-
1
-
-
2342496712
-
FoxOs at the crossroads of cellular metabolism, differentiation, and transformation
-
Accili D, Arden KC. (2004). FoxOs at the crossroads of cellular metabolism, differentiation, and transformation. Cell 117: 421-426.
-
(2004)
Cell
, vol.117
, pp. 421-426
-
-
Accili, D.1
Arden, K.C.2
-
2
-
-
0030590875
-
Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase
-
Alessi DR, Caudwell FB, Andjelkovic M, Hemmings BA, Cohen P. (1996). Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase. FEBS Lett 399: 333-338.
-
(1996)
FEBS Lett
, vol.399
, pp. 333-338
-
-
Alessi, D.R.1
Caudwell, F.B.2
Andjelkovic, M.3
Hemmings, B.A.4
Cohen, P.5
-
3
-
-
0035852715
-
Embryonic expression of the tumor-associated PAX3-FKHR fusion protein interferes with the developmental functions of Pax3
-
Anderson MJ, Shelton GD, Cavenee WK, Arden KC. (2001). Embryonic expression of the tumor-associated PAX3-FKHR fusion protein interferes with the developmental functions of Pax3. Proc Natl Acad Sci USA 98: 1589-1594.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 1589-1594
-
-
Anderson, M.J.1
Shelton, G.D.2
Cavenee, W.K.3
Arden, K.C.4
-
4
-
-
0032518255
-
Cloning and characterization of three human forkhead genes that comprise an FKHR-like gene subfamily
-
Anderson MJ, Viars CS, Czekay S, Cavenee WK, Arden KC. (1998). Cloning and characterization of three human forkhead genes that comprise an FKHR-like gene subfamily. Genomics 47: 187-199.
-
(1998)
Genomics
, vol.47
, pp. 187-199
-
-
Anderson, M.J.1
Viars, C.S.2
Czekay, S.3
Cavenee, W.K.4
Arden, K.C.5
-
5
-
-
0035839886
-
Gene fusions involving PAX and FOX family members in alveolar rhabdomyosarcoma
-
Barr FG. (2001). Gene fusions involving PAX and FOX family members in alveolar rhabdomyosarcoma. Oncogene 20: 5736-5746.
-
(2001)
Oncogene
, vol.20
, pp. 5736-5746
-
-
Barr, F.G.1
-
7
-
-
0035019007
-
Identification and characterization of members of the FKHR (FOX O) subclass of winged-helix transcription factors in the mouse
-
Biggs III WH, Cavenee WK, Arden KC. (2001). Identification and characterization of members of the FKHR (FOX O) subclass of winged-helix transcription factors in the mouse. Mamm Genome 12: 416-425.
-
(2001)
Mamm Genome
, vol.12
, pp. 416-425
-
-
Biggs III, W.H.1
Cavenee, W.K.2
Arden, K.C.3
-
8
-
-
0033595011
-
Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1
-
Biggs III WH, Meisenhelder J, Hunter T, Cavenee WK, Arden KC. (1999). Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1. Proc Natl Acad Sci USA 96: 7421-7426.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 7421-7426
-
-
Biggs III, W.H.1
Meisenhelder, J.2
Hunter, T.3
Cavenee, W.K.4
Arden, K.C.5
-
9
-
-
0037416153
-
FKHR (FOXO1a) is required for myotube fusion of primary mouse myoblasts
-
Bois PR, Grosveld GC. (2003). FKHR (FOXO1a) is required for myotube fusion of primary mouse myoblasts. EMBO J 22: 1147-1157.
-
(2003)
EMBO J
, vol.22
, pp. 1147-1157
-
-
Bois, P.R.1
Grosveld, G.C.2
-
10
-
-
0031031378
-
Cloning and characterization of AFX, the gene that fuses to MLL in acute leukemias with a t(X;11)(q13;q23)
-
Borkhardt A, Repp R, Haas OA, Leis T, Harbott J, Kreuder J et al. (1997). Cloning and characterization of AFX, the gene that fuses to MLL in acute leukemias with a t(X;11)(q13;q23). Oncogene 14: 195-202.
-
(1997)
Oncogene
, vol.14
, pp. 195-202
-
-
Borkhardt, A.1
Repp, R.2
Haas, O.A.3
Leis, T.4
Harbott, J.5
Kreuder, J.6
-
11
-
-
0035034038
-
Inhibition of nuclear import by protein kinase B (Akt) regulates the subcellular distribution and activity of the forkhead transcription factor AFX
-
Brownawell AM, Kops GJ, Macara IG, Burgering BM. (2001). Inhibition of nuclear import by protein kinase B (Akt) regulates the subcellular distribution and activity of the forkhead transcription factor AFX. Mol Cell Biol 21: 3534-3546.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 3534-3546
-
-
Brownawell, A.M.1
Kops, G.J.2
Macara, I.G.3
Burgering, B.M.4
-
12
-
-
0033582929
-
Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
-
Brunet A, Bonni A, Zigmond MJ, Lin MZ, Juo P, Hu LS et al. (1999). Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell 96: 857-868.
