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Volumn 7, Issue , 2014, Pages 395-

The p53/microRNA connection in gastrointestinal cancer

Author keywords

Cancer; Gastrointestinal tract; MicroRNA; p53

Indexed keywords

MICRORNA; MICRORNA 107; MICRORNA 145; MICRORNA 15A; MICRORNA 16 I; MICRORNA 192; MICRORNA 194; MICRORNA 200; MICRORNA 215; MICRORNA 34A; MICRORNA 34B; MICRORNA 34C; PROTEIN P53; UNCLASSIFIED DRUG;

EID: 84907708301     PISSN: None     EISSN: 11787023     Source Type: Journal    
DOI: 10.2147/CEG.S43738     Document Type: Review
Times cited : (48)

References (255)
  • 1
    • 84907705077 scopus 로고    scopus 로고
    • International Agency for Research on Cancer. GLOBOCAN 2012: Estimated Cancer Incidence, Mortality and Prevalence Worldwide in 2012. Geneva: World Health Organization; 2014. Available from, Accessed July 30
    • International Agency for Research on Cancer. GLOBOCAN 2012: Estimated Cancer Incidence, Mortality and Prevalence Worldwide in 2012. Geneva: World Health Organization; 2014. Available from: http://globocan.iarc.fr/Pages/fact_sheets_population.aspx. Accessed July 30, 2014.
    • (2014)
  • 2
    • 84907689572 scopus 로고    scopus 로고
    • International Agency for Research on Cancer. IARC TP53 Databse. Geneva: World Health Organization, Available from, Accessed July 30, 2014
    • International Agency for Research on Cancer. IARC TP53 Databse. Geneva: World Health Organization; 2014. Available from: http://p53.iarc.fr/TP53SomaticMutations.aspx. Accessed July 30, 2014.
    • (2014)
  • 3
    • 0034676455 scopus 로고    scopus 로고
    • Surfing the p53 network
    • Vogelstein B, Lane D, Levine AJ. Surfing the p53 network. Nature. 2000;408(6810):307-310.
    • (2000) Nature , vol.408 , Issue.6810 , pp. 307-310
    • Vogelstein, B.1    Lane, D.2    Levine, A.J.3
  • 4
    • 0038075338 scopus 로고    scopus 로고
    • Decision making by p53: Life, death and cancer
    • Oren M. Decision making by p53: life, death and cancer. Cell Death Differ. 2003;10(4):431-442.
    • (2003) Cell Death Differ , vol.10 , Issue.4 , pp. 431-442
    • Oren, M.1
  • 5
    • 78650015522 scopus 로고    scopus 로고
    • The role of mutant p53 in human cancer
    • Goh AM, Coffill CR, Lane DP. The role of mutant p53 in human cancer. J Pathol. 2011;223(2):116-126.
    • (2011) J Pathol , vol.223 , Issue.2 , pp. 116-126
    • Goh, A.M.1    Coffill, C.R.2    Lane, D.P.3
  • 6
    • 78650316134 scopus 로고    scopus 로고
    • p53 Research: The past thirty years and the next thirty years
    • Lane D, Levine A. p53 Research: the past thirty years and the next thirty years. Cold Spring Harb Perspect Biol. 2010;2(12):a000893.
    • (2010) Cold Spring Harb Perspect Biol , vol.2 , Issue.12
    • Lane, D.1    Levine, A.2
  • 8
    • 35748961986 scopus 로고    scopus 로고
    • p53 enters the microRNA world
    • Hermeking H. p53 enters the microRNA world. Cancer Cell. 2007; 12(5):414-418.
    • (2007) Cancer Cell , vol.12 , Issue.5 , pp. 414-418
    • Hermeking, H.1
  • 9
    • 84866423871 scopus 로고    scopus 로고
    • MicroRNAs in the p53 network: Micromanagement of tumour suppression
    • Hermeking H. MicroRNAs in the p53 network: micromanagement of tumour suppression. Nat Rev Cancer. 2012;12(9):613-626.
    • (2012) Nat Rev Cancer , vol.12 , Issue.9 , pp. 613-626
    • Hermeking, H.1
  • 10
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell. 2004;116(2):281-297.
    • (2004) Cell , vol.116 , Issue.2 , pp. 281-297
    • Bartel, D.P.1
  • 11
    • 77955902024 scopus 로고    scopus 로고
    • The widespread regulation of microRNA biogenesis, function and decay
    • Krol J, Loedige I, Filipowicz W. The widespread regulation of microRNA biogenesis, function and decay. Nat Rev Genet. 2010;11(9):597-610.
    • (2010) Nat Rev Genet , vol.11 , Issue.9 , pp. 597-610
    • Krol, J.1    Loedige, I.2    Filipowicz, W.3
  • 12
    • 84876939170 scopus 로고    scopus 로고
    • The long and short of microRNA
    • Yates LA, Norbury CJ, Gilbert RJ. The long and short of microRNA. Cell. 2013;153(3):516-519.
    • (2013) Cell , vol.153 , Issue.3 , pp. 516-519
    • Yates, L.A.1    Norbury, C.J.2    Gilbert, R.J.3
  • 13
    • 60149095444 scopus 로고    scopus 로고
    • Most mammalian mRNAs are conserved targets of microRNAs
    • Friedman RC, Farh KK, Burge CB, Bartel DP. Most mammalian mRNAs are conserved targets of microRNAs. Genome Res. 2009;19(1): 92-105.
    • (2009) Genome Res , vol.19 , Issue.1 , pp. 92-105
    • Friedman, R.C.1    Farh, K.K.2    Burge, C.B.3    Bartel, D.P.4
  • 14
    • 84455173386 scopus 로고    scopus 로고
    • miRNAs in precancerous lesions of the gastrointestinal tract
    • Fassan M, Croce CM, Rugge M. miRNAs in precancerous lesions of the gastrointestinal tract. World J Gastroenterol. 2011;17(48): 5231-5239.
    • (2011) World J Gastroenterol , vol.17 , Issue.48 , pp. 5231-5239
    • Fassan, M.1    Croce, C.M.2    Rugge, M.3
  • 15
    • 79952113135 scopus 로고    scopus 로고
    • Impact of miRNAs in gastrointestinal cancer diagnosis and prognosis
    • Song B, Ju J. Impact of miRNAs in gastrointestinal cancer diagnosis and prognosis. Expert Rev Mol Med. 2010;12:e33.
    • (2010) Expert Rev Mol Med , vol.12
    • Song, B.1    Ju, J.2
  • 17
    • 84894614699 scopus 로고    scopus 로고
    • Clinical application of microRNA testing in neuroendocrine tumors of the gastrointestinal tract
    • Vicentini C, Fassan M, D’Angelo E, et al. Clinical application of microRNA testing in neuroendocrine tumors of the gastrointestinal tract. Molecules. 2014;19(2):2458-2468.
    • (2014) Molecules , vol.19 , Issue.2 , pp. 2458-2468
    • Vicentini, C.1    Fassan, M.2    D’angelo, E.3
  • 18
    • 84907689638 scopus 로고    scopus 로고
    • MicroRNAs (miRNA) as Biomarker(s) for Prognosis and Diagnosis of Gastrointestinal (GI) Cancers
    • Epub January 28
    • Macha MA, Seshacharyulu P, Krishn SR, et al. MicroRNAs (miRNA) as Biomarker(s) for Prognosis and Diagnosis of Gastrointestinal (GI) Cancers. Curr Pharm Des. Epub January 28, 2014.
    • (2014) Curr Pharm Des
    • Macha, M.A.1    Seshacharyulu, P.2    Krishn, S.R.3
  • 19
    • 84858973697 scopus 로고    scopus 로고
    • Circulating microRNAs as biomarkers, therapeutic targets, and signaling molecules
    • Ajit SK. Circulating microRNAs as biomarkers, therapeutic targets, and signaling molecules. Sensors (Basel). 2012;12(3):3359-3369.
    • (2012) Sensors (Basel) , vol.12 , Issue.3 , pp. 3359-3369
    • Ajit, S.K.1
  • 21
    • 34547458550 scopus 로고    scopus 로고
    • p53-mediated activation of miRNA34 candidate tumor-suppressor genes
    • Bommer GT, Gerin I, Feng Y, et al. p53-mediated activation of miRNA34 candidate tumor-suppressor genes. Curr Biol. 2007;17(15): 1298-1307.
    • (2007) Curr Biol , vol.17 , Issue.15 , pp. 1298-1307
    • Bommer, G.T.1    Gerin, I.2    Feng, Y.3
  • 22
    • 34249817549 scopus 로고    scopus 로고
    • Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis
    • Chang TC, Wentzel EA, Kent OA, et al. Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis. Mol Cell. 2007;26(5):745-752.
    • (2007) Mol Cell , vol.26 , Issue.5 , pp. 745-752
    • Chang, T.C.1    Wentzel, E.A.2    Kent, O.A.3
  • 23
    • 34548803950 scopus 로고    scopus 로고
    • MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth
    • Corney DC, Flesken-Nikitin A, Godwin AK, Wang W, Nikitin AY. MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth. Cancer Res. 2007;67(18):8433-8438.
    • (2007) Cancer Res , vol.67 , Issue.18 , pp. 8433-8438
    • Corney, D.C.1    Flesken-Nikitin, A.2    Godwin, A.K.3    Wang, W.4    Nikitin, A.Y.5
  • 24
    • 34250851115 scopus 로고    scopus 로고
    • A microRNA component of the p53 tumour suppressor network
    • He L, He X, Lim LP, et al. A microRNA component of the p53 tumour suppressor network. Nature. 2007;447(7148):1130-1134.
    • (2007) Nature , vol.447 , Issue.7148 , pp. 1130-1134
    • He, L.1    He, X.2    Lim, L.P.3
  • 25
    • 34249822779 scopus 로고    scopus 로고
    • Transcriptional activation of miR-34a contributes to p53-mediated apoptosis
    • Raver-Shapira N, Marciano E, Meiri E, et al. Transcriptional activation of miR-34a contributes to p53-mediated apoptosis. Mol Cell. 2007;26(5):731-743.
    • (2007) Mol Cell , vol.26 , Issue.5 , pp. 731-743
    • Raver-Shapira, N.1    Marciano, E.2    Meiri, E.3
  • 26
    • 34250868124 scopus 로고    scopus 로고
    • Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: MiR-34a is a p53 target that induces apoptosis and G1-arrest
    • Tarasov V, Jung P, Verdoodt B, et al. Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest. Cell Cycle. 2007;6(13):1586-1593.
    • (2007) Cell Cycle , vol.6 , Issue.13 , pp. 1586-1593
    • Tarasov, V.1    Jung, P.2    Verdoodt, B.3
  • 27
    • 34848868157 scopus 로고    scopus 로고
    • Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells
    • Tazawa H, Tsuchiya N, Izumiya M, Nakagama H. Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells. Proc Natl Acad Sci U S A. 2007;104(39):15472-15477.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , Issue.39 , pp. 15472-15477
    • Tazawa, H.1    Tsuchiya, N.2    Izumiya, M.3    Nakagama, H.4
  • 29
    • 46249107572 scopus 로고    scopus 로고
    • Loss of miRNA biogenesis induces p19Arf-p53 signaling and senescence in primary cells
    • Mudhasani R, Zhu Z, Hutvagner G, et al. Loss of miRNA biogenesis induces p19Arf-p53 signaling and senescence in primary cells. J Cell Biol. 2008;181(7):1055-1063.
    • (2008) J Cell Biol , vol.181 , Issue.7 , pp. 1055-1063
    • Mudhasani, R.1    Zhu, Z.2    Hutvagner, G.3
  • 30
    • 77958558613 scopus 로고    scopus 로고
    • TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs
    • Su X, Chakravarti D, Cho MS, et al. TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs. Nature. 2010;467(7318):986-990.
    • (2010) Nature , vol.467 , Issue.7318 , pp. 986-990
    • Su, X.1    Chakravarti, D.2    Cho, M.S.3
  • 31
    • 80055057855 scopus 로고    scopus 로고
    • Selective inhibition of microRNA accessibility by RBM38 is required for p53 activity
    • Léveillé N, Elkon R, Davalos V, et al. Selective inhibition of microRNA accessibility by RBM38 is required for p53 activity. Nat Commun. 2011;2:513.
    • (2011) Nat Commun , vol.2 , pp. 513
    • Léveillé, N.1    Elkon, R.2    Davalos, V.3
  • 32
    • 79956143950 scopus 로고    scopus 로고
    • p53 regulates epithelial-mesenchymal transition through microRNAs targeting ZEB1 and ZEB2
    • Kim T, Veronese A, Pichiorri F, et al. p53 regulates epithelial-mesenchymal transition through microRNAs targeting ZEB1 and ZEB2. J Exp Med. 2011;208(5):875-883.
    • (2011) J Exp Med , vol.208 , Issue.5 , pp. 875-883
    • Kim, T.1    Veronese, A.2    Pichiorri, F.3
  • 33
    • 78650861867 scopus 로고    scopus 로고
    • Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia
    • Fabbri M, Bottoni A, Shimizu M, et al. Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia. JAMA. 2011;305(1):59-67.
    • (2011) JAMA , vol.305 , Issue.1 , pp. 59-67
    • Fabbri, M.1    Bottoni, A.2    Shimizu, M.3
  • 34
    • 57749099102 scopus 로고    scopus 로고
    • p53-Responsive micrornas 192 and 215 are capable of inducing cell cycle arrest
    • Braun CJ, Zhang X, Savelyeva I, et al. p53-Responsive micrornas 192 and 215 are capable of inducing cell cycle arrest. Cancer Res. 2008;68(24):10094-10104.
    • (2008) Cancer Res , vol.68 , Issue.24 , pp. 10094-10104
    • Braun, C.J.1    Zhang, X.2    Savelyeva, I.3
  • 35
    • 62549148270 scopus 로고    scopus 로고
    • p53 represses c-Myc through induction of the tumor suppressor miR-145
    • Sachdeva M, Zhu S, Wu F, et al. p53 represses c-Myc through induction of the tumor suppressor miR-145. Proc Natl Acad Sci U S A. 2009; 106(9):3207-3212.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.9 , pp. 3207-3212
    • Sachdeva, M.1    Zhu, S.2    Wu, F.3
  • 36
    • 79551478752 scopus 로고    scopus 로고
    • p53 activates the PANK1/miRNA-107 gene leading to downregulation of CDK6 and p130 cell cycle proteins
    • Böhlig L, Friedrich M, Engeland K. p53 activates the PANK1/miRNA-107 gene leading to downregulation of CDK6 and p130 cell cycle proteins. Nucleic Acids Res. 2011;39(2):440-453.
    • (2011) Nucleic Acids Res , vol.39 , Issue.2 , pp. 440-453
    • Böhlig, L.1    Friedrich, M.2    Engeland, K.3
  • 37
    • 84862843347 scopus 로고    scopus 로고
    • p53-facilitated miR-199a-3p regulates somatic cell reprogramming
    • Wang J, He Q, Han C, et al. p53-facilitated miR-199a-3p regulates somatic cell reprogramming. Stem Cells. 2012;30(7):1405-1413.
    • (2012) Stem Cells , vol.30 , Issue.7 , pp. 1405-1413
    • Wang, J.1    He, Q.2    Han, C.3
  • 38
    • 84866280242 scopus 로고    scopus 로고
    • Expression of miR-34 is lost in colon cancer which can be re-expressed by a novel agent CDF
    • Roy S, Levi E, Majumdar AP, Sarkar FH. Expression of miR-34 is lost in colon cancer which can be re-expressed by a novel agent CDF. J Hematol Oncol. 2012;5:58.
    • (2012) J Hematol Oncol , vol.5 , pp. 58
    • Roy, S.1    Levi, E.2    Majumdar, A.P.3    Sarkar, F.H.4
  • 39
    • 84896716496 scopus 로고    scopus 로고
    • Inactivation of miR-34a by aberrant CpG methylation in Kazakh patients with esophageal carcinoma
    • Cui X, Zhao Z, Liu D, et al. Inactivation of miR-34a by aberrant CpG methylation in Kazakh patients with esophageal carcinoma. J Exp Clin Cancer Res. 2014;33:20.
