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Volumn 98, Issue 3, 2001, Pages 795-804

TRAIL/Apo2L ligand selectively induces apoptosis and overcomes drug resistance in multiple myeloma: Therapeutic applications

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS INDUCING FACTOR; BORTEZOMIB; DEXAMETHASONE; DOXORUBICIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; LIGAND; MELPHALAN; MITOXANTRONE; PROTEASOME INHIBITOR; RECEPTOR PROTEIN; RECOMBINANT PROTEIN; TRAIL RECEPTOR DEATH RECEPTOR 5; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG;

EID: 0035437171     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.V98.3.795     Document Type: Article
Times cited : (350)

References (59)
  • 1
    • 8944220233 scopus 로고    scopus 로고
    • A prospective, randomized trial of autologous bone marrow transplantation and chemotherapy in multiple myeloma
    • Attal M, Harousseau JL, Stoppa AM, et al. A prospective, randomized trial of autologous bone marrow transplantation and chemotherapy in multiple myeloma. N Engl J Med. 1996;335:91-97.
    • (1996) N Engl J Med , vol.335 , pp. 91-97
    • Attal, M.1    Harousseau, J.L.2    Stoppa, A.M.3
  • 3
    • 0033060871 scopus 로고    scopus 로고
    • Bone marrow transplantation in multiple myeloma
    • Schlossman RL, Anderson KC. Bone marrow transplantation in multiple myeloma. Curr Opin Oncol. 1999;11:102-108.
    • (1999) Curr Opin Oncol , vol.11 , pp. 102-108
    • Schlossman, R.L.1    Anderson, K.C.2
  • 4
    • 0032929520 scopus 로고    scopus 로고
    • Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo
    • Walczak H, Miller RE, Ariail K, et al. Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo. Nat Med, 1999;5:157-163.
    • (1999) Nat Med , vol.5 , pp. 157-163
    • Walczak, H.1    Miller, R.E.2    Ariail, K.3
  • 6
    • 0032530612 scopus 로고    scopus 로고
    • Intracellular regulation of TRAIL-induced apoptosis in human melanoma cells
    • Griffith TS, Chin WA, Jackson GC, Lynch DH, Kubin MZ. Intracellular regulation of TRAIL-induced apoptosis in human melanoma cells. J Immunol. 1998;161:2833-2840.
    • (1998) J Immunol , vol.161 , pp. 2833-2840
    • Griffith, T.S.1    Chin, W.A.2    Jackson, G.C.3    Lynch, D.H.4    Kubin, M.Z.5
  • 7
    • 0032713075 scopus 로고    scopus 로고
    • Safety and antitumor activity of recombinant soluble Apo2 ligand
    • Ashkenazi A, Pai RC, Fong S, et al. Safety and antitumor activity of recombinant soluble Apo2 ligand. J Clin Invest. 1999;104:155-162.
    • (1999) J Clin Invest , vol.104 , pp. 155-162
    • Ashkenazi, A.1    Pai, R.C.2    Fong, S.3
  • 8
    • 17544367410 scopus 로고    scopus 로고
    • Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family
    • Pitti RM, Marsters SA, Ruppert S, Donahue CJ, Moore A, Ashkenazi A. Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family. J Biol Chem. 1996;271:12687-12690.
    • (1996) J Biol Chem , vol.271 , pp. 12687-12690
    • Pitti, R.M.1    Marsters, S.A.2    Ruppert, S.3    Donahue, C.J.4    Moore, A.5    Ashkenazi, A.6
  • 9
  • 10
    • 13344285339 scopus 로고
    • Identification and characterization of a new member of the TNF family that induces apoptosis
    • Wiley SR, Schooley K, Smolak PJ, et al. Identification and characterization of a new member of the TNF family that induces apoptosis. Immunity. 1995;3:673-682.
    • (1995) Immunity , vol.3 , pp. 673-682
    • Wiley, S.R.1    Schooley, K.2    Smolak, P.J.3
  • 11
    • 0032169208 scopus 로고    scopus 로고
    • TNF-related apoptosis-inducing ligand (TRAIL) induces apoptosis in Fas ligand-resistant melanoma cells and mediates CD4 T cell killing of target cells
    • Thomas WD, Hersey P. TNF-related apoptosis-inducing ligand (TRAIL) induces apoptosis in Fas ligand-resistant melanoma cells and mediates CD4 T cell killing of target cells. J Immunol. 1998;161:2195-2200.
