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Volumn 56, Issue 1, 2014, Pages 97-106

Transcriptional and post-translational regulation of Bim controls apoptosis in melatonin-treated human renal cancer Caki cells

Author keywords

apoptosis; Bim; melatonin; proteasome activity; transcriptional regulation

Indexed keywords

BIM PROTEIN; MELATONIN; PROTEASOME; PROTEIN BCL 2; TRANSCRIPTION FACTOR E2F1; TRANSCRIPTION FACTOR SP1;

EID: 84890125260     PISSN: 07423098     EISSN: 1600079X     Source Type: Journal    
DOI: 10.1111/jpi.12102     Document Type: Article
Times cited : (38)

References (48)
  • 1
    • 79960360982 scopus 로고    scopus 로고
    • A survey of molecular details in the human pineal gland in the light of phylogeny, structure, function and chronobiological diseases
    • Stehle JH, Saade A, Rawashdeh O, et al. A survey of molecular details in the human pineal gland in the light of phylogeny, structure, function and chronobiological diseases. J Pineal Res 2011; 51: 17-43.
    • (2011) J Pineal Res , vol.51 , pp. 17-43
    • Stehle, J.H.1    Saade, A.2    Rawashdeh, O.3
  • 2
    • 84872685423 scopus 로고    scopus 로고
    • A review of the molecular aspects of melatonin's anti-inflammatory actions: Recent insights and new perspectives
    • Mauriz JL, Collado PS, Veneroso C, et al. A review of the molecular aspects of melatonin's anti-inflammatory actions: recent insights and new perspectives. J Pineal Res 2013; 54: 1-14.
    • (2013) J Pineal Res , vol.54 , pp. 1-14
    • Mauriz, J.L.1    Collado, P.S.2    Veneroso, C.3
  • 3
    • 79960380554 scopus 로고    scopus 로고
    • Melatonin as a natural ally against oxidative stress: A physicochemical examination
    • Galano A, Tan DX, Reiter RJ,. Melatonin as a natural ally against oxidative stress: a physicochemical examination. J Pineal Res 2011; 51: 1-16.
    • (2011) J Pineal Res , vol.51 , pp. 1-16
    • Galano, A.1    Tan, D.X.2    Reiter, R.J.3
  • 4
    • 79952573098 scopus 로고    scopus 로고
    • Reaction mechanism of melatonin oxidation by reactive oxygen species in vitro
    • Bonnefont-Rousselot D, Collin F, Jore D, et al. Reaction mechanism of melatonin oxidation by reactive oxygen species in vitro. J Pineal Res 2011; 50: 328-335.
    • (2011) J Pineal Res , vol.50 , pp. 328-335
    • Bonnefont-Rousselot, D.1    Collin, F.2    Jore, D.3
  • 5
    • 59649119052 scopus 로고    scopus 로고
    • Melatonin: An established antioxidant worthy of use in clinical trials
    • Korkmaz A, Reiter RJ, Topal T, et al. Melatonin: an established antioxidant worthy of use in clinical trials. Mol Med 2009; 15: 43-50.
    • (2009) Mol Med , vol.15 , pp. 43-50
    • Korkmaz, A.1    Reiter, R.J.2    Topal, T.3
  • 6
    • 77956301403 scopus 로고    scopus 로고
    • Melatonin induces pro-apoptotic signaling pathway in human pancreatic carcinoma cells (PANC-1)
    • Leja-Szpak A, Jaworek J, Pierzchalski P, et al. Melatonin induces pro-apoptotic signaling pathway in human pancreatic carcinoma cells (PANC-1). J Pineal Res 2010; 49: 248-255.
    • (2010) J Pineal Res , vol.49 , pp. 248-255
    • Leja-Szpak, A.1    Jaworek, J.2    Pierzchalski, P.3
  • 7
    • 84867744068 scopus 로고    scopus 로고
    • Melatonin inhibits cell proliferation and induces caspase activation and apoptosis in human malignant lymphoid cell lines
    • Sanchez-Hidalgo M, Lee M, de la Lastra CA, et al. Melatonin inhibits cell proliferation and induces caspase activation and apoptosis in human malignant lymphoid cell lines. J Pineal Res 2012; 53: 366-373.