-
(1999)
Cell
, vol.96
, pp. 857-868
-
-
Brunet, A.1
Bonni, A.2
Zigmond, M.J.3
Lin, M.Z.4
Juo, P.5
Hu, L.S.6
-
13
-
-
12144290563
-
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
-
Brunet A, Sweeney LB, Sturgill JF, Chua KF, Greer PL, Lin Y et al. (2004). Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science 303: 2011-2015.
-
(2004)
Science
, vol.303
, pp. 2011-2015
-
-
Brunet, A.1
Sweeney, L.B.2
Sturgill, J.F.3
Chua, K.F.4
Greer, P.L.5
Lin, Y.6
-
14
-
-
0036629251
-
Cell cycle and death control: Long live Forkheads
-
Burgering BM, Kops GJ. (2002). Cell cycle and death control: long live Forkheads. Trends Biochem Sci 27: 352-360.
-
(2002)
Trends Biochem Sci
, vol.27
, pp. 352-360
-
-
Burgering, B.M.1
Kops, G.J.2
-
15
-
-
0037205048
-
The phosphoinositide 3-kinase pathway
-
Cantley LC. (2002). The phosphoinositide 3-kinase pathway. Science 296: 1655-1657.
-
(2002)
Science
, vol.296
, pp. 1655-1657
-
-
Cantley, L.C.1
-
16
-
-
0038152845
-
Suppression of ovarian follicle activation in mice by the transcription factor Foxo3a
-
Castrillon DH, Miao L, Kollipara R, Horner JW, DePinho RA. (2003). Suppression of ovarian follicle activation in mice by the transcription factor Foxo3a. Science 301: 215-218.
-
(2003)
Science
, vol.301
, pp. 215-218
-
-
Castrillon, D.H.1
Miao, L.2
Kollipara, R.3
Horner, J.W.4
DePinho, R.A.5
-
17
-
-
0027270989
-
Co-crystal structure of the HNF-3/fork head DNA-recognition motif resembles histone H5
-
Clark KL, Halay ED, Lai E, Burley SK. (1993). Co-crystal structure of the HNF-3/fork head DNA-recognition motif resembles histone H5. Nature 364: 412-420.
-
(1993)
Nature
, vol.364
, pp. 412-420
-
-
Clark, K.L.1
Halay, E.D.2
Lai, E.3
Burley, S.K.4
-
18
-
-
0027184681
-
Acute leukemias of different lineages have similar MLL gene fusions encoding related chimeric proteins resulting from chromosomal translocation
-
Corral J, Forster A, Thompson S, Lampert F, Kaneko Y, Slater R et al. (1993). Acute leukemias of different lineages have similar MLL gene fusions encoding related chimeric proteins resulting from chromosomal translocation. Proc Natl Acad Sci USA 90: 8538-8542.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 8538-8542
-
-
Corral, J.1
Forster, A.2
Thompson, S.3
Lampert, F.4
Kaneko, Y.5
Slater, R.6
-
19
-
-
0032752063
-
Cellular survival: A play in three Akts
-
Datta SR, Brunet A, Greenberg ME. (1999). Cellular survival: a play in three Akts. Genes Dev 13: 2905-2927.
-
(1999)
Genes Dev
, vol.13
, pp. 2905-2927
-
-
Datta, S.R.1
Brunet, A.2
Greenberg, M.E.3
-
20
-
-
0033518120
-
Regulation of the forkhead transcription factor FKHR, but not the PAX3-FKHR fusion protein, by the serine/threonine kinase Akt
-
del Peso L, Gonzalez VM, Hernandez R, Barr FG, Nunez G. (1999). Regulation of the forkhead transcription factor FKHR, but not the PAX3-FKHR fusion protein, by the serine/threonine kinase Akt. Oncogene 18: 7328-7333.
-
(1999)
Oncogene
, vol.18
, pp. 7328-7333
-
-
del Peso, L.1
Gonzalez, V.M.2
Hernandez, R.3
Barr, F.G.4
Nunez, G.5
-
21
-
-
0034609737
-
Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1
-
Dijkers PF, Medema RH, Lammers JW, Koenderman L, Coffer PJ. (2000). Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1. Curr Biol 10: 1201-1204.
-
(2000)
Curr Biol
, vol.10
, pp. 1201-1204
-
-
Dijkers, P.F.1
Medema, R.H.2
Lammers, J.W.3
Koenderman, L.4
Coffer, P.J.5
-
22
-
-
0242580872
-
Convergence of peroxisome proliferator-activated receptor gamma and Foxo1 signaling pathways
-
Dowell P, Otto TC, Adi S, Lane MD. (2003). Convergence of peroxisome proliferator-activated receptor gamma and Foxo1 signaling pathways. J Biol Chem 278: 45485-45491.