    • (2014) J Exp Clin Cancer Res , vol.33 , pp. 20
    • Cui, X.1    Zhao, Z.2    Liu, D.3
  • 40
    • 84883298319 scopus 로고    scopus 로고
    • Evaluation of MicroRNA expression pattern of gastric adenocarcinoma associated with socioeconomic, environmental and lifestyle factors in northwestern Hungary
    • Stánitz E, Juhász K, Tóth C, Gombos K, Natali PG, Ember I. Evaluation of MicroRNA expression pattern of gastric adenocarcinoma associated with socioeconomic, environmental and lifestyle factors in northwestern Hungary. Anticancer Res. 2013;33(8):3195-3200.
    • (2013) Anticancer Res , vol.33 , Issue.8 , pp. 3195-3200
    • Stánitz, E.1    Juhász, K.2    Tóth, C.3    Gombos, K.4    Natali, P.G.5    Ember, I.6
  • 41
    • 84899646114 scopus 로고    scopus 로고
    • Methylation-associated silencing of microRNA-34b in hepatocellular carcinoma cancer
    • Xie K, Liu J, Chen J, et al. Methylation-associated silencing of microRNA-34b in hepatocellular carcinoma cancer. Gene. 2014;543(1):101-107.
    • (2014) Gene , vol.543 , Issue.1 , pp. 101-107
    • Xie, K.1    Liu, J.2    Chen, J.3
  • 42
    • 84881319995 scopus 로고    scopus 로고
    • Functional role of miR-34 family in human cancer
    • Wang R, Ma J, Wu Q, et al. Functional role of miR-34 family in human cancer. Curr Drug Targets. 2013;14(10):1185-1191.
    • (2013) Curr Drug Targets , vol.14 , Issue.10 , pp. 1185-1191
    • Wang, R.1    Ma, J.2    Wu, Q.3
  • 43
    • 84901704452 scopus 로고    scopus 로고
    • The p53/miR-34 axis in development and disease
    • Rokavec M, Li H, Jiang L, Hermeking H. The p53/miR-34 axis in development and disease. J Mol Cell Biol. 2014;6(3):214-230.
    • (2014) J Mol Cell Biol , vol.6 , Issue.3 , pp. 214-230
    • Rokavec, M.1    Li, H.2    Jiang, L.3    Hermeking, H.4
  • 44
    • 84864755975 scopus 로고    scopus 로고
    • MicroRNA-34a modulates MDM4 expression via a target site in the open reading frame
    • Mandke P, Wyatt N, Fraser J, Bates B, Berberich SJ, Markey MP. MicroRNA-34a modulates MDM4 expression via a target site in the open reading frame. PLoS One. 2012;7(8):e42034.
    • (2012) PLoS One , vol.7 , Issue.8
    • Mandke, P.1    Wyatt, N.2    Fraser, J.3    Bates, B.4    Berberich, S.J.5    Markey, M.P.6
  • 45
    • 84896897599 scopus 로고    scopus 로고
    • A positive feedback between p53 and miR-34 miRNAs mediates tumor suppression
    • Okada N, Lin CP, Ribeiro MC, et al. A positive feedback between p53 and miR-34 miRNAs mediates tumor suppression. Genes Dev. 2014;28(5):438-450.
    • (2014) Genes Dev , vol.28 , Issue.5 , pp. 438-450
    • Okada, N.1    Lin, C.P.2    Ribeiro, M.C.3
  • 47
    • 84888131014 scopus 로고    scopus 로고
    • Elevated microRNA-34a in obesity reduces NAD+ levels and SIRT1 activity by directly targeting NAMPT
    • Choi SE, Fu T, Seok S, et al. Elevated microRNA-34a in obesity reduces NAD+ levels and SIRT1 activity by directly targeting NAMPT. Aging Cell. 2013;12(6):1062-1072.
    • (2013) Aging Cell , vol.12 , Issue.6 , pp. 1062-1072
    • Choi, S.E.1    Fu, T.2    Seok, S.3
  • 48
    • 84856384698 scopus 로고    scopus 로고
    • The c-MYC oncoprotein, the NAMPT enzyme, the SIRT1-inhibitor DBC1, and the SIRT1 deacetylase form a positive feedback loop
    • Menssen A, Hydbring P, Kapelle K, et al. The c-MYC oncoprotein, the NAMPT enzyme, the SIRT1-inhibitor DBC1, and the SIRT1 deacetylase form a positive feedback loop. Proc Natl Acad Sci U S A. 2012;109(4):E187-E196.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , Issue.4 , pp. E187-E196
    • Menssen, A.1    Hydbring, P.2    Kapelle, K.3
  • 49
    • 79959837062 scopus 로고    scopus 로고
    • SIRT1 promotes N-Myc oncogenesis through a positive feedback loop involving the effects of MKP3 and ERK on N-Myc protein stability
    • Marshall GM, Liu PY, Gherardi S, et al. SIRT1 promotes N-Myc oncogenesis through a positive feedback loop involving the effects of MKP3 and ERK on N-Myc protein stability. PLoS Genet. 2011;7(6): e1002135.
    • (2011) PLoS Genet , vol.7 , Issue.6
    • Marshall, G.M.1    Liu, P.Y.2    Gherardi, S.3
  • 50
    • 84055184850 scopus 로고    scopus 로고
    • miR-34 and SNAIL form a double-negative feedback loop to regulate epithelial-mesenchymal transitions
    • Siemens H, Jackstadt R, Hünten S, et al. miR-34 and SNAIL form a double-negative feedback loop to regulate epithelial-mesenchymal transitions. Cell Cycle. 2011;10(24):4256-4271.
    • (2011) Cell Cycle , vol.10 , Issue.24 , pp. 4256-4271
    • Siemens, H.1    Jackstadt, R.2    Hünten, S.3
  • 51
    • 44649163918 scopus 로고    scopus 로고
    • A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells
    • Burk U, Schubert J, Wellner U, et al. A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells. EMBO Rep. 2008;9(6):582-589.
    • (2008) EMBO Rep , vol.9 , Issue.6 , pp. 582-589
    • Burk, U.1    Schubert, J.2    Wellner, U.3
  • 52
    • 43049103824 scopus 로고    scopus 로고
    • The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
    • Gregory PA, Bert AG, Paterson EL, et al. The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nat Cell Biol. 2008;10(5):593-601.
    • (2008) Nat Cell Biol , vol.10 , Issue.5 , pp. 593-601
    • Gregory, P.A.1    Bert, A.G.2    Paterson, E.L.3
  • 53
    • 84865973348 scopus 로고    scopus 로고
    • ZEB1 drives prometastatic actin cytoskeletal remodeling by downregulating miR-34a expression
    • Ahn YH, Gibbons DL, Chakravarti D, et al. ZEB1 drives prometastatic actin cytoskeletal remodeling by downregulating miR-34a expression. J Clin Invest. 2012;122(9):3170-3183.
    • (2012) J Clin Invest , vol.122 , Issue.9 , pp. 3170-3183
    • Ahn, Y.H.1    Gibbons, D.L.2    Chakravarti, D.3
  • 54
    • 84888875112 scopus 로고    scopus 로고
    • SNAIL and miR-34a feed-forward regulation of ZNF281/ZBP99 promotes epithelial-mesenchymal transition
    • Hahn S, Jackstadt R, Siemens H, Hünten S, Hermeking H. SNAIL and miR-34a feed-forward regulation of ZNF281/ZBP99 promotes epithelial-mesenchymal transition. EMBO J. 2013;32(23):3079-3095.
    • (2013) EMBO J , vol.32 , Issue.23 , pp. 3079-3095
    • Hahn, S.1    Jackstadt, R.2    Siemens, H.3    Hünten, S.4    Hermeking, H.5
  • 55
    • 84897561550 scopus 로고    scopus 로고
    • IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis
    • Rokavec M, Öner MG, Li H, et al. IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis. J Clin Invest. 2014;124(4):1853-1867.
    • (2014) J Clin Invest , vol.124 , Issue.4 , pp. 1853-1867
    • Rokavec, M.1    Öner, M.G.2    Li, H.3
  • 56
    • 84869219338 scopus 로고    scopus 로고
    • miR-34-a microRNA replacement therapy is headed to the clinic
    • Bader AG. miR-34-a microRNA replacement therapy is headed to the clinic. Front Genet. 2012;3:120.
    • (2012) Front Genet , vol.3 , pp. 120
    • Bader, A.G.1
  • 57
    • 80051590849 scopus 로고    scopus 로고
    • Restitution of tumor suppressor microRNAs using a systemic nanovector inhibits pancreatic cancer growth in mice
    • Pramanik D, Campbell NR, Karikari C, et al. Restitution of tumor suppressor microRNAs using a systemic nanovector inhibits pancreatic cancer growth in mice. Mol Cancer Ther. 2011;10(8):1470-1480.
    • (2011) Mol Cancer Ther , vol.10 , Issue.8 , pp. 1470-1480
    • Pramanik, D.1    Campbell, N.R.2    Karikari, C.3
  • 58
    • 84869083907 scopus 로고    scopus 로고
    • Systemic microRNA-34a delivery induces apoptosis and abrogates growth of diffuse large B-cell lymphoma in vivo
    • Craig VJ, Tzankov A, Flori M, Schmid CA, Bader AG, Müller A. Systemic microRNA-34a delivery induces apoptosis and abrogates growth of diffuse large B-cell lymphoma in vivo. Leukemia. 2012; 26(11):2421-2424.
    • (2012) Leukemia , vol.26 , Issue.11 , pp. 2421-2424
    • Craig, V.J.1    Tzankov, A.2    Flori, M.3    Schmid, C.A.4    Bader, A.G.5    Müller, A.6
  • 59
    • 77955022405 scopus 로고    scopus 로고
    • Development of a lung cancer therapeutic based on the tumor suppressor microRNA-34
    • Wiggins JF, Ruffino L, Kelnar K, et al. Development of a lung cancer therapeutic based on the tumor suppressor microRNA-34. Cancer Res. 2010;70(14):5923-5930.
    • (2010) Cancer Res , vol.70 , Issue.14 , pp. 5923-5930
    • Wiggins, J.F.1    Ruffino, L.2    Kelnar, K.3
  • 60
    • 84907696176 scopus 로고    scopus 로고
    • Mirna Therapeutics, Inc. [homepage on the Internet]. Austin: Mirna Therapeutics, Inc, Available from, Accessed April 30, 2014
    • Mirna Therapeutics, Inc. [homepage on the Internet]. Austin: Mirna Therapeutics, Inc.; 2014. Available from: http://www.mirnarx.com/. Accessed April 30, 2014.
    • (2014)
  • 61
    • 54449092239 scopus 로고    scopus 로고
    • Effects of miR-34a on cell growth and chemoresistance in prostate cancer PC3 cells
    • Fujita Y, Kojima K, Hamada N, et al. Effects of miR-34a on cell growth and chemoresistance in prostate cancer PC3 cells. Biochem Biophys Res Commun. 2008;377(1):114-119.
    • (2008) Biochem Biophys Res Commun , vol.377 , Issue.1 , pp. 114-119
    • Fujita, Y.1    Kojima, K.2    Hamada, N.3
  • 62
    • 84859163248 scopus 로고    scopus 로고
    • MiR-34a chemosensitizes bladder cancer cells to cisplatin treatment regardless of p53-Rb pathway status
    • Vinall RL, Ripoll AZ, Wang S, Pan C-X, deVere White RW. MiR-34a chemosensitizes bladder cancer cells to cisplatin treatment regardless of p53-Rb pathway status. Int J Cancer. 2012;130(11):2526-2538.
    • (2012) Int J Cancer , vol.130 , Issue.11 , pp. 2526-2538
    • Vinall, R.L.1    Ripoll, A.Z.2    Wang, S.3    Pan, C.-X.4    Devere White, R.W.5
  • 63
    • 53949090314 scopus 로고    scopus 로고
    • Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres
    • Ji Q, Hao X, Meng Y, et al. Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres. BMC Cancer. 2008;8:266.
    • (2008) BMC Cancer , vol.8 , pp. 266
    • Ji, Q.1    Hao, X.2    Meng, Y.3
  • 64
    • 69949087531 scopus 로고    scopus 로고
    • MicroRNA miR-34 inhibits human pancreatic cancer tumor-initiating cells
    • Ji Q, Hao X, Zhang M, et al. MicroRNA miR-34 inhibits human pancreatic cancer tumor-initiating cells. PLoS One. 2009;4(8):e6816.
    • (2009) PLoS One , vol.4 , Issue.8
    • Ji, Q.1    Hao, X.2    Zhang, M.3
  • 65
    • 84884679127 scopus 로고    scopus 로고
    • Repression of c-Kit by p53 is mediated by miR-34 and is associated with reduced chemoresistance, migration and stemness
    • Siemens H, Jackstadt R, Kaller M, Hermeking H. Repression of c-Kit by p53 is mediated by miR-34 and is associated with reduced chemoresistance, migration and stemness. Oncotarget. 2013;4(9): 1399-1415.
    • (2013) Oncotarget , vol.4 , Issue.9 , pp. 1399-1415
    • Siemens, H.1    Jackstadt, R.2    Kaller, M.3    Hermeking, H.4
  • 66
    • 49749126791 scopus 로고    scopus 로고
    • Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer
    • Lodygin D, Tarasov V, Epanchintsev A, et al. Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer. Cell Cycle. 2008;7(16):2591-2600.
    • (2008) Cell Cycle , vol.7 , Issue.16 , pp. 2591-2600
    • Lodygin, D.1    Tarasov, V.2    Epanchintsev, A.3
  • 67
    • 79954455860 scopus 로고    scopus 로고
    • Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas
    • Vogt M, Munding J, Grüner M, et al. Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas. Virchows Arch. 2011;458(3):313-322.
    • (2011) Virchows Arch , vol.458 , Issue.3 , pp. 313-322
    • Vogt, M.1    Munding, J.2    Grüner, M.3
  • 68
    • 49249121155 scopus 로고    scopus 로고
    • Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer
    • Toyota M, Suzuki H, Sasaki Y, et al. Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer. Cancer Res. 2008;68(11): 4123-4132.
    • (2008) Cancer Res , vol.68 , Issue.11 , pp. 4123-4132
    • Toyota, M.1    Suzuki, H.2    Sasaki, Y.3
  • 69
    • 78649787634 scopus 로고    scopus 로고
    • Methylation-associated silencing of microRNA-34b/c in gastric cancer and its involvement in an epigenetic field defect
    • Suzuki H, Yamamoto E, Nojima M, et al. Methylation-associated silencing of microRNA-34b/c in gastric cancer and its involvement in an epigenetic field defect. Carcinogenesis. 2010;31(12):2066-2073.
    • (2010) Carcinogenesis , vol.31 , Issue.12 , pp. 2066-2073
    • Suzuki, H.1    Yamamoto, E.2    Nojima, M.3
  • 70
    • 84873373140 scopus 로고    scopus 로고
    • Detection of miR-34a promoter methylation in combination with elevated expression of c-Met and β-catenin predicts distant metastasis of colon cancer
    • Siemens H, Neumann J, Jackstadt R, et al. Detection of miR-34a promoter methylation in combination with elevated expression of c-Met and β-catenin predicts distant metastasis of colon cancer. Clin Cancer Res. 2013;19(3):710-720.
    • (2013) Clin Cancer Res , vol.19 , Issue.3 , pp. 710-720
    • Siemens, H.1    Neumann, J.2    Jackstadt, R.3
  • 71
    • 74249123570 scopus 로고    scopus 로고
    • The miR-34 family in cancer and apoptosis
    • Hermeking H. The miR-34 family in cancer and apoptosis. Cell Death Differ. 2010;17(2):193-199.
    • (2010) Cell Death Differ , vol.17 , Issue.2 , pp. 193-199
    • Hermeking, H.1
  • 72
    • 84863050461 scopus 로고    scopus 로고
    • Epigenetic silencing of miR-34a in human prostate cancer cells and tumor tissue specimens can be reversed by BR-DIM treatment
    • Kong D, Heath E, Chen W, et al. Epigenetic silencing of miR-34a in human prostate cancer cells and tumor tissue specimens can be reversed by BR-DIM treatment. Am J Transl Res. 2012;4(1):14-23.
    • (2012) Am J Transl Res , vol.4 , Issue.1 , pp. 14-23
    • Kong, D.1    Heath, E.2    Chen, W.3
  • 73
    • 79952205258 scopus 로고    scopus 로고
    • Systematic analysis of microRNAs targeting the androgen receptor in prostate cancer cells
    • Östling P, Leivonen SK, Aakula A, et al. Systematic analysis of microRNAs targeting the androgen receptor in prostate cancer cells. Cancer Res. 2011;71(5):1956-1967.
