, Issue.5
, pp. 3305-3312
-
-
Felts, S.J.1
Owen, B.A.2
Nguyen, P.3
Trepel, J.4
Donner, D.B.5
Toft, D.O.6
-
39
-
-
2942584868
-
NMR of α-synuclein-polyamine complexes elucidates the mechanism and kinetics of induced aggregation
-
Fernandez, C. O.; Hoyer, W.; Zweckstetter, M.; Jares- Erijman, E. A.; Subramaniam, V.; Griesinger, C.; Jovin, T. M. NMR of α-synuclein-polyamine complexes elucidates the mechanism and kinetics of induced aggregation. EMBO J. 23(10):2039-2046; 2004.
-
(2004)
EMBO J
, vol.23
, Issue.10
, pp. 2039-2046
-
-
Fernandez, C.O.1
Hoyer, W.2
Zweckstetter, M.3
Jares-Erijman, E.A.4
Subramaniam, V.5
Griesinger, C.6
Jovin, T.M.7
-
40
-
-
79951852318
-
A pilot trial of the microtubule- interacting peptide (NAP) in mice overexpressing α-synuclein shows improvement in motor function and reduction of α-synuclein inclusions
-
Fleming, S. M.; Mulligan, C. K.; Richter, F.; Mortazavi, F.; Lemesre, V.; Frias, C.; Zhu, C.; Stewart, A.; Gozes, I.; Morimoto, B.; Chesselet, M. F. A pilot trial of the microtubule- interacting peptide (NAP) in mice overexpressing α-synuclein shows improvement in motor function and reduction of α-synuclein inclusions. Mol. Cell. Neurosci. 46(3):597-606; 2011.
-
(2011)
Mol. Cell. Neurosci
, vol.46
, Issue.3
, pp. 597-606
-
-
Fleming, S.M.1
Mulligan, C.K.2
Richter, F.3
Mortazavi, F.4
Lemesre, V.5
Frias, C.6
Zhu, C.7
Stewart, A.8
Gozes, I.9
Morimoto, B.10
Chesselet, M.F.11
-
41
-
-
0029981526
-
Neuropathology of Parkinson's disease
-
Forno, L. S. Neuropathology of Parkinson's disease. J. Neuropathol. Exp. Neurol. 55(3):259-272; 1996.
-
(1996)
J. Neuropathol. Exp. Neurol
, vol.55
, Issue.3
, pp. 259-272
-
-
Forno, L.S.1
-
42
-
-
34147109175
-
Phenotypic variation in a large Swedish pedigree due to SNCA duplication and triplication
-
Fuchs, J.; Nilsson, C.; Kachergus, J.; Munz, M.; Larsson, E. M.; Schule, B.; Langston, J. W.; Middleton, F. A.; Ross, O. A.; Hulihan, M.; Gasser, T.; Farrer, M. J. Phenotypic variation in a large Swedish pedigree due to SNCA duplication and triplication. Neurology 68(12):916-922; 2007.
-
(2007)
Neurology
, vol.68
, Issue.12
, pp. 916-922
-
-
Fuchs, J.1
Nilsson, C.2
Kachergus, J.3
Munz, M.4
Larsson, E.M.5
Schule, B.6
Langston, J.W.7
Middleton, F.A.8
Ross, O.A.9
Hulihan, M.10
Gasser, T.11
Farrer, M.J.12
-
43
-
-
33645790701
-
LRRK2 expression linked to dopamineinnervated areas
-
Galter, D.; Westerlund, M.; Carmine, A.; Lindqvist, E.; Sydow, O.; Olson, L. LRRK2 expression linked to dopamineinnervated areas. Ann. Neurol. 59(4):714-719; 2006.
-
(2006)
Ann. Neurol
, vol.59
, Issue.4
, pp. 714-719
-
-
Galter, D.1
Westerlund, M.2
Carmine, A.3
Lindqvist, E.4
Sydow, O.5
Olson, L.6
-
44
-
-
0029127954
-
Characterization of a novel protein regulated during the critical period for song learning in the zebra finch
-
George, J. M.; Jin, H.; Woods, W. S.; Clayton, D. F. Characterization of a novel protein regulated during the critical period for song learning in the zebra finch. Neuron 15(2):361-372; 1995.
-
(1995)
Neuron
, vol.15
, Issue.2
, pp. 361-372
-
-
George, J.M.1
Jin, H.2
Woods, W.S.3
Clayton, D.F.4
-
45
-
-
0037148074
-
Neuroprotection in the rat Parkinson model by intrastriatal GDNF gene transfer using a lentiviral vector
-
Georgievska, B.; Kirik, D.; Rosenblad, C.; Lundberg, C.; Bjorklund, A. Neuroprotection in the rat Parkinson model by intrastriatal GDNF gene transfer using a lentiviral vector. Neuroreport 13(1):75-82; 2002.
-
(2002)
Neuroreport
, vol.13
, Issue.1
, pp. 75-82
-
-
Georgievska, B.1
Kirik, D.2
Rosenblad, C.3
Lundberg, C.4
Bjorklund, A.5
-
46
-
-
0026492005
-
Disease-specific patterns of locus coeruleus cell loss
-
German, D. C.; Manaye, K. F.; White, III. C. L.; Woodward, D. J.; McIntire, D. D.; Smith, W. K.; Kalaria, R. N.; Mann, D. M. Disease-specific patterns of locus coeruleus cell loss. Ann. Neurol. 32(5):667-676; 1992.
-
(1992)
Ann. Neurol
, vol.32
, Issue.5
, pp. 667-676
-
-
German, D.C.1
Manaye, K.F.2
White III C., L.3
Woodward, D.J.4
McIntire, D.D.5
Smith, W.K.6
Kalaria, R.N.7
Mann, D.M.8
-
47
-
-
19944432921
-
A common LRRK2 mutation in idiopathic Parkinson's disease
-
Gilks, W. P.; bou-Sleiman, P. M.; Gandhi, S.; Jain, S.; Singleton, A.; Lees, A. J.; Shaw, K.; Bhatia, K. P.; Bonifati, V.; Quinn, N. P.; Lynch, J.; Healy, D. G.; Holton, J. L.; Revesz, T.; Wood, N. W. A common LRRK2 mutation in idiopathic Parkinson's disease. Lancet 365(9457):415-416; 2005.
-
(2005)
Lancet
, vol.365
, Issue.9457
, pp. 415-416
-
-
Gilks, W.P.1
Bou-Sleiman, P.M.2
Gandhi, S.3
Jain, S.4
Singleton, A.5
Lees, A.J.6
Shaw, K.7
Bhatia, K.P.8
Bonifati, V.9
Quinn, N.P.10
Lynch, J.11
Healy, D.G.12
Holton, J.L.13
Revesz, T.14
Wood, N.W.15
-
48
-
-
61349147706
-
α-Synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity
-
Gitler, A. D.; Chesi, A.; Geddie, M. L.; Strathearn, K. E.; Hamamichi, S.; Hill, K. J.; Caldwell, K. A.; Caldwell, G. A.; Cooper, A. A.; Rochet, J. C.; Lindquist, S. α-Synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity. Nat. Genet. 41(3):308-315; 2009.
-
(2009)
Nat. Genet
, vol.41
, Issue.3
, pp. 308-315
-
-
Gitler, A.D.1
Chesi, A.2
Geddie, M.L.3
Strathearn, K.E.4
Hamamichi, S.5
Hill, K.J.6
Caldwell, K.A.7
Caldwell, G.A.8
Cooper, A.A.9
Rochet, J.C.10
Lindquist, S.11
-
49
-
-
13444287985
-
The femtomolar-acting NAP interacts with microtubules: Novel aspects of astrocyte protection
-
Gozes, I.; Divinski, I. The femtomolar-acting NAP interacts with microtubules: Novel aspects of astrocyte protection. J. Alzheimers Dis. 6(6 Suppl):S37-S41; 2004.
-
(2004)
J. Alzheimers Dis
, vol.6
, Issue.6 SUPPL
-
-
Gozes, I.1
Divinski, I.2
-
50
-
-
15544380902
-
Genetic and genomic studies of Drosophila parkin mutants implicate oxidative stress and innate immune responses in pathogenesis
-
Greene, J. C.; Whitworth, A. J.; Andrews, L. A.; Parker, T. J.; Pallanck, L. J. Genetic and genomic studies of Drosophila parkin mutants implicate oxidative stress and innate immune responses in pathogenesis. Hum. Mol. Genet. 14(6):799-811; 2005.
-
(2005)
Hum. Mol. Genet
, vol.14
, Issue.6
, pp. 799-811
-
-
Greene, J.C.1
Whitworth, A.J.2
Andrews, L.A.3
Parker, T.J.4
Pallanck, L.J.5
-
51
-
-
0037386532
-
Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants
-
Greene, J. C.; Whitworth, A. J.; Kuo, I.; Andrews, L. A.; Feany, M. B.; Pallanck, L. J. Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants. Proc. Natl. Acad. Sci. USA 100(7):4078-4083; 2003.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, Issue.7
, pp. 4078-4083
-
-
Greene, J.C.1
Whitworth, A.J.2
Kuo, I.3
Andrews, L.A.4
Feany, M.B.5
Pallanck, L.J.6
-
52
-
-
77953448140
-
Deep brain stimulation in Parkinson's disease
-
Groiss, S. J.; Wojtecki, L.; Sudmeyer, M.; Schnitzler, A. Deep brain stimulation in Parkinson's disease. Ther. Adv. Neurol. Disord. 2(6):20-28; 2009.
-
(2009)
Ther. Adv. Neurol. Disord
, vol.2
, Issue.6
, pp. 20-28
-
-
Groiss, S.J.1
Wojtecki, L.2
Sudmeyer, M.3
Schnitzler, A.4
-
53
-
-
31944450798
-
Increased survival and migration of engrafted mesen-chymal bone marrow stem cells in 6-hydroxydopamine- lesioned rodents
-
Hellmann, M. A.; Panet, H.; Barhum, Y.; Melamed, E.; Offen, D. Increased survival and migration of engrafted mesen-chymal bone marrow stem cells in 6-hydroxydopamine- lesioned rodents. Neurosci. Lett. 395(2):124-128; 2006.
-
(2006)
Neurosci. Lett
, vol.395
, Issue.2
, pp. 124-128
-
-
Hellmann, M.A.1
Panet, H.2
Barhum, Y.3
Melamed, E.4
Offen, D.5
-
54
-
-
0023740954
-
Melanized dopaminergic neurons are differentially susceptible to degeneration in Parkinson's disease
-
Hirsch, E.; Graybiel, A. M.; Agid, Y. A. Melanized dopaminergic neurons are differentially susceptible to degeneration in Parkinson's disease. Nature 334(6180):345-348; 1988.
-
(1988)
Nature
, vol.334
, Issue.6180
, pp. 345-348
-
-
Hirsch, E.1
Graybiel, A.M.2
Agid, Y.A.3
-
55
-
-
0016836934
-
Formation of a functional adrenergic input to intraocular cerebellar grafts: Ingrowth of inhibitory sympathetic fibers
-
Hoffer, B.; Olson, L.; Seiger, A.; Bloom, F. Formation of a functional adrenergic input to intraocular cerebellar grafts: Ingrowth of inhibitory sympathetic fibers. J. Neurobiol. 6(6):565-585; 1975.
-
(1975)
J. Neurobiol
, vol.6
, Issue.6
, pp. 565-585
-
-
Hoffer, B.1
Olson, L.2
Seiger, A.3
Bloom, F.4
-
56
-
-
0033028667
-
No mutation of G209A in the α-synuclein gene in sporadic Parkinson's disease among Taiwan Chinese
-
Hu, C. J.; Sung, S. M.; Liu, H.; Chang, J. G. No mutation of G209A in the α-synuclein gene in sporadic Parkinson's disease among Taiwan Chinese. Eur. Neurol. 41(2):85- 87; 1999.