    • (2012) J Pineal Res , vol.53 , pp. 366-373
    • Sanchez-Hidalgo, M.1    Lee, M.2    De La Lastra, C.A.3
  • 8
    • 84863602663 scopus 로고    scopus 로고
    • Simultaneous modulation of COX-2, p300, Akt, and Apaf-1 signaling by melatonin to inhibit proliferation and induce apoptosis in breast cancer cells
    • Wang J, Xiao X, Zhang Y, et al. Simultaneous modulation of COX-2, p300, Akt, and Apaf-1 signaling by melatonin to inhibit proliferation and induce apoptosis in breast cancer cells. J Pineal Res 2012; 53: 77-90.
    • (2012) J Pineal Res , vol.53 , pp. 77-90
    • Wang, J.1    Xiao, X.2    Zhang, Y.3
  • 9
    • 67649970221 scopus 로고    scopus 로고
    • Melatonin induces apoptotic death in LNCaP cells via p38 and JNK pathways: Therapeutic implications for prostate cancer
    • Joo SS, Yoo YM,. Melatonin induces apoptotic death in LNCaP cells via p38 and JNK pathways: therapeutic implications for prostate cancer. J Pineal Res 2009; 47: 8-14.
    • (2009) J Pineal Res , vol.47 , pp. 8-14
    • Joo, S.S.1    Yoo, Y.M.2
  • 10
    • 71549153554 scopus 로고    scopus 로고
    • Synergistic antitumor effect of melatonin with several chemotherapeutic drugs on human Ewing sarcoma cancer cells: Potentiation of the extrinsic apoptotic pathway
    • Casado-Zapico S, Rodriguez-Blanco J, Garcia-Santos G, et al. Synergistic antitumor effect of melatonin with several chemotherapeutic drugs on human Ewing sarcoma cancer cells: potentiation of the extrinsic apoptotic pathway. J Pineal Res 2010; 48: 72-80.
    • (2010) J Pineal Res , vol.48 , pp. 72-80
    • Casado-Zapico, S.1    Rodriguez-Blanco, J.2    Garcia-Santos, G.3
  • 11
    • 79954418375 scopus 로고    scopus 로고
    • Melatonin sensitizes Caki renal cancer cells to kahweol-induced apoptosis through CHOP-mediated up-regulation of PUMA
    • Um HJ, Park JW, Kwon TK,. Melatonin sensitizes Caki renal cancer cells to kahweol-induced apoptosis through CHOP-mediated up-regulation of PUMA. J Pineal Res 2011; 50: 359-366.
    • (2011) J Pineal Res , vol.50 , pp. 359-366
    • Um, H.J.1    Park, J.W.2    Kwon, T.K.3
  • 12
    • 26444483247 scopus 로고    scopus 로고
    • Protective effect of melatonin on paraquat-induced cytotoxicity in isolated rat hepatocytes
    • Garcia-Rubio L, Matas P, Miguez MP,. Protective effect of melatonin on paraquat-induced cytotoxicity in isolated rat hepatocytes. Hum Exp Toxicol 2005; 24: 475-480.
    • (2005) Hum Exp Toxicol , vol.24 , pp. 475-480
    • Garcia-Rubio, L.1    Matas, P.2    Miguez, M.P.3
  • 13
    • 0036229733 scopus 로고    scopus 로고
    • Protective effect of melatonin against cytotoxic actions of malondialdehyde: An in vitro study on human erythrocytes
    • Allegra M, Gentile C, Tesoriere L, et al. Protective effect of melatonin against cytotoxic actions of malondialdehyde: an in vitro study on human erythrocytes. J Pineal Res 2002; 32: 187-193.
    • (2002) J Pineal Res , vol.32 , pp. 187-193
    • Allegra, M.1    Gentile, C.2    Tesoriere, L.3
  • 14
    • 0036819494 scopus 로고    scopus 로고
    • Cytoprotection by melatonin and growth hormone in early rat myocardial infarction as revealed by Feulgen DNA staining
    • Castagnino HE, Lago N, Centrella JM, et al. Cytoprotection by melatonin and growth hormone in early rat myocardial infarction as revealed by Feulgen DNA staining. Neuro Endocrinol Lett 2002; 23: 391-395.