    • (2011) Cancer Res , vol.71 , Issue.5 , pp. 1956-1967
    • Östling, P.1    Leivonen, S.K.2    Aakula, A.3
  • 74
    • 84894274025 scopus 로고    scopus 로고
    • Detection of miR-34a and miR-34b/c in stool sample as potential screening biomarkers for noninvasive diagnosis of colorectal cancer
    • Wu X., Song YC, Cao PL, et al. Detection of miR-34a and miR-34b/c in stool sample as potential screening biomarkers for noninvasive diagnosis of colorectal cancer. Med Oncol. 2014;31(4):894.
    • (2014) Med Oncol , vol.31 , Issue.4 , pp. 894
    • Wu, X.1    Song, Y.C.2    Cao, P.L.3
  • 75
    • 18744396337 scopus 로고    scopus 로고
    • Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
    • Calin GA, Dumitru CD, Shimizu M, et al. Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci U S A. 2002;99(24): 15524-15529.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , Issue.24 , pp. 15524-15529
    • Calin, G.A.1    Dumitru, C.D.2    Shimizu, M.3
  • 76
    • 73649116987 scopus 로고    scopus 로고
    • The DLEU2/miR-15a/16-1 cluster controls B cell proliferation and its deletion leads to chronic lymphocytic leukemia
    • Klein U, Lia M, Crespo M, et al. The DLEU2/miR-15a/16-1 cluster controls B cell proliferation and its deletion leads to chronic lymphocytic leukemia. Cancer Cell. 2010;17(1):28-40.
    • (2010) Cancer Cell , vol.17 , Issue.1 , pp. 28-40
    • Klein, U.1    Lia, M.2    Crespo, M.3
  • 77
    • 84890435747 scopus 로고    scopus 로고
    • Prognostic significance of microRNA-16 expression in human colorectal cancer
    • Qian J, Jiang B, Li M, Chen J, Fang M. Prognostic significance of microRNA-16 expression in human colorectal cancer. World J Surg. 2013;37(12):2944-2949.
    • (2013) World J Surg , vol.37 , Issue.12 , pp. 2944-2949
    • Qian, J.1    Jiang, B.2    Li, M.3    Chen, J.4    Fang, M.5
  • 79
    • 84874686245 scopus 로고    scopus 로고
    • microRNA-16 represses colorectal cancer cell growth in vitro by regulating the p53/survivin signaling pathway
    • Ma Q, Wang X, Li Z, et al. microRNA-16 represses colorectal cancer cell growth in vitro by regulating the p53/survivin signaling pathway. Oncol Rep. 2013;29(4):1652-1658.
    • (2013) Oncol Rep , vol.29 , Issue.4 , pp. 1652-1658
    • Ma, Q.1    Wang, X.2    Li, Z.3
  • 80
    • 84865085480 scopus 로고    scopus 로고
    • Vector-based miR-15a/16-1 plasmid inhibits colon cancer growth in vivo
    • Dai L, Wang W, Zhang S, et al. Vector-based miR-15a/16-1 plasmid inhibits colon cancer growth in vivo. Cell Biol Int. 2012;36(8): 765-770.
    • (2012) Cell Biol Int , vol.36 , Issue.8 , pp. 765-770
    • Dai, L.1    Wang, W.2    Zhang, S.3
  • 81
    • 79959702659 scopus 로고    scopus 로고
    • Hepatitis B virus X protein downregulates expression of the miR-16 family in malignant hepatocytes in vitro
    • Wu G, Yu F, Xiao Z, et al. Hepatitis B virus X protein downregulates expression of the miR-16 family in malignant hepatocytes in vitro. Br J Cancer. 2011;105(1):146-153.
    • (2011) Br J Cancer , vol.105 , Issue.1 , pp. 146-153
    • Wu, G.1    Yu, F.2    Xiao, Z.3
  • 82
    • 25444520537 scopus 로고    scopus 로고
    • miR-15 and miR-16 induce apoptosis by targeting BCL2
    • Cimmino A, Calin GA, Fabbri M, et al. miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc Natl Acad Sci U S A. 2005;102(39): 13944-13949.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , Issue.39 , pp. 13944-13949
    • Cimmino, A.1    Calin, G.A.2    Fabbri, M.3
  • 83
    • 52649088391 scopus 로고    scopus 로고
    • miR-16 family induces cell cycle arrest by regulating multiple cell cycle genes
    • Liu Q, Fu H, Sun F, et al. miR-16 family induces cell cycle arrest by regulating multiple cell cycle genes. Nucleic Acids Res. 2008;36(16): 5391-5404.
    • (2008) Nucleic Acids Res , vol.36 , Issue.16 , pp. 5391-5404
    • Liu, Q.1    Fu, H.2    Sun, F.3
  • 84
    • 55549114664 scopus 로고    scopus 로고
    • The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities
    • Bonci D, Coppola V, Musumeci M, et al. The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities. Nat Med. 2008;14(11):1271-1277.
    • (2008) Nat Med , vol.14 , Issue.11 , pp. 1271-1277
    • Bonci, D.1    Coppola, V.2    Musumeci, M.3
  • 85
    • 84892923276 scopus 로고    scopus 로고
    • p53-induced miR-15a/16-1 and AP4 form a double-negative feedback loop to regulate epithelial-mesenchymal transition and metastasis in colorectal cancer
    • Shi L, Jackstadt R, Siemens H, Li H, Kirchner T, Hermeking H. p53-induced miR-15a/16-1 and AP4 form a double-negative feedback loop to regulate epithelial-mesenchymal transition and metastasis in colorectal cancer. Cancer Res. 2014;74(2):532-542.
    • (2014) Cancer Res , vol.74 , Issue.2 , pp. 532-542
    • Shi, L.1    Jackstadt, R.2    Siemens, H.3    Li, H.4    Kirchner, T.5    Hermeking, H.6
  • 86
    • 84880682384 scopus 로고    scopus 로고
    • AP4 is a mediator of epithelial-mesenchymal transition and metastasis in colorectal cancer
    • Jackstadt R, Röh S, Neumann J, et al. AP4 is a mediator of epithelial-mesenchymal transition and metastasis in colorectal cancer. J Exp Med. 2013;210(7):1331-1350.
    • (2013) J Exp Med , vol.210 , Issue.7 , pp. 1331-1350
    • Jackstadt, R.1    Röh, S.2    Neumann, J.3
  • 87
    • 80052664208 scopus 로고    scopus 로고
    • Recent advances in p53 research and cancer treatment
    • Suzuki K, Matsubara H. Recent advances in p53 research and cancer treatment. J Biomed Biotechnol. 2011;2011:978312.
    • (2011) J Biomed Biotechnol , vol.2011 , pp. 978312
    • Suzuki, K.1    Matsubara, H.2
  • 88
    • 77956181723 scopus 로고    scopus 로고
    • miR-145, miR-133a and miR-133b: Tumor-suppressive miRNAs target FSCN1 in esophageal squamous cell carcinoma
    • Kano M, Seki N, Kikkawa N, et al. miR-145, miR-133a and miR-133b: Tumor-suppressive miRNAs target FSCN1 in esophageal squamous cell carcinoma. Int J Cancer. 2010;127(12):2804-2814.
    • (2010) Int J Cancer , vol.127 , Issue.12 , pp. 2804-2814
    • Kano, M.1    Seki, N.2    Kikkawa, N.3
  • 89
    • 84873057723 scopus 로고    scopus 로고
    • The molecular mechanism of microRNA-145 to suppress invasion-metastasis cascade in gastric cancer
    • Gao P, Xing A-Y, Zhou GY, et al. The molecular mechanism of microRNA-145 to suppress invasion-metastasis cascade in gastric cancer. Oncogene. 2013;32(4):491-501.
    • (2013) Oncogene , vol.32 , Issue.4 , pp. 491-501
    • Gao, P.1    Xing, A.-Y.2    Zhou, G.Y.3
  • 90
    • 84872093873 scopus 로고    scopus 로고
    • Expression of microRNAs in patients with pancreatic cancer and its prognostic significance
    • Papaconstantinou IG, Manta A, Gazouli M, et al. Expression of microRNAs in patients with pancreatic cancer and its prognostic significance. Pancreas. 2013;42(1):67-71.
    • (2013) Pancreas , vol.42 , Issue.1 , pp. 67-71
    • Papaconstantinou, I.G.1    Manta, A.2    Gazouli, M.3
  • 91
    • 39049128249 scopus 로고    scopus 로고
    • Altered expression of miR-21, miR-31, miR-143 and miR-145 is related to clinicopathologic features of colorectal cancer
    • Slaby O, Svoboda M, Fabian P, et al. Altered expression of miR-21, miR-31, miR-143 and miR-145 is related to clinicopathologic features of colorectal cancer. Oncology. 2007;72(5-6):397-402.
    • (2007) Oncology , vol.72 , Issue.5-6 , pp. 397-402
    • Slaby, O.1    Svoboda, M.2    Fabian, P.3
  • 92
    • 84882236274 scopus 로고    scopus 로고
    • Jung M, et al. miRNA profiling identifies candidate mirnas for bladder cancer diagnosis and clinical outcome
    • Ratert N, Meyer HA, Jung M, et al. miRNA profiling identifies candidate mirnas for bladder cancer diagnosis and clinical outcome. J Mol Diagn. 2013;15(5):695-705.
    • (2013) J Mol Diagn , vol.15 , Issue.5 , pp. 695-705
    • Ratert, N.1    Meyer, H.A.2
  • 93
    • 84885186640 scopus 로고    scopus 로고
    • Analysis of the combined action of miR-143 and miR-145 on oncogenic pathways in colorectal cancer cells reveals a coordinate program of gene repression
    • Pagliuca A, Valvo C, Fabrizi E, et al. Analysis of the combined action of miR-143 and miR-145 on oncogenic pathways in colorectal cancer cells reveals a coordinate program of gene repression. Oncogene. 2013;32(40):4806-4813.
    • (2013) Oncogene , vol.32 , Issue.40 , pp. 4806-4813
    • Pagliuca, A.1    Valvo, C.2    Fabrizi, E.3
  • 94
    • 79960963683 scopus 로고    scopus 로고
    • MicroRNA replacement therapy for miR-145 and miR-33a is efficacious in a model of colon carcinoma
    • Ibrahim AF, Weirauch U, Thomas M, Grünweller A, Hartmann RK, Aigner A. MicroRNA replacement therapy for miR-145 and miR-33a is efficacious in a model of colon carcinoma. Cancer Res. 2011;71(15): 5214-5224.
    • (2011) Cancer Res , vol.71 , Issue.15 , pp. 5214-5224
    • Ibrahim, A.F.1    Weirauch, U.2    Thomas, M.3    Grünweller, A.4    Hartmann, R.K.5    Aigner, A.6
  • 95
    • 84874609641 scopus 로고    scopus 로고
    • Wild-type p53 suppresses the epithelial-mesenchymal transition and stemness in PC-3 prostate cancer cells by modulating miR145
    • Ren D, Wang M, Guo W, et al. Wild-type p53 suppresses the epithelial-mesenchymal transition and stemness in PC-3 prostate cancer cells by modulating miR145. Int J Oncol. 2013;42(4):1473-1481.
    • (2013) Int J Oncol , vol.42 , Issue.4 , pp. 1473-1481
    • Ren, D.1    Wang, M.2    Guo, W.3
  • 96
    • 78650204499 scopus 로고    scopus 로고
    • Repression of the miR-143/145 cluster by oncogenic Ras initiates a tumor-promoting feed-forward pathway
    • Kent OA, Chivukula RR, Mullendore M, et al. Repression of the miR-143/145 cluster by oncogenic Ras initiates a tumor-promoting feed-forward pathway. Genes Dev. 2010;24(24):2754-2759.
    • (2010) Genes Dev , vol.24 , Issue.24 , pp. 2754-2759
    • Kent, O.A.1    Chivukula, R.R.2    Mullendore, M.3
  • 97
    • 67349149082 scopus 로고    scopus 로고
    • MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells
    • Xu N, Papagiannakopoulos T, Pan G, Thomson JA, Kosik KS. MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells. Cell. 2009;137(4): 647-658.
    • (2009) Cell , vol.137 , Issue.4 , pp. 647-658
    • Xu, N.1    Papagiannakopoulos, T.2    Pan, G.3    Thomson, J.A.4    Kosik, K.S.5
  • 98
    • 69349098834 scopus 로고    scopus 로고
    • Stem cells: The promises and perils of p53
    • Krizhanovsky V, Lowe SW. Stem cells: The promises and perils of p53. Nature. 2009;460(7259):1085-1086.
    • (2009) Nature , vol.460 , Issue.7259 , pp. 1085-1086
    • Krizhanovsky, V.1    Lowe, S.W.2
  • 99
    • 84871958603 scopus 로고    scopus 로고
    • Loss of microRNA-143/145 disturbs cellular growth and apoptosis of human epithelial cancers by impairing the MDM2-p53 feedback loop
    • Zhang J, Sun Q, Zhang Z, Ge S, Han ZG, Chen WT. Loss of microRNA-143/145 disturbs cellular growth and apoptosis of human epithelial cancers by impairing the MDM2-p53 feedback loop. Oncogene. 2013;32(1):61-69.
    • (2013) Oncogene , vol.32 , Issue.1 , pp. 61-69
    • Zhang, J.1    Sun, Q.2    Zhang, Z.3    Ge, S.4    Han, Z.G.5    Chen, W.T.6
  • 100
    • 77957936826 scopus 로고    scopus 로고
    • Downregulation of p53-inducible microRNAs 192, 194, and 215 Impairs the p53/MDM2 Autoregulatory Loop in Multiple Myeloma Development
    • Pichiorri F, Suh S-S, Rocci A, et al. Downregulation of p53-inducible microRNAs 192, 194, and 215 Impairs the p53/MDM2 Autoregulatory Loop in Multiple Myeloma Development. Cancer Cell. 2010;18(4):367-381.
    • (2010) Cancer Cell , vol.18 , Issue.4 , pp. 367-381
    • Pichiorri, F.1    Suh, S.-S.2    Rocci, A.3
  • 101
    • 84875358162 scopus 로고    scopus 로고
    • MicroRNA-215 inhibits relapse of colorectal cancer patients following radical surgery
    • Li S, Gao J, Gu J, Yuan J, Hua D, Shen L. MicroRNA-215 inhibits relapse of colorectal cancer patients following radical surgery. Med Oncol. 2013;30(2):549.
    • (2013) Med Oncol , vol.30 , Issue.2 , pp. 549
    • Li, S.1    Gao, J.2    Gu, J.3    Yuan, J.4    Hua, D.5    Shen, L.6
  • 102
    • 57749116172 scopus 로고    scopus 로고
    • Coordinated regulation of cell cycle transcripts by p53-Inducible microRNAs, miR-192 and miR-215
    • Georges SA, Biery MC, Kim SY, et al. Coordinated regulation of cell cycle transcripts by p53-Inducible microRNAs, miR-192 and miR-215. Cancer Res. 2008;68(24):10105-10112.
    • (2008) Cancer Res , vol.68 , Issue.24 , pp. 10105-10112
    • Georges, S.A.1    Biery, M.C.2    Kim, S.Y.3
  • 103
    • 84907686005 scopus 로고    scopus 로고
    • MicroRNA-192 suppresses liver metastasis of colon cancer. Oncogene
    • Geng L, Chaudhuri A, Talmon G, et al. MicroRNA-192 suppresses liver metastasis of colon cancer. Oncogene. Epub November 11, 2013.
    • (2013) Epub November , pp. 11
    • Geng, L.1    Chaudhuri, A.2    Talmon, G.3
  • 104
    • 80051793013 scopus 로고    scopus 로고
    • MicroRNA-194 inhibits epithelial to mesenchymal transition of endometrial cancer cells by targeting oncogene BMI-1
    • Dong P, Kaneuchi M, Watari H, et al. MicroRNA-194 inhibits epithelial to mesenchymal transition of endometrial cancer cells by targeting oncogene BMI-1. Mol Cancer. 2011;10:99.