-
(1999)
Eur. Neurol. 41(2):85-
, pp. 87
-
-
Hu, C.J.1
Sung, S.M.2
Liu, H.3
Chang, J.G.4
-
57
-
-
58449106639
-
α-Synuclein gene rearrangements in dominantly inherited parkinsonism: Frequency, phenotype, and mechanisms
-
Ibáñez, P.; Lesage, S.; Janin, S.; Lohmann, E.; Durif, F.; Destee, A.; Bonnet, A. M.; Brefel-Courbon, C.; Heath, S.; Zelenika, D.; Agid, Y.; Durr, A.; Brice, A. α-Synuclein gene rearrangements in dominantly inherited parkinsonism: Frequency, phenotype, and mechanisms. Arch. Neurol. 66(1):102-108; 2009.
-
(2009)
Arch. Neurol
, vol.66
, Issue.1
, pp. 102-108
-
-
Ibáñez, P.1
Lesage, S.2
Janin, S.3
Lohmann, E.4
Durif, F.5
Destee, A.6
Bonnet, A.M.7
Brefel-Courbon, C.8
Heath, S.9
Zelenika, D.10
Agid, Y.11
Durr, A.12
Brice, A.13
-
58
-
-
33244482539
-
Mutational analysis of the PINK1 gene in early-onset parkinsonism in Europe and North Africa
-
Ibáñez, P.; Lesage, S.; Lohmann, E.; Thobois, S.; De Michele, G.; Borg, M.; Agid, Y.; Durr, A.; Brice, A. Mutational analysis of the PINK1 gene in early-onset parkinsonism in Europe and North Africa. Brain 129(Pt 3): 686-694; 2006.
-
(2006)
Brain
, vol.129
, Issue.PART 3
, pp. 686-694
-
-
Ibáñez, P.1
Lesage, S.2
Lohmann, E.3
Thobois, S.4
de Michele, G.5
Borg, M.6
Agid, Y.7
Durr, A.8
Brice, A.9
-
59
-
-
51949090816
-
Phosphorylation of 4E-BP by LRRK2 affects the maintenance of dopaminergic neurons in Drosophila
-
Imai, Y.; Gehrke, S.; Wang, H. Q.; Takahashi, R.; Hasegawa, K.; Oota, E.; Lu, B. Phosphorylation of 4E-BP by LRRK2 affects the maintenance of dopaminergic neurons in Drosophila. EMBO J. 27(18):2432-2443; 2008.
-
(2008)
EMBO J
, vol.27
, Issue.18
, pp. 2432-2443
-
-
Imai, Y.1
Gehrke, S.2
Wang, H.Q.3
Takahashi, R.4
Hasegawa, K.5
Oota, E.6
Lu, B.7
-
60
-
-
59149090357
-
Polo-like kinase 2 (PLK2) phosphorylates α-synuclein at serine 129 in central nervous system
-
Inglis, K. J.; Chereau, D.; Brigham, E. F.; Chiou, S. S.; Schobel, S.; Frigon, N. L.; Yu, M.; Caccavello, R. J.; Nelson, S.; Motter, R.; Wright, S.; Chian, D.; Santiago, P.; Soriano, F.; Ramos, C.; Powell, K.; Goldstein, J. M.; Babcock, M.; Yednock, T.; Bard, F.; Basi, G. S.; Sham, H.; Chilcote, T. J.; McConlogue, L.; Griswold-Prenner, I.; Anderson, J. P. Polo-like kinase 2 (PLK2) phosphorylates α-synuclein at serine 129 in central nervous system. J. Biol. Chem. 284(5):2598-2602; 2009.
-
(2009)
J. Biol. Chem
, vol.284
, Issue.5
, pp. 2598-2602
-
-
Inglis, K.J.1
Chereau, D.2
Brigham, E.F.3
Chiou, S.S.4
Schobel, S.5
Frigon, N.L.6
Yu, M.7
Caccavello, R.J.8
Nelson, S.9
Motter, R.10
Wright, S.11
Chian, D.12
Santiago, P.13
Soriano, F.14
Ramos, C.15
Powell, K.16
Goldstein, J.M.17
Babcock, M.18
Yednock, T.19
Bard, F.20
Basi, G.S.21
Sham, H.22
Chilcote, T.J.23
McConlogue, L.24
Griswold-Prenner, I.25
Anderson, J.P.26
more..
-
61
-
-
34547762298
-
More frequent Lewy bodies but less frequent Alzheimer-type lesions in multiple system atrophy as compared to age-matched control brains
-
Jellinger, K. A. More frequent Lewy bodies but less frequent Alzheimer-type lesions in multiple system atrophy as compared to age-matched control brains. Acta Neuropathol. 114(3):299-303; 2007.
-
(2007)
Acta Neuropathol
, vol.114
, Issue.3
, pp. 299-303
-
-
Jellinger, K.A.1
-
62
-
-
0026348872
-
Pathology of Parkinson's disease. Changes other than the nigrostriatal pathway
-
Jellinger, K. A. Pathology of Parkinson's disease. Changes other than the nigrostriatal pathway. Mol. Chem. Neuropathol. 14(3):153-197; 1991.
-
(1991)
Mol. Chem. Neuropathol
, vol.14
, Issue.3
, pp. 153-197
-
-
Jellinger, K.A.1
-
63
-
-
0033520474
-
α-Synuclein binds to Tau and stimulates the protein kinase α-catalyzed tau phosphorylation of serine residues 262 and 356
-
Jensen, P. H.; Hager, H.; Nielsen, M. S.; Hojrup, P.; Gliemann, J.; Jakes, R. α-Synuclein binds to Tau and stimulates the protein kinase α-catalyzed tau phosphorylation of serine residues 262 and 356. J. Biol. Chem. 274(36):25481-25489; 1999.
-
(1999)
J. Biol. Chem
, vol.274
, Issue.36
, pp. 25481-25489
-
-
Jensen, P.H.1
Hager, H.2
Nielsen, M.S.3
Hojrup, P.4
Gliemann, J.5
Jakes, R.6
-
64
-
-
77958450202
-
Inhibition of mitochondrial fusion by α-synuclein is rescued by PINK1, Parkin and DJ-1
-
Kamp, F.; Exner, N.; Lutz, A. K.; Wender, N.; Hegermann, J.; Brunner, B.; Nuscher, B.; Bartels, T.; Giese, A.; Beyer, K.; Eimer, S.; Winklhofer, K. F.; Haass, C. Inhibition of mitochondrial fusion by α-synuclein is rescued by PINK1, Parkin and DJ-1. EMBO J. 29(20):3571-3589; 2010.
-
(2010)
EMBO J
, vol.29
, Issue.20
, pp. 3571-3589
-
-
Kamp, F.1
Exner, N.2
Lutz, A.K.3
Wender, N.4
Hegermann, J.5
Brunner, B.6
Nuscher, B.7
Bartels, T.8
Giese, A.9
Beyer, K.10
Eimer, S.11
Winklhofer, K.F.12
Haass, C.13
-
65
-
-
3543023308
-
Efficient induction of dopaminergic neurons from embryonic stem cells for application to Parkinson's disease
-
Kim, D. W. Efficient induction of dopaminergic neurons from embryonic stem cells for application to Parkinson's disease. Yonsei Med. J. 45 Suppl:23-27; 2004.
-
(2004)
Yonsei Med. J
, vol.45
, Issue.SUPPL
, pp. 23-27
-
-
Kim, D.W.1
-
66
-
-
36849008768
-
Impairment of microtubule system increases asynuclein aggregation and toxicity
-
Kim, M.; Jung, W.; Lee, I. H.; Bhak, G.; Paik, S. R.; Hahn, J. S. Impairment of microtubule system increases asynuclein aggregation and toxicity. Biochem. Biophys. Res. Commun. 365(4):628-635; 2008.
-
(2008)
Biochem. Biophys. Res. Commun
, vol.365
, Issue.4
, pp. 628-635
-
-
Kim, M.1
Jung, W.2
Lee, I.H.3
Bhak, G.4
Paik, S.R.5
Hahn, J.S.6
-
67
-
-
1842740232
-
Cysteine-106 of DJ-1 is the most sensitive cysteine residue to hydrogen peroxide-mediated oxidation in vivo in human umbilical vein endothelial cells
-
Kinumi, T.; Kimata, J.; Taira, T.; Ariga, H.; Niki, E. Cysteine-106 of DJ-1 is the most sensitive cysteine residue to hydrogen peroxide-mediated oxidation in vivo in human umbilical vein endothelial cells. Biochem. Biophys. Res. Commun. 317(3):722-728; 2004.
-
(2004)
Biochem. Biophys. Res. Commun
, vol.317
, Issue.3
, pp. 722-728
-
-
Kinumi, T.1
Kimata, J.2
Taira, T.3
Ariga, H.4
Niki, E.5
-
68
-
-
0036550101
-
Parkinson-like neurodegeneration induced by targeted overexpression of α-synuclein in the nigrostriatal system
-
Kirik, D.; Rosenblad, C.; Burger, C.; Lundberg, C.; Johansen, T. E.; Muzyczka, N.; Mandel, R. J.; Bjorklund, A. Parkinson-like neurodegeneration induced by targeted overexpression of α-synuclein in the nigrostriatal system. J. Neurosci. 22(7):2780-2791; 2002.
-
(2002)
J. Neurosci
, vol.22
, Issue.7
, pp. 2780-2791
-
-
Kirik, D.1
Rosenblad, C.2
Burger, C.3
Lundberg, C.4
Johansen, T.E.5
Muzyczka, N.6
Mandel, R.J.7
Bjorklund, A.8
-
69
-
-
34250372427
-
Deciphering the role of heterozygous mutations in genes associated with parkinsonism
-
Klein, C.; Lohmann-Hedrich, K.; Rogaeva, E.; Schlossmacher, M. G.; Lang, A. E. Deciphering the role of heterozygous mutations in genes associated with parkinsonism. Lancet Neurol. 6(7):652-662; 2007.
-
(2007)
Lancet Neurol
, vol.6
, Issue.7
, pp. 652-662
-
-
Klein, C.1
Lohmann-Hedrich, K.2
Rogaeva, E.3
Schlossmacher, M.G.4
Lang, A.E.5
-
71
-
-
33749583553
-
α-Synuclein acts in the nucleus to inhibit histone acetylation and promote neurotoxicity
-
Kontopoulos, E.; Parvin, J. D.; Feany, M. B. α-Synuclein acts in the nucleus to inhibit histone acetylation and promote neurotoxicity. Hum. Mol. Genet. 15(20):3012-3023; 2006.
-
(2006)
Hum. Mol. Genet
, vol.15
, Issue.20
, pp. 3012-3023
-
-
Kontopoulos, E.1
Parvin, J.D.2
Feany, M.B.3
-
72
-
-
43249114934
-
Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease
-
Kordower, J. H.; Chu, Y.; Hauser, R. A.; Freeman, T. B.; Olanow, C. W. Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease. Nat. Med. 14(5):504-506; 2008.
-
(2008)
Nat. Med
, vol.14
, Issue.5
, pp. 504-506
-
-
Kordower, J.H.1
Chu, Y.2
Hauser, R.A.3
Freeman, T.B.4
Olanow, C.W.5
-
73
-
-
0035723905
-
Review of the functional surgical treatment of dystonia
-
Krack, P.; Vercueil, L. Review of the functional surgical treatment of dystonia. Eur. J. Neurol. 8(5):389-399; 2001.