-
(2003)
J Biol Chem
, vol.278
, pp. 45485-45491
-
-
Dowell, P.1
Otto, T.C.2
Adi, S.3
Lane, M.D.4
-
23
-
-
18844382368
-
Functional interaction between beta-catenin and FOXO in oxidative stress signaling
-
Essers MA, de Vries-Smits LM, Barker N, Polderman PE, Burgering BM, Korswagen HC. (2005). Functional interaction between beta-catenin and FOXO in oxidative stress signaling. Science 308: 1181-1184.
-
(2005)
Science
, vol.308
, pp. 1181-1184
-
-
Essers, M.A.1
de Vries-Smits, L.M.2
Barker, N.3
Polderman, P.E.4
Burgering, B.M.5
Korswagen, H.C.6
-
24
-
-
2342445654
-
Negative regulation of forkhead transcription factor AFX (Foxo4) by CBP-induced acetylation
-
Fukuoka M, Daitoku H, Hatta M, Matsuzaki H, Umemura S, Fukamizu A. (2003). Negative regulation of forkhead transcription factor AFX (Foxo4) by CBP-induced acetylation. Int J Mol Med 12: 503-508.
-
(2003)
Int J Mol Med
, vol.12
, pp. 503-508
-
-
Fukuoka, M.1
Daitoku, H.2
Hatta, M.3
Matsuzaki, H.4
Umemura, S.5
Fukamizu, A.6
-
25
-
-
4544227785
-
Abnormal angiogenesis in Foxo1 (Fkhr)-deficient mice
-
Furuyama T, Kitayama K, Shimoda Y, Ogawa M, Sone K, Yoshida-Araki K et al. (2004). Abnormal angiogenesis in Foxo1 (Fkhr)-deficient mice. J Biol Chem 279: 34741-34749.
-
(2004)
J Biol Chem
, vol.279
, pp. 34741-34749
-
-
Furuyama, T.1
Kitayama, K.2
Shimoda, Y.3
Ogawa, M.4
Sone, K.5
Yoshida-Araki, K.6
-
26
-
-
0034661826
-
Identification of the differential distribution patterns of mRNAs and consensus binding sequences formouse DAF-16 homologues
-
Furuyama T, Nakazawa T, Nakano I, Mori N. (2000). Identification of the differential distribution patterns of mRNAs and consensus binding sequences formouse DAF-16 homologues. Biochem J 349: 629-634.
-
(2000)
Biochem J
, vol.349
, pp. 629-634
-
-
Furuyama, T.1
Nakazawa, T.2
Nakano, I.3
Mori, N.4
-
27
-
-
0027521658
-
Fusion of a fork head domain gene to PAX3 in the solid tumour alveolar rhabdomyosarcoma
-
Galili N, Davis RJ, Fredericks WJ, Mukhopadhyay S, Rauscher III FJ, Emanuel BS et al. (1993). Fusion of a fork head domain gene to PAX3 in the solid tumour alveolar rhabdomyosarcoma. Nat Genet 5: 230-235.
-
(1993)
Nat Genet
, vol.5
, pp. 230-235
-
-
Galili, N.1
Davis, R.J.2
Fredericks, W.J.3
Mukhopadhyay, S.4
Rauscher III, F.J.5
Emanuel, B.S.6
-
28
-
-
0042477712
-
FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons
-
Gilley J, Coffer PJ, Ham J. (2003). FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons. J Cell Biol 162: 613-622.
-
(2003)
J Cell Biol
, vol.162
, pp. 613-622
-
-
Gilley, J.1
Coffer, P.J.2
Ham, J.3
-
29
-
-
27844497945
-
FOXO transcription factors at the interface between longevity and tumor suppression
-
Greer EL, Brunet A. (2005). FOXO transcription factors at the interface between longevity and tumor suppression. Oncogene 24: 7410-7425.
-
(2005)
Oncogene
, vol.24
, pp. 7410-7425
-
-
Greer, E.L.1
Brunet, A.2
-
30
-
-
0030869789
-
AF6q21, a novel partner of the MLL gene in t(6;11)(q21;q23), defines a forkhead transcriptional factor subfamily
-
Hillion J, Le Coniat M, Jonveaux P, Berger R, Bernard OA. (1997). AF6q21, a novel partner of the MLL gene in t(6;11)(q21;q23), defines a forkhead transcriptional factor subfamily. Blood 90: 3714-3719.
-
(1997)
Blood
, vol.90
, pp. 3714-3719
-
-
Hillion, J.1
Le Coniat, M.2
Jonveaux, P.3
Berger, R.4
Bernard, O.A.5
-
31
-
-
1542267804
-
-
Hosaka T, Biggs III WH, Tieu D, BoyerAD, Varki NM, Cavenee WK et al. (2004). Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification. Proc Natl Acad Sci USA 101: 2975-2980.