    • (2002) Neuro Endocrinol Lett , vol.23 , pp. 391-395
    • Castagnino, H.E.1    Lago, N.2    Centrella, J.M.3
  • 15
    • 83555173352 scopus 로고    scopus 로고
    • Melatonin alleviates cadmium-induced cellular stress and germ cell apoptosis in testes
    • Ji YL, Wang H, Meng C, et al. Melatonin alleviates cadmium-induced cellular stress and germ cell apoptosis in testes. J Pineal Res 2012; 52: 71-79.
    • (2012) J Pineal Res , vol.52 , pp. 71-79
    • Ji, Y.L.1    Wang, H.2    Meng, C.3
  • 16
    • 37549048249 scopus 로고    scopus 로고
    • The BCL-2 protein family: Opposing activities that mediate cell death
    • Youle RJ, Strasser A,. The BCL-2 protein family: opposing activities that mediate cell death. Nat Rev Mol Cell Biol 2008; 9: 47-59.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 47-59
    • Youle, R.J.1    Strasser, A.2
  • 17
    • 54949132875 scopus 로고    scopus 로고
    • Bcl-2 family proteins and cancer
    • Yip KW, Reed JC,. Bcl-2 family proteins and cancer. Oncogene 2008; 27: 6398-6406.
    • (2008) Oncogene , vol.27 , pp. 6398-6406
    • Yip, K.W.1    Reed, J.C.2
  • 18
    • 0037089068 scopus 로고    scopus 로고
    • BH3-only proteins - Evolutionarily conserved proapoptotic Bcl-2 family members essential for initiating programmed cell death
    • Bouillet P, Strasser A,. BH3-only proteins-evolutionarily conserved proapoptotic Bcl-2 family members essential for initiating programmed cell death. J Cell Sci 2002; 115: 1567-1574.
    • (2002) J Cell Sci , vol.115 , pp. 1567-1574
    • Bouillet, P.1    Strasser, A.2
  • 19
    • 0034502157 scopus 로고    scopus 로고
    • The role of the pro-apoptotic Bcl-2 family member bim in physiological cell death
    • Bouillet P, Huang DC, O'reilly LA, et al. The role of the pro-apoptotic Bcl-2 family member bim in physiological cell death. Ann N Y Acad Sci 2000; 926: 83-89.
    • (2000) Ann N y Acad Sci , vol.926 , pp. 83-89
    • Bouillet, P.1    Huang, D.C.2    O'Reilly, L.A.3
  • 20
    • 0033665032 scopus 로고    scopus 로고
    • The role of bim, a proapoptotic BH3-only member of the Bcl-2 family in cell-death control
    • Strasser A, Puthalakath H, Bouillet P, et al. The role of bim, a proapoptotic BH3-only member of the Bcl-2 family in cell-death control. Ann N Y Acad Sci 2000; 917: 541-548.
    • (2000) Ann N y Acad Sci , vol.917 , pp. 541-548
    • Strasser, A.1    Puthalakath, H.2    Bouillet, P.3
  • 21
    • 0042477712 scopus 로고    scopus 로고
    • FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons
    • Gilley J, Coffer PJ, Ham J,. FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons. J Cell Biol 2003; 162: 613-622.
    • (2003) J Cell Biol , vol.162 , pp. 613-622
    • Gilley, J.1    Coffer, P.J.2    Ham, J.3
  • 22
    • 33845965024 scopus 로고    scopus 로고
    • Cytokines direct the regulation of Bim mRNA stability by heat-shock cognate protein 70
    • Matsui H, Asou H, Inaba T,. Cytokines direct the regulation of Bim mRNA stability by heat-shock cognate protein 70. Mol Cell 2007; 25: 99-112.