    • (2011) Mol Cancer , vol.10 , pp. 99
    • Dong, P.1    Kaneuchi, M.2    Watari, H.3
  • 105
    • 73049110243 scopus 로고    scopus 로고
    • The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs
    • Wellner U, Schubert J, Burk UC, et al. The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs. Nat Cell Biol. 2009;11(12):1487-1495.
    • (2009) Nat Cell Biol , vol.11 , Issue.12 , pp. 1487-1495
    • Wellner, U.1    Schubert, J.2    Burk, U.C.3
  • 106
    • 68049114782 scopus 로고    scopus 로고
    • Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells
    • Shimono Y, Zabala M, Cho RW, et al. Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells. Cell. 2009;138(3):592-603.
    • (2009) Cell , vol.138 , Issue.3 , pp. 592-603
    • Shimono, Y.1    Zabala, M.2    Cho, R.W.3
  • 107
    • 84901018900 scopus 로고    scopus 로고
    • Regulation of colorectal carcinoma stemness, growth and metastasis by a miR-200c-Sox2 negative feedback loop mechanism
    • Lu YX, Yuan L, Xue XL, et al. Regulation of colorectal carcinoma stemness, growth and metastasis by a miR-200c-Sox2 negative feedback loop mechanism. Clin Cancer Res. 2014;20(10):2631-2642.
    • (2014) Clin Cancer Res , vol.20 , Issue.10 , pp. 2631-2642
    • Lu, Y.X.1    Yuan, L.2    Xue, X.L.3
  • 108
    • 84892806594 scopus 로고    scopus 로고
    • Circulating miR-200c levels significantly predict response to chemotherapy and prognosis of patients undergoing neoadjuvant chemotherapy for esophageal cancer
    • Tanaka K, Miyata H, Yamasaki M, et al. Circulating miR-200c levels significantly predict response to chemotherapy and prognosis of patients undergoing neoadjuvant chemotherapy for esophageal cancer. Ann Surg Oncol. 2013;20 Suppl 3:S607-S615.
    • (2013) Ann Surg Oncol , vol.20 , pp. S607-S615
    • Tanaka, K.1    Miyata, H.2    Yamasaki, M.3
  • 109
    • 84895923572 scopus 로고    scopus 로고
    • Serum miR-200c Is a Novel Prognostic and Metastasis-Predictive Biomarker in Patients With Colorectal Cancer
    • Toiyama Y, Hur K, Tanaka K, et al. Serum miR-200c Is a Novel Prognostic and Metastasis-Predictive Biomarker in Patients With Colorectal Cancer. Ann Surg. 2014;259(4):735-743.
    • (2014) Ann Surg , vol.259 , Issue.4 , pp. 735-743
    • Toiyama, Y.1    Hur, K.2    Tanaka, K.3
  • 110
    • 84868676544 scopus 로고    scopus 로고
    • Circulating miR-200c as a diagnostic and prognostic biomarker for gastric cancer
    • Valladares-Ayerbes M, Reboredo M, Medina-Villaamil V, et al. Circulating miR-200c as a diagnostic and prognostic biomarker for gastric cancer. J Transl Med. 2012;10:186.
    • (2012) J Transl Med , vol.10 , pp. 186
    • Valladares-Ayerbes, M.1    Reboredo, M.2    Medina-Villaamil, V.3
  • 111
    • 84889679431 scopus 로고    scopus 로고
    • Serum miR-200c and clinical outcome of patients with advanced esophageal squamous cancer receiving platinum-based chemotherapy
    • Yu H, Duan B, Jiang L, et al. Serum miR-200c and clinical outcome of patients with advanced esophageal squamous cancer receiving platinum-based chemotherapy. Am J Transl Res. 2013;6(1):71-77.
    • (2013) Am J Transl Res , vol.6 , Issue.1 , pp. 71-77
    • Yu, H.1    Duan, B.2    Jiang, L.3
  • 112
    • 84907708556 scopus 로고    scopus 로고
    • Plasma miR-200c and miR-18a as potential biomarkers for the detection of colorectal carcinoma
    • Zhang GJ, Zhou T, Liu ZL, Tian HP, Xia SS. Plasma miR-200c and miR-18a as potential biomarkers for the detection of colorectal carcinoma. Mol Clin Oncol. 2013;1(2):379-384.
    • (2013) Mol Clin Oncol , vol.1 , Issue.2 , pp. 379-384
    • Zhang, G.J.1    Zhou, T.2    Liu, Z.L.3    Tian, H.P.4    Xia, S.S.5
  • 113
    • 84870845421 scopus 로고    scopus 로고
    • Spatiotemporal regulation of epithelial-mesenchymal transition is essential for squamous cell carcinoma metastasis
    • Tsai JH, Donaher JL, Murphy DA, Chau S, Yang J. Spatiotemporal regulation of epithelial-mesenchymal transition is essential for squamous cell carcinoma metastasis. Cancer Cell. 2012;22(6):725-736.
    • (2012) Cancer Cell , vol.22 , Issue.6 , pp. 725-736
    • Tsai, J.H.1    Donaher, J.L.2    Murphy, D.A.3    Chau, S.4    Yang, J.5
  • 114
    • 77950905821 scopus 로고    scopus 로고
    • P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis
    • Yamakuchi M, Lotterman CD, Bao C, et al. P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis. Proc Natl Acad Sci U S A. 2010;107(14):6334-6339.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , Issue.14 , pp. 6334-6339
    • Yamakuchi, M.1    Lotterman, C.D.2    Bao, C.3
  • 115
    • 77953898940 scopus 로고    scopus 로고
    • A MicroRNA targeting dicer for metastasis control
    • Martello G, Rosato A, Ferrari F, et al. A MicroRNA targeting dicer for metastasis control. Cell. 2010;141(7):1195-1207.
    • (2010) Cell , vol.141 , Issue.7 , pp. 1195-1207
    • Martello, G.1    Rosato, A.2    Ferrari, F.3
  • 116
    • 80052384762 scopus 로고    scopus 로고
    • miR-107 promotes tumor progression by targeting the let-7 microRNA in mice and humans
    • Chen PS, Su JL, Cha ST, et al. miR-107 promotes tumor progression by targeting the let-7 microRNA in mice and humans. J Clin Invest. 2011;121(9):3442-3455.
    • (2011) J Clin Invest , vol.121 , Issue.9 , pp. 3442-3455
    • Chen, P.S.1    Su, J.L.2    Cha, S.T.3
  • 117
    • 84863891322 scopus 로고    scopus 로고
    • miR-103/107 promote metastasis of colorectal cancer by targeting the metastasis suppressors DAPK and KLF4
    • Chen HY, Lin YM, Chung HC, et al. miR-103/107 promote metastasis of colorectal cancer by targeting the metastasis suppressors DAPK and KLF4. Cancer Res. 2012;72(14):3631-3641.
    • (2012) Cancer Res , vol.72 , Issue.14 , pp. 3631-3641
    • Chen, H.Y.1    Lin, Y.M.2    Chung, H.C.3
  • 118
    • 80052178588 scopus 로고    scopus 로고
    • MicroRNA-107, an oncogene microRNA that regulates tumour invasion and metastasis by targeting DICER1 in gastric cancer
    • Li X, Zhang Y, Shi Y, et al. MicroRNA-107, an oncogene microRNA that regulates tumour invasion and metastasis by targeting DICER1 in gastric cancer. J Cell Mol Med. 2011;15(9):1887-1895.
    • (2011) J Cell Mol Med , vol.15 , Issue.9 , pp. 1887-1895
    • Li, X.1    Zhang, Y.2    Shi, Y.3
  • 119
    • 84860746857 scopus 로고    scopus 로고
    • Clinicopathological and prognostic significance of microRNA-107 and its relationship to DICER1 mRNA expression in gastric cancer
    • Inoue T, Iinuma H, Ogawa E, Inaba T, Fukushima R. Clinicopathological and prognostic significance of microRNA-107 and its relationship to DICER1 mRNA expression in gastric cancer. Oncol Rep. 2012;27(6): 1759-1764.
    • (2012) Oncol Rep , vol.27 , Issue.6 , pp. 1759-1764
    • Inoue, T.1    Iinuma, H.2    Ogawa, E.3    Inaba, T.4    Fukushima, R.5
  • 120
    • 84865423112 scopus 로고    scopus 로고
    • miR-107 targets cyclin-dependent kinase 6 expression, induces cell cycle G1 arrest and inhibits invasion in gastric cancer cells
    • Feng L, Xie Y, Zhang H, Wu Y. miR-107 targets cyclin-dependent kinase 6 expression, induces cell cycle G1 arrest and inhibits invasion in gastric cancer cells. Med Oncol. 2012;29(2):856-863.
    • (2012) Med Oncol , vol.29 , Issue.2 , pp. 856-863
    • Feng, L.1    Xie, Y.2    Zhang, H.3    Wu, Y.4
  • 121
    • 34247593034 scopus 로고    scopus 로고
    • Impaired microRNA processing enhances cellular transformation and tumorigenesis
    • Kumar MS, Lu J, Mercer KL, Golub TR, Jacks T. Impaired microRNA processing enhances cellular transformation and tumorigenesis. Nat Genet. 2007;39(5):673-677.
    • (2007) Nat Genet , vol.39 , Issue.5 , pp. 673-677
    • Kumar, M.S.1    Lu, J.2    Mercer, K.L.3    Golub, T.R.4    Jacks, T.5
  • 122
    • 84896707001 scopus 로고    scopus 로고
    • Upregulation of MicroRNA-107 induces proliferation in human gastric cancer cells by targeting the transcription factor FOXO1
    • Li F, Liu B, Gao Y, et al. Upregulation of MicroRNA-107 induces proliferation in human gastric cancer cells by targeting the transcription factor FOXO1. FEBS Lett. 2014;588(4):538-544.
    • (2014) FEBS Lett , vol.588 , Issue.4 , pp. 538-544
    • Li, F.1    Liu, B.2    Gao, Y.3
  • 123
    • 84878704825 scopus 로고    scopus 로고
    • MicroRNA-107 inhibits U87 glioma stem cells growth and invasion
    • Chen L, Chen XR, Chen FF, et al. MicroRNA-107 inhibits U87 glioma stem cells growth and invasion. Cell Mol Neurobiol. 2013;33(5): 651-657.
    • (2013) Cell Mol Neurobiol , vol.33 , Issue.5 , pp. 651-657
    • Chen, L.1    Chen, X.R.2    Chen, F.F.3
  • 124
    • 84876363054 scopus 로고    scopus 로고
    • Transcriptional cooperation between p53 and NF-κB p65 regulates microRNA-224 transcription in mouse ovarian granulosa cells
    • Liang M, Yao G, Yin M, et al. Transcriptional cooperation between p53 and NF-κB p65 regulates microRNA-224 transcription in mouse ovarian granulosa cells. Mol Cell Endocrinol. 2013;370(1-2):119-129.
    • (2013) Mol Cell Endocrinol , vol.370 , Issue.1-2 , pp. 119-129
    • Liang, M.1    Yao, G.2    Yin, M.3
  • 125
    • 84884211455 scopus 로고    scopus 로고
    • Inhibition of autophagy and tumor growth in colon cancer by miR-502
    • Zhai H, Song B, Xu X, Zhu W, Ju J. Inhibition of autophagy and tumor growth in colon cancer by miR-502. Oncogene. 2013;32(12): 1570-1579.
    • (2013) Oncogene , vol.32 , Issue.12 , pp. 1570-1579
    • Zhai, H.1    Song, B.2    Xu, X.3    Zhu, W.4    Ju, J.5
  • 126
    • 70349220767 scopus 로고    scopus 로고
    • Repression of the miR-17-92 cluster by p53 has an important function in hypoxia-induced apoptosis
    • Yan HL, Xue G, Mei Q, et al. Repression of the miR-17-92 cluster by p53 has an important function in hypoxia-induced apoptosis. EMBO J. 2009;28(18):2719-2732.
    • (2009) EMBO J , vol.28 , Issue.18 , pp. 2719-2732
    • Yan, H.L.1    Xue, G.2    Mei, Q.3
  • 127
    • 81855194117 scopus 로고    scopus 로고
    • miR-92 is a key oncogenic component of the miR-17-92 cluster in colon cancer
    • Tsuchida A, Ohno S, Wu W, et al. miR-92 is a key oncogenic component of the miR-17-92 cluster in colon cancer. Cancer Sci. 2011;102(12):2264-2271.
    • (2011) Cancer Sci , vol.102 , Issue.12 , pp. 2264-2271
    • Tsuchida, A.1    Ohno, S.2    Wu, W.3
  • 128
    • 77954382780 scopus 로고    scopus 로고
    • mir-17-92, a cluster of miRNAs in the midst of the cancer network
    • Olive V, Jiang I, He L. mir-17-92, a cluster of miRNAs in the midst of the cancer network. Int J Biochem Cell Biol. 2010;42(8):1348-1354.
    • (2010) Int J Biochem Cell Biol , vol.42 , Issue.8 , pp. 1348-1354
    • Olive, V.1    Jiang, I.2    He, L.3
  • 129
    • 64349101658 scopus 로고    scopus 로고
    • MicroRNA-125b is a novel negative regulator of p53
    • Le MT, Teh C, Shyh-Chang N, et al. MicroRNA-125b is a novel negative regulator of p53. Genes Dev. 2009;23(7):862-876.
    • (2009) Genes Dev , vol.23 , Issue.7 , pp. 862-876
    • Le, M.T.1    Teh, C.2    Shyh-Chang, N.3
  • 130
    • 80053437994 scopus 로고    scopus 로고
    • Conserved regulation of p53 network dosage by microRNA-125b occurs through evolving miRNA-target gene pairs
    • Le MT, Shyh-Chang N, Khaw SL, et al. Conserved regulation of p53 network dosage by microRNA-125b occurs through evolving miRNA-target gene pairs. PLoS Genet. 2011;7(9):e1002242.
    • (2011) PLoS Genet , vol.7 , Issue.9
    • Le, M.T.1    Shyh-Chang, N.2    Khaw, S.L.3
  • 131
    • 84903391546 scopus 로고    scopus 로고
    • Profiles of serum microRNAs; miR-125b-5p and miR223-3p serve as novel biomarkers for HBV-positive hepatocellular carcinoma
    • Giray BG, Emekdas G, Tezcan S, et al. Profiles of serum microRNAs; miR-125b-5p and miR223-3p serve as novel biomarkers for HBV-positive hepatocellular carcinoma. Mol Biol Rep. 2014;41(7): 4513-4519.
    • (2014) Mol Biol Rep , vol.41 , Issue.7 , pp. 4513-4519
    • Giray, B.G.1    Emekdas, G.2    Tezcan, S.3
  • 132
    • 79955039593 scopus 로고    scopus 로고
    • MicroRNA miR-125b is a prognostic marker in human colorectal cancer
    • Nishida N, Yokobori T, Mimori K, et al. MicroRNA miR-125b is a prognostic marker in human colorectal cancer. Int J Oncol. 2011;38(5): 1437-1443.
    • (2011) Int J Oncol , vol.38 , Issue.5 , pp. 1437-1443
    • Nishida, N.1    Yokobori, T.2    Mimori, K.3
  • 133
    • 77953096272 scopus 로고    scopus 로고
    • Negative regulation of tumor suppressor p53 by microRNA miR-504
    • Hu W, Chan CS, Wu R, et al. Negative regulation of tumor suppressor p53 by microRNA miR-504. Mol Cell. 2010;38(5):689-699.
    • (2010) Mol Cell , vol.38 , Issue.5 , pp. 689-699
    • Hu, W.1    Chan, C.S.2    Wu, R.3
  • 134
    • 79951812882 scopus 로고    scopus 로고
    • Negative regulation of the tumor suppressor p53 gene by microRNAs
    • Kumar M, Lu Z, Takwi AA, et al. Negative regulation of the tumor suppressor p53 gene by microRNAs. Oncogene. 2011;30(7): 843-853.
    • (2011) Oncogene , vol.30 , Issue.7 , pp. 843-853
    • Kumar, M.1    Lu, Z.2    Takwi, A.A.3
  • 135
    • 77955736174 scopus 로고    scopus 로고
    • miR-33-mediated downregulation of p53 controls hematopoietic stem cell self-renewal
    • Herrera-Merchan A, Cerrato C, Luengo G, et al. miR-33-mediated downregulation of p53 controls hematopoietic stem cell self-renewal. Cell Cycle. 2010;9(16):3277-3285.
