메뉴 건너뛰기




Volumn 46, Issue 2, 2009, Pages 172-180

Evidence for a biphasic apoptotic pathway induced by melatonin in MCF-7 breast cancer cells

Author keywords

Apoptosis; Apoptotic inducing factor; Breast cancer; Cleaved poly ADP ribose polymerase; Melatonin; Murine double minute 2; Transforming growth factor beta 1

Indexed keywords

CASPASE 6; CASPASE 7; CASPASE 9; MELATONIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN MDM2; PROTEIN P53; PROTEIN P73; TRANSFORMING GROWTH FACTOR BETA1;

EID: 59149104957     PISSN: 07423098     EISSN: 1600079X     Source Type: Journal    
DOI: 10.1111/j.1600-079X.2008.00645.x     Document Type: Article
Times cited : (106)

References (32)
  • 1
    • 0037844514 scopus 로고    scopus 로고
    • The role of pineal gland in breast cancer development
    • Anisimov VN. The role of pineal gland in breast cancer development. Crit Rev Oncol Hematol 2003 46 : 221 234.
    • (2003) Crit Rev Oncol Hematol , vol.46 , pp. 221-234
    • Anisimov, V.N.1
  • 3
    • 0022498928 scopus 로고
    • Effects of melatonin on cancer: Studies on MCF-7 human breast cancer cells in culture
    • Blask DE, Hill SM. Effects of melatonin on cancer: studies on MCF-7 human breast cancer cells in culture. J Neural Transm 1986 21 : 433 449.
    • (1986) J Neural Transm , vol.21 , pp. 433-449
    • Blask, D.E.1    Hill, S.M.2
  • 4
    • 0023698530 scopus 로고
    • Effects of the pineal hormone melatonin on the proliferation and morphological characteristics of human breast cancer cells (MCF-7) in culture
    • Hill SM, Blask DE. Effects of the pineal hormone melatonin on the proliferation and morphological characteristics of human breast cancer cells (MCF-7) in culture. Cancer Res 1988 48 : 6121 6126.
    • (1988) Cancer Res , vol.48 , pp. 6121-6126
    • Hill, S.M.1    Blask, D.E.2
  • 5
    • 0028490843 scopus 로고
    • Melatonin modulates growth factor activity in MCF-7 human breast cancer cells
    • Cos S, Blask DE. Melatonin modulates growth factor activity in MCF-7 human breast cancer cells. J Pineal Res 1994 17 : 25 32.
    • (1994) J Pineal Res , vol.17 , pp. 25-32
    • Cos, S.1    Blask, D.E.2
  • 6
    • 0028981509 scopus 로고
    • Melatonin inhibition of MCF-7 human breast cancer cells: Influence of cell proliferation rate
    • Cos S, Recio J, Sanchez-Barcelo EJ. Melatonin inhibition of MCF-7 human breast cancer cells: influence of cell proliferation rate. Cancer Lett 1995 93 : 207 212.
    • (1995) Cancer Lett , vol.93 , pp. 207-212
    • Cos, S.1    Recio, J.2    Sanchez-Barcelo, E.J.3
  • 7
    • 0034013429 scopus 로고    scopus 로고
    • Differential responsiveness of MCF-7 human breast cancer cell line stoks to the pineal hormone melatonin
    • Ram PT, Yuan L, Dai J et al. Differential responsiveness of MCF-7 human breast cancer cell line stoks to the pineal hormone melatonin. J Pineal Res 2000 28 : 210 218.
    • (2000) J Pineal Res , vol.28 , pp. 210-218
    • Ram, P.T.1    Yuan, L.2    Dai, J.3
  • 8
    • 0032565919 scopus 로고    scopus 로고
    • Estrogen receptor transactivation in MCF-7 breast cancer cells by melatonin and growth factors
    • Ram PT, Kiefer T, Silverman M et al. Estrogen receptor transactivation in MCF-7 breast cancer cells by melatonin and growth factors. Mol Cell Endocrinol 1998 141 : 53 64.
    • (1998) Mol Cell Endocrinol , vol.141 , pp. 53-64