-
Hosaka T, Biggs III WH, Tieu D, BoyerAD, Varki NM, Cavenee WK et al. (2004). Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification. Proc Natl Acad Sci USA 101: 2975-2980.
-
-
-
-
32
-
-
11144357466
-
IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a
-
Hu MC, Lee DF, Xia W, Golfman LS, Ou-Yang F, Yang JY et al. (2004). IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a. Cell 117: 225-237.
-
(2004)
Cell
, vol.117
, pp. 225-237
-
-
Hu, M.C.1
Lee, D.F.2
Xia, W.3
Golfman, L.S.4
Ou-Yang, F.5
Yang, J.Y.6
-
33
-
-
33750032892
-
CDK2-dependent phosphorylation of FOXO1 as an apoptotic response to DNA damage
-
Huang H, Regan KM, Lou Z, Chen J, Tindall DJ. (2006). CDK2-dependent phosphorylation of FOXO1 as an apoptotic response to DNA damage. Science 314: 294-297.
-
(2006)
Science
, vol.314
, pp. 294-297
-
-
Huang, H.1
Regan, K.M.2
Lou, Z.3
Chen, J.4
Tindall, D.J.5
-
34
-
-
13444252337
-
Skp2 inhibits FOXO1 in tumor suppression through ubiquitin-mediated degradation
-
Huang H, Regan KM, Wang F, Wang D, Smith DI, van Deursen JM et al. (2005). Skp2 inhibits FOXO1 in tumor suppression through ubiquitin-mediated degradation. Proc Natl Acad Sci USA 102: 1649-1654.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 1649-1654
-
-
Huang, H.1
Regan, K.M.2
Wang, F.3
Wang, D.4
Smith, D.I.5
van Deursen, J.M.6
-
35
-
-
0141481091
-
FoxO6, a novel member of the FoxO class of transcription factors with distinct shuttling dynamics
-
Jacobs FM, van der Heide LP, Wijchers PJ, Burbach JP, Hoekman MF, Smidt MP. (2003). FoxO6, a novel member of the FoxO class of transcription factors with distinct shuttling dynamics. J Biol Chem 278: 35959-35967.
-
(2003)
J Biol Chem
, vol.278
, pp. 35959-35967
-
-
Jacobs, F.M.1
van der Heide, L.P.2
Wijchers, P.J.3
Burbach, J.P.4
Hoekman, M.F.5
Smidt, M.P.6
-
36
-
-
0342614209
-
Unified nomenclature for the winged helix/forkhead transcription factors
-
Kaestner KH, Knochel W, Martinez DE. (2000). Unified nomenclature for the winged helix/forkhead transcription factors. Genes Dev 14: 142-146.
-
(2000)
Genes Dev
, vol.14
, pp. 142-146
-
-
Kaestner, K.H.1
Knochel, W.2
Martinez, D.E.3
-
37
-
-
0347747970
-
A chemical genetic screen identifies inhibitors of regulated nuclear export of a Forkhead transcription factor in PTEN-deficient tumor cells
-
Kau TR, Schroeder F, Ramaswamy S, Wojciechowski CL, Zhao JJ, Roberts TM et al. (2003). A chemical genetic screen identifies inhibitors of regulated nuclear export of a Forkhead transcription factor in PTEN-deficient tumor cells. Cancer Cell 4: 463-476.
-
(2003)
Cancer Cell
, vol.4
, pp. 463-476
-
-
Kau, T.R.1
Schroeder, F.2
Ramaswamy, S.3
Wojciechowski, C.L.4
Zhao, J.J.5
Roberts, T.M.6
-
38
-
-
17344379513
-
Five years on the wings of fork head
-
Kaufmann E, Knochel W. (1996). Five years on the wings of fork head. Mech Dev 57: 3-20.
-
(1996)
Mech Dev
, vol.57
, pp. 3-20
-
-
Kaufmann, E.1
Knochel, W.2
-
39
-
-
7544243041
-
Alveolar rhabdomyosarcomas in conditional Pax3:Fkhr mice: Cooperativity of Ink4a/ARF and Trp53 loss of function
-
Keller C, Arenkiel BR, Coffin CM, El-Bardeesy N, DePinho RA, Capecchi MR. (2004a). Alveolar rhabdomyosarcomas in conditional Pax3:Fkhr mice: cooperativity of Ink4a/ARF and Trp53 loss of function. Genes Dev 18: 2614-2626.
-
(2004)
Genes Dev
, vol.18
, pp. 2614-2626
-
-
Keller, C.1
Arenkiel, B.R.2
Coffin, C.M.3
El-Bardeesy, N.4
DePinho, R.A.5
Capecchi, M.R.6
-
40
-
-
7544235883
-
Pax3:Fkhr interferes with embryonic Pax3 and Pax7 function: Implications for alveolar rhabdomyosarcoma cell of origin
-
Keller C, Hansen MS, Coffin CM, Capecchi MR. (2004b). Pax3:Fkhr interferes with embryonic Pax3 and Pax7 function: implications for alveolar rhabdomyosarcoma cell of origin. Genes Dev 18: 2608-2613.