    • (2010) Cell Cycle , vol.9 , Issue.16 , pp. 3277-3285
    • Herrera-Merchan, A.1    Cerrato, C.2    Luengo, G.3
  • 136
    • 77957764089 scopus 로고    scopus 로고
    • miR-380-5p represses p53 to control cellular survival and is associated with poor outcome in MYCN-amplified neuroblastoma
    • Swarbrick A, Woods SL, Shaw A, et al. miR-380-5p represses p53 to control cellular survival and is associated with poor outcome in MYCN-amplified neuroblastoma. Nat Med. 2010;16(10):1134-1140.
    • (2010) Nat Med , vol.16 , Issue.10 , pp. 1134-1140
    • Swarbrick, A.1    Woods, S.L.2    Shaw, A.3
  • 137
    • 84861222679 scopus 로고    scopus 로고
    • MicroRNA-25 promotes cell migration and invasion in esophageal squamous cell carcinoma
    • Xu X, Chen Z, Zhao X, et al. MicroRNA-25 promotes cell migration and invasion in esophageal squamous cell carcinoma. Biochem Biophys Res Commun. 2012;421(4):640-645.
    • (2012) Biochem Biophys Res Commun , vol.421 , Issue.4 , pp. 640-645
    • Xu, X.1    Chen, Z.2    Zhao, X.3
  • 138
    • 84880700831 scopus 로고    scopus 로고
    • miR-150 promotes the proliferation of lung cancer cells by targeting P53
    • Zhang N, Wei X, Xu L. miR-150 promotes the proliferation of lung cancer cells by targeting P53. FEBS Lett. 2013;587(15):2346-2351.
    • (2013) FEBS Lett , vol.587 , Issue.15 , pp. 2346-2351
    • Zhang, N.1    Wei, X.2    Xu, L.3
  • 139
    • 84880946591 scopus 로고    scopus 로고
    • miR-375 targets the p53 gene to regulate cellular response to ionizing radiation and etoposide in gastric cancer cells
    • Liu Y, Xing R, Zhang X, et al. miR-375 targets the p53 gene to regulate cellular response to ionizing radiation and etoposide in gastric cancer cells. DNA Repair (Amst). 2013;12(9):741-750.
    • (2013) DNA Repair (Amst) , vol.12 , Issue.9 , pp. 741-750
    • Liu, Y.1    Xing, R.2    Zhang, X.3
  • 140
    • 77952875310 scopus 로고    scopus 로고
    • MicroRNA-1285 inhibits the expression of p53 by directly targeting its 3′ untranslated region
    • Tian S, Huang S, Wu S, Guo W, Li J, He X. MicroRNA-1285 inhibits the expression of p53 by directly targeting its 3′ untranslated region. Biochem Biophys Res Commun. 2010;396(2):435-439.
    • (2010) Biochem Biophys Res Commun , vol.396 , Issue.2 , pp. 435-439
    • Tian, S.1    Huang, S.2    Wu, S.3    Guo, W.4    Li, J.5    He, X.6
  • 141
    • 84867417506 scopus 로고    scopus 로고
    • MicroRNA miR-214 regulates ovarian cancer cell stemness by targeting p53/Nanog
    • Xu CX, Xu M, Tan L, et al. MicroRNA miR-214 regulates ovarian cancer cell stemness by targeting p53/Nanog. J Biol Chem. 2012;287(42): 34970-34978.
    • (2012) J Biol Chem , vol.287 , Issue.42 , pp. 34970-34978
    • Xu, C.X.1    Xu, M.2    Tan, L.3
  • 142
    • 72049115805 scopus 로고    scopus 로고
    • MicroRNA 125a and its regulation of the p53 tumor suppressor gene
    • Zhang Y, Gao JS, Tang X, et al. MicroRNA 125a and its regulation of the p53 tumor suppressor gene. FEBS Lett. 2009;583(22):3725-3730.
    • (2009) FEBS Lett , vol.583 , Issue.22 , pp. 3725-3730
    • Zhang, Y.1    Gao, J.S.2    Tang, X.3
  • 143
    • 80052660944 scopus 로고    scopus 로고
    • miR-98 regulates cisplatin-induced A549 cell death by inhibiting TP53 pathway
    • Zhang S, Zhang C, Li Y, Wang P, Yue Z, Xie S. miR-98 regulates cisplatin-induced A549 cell death by inhibiting TP53 pathway. Biomed Pharmacother. 2011;65(6):436-442.
    • (2011) Biomed Pharmacother , vol.65 , Issue.6 , pp. 436-442
    • Zhang, S.1    Zhang, C.2    Li, Y.3    Wang, P.4    Yue, Z.5    Xie, S.6
  • 144
    • 84878173440 scopus 로고    scopus 로고
    • miR-150, p53 protein and relevant miRNAs consist of a regulatory network in NSCLC tumorigenesis
    • Wang DT, Ma ZL, Li YL, et al. miR-150, p53 protein and relevant miRNAs consist of a regulatory network in NSCLC tumorigenesis. Oncol Rep. 2013;30(1):492-498.
    • (2013) Oncol Rep , vol.30 , Issue.1 , pp. 492-498
    • Wang, D.T.1    Ma, Z.L.2    Li, Y.L.3
  • 145
    • 84896034405 scopus 로고    scopus 로고
    • Clinical significance of serum miR-223, miR-25 and miR-375 in patients with esophageal squamous cell carcinoma
    • Wu C, Li M, Hu C, Duan H. Clinical significance of serum miR-223, miR-25 and miR-375 in patients with esophageal squamous cell carcinoma. Mol Biol Rep. 2014;41(3):1257-1266.
    • (2014) Mol Biol Rep , vol.41 , Issue.3 , pp. 1257-1266
    • Wu, C.1    Li, M.2    Hu, C.3    Duan, H.4
  • 146
    • 84888259658 scopus 로고    scopus 로고
    • The expression of miR-25 is increased in colorectal cancer and is associated with patient prognosis
    • Li X, Yang C, Wang X, Zhang J, Zhang R, Liu R. The expression of miR-25 is increased in colorectal cancer and is associated with patient prognosis. Med Oncol. 2014;31(1):781.
    • (2014) Med Oncol , vol.31 , Issue.1 , pp. 781
    • Li, X.1    Yang, C.2    Wang, X.3    Zhang, J.4    Zhang, R.5    Liu, R.6
  • 147
    • 84873718626 scopus 로고    scopus 로고
    • mir-30d Regulates multiple genes in the autophagy pathway and impairs autophagy process in human cancer cells
    • Yang X, Zhong X, Tanyi JL, et al. mir-30d Regulates multiple genes in the autophagy pathway and impairs autophagy process in human cancer cells. Biochem Biophys Res Commun. 2013;431(3): 617-622.
    • (2013) Biochem Biophys Res Commun , vol.431 , Issue.3 , pp. 617-622
    • Yang, X.1    Zhong, X.2    Tanyi, J.L.3
  • 148
    • 84855388977 scopus 로고    scopus 로고
    • A combined array-based comparative genomic hybridization and functional library screening approach identifies mir-30d as an oncomir in cancer
    • Li N, Kaur S, Greshock J, et al. A combined array-based comparative genomic hybridization and functional library screening approach identifies mir-30d as an oncomir in cancer. Cancer Res. 2012;72(1): 154-164.
    • (2012) Cancer Res , vol.72 , Issue.1 , pp. 154-164
    • Li, N.1    Kaur, S.2    Greshock, J.3
  • 149
    • 79957900395 scopus 로고    scopus 로고
    • Aging and chronic DNA damage response activate a regulatory pathway involving miR-29 and p53
    • Ugalde AP, Ramsay AJ, de la Rosa J, et al. Aging and chronic DNA damage response activate a regulatory pathway involving miR-29 and p53. EMBO J. 2011;30(11):2219-2232.
    • (2011) EMBO J , vol.30 , Issue.11 , pp. 2219-2232
    • Ugalde, A.P.1    Ramsay, A.J.2    De La Rosa, J.3
  • 150
    • 58149215802 scopus 로고    scopus 로고
    • miR-29 miRNAs activate p53 by targeting p85 alpha and CDC42
    • Park SY, Lee JH, Ha M, Nam JW, Kim VN. miR-29 miRNAs activate p53 by targeting p85 alpha and CDC42. Nat Struct Mol Biol. 2009;16(1):23-29.
    • (2009) Nat Struct Mol Biol , vol.16 , Issue.1 , pp. 23-29
    • Park, S.Y.1    Lee, J.H.2    Ha, M.3    Nam, J.W.4    Kim, V.N.5
  • 151
    • 84875381512 scopus 로고    scopus 로고
    • The role of miRNA-29 family in cancer
    • Wang Y, Zhang X, Li H, Yu J, Ren X. The role of miRNA-29 family in cancer. Eur J Cell Biol. 2013;92(3):123-128.
    • (2013) Eur J Cell Biol , vol.92 , Issue.3 , pp. 123-128
    • Wang, Y.1    Zhang, X.2    Li, H.3    Yu, J.4    Ren, X.5
  • 152
    • 84893398343 scopus 로고    scopus 로고
    • Characterization of microRNA-29 family expression and investigation of their mechanistic roles in gastric cancer
    • Gong J, Li J, Wang Y, et al. Characterization of microRNA-29 family expression and investigation of their mechanistic roles in gastric cancer. Carcinogenesis. 2014;35(2):497-506.
    • (2014) Carcinogenesis , vol.35 , Issue.2 , pp. 497-506
    • Gong, J.1    Li, J.2    Wang, Y.3
  • 153
    • 84871416444 scopus 로고    scopus 로고
    • MicroRNA-29a-5p is a novel predictor for early recurrence of hepatitis B virus-related hepatocellular carcinoma after surgical resection
    • Zhu H-T, Dong Q-Z, Sheng Y-Y, et al. MicroRNA-29a-5p is a novel predictor for early recurrence of hepatitis B virus-related hepatocellular carcinoma after surgical resection. PLoS One. 2012;7(12):e52393.
    • (2012) PLoS One , vol.7 , Issue.12
    • Zhu, H.-T.1    Dong, Q.-Z.2    Sheng, Y.-Y.3
  • 154
    • 77950602604 scopus 로고    scopus 로고
    • Effects of microRNA-29 on apoptosis, tumorigenicity, and prognosis of hepatocellular carcinoma
    • Xiong Y, Fang JH, Yun JP, et al. Effects of microRNA-29 on apoptosis, tumorigenicity, and prognosis of hepatocellular carcinoma. Hepatology. 2010;51(3):836-845.
    • (2010) Hepatology , vol.51 , Issue.3 , pp. 836-845
    • Xiong, Y.1    Fang, J.H.2    Yun, J.P.3
  • 155
    • 57149138434 scopus 로고    scopus 로고
    • MicroRNA involvement in hepatocellular carcinoma
    • Gramantieri L, Fornari F, Callegari E, et al. MicroRNA involvement in hepatocellular carcinoma. J Cell Mol Med. 2008;12(6A): 2189-2204.
    • (2008) J Cell Mol Med , vol.12 , Issue.6A , pp. 2189-2204
    • Gramantieri, L.1    Fornari, F.2    Callegari, E.3
  • 156
    • 67651007766 scopus 로고    scopus 로고
    • MiR-122/cyclin G1 interaction modulates p53 activity and affects doxorubicin sensitivity of human hepatocarcinoma cells
    • Fornari F, Gramantieri L, Giovannini C, et al. MiR-122/cyclin G1 interaction modulates p53 activity and affects doxorubicin sensitivity of human hepatocarcinoma cells. Cancer Res. 2009;69(14): 5761-5767.
    • (2009) Cancer Res , vol.69 , Issue.14 , pp. 5761-5767
    • Fornari, F.1    Gramantieri, L.2    Giovannini, C.3
  • 157
    • 0036235121 scopus 로고    scopus 로고
    • Cyclin G recruits PP2A to dephosphorylate Mdm2
    • Okamoto K, Li H, Jensen MR, et al. Cyclin G recruits PP2A to dephosphorylate Mdm2. Mol Cell. 2002;9(4):761-771.
    • (2002) Mol Cell , vol.9 , Issue.4 , pp. 761-771
    • Okamoto, K.1    Li, H.2    Jensen, M.R.3
  • 158
    • 0027944251 scopus 로고
    • Cyclin G is a transcriptional target of the p53 tumor suppressor protein
    • Okamoto K, Beach D. Cyclin G is a transcriptional target of the p53 tumor suppressor protein. EMBO J. 1994;13(20):4816-4822.
    • (1994) EMBO J , vol.13 , Issue.20 , pp. 4816-4822
    • Okamoto, K.1    Beach, D.2
  • 159
    • 84934437871 scopus 로고    scopus 로고
    • The p53/microRNA network in cancer: Experimental and bioinformatics approaches
    • Hünten S, Siemens H, Kaller M, Hermeking H. The p53/microRNA network in cancer: experimental and bioinformatics approaches. Adv Exp Med Biol. 2013;774:77-101.
    • (2013) Adv Exp Med Biol , vol.774 , pp. 77-101
    • Hünten, S.1    Siemens, H.2    Kaller, M.3    Hermeking, H.4
  • 160
    • 84864584473 scopus 로고    scopus 로고
    • Intact p53-dependent responses in miR-34-deficient mice
    • Concepcion CP, Han YC, Mu P, et al. Intact p53-dependent responses in miR-34-deficient mice. PLoS Genet. 2012;8(7):e1002797.
    • (2012) PLoS Genet , vol.8 , Issue.7
    • Concepcion, C.P.1    Han, Y.C.2    Mu, P.3
  • 161
    • 84906706945 scopus 로고    scopus 로고
    • Small RNA combination therapy for lung cancer
    • Xue W, Dahlman JE, Tammela T, et al. Small RNA combination therapy for lung cancer. Proc Natl Acad Sci USA. 2014;111(34):E3553-3561.
    • (2014) Proc Natl Acad Sci USA , vol.111 , Issue.34 , pp. E3553-E3561
    • Xue, W.1    Dahlman, J.E.2    Tammela, T.3
  • 162
    • 84869501780 scopus 로고    scopus 로고
    • Circulating miR-34a levels are reduced in colorectal cancer
    • Nugent M, Miller N, Kerin MJ. Circulating miR-34a levels are reduced in colorectal cancer. J Surg Oncol. 2012;106(8):947-952.
    • (2012) J Surg Oncol , vol.106 , Issue.8 , pp. 947-952
    • Nugent, M.1    Miller, N.2    Kerin, M.J.3
  • 163
    • 84863230238 scopus 로고    scopus 로고
    • MicroRNA-34a inhibits migration and invasion of colon cancer cells via targeting to Fra-1
    • Wu J, Wu G, Lv L, et al. MicroRNA-34a inhibits migration and invasion of colon cancer cells via targeting to Fra-1. Carcinogenesis. 2012;33(3):519-528.
    • (2012) Carcinogenesis , vol.33 , Issue.3 , pp. 519-528
    • Wu, J.1    Wu, G.2    Lv, L.3
  • 164
    • 84856336434 scopus 로고    scopus 로고
    • CpG island methylation status of miRNAs in esophageal squamous cell carcinoma
    • Chen X, Hu H, Guan X, et al. CpG island methylation status of miRNAs in esophageal squamous cell carcinoma. Int J Cancer. 2012;130(7):1607-1613.
    • (2012) Int J Cancer , vol.130 , Issue.7 , pp. 1607-1613
    • Chen, X.1    Hu, H.2    Guan, X.3
  • 165
    • 84855996930 scopus 로고    scopus 로고
    • MicroRNA molecular profiles associated with diagnosis, clinicopathologic criteria, and overall survival in patients with resectable pancreatic ductal adenocarcinoma
    • Jamieson NB, Morran DC, Morton JP, et al. MicroRNA molecular profiles associated with diagnosis, clinicopathologic criteria, and overall survival in patients with resectable pancreatic ductal adenocarcinoma. Clin Cancer Res. 2012;18(2):534-545.
    • (2012) Clin Cancer Res , vol.18 , Issue.2 , pp. 534-545
    • Jamieson, N.B.1    Morran, D.C.2    Morton, J.P.3
  • 166
    • 77954924558 scopus 로고    scopus 로고
    • MicroRNA-34b has an oncogenic role in esophageal squamous cell carcinoma
    • Harata K, Ishiguro H, Kuwabara Y, Kimura M, Mitsui A. MicroRNA-34b has an oncogenic role in esophageal squamous cell carcinoma. Oncol Lett. 2010;1(4):685-689.