    • Ram, P.T.1    Kiefer, T.2    Silverman, M.3
  • 9
    • 0033695227 scopus 로고    scopus 로고
    • Antiproliferative effect and cell cycle modulation by melatonin on GH(3) cells
    • Fornas O, Mato ME, Webb SM. Antiproliferative effect and cell cycle modulation by melatonin on GH(3) cells. Horm Res 2000 53 : 251 255.
    • (2000) Horm Res , vol.53 , pp. 251-255
    • Fornas, O.1    Mato, M.E.2    Webb, S.M.3
  • 10
    • 0042913095 scopus 로고    scopus 로고
    • Melatonin inhibits telomerase activity in the MCF-7 tumor cell line both in vivo and in vitro
    • Leon-Blanco MM, Guerrero JM, Reiter RJ et al. Melatonin inhibits telomerase activity in the MCF-7 tumor cell line both in vivo and in vitro. J Pineal Res 2003 35 : 204 211.
    • (2003) J Pineal Res , vol.35 , pp. 204-211
    • Leon-Blanco, M.M.1    Guerrero, J.M.2    Reiter, R.J.3
  • 11
    • 0033820053 scopus 로고    scopus 로고
    • Melatonin effects on intercellular junctional communication in MCF-7 human breast cancer cells
    • Cos S, Fernandez R. Melatonin effects on intercellular junctional communication in MCF-7 human breast cancer cells. J Pineal Res 2000 29 : 166 171.
    • (2000) J Pineal Res , vol.29 , pp. 166-171
    • Cos, S.1    Fernandez, R.2
  • 12
    • 22044439575 scopus 로고    scopus 로고
    • Antiproliferative activity of melatonin by transcriptional inhibition of cyclin D1 expression: A molecular basis for melatonin-induced effects
    • Cini G, Neri B, Pacini A et al. Antiproliferative activity of melatonin by transcriptional inhibition of cyclin D1 expression: a molecular basis for melatonin-induced effects. J Pineal Res 2005 39 : 12 20.
    • (2005) J Pineal Res , vol.39 , pp. 12-20
    • Cini, G.1    Neri, B.2    Pacini, A.3
  • 13
    • 36849090114 scopus 로고    scopus 로고
    • Epigenetic regulation: A new research area for melatonin?
    • Korkmaz A, Reiter RJ. Epigenetic regulation: a new research area for melatonin? J Pineal Res 2008 44 : 41 44.
    • (2008) J Pineal Res , vol.44 , pp. 41-44
    • Korkmaz, A.1    Reiter, R.J.2
  • 14
    • 0038209091 scopus 로고    scopus 로고
    • 1 release and induce growth inhibition in breast cancer cell cultures
    • 1 release and induce growth inhibition in breast cancer cell cultures. J Surg Res 2003 110 : 332 337.
    • (2003) J Surg Res , vol.110 , pp. 332-337
    • Bizzarri, M.1    Cucina, A.2    Valente, M.G.3
  • 15
    • 0042869981 scopus 로고    scopus 로고
    • Melatonin and cell death: Differential actions on apoptosis in normal and cancer cells
    • Sainz RM, Mayo JC, Rodriguez C et al. Melatonin and cell death: differential actions on apoptosis in normal and cancer cells. Cell Mol Life Sci 2003 60 : 1407 1426.
    • (2003) Cell Mol Life Sci , vol.60 , pp. 1407-1426
    • Sainz, R.M.1    Mayo, J.C.2    Rodriguez, C.3
  • 16
    • 34848919892 scopus 로고    scopus 로고
    • Melatonin protects against common deletion of mitochondrial DNA-augmented mitochondrial oxidative stress and apoptosis
    • Jou MJ, Peng TI, Yu PZ et al. Melatonin protects against common deletion of mitochondrial DNA-augmented mitochondrial oxidative stress and apoptosis. J Pineal Res 2007 43 : 389 403.
    • (2007) J Pineal Res , vol.43 , pp. 389-403
    • Jou, M.J.1    Peng, T.I.2    Yu, P.Z.3
  • 17
    • 33749365523 scopus 로고    scopus 로고
    • Melatonin modulates signal transduction pathways and apoptosis in experimental colitis