-
(2004)
Genes Dev
, vol.18
, pp. 2608-2613
-
-
Keller, C.1
Hansen, M.S.2
Coffin, C.M.3
Capecchi, M.R.4
-
41
-
-
0033451965
-
A genetic analysis of PAX3-FKHR, the oncogene of alveolar rhabdomyosarcoma
-
Kempf BE, Vogt PK. (1999). A genetic analysis of PAX3-FKHR, the oncogene of alveolar rhabdomyosarcoma. Cell Growth Differ 10: 813-818.
-
(1999)
Cell Growth Differ
, vol.10
, pp. 813-818
-
-
Kempf, B.E.1
Vogt, P.K.2
-
42
-
-
0033560896
-
Direct control of the Forkhead transcription factor AFX by protein kinase B
-
Kops GJ, de Ruiter ND, De Vries-Smits AM, Powell DR, Bos JL, Burgering BM. (1999). Direct control of the Forkhead transcription factor AFX by protein kinase B. Nature 398: 630-634.
-
(1999)
Nature
, vol.398
, pp. 630-634
-
-
Kops, G.J.1
de Ruiter, N.D.2
De Vries-Smits, A.M.3
Powell, D.R.4
Bos, J.L.5
Burgering, B.M.6
-
43
-
-
0036787919
-
Pax3-FKHR knock-in mice show developmental aberrations but do not develop tumors
-
Lagutina I, Conway SJ, Sublett J, Grosveld GC. (2002). Pax3-FKHR knock-in mice show developmental aberrations but do not develop tumors. Mol Cell Biol 22: 7204-7216.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 7204-7216
-
-
Lagutina, I.1
Conway, S.J.2
Sublett, J.3
Grosveld, G.C.4
-
44
-
-
0037216526
-
AKT-independent protection of prostate cancer cells from apoptosis mediated through complex formation between the androgen receptor and FKHR
-
Li P, Lee H, Guo S, Unterman TG, Jenster G, Bai W. (2003). AKT-independent protection of prostate cancer cells from apoptosis mediated through complex formation between the androgen receptor and FKHR. Mol Cell Biol 23: 104-118.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 104-118
-
-
Li, P.1
Lee, H.2
Guo, S.3
Unterman, T.G.4
Jenster, G.5
Bai, W.6
-
45
-
-
0030657540
-
Daf-16: An HNF-3/ forkhead family member that can function to double the life-span of Caenorhabditis elegans
-
Lin K, Dorman JB, Rodan A, Kenyon C. (1997). Daf-16: an HNF-3/ forkhead family member that can function to double the life-span of Caenorhabditis elegans. Science 278: 1319-1322.
-
(1997)
Science
, vol.278
, pp. 1319-1322
-
-
Lin, K.1
Dorman, J.B.2
Rodan, A.3
Kenyon, C.4
-
46
-
-
0141706357
-
Insulin-induced phosphorylation of FKHR (Foxo1) targets to proteasomal degradation
-
Matsuzaki H, Daitoku H, Hatta M, Tanaka K, Fukamizu A. (2003). Insulin-induced phosphorylation of FKHR (Foxo1) targets to proteasomal degradation. Proc Natl Acad Sci USA 100: 11285-11290.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 11285-11290
-
-
Matsuzaki, H.1
Daitoku, H.2
Hatta, M.3
Tanaka, K.4
Fukamizu, A.5
-
47
-
-
0034643331
-
AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1
-
Medema RH, Kops GJ, Bos JL, Burgering BM. (2000). AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1. Nature 404: 782-787.
-
(2000)
Nature
, vol.404
, pp. 782-787
-
-
Medema, R.H.1
Kops, G.J.2
Bos, J.L.3
Burgering, B.M.4
-
48
-
-
0037033005
-
FOXO proteins regulate tumor necrosis factor-related apoptosis inducing ligand expression. Implications for PTEN mutation in prostate cancer
-
Modur V, Nagarajan R, Evers BM, Milbrandt J. (2002). FOXO proteins regulate tumor necrosis factor-related apoptosis inducing ligand expression. Implications for PTEN mutation in prostate cancer. J Biol Chem 277: 47928-47937.
-
(2002)
J Biol Chem
, vol.277
, pp. 47928-47937
-
-
Modur, V.1
Nagarajan, R.2
Evers, B.M.3
Milbrandt, J.4
-
49
-
-
1342264308
-
Mammalian SIRT1 represses forkhead transcription factors
-
Motta MC, Divecha N, Lemieux M, Kamel C, Chen D, Gu W et al. (2004). Mammalian SIRT1 represses forkhead transcription factors. Cell 116: 551-563.
