-
1
-
-
0034659964
-
The natural history, skeletal complications, and management of bone metastases in patients with prostate carcinoma
-
Carlin BI and Andriole GL: The natural history, skeletal complications, and management of bone metastases in patients with prostate carcinoma. Cancer 88:2989-2994, 2008.
-
(2008)
Cancer
, vol.88
, pp. 2989-2994
-
-
Carlin, B.I.1
Andriole, G.L.2
-
2
-
-
65349103899
-
Blinded by the light: The growing complexity of p53
-
Vousden KH and Prives C: Blinded by the light: the growing complexity of p53. Cell 137:413-431, 2009.
-
(2009)
Cell
, vol.137
, pp. 413-431
-
-
Vousden, K.H.1
Prives, C.2
-
3
-
-
78650015522
-
The role of mutant p53 in human cancer
-
Goh AM, Coffill CR and Lane DP: The role of mutant p53 in human cancer. J Pathol 223:116-126, 2011.
-
(2011)
J Pathol
, vol.223
, pp. 116-126
-
-
Goh, A.M.1
Coffill, C.R.2
Lane, D.P.3
-
4
-
-
78951475020
-
P53 and its mutants in tumor cell migration and invasion
-
Muller PA, Vousden KH and Norman JC: p53 and its mutants in tumor cell migration and invasion. J Cell Biol 192:209-218, 2011.
-
(2011)
J Cell Biol
, vol.192
, pp. 209-218
-
-
Muller, P.A.1
Vousden, K.H.2
Norman, J.C.3
-
5
-
-
0032876470
-
P53 mutations in prostate cancer bone metastases suggest that selected p53 mutants in the primary site define foci with metastatic potential
-
Navone NM, Labate ME, Troncoso P, Pisters LL, Conti CJ, Von Eschenbach AC and Logothetis CJ: p53 mutations in prostate cancer bone metastases suggest that selected p53 mutants in the primary site define foci with metastatic potential. J Urol 161:304-308, 1999.
-
(1999)
J Urol
, vol.161
, pp. 304-308
-
-
Navone, N.M.1
Labate, M.E.2
Troncoso, P.3
Pisters, L.L.4
Conti, C.J.5
Von Eschenbach, A.C.6
Logothetis, C.J.7
-
6
-
-
67349166210
-
P53 controls cancer cell invasion by inducing the MDM2-mediated degradation of Slug
-
Wang SP, Wang WL, Chang YL, et al: p53 controls cancer cell invasion by inducing the MDM2-mediated degradation of Slug. Nat Cell Biol 11:694-704, 2009.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 694-704
-
-
Wang, S.P.1
Wang, W.L.2
Chang, Y.L.3
-
7
-
-
78449297894
-
The guardians of the genome (p53, TA-p73, and TA-p63) are regulators of tumor suppressor miRNAs network
-
Boominathan L: The guardians of the genome (p53, TA-p73, and TA-p63) are regulators of tumor suppressor miRNAs network. Cancer Metastasis Rev 29:613-639, 2010.
-
(2010)
Cancer Metastasis Rev
, vol.29
, pp. 613-639
-
-
Boominathan, L.1
-
8
-
-
79952283482
-
P53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAs
-
Chang CJ, Chao CH, Xia W, et al: p53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAs. Nat Cell Biol 13:317-323, 2011.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 317-323
-
-
Chang, C.J.1
Chao, C.H.2
Xia, W.3
-
9
-
-
84855729906
-
A p53/miRNA-34 axis regulates Snail1-dependent cancer cell epithelial-mesenchymal transition
-
Kim NH, Kim HS, Li XY, et al: A p53/miRNA-34 axis regulates Snail1-dependent cancer cell epithelial-mesenchymal transition. J Cell Biol 195:417-433, 2011.
-
(2011)
J Cell Biol
, vol.195
, pp. 417-433
-
-
Kim, N.H.1
Kim, H.S.2
Li, X.Y.3
-
10
-
-
79956143950
-
P53 regulates epithelial-mesenchymal transition through microRNAs targeting ZEB1 and ZEB2
-
Kim T, Veronese A, Pichiorri F, et al: p53 regulates epithelial- mesenchymal transition through microRNAs targeting ZEB1 and ZEB2. J Exp Med 208:875-883, 2011.
