Melatonin as a proteasome inhibitor. is there any clinical evidence?

Life Sciences

Volumn 115, Issue 1, 2014, Pages 8-14

  Vriend, Jerry ^a   Reiter, Russel J ^b  

^a UNIVERSITY OF MANITOBA   (Canada)

^b Mays Cancer Center at UT Health San Antonio   (United States)

Author keywords

Apoptosis; Bax; Bcl 2; Bim; Caspase 3; Caspase 9; kappa beta; Melatonin Proteasome; Nuclear factor; p53; TRAIL; Tumor suppressor

Indexed keywords

APOPTOSOME; BETA CATENIN; BIM PROTEIN; BORTEZOMIB; CASPASE 3; CASPASE 9; CYCLINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MELATONIN; PROTEASOME; PROTEASOME INHIBITOR; PROTEIN BAX; PROTEIN P27; PROTEIN P53; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; VASCULOTROPIN; BORONIC ACID DERIVATIVE; CASPASE; PYRAZINE DERIVATIVE; VASCULOTROPIN A;

APOPTOSIS; CANCER CELL CULTURE; CELL CYCLE REGULATION; DRUG INHIBITION; HEMATOLOGIC MALIGNANCY; HUMAN; HUMAN CELL CULTURE; HYPOTHESIS; NONHUMAN; OXIDATION REDUCTION REACTION; PROTEIN DEPHOSPHORYLATION; REVIEW; SIGNAL TRANSDUCTION; ANIMAL; DRUG EFFECTS; METABOLISM; NEOPLASMS;

ANIMALS; APOPTOSIS; BETA CATENIN; BORONIC ACIDS; CASPASES; HUMANS; MELATONIN; NEOPLASMS; NF-KAPPA B; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEASOME INHIBITORS; PYRAZINES; SIGNAL TRANSDUCTION; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TUMOR SUPPRESSOR PROTEIN P53; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84908042241     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2014.08.024     Document Type: Review

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