-
(2001)
Eur. J. Neurol
, vol.8
, Issue.5
, pp. 389-399
-
-
Krack, P.1
Vercueil, L.2
-
74
-
-
33646351299
-
Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons
-
Kraytsberg, Y.; Kudryavtseva, E.; McKee, A. C.; Geula, C.; Kowall, N. W.; Khrapko, K. Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons. Nat. Genet. 38(5): 518-520; 2006.
-
(2006)
Nat. Genet
, vol.38
, Issue.5
, pp. 518-520
-
-
Kraytsberg, Y.1
Kudryavtseva, E.2
McKee, A.C.3
Geula, C.4
Kowall, N.W.5
Khrapko, K.6
-
75
-
-
0031990490
-
Ala30Pro mutation in the gene encoding α-synuclein in Parkinson's disease
-
Kruger, R.; Kuhn, W.; Muller, T.; Woitalla, D.; Graeber, M.; Kosel, S.; Przuntek, H.; Epplen, J. T.; Schols, L.; Riess, O. Ala30Pro mutation in the gene encoding α-synuclein in Parkinson's disease. Nat. Genet. 18(2):106-108; 1998.
-
(1998)
Nat. Genet
, vol.18
, Issue.2
, pp. 106-108
-
-
Kruger, R.1
Kuhn, W.2
Muller, T.3
Woitalla, D.4
Graeber, M.5
Kosel, S.6
Przuntek, H.7
Epplen, J.T.8
Schols, L.9
Riess, O.10
-
76
-
-
41649096247
-
Mutations in the GIGYF2 (TNRC15) gene at the PARK11 locus in familial Parkinson disease
-
Lautier, C.; Goldwurm, S.; Durr, A.; Giovannone, B.; Tsiaras, W. G.; Pezzoli, G.; Brice, A.; Smith, R. J. Mutations in the GIGYF2 (TNRC15) gene at the PARK11 locus in familial Parkinson disease. Am. J. Hum. Genet. 82(4): 822-833; 2008.
-
(2008)
Am. J. Hum. Genet
, vol.82
, Issue.4
, pp. 822-833
-
-
Lautier, C.1
Goldwurm, S.2
Durr, A.3
Giovannone, B.4
Tsiaras, W.G.5
Pezzoli, G.6
Brice, A.7
Smith, R.J.8
-
77
-
-
0032692692
-
Reduced Nurr1 expression increases the vulnerability of mesencephalic dopamine neurons to MPTP-induced injury
-
Le, W.; Conneely, O. M.; He, Y.; Jankovic, J.; Appel, S. H. Reduced Nurr1 expression increases the vulnerability of mesencephalic dopamine neurons to MPTP-induced injury. J. Neurochem. 73(5):2218-2221; 1999.
-
(1999)
J. Neurochem
, vol.73
, Issue.5
, pp. 2218-2221
-
-
Le, W.1
Conneely, O.M.2
He, Y.3
Jankovic, J.4
Appel, S.H.5
-
78
-
-
0037226797
-
Mutations in NR4A2 associated with familial Parkinson disease. Nat
-
Le, W. D.; Xu, P.; Jankovic, J.; Jiang, H.; Appel, S. H.; Smith, R. G.; Vassilatis, D. K. Mutations in NR4A2 associated with familial Parkinson disease. Nat. Genet. 33(1):85-89; 2003.
-
(2003)
Genet
, vol.33
, Issue.1
, pp. 85-89
-
-
Le, W.D.1
Xu, P.2
Jankovic, J.3
Jiang, H.4
Appel, S.H.5
Smith, R.G.6
Vassilatis, D.K.7
-
79
-
-
33845656077
-
Impairment of microtubule-dependent trafficking by overexpression of α-synuclein
-
Lee, H. J.; Khoshaghideh, F.; Lee, S.; Lee, S. J. Impairment of microtubule-dependent trafficking by overexpression of α-synuclein. Eur. J. Neurosci. 24(11):3153-3162; 2006.
-
(2006)
Eur. J. Neurosci
, vol.24
, Issue.11
, pp. 3153-3162
-
-
Lee, H.J.1
Khoshaghideh, F.2
Lee, S.3
Lee, S.J.4
-
80
-
-
0032190090
-
The ubiquitin pathway in Parkinson's disease
-
Leroy, E.; Boyer, R.; Auburger, G.; Leube, B.; Ulm, G.; Mezey, E.; Harta, G.; Brownstein, M. J.; Jonnalagada, S.; Chernova, T.; Dehejia, A.; Lavedan, C.; Gasser, T.; Steinbach, P. J.; Wilkinson, K. D.; Polymeropoulos, M. H. The ubiquitin pathway in Parkinson's disease. Nature 395 (6701):451-452; 1998.
-
(1998)
Nature
, vol.395
, Issue.6701
, pp. 451-452
-
-
Leroy, E.1
Boyer, R.2
Auburger, G.3
Leube, B.4
Ulm, G.5
Mezey, E.6
Harta, G.7
Brownstein, M.J.8
Jonnalagada, S.9
Chernova, T.10
Dehejia, A.11
Lavedan, C.12
Gasser, T.13
Steinbach, P.J.14
Wilkinson, K.D.15
Polymeropoulos, M.H.16
-
81
-
-
31344432937
-
LRRK2 G2019S as a cause of Parkinson's disease in North African Arabs
-
Lesage, S.; Durr, A.; Tazir, M.; Lohmann, E.; Leutenegger, A. L.; Janin, S.; Pollak, P.; Brice, A. LRRK2 G2019S as a cause of Parkinson's disease in North African Arabs. N. Engl. J. Med. 354(4):422-423; 2006.
-
(2006)
N. Engl. J. Med
, vol.354
, Issue.4
, pp. 422-423
-
-
Lesage, S.1
Durr, A.2
Tazir, M.3
Lohmann, E.4
Leutenegger, A.L.5
Janin, S.6
Pollak, P.7
Brice, A.8
-
82
-
-
77952476225
-
Parkinson's disease-related LRRK2 G2019S mutation results from independent mutational events in humans
-
Lesage, S.; Patin, E.; Condroyer, C.; Leutenegger, A. L.; Lohmann, E.; Giladi, N.; Bar-Shira, A.; Belarbi, S.; Hecham, N.; Pollak, P.; Ouvrard-Hernandez, A. M.; Bardien, S.; Carr, J.; Benhassine, T.; Tomiyama, H.; Pirkevi, C.; Hamadouche, T.; Cazeneuve, C.; Basak, A. N.; Hattori, N.; Durr, A.; Tazir, M.; Orr-Urtreger, A.; Quintana-Murci, L.; Brice, A. Parkinson's disease-related LRRK2 G2019S mutation results from independent mutational events in humans. Hum. Mol. Genet. 19(10):1998-2004; 2010.
-
(2010)
Hum. Mol. Genet
, vol.19
, Issue.10
, pp. 1998-2004
-
-
Lesage, S.1
Patin, E.2
Condroyer, C.3
Leutenegger, A.L.4
Lohmann, E.5
Giladi, N.6
Bar-Shira, A.7
Belarbi, S.8
Hecham, N.9
Pollak, P.10
Ouvrard-Hernandez, A.M.11
Bardien, S.12
Carr, J.13
Benhassine, T.14
Tomiyama, H.15
Pirkevi, C.16
Hamadouche, T.17
Cazeneuve, C.18
Basak, A.N.19
Hattori, N.20
Durr, A.21
Tazir, M.22
Orr-Urtreger, A.23
Quintana-Murci, L.24
Brice, A.25
more..
-
83
-
-
57449109485
-
Increased asynuclein aggregation following limited cleavage by certain matrix metalloproteinases
-
Levin, J.; Giese, A.; Boetzel, K.; Israel, L.; Hogen, T.; Nubling, G.; Kretzschmar, H.; Lorenzl, S. Increased asynuclein aggregation following limited cleavage by certain matrix metalloproteinases. Exp. Neurol. 215(1):201-208; 2009.
-
(2009)
Exp. Neurol
, vol.215
, Issue.1
, pp. 201-208
-
-
Levin, J.1
Giese, A.2
Boetzel, K.3
Israel, L.4
Hogen, T.5
Nubling, G.6
Kretzschmar, H.7
Lorenzl, S.8
-
84
-
-
0035909960
-
Intracerebral transplantation of bone marrow stromal cells in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease
-
Li, Y.; Chen, J.; Wang, L.; Zhang, L.; Lu, M.; Chopp, M. Intracerebral transplantation of bone marrow stromal cells in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease. Neurosci. Lett. 316(2): 67-70; 2001.
-
(2001)
Neurosci. Lett
, vol.316
, Issue.2
, pp. 67-70
-
-
Li, Y.1
Chen, J.2
Wang, L.3
Zhang, L.4
Lu, M.5
Chopp, M.6
-
85
-
-
77955300299
-
Human umbilical cord blood mononuclear cell transplantation in rats with intrinsic sphincter deficiency
-
Lim, J. J.; Jang, J. B.; Kim, J. Y.; Moon, S. H.; Lee, C. N.; Lee, K. J. Human umbilical cord blood mononuclear cell transplantation in rats with intrinsic sphincter deficiency. J. Korean Med Sci. 25(5):663-670; 2010.
-
(2010)
J. Korean Med Sci
, vol.25
, Issue.5
, pp. 663-670
-
-
Lim, J.J.1
Jang, J.B.2
Kim, J.Y.3
Moon, S.H.4
Lee, C.N.5
Lee, K.J.6
-
86
-
-
0032697860
-
Absence of G209A and G88C mutations in the α-synuclein gene of Parkinson's disease in a Chinese population
-
Lin, J. J.; Yueh, K. C.; Chang, D. C.; Lin, S. Z. Absence of G209A and G88C mutations in the α-synuclein gene of Parkinson's disease in a Chinese population. Eur. Neurol. 42(4):217-220; 1999.
-
(1999)
Eur. Neurol
, vol.42
, Issue.4
, pp. 217-220
-
-
Lin, J.J.1
Yueh, K.C.2
Chang, D.C.3
Lin, S.Z.4
-
87
-
-
0034589755
-
Clinical observations after neural transplantation in Parkinson's disease
-
Lindvall, O.; Hagell, P. Clinical observations after neural transplantation in Parkinson's disease. Prog. Brain Res. 127:299-320; 2000.
-
(2000)
Prog. Brain Res
, vol.127
, pp. 299-320
-
-
Lindvall, O.1
Hagell, P.2
-
88
-
-
16644379457
-
Generation and differentiation of neurospheres from murine embryonic day 14 central nervous system tissue
-
Louis, S. A.; Reynolds, B. A. Generation and differentiation of neurospheres from murine embryonic day 14 central nervous system tissue. Methods Mol. Biol. 290:265-280; 2005.
-
(2005)
Methods Mol. Biol
, vol.290
, pp. 265-280
-
-
Louis, S.A.1
Reynolds, B.A.2
-
89
-
-
18144393448
-
Therapeutic benefit of TH-engineered mesenchymal stem cells for Parkinson's disease
-
Lu, L.; Zhao, C.; Liu, Y.; Sun, X.; Duan, C.; Ji, M.; Zhao, H.; Xu, Q.; Yang, H. Therapeutic benefit of TH-engineered mesenchymal stem cells for Parkinson's disease. Brain Res. Brain Res. Protoc. 15(1):46-51; 2005.