    • (1998) J Immunol , vol.161 , pp. 2195-2200
    • Thomas, W.D.1    Hersey, P.2
  • 12
    • 0033136301 scopus 로고    scopus 로고
    • Sensitization of AIDS-Kaposi's sarcoma cells to Apo-2 ligand-induced apoptosis by actinomycin D
    • Mori S, Murakami-Mori K, Nakamura S, Ashkenazi A, Bonavida B. Sensitization of AIDS-Kaposi's sarcoma cells to Apo-2 ligand-induced apoptosis by actinomycin D. J Immunol. 1999;162:5616-5623.
    • (1999) J Immunol , vol.162 , pp. 5616-5623
    • Mori, S.1    Murakami-Mori, K.2    Nakamura, S.3    Ashkenazi, A.4    Bonavida, B.5
  • 13
    • 0034194137 scopus 로고    scopus 로고
    • Tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in androgen-independent prostate cancer cells
    • Yu R, Mandlekar S, Ruben S, Ni J, Kong AN. Tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in androgen-independent prostate cancer cells. Cancer Res. 2000;60:2384-2389.
    • (2000) Cancer Res , vol.60 , pp. 2384-2389
    • Yu, R.1    Mandlekar, S.2    Ruben, S.3    Ni, J.4    Kong, A.N.5
  • 14
    • 0033883775 scopus 로고    scopus 로고
    • Thyroid carcinoma cells are resistant to FAS-mediated apoptosis but sensitive to tumor necrosis factor-related apoptosis-inducing ligand
    • Mitsiades N, Poulaki V, Tseleni-Balafouta S, Koutras DA, Stamenkovic I. Thyroid carcinoma cells are resistant to FAS-mediated apoptosis but sensitive to tumor necrosis factor-related apoptosis-inducing ligand. Cancer Res. 2000;60:4122-4129.
    • (2000) Cancer Res , vol.60 , pp. 4122-4129
    • Mitsiades, N.1    Poulaki, V.2    Tseleni-Balafouta, S.3    Koutras, D.A.4    Stamenkovic, I.5
  • 15
    • 0035866804 scopus 로고    scopus 로고
    • Ewing's sarcoma family tumors are sensitive to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and express DR4 and DR5 receptors
    • Mitsiades N, Poulaki V, Mitsiades C, Tsokos M. Ewing's sarcoma family tumors are sensitive to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and express DR4 and DR5 receptors. Cancer Res. 2001;618:2704-2712.
    • (2001) Cancer Res , vol.618 , pp. 2704-2712
    • Mitsiades, N.1    Poulaki, V.2    Mitsiades, C.3    Tsokos, M.4
  • 16
    • 0031782909 scopus 로고    scopus 로고
    • TRAIL a molecule with multiple receptors and control mechanisms
    • Griffith TS, Lynch DH. TRAIL: a molecule with multiple receptors and control mechanisms. Curr Opin Immunol. 1998;10:559-563.
    • (1998) Curr Opin Immunol , vol.10 , pp. 559-563
    • Griffith, T.S.1    Lynch, D.H.2
  • 17
    • 0001560011 scopus 로고    scopus 로고
    • Recombinant human TNF-related apoptosis inducing ligand (hu TRAIL) induces apoptosis of human multiple myeloma (MM) cells
    • Treon SP, Chauhan D, Raje N, Teoh G, Webb I, Anderson KC. Recombinant human TNF-related apoptosis inducing ligand (hu TRAIL) induces apoptosis of human multiple myeloma (MM) cells. Blood. 1998;92:634a.
    • (1998) Blood , vol.92
    • Treon, S.P.1    Chauhan, D.2    Raje, N.3    Teoh, G.4    Webb, I.5    Anderson, K.C.6
  • 19
    • 0031740779 scopus 로고    scopus 로고
    • Fas ligand is present in tumors of the Ewing's sarcoma family and is cleaved into a soluble form by a metalloproteinase
    • Mitsiades N, Poulaki V, Kotoula V, Leone A, Tsokos M. Fas ligand is present in tumors of the Ewing's sarcoma family and is cleaved into a soluble form by a metalloproteinase. Am J Pathol. 1998;153:1947-1956.