-
(2011)
J Exp Med
, vol.208
, pp. 875-883
-
-
Kim, T.1
Veronese, A.2
Pichiorri, F.3
-
11
-
-
79955628616
-
P53 spreads out further: Suppression of EMT and stemness by activating miR-200c expression
-
Schubert J and Brabletz T: p53 spreads out further: suppression of EMT and stemness by activating miR-200c expression. Cell Res 21:705-707, 2011.
-
(2011)
Cell Res
, vol.21
, pp. 705-707
-
-
Schubert, J.1
Brabletz, T.2
-
12
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan D and Weinberg RA: Hallmarks of cancer: the next generation. Cell 144:646-674, 2011.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
13
-
-
78650223132
-
Molecular signature of epithelial-mesenchymal transition (EMT) in human prostate cancer bone metastasis
-
Sethi S, Macoska J, Chen W and Sarkar FH: Molecular signature of epithelial-mesenchymal transition (EMT) in human prostate cancer bone metastasis. Am J Transl Res 3:90-99, 2010.
-
(2010)
Am J Transl Res
, vol.3
, pp. 90-99
-
-
Sethi, S.1
Macoska, J.2
Chen, W.3
Sarkar, F.H.4
-
14
-
-
34848826864
-
Epithelial-mesenchymal and mesenchymal-epithelial transitions in carcinoma progression
-
Hugo H, Ackland ML, Blick T, Lawrence MG, Clements JA, Williams ED and Thompson EW: Epithelial-mesenchymal and mesenchymal-epithelial transitions in carcinoma progression. J Cell Physiol 213:374-383, 2007.
-
(2007)
J Cell Physiol
, vol.213
, pp. 374-383
-
-
Hugo, H.1
Ackland, M.L.2
Blick, T.3
Lawrence, M.G.4
Clements, J.A.5
Williams, E.D.6
Thompson, E.W.7
-
15
-
-
52549087785
-
Cancer stem cells in solid tumours: Accumulating evidence and unresolved questions
-
Visvader JE and Lindeman GJ: Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nat Rev Cancer 8:755-768, 2008.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 755-768
-
-
Visvader, J.E.1
Lindeman, G.J.2
-
16
-
-
79953147370
-
A perspective on cancer cell metastasis
-
Chaffer CL and Weinberg RA: A perspective on cancer cell metastasis. Science 331:1559-1564, 2011.
-
(2011)
Science
, vol.331
, pp. 1559-1564
-
-
Chaffer, C.L.1
Weinberg, R.A.2
-
17
-
-
77950591041
-
Cancer stemness and metastasis: Therapeutic consequences and perspectives
-
Monteiro J and Fodde R: Cancer stemness and metastasis: therapeutic consequences and perspectives. Eur J Cancer 46:1198-1203, 2010.
-
(2010)
Eur J Cancer
, vol.46
, pp. 1198-1203
-
-
Monteiro, J.1
Fodde, R.2
-
19
-
-
43049103824
-
The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
-
Gregory PA, Bert AG, Paterson EL, et al: The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nat Cell Biol 10:593-601, 2008.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 593-601
-
-
Gregory, P.A.1
Bert, A.G.2
Paterson, E.L.3
-
20
-
-
47249091921
-
The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2
-
Korpal M, Lee ES, Hu G and Kang Y: The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2. J Biol Chem 283:14910-14914, 2008.
-
(2008)
J Biol Chem
, vol.283
, pp. 14910-14914
-
-
Korpal, M.1
Lee, E.S.2
Hu, G.3
Kang, Y.4
-
21
-
-
79751473114
-
The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44
-
Liu C, Kelnar K, Liu B, et al: The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44. Nat Med 17:211-215, 2011.