    • (2007) Mol Cell , vol.25 , pp. 99-112
    • Matsui, H.1    Asou, H.2    Inaba, T.3
  • 23
    • 43449132366 scopus 로고    scopus 로고
    • Multisite phosphorylation regulates Bim stability and apoptotic activity
    • Hubner A, Barrett T, Flavell RA, et al. Multisite phosphorylation regulates Bim stability and apoptotic activity. Mol Cell 2008; 30: 415-425.
    • (2008) Mol Cell , vol.30 , pp. 415-425
    • Hubner, A.1    Barrett, T.2    Flavell, R.A.3
  • 24
    • 0038482050 scopus 로고    scopus 로고
    • Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim
    • Ley R, Balmanno K, Hadfield K, et al. Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim. J Biol Chem 2003; 278: 18811-18816.
    • (2003) J Biol Chem , vol.278 , pp. 18811-18816
    • Ley, R.1    Balmanno, K.2    Hadfield, K.3
  • 25
    • 0035124927 scopus 로고    scopus 로고
    • Gene structure alternative splicing, and chromosomal localization of pro-apoptotic Bcl-2 relative Bim
    • Bouillet P, Zhang LC, Huang DC, et al. Gene structure alternative splicing, and chromosomal localization of pro-apoptotic Bcl-2 relative Bim. Mamm Genome 2001; 12: 163-168.
    • (2001) Mamm Genome , vol.12 , pp. 163-168
    • Bouillet, P.1    Zhang, L.C.2    Huang, D.C.3
  • 26
    • 84873743356 scopus 로고    scopus 로고
    • Melatonin induces transcriptional regulation of Bim by FoxO3a in HepG2 cells
    • Carbajo-Pescador S, Steinmetz C, Kashyap A, et al. Melatonin induces transcriptional regulation of Bim by FoxO3a in HepG2 cells. Br J Cancer 2013; 108: 442-449.
    • (2013) Br J Cancer , vol.108 , pp. 442-449
    • Carbajo-Pescador, S.1    Steinmetz, C.2    Kashyap, A.3
  • 27
    • 79956188245 scopus 로고    scopus 로고
    • Sphingosine kinase 1 regulates the Akt/FOXO3a/Bim pathway and contributes to apoptosis resistance in glioma cells
    • Guan H, Song L, Cai J, et al. Sphingosine kinase 1 regulates the Akt/FOXO3a/Bim pathway and contributes to apoptosis resistance in glioma cells. PLoS ONE 2011; 6: e19946.
    • (2011) PLoS ONE , vol.6
    • Guan, H.1    Song, L.2    Cai, J.3
  • 28
    • 1542305653 scopus 로고    scopus 로고
    • Up-regulation of Bcl-2 homology 3 (BH3)-only proteins by E2F1 mediates apoptosis
    • Hershko T, Ginsberg D,. Up-regulation of Bcl-2 homology 3 (BH3)-only proteins by E2F1 mediates apoptosis. J Biol Chem 2004; 279: 8627-8634.
    • (2004) J Biol Chem , vol.279 , pp. 8627-8634
    • Hershko, T.1    Ginsberg, D.2
  • 29
    • 4444311881 scopus 로고    scopus 로고
    • Simultaneous inhibition of hsp 90 and the proteasome promotes protein ubiquitination, causes endoplasmic reticulum-derived cytosolic vacuolization, and enhances antitumor activity
    • Mimnaugh EG, Xu W, Vos M, et al. Simultaneous inhibition of hsp 90 and the proteasome promotes protein ubiquitination, causes endoplasmic reticulum-derived cytosolic vacuolization, and enhances antitumor activity. Mol Cancer Ther 2004; 3: 551-566.
    • (2004) Mol Cancer Ther , vol.3 , pp. 551-566
    • Mimnaugh, E.G.1    Xu, W.2    Vos, M.3
  • 30
    • 0242521470 scopus 로고    scopus 로고
    • Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function
    • Luciano F, Jacquel A, Colosetti P, et al. Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function. Oncogene 2003; 22: 6785-6793.
    • (2003) Oncogene , vol.22 , pp. 6785-6793
    • Luciano, F.1    Jacquel, A.2    Colosetti, P.3
  • 31
    • 84863730090 scopus 로고    scopus 로고
    • Recent progress in the development of agonists and antagonists for melatonin receptors
    • Zlotos DP,. Recent progress in the development of agonists and antagonists for melatonin receptors. Curr Med Chem 2012; 19: 3532-3549.
