Melatonin enhances alkaline phosphatase activity in differentiating human adult mesenchymal stem cells grown in osteogenic medium via MT2 melatonin receptors and the MEK/ERK (1/2) signaling cascade

Journal of Pineal Research

Volumn 40, Issue 4, 2006, Pages 332-342

  Radio, Nicholas M ^a   Doctor, John S ^a   Witt Enderby, Paula A ^a  

^a DUQUESNE UNIVERSITY   (United States)

Author keywords

MEK ERK 1 2; Melatonin; Melatonin receptors; Mesenchymal stem cells; Osteoblasts

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ALKALINE PHOSPHATASE; CLATHRIN; DANSYLCADAVERINE; EPIDERMAL GROWTH FACTOR RECEPTOR; FORSKOLIN; ILOMASTAT; KT 5720; LUZINDOLE; MELATONIN; MELATONIN 2 RECEPTOR; MELATONIN RECEPTOR 2 ANTAGONIST; MELATONIN RECEPTOR ANTAGONIST; METALLOPROTEINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE; N [4 (3 BROMOANILINO) 6 QUINAZOLINYL]ACRYLAMIDE; PERTUSSIS TOXIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CELL DIFFERENTIATION; CELL GROWTH; CONTROLLED STUDY; CULTURE MEDIUM; ENDOCYTOSIS; ENZYME ACTIVITY; HORMONE ACTION; HORMONE RECEPTOR INTERACTION; HUMAN; HUMAN CELL; HUMAN TISSUE; MESENCHYMAL STEM CELL; OSTEOBLAST; OSTEOPOROSIS; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION;

ADULT; ALKALINE PHOSPHATASE; BLOTTING, WESTERN; CULTURE MEDIA; CYCLIC AMP; HUMANS; MELATONIN; MESENCHYMAL STEM CELLS; MITOGEN-ACTIVATED PROTEIN KINASES; RECEPTORS, MELATONIN; SIGNAL TRANSDUCTION;

EID: 33645473088     PISSN: 07423098     EISSN: 1600079X     Source Type: Journal    
DOI: 10.1111/j.1600-079X.2006.00318.x     Document Type: Article

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