    • (1998) Am J Pathol , vol.153 , pp. 1947-1956
    • Mitsiades, N.1    Poulaki, V.2    Kotoula, V.3    Leone, A.4    Tsokos, M.5
  • 20
    • 0033558252 scopus 로고    scopus 로고
    • Muc-1 core protein is expressed on multiple myeloma cells and is induced by dexamethasone
    • Treon SP, Mollick JA, Urashima M, et al. Muc-1 core protein is expressed on multiple myeloma cells and is induced by dexamethasone. Blood. 1999;93:1287-1298.
    • (1999) Blood , vol.93 , pp. 1287-1298
    • Treon, S.P.1    Mollick, J.A.2    Urashima, M.3
  • 21
    • 0034330930 scopus 로고    scopus 로고
    • Elevated soluble MUC1 levels and decreased anti-MUC1 antibody levels in patients with multiple myeloma
    • Treon SP, Maimonis P, Bua D, et al. Elevated soluble MUC1 levels and decreased anti-MUC1 antibody levels in patients with multiple myeloma. Blood. 2000;96:3147-3153.
    • (2000) Blood , vol.96 , pp. 3147-3153
    • Treon, S.P.1    Maimonis, P.2    Bua, D.3
  • 22
    • 0032170090 scopus 로고    scopus 로고
    • Anti-estrogens induce apoptosis of multiple myeloma cells
    • Treon SP, Teoh G, Urashima M, et al. Anti-estrogens induce apoptosis of multiple myeloma cells. Blood. 1998;92:1749-1757.
    • (1998) Blood , vol.92 , pp. 1749-1757
    • Treon, S.P.1    Teoh, G.2    Urashima, M.3
  • 23
    • 0030294374 scopus 로고    scopus 로고
    • A mitochondrial membrane protein defined by a novel monoclonal antibody is preferentially detected in apoptotic cells
    • Zhang C, Ao Z, Seth A, Schlossman SF. A mitochondrial membrane protein defined by a novel monoclonal antibody is preferentially detected in apoptotic cells. J Immunol. 1996;157:3980-3987.
    • (1996) J Immunol , vol.157 , pp. 3980-3987
    • Zhang, C.1    Ao, Z.2    Seth, A.3    Schlossman, S.F.4
  • 24
    • 0031007485 scopus 로고    scopus 로고
    • Detection of apoptotic cells from peripheral blood of HIV-infected individuals using a novel monoclonal antibody
    • Seth A, Zhang C, Letvin NL, Schlossman SF. Detection of apoptotic cells from peripheral blood of HIV-infected individuals using a novel monoclonal antibody. AIDS. 1997;11:1059-1061.
    • (1997) AIDS , vol.11 , pp. 1059-1061
    • Seth, A.1    Zhang, C.2    Letvin, N.L.3    Schlossman, S.F.4
  • 25
    • 0027960892 scopus 로고
    • Interleukin-6 prevents dexamethasone-induced myeloma cell death
    • Hardin J, MacLeod S, Grigorieva I, et al. Interleukin-6 prevents dexamethasone-induced myeloma cell death. Blood. 1994;84:3063-3070.
    • (1994) Blood , vol.84 , pp. 3063-3070
    • Hardin, J.1    MacLeod, S.2    Grigorieva, I.3
  • 26
    • 0034623059 scopus 로고    scopus 로고
    • SHP2 mediates the protective effect of interleukin-6 against dexamethasone-induced apoptosis in multiple myeloma cells
    • Chauhan D, Pandey P, Hideshima T, et al. SHP2 mediates the protective effect of interleukin-6 against dexamethasone-induced apoptosis in multiple myeloma cells. J Biol Chem. 2000;275:27845-27850.
    • (2000) J Biol Chem , vol.275 , pp. 27845-27850
    • Chauhan, D.1    Pandey, P.2    Hideshima, T.3
  • 27
    • 0001458215 scopus 로고
    • Enzymes and metabolic inhibitors
    • Webb JL. Enzymes and metabolic inhibitors. Methods Enzymol. 1963;1:66-79.