    • Mazzon E, Esposito E, Crisafulli C et al. Melatonin modulates signal transduction pathways and apoptosis in experimental colitis. J Pineal Res 2006 41 : 363 373.
    • (2006) J Pineal Res , vol.41 , pp. 363-373
    • Mazzon, E.1    Esposito, E.2    Crisafulli, C.3
  • 18
    • 27744592273 scopus 로고    scopus 로고
    • Melatonin provokes cell death in human B-lymphoma cells by mitochondrial-dependent apoptotic pathway activation
    • Trubiani O, Recchioni R, Moroni F et al. Melatonin provokes cell death in human B-lymphoma cells by mitochondrial-dependent apoptotic pathway activation. J Pineal Res 2005 39 : 425 431.
    • (2005) J Pineal Res , vol.39 , pp. 425-431
    • Trubiani, O.1    Recchioni, R.2    Moroni, F.3
  • 19
    • 0031761543 scopus 로고    scopus 로고
    • Somatostatin analogue octreotide and melatonin inhibit bromodeoxyuridine incorporation into cell nuclei and enhance apoptosis in the transplantable murine colon 38 cancer
    • Melen-Mucha G, Winczyk K, Pawlikowski M. Somatostatin analogue octreotide and melatonin inhibit bromodeoxyuridine incorporation into cell nuclei and enhance apoptosis in the transplantable murine colon 38 cancer. Anticancer Res 1998 18 5A 3615 3620.
    • (1998) Anticancer Res , vol.18 , Issue.5 , pp. 3615-3620
    • Melen-Mucha, G.1    Winczyk, K.2    Pawlikowski, M.3
  • 20
    • 0036214251 scopus 로고    scopus 로고
    • Does melatonin induce apoptosis in MCF-7 human breast cancer cells in vitro?
    • Cos S, Mediavilla MD, Fernandez R et al. Does melatonin induce apoptosis in MCF-7 human breast cancer cells in vitro? J Pineal Res 2002 32 : 90 96.
    • (2002) J Pineal Res , vol.32 , pp. 90-96
    • Cos, S.1    Mediavilla, M.D.2    Fernandez, R.3
  • 21
    • 0025828360 scopus 로고
    • Effects of melatonin on the cell cycle kinetics and 'estrogen rescue' of MCF-7 human breast cancer cells in culture
    • Cos S, Blask DE, Lemus-Wilson A, Hill AB. Effects of melatonin on the cell cycle kinetics and 'estrogen rescue' of MCF-7 human breast cancer cells in culture. J Pineal Res 1991 10 : 36 43.
    • (1991) J Pineal Res , vol.10 , pp. 36-43
    • Cos, S.1    Blask, D.E.2    Lemus-Wilson, A.3    Hill, A.B.4
  • 22
    • 0028572548 scopus 로고
    • Modulation of estrogen receptor mRNA expression by melatonin in MCF-7 human breast cancer cells
    • Molis TM, Spriggs LL, Hill SM. Modulation of estrogen receptor mRNA expression by melatonin in MCF-7 human breast cancer cells. Mol Endocrinol 1994 8 : 1683 1690.
    • (1994) Mol Endocrinol , vol.8 , pp. 1683-1690
    • Molis, T.M.1    Spriggs, L.L.2    Hill, S.M.3
  • 23
    • 4644305480 scopus 로고    scopus 로고
    • 1 and retinoids modify the acivity of estradiol and antiestrogens in MCF-7 breast cancer cells?
    • 1 and retinoids modify the acivity of estradiol and antiestrogens in MCF-7 breast cancer cells? Acta Biochim Pol 2004 51 : 733 745.
    • (2004) Acta Biochim Pol , vol.51 , pp. 733-745
    • Czeczuga-Semeniuk, E.1    Anchim, T.2    Dzieciol, J.3
  • 24
    • 0031777590 scopus 로고    scopus 로고
    • A sequential treatment regimen with melatonin and all-trans retinoic acid induces apoptosis in MCF-7 tumour cells
    • Eck KM, Yuan L, Duffy L et al. A sequential treatment regimen with melatonin and all-trans retinoic acid induces apoptosis in MCF-7 tumour cells. Br J Cancer 1998 77 : 2129 2137.