-
(2011)
Nat Med
, vol.17
, pp. 211-215
-
-
Liu, C.1
Kelnar, K.2
Liu, B.3
-
22
-
-
84055184850
-
MiR-34 and SNAIL form a doublenegative feedback loop to regulate epithelial-mesenchymal transitions
-
Siemens H, Jackstadt R, Hünten S, Kaller M, Menssen A, Götz U and Hermeking H: miR-34 and SNAIL form a doublenegative feedback loop to regulate epithelial-mesenchymal transitions. Cell Cycle 10:4256-4271, 2011.
-
(2011)
Cell Cycle
, vol.10
, pp. 4256-4271
-
-
Siemens, H.1
Jackstadt, R.2
Hünten, S.3
Kaller, M.4
Menssen, A.5
Götz, U.6
Hermeking, H.7
-
24
-
-
84866423871
-
MicroRNAs in the p53 network: Micromanagement of tumour suppression
-
Hermeking H: MicroRNAs in the p53 network: micromanagement of tumour suppression. Nat Rev Cancer 12:613-626, 2012.
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 613-626
-
-
Hermeking, H.1
-
25
-
-
79957599227
-
Identification of miRs-143 and -145 that is associated with bone metastasis of prostate cancer and involved in the regulation of EMT
-
Peng X, Guo W, Liu T, et al: Identification of miRs-143 and -145 that is associated with bone metastasis of prostate cancer and involved in the regulation of EMT. PLoS One 6:e20341, 2011.
-
(2011)
PLoS One
, vol.6
-
-
Peng, X.1
Guo, W.2
Liu, T.3
-
26
-
-
84866464390
-
MiR-143 and miR-145 inhibit stem cell characteristics of PC-3 prostate cancer cells
-
Huang S, Guo W, Tang Y, Ren D, Zou X and Peng X: miR-143 and miR-145 inhibit stem cell characteristics of PC-3 prostate cancer cells. Oncol Rep 28:1831-1837, 2012.
-
(2012)
Oncol Rep
, vol.28
, pp. 1831-1837
-
-
Huang, S.1
Guo, W.2
Tang, Y.3
Ren, D.4
Zou, X.5
Peng, X.6
-
27
-
-
62549148270
-
P53 represses c-Myc through induction of the tumor suppressor miR-145
-
Sachdeva M, Zhu S, Wu F, et al: p53 represses c-Myc through induction of the tumor suppressor miR-145. Proc Natl Acad Sci USA 106:3207-3212, 2009.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 3207-3212
-
-
Sachdeva, M.1
Zhu, S.2
Wu, F.3
-
28
-
-
67749143728
-
Modulation of microRNA processing by p53
-
Suzuki HI, Yamagata K, Sugimoto K, Iwamoto T, Kato S and Miyazono K: Modulation of microRNA processing by p53. Nature 460:529-533, 2009.
-
(2009)
Nature
, vol.460
, pp. 529-533
-
-
Suzuki, H.I.1
Yamagata, K.2
Sugimoto, K.3
Iwamoto, T.4
Kato, S.5
Miyazono, K.6
-
29
-
-
84866248074
-
Glucocorticoid regulation of a novel HPV-E6-p53-miR-145 pathway modulates invasion and therapy resistance of cervical cancer cells
-
Shi M, Du L, Liu D, et al: Glucocorticoid regulation of a novel HPV-E6-p53-miR-145 pathway modulates invasion and therapy resistance of cervical cancer cells. J Pathol 228:148-157, 2011.
-
(2011)
J Pathol
, vol.228
, pp. 148-157
-
-
Shi, M.1
Du, L.2
Liu, D.3
-
30
-
-
79955771439
-
MicroRNA-145 is regulated by DNA methylation and p53 gene mutation in prostate cancer
-
Suh SO, Chen Y, Zaman MS, et al: MicroRNA-145 is regulated by DNA methylation and p53 gene mutation in prostate cancer. Carcinogenesis 32:772-778, 2011.