    • (1963) Methods Enzymol , vol.1 , pp. 66-79
    • Webb, J.L.1
  • 28
    • 0031029911 scopus 로고    scopus 로고
    • Interleukin-6 inhibits Fas-induced apoptosis and stress-activated protein kinase activation in multiple myeloma cells
    • Chauhan D, Kharbanda S, Ogata A, et al. Interleukin-6 inhibits Fas-induced apoptosis and stress-activated protein kinase activation in multiple myeloma cells. Blood. 1997;89:227-234.
    • (1997) Blood , vol.89 , pp. 227-234
    • Chauhan, D.1    Kharbanda, S.2    Ogata, A.3
  • 29
    • 0027585687 scopus 로고
    • Growth characteristics of a human myeloma cell line transfected with IL-6 cDNA
    • Takahashi T, Okuno Y, Ohsugi Y. Growth characteristics of a human myeloma cell line transfected with IL-6 cDNA. Rinsho Ketsueki. 1993;34:423-426.
    • (1993) Rinsho Ketsueki , vol.34 , pp. 423-426
    • Takahashi, T.1    Okuno, Y.2    Ohsugi, Y.3
  • 31
    • 0033121314 scopus 로고    scopus 로고
    • Role of NF-kappa B in the rescue of multiple myeloma cells from glucocorticoid-induced apoptosis by bcl-2
    • Feinman R, Koury J, Thames M, Barlogie B, Epstein J, Siegel DS. Role of NF-kappa B in the rescue of multiple myeloma cells from glucocorticoid-induced apoptosis by bcl-2. Blood. 1999;93:3044-3052.
    • (1999) Blood , vol.93 , pp. 3044-3052
    • Feinman, R.1    Koury, J.2    Thames, M.3    Barlogie, B.4    Epstein, J.5    Siegel, D.S.6
  • 32
    • 0029006149 scopus 로고
    • Inhibition of nuclear translocation of transcription factor NF-kappa B by a synthetic peptide containing a cell membrane-permeable motif and nuclear localization sequence
    • Lin YZ, Yao SY, Veach RA, Torgerson TR, Hawiger J. Inhibition of nuclear translocation of transcription factor NF-kappa B by a synthetic peptide containing a cell membrane-permeable motif and nuclear localization sequence. J Biol Chem. 1995;270:14255-14258.
    • (1995) J Biol Chem , vol.270 , pp. 14255-14258
    • Lin, Y.Z.1    Yao, S.Y.2    Veach, R.A.3    Torgerson, T.R.4    Hawiger, J.5
  • 33
    • 0027980321 scopus 로고
    • The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B
    • Palombella VJ, Rando OJ, Goldberg AL, Maniatis T. The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B. Cell. 1994;78:773-785.
    • (1994) Cell , vol.78 , pp. 773-785
    • Palombella, V.J.1    Rando, O.J.2    Goldberg, A.L.3    Maniatis, T.4
  • 35
    • 0032717188 scopus 로고    scopus 로고
    • TRAIL is a potent inducer of apoptosis in myeloma cells derived from multiple myeloma patients and is not cytotoxic to hematopoietic stem cells
    • Gazitt Y. TRAIL is a potent inducer of apoptosis in myeloma cells derived from multiple myeloma patients and is not cytotoxic to hematopoietic stem cells. Leukemia. 1999;13:1817-1824.
    • (1999) Leukemia , vol.13 , pp. 1817-1824
    • Gazitt, Y.1
  • 36
    • 0033370411 scopus 로고    scopus 로고
    • Apoptosis-induced by TRAIL and TNF-alpha in human multiple myeloma cells is not blocked by BCL-2
    • Gazitt Y, Shaughnessy P, Montgomery W. Apoptosis-induced by TRAIL and TNF-alpha in human multiple myeloma cells is not blocked by BCL-2. Cytokine. 1999;11:1010-1019.
    • (1999) Cytokine , vol.11 , pp. 1010-1019
    • Gazitt, Y.1    Shaughnessy, P.2    Montgomery, W.3
  • 37
    • 0033210894 scopus 로고    scopus 로고
    • Selectivity of TRAIL-mediated apoptosis of cancer cells and synergy with drugs: The trail to non-toxic cancer therapeutics
    • Bonavida B, Ng CP, Jazirehi A, Schiller G, Mizutani Y. Selectivity of TRAIL-mediated apoptosis of cancer cells and synergy with drugs: the trail to non-toxic cancer therapeutics [review]. Int J Oncol. 1999;15:793-802.