-
(2005)
Brain Res. Brain Res. Protoc
, vol.15
, Issue.1
, pp. 46-51
-
-
Lu, L.1
Zhao, C.2
Liu, Y.3
Sun, X.4
Duan, C.5
Ji, M.6
Zhao, H.7
Xu, Q.8
Yang, H.9
-
90
-
-
0342368772
-
Association between early-onset Parkinson's disease and mutations in the parkin gene
-
Lucking, C. B.; Durr, A.; Bonifati, V.; Vaughan, J.; De Michele, G.; Gasser, T.; Harhangi, B. S.; Meco, G.; Denefle, P.; Wood, N. W.; Agid, Y.; Brice, A. Association between early-onset Parkinson's disease and mutations in the parkin gene. N. Engl. J. Med. 342(21):1560-1567; 2000.
-
(2000)
N. Engl. J. Med
, vol.342
, Issue.21
, pp. 1560-1567
-
-
Lucking, C.B.1
Durr, A.2
Bonifati, V.3
Vaughan, J.4
de Michele, G.5
Gasser, T.6
Harhangi, B.S.7
Meco, G.8
Denefle, P.9
Wood, N.W.10
Agid, Y.11
Brice, A.12
-
91
-
-
78650356896
-
Phosphorylated α-synuclein at Ser-129 is targeted to the proteasome pathway in a ubiquitin-independent manner
-
Machiya, Y.; Hara, S.; Arawaka, S.; Fukushima, S.; Sato, H.; Sakamoto, M.; Koyama, S.; Kato, T. Phosphorylated α-synuclein at Ser-129 is targeted to the proteasome pathway in a ubiquitin-independent manner. J. Biol. Chem. 285(52):40732-40744; 2010.
-
(2010)
J. Biol. Chem
, vol.285
, Issue.52
, pp. 40732-40744
-
-
Machiya, Y.1
Hara, S.2
Arawaka, S.3
Fukushima, S.4
Sato, H.5
Sakamoto, M.6
Koyama, S.7
Kato, T.8
-
92
-
-
33749985102
-
Neural differentiation of human mesenchymal stem cells: Evidence for expression of neural markers and eag K+ channel types
-
Mareschi, K.; Novara, M.; Rustichelli, D.; Ferrero, I.; Guido, D.; Carbone, E.; Medico, E.; Madon, E.; Vercelli, A.; Fagioli, F. Neural differentiation of human mesenchymal stem cells: Evidence for expression of neural markers and eag K+ channel types. Exp. Hematol. 34(11):1563-1572; 2006.
-
(2006)
Exp. Hematol
, vol.34
, Issue.11
, pp. 1563-1572
-
-
Mareschi, K.1
Novara, M.2
Rustichelli, D.3
Ferrero, I.4
Guido, D.5
Carbone, E.6
Medico, E.7
Madon, E.8
Vercelli, A.9
Fagioli, F.10
-
93
-
-
33644531535
-
Cooperative transcription activation by Nurr1 and Pitx3 induces embryonic stem cell maturation to the midbrain dopamine neuron phenotype
-
Martinat, C.; Bacci, J. J.; Leete, T.; Kim, J.; Vanti, W. B.; Newman, A. H.; Cha, J. H.; Gether, U.; Wang, H.; Abeliovich, A. Cooperative transcription activation by Nurr1 and Pitx3 induces embryonic stem cell maturation to the midbrain dopamine neuron phenotype. Proc. Natl. Acad. Sci. USA 103(8):2874-2879; 2006.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, Issue.8
, pp. 2874-2879
-
-
Martinat, C.1
Bacci, J.J.2
Leete, T.3
Kim, J.4
Vanti, W.B.5
Newman, A.H.6
Cha, J.H.7
Gether, U.8
Wang, H.9
Abeliovich, A.10
-
94
-
-
12444281013
-
Identification and functional characterization of a novel R621C mutation in the synphilin-1 gene in Parkinson's disease
-
Marx, F. P.; Holzmann, C.; Strauss, K. M.; Li, L.; Eberhardt, O.; Gerhardt, E.; Cookson, M. R.; Hernandez, D.; Farrer, M. J.; Kachergus, J.; Engelender, S.; Ross, C. A.; Berger, K.; Schols, L.; Schulz, J. B.; Riess, O.; Kruger, R. Identification and functional characterization of a novel R621C mutation in the synphilin-1 gene in Parkinson's disease. Hum. Mol. Genet. 12(11):1223-1231; 2003.
-
(2003)
Hum. Mol. Genet
, vol.12
, Issue.11
, pp. 1223-1231
-
-
Marx, F.P.1
Holzmann, C.2
Strauss, K.M.3
Li, L.4
Eberhardt, O.5
Gerhardt, E.6
Cookson, M.R.7
Hernandez, D.8
Farrer, M.J.9
Kachergus, J.10
Engelender, S.11
Ross, C.A.12
Berger, K.13
Schols, L.14
Schulz, J.B.15
Riess, O.16
Kruger, R.17
-
95
-
-
0034681471
-
Dopaminergic loss and inclusion body formation in α-synuclein mice: Implications for neurodegenerative disorders
-
Masliah, E.; Rockenstein, E.; Veinbergs, I.; Mallory, M.; Hashimoto, M.; Takeda, A.; Sagara, Y.; Sisk, A.; Mucke, L. Dopaminergic loss and inclusion body formation in α-synuclein mice: Implications for neurodegenerative disorders. Science 287(5456):1265-1269; 2000.
-
(2000)
Science
, vol.287
, Issue.5456
, pp. 1265-1269
-
-
Masliah, E.1
Rockenstein, E.2
Veinbergs, I.3
Mallory, M.4
Hashimoto, M.5
Takeda, A.6
Sagara, Y.7
Sisk, A.8
Mucke, L.9
-
96
-
-
77449113371
-
Phosphorylation of synucleins by members of the Polo-like kinase family
-
Mbefo, M. K.; Paleologou, K. E.; Boucharaba, A.; Oueslati, A.; Schell, H.; Fournier, M.; Olschewski, D.; Yin, G.; Zweckstetter, M.; Masliah, E.; Kahle, P. J.; Hirling, H.; Lashuel, H. A. Phosphorylation of synucleins by members of the Polo-like kinase family. J. Biol. Chem. 285(4):2807-2822; 2010.
-
(2010)
J. Biol. Chem
, vol.285
, Issue.4
, pp. 2807-2822
-
-
Mbefo, M.K.1
Paleologou, K.E.2
Boucharaba, A.3
Oueslati, A.4
Schell, H.5
Fournier, M.6
Olschewski, D.7
Yin, G.8
Zweckstetter, M.9
Masliah, E.10
Kahle, P.J.11
Hirling, H.12
Lashuel, H.A.13
-
97
-
-
33646356230
-
Stable expression of a neuronal dopaminergic progenitor phenotype in cell lines derived from human amniotic fluid cells
-
McLaughlin, D.; Tsirimonaki, E.; Vallianatos, G.; Sakellaridis, N.; Chatzistamatiou, T.; Stavropoulos-Gioka, C.; Tsezou, A.; Messinis, I.; Mangoura, D. Stable expression of a neuronal dopaminergic progenitor phenotype in cell lines derived from human amniotic fluid cells. J. Neurosci. Res. 83(7):1190-1200; 2006.
-
(2006)
J. Neurosci. Res
, vol.83
, Issue.7
, pp. 1190-1200
-
-
McLaughlin, D.1
Tsirimonaki, E.2
Vallianatos, G.3
Sakellaridis, N.4
Chatzistamatiou, T.5
Stavropoulos-Gioka, C.6
Tsezou, A.7
Messinis, I.8
Mangoura, D.9
-
98
-
-
41149114560
-
Biochemical aspects of the neuroprotective mechanism of PTEN-induced kinase-1 (PINK1)
-
Mills, R. D.; Sim, C. H.; Mok, S. S.; Mulhern, T. D.; Culvenor, J. G.; Cheng, H. C. Biochemical aspects of the neuroprotective mechanism of PTEN-induced kinase-1 (PINK1). J. Neurochem. 105(1):18-33; 2008.
-
(2008)
J. Neurochem
, vol.105
, Issue.1
, pp. 18-33
-
-
Mills, R.D.1
Sim, C.H.2
Mok, S.S.3
Mulhern, T.D.4
Culvenor, J.G.5
Cheng, H.C.6
-
99
-
-
0035692636
-
DJ-1 is an indicator for endogenous reactive oxygen species elicited by endotoxin
-
Mitsumoto, A.; Nakagawa, Y. DJ-1 is an indicator for endogenous reactive oxygen species elicited by endotoxin. Free Radic. Res. 35(6):885-893; 2001.
-
(2001)
Free Radic. Res
, vol.35
, Issue.6
, pp. 885-893
-
-
Mitsumoto, A.1
Nakagawa, Y.2
-
100
-
-
17044447638
-
Familial Parkinson's disease. α-Synuclein and parkin
-
Mizuno, Y.; Hattori, N.; Kitada, T.; Matsumine, H.; Mori, H.; Shimura, H.; Kubo, S.; Kobayashi, H.; Asakawa, S.; Minoshima, S.; Shimizu, N. Familial Parkinson's disease. α-Synuclein and parkin. Adv. Neurol. 86:13-21; 2001.
-
(2001)
Adv. Neurol
, vol.86
, pp. 13-21
-
-
Mizuno, Y.1
Hattori, N.2
Kitada, T.3
Matsumine, H.4
Mori, H.5
Shimura, H.6
Kubo, S.7
Kobayashi, H.8
Asakawa, S.9
Minoshima, S.10
Shimizu, N.11
-
101
-
-
33745553895
-
PLA2G6, encoding a phospholipase A2, is mutated in neurodegenerative disorders with high brain iron
-
Morgan, N. V.; Westaway, S. K.; Morton, J. E.; Gregory, A.; Gissen, P.; Sonek, S.; Cangul, H.; Coryell, J.; Canham, N.; Nardocci, N.; Zorzi, G.; Pasha, S.; Rodriguez, D.; Desguerre, I.; Mubaidin, A.; Bertini, E.; Trembath, R. C.; Simonati, A.; Schanen, C.; Johnson, C. A.; Levinson, B.; Woods, C. G.; Wilmot, B.; Kramer, P.; Gitschier, J.; Maher, E. R.; Hayflick, S. J. PLA2G6, encoding a phospholipase A2, is mutated in neurodegenerative disorders with high brain iron. Nat. Genet. 38(7):752-754; 2006.
-
(2006)
Nat. Genet
, vol.38
, Issue.7
, pp. 752-754
-
-
Morgan, N.V.1
Westaway, S.K.2
Morton, J.E.3
Gregory, A.4
Gissen, P.5
Sonek, S.6
Cangul, H.7
Coryell, J.8
Canham, N.9
Nardocci, N.10
Zorzi, G.11
Pasha, S.12
Rodriguez, D.13
Desguerre, I.14
Mubaidin, A.15
Bertini, E.16
Trembath, R.C.17
Simonati, A.18
Schanen, C.19
Johnson, C.A.20
Levinson, B.21
Woods, C.G.22
Wilmot, B.23
Kramer, P.24
Gitschier, J.25
Maher, E.R.26
Hayflick, S.J.27
more..
-
102
-
-
28444472442
-
Transplanted human embryonic germ cell-derived neural stem cells replace neurons and oligodendrocytes in the forebrain of neonatal mice with excitotoxic brain damage
-
Mueller, D.; Shamblott, M. J.; Fox, H. E.; Gearhart, J. D.; Martin, L. J. Transplanted human embryonic germ cell-derived neural stem cells replace neurons and oligodendrocytes in the forebrain of neonatal mice with excitotoxic brain damage. J. Neurosci. Res. 82(5):592-608; 2005.