    • (1998) Br J Cancer , vol.77 , pp. 2129-2137
    • Eck, K.M.1    Yuan, L.2    Duffy, L.3
  • 25
    • 0036511127 scopus 로고    scopus 로고
    • Karyotypic variation between independently cultured strains of the cell line MCF-7 identified by multicolour fluorescence in situ hybridization
    • Bahia H, Ashman JN, Cawkwell L et al. Karyotypic variation between independently cultured strains of the cell line MCF-7 identified by multicolour fluorescence in situ hybridization. Int J Oncol 2002 20 : 489 494.
    • (2002) Int J Oncol , vol.20 , pp. 489-494
    • Bahia, H.1    Ashman, J.N.2    Cawkwell, L.3
  • 26
    • 28544450783 scopus 로고    scopus 로고
    • The biochemical and morphological alterations following administration of melatonin, retinoic acid and Nigella sativa in mammary carcinoma: An animal model
    • Abd El-Aziz MA, Hassan HA, Mohamed MH et al. The biochemical and morphological alterations following administration of melatonin, retinoic acid and Nigella sativa in mammary carcinoma: an animal model. Int J Exp Path 2005 86 : 383 396.
    • (2005) Int J Exp Path , vol.86 , pp. 383-396
    • Abd El-Aziz, M.A.1    Hassan, H.A.2    Mohamed, M.H.3
  • 27
    • 2442621492 scopus 로고    scopus 로고
    • Role of AIF in caspase-dependent and caspase-independent cell death
    • Cregan SP, Dawson VL, Slack RS. Role of AIF in caspase-dependent and caspase-independent cell death. Oncogene 2004 23 : 2785 2796.
    • (2004) Oncogene , vol.23 , pp. 2785-2796
    • Cregan, S.P.1    Dawson, V.L.2    Slack, R.S.3
  • 28
    • 0037037328 scopus 로고    scopus 로고
    • Apoptotic mechanisms in T47D and MCF-7 human breast cancer cells
    • Mooney LM, Al-Sakkaf KA, Brown BL, Dobson PR. Apoptotic mechanisms in T47D and MCF-7 human breast cancer cells. Br J Cancer 2002 87 : 909 917.
    • (2002) Br J Cancer , vol.87 , pp. 909-917
    • Mooney, L.M.1    Al-Sakkaf, K.A.2    Brown, B.L.3    Dobson, P.R.4
  • 29
    • 33847230852 scopus 로고    scopus 로고
    • The p53 family in differentiation and tumorigenesis
    • Siewe T. The p53 family in differentiation and tumorigenesis. Nat Rev Cancer 2007 7 : 165 168.
    • (2007) Nat Rev Cancer , vol.7 , pp. 165-168
    • Siewe, T.1
  • 30
    • 0033959744 scopus 로고    scopus 로고
    • MDM2-master regulator of the p53 tumor suppressor protein
    • Momand J, Wu HH, Dasgupta G. MDM2-master regulator of the p53 tumor suppressor protein. Gene 2000 242 : 15 29.
    • (2000) Gene , vol.242 , pp. 15-29
    • Momand, J.1    Wu, H.H.2    Dasgupta, G.3
  • 31
    • 0034704923 scopus 로고    scopus 로고
    • The loss of MDM2 induces p53-mediated apoptosis
    • De Rozieres S, Maya R, Oren M, Lozano G. The loss of MDM2 induces p53-mediated apoptosis. Oncogene 2000 19 : 1691 1697.
    • (2000) Oncogene , vol.19 , pp. 1691-1697
    • De Rozieres, S.1    Maya, R.2    Oren, M.3    Lozano, G.4
  • 32
    • 0035895606 scopus 로고    scopus 로고
    • Downregulation of MDM2 stabilizes p53 by inhibiting p53 ubiquitination in response to specific alkylating agents
    • Inoue T, Geyer RK, Yu ZK, Maki CG. Downregulation of MDM2 stabilizes p53 by inhibiting p53 ubiquitination in response to specific alkylating agents. FEBS Lett 2001 490 : 196 201.
    • (2001) FEBS Lett , vol.490 , pp. 196-201
    • Inoue, T.1    Geyer, R.K.2    Yu, Z.K.3    Maki, C.G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.