    • (1999) Int J Oncol , vol.15 , pp. 793-802
    • Bonavida, B.1    Ng, C.P.2    Jazirehi, A.3    Schiller, G.4    Mizutani, Y.5
  • 38
    • 0031911838 scopus 로고    scopus 로고
    • Interleukin-6 in multiple myloma and related plasma cell dyscrasias
    • Treon SP, Anderson KC. Interleukin-6 in multiple myloma and related plasma cell dyscrasias. Curr Opin Hematol. 1998;5:42-48.
    • (1998) Curr Opin Hematol , vol.5 , pp. 42-48
    • Treon, S.P.1    Anderson, K.C.2
  • 39
    • 3543035176 scopus 로고    scopus 로고
    • Rare loss-of-function mutation of a death receptor gene in head and neck cancer
    • Pai SI, Wu GS, Ozoren N, et al. Rare loss-of-function mutation of a death receptor gene in head and neck cancer. Cancer Res. 1998;58:3513-3518.
    • (1998) Cancer Res , vol.58 , pp. 3513-3518
    • Pai, S.I.1    Wu, G.S.2    Ozoren, N.3
  • 40
    • 0001130662 scopus 로고    scopus 로고
    • Alterations of the DR5/TRAIL receptor 2 gene in non-small cell lung cancers
    • Lee SH, Shin MS, Kim HS, et al. Alterations of the DR5/TRAIL receptor 2 gene in non-small cell lung cancers. Cancer Res. 1999;59:5683-5686.
    • (1999) Cancer Res , vol.59 , pp. 5683-5686
    • Lee, S.H.1    Shin, M.S.2    Kim, H.S.3
  • 41
    • 0033104741 scopus 로고    scopus 로고
    • Functional analysis of TRAIL receptors using monoclonal antibodies
    • Griffith TS, Rauch CT, Smolak PJ, et al. Functional analysis of TRAIL receptors using monoclonal antibodies. J Immunol. 1999;162:2597-2605.
    • (1999) J Immunol , vol.162 , pp. 2597-2605
    • Griffith, T.S.1    Rauch, C.T.2    Smolak, P.J.3
  • 42
    • 0013583837 scopus 로고    scopus 로고
    • Relation of TNF-related apoptosis-inducing ligand (TRAIL) receptor and FLICE-inhibitory protein expression to TRAIL-induced apoptosis of melanoma
    • Zhang XD, Franco A, Myers K, Gray C, Nguyen T, Hersey P. Relation of TNF-related apoptosis-inducing ligand (TRAIL) receptor and FLICE-inhibitory protein expression to TRAIL-induced apoptosis of melanoma. Cancer Res. 1999;59:2747-2753.
    • (1999) Cancer Res , vol.59 , pp. 2747-2753
    • Zhang, X.D.1    Franco, A.2    Myers, K.3    Gray, C.4    Nguyen, T.5    Hersey, P.6
  • 43
    • 0033974084 scopus 로고    scopus 로고
    • Molecular determinants of response to TRAIL in killing of normal and cancer cells
    • Kim K, Fisher MJ, Xu SO, el-Deiry WS. Molecular determinants of response to TRAIL in killing of normal and cancer cells. Clin Cancer Res. 2000;6:335-346.
    • (2000) Clin Cancer Res , vol.6 , pp. 335-346
    • Kim, K.1    Fisher, M.J.2    Xu, S.O.3    El-Deiry, W.S.4
  • 44
    • 0000005230 scopus 로고    scopus 로고
    • Differential localization and regulation of death and decoy receptors for TNF-related apoptosis-inducing ligand (TRAIL) in human melanoma cells
    • Zhang XD, Franco AV, Nguyen T, Gray CP, Hersey P. Differential localization and regulation of death and decoy receptors for TNF-related apoptosis-inducing ligand (TRAIL) in human melanoma cells. J Immunol. 2000;164:3961-3970.