    • (2012) Curr Med Chem , vol.19 , pp. 3532-3549
    • Zlotos, D.P.1
  • 32
    • 46749097473 scopus 로고    scopus 로고
    • Physiological effects of melatonin: Role of melatonin receptors and signal transduction pathways
    • Pandi-Perumal SR, Trakht I, Srinivasan V, et al. Physiological effects of melatonin: role of melatonin receptors and signal transduction pathways. Prog Neurobiol 2008; 85: 335-353.
    • (2008) Prog Neurobiol , vol.85 , pp. 335-353
    • Pandi-Perumal, S.R.1    Trakht, I.2    Srinivasan, V.3
  • 33
    • 84862830150 scopus 로고    scopus 로고
    • Melatonin sensitizes human hepatoma cells to endoplasmic reticulum stress-induced apoptosis
    • Zha L, Fan L, Sun G, et al. Melatonin sensitizes human hepatoma cells to endoplasmic reticulum stress-induced apoptosis. J Pineal Res 2012; 52: 322-331.
    • (2012) J Pineal Res , vol.52 , pp. 322-331
    • Zha, L.1    Fan, L.2    Sun, G.3
  • 34
    • 84856756338 scopus 로고    scopus 로고
    • Melatonin synergistically enhances cisplatin-induced apoptosis via the dephosphorylation of ERK/p90 ribosomal S6 kinase/heat shock protein 27 in SK-OV-3 cells
    • Kim JH, Jeong SJ, Kim B, et al. Melatonin synergistically enhances cisplatin-induced apoptosis via the dephosphorylation of ERK/p90 ribosomal S6 kinase/heat shock protein 27 in SK-OV-3 cells. J Pineal Res 2012; 52: 244-252.
    • (2012) J Pineal Res , vol.52 , pp. 244-252
    • Kim, J.H.1    Jeong, S.J.2    Kim, B.3
  • 35
    • 77950838898 scopus 로고    scopus 로고
    • Melatonin and doxorubicin synergistically induce cell apoptosis in human hepatoma cell lines
    • Fan LL, Sun GP, Wei W, et al. Melatonin and doxorubicin synergistically induce cell apoptosis in human hepatoma cell lines. World J Gastroenterol 2010; 16: 1473-1481.
    • (2010) World J Gastroenterol , vol.16 , pp. 1473-1481
    • Fan, L.L.1    Sun, G.P.2    Wei, W.3
  • 36
    • 67649595826 scopus 로고    scopus 로고
    • Apoptosis and cancer: The genesis of a research field
    • Cotter TG,. Apoptosis and cancer: the genesis of a research field. Nat Rev Cancer 2009; 9: 501-507.
    • (2009) Nat Rev Cancer , vol.9 , pp. 501-507
    • Cotter, T.G.1
  • 37
  • 38
    • 10744230034 scopus 로고    scopus 로고
    • FoxO3a transcriptional regulation of Bim controls apoptosis in paclitaxel-treated breast cancer cell lines
    • Sunters A, Fernandez de Mattos S, Stahl M, et al. FoxO3a transcriptional regulation of Bim controls apoptosis in paclitaxel-treated breast cancer cell lines. J Biol Chem 2003; 278: 49795-49805.
    • (2003) J Biol Chem , vol.278 , pp. 49795-49805
    • Sunters, A.1    Fernandez De Mattos, S.2    Stahl, M.3
  • 39
    • 20444497875 scopus 로고    scopus 로고
    • FOXO-dependent expression of the proapoptotic protein Bim: Pivotal role for apoptosis signaling in endothelial progenitor cells
    • Urbich C, Knau A, Fichtlscherer S, et al. FOXO-dependent expression of the proapoptotic protein Bim: pivotal role for apoptosis signaling in endothelial progenitor cells. FASEB J 2005; 19: 974-976.