-
(2004)
Cell
, vol.116
, pp. 551-563
-
-
Motta, M.C.1
Divecha, N.2
Lemieux, M.3
Kamel, C.4
Chen, D.5
Gu, W.6
-
50
-
-
0033522897
-
Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a Wortmannin-sensitive pathway
-
Nakae J, Park BC, Accili D. (1999). Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a Wortmannin-sensitive pathway. J Biol Chem 274: 15982-15985.
-
(1999)
J Biol Chem
, vol.274
, pp. 15982-15985
-
-
Nakae, J.1
Park, B.C.2
Accili, D.3
-
51
-
-
0034462121
-
Forkhead transcription factors are critical effectors of cell death and cell cycle arrest downstream of PTEN
-
Nakamura N, Ramaswamy S, Vazquez F, Signoretti S, Loda M, Sellers WR. (2000). Forkhead transcription factors are critical effectors of cell death and cell cycle arrest downstream of PTEN. Mol Cell Biol 20: 8969-8982.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 8969-8982
-
-
Nakamura, N.1
Ramaswamy, S.2
Vazquez, F.3
Signoretti, S.4
Loda, M.5
Sellers, W.R.6
-
52
-
-
33846295218
-
FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis
-
Paik JH, Kollipara R, Chu G, Ji H, Xiao Y, Ding Z et al. (2007). FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis. Cell 128: 309-323.
-
(2007)
Cell
, vol.128
, pp. 309-323
-
-
Paik, J.H.1
Kollipara, R.2
Chu, G.3
Ji, H.4
Xiao, Y.5
Ding, Z.6
-
53
-
-
0027959091
-
Cloning and characterization of the t(X;11) breakpoint from a leukemic cell line identify a new member of the forkhead gene family
-
Parry P, Wei Y, Evans G. (1994). Cloning and characterization of the t(X;11) breakpoint from a leukemic cell line identify a new member of the forkhead gene family. Genes Chromosomes Cancer 11: 79-84.
-
(1994)
Genes Chromosomes Cancer
, vol.11
, pp. 79-84
-
-
Parry, P.1
Wei, Y.2
Evans, G.3
-
54
-
-
0038506780
-
Characterization of insulin inhibition of transactivation by a C-terminal fragment of the forkhead transcription factor Foxo1 in rat hepatoma cells
-
Perrot V, Rechler MM. (2003). Characterization of insulin inhibition of transactivation by a C-terminal fragment of the forkhead transcription factor Foxo1 in rat hepatoma cells. J Biol Chem 278: 26111-26119.
-
(2003)
J Biol Chem
, vol.278
, pp. 26111-26119
-
-
Perrot, V.1
Rechler, M.M.2
-
55
-
-
0038187621
-
Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction
-
Puigserver P, Rhee J, Donovan J, Walkey CJ, Yoon JC, Oriente F et al. (2003). Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction. Nature 423: 550-555.
-
(2003)
Nature
, vol.423
, pp. 550-555
-
-
Puigserver, P.1
Rhee, J.2
Donovan, J.3
Walkey, C.J.4
Yoon, J.C.5
Oriente, F.6
-
56
-
-
0036651790
-
A novel mechanism of gene regulation and tumor suppression by the transcription factor FKHR
-
Ramaswamy S, Nakamura N, Sansal I, Bergeron L, Sellers WR. (2002). A novel mechanism of gene regulation and tumor suppression by the transcription factor FKHR. Cancer Cell 2: 81-91.
-
(2002)
Cancer Cell
, vol.2
, pp. 81-91
-
-
Ramaswamy, S.1
Nakamura, N.2
Sansal, I.3
Bergeron, L.4
Sellers, W.R.5
-
57
-
-
0347384010
-
The transcriptional activator PAX3-FKHR rescues the defects of Pax3 mutant mice but induces a myogenic gain-of-function phenotype with ligand-independent activation of Met signaling in vivo
-
Relaix F, Polimeni M, Rocancourt D, Ponzetto C, Schafer BW, Buckingham M. (2003). The transcriptional activator PAX3-FKHR rescues the defects of Pax3 mutant mice but induces a myogenic gain-of-function phenotype with ligand-independent activation of Met signaling in vivo. Genes Dev 17: 2950-2965.
-
(2003)
Genes Dev
, vol.17
, pp. 2950-2965
-
-
Relaix, F.1
Polimeni, M.2
Rocancourt, D.3
Ponzetto, C.4
Schafer, B.W.5
Buckingham, M.6
-
58
-
-
0033546439
-
Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B
-
Rena G, Guo S, Cichy SC, Unterman TG, Cohen P. (1999). Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B. J Biol Chem 274: 17179-17183.
