Deregulated expression of miR-145 in manifold human cancer cells

Experimental and Molecular Pathology

Volumn 95, Issue 1, 2013, Pages 91-97

  Xing, Ai Yan ^a   Wang, Bin ^b   Shi, Duan Bo ^a   Zhang, Xiao Fang ^a   Gao, Chao ^c   He, Xiu Quan ^a   Liu, Wen Jun ^a   Gao, Peng ^a  

^a SHANDONG UNIVERSITY   (China)

^b THE FIRST AFFILIATED HOSPITAL OF SHANDONG FIRST MEDICAL UNIVERSITY   (China)

^c SHANDONG UNIVERSITY   (China)

Author keywords

Cell motility; Cell proliferation; MiR 145; Tumor

Indexed keywords

INSULIN RECEPTOR SUBSTRATE 1; MICRORNA 145;

ARTICLE; CANCER CELL; CANCER GROWTH; CANCER INHIBITION; CARCINOGENESIS; CELL MIGRATION; CELL MOTILITY; CELL PROLIFERATION; COLON CANCER; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE TARGETING; GENETIC ANALYSIS; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LIVER CANCER; PHENOTYPE; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOMACH CANCER; TUMOR INVASION; UTERINE CERVIX CANCER; WESTERN BLOTTING;

CELL MOTILITY; CELL PROLIFERATION; MIR-145; TUMOR;

CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; COLONIC NEOPLASMS; DOWN-REGULATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, TUMOR SUPPRESSOR; HUMANS; INSULIN RECEPTOR SUBSTRATE PROTEINS; LIVER NEOPLASMS; MICRORNAS; REFERENCE VALUES; STOMACH NEOPLASMS; TUMOR STEM CELL ASSAY; UTERINE CERVICAL NEOPLASMS;

EID: 84879725337     PISSN: 00144800     EISSN: 10960945     Source Type: Journal    
DOI: 10.1016/j.yexmp.2013.05.003     Document Type: Article

References (36)