-
(2005)
J. Neurosci. Res
, vol.82
, Issue.5
, pp. 592-608
-
-
Mueller, D.1
Shamblott, M.J.2
Fox, H.E.3
Gearhart, J.D.4
Martin, L.J.5
-
103
-
-
0028298816
-
Pallido-pyramidal degeneration, supranuclear upgaze paresis and dementia: Kufor-Rakeb syndrome
-
Najim al-Din, A. S.; Wriekat, A.; Mubaidin, A.; Dasouki, M.; Hiari, M. Pallido-pyramidal degeneration, supranuclear upgaze paresis and dementia: Kufor-Rakeb syndrome. Acta Neurol. Scand. 89(5):347-352; 1994.
-
(1994)
Acta Neurol. Scand
, vol.89
, Issue.5
, pp. 347-352
-
-
al-Din, A.S.N.1
Wriekat, A.2
Mubaidin, A.3
Dasouki, M.4
Hiari, M.5
-
104
-
-
73549085595
-
Increased expression of α-synuclein reduces neurotransmitter release by inhibiting synaptic vesicle reclustering after endocytosis
-
Nemani, V. M.; Lu, W.; Berge, V.; Nakamura, K.; Onoa, B.; Lee, M. K.; Chaudhry, F. A.; Nicoll, R. A.; Edwards, R. H. Increased expression of α-synuclein reduces neurotransmitter release by inhibiting synaptic vesicle reclustering after endocytosis. Neuron 65(1):66-79; 2010.
-
(2010)
Neuron
, vol.65
, Issue.1
, pp. 66-79
-
-
Nemani, V.M.1
Lu, W.2
Berge, V.3
Nakamura, K.4
Onoa, B.5
Lee, M.K.6
Chaudhry, F.A.7
Nicoll, R.A.8
Edwards, R.H.9
-
105
-
-
78651099224
-
Glucocerebrosidase mutations in diffuse Lewy body disease. Parkinsonism
-
Nishioka, K.; Ross, O. A.; Vilarino-Guell, C.; Cobb, S. A.; Kachergus, J. M.; Mann, D. M.; Snowden, J.; Richardson, A. M.; Neary, D.; Robinson, C. A.; Rajput, A.; Papapetropoulos, S.; Mash, D. C.; Pahwa, R.; Lyons, K. E.; Wszolek, Z. K.; Dickson, D. W.; Farrer, M. J. Glucocerebrosidase mutations in diffuse Lewy body disease. Parkinsonism. Relat. Disord. 17(1):55-57; 2011.
-
(2011)
Relat. Disord
, vol.17
, Issue.1
, pp. 55-57
-
-
Nishioka, K.1
Ross, O.A.2
Vilarino-Guell, C.3
Cobb, S.A.4
Kachergus, J.M.5
Mann, D.M.6
Snowden, J.7
Richardson, A.M.8
Neary, D.9
Robinson, C.A.10
Rajput, A.11
Papapetropoulos, S.12
Mash, D.C.13
Pahwa, R.14
Lyons, K.E.15
Wszolek, Z.K.16
Dickson, D.W.17
Farrer, M.J.18
-
106
-
-
0033964778
-
Vasoactive intestinal peptide (VIP) prevents neurotoxicity in neuronal cultures
-
Offen, D.; Sherki, Y.; Melamed, E.; Fridkin, M.; Brenneman, D. E.; Gozes, I. Vasoactive intestinal peptide (VIP) prevents neurotoxicity in neuronal cultures: Relevance to neuroprotection in Parkinson's disease. Brain Res. 854(1-2):257-262; 2000.
-
(2000)
Relevance to Neuroprotection In Parkinson's Disease. Brain Res
, vol.854
, Issue.1-2
, pp. 257-262
-
-
Offen, D.1
Sherki, Y.2
Melamed, E.3
Fridkin, M.4
Brenneman, D.E.5
Gozes, I.6
-
107
-
-
0030248408
-
Development of neuronal precursor cells and functional postmitotic neurons from embryonic stem cells in vitro
-
Okabe, S.; Forsberg-Nilsson, K.; Spiro, A. C.; Segal, M.; McKay, R. D. Development of neuronal precursor cells and functional postmitotic neurons from embryonic stem cells in vitro. Mech. Dev. 59(1):89-102; 1996.
-
(1996)
Mech. Dev
, vol.59
, Issue.1
, pp. 89-102
-
-
Okabe, S.1
Forsberg-Nilsson, K.2
Spiro, A.C.3
Segal, M.4
McKay, R.D.5
-
108
-
-
0034614415
-
Constitutive phosphorylation of the Parkinson's disease associated α-synuclein
-
Okochi, M.; Walter, J.; Koyama, A.; Nakajo, S.; Baba, M.; Iwatsubo, T.; Meijer, L.; Kahle, P. J.; Haass, C. Constitutive phosphorylation of the Parkinson's disease associated α-synuclein. J. Biol. Chem. 275(1):390-397; 2000.
-
(2000)
J. Biol. Chem
, vol.275
, Issue.1
, pp. 390-397
-
-
Okochi, M.1
Walter, J.2
Koyama, A.3
Nakajo, S.4
Baba, M.5
Iwatsubo, T.6
Meijer, L.7
Kahle, P.J.8
Haass, C.9
-
109
-
-
3042541863
-
G209A mutant α-synuclein expression specifically enhances dopamine induced oxidative damage
-
Orth, M.; Tabrizi, S. J.; Tomlinson, C.; Messmer, K.; Korlipara, L. V.; Schapira, A. H.; Cooper, J. M. G209A mutant α-synuclein expression specifically enhances dopamine induced oxidative damage. Neurochem. Int. 45(5):669-676; 2004.
-
(2004)
Neurochem. Int
, vol.45
, Issue.5
, pp. 669-676
-
-
Orth, M.1
Tabrizi, S.J.2
Tomlinson, C.3
Messmer, K.4
Korlipara, L.V.5
Schapira, A.H.6
Cooper, J.M.7
-
110
-
-
34547599329
-
Sirtuin 2 inhibitors rescue α-synuclein-mediated toxicity in models of Parkinson's disease
-
Outeiro, T. F.; Kontopoulos, E.; Altmann, S. M.; Kufareva, I.; Strathearn, K. E.; Amore, A. M.; Volk, C. B.; Maxwell, M. M.; Rochet, J. C.; McLean, P. J.; Young, A. B.; Abagyan, R.; Feany, M. B.; Hyman, B. T.; Kazantsev, A. G. Sirtuin 2 inhibitors rescue α-synuclein-mediated toxicity in models of Parkinson's disease. Science 317(5837):516-519; 2007.
-
(2007)
Science
, vol.317
, Issue.5837
, pp. 516-519
-
-
Outeiro, T.F.1
Kontopoulos, E.2
Altmann, S.M.3
Kufareva, I.4
Strathearn, K.E.5
Amore, A.M.6
Volk, C.B.7
Maxwell, M.M.8
Rochet, J.C.9
McLean, P.J.10
Young, A.B.11
Abagyan, R.12
Feany, M.B.13
Hyman, B.T.14
Kazantsev, A.G.15
-
111
-
-
31344439221
-
LRRK2 G2019S as a cause of Parkinson's disease in Ashkenazi Jews
-
Ozelius, L. J.; Senthil, G.; Saunders-Pullman, R.; Ohmann, E.; Deligtisch, A.; Tagliati, M.; Hunt, A. L.; Klein, C.; Henick, B.; Hailpern, S. M.; Lipton, R. B.; Soto-Valencia, J.; Risch, N.; Bressman, S. B. LRRK2 G2019S as a cause of Parkinson's disease in Ashkenazi Jews. N. Engl. J. Med. 354(4):424-425; 2006.
-
(2006)
N. Engl. J. Med
, vol.354
, Issue.4
, pp. 424-425
-
-
Ozelius, L.J.1
Senthil, G.2
Saunders-Pullman, R.3
Ohmann, E.4
Deligtisch, A.5
Tagliati, M.6
Hunt, A.L.7
Klein, C.8
Henick, B.9
Hailpern, S.M.10
Lipton, R.B.11
Soto-Valencia, J.12
Risch, N.13
Bressman, S.B.14
-
112
-
-
33749519563
-
Mutations in DJ-1 are rare in familial Parkinson disease
-
Pankratz, N.; Pauciulo, M. W.; Elsaesser, V. E.; Marek, D. K.; Halter, C. A.; Wojcieszek, J.; Rudolph, A.; Shults, C. W.; Foroud, T.; Nichols, W. C. Mutations in DJ-1 are rare in familial Parkinson disease. Neurosci. Lett. 408(3):209-213; 2006.
-
(2006)
Neurosci. Lett
, vol.408
, Issue.3
, pp. 209-213
-
-
Pankratz, N.1
Pauciulo, M.W.2
Elsaesser, V.E.3
Marek, D.K.4
Halter, C.A.5
Wojcieszek, J.6
Rudolph, A.7
Shults, C.W.8
Foroud, T.9
Nichols, W.C.10
-
113
-
-
0031822077
-
A review of Lewy body disease, an emerging concept of cortical dementia
-
Papka, M.; Rubio, A.; Schiffer, R. B. A review of Lewy body disease, an emerging concept of cortical dementia. J. Neuropsychiatry Clin. Neurosci. 10(3):267-279; 1998.
-
(1998)
J. Neuropsychiatry Clin. Neurosci
, vol.10
, Issue.3
, pp. 267-279
-
-
Papka, M.1
Rubio, A.2
Schiffer, R.B.3
-
114
-
-
51849088599
-
Mesenchymal stem cells therapy exerts neuroprotection in a progressive animal model of Parkinson's disease
-
Park, H. J.; Lee, P. H.; Bang, O. Y.; Lee, G.; Ahn, Y. H. Mesenchymal stem cells therapy exerts neuroprotection in a progressive animal model of Parkinson's disease. J. Neurochem. 107(1):141-151; 2008.
-
(2008)
J. Neurochem
, vol.107
, Issue.1
, pp. 141-151
-
-
Park, H.J.1
Lee, P.H.2
Bang, O.Y.3
Lee, G.4
Ahn, Y.H.5
-
115
-
-
33745602748
-
Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin
-
Park, J.; Lee, S. B.; Lee, S.; Kim, Y.; Song, S.; Kim, S.; Bae, E.; Kim, J.; Shong, M.; Kim, J. M.; Chung, J. Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin. Nature 441(7097):1157-1161; 2006.
-
(2006)
Nature
, vol.441
, Issue.7097
, pp. 1157-1161
-
-
Park, J.1
Lee, S.B.2
Lee, S.3
Kim, Y.4
Song, S.5
Kim, S.6
Bae, E.7
Kim, J.8
Shong, M.9
Kim, J.M.10
Chung, J.11
-
116
-
-
33947505619
-
Aggregated α-synuclein mediates dopaminergic neurotoxicity in vivo
-
Periquet, M.; Fulga, T.; Myllykangas, L.; Schlossmacher, M. G.; Feany, M. B. Aggregated α-synuclein mediates dopaminergic neurotoxicity in vivo. J. Neurosci. 27(12): 3338-3346; 2007.
-
(2007)
J. Neurosci
, vol.27
, Issue.12
, pp. 3338-3346
-
-
Periquet, M.1
Fulga, T.2
Myllykangas, L.3
Schlossmacher, M.G.4
Feany, M.B.5
-
117
-
-
0018778418
-
Brain grafts reduce motor abnormalities produced by destruction of nigrostriatal dopamine system
-
Perlow, M. J.; Freed, W. J.; Hoffer, B. J.; Seiger, A.; Olson, L.; Wyatt, R. J. Brain grafts reduce motor abnormalities produced by destruction of nigrostriatal dopamine system. Science 204(4393):643-647; 1979.