-
(2011)
Carcinogenesis
, vol.32
, pp. 772-778
-
-
Suh, S.O.1
Chen, Y.2
Zaman, M.S.3
-
31
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2 (-Delta Delta C (T)) method
-
Schmittgen TD and Livak KJ: Analysis of relative gene expression data using real-time quantitative PCR and the 2 (-Delta Delta C (T)) method. Methods 25:402-408, 2011.
-
(2011)
Methods
, vol.25
, pp. 402-408
-
-
Schmittgen, T.D.1
Livak, K.J.2
-
32
-
-
72149118717
-
Stem cell characteristics in prostate cancer cell lines
-
Pfeiffer MJ and Schalken JA: Stem cell characteristics in prostate cancer cell lines. Eur Urol 57:246-254, 2010.
-
(2010)
Eur Urol
, vol.57
, pp. 246-254
-
-
Pfeiffer, M.J.1
Schalken, J.A.2
-
33
-
-
67649948804
-
WNT signaling regulates self-renewal and differentiation of prostate cancer cells with stem cell characteristics
-
Bisson I and Prowse DM: WNT signaling regulates self-renewal and differentiation of prostate cancer cells with stem cell characteristics. Cell Res 19:683-697, 2009.
-
(2009)
Cell Res
, vol.19
, pp. 683-697
-
-
Bisson, I.1
Prowse, D.M.2
-
34
-
-
67349149082
-
MicroRNA-145 regulates OCT-4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells
-
Xu N, Papagiannakopoulos T, Pan G, Thomson JA and Kosik KS: MicroRNA-145 regulates OCT-4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells. Cell 137:647-658, 2009.
-
(2009)
Cell
, vol.137
, pp. 647-658
-
-
Xu, N.1
Papagiannakopoulos, T.2
Pan, G.3
Thomson, J.A.4
Kosik, K.S.5
-
35
-
-
0242490099
-
Elevated levels of prostate-specific antigen (PSA) in prostate cancer cells expressing mutant p53 is associated with tumor metastasis
-
Downing S, Bumak C, Nixdorf S, Ow K, Russell P and Jackson P: Elevated levels of prostate-specific antigen (PSA) in prostate cancer cells expressing mutant p53 is associated with tumor metastasis. Mol Carcinog 38:130-140, 2003.
-
(2003)
Mol Carcinog
, vol.38
, pp. 130-140
-
-
Downing, S.1
Bumak, C.2
Nixdorf, S.3
Ow, K.4
Russell, P.5
Jackson, P.6
-
36
-
-
0030754058
-
Primary human prostate cancer cells harboring p53 mutations are clonally expanded in metastases
-
Stapleton AM, Timme TL, Gousse AE, et al: Primary human prostate cancer cells harboring p53 mutations are clonally expanded in metastases. Clin Cancer Res 3:1389-1397, 1997.
-
(1997)
Clin Cancer Res
, vol.3
, pp. 1389-1397
-
-
Stapleton, A.M.1
Timme, T.L.2
Gousse, A.E.3
-
37
-
-
78651289008
-
Mutant p53 (R175H) upregulates Twist1 expression and promotes epithelial-mesenchymal transition in immortalized prostate cells
-
Kogan-Sakin I, Tabach Y, Buganim Y, et al: Mutant p53 (R175H) upregulates Twist1 expression and promotes epithelial-mesenchymal transition in immortalized prostate cells. Cell Death Differ 18:271-281, 2011.
-
(2011)
Cell Death Differ
, vol.18
, pp. 271-281
-
-
Kogan-Sakin, I.1
Tabach, Y.2
Buganim, Y.3
-
38
-
-
84870007145
-
Initiation of prostate cancer in mice by Tp53R270H: Evidence for an alternative molecular progression
-
Vinall RL, Chen JQ, Hubbard NE, Sulaimon SS, Shen MM, Devere White RW and Borowsky AD: Initiation of prostate cancer in mice by Tp53R270H: evidence for an alternative molecular progression. Dis Model Mech 5:914-920, 2012.