1. Bartel D.P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004, 116:281-297.
2. Calin G.A., Sevignani C., Dumitru C.D., et al. Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proceedings of the National Academy of Sciences of the United States of America 2004, 101:2999-3004.
3. Chehrehasa F., Meedeniya A.C., Dwyer P., et al. EdU, a new thymidine analogue for labelling proliferating cells in the nervous system. Journal of Neuroscience Methods 2009, 177:122-130.
4. Chen C., Ridzon D.A., Broomer A.J., et al. Real-time quantification of microRNAs by stem-loop RT-PCR. Nucleic Acids Research 2005, 33:e179.
5. Chen X., Gong J., Zeng H., et al. MicroRNA145 targets BNIP3 and suppresses prostate cancer progression. Cancer Research 2010, 70:2728-2738.
6. Chen Z., Zeng H., Guo Y., et al. miRNA-145 inhibits non-small cell lung cancer cell proliferation by targeting c-Myc. Journal of Experimental & Clinical Cancer Research 2010, 29:151.
7. Chiyomaru T., Enokida H., Tatarano S., et al. miR-145 and miR-133a function as tumor suppressors and directly regulates FSCN1 expression in bladder cancer. British Journal of Cancer 2010, 102:883-891.
8. Cordes K.R., Sheehy N.T., White M.P., et al. miR-145 and miR-143 regulate smooth muscle cell fate and plasticity. Nature 2009, 460:705-710.
9. Cristofanelli B., Valentinis B., Soddu S., et al. Cooperative transformation of 32D cells by thecombined expression of IRS-1 and V-Ha-Ras. Oncogene 2000, 19:3245-3255.
10. de Krijger I., Mekenkamp L.J., Punt C.J., et al. MicroRNAs in colorectal cancer metastasis. The Journal of Pathology 2011, 224:438-447.
11. Farazi T.A., Spitzer J.I., Morozov P., et al. miRNAs in human cancer. The Journal of Pathology 2011, 223:102-115.
12. Ferracin M., Pedriali M., Veronese A., et al. MicroRNA profiling for the identification of cancers with unknown primary tissue-of-origin. The Journal of Pathology 2011, 225:43-53.
13. Gao P., Wong C.C., Tung E.K., et al. Deregulation of microRNA expression occurs early and accumulates in early stages of HBV-associated multistep hepatocarcinogenesis. Journal of Hepatology 2011, 54:1177-1184.
14. Gramantieri L., Ferracin M., Fornari F., et al. Cyclin G1 is a target of miR-122a, a microRNA frequently down-regulated in human hepatocellular carcinoma. Cancer Research 2007, 67:6092-6099.
15. Larsson E., Fredlund Fuchs P., Heldin J., et al. Discovery of microvascular miRNAs using public gene expression data: miR-145 is expressed in pericytes and is a regulator of Fli1. Genome Medicine 2009, 1:108.
16. Lim L.P., Lau N.C., Garrett-Engele P., et al. Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature 2005, 433:769-773.
17. Liu X., Sempere L.F., Galimberti F., et al. Uncovering growth-suppressive MicroRNAs in lung cancer. Clinical Cancer Research 2009, 15:1177-1183.
18. Lu J., Getz G., Miska E.A., et al. MicroRNA expression profiles classify human cancers. Nature 2005, 435:834-838.
19. Ma L., Teruya-Feldstein J., Weinberg R.A. Tumour invasion and metastasis initiated by microRNA-10b in breast cancer. Nature 2007, 44:682-688.
20. Meng F., Henson R., Wehbe-Janek H., et al. MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology 2007, 133:647-658.
21. Nicoloso M.S., Spizzo R., Shimizu M., et al. MicroRNAs - the micro steering wheel of tumour metastases. Nature Reviews Cancer 2009, 9:293-302.
22. Sachdeva M., Mo Y.Y. MicroRNA-145 suppresses cell invasion and metastasis by directly targeting mucin1. Cancer Research 2010, 70:378-387.
23. Sachdeva M., Zhu S., Wu F., et al. p53 represses c-Myc through induction of the tumor suppressor miR-145. Proceedings of the National Academy of Sciences of the United States of America 2009, 106:3207-3212.
24. Schepeler T., Reinert J.T., Ostenfeld M.S., et al. Diagnostic and prognostic microRNAs in stage II colon cancer. Cancer Research 2008, 68:6416-6424.
25. Shi B., Sepp-Lorenzino L., Prisco M., et al. MicroRNA145 targets the insulin receptor substrate-1 and inhibits the growth of colon cancer cells. Journal of Biological Chemistry 2007, 282:32582-32590.
26. Spizzo R., Nicoloso M.S., Lupini L., et al. miR-145 participates with TP53 in a death-promoting regulatory loop and targets estrogen receptor-alpha in human breast cancer cells. Cell Death and Differentiation 2010, 17:246-254.
27. Suzuki H.I., Yamagata K., Sugimoto K., et al. Modulation of microRNA processing by p53. Nature 2009, 460:529-533.
28. Vaksman O., Stavnes H.T., Kaern J., et al. miRNA profiling along tumour progression in ovarian carcinoma. Journal of Cellular and Molecular Medicine 2011, 15:1593-1602.
29. Valastyan S., Reinhardt F., Benaich N., et al. A pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis. Cell 2009, 137:1032-1046.
30. Volinia S., Calin G.A., Liu C.G., et al. A microRNA expression signature of human solid tumors defines cancer gene targets. Proceedings of the National Academy of Sciences of the United States of America 2006, 103:2257-2261.
31. Vriens M.R., Weng J., Suh I., et al. MicroRNA expression profiling is a potential diagnostic tool for thyroid cancer. Cancer 2012, 118:3426-3432.
32. Wang Y., Lee A.T., Ma J.Z., et al. Profiling microRNA expression in hepatocellular carcinoma reveals microRNA-224 up-regulation and apoptosis inhibitor-5 as a microRNA-224 specific target. Journal of Biological Chemistry 2008, 283:13205-13215.
33. Wang L., Tang H., Thayanithy V., et al. Gene networks and microRNAs implicated in aggressive prostate cancer. Cancer Research 2009, 69:9490-9497.
34. Wang J., Wang Q., Liu H., et al. MicroRNA expression and its implication for the diagnosis and therapeutic strategies of gastric cancer. Cancer Letters 2010, 297:137-143.
35. Xu N., Papagiannakopoulos T., Pan G., et al. MicroRNA-145 regulated OCT4, SOX2 and KLF4 and represses pluripotency in human embryonic stem cells. Cell 2009, 137:647-658.
36. Zimmerman A.L., Wu S. MicroRNAs, cancer and cancer stem cells. Cancer Letters 2011, 300:10-19.