    • (2005) FASEB J , vol.19 , pp. 974-976
    • Urbich, C.1    Knau, A.2    Fichtlscherer, S.3
  • 40
    • 0037036451 scopus 로고    scopus 로고
    • Identification of two Sp1 phosphorylation sites for p42/p44 mitogen-activated protein kinases: Their implication in vascular endothelial growth factor gene transcription
    • Milanini-Mongiat J, Pouyssegur J, Pages G,. Identification of two Sp1 phosphorylation sites for p42/p44 mitogen-activated protein kinases: their implication in vascular endothelial growth factor gene transcription. J Biol Chem 2002; 277: 20631-20639.
    • (2002) J Biol Chem , vol.277 , pp. 20631-20639
    • Milanini-Mongiat, J.1    Pouyssegur, J.2    Pages, G.3
  • 41
    • 33744539154 scopus 로고    scopus 로고
    • Apoptosis signal-regulating kinase 1 is a direct target of E2F1 and contributes to histone deacetylase inhibitor-induced apoptosis through positive feedback regulation of E2F1 apoptotic activity
    • Tan J, Zhuang L, Jiang X, et al. Apoptosis signal-regulating kinase 1 is a direct target of E2F1 and contributes to histone deacetylase inhibitor-induced apoptosis through positive feedback regulation of E2F1 apoptotic activity. J Biol Chem 2006; 281: 10508-10515.
    • (2006) J Biol Chem , vol.281 , pp. 10508-10515
    • Tan, J.1    Zhuang, L.2    Jiang, X.3
  • 42
    • 36849034462 scopus 로고    scopus 로고
    • Melatonin, endocrine pancreas and diabetes
    • Peschke E,. Melatonin, endocrine pancreas and diabetes. J Pineal Res 2008; 44: 26-40.
    • (2008) J Pineal Res , vol.44 , pp. 26-40
    • Peschke, E.1
  • 44
    • 36849090114 scopus 로고    scopus 로고
    • Epigenetic regulation: A new research area for melatonin?
    • Korkmaz A, Reiter RJ,. Epigenetic regulation: a new research area for melatonin? J Pineal Res 2008; 44: 41-44.
    • (2008) J Pineal Res , vol.44 , pp. 41-44
    • Korkmaz, A.1    Reiter, R.J.2
  • 45
    • 63549107569 scopus 로고    scopus 로고
    • Melatonin present in beer contributes to increase the levels of melatonin and antioxidant capacity of the human serum
    • Maldonado MD, Moreno H, Calvo JR,. Melatonin present in beer contributes to increase the levels of melatonin and antioxidant capacity of the human serum. Clin Nutr 2009; 28: 188-191.
    • (2009) Clin Nutr , vol.28 , pp. 188-191
    • Maldonado, M.D.1    Moreno, H.2    Calvo, J.R.3
  • 46
    • 0030945110 scopus 로고    scopus 로고
    • Variable bioavailability of oral melatonin
    • Di WL, Kadva A, Johnston A, et al. Variable bioavailability of oral melatonin. N Engl J Med 1997; 336: 1028-1029.
    • (1997) N Engl J Med , vol.336 , pp. 1028-1029
    • Di, W.L.1    Kadva, A.2    Johnston, A.3
  • 47
    • 33749347001 scopus 로고    scopus 로고
    • Reduced oxidative damage in ALS by high-dose enteral melatonin treatment
    • Weishaupt JH, Bartels C, Polking E, et al. Reduced oxidative damage in ALS by high-dose enteral melatonin treatment. J Pineal Res 2006; 41: 313-323.
    • (2006) J Pineal Res , vol.41 , pp. 313-323
    • Weishaupt, J.H.1    Bartels, C.2    Polking, E.3
  • 48
    • 0023149121 scopus 로고
    • Influence of chronic melatonin on 9,10-dimethyl-1,2-benzanthracene- induced mammary tumors in female Holtzman rats exposed to continuous light
    • Kothari LS,. Influence of chronic melatonin on 9,10-dimethyl-1,2- benzanthracene-induced mammary tumors in female Holtzman rats exposed to continuous light. Oncology 1987; 44: 64-66.
    • (1987) Oncology , vol.44 , pp. 64-66
    • Kothari, L.S.1


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