-
(2012)
Dis Model Mech
, vol.5
, pp. 914-920
-
-
Vinall, R.L.1
Chen, J.Q.2
Hubbard, N.E.3
Sulaimon, S.S.4
Shen, M.M.5
Devere White, R.W.6
Borowsky, A.D.7
-
39
-
-
33748078111
-
Synergy of p53 and Rb deficiency in a conditional mouse model for metastatic prostate cancer
-
Zhou Z, Flesken-Nikitin A, Corney DC, Wang W, Goodrich DW, Roy-Burman P and Nikitin AY: Synergy of p53 and Rb deficiency in a conditional mouse model for metastatic prostate cancer. Cancer Res 66:7889-7898, 2006.
-
(2006)
Cancer Res
, vol.66
, pp. 7889-7898
-
-
Zhou, Z.1
Flesken-Nikitin, A.2
Corney, D.C.3
Wang, W.4
Goodrich, D.W.5
Roy-Burman, P.6
Nikitin, A.Y.7
-
40
-
-
34250822389
-
Prostate cancer associated with p53 and Rb deficiency arises from the stem/progenitor cell-enriched proximal region of prostatic ducts
-
Zhou Z, Flesken-Nikitin A and Nikitin AY: Prostate cancer associated with p53 and Rb deficiency arises from the stem/progenitor cell-enriched proximal region of prostatic ducts. Cancer Res 67:5683-5690, 2007.
-
(2007)
Cancer Res
, vol.67
, pp. 5683-5690
-
-
Zhou, Z.1
Flesken-Nikitin, A.2
Nikitin, A.Y.3
-
41
-
-
80052461278
-
Prostate epithelial Pten/TP53 loss leads to transformation of multipotential progenitors and epithelial to mesenchymal transition
-
Martin P, Liu YN, Pierce R, et al: Prostate epithelial Pten/TP53 loss leads to transformation of multipotential progenitors and epithelial to mesenchymal transition. Am J Pathol 179:422-435, 2011.
-
(2011)
Am J Pathol
, vol.179
, pp. 422-435
-
-
Martin, P.1
Liu, Y.N.2
Pierce, R.3
-
42
-
-
84880298880
-
Mutant p53 gain-of-function induces epithelial-mesenchymal transition through modulation of the miR-130b-ZEB1 axis
-
Jul. 30, doi: 10.1038/onc.2012.334
-
Dong P, Karaayvaz M, Jia N, et al: Mutant p53 gain-of-function induces epithelial-mesenchymal transition through modulation of the miR-130b-ZEB1 axis. Oncogene: Jul. 30, 2012 (Epub ahead of print). doi: 10.1038/onc.2012.334.
-
(2012)
Oncogene
-
-
Dong, P.1
Karaayvaz, M.2
Jia, N.3
-
43
-
-
84873057723
-
The molecular mechanism of microRNA-145 to suppress invasion-metastasis cascade in gastric cancer
-
Gao P, Xing AY, Zhou GY, et al: The molecular mechanism of microRNA-145 to suppress invasion-metastasis cascade in gastric cancer. Oncogene 32:491-501, 2013.
-
(2013)
Oncogene
, vol.32
, pp. 491-501
-
-
Gao, P.1
Xing, A.Y.2
Zhou, G.Y.3
-
44
-
-
43049165453
-
The epithelial-mesenchymal transition generates cells with properties of stem cells
-
Mani SA, Guo W, Liao MJ, et al: The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 133:704-715, 2008.
-
(2008)
Cell
, vol.133
, pp. 704-715
-
-
Mani, S.A.1
Guo, W.2
Liao, M.J.3
-
45
-
-
77957902732
-
Epithelial to mesenchymal transition is mechanistically linked with stem cell signatures in prostate cancer cells
-
Kong D, Banerjee S, Ahmad A, Li Y, Wang Z, Sethi S and Sarkar FH: Epithelial to mesenchymal transition is mechanistically linked with stem cell signatures in prostate cancer cells. PLoS One 5:e12445, 2010.
-
(2010)
PLoS One
, vol.5
-
-
Kong, D.1
Banerjee, S.2
Ahmad, A.3
Li, Y.4
Wang, Z.5
Sethi, S.6
Sarkar, F.H.7
|