-
(1979)
Science
, vol.204
, Issue.4393
, pp. 643-647
-
-
Perlow, M.J.1
Freed, W.J.2
Hoffer, B.J.3
Seiger, A.4
Olson, L.5
Wyatt, R.J.6
-
118
-
-
0033491121
-
Dopamine release from nigral transplants visualized in vivo in a Parkinson's patient
-
Piccini, P.; Brooks, D. J.; Bjorklund, A.; Gunn, R. N.; Grasby, P. M.; Rimoldi, O.; Brundin, P.; Hagell, P.; Rehncrona, S.; Widner, H.; Lindvall, O. Dopamine release from nigral transplants visualized in vivo in a Parkinson's patient. Nat. Neurosci. 2(12):1137-1140; 1999.
-
(1999)
Nat. Neurosci
, vol.2
, Issue.12
, pp. 1137-1140
-
-
Piccini, P.1
Brooks, D.J.2
Bjorklund, A.3
Gunn, R.N.4
Grasby, P.M.5
Rimoldi, O.6
Brundin, P.7
Hagell, P.8
Rehncrona, S.9
Widner, H.10
Lindvall, O.11
-
119
-
-
0030744876
-
Mutation in the α-synuclein gene identified in families with Parkinson's disease
-
Polymeropoulos, M. H.; Lavedan, C.; Leroy, E.; Ide, S. E.; Dehejia, A.; Dutra, A.; Pike, B.; Root, H.; Rubenstein, J.; Boyer, R.; Stenroos, E. S.; Chandrasekharappa, S.; Athanassiadou, A.; Papapetropoulos, T.; Johnson, W. G.; Lazzarini, A. M.; Duvoisin, R. C.; Di Iorio, G.; Golbe, L. I.; Nussbaum, R. L. Mutation in the α-synuclein gene identified in families with Parkinson's disease. Science 276(5321):2045-2047; 1997.
-
(1997)
Science
, vol.276
, Issue.5321
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
Ide, S.E.4
Dehejia, A.5
Dutra, A.6
Pike, B.7
Root, H.8
Rubenstein, J.9
Boyer, R.10
Stenroos, E.S.11
Chandrasekharappa, S.12
Athanassiadou, A.13
Papapetropoulos, T.14
Johnson, W.G.15
Lazzarini, A.M.16
Duvoisin, R.C.17
Di Iorio, G.18
Golbe, L.I.19
Nussbaum, R.L.20
more..
-
120
-
-
39449088321
-
The PINK1/Parkin pathway regulates mitochondrial morphology
-
Poole, A. C.; Thomas, R. E.; Andrews, L. A.; McBride, H. M.; Whitworth, A. J.; Pallanck, L. J. The PINK1/Parkin pathway regulates mitochondrial morphology. Proc. Natl. Acad. Sci. USA 105(5):1638-1643; 2008.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, Issue.5
, pp. 1638-1643
-
-
Poole, A.C.1
Thomas, R.E.2
Andrews, L.A.3
McBride, H.M.4
Whitworth, A.J.5
Pallanck, L.J.6
-
121
-
-
34547127902
-
PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1
-
Pridgeon, J. W.; Olzmann, J. A.; Chin, L. S.; Li, L. PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1. PLoS Biol. 5(7):e172; 2007.
-
(2007)
PLoS Biol
, vol.5
, Issue.7
-
-
Pridgeon, J.W.1
Olzmann, J.A.2
Chin, L.S.3
Li, L.4
-
122
-
-
0034947602
-
Environmental risk factors and Parkinson's disease: A meta-analysis
-
Priyadarshi, A.; Khuder, S. A.; Schaub, E. A.; Priyadarshi, S. S. Environmental risk factors and Parkinson's disease: A meta-analysis. Environ. Res. 86(2):122-127; 2001.
-
(2001)
Environ. Res
, vol.86
, Issue.2
, pp. 122-127
-
-
Priyadarshi, A.1
Khuder, S.A.2
Schaub, E.A.3
Priyadarshi, S.S.4
-
123
-
-
0034714204
-
Synucleins are a novel class of substrates for G proteincoupled receptor kinases
-
Pronin, A. N.; Morris, A. J.; Surguchov, A.; Benovic, J. L. Synucleins are a novel class of substrates for G proteincoupled receptor kinases. J. Biol. Chem. 275(34):26515-26522; 2000.
-
(2000)
J. Biol. Chem
, vol.275
, Issue.34
, pp. 26515-26522
-
-
Pronin, A.N.1
Morris, A.J.2
Surguchov, A.3
Benovic, J.L.4
-
124
-
-
67651008224
-
Lrrk2 phosphorylates a synuclein at serine 129: Parkinson disease implications
-
Qing, H.; Wong, W.; McGeer, E. G.; McGeer, P. L. Lrrk2 phosphorylates a synuclein at serine 129: Parkinson disease implications. Biochem. Biophys. Res. Commun. 387(1):149-152; 2009.
-
(2009)
Biochem. Biophys. Res. Commun
, vol.387
, Issue.1
, pp. 149-152
-
-
Qing, H.1
Wong, W.2
McGeer, E.G.3
McGeer, P.L.4
-
125
-
-
33749133430
-
Hereditary parkinsonism with dementia is caused by mutations in ATP13A2, encoding a lysosomal type 5 P-type ATPase
-
Ramirez, A.; Heimbach, A.; Grundemann, J.; Stiller, B.; Hampshire, D.; Cid, L. P.; Goebel, I.; Mubaidin, A. F.; Wriekat, A. L.; Roeper, J.; Al-Din, A.; Hillmer, A. M.; Karsak, M.; Liss, B.; Woods, C. G.; Behrens, M. I.; Kubisch, C. Hereditary parkinsonism with dementia is caused by mutations in ATP13A2, encoding a lysosomal type 5 P-type ATPase. Nat. Genet. 38(10):1184-1191; 2006.
-
(2006)
Nat. Genet
, vol.38
, Issue.10
, pp. 1184-1191
-
-
Ramirez, A.1
Heimbach, A.2
Grundemann, J.3
Stiller, B.4
Hampshire, D.5
Cid, L.P.6
Goebel, I.7
Mubaidin, A.F.8
Wriekat, A.L.9
Roeper, J.10
Al-Din, A.11
Hillmer, A.M.12
Karsak, M.13
Liss, B.14
Woods, C.G.15
Behrens, M.I.16
Kubisch, C.17
-
126
-
-
72149101615
-
Initial clinical manifestations of Parkinson's disease: Features and pathophysiological mechanisms
-
Rodriguez-Oroz, M. C.; Jahanshahi, M.; Krack, P.; Litvan, I.; Macias, R.; Bezard, E.; Obeso, J. A. Initial clinical manifestations of Parkinson's disease: Features and pathophysiological mechanisms. Lancet Neurol. 8(12):1128-1139; 2009.
-
(2009)
Lancet Neurol
, vol.8
, Issue.12
, pp. 1128-1139
-
-
Rodriguez-Oroz, M.C.1
Jahanshahi, M.2
Krack, P.3
Litvan, I.4
Macias, R.5
Bezard, E.6
Obeso, J.A.7
-
127
-
-
3042573271
-
Growth factor treatment of neurodegenerative disorders: New developments pave the way for clinical success
-
Rosenblad, C. Growth factor treatment of neurodegenerative disorders: New developments pave the way for clinical success. IDrugs 7(3):243-248; 2004.
-
(2004)
IDrugs
, vol.7
, Issue.3
, pp. 243-248
-
-
Rosenblad, C.1
-
128
-
-
77956188265
-
Differentiation of non-mesencephalic neural stem cells towards dopaminergic neurons
-
Rossler, R.; Boddeke, E.; Copray, S. Differentiation of non-mesencephalic neural stem cells towards dopaminergic neurons. Neuroscience 170(2):417-428; 2010.
-
(2010)
Neuroscience
, vol.170
, Issue.2
, pp. 417-428
-
-
Rossler, R.1
Boddeke, E.2
Copray, S.3
-
129
-
-
33750706917
-
Functional engraftment of human ES cellderived dopaminergic neurons enriched by coculture with telomerase-immortalized midbrain astrocytes
-
Roy, N. S.; Cleren, C.; Singh, S. K.; Yang, L.; Beal, M. F.; Goldman, S. A. Functional engraftment of human ES cellderived dopaminergic neurons enriched by coculture with telomerase-immortalized midbrain astrocytes. Nat. Med. 12(11):1259-1268; 2006.
-
(2006)
Nat. Med
, vol.12
, Issue.11
, pp. 1259-1268
-
-
Roy, N.S.1
Cleren, C.2
Singh, S.K.3
Yang, L.4
Beal, M.F.5
Goldman, S.A.6
-
130
-
-
2542596183
-
Parkinson's disease
-
Samii, A.; Nutt, J. G.; Ransom, B. R. Parkinson's disease. Lancet 363(9423):1783-1793; 2004.
-
(2004)
Lancet
, vol.363
, Issue.9423
, pp. 1783-1793
-
-
Samii, A.1
Nutt, J.G.2
Ransom, B.R.3
-
132
-
-
0037104723
-
An in vitro model of Parkinson's disease: Linking mitochondrial impairment to altered α-synuclein metabolism and oxidative damage
-
Sherer, T. B.; Betarbet, R.; Stout, A. K.; Lund, S.; Baptista, M.; Panov, A. V.; Cookson, M. R.; Greenamyre, J. T. An in vitro model of Parkinson's disease: Linking mitochondrial impairment to altered α-synuclein metabolism and oxidative damage. J Neurosci. 22(16):7006-7015; 2002.
-
(2002)
J Neurosci
, vol.22
, Issue.16
, pp. 7006-7015
-
-
Sherer, T.B.1
Betarbet, R.2
Stout, A.K.3
Lund, S.4
Baptista, M.5
Panov, A.V.6
Cookson, M.R.7
Greenamyre, J.T.8
-
133
-
-
0033933048
-
Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase
-
Shimura, H.; Hattori, N.; Kubo, S.; Mizuno, Y.; Asakawa, S.; Minoshima, S.; Shimizu, N.; Iwai, K.; Chiba, T.; Tanaka, K.; Suzuki, T. Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase. Nat. Genet. 25(3):302-305; 2000.
-
(2000)
Nat. Genet
, vol.25
, Issue.3
, pp. 302-305
-
-
Shimura, H.1
Hattori, N.2
Kubo, S.3
Mizuno, Y.4
Asakawa, S.5
Minoshima, S.6
Shimizu, N.7
Iwai, K.8
Chiba, T.9
Tanaka, K.10
Suzuki, T.11
-
134
-
-
0034728281
-
Expression patterns of α-synuclein in human hematopoietic cells and in drosophila at different developmental stages
-
Shin, E. C.; Cho, S. E.; Lee, D. K.; Hur, M. W.; Paik, S. R.; Park, J. H.; Kim, J. Expression patterns of α-synuclein in human hematopoietic cells and in Drosophila at different developmental stages. Mol. Cells 10(1):65-70; 2000.
-
(2000)
Mol. Cells
, vol.10
, Issue.1
, pp. 65-70
-
-
Shin, E.C.1
Cho, S.E.2
Lee, D.K.3
Hur, M.W.4
Paik, S.R.5
Park, J.H.6
Kim, J.7
-
135
-
-
44449112128
-
Genome-wide linkage analysis of a Parkinsonianpyramidal syndrome pedigree by 500 K SNP arrays
-
Shojaee, S.; Sina, F.; Banihosseini, S. S.; Kazemi, M. H.; Kalhor, R.; Shahidi, G. A.; Fakhrai-Rad, H.; Ronaghi, M.; Elahi, E. Genome-wide linkage analysis of a Parkinsonianpyramidal syndrome pedigree by 500 K SNP arrays. Am. J. Hum. Genet. 82(6):1375-1384; 2008.