-
(1999)
J Biol Chem
, vol.274
, pp. 17179-17183
-
-
Rena, G.1
Guo, S.2
Cichy, S.C.3
Unterman, T.G.4
Cohen, P.5
-
59
-
-
0036191716
-
Expression of FKHR, FKHRL1, and AFX genes in the rodent ovary: Evidence for regulation by IGF-I, estrogen, and the gonadotropins
-
Richards JS, Sharma SC, Falender AE, Lo YH. (2002). Expression of FKHR, FKHRL1, and AFX genes in the rodent ovary: evidence for regulation by IGF-I, estrogen, and the gonadotropins. Mol Endocrinol 16: 580-599.
-
(2002)
Mol Endocrinol
, vol.16
, pp. 580-599
-
-
Richards, J.S.1
Sharma, S.C.2
Falender, A.E.3
Lo, Y.H.4
-
60
-
-
0029796402
-
The hybrid PAX3-FKHR fusion protein of alveolar rhabdomyosarcoma transforms fibroblasts in culture
-
Scheidler S, Fredericks WJ, Rauscher III FJ, Barr FG, Vogt PK. (1996). The hybrid PAX3-FKHR fusion protein of alveolar rhabdomyosarcoma transforms fibroblasts in culture. Proc Natl Acad Sci USA 93: 9805-9809.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 9805-9809
-
-
Scheidler, S.1
Fredericks, W.J.2
Rauscher III, F.J.3
Barr, F.G.4
Vogt, P.K.5
-
61
-
-
17844365847
-
The psammaplysenes, specific inhibitors of FOXO1a nuclear export
-
Schroeder FC, Kau TR, Silver PA, Clardy J. (2005). The psammaplysenes, specific inhibitors of FOXO1a nuclear export. J Nat Prod 68: 574-576.
-
(2005)
J Nat Prod
, vol.68
, pp. 574-576
-
-
Schroeder, F.C.1
Kau, T.R.2
Silver, P.A.3
Clardy, J.4
-
62
-
-
1642332084
-
Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation
-
Seoane J, Le HV, Shen L, Anderson SA, Massague J. (2004). Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation. Cell 117: 211-223.
-
(2004)
Cell
, vol.117
, pp. 211-223
-
-
Seoane, J.1
Le, H.V.2
Shen, L.3
Anderson, S.A.4
Massague, J.5
-
63
-
-
0037094096
-
The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2
-
Stahl M, Dijkers PF, Kops GJ, Lens SM, Coffer PJ, Burgering BM et al. (2002). The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2. J Immunol 168: 5024-5031.
-
(2002)
J Immunol
, vol.168
, pp. 5024-5031
-
-
Stahl, M.1
Dijkers, P.F.2
Kops, G.J.3
Lens, S.M.4
Coffer, P.J.5
Burgering, B.M.6
-
64
-
-
10744230034
-
FoxO3a transcriptional regulation of Bim controls apoptosis in paclitaxel-treated breast cancer cell lines
-
Sunters A, Fernandez de Mattos S, Stahl M, Brosens JJ, Zoumpoulidou G, Saunders CA et al. (2003). FoxO3a transcriptional regulation of Bim controls apoptosis in paclitaxel-treated breast cancer cell lines. J Biol Chem 278: 49795-49805.
-
(2003)
J Biol Chem
, vol.278
, pp. 49795-49805
-
-
Sunters, A.1
Fernandez de Mattos, S.2
Stahl, M.3
Brosens, J.J.4
Zoumpoulidou, G.5
Saunders, C.A.6
-
65
-
-
13044315956
-
Regulation of nuclear translocation of forkhead transcription factor AFX by protein kinase B
-
Takaishi H, Konishi H, Matsuzaki H, Ono Y, Shirai Y, Saito N et al. (1999). Regulation of nuclear translocation of forkhead transcription factor AFX by protein kinase B. Proc Natl Acad Sci USA 96: 11836-11841.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 11836-11841
-
-
Takaishi, H.1
Konishi, H.2
Matsuzaki, H.3
Ono, Y.4
Shirai, Y.5
Saito, N.6
-
66
-
-
0039425278
-
Negative regulation of the forkhead transcription factor FKHR by Akt
-
Tang ED, Nunez G, Barr FG, Guan KL. (1999). Negative regulation of the forkhead transcription factor FKHR by Akt. J Biol Chem 274: 16741-16746.
-
(1999)
J Biol Chem
, vol.274
, pp. 16741-16746
-
-
Tang, E.D.1
Nunez, G.2
Barr, F.G.3
Guan, K.L.4
-
67
-
-
0037134491
-
The forkhead transcription factor AFX activates apoptosis by induction of the BCL-6 transcriptional repressor
-
Tang TT, Dowbenko D, Jackson A, Toney L, Lewin DA, Dent AL et al. (2002). The forkhead transcription factor AFX activates apoptosis by induction of the BCL-6 transcriptional repressor. J Biol Chem 277: 14255-14265.