    • (2010) Oncol Lett , vol.1 , Issue.4 , pp. 685-689
    • Harata, K.1    Ishiguro, H.2    Kuwabara, Y.3    Kimura, M.4    Mitsui, A.5
  • 167
    • 84875731982 scopus 로고    scopus 로고
    • Differential expression of miRNAs in esophageal cancer tissue
    • Liu SG, Qin XG, Zhao BS, et al. Differential expression of miRNAs in esophageal cancer tissue. Oncol Lett. 2013;5(5):1639-1642.
    • (2013) Oncol Lett , vol.5 , Issue.5 , pp. 1639-1642
    • Liu, S.G.1    Qin, X.G.2    Zhao, B.S.3
  • 168
    • 84899543082 scopus 로고    scopus 로고
    • Role of miR-200 family members in survival of colorectal cancer patients treated with fluoropyrimidines
    • Diaz T, Tejero R, Moreno I, et al. Role of miR-200 family members in survival of colorectal cancer patients treated with fluoropyrimidines. J Surg Oncol. 2014;109(7):676-683.
    • (2014) J Surg Oncol , vol.109 , Issue.7 , pp. 676-683
    • Diaz, T.1    Tejero, R.2    Moreno, I.3
  • 169
    • 84881551103 scopus 로고    scopus 로고
    • MicroRNA-200c modulates epithelial-to-mesenchymal transition (EMT) in human colorectal cancer metastasis
    • Hur K, Toiyama Y, Takahashi M, et al. MicroRNA-200c modulates epithelial-to-mesenchymal transition (EMT) in human colorectal cancer metastasis. Gut. 2013;62(9):1315-1326.
    • (2013) Gut , vol.62 , Issue.9 , pp. 1315-1326
    • Hur, K.1    Toiyama, Y.2    Takahashi, M.3
  • 170
    • 84888772543 scopus 로고    scopus 로고
    • Predicting distant metastasis and chemoresistance using plasma miRNAs
    • Chen J, Wang W, Zhang Y, Chen Y, Hu T. Predicting distant metastasis and chemoresistance using plasma miRNAs. Med Oncol. 2014; 31(1):799.
    • (2014) Med Oncol , vol.31 , Issue.1 , pp. 799
    • Chen, J.1    Wang, W.2    Zhang, Y.3    Chen, Y.4    Hu, T.5
  • 171
    • 84859911725 scopus 로고    scopus 로고
    • Dynamic epigenetic regulation of the microRNA-200 family mediates epithelial and mesenchymal transitions in human tumorigenesis
    • Davalos V, Moutinho C, Villanueva A, et al. Dynamic epigenetic regulation of the microRNA-200 family mediates epithelial and mesenchymal transitions in human tumorigenesis. Oncogene. 2012;31(16): 2062-2074.
    • (2012) Oncogene , vol.31 , Issue.16 , pp. 2062-2074
    • Davalos, V.1    Moutinho, C.2    Villanueva, A.3
  • 172
    • 67449083467 scopus 로고    scopus 로고
    • Down-regulation of miR-141 in gastric cancer and its involvement in cell growth
    • Du Y, Xu Y, Ding L, et al. Down-regulation of miR-141 in gastric cancer and its involvement in cell growth. J Gastroenterol. 2009;44(6): 556-561.
    • (2009) J Gastroenterol , vol.44 , Issue.6 , pp. 556-561
    • Du, Y.1    Xu, Y.2    Ding, L.3
  • 173
    • 84877263372 scopus 로고    scopus 로고
    • Expression of microRNAs, miR-21, miR-31, miR-122, miR-145, miR-146a, miR-200c, miR-221, miR-222, and miR-223 in patients with hepatocellular carcinoma or intrahepatic cholangiocarcinoma and its prognostic significance
    • Karakatsanis A, Papaconstantinou I, Gazouli M, Lyberopoulou A, Polymeneas G, Voros D. Expression of microRNAs, miR-21, miR-31, miR-122, miR-145, miR-146a, miR-200c, miR-221, miR-222, and miR-223 in patients with hepatocellular carcinoma or intrahepatic cholangiocarcinoma and its prognostic significance. Mol Carcinog. 2013;52(4):297-303.
    • (2013) Mol Carcinog , vol.52 , Issue.4 , pp. 297-303
    • Karakatsanis, A.1    Papaconstantinou, I.2    Gazouli, M.3    Lyberopoulou, A.4    Polymeneas, G.5    Voros, D.6
  • 174
    • 84892945531 scopus 로고    scopus 로고
    • Expression profile of microRNA-200 family in hepatocellular carcinoma with bile duct tumor thrombus
    • Yeh TS, Wang F, Chen TC, et al. Expression profile of microRNA-200 family in hepatocellular carcinoma with bile duct tumor thrombus. Ann Surg. 2014;259(2):346-354.
    • (2014) Ann Surg , vol.259 , Issue.2 , pp. 346-354
    • Yeh, T.S.1    Wang, F.2    Chen, T.C.3
  • 175
    • 84898878555 scopus 로고    scopus 로고
    • MiR-429 inhibits cells growth and invasion and regulates EMT-related marker genes by targeting Onecut2 in colorectal carcinoma
    • Sun Y, Shen S, Liu X, et al. MiR-429 inhibits cells growth and invasion and regulates EMT-related marker genes by targeting Onecut2 in colorectal carcinoma. Mol Cell Biochem. 2014;390(1-2):19-30.
    • (2014) Mol Cell Biochem , vol.390 , Issue.1-2 , pp. 19-30
    • Sun, Y.1    Shen, S.2    Liu, X.3
  • 176
    • 84878016872 scopus 로고    scopus 로고
    • Gastric adenocarcinoma has a unique microRNA signature not present in esophageal adenocarcinoma
    • Chen Z, Saad R, Jia P, et al. Gastric adenocarcinoma has a unique microRNA signature not present in esophageal adenocarcinoma. Cancer. 2013;119(11):1985-1993.
    • (2013) Cancer , vol.119 , Issue.11 , pp. 1985-1993
    • Chen, Z.1    Saad, R.2    Jia, P.3
  • 177
    • 77954354936 scopus 로고    scopus 로고
    • Pancreatic cancers epigenetically silence SIP1 and hypomethylate and overexpress miR-200a/200b in association with elevated circulating miR-200a and miR-200b levels
    • Li A, Omura N, Hong SM, et al. Pancreatic cancers epigenetically silence SIP1 and hypomethylate and overexpress miR-200a/200b in association with elevated circulating miR-200a and miR-200b levels. Cancer Res. 2010;70(13):5226-5237.
    • (2010) Cancer Res , vol.70 , Issue.13 , pp. 5226-5237
    • Li, A.1    Omura, N.2    Hong, S.M.3
  • 178
    • 84878130718 scopus 로고    scopus 로고
    • Decreased levels of circulating and tissue miR-107 in human esophageal cancer
    • Sharma P, Saraya A, Gupta P, Sharma R. Decreased levels of circulating and tissue miR-107 in human esophageal cancer. Biomarkers. 2013;18(4):322-330.
    • (2013) Biomarkers , vol.18 , Issue.4 , pp. 322-330
    • Sharma, P.1    Saraya, A.2    Gupta, P.3    Sharma, R.4
  • 179
    • 65449166892 scopus 로고    scopus 로고
    • Epigenetic silencing of MicroRNA miR-107 regulates cyclin-dependent kinase 6 expression in pancreatic cancer
    • Lee KH, Lotterman C, Karikari C, et al. Epigenetic silencing of MicroRNA miR-107 regulates cyclin-dependent kinase 6 expression in pancreatic cancer. Pancreatology. 2009;9(3):293-301.
    • (2009) Pancreatology , vol.9 , Issue.3 , pp. 293-301
    • Lee, K.H.1    Lotterman, C.2    Karikari, C.3
  • 180
    • 84899931775 scopus 로고    scopus 로고
    • MicroRNA-145 inhibits tumour growth and metastasis in colorectal cancer by targeting fascin-1
    • Feng Y, Zhu J, Ou C, et al. MicroRNA-145 inhibits tumour growth and metastasis in colorectal cancer by targeting fascin-1. Br J Cancer. 2014;110(9):2300-2309.
    • (2014) Br J Cancer , vol.110 , Issue.9 , pp. 2300-2309
    • Feng, Y.1    Zhu, J.2    Ou, C.3
  • 181
    • 77954368612 scopus 로고    scopus 로고
    • Association of microRNA expression with microsatellite instability status in colorectal adenocarcinoma
    • Earle JS, Luthra R, Romans A, et al. Association of microRNA expression with microsatellite instability status in colorectal adenocarcinoma. J Mol Diagn. 2010;12(4):433-440.
    • (2010) J Mol Diagn , vol.12 , Issue.4 , pp. 433-440
    • Earle, J.S.1    Luthra, R.2    Romans, A.3
  • 182
    • 84863045238 scopus 로고    scopus 로고
    • Down-regulation of fecal miR-143 and miR-145 as potential markers for colorectal cancer
    • Li JM, Zhao RH, Li ST, et al. Down-regulation of fecal miR-143 and miR-145 as potential markers for colorectal cancer. Saudi Med J. 2012;33(1):24-29.
    • (2012) Saudi Med J , vol.33 , Issue.1 , pp. 24-29
    • Li, J.M.1    Zhao, R.H.2    Li, S.T.3
  • 183
    • 84897036882 scopus 로고    scopus 로고
    • MiR-145, miR-133a and miR-133b inhibit proliferation, migration, invasion and cell cycle progression via targeting transcription factor Sp1 in gastric cancer
    • Qiu T, Zhou X, Wang J, et al. MiR-145, miR-133a and miR-133b inhibit proliferation, migration, invasion and cell cycle progression via targeting transcription factor Sp1 in gastric cancer. FEBS Lett. 2014;588(7):1168-1177.
    • (2014) FEBS Lett , vol.588 , Issue.7 , pp. 1168-1177
    • Qiu, T.1    Zhou, X.2    Wang, J.3
  • 184
    • 84879725337 scopus 로고    scopus 로고
    • Deregulated expression of miR-145 in manifold human cancer cells
    • Xing AY, Wang B, Shi DB, et al. Deregulated expression of miR-145 in manifold human cancer cells. Exp Mol Pathol. 2013;95(1):91-97.
    • (2013) Exp Mol Pathol , vol.95 , Issue.1 , pp. 91-97
    • Xing, A.Y.1    Wang, B.2    Shi, D.B.3
  • 185
    • 84862932892 scopus 로고    scopus 로고
    • microRNA-192, -194 and-215 are frequently downregulated in colorectal cancer
    • Chiang Y, Song Y, Wang Z, et al. microRNA-192, -194 and-215 are frequently downregulated in colorectal cancer. Exp Ther Med. 2012;3(3):560-566.
    • (2012) Exp Ther Med , vol.3 , Issue.3 , pp. 560-566
    • Chiang, Y.1    Song, Y.2    Wang, Z.3
  • 186
    • 84868144684 scopus 로고    scopus 로고
    • Identification and functional screening of microRNAs highly deregulated in colorectal cancer
    • Faltejskova P, Svoboda M, Srutova K, et al. Identification and functional screening of microRNAs highly deregulated in colorectal cancer. J Cell Mol Med. 2012;16(11):2655-2666.
    • (2012) J Cell Mol Med , vol.16 , Issue.11 , pp. 2655-2666
    • Faltejskova, P.1    Svoboda, M.2    Srutova, K.3
  • 187
    • 84856241159 scopus 로고    scopus 로고
    • Invasion front-specific expression and prognostic significance of microRNA in colorectal liver metastases
    • Kahlert C, Klupp F, Brand K, et al. Invasion front-specific expression and prognostic significance of microRNA in colorectal liver metastases. Cancer Sci. 2011;102(10):1799-1807.
    • (2011) Cancer Sci , vol.102 , Issue.10 , pp. 1799-1807
    • Kahlert, C.1    Klupp, F.2    Brand, K.3
  • 188
    • 84865036180 scopus 로고    scopus 로고
    • Inverse association between miR-194 expression and tumor invasion in gastric cancer
    • Song Y, Zhao F, Wang Z, et al. Inverse association between miR-194 expression and tumor invasion in gastric cancer. Ann Surg Oncol. 2012;19 Suppl 3:S509-S517.
    • (2012) Ann Surg Oncol , vol.19 , pp. S509-S517
    • Song, Y.1    Zhao, F.2    Wang, Z.3
  • 189
    • 84887608317 scopus 로고    scopus 로고
    • MiR-215 modulates gastric cancer cell proliferation by targeting RB1
    • Deng Y, Huang Z, Xu Y, et al. MiR-215 modulates gastric cancer cell proliferation by targeting RB1. Cancer Lett. 2014;342(1):27-35.
    • (2014) Cancer Lett , vol.342 , Issue.1 , pp. 27-35
    • Deng, Y.1    Huang, Z.2    Xu, Y.3
  • 190
    • 84855859459 scopus 로고    scopus 로고
    • Serum microRNA-29a is a promising novel marker for early detection of colorectal liver metastasis
    • Wang LG, Gu J. Serum microRNA-29a is a promising novel marker for early detection of colorectal liver metastasis. Cancer Epidemiol. 2012;36(1):e61-e67.
    • (2012) Cancer Epidemiol , vol.36 , Issue.1 , pp. e61-e67
    • Wang, L.G.1    Gu, J.2
  • 191
    • 84892903184 scopus 로고    scopus 로고
    • MicroRNA-29a promotes colorectal cancer metastasis by regulating matrix metalloproteinase 2 and E-cadherin via KLF4
    • Tang W, Zhu Y, Gao J, et al. MicroRNA-29a promotes colorectal cancer metastasis by regulating matrix metalloproteinase 2 and E-cadherin via KLF4. Br J Cancer. 2014;110(2):450-458.
    • (2014) Br J Cancer , vol.110 , Issue.2 , pp. 450-458
    • Tang, W.1    Zhu, Y.2    Gao, J.3
  • 192
    • 84893394683 scopus 로고    scopus 로고
    • miR-29a suppresses growth and invasion of gastric cancer cells in vitro by targeting VEGF-A
    • Chen L, Xiao H, Wang Z-H, et al. miR-29a suppresses growth and invasion of gastric cancer cells in vitro by targeting VEGF-A. BMB Rep. 2014;47(1):39-44.
    • (2014) BMB Rep , vol.47 , Issue.1 , pp. 39-44
    • Chen, L.1    Xiao, H.2    Wang, Z.-H.3
  • 193
    • 79551610902 scopus 로고    scopus 로고
    • miR-605 joins p53 network to form a p53:MiR-605:Mdm2 positive feedback loop in response to stress
    • Xiao J, Lin H, Luo X, Luo X, Wang Z. miR-605 joins p53 network to form a p53:miR-605:Mdm2 positive feedback loop in response to stress. EMBO J. 2011;30(3):524-532.
    • (2011) EMBO J , vol.30 , Issue.3 , pp. 524-532
    • Xiao, J.1    Lin, H.2    Luo, X.3    Luo, X.4    Wang, Z.5
  • 194
    • 80053139025 scopus 로고    scopus 로고
    • MicroRNA-149*, a p53-responsive microRNA, functions as an oncogenic regulator in human melanoma
    • Jin L, Hu WL, Jiang CC, et al. MicroRNA-149*, a p53-responsive microRNA, functions as an oncogenic regulator in human melanoma. Proc Natl Acad Sci U S A. 2011;108(38):15840-15845.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , Issue.38 , pp. 15840-15845
    • Jin, L.1    Hu, W.L.2    Jiang, C.C.3
  • 195
    • 84874940986 scopus 로고    scopus 로고
    • COLOFOL steering group. Non-CpG island promoter hypomethylation and miR-149 regulate the expression of SRPX2 in colorectal cancer
    • Øster B, Linnet L, Christensen LL, et al; COLOFOL steering group. Non-CpG island promoter hypomethylation and miR-149 regulate the expression of SRPX2 in colorectal cancer. Int J Cancer. 2013;132(10):2303-2315.
    • (2013) Int J Cancer , vol.132 , Issue.10 , pp. 2303-2315
    • Øster, B.1    Linnet, L.2    Christensen, L.L.3
  • 196
    • 84872836602 scopus 로고    scopus 로고
    • SP1 mediates the link between methylation of the tumour suppressor miR-149 and outcome in colorectal cancer
    • Wang F, Ma YL, Zhang P, et al. SP1 mediates the link between methylation of the tumour suppressor miR-149 and outcome in colorectal cancer. J Pathol. 2013;229(1):12-24.