-
(2008)
Am. J. Hum. Genet
, vol.82
, Issue.6
, pp. 1375-1384
-
-
Shojaee, S.1
Sina, F.2
Banihosseini, S.S.3
Kazemi, M.H.4
Kalhor, R.5
Shahidi, G.A.6
Fakhrai-Rad, H.7
Ronaghi, M.8
Elahi, E.9
-
136
-
-
77953485582
-
Synphilin-1 attenuates neuronal degeneration in the A53T α-synuclein transgenic mouse model
-
Smith, W. W.; Liu, Z.; Liang, Y.; Masuda, N.; Swing, D. A.; Jenkins, N. A.; Copeland, N. G.; Troncoso, J. C.; Pletnikov, M.; Dawson, T. M.; Martin, L. J.; Moran, T. H.; Lee, M. K.; Borchelt, D. R.; Ross, C. A. Synphilin-1 attenuates neuronal degeneration in the A53T α-synuclein transgenic mouse model. Hum. Mol. Genet. 19(11):2087-2098; 2010.
-
(2010)
Hum. Mol. Genet
, vol.19
, Issue.11
, pp. 2087-2098
-
-
Smith, W.W.1
Liu, Z.2
Liang, Y.3
Masuda, N.4
Swing, D.A.5
Jenkins, N.A.6
Copeland, N.G.7
Troncoso, J.C.8
Pletnikov, M.9
Dawson, T.M.10
Martin, L.J.11
Moran, T.H.12
Lee, M.K.13
Borchelt, D.R.14
Ross, C.A.15
-
137
-
-
61349100729
-
Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors
-
Soldner, F.; Hockemeyer, D.; Beard, C.; Gao, Q.; Bell, G. W.; Cook, E. G.; Hargus, G.; Blak, A.; Cooper, O.; Mitalipova, M.; Isacson, O.; Jaenisch, R. Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors. Cell 136(5):964-977; 2009.
-
(2009)
Cell
, vol.136
, Issue.5
, pp. 964-977
-
-
Soldner, F.1
Hockemeyer, D.2
Beard, C.3
Gao, Q.4
Bell, G.W.5
Cook, E.G.6
Hargus, G.7
Blak, A.8
Cooper, O.9
Mitalipova, M.10
Isacson, O.11
Jaenisch, R.12
-
138
-
-
0030882856
-
α-Synuclein in Lewy bodies
-
Spillantini, M. G.; Schmidt, M. L.; Lee, V. M.; Trojanowski, J. Q.; Jakes, R.; Goedert, M. α-Synuclein in Lewy bodies. Nature 388(6645):839-840; 1997.
-
(1997)
Nature
, vol.388
, Issue.6645
, pp. 839-840
-
-
Spillantini, M.G.1
Schmidt, M.L.2
Lee, V.M.3
Trojanowski, J.Q.4
Jakes, R.5
Goedert, M.6
-
139
-
-
0031265935
-
Longterm survival of human central nervous system progenitor cells transplanted into a rat model of Parkinson's disease
-
Svendsen, C. N.; Caldwell, M. A.; Shen, J.; ter Borg, M. G.; Rosser, A. E.; Tyers, P.; Karmiol, S.; Dunnett, S. B. Longterm survival of human central nervous system progenitor cells transplanted into a rat model of Parkinson's disease. Exp. Neurol. 148(1):135-146; 1997.
-
(1997)
Exp. Neurol
, vol.148
, Issue.1
, pp. 135-146
-
-
Svendsen, C.N.1
Caldwell, M.A.2
Shen, J.3
ter Borg, M.G.4
Rosser, A.E.5
Tyers, P.6
Karmiol, S.7
Dunnett, S.B.8
-
140
-
-
0032409396
-
A new method for the rapid and long term growth of human neural precursor cells
-
Svendsen, C. N.; ter Borg, M. G.; Armstrong, R. J.; Rosser, A. E.; Chandran, S.; Ostenfeld, T.; Caldwell, M. A. A new method for the rapid and long term growth of human neural precursor cells. J. Neurosci. Methods 85(2):141-152; 1998.
-
(1998)
J. Neurosci. Methods
, vol.85
, Issue.2
, pp. 141-152
-
-
Svendsen, C.N.1
ter Borg, M.G.2
Armstrong, R.J.3
Rosser, A.E.4
Chandran, S.5
Ostenfeld, T.6
Caldwell, M.A.7
-
141
-
-
0032845909
-
Viral etiology for Parkinson's disease-a possible role of influenza A virus infection
-
Takahashi, M.; Yamada, T. Viral etiology for Parkinson's disease-a possible role of influenza A virus infection. Jpn. J. Infect. Dis. 52(3):89-98; 1999.
-
(1999)
Jpn. J. Infect. Dis
, vol.52
, Issue.3
, pp. 89-98
-
-
Takahashi, M.1
Yamada, T.2
-
142
-
-
0038389675
-
Parkin and endoplasmic reticulum stress
-
Takahashi, R.; Imai, Y.; Hattori, N.; Mizuno, Y. Parkin and endoplasmic reticulum stress. Ann. N. Y. Acad. Sci. 991:101-106; 2003.
-
(2003)
Ann. N. Y. Acad. Sci
, vol.991
, pp. 101-106
-
-
Takahashi, R.1
Imai, Y.2
Hattori, N.3
Mizuno, Y.4
-
143
-
-
77649316334
-
PLA2G6 mutations and Parkinson's disease
-
Tan, E. K.; Ho, P.; Tan, L.; Prakash, K. M.; Zhao, Y. PLA2G6 mutations and Parkinson's disease. Ann. Neurol. 67(1):148; 2010.
-
(2010)
Ann. Neurol
, vol.67
, Issue.1
, pp. 148
-
-
Tan, E.K.1
Ho, P.2
Tan, L.3
Prakash, K.M.4
Zhao, Y.5
-
144
-
-
0037208691
-
Is the cause of Parkinson's disease environmental or hereditary? Evidence from twin studies
-
Tanner, C. M. Is the cause of Parkinson's disease environmental or hereditary? Evidence from twin studies. Adv. Neurol. 91:133-142; 2003.
-
(2003)
Adv. Neurol
, vol.91
, pp. 133-142
-
-
Tanner, C.M.1
-
145
-
-
37349004102
-
Parkinson's disease
-
Thomas, B.; Beal, M. F. Parkinson's disease. Hum. Mol. Genet. 16 (Spec No. 2):R183-R194; 2007.
-
(2007)
Hum. Mol. Genet
, vol.16
, Issue.2
-
-
Thomas, B.1
Beal, M.F.2
-
146
-
-
33144474684
-
Clonal amniotic fluid-derived stem cells express characteristics of both mesenchymal and neural stem cells
-
Tsai, M. S.; Hwang, S. M.; Tsai, Y. L.; Cheng, F. C.; Lee, J. L.; Chang, Y. J. Clonal amniotic fluid-derived stem cells express characteristics of both mesenchymal and neural stem cells. Biol. Reprod. 74(3):545-551; 2006.
-
(2006)
Biol. Reprod
, vol.74
, Issue.3
, pp. 545-551
-
-
Tsai, M.S.1
Hwang, S.M.2
Tsai, Y.L.3
Cheng, F.C.4
Lee, J.L.5
Chang, Y.J.6
-
147
-
-
2442668926
-
Hereditary early-onset Parkinson's disease caused by mutations in PINK1
-
Valente, E. M.; Abou-Sleiman, P. M.; Caputo, V.; Muqit, M. M.; Harvey, K.; Gispert, S.; Ali, Z.; Del Turco, D.; Bentivoglio, A. R.; Healy, D. G.; Albanese, A.; Nussbaum, R.; Gonzalez-Maldonado, R.; Deller, T.; Salvi, S.; Cortelli, P.; Gilks, W. P.; Latchman, D. S.; Harvey, R. J.; Dallapiccola, B.; Auburger, G.; Wood, N. W. Hereditary early-onset Parkinson's disease caused by mutations in PINK1. Science 304(5674):1158-1160; 2004.
-
(2004)
Science
, vol.304
, Issue.5674
, pp. 1158-1160
-
-
Valente, E.M.1
Abou-Sleiman, P.M.2
Caputo, V.3
Muqit, M.M.4
Harvey, K.5
Gispert, S.6
Ali, Z.7
Del Turco, D.8
Bentivoglio, A.R.9
Healy, D.G.10
Albanese, A.11
Nussbaum, R.12
Gonzalez-Maldonado, R.13
Deller, T.14
Salvi, S.15
Cortelli, P.16
Gilks, W.P.17
Latchman, D.S.18
Harvey, R.J.19
Dallapiccola, B.20
Auburger, G.21
Wood, N.W.22
more..
-
148
-
-
0037675042
-
Incidence of Parkinson's disease: Variation by age, gender, and race/ethnicity
-
Van Den Eeden, S. K.; Tanner, C. M.; Bernstein, A. L.; Fross, R. D.; Leimpeter, A.; Bloch, D. A.; Nelson, L. M. Incidence of Parkinson's disease: Variation by age, gender, and race/ethnicity. Am. J. Epidemiol. 157(11):1015-1022; 2003.
-
(2003)
Am. J. Epidemiol
, vol.157
, Issue.11
, pp. 1015-1022
-
-
Van Den Eeden, S.K.1
Tanner, C.M.2
Bernstein, A.L.3
Fross, R.D.4
Leimpeter, A.5
Bloch, D.A.6
Nelson, L.M.7
-
149
-
-
78650754334
-
Culture media for the differentiation of mesenchymal stromal cells
-
Vater, C.; Kasten, P.; Stiehler, M. Culture media for the differentiation of mesenchymal stromal cells. Acta Biomater. 7(2):463-477; 2011.
-
(2011)
Acta Biomater
, vol.7
, Issue.2
, pp. 463-477
-
-
Vater, C.1
Kasten, P.2
Stiehler, M.3
-
150
-
-
0034929304
-
Deep brain stimulation in the treatment of severe dystonia
-
Vercueil, L.; Pollak, P.; Fraix, V.; Caputo, E.; Moro, E.; Benazzouz, A.; Xie, J.; Koudsie, A.; Benabid, A. L. Deep brain stimulation in the treatment of severe dystonia. J. Neurol. 248(8):695-700; 2001.
-
(2001)
J. Neurol
, vol.248
, Issue.8
, pp. 695-700
-
-
Vercueil, L.1
Pollak, P.2
Fraix, V.3
Caputo, E.4
Moro, E.5
Benazzouz, A.6
Xie, J.7
Koudsie, A.8
Benabid, A.L.9
-
151
-
-
43049164497
-
Deep brain stimulation for Parkinson's disease: Prevalence of adverse events and need for standardized reporting
-
Videnovic, A.; Metman, L. V. Deep brain stimulation for Parkinson's disease: Prevalence of adverse events and need for standardized reporting. Mov. Disord. 23(3):343-349; 2008.
-
(2008)
Mov. Disord
, vol.23
, Issue.3
, pp. 343-349
-
-
Videnovic, A.1
Metman, L.V.2
-
152
-
-
77649162059
-
Direct conversion of fibroblasts to functional neurons by defined factors
-
Vierbuchen, T.; Ostermeier, A.; Pang, Z. P.; Kokubu, Y.; Sudhof, T. C.; Wernig, M. Direct conversion of fibroblasts to functional neurons by defined factors. Nature 463(7284):1035-1041; 2010.