    • (2000) J Immunol , vol.164 , pp. 3961-3970
    • Zhang, X.D.1    Franco, A.V.2    Nguyen, T.3    Gray, C.P.4    Hersey, P.5
  • 45
    • 0030780188 scopus 로고    scopus 로고
    • PU. 1/Pip and basic helix loop helix zipper transcription factors interact with binding sites in the CD20 promoter to help confer lineage- and stage-specific expression of CD20 in B lymphocytes
    • Himmelmann A, Riva A, Wilson GL, Lucas BP, Thevenin C, Kehrl JH. PU.1/Pip and basic helix loop helix zipper transcription factors interact with binding sites in the CD20 promoter to help confer lineage- and stage-specific expression of CD20 in B lymphocytes. Blood. 1997;90:3984-3995.
    • (1997) Blood , vol.90 , pp. 3984-3995
    • Himmelmann, A.1    Riva, A.2    Wilson, G.L.3    Lucas, B.P.4    Thevenin, C.5    Kehrl, J.H.6
  • 46
    • 0034022160 scopus 로고    scopus 로고
    • Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand
    • Jo M, Kim TH, Seol DW, et al. Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand. Nat Med. 2000;6:564-567.
    • (2000) Nat Med , vol.6 , pp. 564-567
    • Jo, M.1    Kim, T.H.2    Seol, D.W.3
  • 47
    • 0034596514 scopus 로고    scopus 로고
    • Human brain-cell death induced by tumour-necrosis-factor-related apoptosis-inducing ligand (TRAIL)
    • Nitsch R, Bechmann I, Deisz RA, et al. Human brain-cell death induced by tumour-necrosis-factor-related apoptosis-inducing ligand (TRAIL) [letter]. Lancet. 2000;356:827-828.
    • (2000) Lancet , vol.356 , pp. 827-828
    • Nitsch, R.1    Bechmann, I.2    Deisz, R.A.3
  • 48
    • 0031253977 scopus 로고    scopus 로고
    • KILLER/DR5 is a DNA damage-inducible p53-regulated receptor gene
    • Wu GS, Burns TF, McDonald ERI, et al. KILLER/DR5 is a DNA damage-inducible p53-regulated receptor gene. Nat Genet. 1997;17:141-143.
    • (1997) Nat Genet , vol.17 , pp. 141-143
    • Wu, G.S.1    Burns, T.F.2    McDonald, E.R.I.3
  • 49
    • 0032522463 scopus 로고    scopus 로고
    • p53-dependent and -independent regulation of the death receptor KILLER/DR5 gene expression in response to genotoxic stress and tumor necrosis factor alpha
    • Sheikh MS, Burns TF, Huang Y, et al. p53-dependent and -independent regulation of the death receptor KILLER/DR5 gene expression in response to genotoxic stress and tumor necrosis factor alpha. Cancer Res. 1998;58:1593-1598.
    • (1998) Cancer Res , vol.58 , pp. 1593-1598
    • Sheikh, M.S.1    Burns, T.F.2    Huang, Y.3
  • 50
    • 0034652486 scopus 로고    scopus 로고
    • Increased death receptor 5 expression by chemotherapeutic agents in human gliomas causes synergistic cytotoxicity with tumor necrosis factor-related apoptosis-inducing ligand in vitro and in vivo
    • Nagane M, Pan G, Weddle JJ, Dixit VM, Cavenee WK, Huang HJ. Increased death receptor 5 expression by chemotherapeutic agents in human gliomas causes synergistic cytotoxicity with tumor necrosis factor-related apoptosis-inducing ligand in vitro and in vivo. Cancer Res. 2000;60:847-853.
    • (2000) Cancer Res , vol.60 , pp. 847-853
    • Nagane, M.1    Pan, G.2    Weddle, J.J.3    Dixit, V.M.4    Cavenee, W.K.5    Huang, H.J.6
  • 51
    • 0033989422 scopus 로고    scopus 로고
    • Increased expression of death receptors 4 and 5 synergizes the apoptosis response to combined treatment with etoposide and TRAIL
    • Gibson SB, Oyer R, Spalding AC, Anderson SM, Johnson GL. Increased expression of death receptors 4 and 5 synergizes the apoptosis response to combined treatment with etoposide and TRAIL. Mol Cell Biol. 2000;20:205-212.
    • (2000) Mol Cell Biol , vol.20 , pp. 205-212
    • Gibson, S.B.1    Oyer, R.2    Spalding, A.C.3    Anderson, S.M.4    Johnson, G.L.5
  • 52
    • 0032939903 scopus 로고    scopus 로고
    • Multiple signals converging on NF-kappa B
    • Mercurio F, Manning AM. Multiple signals converging on NF-kappa B. Curr Opin Cell Biol. 1999;11:226-232.