    • (2013) J Pathol , vol.229 , Issue.1 , pp. 12-24
    • Wang, F.1    Ma, Y.L.2    Zhang, P.3
  • 197
    • 84868106545 scopus 로고    scopus 로고
    • MicroRNA-149 inhibits proliferation and cell cycle progression through the targeting of ZBTB2 in human gastric cancer
    • Wang Y, Zheng X, Zhang Z, et al. MicroRNA-149 inhibits proliferation and cell cycle progression through the targeting of ZBTB2 in human gastric cancer. PLoS One. 2012;7(10):e41693.
    • (2012) PLoS One , vol.7 , Issue.10
    • Wang, Y.1    Zheng, X.2    Zhang, Z.3
  • 198
    • 84897019409 scopus 로고    scopus 로고
    • A novel p53/microRNA-22/Cyr61 axis in synovial cells regulates inflammation in rheumatoid arthritis
    • Lin J, Huo R, Xiao L, et al. A novel p53/microRNA-22/Cyr61 axis in synovial cells regulates inflammation in rheumatoid arthritis. Arthritis Rheumatol. 2014;66(1):49-59.
    • (2014) Arthritis Rheumatol , vol.66 , Issue.1 , pp. 49-59
    • Lin, J.1    Huo, R.2    Xiao, L.3
  • 199
    • 84880266798 scopus 로고    scopus 로고
    • Clinical significance of miR-22 expression in patients with colorectal cancer
    • Zhang G, Xia S, Tian H, Liu Z, Zhou T. Clinical significance of miR-22 expression in patients with colorectal cancer. Med Oncol. 2012;29(5):3108-3112.
    • (2012) Med Oncol , vol.29 , Issue.5 , pp. 3108-3112
    • Zhang, G.1    Xia, S.2    Tian, H.3    Liu, Z.4    Zhou, T.5
  • 200
    • 78649887520 scopus 로고    scopus 로고
    • Expression profile of microRNAs in serum: A fingerprint for esophageal squamous cell carcinoma
    • Zhang C, Wang C, Chen X, et al. Expression profile of microRNAs in serum: a fingerprint for esophageal squamous cell carcinoma. Clin Chem. 2010;56(12):1871-1879.
    • (2010) Clin Chem , vol.56 , Issue.12 , pp. 1871-1879
    • Zhang, C.1    Wang, C.2    Chen, X.3
  • 202
    • 84875170849 scopus 로고    scopus 로고
    • miR-22 is down-regulated in gastric cancer, and its overexpression inhibits cell migration and invasion via targeting transcription factor Sp1
    • Guo MM, Hu LH, Wang YQ, et al. miR-22 is down-regulated in gastric cancer, and its overexpression inhibits cell migration and invasion via targeting transcription factor Sp1. Med Oncol. 2013;30(2):542.
    • (2013) Med Oncol , vol.30 , Issue.2 , pp. 542
    • Guo, M.M.1    Hu, L.H.2    Wang, Y.Q.3
  • 203
    • 84879077809 scopus 로고    scopus 로고
    • Reduced expression of miR-22 in gastric cancer is related to clinicopathologic characteristics or patient prognosis
    • Wang W, Li F, Zhang Y, Tu Y, Yang Q, Gao X. Reduced expression of miR-22 in gastric cancer is related to clinicopathologic characteristics or patient prognosis. Diagn Pathol. 2013;8:102.
    • (2013) Diagn Pathol , vol.8 , pp. 102
    • Wang, W.1    Li, F.2    Zhang, Y.3    Tu, Y.4    Yang, Q.5    Gao, X.6
  • 204
    • 84887332022 scopus 로고    scopus 로고
    • MicroRNA-22 expression in hepatocellular carcinoma and its correlation with ezrin protein
    • Zhou L, He J, Zhang Y. MicroRNA-22 expression in hepatocellular carcinoma and its correlation with ezrin protein. J Int Med Res. 2013;41(4):1009-1016.
    • (2013) J Int Med Res , vol.41 , Issue.4 , pp. 1009-1016
    • Zhou, L.1    He, J.2    Zhang, Y.3
  • 205
    • 77957982588 scopus 로고    scopus 로고
    • microRNA-22, downregulated in hepatocellular carcinoma and correlated with prognosis, suppresses cell proliferation and tumourigenicity
    • Zhang J, Yang Y, Yang T, et al. microRNA-22, downregulated in hepatocellular carcinoma and correlated with prognosis, suppresses cell proliferation and tumourigenicity. Br J Cancer. 2010;103(8): 1215-1220.
    • (2010) Br J Cancer , vol.103 , Issue.8 , pp. 1215-1220
    • Zhang, J.1    Yang, Y.2    Yang, T.3
  • 206
    • 79957611432 scopus 로고    scopus 로고
    • Human papillomavirus type 16 E6 induces cervical cancer cell migration through the p53/microRNA-23b/urokinase-type plasminogen activator pathway
    • Au Yeung CL, Tsang TY, Yau PL, Kwok TT. Human papillomavirus type 16 E6 induces cervical cancer cell migration through the p53/microRNA-23b/urokinase-type plasminogen activator pathway. Oncogene. 2011;30(21):2401-2410.
    • (2011) Oncogene , vol.30 , Issue.21 , pp. 2401-2410
    • Au Yeung, C.L.1    Tsang, T.Y.2    Yau, P.L.3    Kwok, T.T.4
  • 207
    • 84877147256 scopus 로고    scopus 로고
    • Screening of microRNA in patients with esophageal cancer at same tumor node metastasis stage with different prognoses
    • Zhao BS, Liu SG, Wang TY, et al. Screening of microRNA in patients with esophageal cancer at same tumor node metastasis stage with different prognoses. Asian Pac J Cancer Prev. 2013;14(1): 139-143.
    • (2013) Asian Pac J Cancer Prev , vol.14 , Issue.1 , pp. 139-143
    • Zhao, B.S.1    Liu, S.G.2    Wang, T.Y.3
  • 208
    • 65549097632 scopus 로고    scopus 로고
    • MicroRNA-23b mediates urokinase and c-met downmodulation and a decreased migration of human hepatocellular carcinoma cells
    • Salvi A, Sabelli C, Moncini S, et al. MicroRNA-23b mediates urokinase and c-met downmodulation and a decreased migration of human hepatocellular carcinoma cells. FEBS J. 2009;276(11):2966-2982.
    • (2009) FEBS J , vol.276 , Issue.11 , pp. 2966-2982
    • Salvi, A.1    Sabelli, C.2    Moncini, S.3
  • 209
    • 82555193281 scopus 로고    scopus 로고
    • Genome-wide functional screening of miR-23b as a pleiotropic modulator suppressing cancer metastasis
    • Zhang H, Hao Y, Yang J, et al. Genome-wide functional screening of miR-23b as a pleiotropic modulator suppressing cancer metastasis. Nat Commun. 2011;2:554.
    • (2011) Nat Commun , vol.2 , pp. 554
    • Zhang, H.1    Hao, Y.2    Yang, J.3
  • 210
    • 84864296533 scopus 로고    scopus 로고
    • Oncosuppressive role of p53-induced miR-205 in triple negative breast cancer
    • Piovan C, Palmieri D, Di Leva G, et al. Oncosuppressive role of p53-induced miR-205 in triple negative breast cancer. Mol Oncol. 2012;6(4):458-472.
    • (2012) Mol Oncol , vol.6 , Issue.4 , pp. 458-472
    • Piovan, C.1    Palmieri, D.2    Di Leva, G.3
  • 211
    • 84876698299 scopus 로고    scopus 로고
    • MicroRNA in the pathogenesis and prognosis of esophageal cancer
    • Gu J, Wang Y, Wu X. MicroRNA in the pathogenesis and prognosis of esophageal cancer. Curr Pharm Des. 2013;19(7):1292-1300.
    • (2013) Curr Pharm Des , vol.19 , Issue.7 , pp. 1292-1300
    • Gu, J.1    Wang, Y.2    Wu, X.3
  • 212
    • 84878407662 scopus 로고    scopus 로고
    • Deciphering the unique microRNA signature in human esophageal adenocarcinoma
    • Saad R, Chen Z, Zhu S, et al. Deciphering the unique microRNA signature in human esophageal adenocarcinoma. PLoS One. 2013;8(5): e64463.
    • (2013) PLoS One , vol.8 , Issue.5
    • Saad, R.1    Chen, Z.2    Zhu, S.3
  • 213
    • 84888404527 scopus 로고    scopus 로고
    • Hepatitis B virus X protein inhibits tumor suppressor miR-205 through inducing hypermethylation of miR-205 promoter to enhance carcinogenesis
    • Zhang T, Zhang J, Cui M, et al. Hepatitis B virus X protein inhibits tumor suppressor miR-205 through inducing hypermethylation of miR-205 promoter to enhance carcinogenesis. Neoplasia. 2013;15(11): 1282-1291.
    • (2013) Neoplasia , vol.15 , Issue.11 , pp. 1282-1291
    • Zhang, T.1    Zhang, J.2    Cui, M.3
  • 214
    • 79961022039 scopus 로고    scopus 로고
    • p53 downregulates Down syndrome-associated DYRK1A through miR-1246
    • Zhang Y, Liao JM, Zeng SX, Lu H. p53 downregulates Down syndrome-associated DYRK1A through miR-1246. EMBO Rep. 2011;12(8):811-817.
    • (2011) EMBO Rep , vol.12 , Issue.8 , pp. 811-817
    • Zhang, Y.1    Liao, J.M.2    Zeng, S.X.3    Lu, H.4
  • 215
    • 84859129420 scopus 로고    scopus 로고
    • Mirna expression profiles identify drivers in colorectal and pancreatic cancers
    • Piepoli A, Tavano F, Copetti M, et al. Mirna expression profiles identify drivers in colorectal and pancreatic cancers. PLoS One. 2012;7(3):e33663.
    • (2012) PLoS One , vol.7 , Issue.3
    • Piepoli, A.1    Tavano, F.2    Copetti, M.3
  • 216
    • 84899431845 scopus 로고    scopus 로고
    • Circulating exosomal microRNAs as biomarkers of colon cancer
    • Ogata-Kawata H, Izumiya M, Kurioka D, et al. Circulating exosomal microRNAs as biomarkers of colon cancer. PLoS One. 2014;9(4): e92921.
    • (2014) PLoS One , vol.9 , Issue.4
    • Ogata-Kawata, H.1    Izumiya, M.2    Kurioka, D.3
  • 217
    • 84886596921 scopus 로고    scopus 로고
    • Altered miRNA expression is associated with differentiation, invasion, and metastasis of esophageal squamous cell carcinoma (ESCC) in patients from Huaian, China
    • Fu HL, Wu de P, Wang XF, et al. Altered miRNA expression is associated with differentiation, invasion, and metastasis of esophageal squamous cell carcinoma (ESCC) in patients from Huaian, China. Cell Biochem Biophys. 2013;67(2):657-668.
    • (2013) Cell Biochem Biophys , vol.67 , Issue.2 , pp. 657-668
    • Fu, H.L.1    Wu De, P.2    Wang, X.F.3
  • 218
    • 84875232250 scopus 로고    scopus 로고
    • Serum microRNA expression profile: MiR-1246 as a novel diagnostic and prognostic biomarker for oesophageal squamous cell carcinoma
    • Takeshita N, Hoshino I, Mori M, et al. Serum microRNA expression profile: miR-1246 as a novel diagnostic and prognostic biomarker for oesophageal squamous cell carcinoma. Br J Cancer. 2013;108(3): 644-652.
    • (2013) Br J Cancer , vol.108 , Issue.3 , pp. 644-652
    • Takeshita, N.1    Hoshino, I.2    Mori, M.3
  • 220
    • 78649251518 scopus 로고    scopus 로고
    • MicroRNA expression profiling of exfoliated colonocytes isolated from feces for colorectal cancer screening
    • Koga Y, Yasunaga M, Takahashi A, et al. MicroRNA expression profiling of exfoliated colonocytes isolated from feces for colorectal cancer screening. Cancer Prev Res (Phila). 2010;3(11):1435-1442.
    • (2010) Cancer Prev Res (Phila) , vol.3 , Issue.11 , pp. 1435-1442
    • Koga, Y.1    Yasunaga, M.2    Takahashi, A.3
  • 221
    • 68749119636 scopus 로고    scopus 로고
    • MiR-17-92 cluster is associated with 13q gain and c-myc expression during colorectal adenoma to adenocarcinoma progression
    • Diosdado B, van de Wiel MA, Terhaar Sive Droste JS, et al. MiR-17-92 cluster is associated with 13q gain and c-myc expression during colorectal adenoma to adenocarcinoma progression. Br J Cancer. 2009;101(4):707-714.
    • (2009) Br J Cancer , vol.101 , Issue.4 , pp. 707-714
    • Diosdado, B.1    Van De Wiel, M.A.2    Terhaar Sive Droste, J.S.3
  • 222
    • 84896704806 scopus 로고    scopus 로고
    • MicroRNA-17, microRNA-18a, and microRNA-19a are prognostic indicators in esophageal squamous cell carcinoma
    • Xu XL, Jiang YH, Feng JG, Su D, Chen PC, Mao WM. MicroRNA-17, microRNA-18a, and microRNA-19a are prognostic indicators in esophageal squamous cell carcinoma. Ann Thorac Surg. 2014;97(3): 1037-1045.
    • (2014) Ann Thorac Surg , vol.97 , Issue.3 , pp. 1037-1045
    • Xu, X.L.1    Jiang, Y.H.2    Feng, J.G.3    Su, D.4    Chen, P.C.5    Mao, W.M.6
  • 223
    • 79952322000 scopus 로고    scopus 로고
    • TNF-alpha is a novel target of miR-19a
    • Liu M, Wang Z, Yang S, et al. TNF-alpha is a novel target of miR-19a. Int J Oncol. 2011;38(4):1013-1022.
    • (2011) Int J Oncol , vol.38 , Issue.4 , pp. 1013-1022
    • Liu, M.1    Wang, Z.2    Yang, S.3
  • 224
    • 84907694886 scopus 로고    scopus 로고
    • Circulating miR-18a in plasma contributes to cancer detection and monitoring in patients with gastric cancer. Gastric Cancer
    • Tsujiura M, Komatsu S, Ichikawa D, et al. Circulating miR-18a in plasma contributes to cancer detection and monitoring in patients with gastric cancer. Gastric Cancer. Epub March 14, 2014.
    • (2014) Epub March , pp. 14
    • Tsujiura, M.1    Komatsu, S.2    Ichikawa, D.3
  • 225
    • 84867572582 scopus 로고    scopus 로고
    • H. pylori eradication did not improve dysregulation of specific oncogenic miRNAs in intestinal metaplastic glands
    • Shiotani A, Uedo N, Iishi H, et al. H. pylori eradication did not improve dysregulation of specific oncogenic miRNAs in intestinal metaplastic glands. J Gastroenterol. 2012;47(9):988-998.
    • (2012) J Gastroenterol , vol.47 , Issue.9 , pp. 988-998
    • Shiotani, A.1    Uedo, N.2    Iishi, H.3
  • 226
    • 77951890194 scopus 로고    scopus 로고
    • Deregulation of miR-92a expression is implicated in hepatocellular carcinoma development
    • Shigoka M, Tsuchida A, Matsudo T, et al. Deregulation of miR-92a expression is implicated in hepatocellular carcinoma development. Pathol Int. 2010;60(5):351-357.
    • (2010) Pathol Int , vol.60 , Issue.5 , pp. 351-357
    • Shigoka, M.1    Tsuchida, A.2    Matsudo, T.3
  • 227
    • 81955161862 scopus 로고    scopus 로고
    • Novel diagnostic value of circulating miR-18a in plasma of patients with pancreatic cancer
    • Morimura R, Komatsu S, Ichikawa D, et al. Novel diagnostic value of circulating miR-18a in plasma of patients with pancreatic cancer. Br J Cancer. 2011;105(11):1733-1740.