-
(2010)
Nature
, vol.463
, Issue.7284
, pp. 1035-1041
-
-
Vierbuchen, T.1
Ostermeier, A.2
Pang, Z.P.3
Kokubu, Y.4
Sudhof, T.C.5
Wernig, M.6
-
153
-
-
0036938071
-
Immunocytochemical localization of synphilin-1, an α-synucleinassociated protein, in neurodegenerative disorders
-
Wakabayashi, K.; Engelender, S.; Tanaka, Y.; Yoshimoto, M.; Mori, F.; Tsuji, S.; Ross, C. A.; Takahashi, H. Immunocytochemical localization of synphilin-1, an α-synucleinassociated protein, in neurodegenerative disorders. Acta Neuropathol. 103(3):209-214; 2002.
-
(2002)
Acta Neuropathol
, vol.103
, Issue.3
, pp. 209-214
-
-
Wakabayashi, K.1
Engelender, S.2
Tanaka, Y.3
Yoshimoto, M.4
Mori, F.5
Tsuji, S.6
Ross, C.A.7
Takahashi, H.8
-
154
-
-
0034085796
-
Synphilin-1 is present in Lewy bodies in Parkinson's disease
-
Wakabayashi, K.; Engelender, S.; Yoshimoto, M.; Tsuji, S.; Ross, C. A.; Takahashi, H. Synphilin-1 is present in Lewy bodies in Parkinson's disease. Ann. Neurol. 47(4):521-523; 2000.
-
(2000)
Ann. Neurol
, vol.47
, Issue.4
, pp. 521-523
-
-
Wakabayashi, K.1
Engelender, S.2
Yoshimoto, M.3
Tsuji, S.4
Ross, C.A.5
Takahashi, H.6
-
155
-
-
79251503950
-
Cell transplantation and gene therapy in Parkinson's disease
-
Wakeman, D. R.; Dodiya, H. B.; Kordower, J. H. Cell transplantation and gene therapy in Parkinson's disease. Mt. Sinai J. Med. 78(1):126-158; 2011.
-
(2011)
Mt. Sinai J. Med
, vol.78
, Issue.1
, pp. 126-158
-
-
Wakeman, D.R.1
Dodiya, H.B.2
Kordower, J.H.3
-
156
-
-
77949912959
-
Novel GIGYF2 gene variants in patients with Parkinson's disease in Chinese population
-
Wang, L.; Guo, J. F.; Zhang, W. W.; Xu, Q.; Zuo, X.; Shi, C. H.; Luo, L. Z.; Liu, J.; Hu, L.; Hu, Y. C.; She, L.; Jiang, H.; Yan, X. X.; Xia, K.; Pan, Q.; Tang, B. S. Novel GIGYF2 gene variants in patients with Parkinson's disease in Chinese population. Neurosci. Lett. 473(2):131-135; 2010.
-
(2010)
Neurosci. Lett
, vol.473
, Issue.2
, pp. 131-135
-
-
Wang, L.1
Guo, J.F.2
Zhang, W.W.3
Xu, Q.4
Zuo, X.5
Shi, C.H.6
Luo, L.Z.7
Liu, J.8
Hu, L.9
Hu, Y.C.10
She, L.11
Jiang, H.12
Yan, X.X.13
Xia, K.14
Pan, Q.15
Tang, B.S.16
-
157
-
-
43249108653
-
Specificity and regulation of casein kinase-mediated phosphorylation of α-synuclein
-
Waxman, E. A.; Giasson, B. I. Specificity and regulation of casein kinase-mediated phosphorylation of α-synuclein. J. Neuropathol. Exp. Neurol. 67(5):402-416; 2008.
-
(2008)
J. Neuropathol. Exp. Neurol
, vol.67
, Issue.5
, pp. 402-416
-
-
Waxman, E.A.1
Giasson, B.I.2
-
158
-
-
79957933246
-
Cognitive outcome and reliable change indices two years following bilateral subthalamic nucleus deep brain stimulation
-
Williams, A. E.; Arzola, G. M.; Strutt, A. M.; Simpson, R.; Jankovic, J.; York, M. K. Cognitive outcome and reliable change indices two years following bilateral subthalamic nucleus deep brain stimulation. Parkinsonism Relat Disord. 17(5):321-327; 2011.
-
(2011)
Parkinsonism Relat Disord
, vol.17
, Issue.5
, pp. 321-327
-
-
Williams, A.E.1
Arzola, G.M.2
Strutt, A.M.3
Simpson, R.4
Jankovic, J.5
York, M.K.6
-
159
-
-
79953794756
-
VEGF-expressing human umbilical cord mesenchymal stem cells, an improved therapy strategy for Parkinson's disease
-
Xiong, N.; Zhang, Z.; Huang, J.; Chen, C.; Zhang, Z.; Jia, M.; Xiong, J.; Liu, X.; Wang, F.; Cao, X.; Liang, Z.; Sun, S.; Lin, Z.; Wang, T. VEGF-expressing human umbilical cord mesenchymal stem cells, an improved therapy strategy for Parkinson's disease. Gene Ther. 18(4):394-402; 2010.
-
(2010)
Gene Ther
, vol.18
, Issue.4
, pp. 394-402
-
-
Xiong, N.1
Zhang, Z.2
Huang, J.3
Chen, C.4
Zhang, Z.5
Jia, M.6
Xiong, J.7
Liu, X.8
Wang, F.9
Cao, X.10
Liang, Z.11
Sun, S.12
Lin, Z.13
Wang, T.14
-
160
-
-
58549119203
-
Effects of UCH-L1 on α-synuclein overexpression mouse model of Parkinson's disease
-
Yasuda, T.; Nihira, T.; Ren, Y. R.; Cao, X. Q.; Wada, K.; Setsuie, R.; Kabuta, T.; Wada, K.; Hattori, N.; Mizuno, Y.; Mochizuki, H. Effects of UCH-L1 on α-synuclein overexpression mouse model of Parkinson's disease. J. Neurochem. 108(4):932-944; 2009.
-
(2009)
J. Neurochem
, vol.108
, Issue.4
, pp. 932-944
-
-
Yasuda, T.1
Nihira, T.2
Ren, Y.R.3
Cao, X.Q.4
Wada, K.5
Setsuie, R.6
Kabuta, T.7
Wada, K.8
Hattori, N.9
Mizuno, Y.10
Mochizuki, H.11
-
161
-
-
0032577445
-
FGF and Shh signals control dopaminergic and serotonergic cell fate in the anterior neural plate
-
Ye, W.; Shimamura, K.; Rubenstein, J. L.; Hynes, M. A.; Rosenthal, A. FGF and Shh signals control dopaminergic and serotonergic cell fate in the anterior neural plate. Cell 93(5):755-766; 1998.
-
(1998)
Cell
, vol.93
, Issue.5
, pp. 755-766
-
-
Ye, W.1
Shimamura, K.2
Rubenstein, J.L.3
Hynes, M.A.4
Rosenthal, A.5
-
162
-
-
0345357664
-
Down regulation of DJ-1 enhances cell death by oxidative stress, ER stress, and proteasome inhibition
-
Yokota, T.; Sugawara, K.; Ito, K.; Takahashi, R.; Ariga, H.; Mizusawa, H. Down regulation of DJ-1 enhances cell death by oxidative stress, ER stress, and proteasome inhibition. Biochem. Biophys. Res. Commun. 312(4):1342-1348; 2003.
-
(2003)
Biochem. Biophys. Res. Commun
, vol.312
, Issue.4
, pp. 1342-1348
-
-
Yokota, T.1
Sugawara, K.2
Ito, K.3
Takahashi, R.4
Ariga, H.5
Mizusawa, H.6
-
163
-
-
77958570876
-
Phenotypic spectrum of patients with PLA2G6 mutation and PARK14-linked parkinsonism
-
Yoshino, H.; Tomiyama, H.; Tachibana, N.; Ogaki, K.; Li, Y.; Funayama, M.; Hashimoto, T.; Takashima, S.; Hattori, N. Phenotypic spectrum of patients with PLA2G6 mutation and PARK14-linked parkinsonism. Neurology 75(15):1356-1361; 2010.
-
(2010)
Neurology
, vol.75
, Issue.15
, pp. 1356-1361
-
-
Yoshino, H.1
Tomiyama, H.2
Tachibana, N.3
Ogaki, K.4
Li, Y.5
Funayama, M.6
Hashimoto, T.7
Takashima, S.8
Hattori, N.9
-
164
-
-
36749043230
-
Induced pluripotent stem cell lines derived from human somatic cells
-
Yu, J.; Vodyanik, M. A.; Smuga-Otto, K.; Antosiewicz- Bourget, J.; Frane, J. L.; Tian, S.; Nie, J.; Jonsdottir, G. A.; Ruotti, V.; Stewart, R.; Slukvin, I. I.; Thomson, J. A. Induced pluripotent stem cell lines derived from human somatic cells. Science 318(5858):1917-1920; 2007.
-
(2007)
Science
, vol.318
, Issue.5858
, pp. 1917-1920
-
-
Yu, J.1
Vodyanik, M.A.2
Smuga-Otto, K.3
Antosiewicz-Bourget, J.4
Frane, J.L.5
Tian, S.6
Nie, J.7
Jonsdottir, G.A.8
Ruotti, V.9
Stewart, R.10
Slukvin, I.I.11
Thomson, J.A.12
-
165
-
-
24944534660
-
Mitochondrial localization of the Parkinson's disease related protein DJ-1
-
Zhang, L.; Shimoji, M.; Thomas, B.; Moore, D. J.; Yu, S. W.; Marupudi, N. I.; Torp, R.; Torgner, I. A.; Ottersen, O. P.; Dawson, T. M.; Dawson, V. L. Mitochondrial localization of the Parkinson's disease related protein DJ-1: Implications for pathogenesis. Hum. Mol. Genet. 14(14):2063-2073; 2005.
-
(2005)
Implications For Pathogenesis. Hum. Mol. Genet
, vol.14
, Issue.14
, pp. 2063-2073
-
-
Zhang, L.1
Shimoji, M.2
Thomas, B.3
Moore, D.J.4
Yu, S.W.5
Marupudi, N.I.6
Torp, R.7
Torgner, I.A.8
Ottersen, O.P.9
Dawson, T.M.10
Dawson, V.L.11
-
166
-
-
8844233579
-
Mutations in LRRK2 cause autosomaldominant parkinsonism with pleomorphic pathology
-
Zimprich, A.; Biskup, S.; Leitner, P.; Lichtner, P.; Farrer, M.; Lincoln, S.; Kachergus, J.; Hulihan, M.; Uitti, R. J.; Calne, D. B.; Stoessl, A. J.; Pfeiffer, R. F.; Patenge, N.; Carbajal, I. C.; Vieregge, P.; Asmus, F.; Muller-Myhsok, B.; Dickson, D. W.; Meitinger, T.; Strom, T. M.; Wszolek, Z. K.; Gasser, T. Mutations in LRRK2 cause autosomaldominant parkinsonism with pleomorphic pathology. Neuron 44(4):601-607; 2004.
-
(2004)
Neuron
, vol.44
, Issue.4
, pp. 601-607
-
-
Zimprich, A.1
Biskup, S.2
Leitner, P.3
Lichtner, P.4
Farrer, M.5
Lincoln, S.6
Kachergus, J.7
Hulihan, M.8
Uitti, R.J.9
Calne, D.B.10
Stoessl, A.J.11
Pfeiffer, R.F.12
Patenge, N.13
Carbajal, I.C.14
Vieregge, P.15
Asmus, F.16
Muller-Myhsok, B.17
Dickson, D.W.18
Meitinger, T.19
Strom, T.M.20
Wszolek, Z.K.21
Gasser, T.22
more..
|