-
(2002)
J Biol Chem
, vol.277
, pp. 14255-14265
-
-
Tang, T.T.1
Dowbenko, D.2
Jackson, A.3
Toney, L.4
Lewin, D.A.5
Dent, A.L.6
-
68
-
-
33846419112
-
FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress
-
Tothova Z, Kollipara R, Huntly BJ, Lee BH, Castrillon DH, Cullen DE et al. (2007). FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress. Cell 128: 325-339.
-
(2007)
Cell
, vol.128
, pp. 325-339
-
-
Tothova, Z.1
Kollipara, R.2
Huntly, B.J.3
Lee, B.H.4
Castrillon, D.H.5
Cullen, D.E.6
-
69
-
-
0037134040
-
-
Tran H, Brunet A, Grenier JM, Datta SR, Fornace Jr AJ, DiStefano PS et al. (2002). DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein. Science 296: 530-534.
-
Tran H, Brunet A, Grenier JM, Datta SR, Fornace Jr AJ, DiStefano PS et al. (2002). DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein. Science 296: 530-534.
-
-
-
-
70
-
-
3142742707
-
FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2 (SIRT1)
-
van der Horst A, Tertoolen LG, de Vries-Smits LM, Frye RA, Medema RH, Burgering BM. (2004). FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2 (SIRT1). J Biol Chem 279: 28873-28879.
-
(2004)
J Biol Chem
, vol.279
, pp. 28873-28879
-
-
van der Horst, A.1
Tertoolen, L.G.2
de Vries-Smits, L.M.3
Frye, R.A.4
Medema, R.H.5
Burgering, B.M.6
-
71
-
-
0036632368
-
The phosphatidylinositol 3-Kinase AKT pathway in human cancer
-
Vivanco I, Sawyers CL. (2002). The phosphatidylinositol 3-Kinase AKT pathway in human cancer. Nat Rev Cancer 2: 489-501.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 489-501
-
-
Vivanco, I.1
Sawyers, C.L.2
-
72
-
-
25444442080
-
Triple layer control: Phosphorylation, acetylation and ubiquitination of FOXO proteins
-
Vogt PK, Jiang H, Aoki M. (2005). Triple layer control: phosphorylation, acetylation and ubiquitination of FOXO proteins. Cell Cycle 4: 908-913.
-
(2005)
Cell Cycle
, vol.4
, pp. 908-913
-
-
Vogt, P.K.1
Jiang, H.2
Aoki, M.3
-
73
-
-
4644310947
-
Analysis of the transforming and growth suppressive activities of the PAX3-FKHR oncoprotein
-
Xia SJ, Barr FG. (2004). Analysis of the transforming and growth suppressive activities of the PAX3-FKHR oncoprotein. Oncogene 23: 6864-6871.
-
(2004)
Oncogene
, vol.23
, pp. 6864-6871
-
-
Xia, S.J.1
Barr, F.G.2
-
75
-
-
29644442757
-
Genome-wide promoter extraction and analysis in human, mouse, and rat
-
Xuan Z, Zhao F, Wang J, Chen G, Zhang MQ. (2005). Genome-wide promoter extraction and analysis in human, mouse, and rat. Genome Biol 6: R72.
-
(2005)
Genome Biol
, vol.6
-
-
Xuan, Z.1
Zhao, F.2
Wang, J.3
Chen, G.4
Zhang, M.Q.5
-
76
-
-
33646189483
-
RUNX3 cooperates with FoxO3a to induce apoptosis in gastric cancer cells
-
Yamamura Y, Lee WL, Inoue K, Ida H, Ito Y. (2006). RUNX3 cooperates with FoxO3a to induce apoptosis in gastric cancer cells. J Biol Chem 281: 5267-5276.
-
(2006)
J Biol Chem
, vol.281
, pp. 5267-5276
-
-
Yamamura, Y.1
Lee, W.L.2
Inoue, K.3
Ida, H.4
Ito, Y.5
-
77
-
-
16244415180
-
Constitutively active FOXO4 inhibits Akt activity, regulates p27 Kip1 stability, and suppresses HER2-mediated tumorigenicity
-
Yang H, Zhao R, Yang HY, Lee MH. (2005). Constitutively active FOXO4 inhibits Akt activity, regulates p27 Kip1 stability, and suppresses HER2-mediated tumorigenicity. Oncogene 24: 1924-1935.
-
(2005)
Oncogene
, vol.24
, pp. 1924-1935
-
-
Yang, H.1
Zhao, R.2
Yang, H.Y.3
Lee, M.H.4
-
78
-
-
0037414791
-
PAX3-FKHR transformation increases 26 S proteasome-dependent degradation of p27Kip1, a potential role for elevated Skp2 expression
-
Zhang L, Wang C. (2003). PAX3-FKHR transformation increases 26 S proteasome-dependent degradation of p27Kip1, a potential role for elevated Skp2 expression. J Biol Chem 278: 27-36.
-
(2003)
J Biol Chem
, vol.278
, pp. 27-36
-
-
Zhang, L.1
Wang, C.2
|