    • (2011) Br J Cancer , vol.105 , Issue.11 , pp. 1733-1740
    • Morimura, R.1    Komatsu, S.2    Ichikawa, D.3
  • 228
    • 84886052756 scopus 로고    scopus 로고
    • Up-regulation of miR-224 promotes cancer cell proliferation and invasion and predicts relapse of colorectal cancer
    • Zhang GJ, Zhou H, Xiao HX, Li Y, Zhou T. Up-regulation of miR-224 promotes cancer cell proliferation and invasion and predicts relapse of colorectal cancer. Cancer Cell Int. 2013;13(1):104.
    • (2013) Cancer Cell Int , vol.13 , Issue.1 , pp. 104
    • Zhang, G.J.1    Zhou, H.2    Xiao, H.X.3    Li, Y.4    Zhou, T.5
  • 229
    • 84883470363 scopus 로고    scopus 로고
    • microRNA-224 promotes cell proliferation and tumor growth in human colorectal cancer by repressing PHLPP1 and PHLPP2
    • Liao WT, Li TT, Wang ZG, et al. microRNA-224 promotes cell proliferation and tumor growth in human colorectal cancer by repressing PHLPP1 and PHLPP2. Clin Cancer Res. 2013;19(17): 4662-4672.
    • (2013) Clin Cancer Res , vol.19 , Issue.17 , pp. 4662-4672
    • Liao, W.T.1    Li, T.T.2    Wang, Z.G.3
  • 230
    • 84884414160 scopus 로고    scopus 로고
    • Decreased levels of miR-224 and the passenger strand of miR-221 increase MBD2, suppressing maspin and promoting colorectal tumor growth and metastasis in mice
    • Yuan K, Xie K, Fox J, et al. Decreased levels of miR-224 and the passenger strand of miR-221 increase MBD2, suppressing maspin and promoting colorectal tumor growth and metastasis in mice. Gastroenterology. 2013;145(4):853-864. e9.
    • (2013) Gastroenterology , vol.145 , Issue.4 , pp. 853-864
    • Yuan, K.1    Xie, K.2    Fox, J.3
  • 231
    • 84858702208 scopus 로고    scopus 로고
    • Transcriptional regulation of miR-224 upregulated in human HCCs by NFkappaB inflammatory pathways
    • Scisciani C, Vossio S, Guerrieri F, et al. Transcriptional regulation of miR-224 upregulated in human HCCs by NFkappaB inflammatory pathways. J Hepatol. 2012;56(4):855-861.
    • (2012) J Hepatol , vol.56 , Issue.4 , pp. 855-861
    • Scisciani, C.1    Vossio, S.2    Guerrieri, F.3
  • 232
    • 84874363544 scopus 로고    scopus 로고
    • Involvement of microRNA-224 in cell proliferation, migration, invasion, and anti-apoptosis in hepatocellular carcinoma
    • Zhang Y, Takahashi S, Tasaka A, Yoshima T, Ochi H, Chayama K. Involvement of microRNA-224 in cell proliferation, migration, invasion, and anti-apoptosis in hepatocellular carcinoma. J Gastroenterol Hepatol. 2013;28(3):565-575.
    • (2013) J Gastroenterol Hepatol , vol.28 , Issue.3 , pp. 565-575
    • Zhang, Y.1    Takahashi, S.2    Tasaka, A.3    Yoshima, T.4    Ochi, H.5    Chayama, K.6
  • 233
    • 84908886551 scopus 로고    scopus 로고
    • Plasma microRNA profiles: Identification of miR-25 as a novel diagnostic and monitoring biomarker in oesophageal squamous cell carcinoma
    • Komatsu S, Ichikawa D, Hirajima S, et al. Plasma microRNA profiles: identification of miR-25 as a novel diagnostic and monitoring biomarker in oesophageal squamous cell carcinoma. Br J Cancer. 2014.
    • (2014) Br J Cancer
    • Komatsu, S.1    Ichikawa, D.2    Hirajima, S.3
  • 234
    • 84899968241 scopus 로고    scopus 로고
    • A five-microRNA panel in plasma was identified as potential biomarker for early detection of gastric cancer
    • Zhu C, Ren C, Han J, et al. A five-microRNA panel in plasma was identified as potential biomarker for early detection of gastric cancer. Br J Cancer. 2014;110(9):2291-2299.
    • (2014) Br J Cancer , vol.110 , Issue.9 , pp. 2291-2299
    • Zhu, C.1    Ren, C.2    Han, J.3
  • 235
    • 84890531634 scopus 로고    scopus 로고
    • MiR-25 promotes gastric cancer cells growth and motility by targeting RECK
    • Zhao H, Wang Y, Yang L, Jiang R, Li W. MiR-25 promotes gastric cancer cells growth and motility by targeting RECK. Mol Cell Biochem. 2014;385(1-2):207-213.
    • (2014) Mol Cell Biochem , vol.385 , Issue.1-2 , pp. 207-213
    • Zhao, H.1    Wang, Y.2    Yang, L.3    Jiang, R.4    Li, W.5
  • 236
    • 75249107416 scopus 로고    scopus 로고
    • Relation between microRNA expression and progression and prognosis of gastric cancer: A microRNA expression analysis
    • Ueda T, Volinia S, Okumura H, et al. Relation between microRNA expression and progression and prognosis of gastric cancer: a microRNA expression analysis. Lancet Oncol. 2010;11(2):136-146.
    • (2010) Lancet Oncol , vol.11 , Issue.2 , pp. 136-146
    • Ueda, T.1    Volinia, S.2    Okumura, H.3
  • 237
    • 84875279630 scopus 로고    scopus 로고
    • Prognostic implications for high expression of oncogenic microRNAs in advanced gastric carcinoma
    • Kim BH, Hong SW, Kim A, Choi SH, Yoon SO. Prognostic implications for high expression of oncogenic microRNAs in advanced gastric carcinoma. J Surg Oncol. 2013;107(5):505-510.
    • (2013) J Surg Oncol , vol.107 , Issue.5 , pp. 505-510
    • Kim, B.H.1    Hong, S.W.2    Kim, A.3    Choi, S.H.4    Yoon, S.O.5
  • 238
    • 77950622025 scopus 로고    scopus 로고
    • MicroRNA-30d promotes tumor invasion and metastasis by targeting Galphai2 in hepatocellular carcinoma
    • Yao J, Liang L, Huang S, et al. MicroRNA-30d promotes tumor invasion and metastasis by targeting Galphai2 in hepatocellular carcinoma. Hepatology. 2010;51(3):846-856.
    • (2010) Hepatology , vol.51 , Issue.3 , pp. 846-856
    • Yao, J.1    Liang, L.2    Huang, S.3
  • 239
    • 84864501561 scopus 로고    scopus 로고
    • MicroRNA-98 and microRNA-214 post-transcriptionally regulate enhancer of zeste homolog 2 and inhibit migration and invasion in human esophageal squamous cell carcinoma
    • Huang S-D, Yuan Y, Zhuang C-W, et al. MicroRNA-98 and microRNA-214 post-transcriptionally regulate enhancer of zeste homolog 2 and inhibit migration and invasion in human esophageal squamous cell carcinoma. Mol Cancer. 2012;11:51.
    • (2012) Mol Cancer , vol.11 , pp. 51
    • Huang, S.-D.1    Yuan, Y.2    Zhuang, C.-W.3
  • 240
    • 84883454157 scopus 로고    scopus 로고
    • The HER2-miR125a5p/miR125b loop in gastric and esophageal carcinogenesis
    • Fassan M, Pizzi M, Realdon S, et al. The HER2-miR125a5p/miR125b loop in gastric and esophageal carcinogenesis. Hum Pathol. 2013;44(9):1804-1810.
    • (2013) Hum Pathol , vol.44 , Issue.9 , pp. 1804-1810
    • Fassan, M.1    Pizzi, M.2    Realdon, S.3
  • 241
    • 79955513982 scopus 로고    scopus 로고
    • MicroRNA-125a-5p is an independent prognostic factor in gastric cancer and inhibits the proliferation of human gastric cancer cells in combination with trastuzumab
    • Nishida N, Mimori K, Fabbri M, et al. MicroRNA-125a-5p is an independent prognostic factor in gastric cancer and inhibits the proliferation of human gastric cancer cells in combination with trastuzumab. Clin Cancer Res. 2011;17(9):2725-2733.
    • (2011) Clin Cancer Res , vol.17 , Issue.9 , pp. 2725-2733
    • Nishida, N.1    Mimori, K.2    Fabbri, M.3
  • 242
    • 84860271323 scopus 로고    scopus 로고
    • Down-regulation of miR-125a-3p in human gastric cancer and its clinicopathological significance
    • Hashiguchi Y, Nishida N, Mimori K, et al. Down-regulation of miR-125a-3p in human gastric cancer and its clinicopathological significance. Int J Oncol. 2012;40(5):1477-1482.
    • (2012) Int J Oncol , vol.40 , Issue.5 , pp. 1477-1482
    • Hashiguchi, Y.1    Nishida, N.2    Mimori, K.3
  • 243
    • 84863111015 scopus 로고    scopus 로고
    • Ectopic expression of MiR-125a inhibits the proliferation and metastasis of hepatocellular carcinoma by targeting MMP11 and VEGF
    • Bi Q, Tang S, Xia L, et al. Ectopic expression of MiR-125a inhibits the proliferation and metastasis of hepatocellular carcinoma by targeting MMP11 and VEGF. PLoS One. 2012;7(6):e40169.
    • (2012) PLoS One , vol.7 , Issue.6
    • Bi, Q.1    Tang, S.2    Xia, L.3
  • 244
    • 84874487252 scopus 로고    scopus 로고
    • Sirtuin7 oncogenic potential in human hepatocellular carcinoma and its regulation by the tumor suppressors MiR-125a-5p and MiR-125b
    • Kim JK, Noh JH, Jung KH, et al. Sirtuin7 oncogenic potential in human hepatocellular carcinoma and its regulation by the tumor suppressors MiR-125a-5p and MiR-125b. Hepatology. 2013;57(3):1055-1067.
    • (2013) Hepatology , vol.57 , Issue.3 , pp. 1055-1067
    • Kim, J.K.1    Noh, J.H.2    Jung, K.H.3
  • 245
    • 78049521995 scopus 로고    scopus 로고
    • MicroRNA-125b suppressesed human liver cancer cell proliferation and metastasis by directly targeting oncogene LIN28B2
    • Liang L, Wong C-M, Ying Q, et al. MicroRNA-125b suppressesed human liver cancer cell proliferation and metastasis by directly targeting oncogene LIN28B2. Hepatology. 2010;52(5):1731-1740.
    • (2010) Hepatology , vol.52 , Issue.5 , pp. 1731-1740
    • Liang, L.1    Wong, C.-M.2    Ying, Q.3
  • 246
    • 34247862190 scopus 로고    scopus 로고
    • MicroRNA expression patterns to differentiate pancreatic adenocarcinoma from normal pancreas and chronic pancreatitis
    • Bloomston M, Frankel WL, Petrocca F, et al. MicroRNA expression patterns to differentiate pancreatic adenocarcinoma from normal pancreas and chronic pancreatitis. JAMA. 2007;297(17):1901-1908.
    • (2007) JAMA , vol.297 , Issue.17 , pp. 1901-1908
    • Bloomston, M.1    Frankel, W.L.2    Petrocca, F.3
  • 247
    • 84866098272 scopus 로고    scopus 로고
    • miR-150 as a potential biomarker associated with prognosis and therapeutic outcome in colorectal cancer
    • Ma Y, Zhang P, Wang F, et al. miR-150 as a potential biomarker associated with prognosis and therapeutic outcome in colorectal cancer. Gut. 2012;61(10):1447-1453.
    • (2012) Gut , vol.61 , Issue.10 , pp. 1447-1453
    • Ma, Y.1    Zhang, P.2    Wang, F.3
  • 248
    • 84872270291 scopus 로고    scopus 로고
    • MiR-150 is associated with poor prognosis in esophageal squamous cell carcinoma via targeting the EMT inducer ZEB1
    • Yokobori T, Suzuki S, Tanaka N, et al. MiR-150 is associated with poor prognosis in esophageal squamous cell carcinoma via targeting the EMT inducer ZEB1. Cancer Sci. 2013;104(1):48-54.
    • (2013) Cancer Sci , vol.104 , Issue.1 , pp. 48-54
    • Yokobori, T.1    Suzuki, S.2    Tanaka, N.3
  • 249
    • 76349110748 scopus 로고    scopus 로고
    • MiR-150 promotes gastric cancer proliferation by negatively regulating the pro-apoptotic gene EGR2
    • Wu Q, Jin H, Yang Z, et al. MiR-150 promotes gastric cancer proliferation by negatively regulating the pro-apoptotic gene EGR2. Biochem Biophys Res Commun. 2010;392(3):340-345.
    • (2010) Biochem Biophys Res Commun , vol.392 , Issue.3 , pp. 340-345
    • Wu, Q.1    Jin, H.2    Yang, Z.3
  • 250
    • 81855183857 scopus 로고    scopus 로고
    • MicroRNA-150 directly targets MUC4 and suppresses growth and malignant behavior of pancreatic cancer cells
    • Srivastava SK, Bhardwaj A, Singh S, et al. MicroRNA-150 directly targets MUC4 and suppresses growth and malignant behavior of pancreatic cancer cells. Carcinogenesis. 2011;32(12):1832-1839.
    • (2011) Carcinogenesis , vol.32 , Issue.12 , pp. 1832-1839
    • Srivastava, S.K.1    Bhardwaj, A.2    Singh, S.3
  • 251
    • 84878610925 scopus 로고    scopus 로고
    • Prediction value of miR-483 and miR-214 in prognosis and multidrug resistance of esophageal squamous cell carcinoma
    • Zhou Y, Hong L. Prediction value of miR-483 and miR-214 in prognosis and multidrug resistance of esophageal squamous cell carcinoma. Genet Test Mol Biomarkers. 2013;17(6):470-474.
    • (2013) Genet Test Mol Biomarkers , vol.17 , Issue.6 , pp. 470-474
    • Zhou, Y.1    Hong, L.2
  • 252
    • 84879826452 scopus 로고    scopus 로고
    • MiR-214 regulate gastric cancer cell proliferation, migration and invasion by targeting PTEN
    • Yang TS, Yang XH, Wang XD, Wang YL, Zhou B, Song ZS. MiR-214 regulate gastric cancer cell proliferation, migration and invasion by targeting PTEN. Cancer Cell Int. 2013;13(1):68.
    • (2013) Cancer Cell Int , vol.13 , Issue.1 , pp. 68
    • Yang, T.S.1    Yang, X.H.2    Wang, X.D.3    Wang, Y.L.4    Zhou, B.5    Song, Z.S.6
  • 253
    • 84865107292 scopus 로고    scopus 로고
    • MicroRNA-214 downregulation contributes to tumor angiogenesis by inducing secretion of the hepatoma-derived growth factor in human hepatoma
    • Shih TC, Tien YJ, Wen CJ, et al. MicroRNA-214 downregulation contributes to tumor angiogenesis by inducing secretion of the hepatoma-derived growth factor in human hepatoma. J Hepatol. 2012;57(3):584-591.
    • (2012) J Hepatol , vol.57 , Issue.3 , pp. 584-591
    • Shih, T.C.1    Tien, Y.J.2    Wen, C.J.3
  • 254
    • 84866040307 scopus 로고    scopus 로고
    • MiR-214 targets β-catenin pathway to suppress invasion, stem-like traits and recurrence of human hepatocellular carcinoma
    • Xia H, Ooi LL, Hui KM. MiR-214 targets β-catenin pathway to suppress invasion, stem-like traits and recurrence of human hepatocellular carcinoma. PLoS One. 2012;7(9):e44206.
    • (2012) PLoS One , vol.7 , Issue.9
    • Xia, H.1    Ooi, L.L.2    Hui, K.M.3
  • 255
    • 84883826034 scopus 로고    scopus 로고
    • Downregulation of microRNA-214 and overexpression of FGFR-1 contribute to hepatocellular carcinoma metastasis
    • Wang J, Li J, Wang X, Zheng C, Ma W. Downregulation of microRNA-214 and overexpression of FGFR-1 contribute to hepatocellular carcinoma metastasis. Biochem Biophys Res Commun. 2013;439(1):47-53.
    • (2013) Biochem Biophys Res Commun , vol.439 , Issue.1 , pp. 47-53
    • Wang, J.1    Li, J.2    Wang, X.3    Zheng, C.4    Ma, W.5


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