Melatonin stimulates antioxidant enzymes and reduces oxidative stress in experimental traumatic brain injury: The Nrf2-ARE signaling pathway as a potential mechanism

Free Radical Biology and Medicine

Volumn 73, Issue , 2014, Pages 1-11

  Ding, Ke ^a   Wang, Handong ^a   Xu, Jianguo ^a   Li, Tao ^a   Zhang, Li ^a   Ding, Yu ^a   Zhu, Lin ^a   He, Jin ^a   Zhou, Mengliang ^a  

^a NANJING UNIVERSITY   (China)

Author keywords

Antioxidant enzymes; Free radicals; Melatonin; Nuclear factor erythroid 2 related factor 2; Signaling pathway; Traumatic brain injury

Indexed keywords

GLUTATHIONE PEROXIDASE; HEME OXYGENASE 1; MELATONIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR NRF2; HMOX1 PROTEIN, MOUSE; MEMBRANE PROTEIN; NEUROPROTECTIVE AGENT; NFE2L2 PROTEIN, MOUSE; NQO1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; BRAIN EDEMA; CONTROLLED STUDY; CYTOPLASM; ENZYME ACTIVITY; EXPERIMENTAL DISEASE; EXPERIMENTAL MODEL; EXPERIMENTAL TRAUMATIC BRAIN INJURY; MALE; MOUSE; NERVE CELL DEGENERATION; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRAUMATIC BRAIN INJURY; WILD TYPE; ACTIVE TRANSPORT; ANIMAL; BIOSYNTHESIS; BRAIN INJURIES; DRUG EFFECTS; GENETICS; INSTITUTE FOR CANCER RESEARCH MOUSE; KNOCKOUT MOUSE; METABOLISM; SIGNAL TRANSDUCTION; UPREGULATION;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; ANTIOXIDANT RESPONSE ELEMENTS; BRAIN EDEMA; BRAIN INJURIES; GLUTATHIONE PEROXIDASE; HEME OXYGENASE-1; MALE; MELATONIN; MEMBRANE PROTEINS; MICE; MICE, INBRED ICR; MICE, KNOCKOUT; NAD(P)H DEHYDROGENASE (QUINONE); NEUROPROTECTIVE AGENTS; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; SIGNAL TRANSDUCTION; SUPEROXIDE DISMUTASE; UP-REGULATION;

EID: 84901328016     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2014.04.031     Document Type: Article

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