    • (1999) Curr Opin Cell Biol , vol.11 , pp. 226-232
    • Mercurio, F.1    Manning, A.M.2
  • 53
    • 0031406386 scopus 로고    scopus 로고
    • Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappa B pathway
    • Chaudhary PM, Eby M, Jasmin A, Bookwalter A, Murray J, Hood L. Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappa B pathway. Immunity. 1997;7:821-830.
    • (1997) Immunity , vol.7 , pp. 821-830
    • Chaudhary, P.M.1    Eby, M.2    Jasmin, A.3    Bookwalter, A.4    Murray, J.5    Hood, L.6
  • 54
    • 0031414749 scopus 로고    scopus 로고
    • The novel receptor TRAIL-R4 induces NF-kappa B and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain
    • Degli-Esposti MA, Dougall WC, Smolak PJ, Waugh JY, Smith CA, Goodwin RG. The novel receptor TRAIL-R4 induces NF-kappa B and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain. Immunity. 1997;7:813-820.
    • (1997) Immunity , vol.7 , pp. 813-820
    • Degli-Esposti, M.A.1    Dougall, W.C.2    Smolak, P.J.3    Waugh, J.Y.4    Smith, C.A.5    Goodwin, R.G.6
  • 55
    • 0032484009 scopus 로고    scopus 로고
    • TRAIL/Apo2L activates c-Jun NH2-terminal kinase (JNK) via caspase-dependent and caspase-independent pathways
    • Muhlenbeck F, Haas E, Schwenzer R, et al. TRAIL/Apo2L activates c-Jun NH2-terminal kinase (JNK) via caspase-dependent and caspase-independent pathways. J Biol Chem. 1998;273:33091-33098.
    • (1998) J Biol Chem , vol.273 , pp. 33091-33098
    • Muhlenbeck, F.1    Haas, E.2    Schwenzer, R.3
  • 56
    • 0031405585 scopus 로고    scopus 로고
    • TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-kappa B
    • Schneider P, Thorne M, Burns K, et al. TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-kappa B. Immunity. 1997;7:831-836.
    • (1997) Immunity , vol.7 , pp. 831-836
    • Schneider, P.1    Thorne, M.2    Burns, K.3
  • 57
    • 0033821215 scopus 로고    scopus 로고
    • The death domain kinase RIP is essential for TRAIL (Apo2L)-induced activation of IkappaB kinase and c-Jun N-Terminal kinase
    • Lin Y, Devin A, Cook A, et al. The death domain kinase RIP is essential for TRAIL (Apo2L)-induced activation of IkappaB kinase and c-Jun N-Terminal kinase. Mol Cell Biol. 2000;20:6638-6645.
    • (2000) Mol Cell Biol , vol.20 , pp. 6638-6645
    • Lin, Y.1    Devin, A.2    Cook, A.3
  • 58
    • 0034047091 scopus 로고    scopus 로고
    • Caffeic acid phenethyl ester induces leukocyte apoptosis, modulates nuclear factor-kappa B and suppresses acute inflammation
    • Orban Z, Mitsiades N, Burke TR Jr, Tsokos M, Chrousos GP. Caffeic acid phenethyl ester induces leukocyte apoptosis, modulates nuclear factor-kappa B and suppresses acute inflammation. Neuroimmunomodulation. 2000;7:99-105.
    • (2000) Neuroimmunomodulation , vol.7 , pp. 99-105
    • Orban, Z.1    Mitsiades, N.2    Burke T.R., Jr.3    Tsokos, M.4    Chrousos, G.P.5
  • 59
    • 0032905030 scopus 로고    scopus 로고
    • Control of inducible chemoresistance: Enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-kappa B
    • Wang CY, Cusack JC Jr, Liu R, Baldwin AS Jr. Control of inducible chemoresistance: enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-kappa B. Nat Med. 1999;5:412-417.
    • (1999) Nat Med , vol.5 , pp. 412-417
    • Wang, C.Y.1    Cusack J.C., Jr.2    Liu, R.3    Baldwin A.S., Jr.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.