Reduced expression of miR-22 in gastric cancer is related to clinicopathologic characteristics or patient prognosis

Diagnostic Pathology

Volumn 8, Issue 1, 2013, Pages

  Wang, Weibin ^a   Li, Fujun ^a   Zhang, Yong ^b   Tu, Yanyang ^c   Yang, Qi ^c   Gao, Xingchun ^c  

^a Department of General Surgery   (China)

^b Department of Lanzhou Military region ^*  (China)

^c FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Gastric cancer; MicroRNA 22; Prognosis; Quantitative RT PCR

Indexed keywords

MICRORNA; MIRN22 MICRORNA, HUMAN; TUMOR MARKER;

ADULT; AGED; ARTICLE; DOWN REGULATION; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; HUMAN; LYMPH NODE METASTASIS; MALE; METHODOLOGY; MIDDLE AGED; MORTALITY; PATHOLOGY; PHYSIOLOGY; PROGNOSIS; STOMACH TUMOR; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; DOWN-REGULATION; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LYMPHATIC METASTASIS; MALE; MICRORNAS; MIDDLE AGED; PROGNOSIS; STOMACH NEOPLASMS; TUMOR MARKERS, BIOLOGICAL; YOUNG ADULT;

EID: 84879077809     PISSN: None     EISSN: 17461596     Source Type: Journal    
DOI: 10.1186/1746-1596-8-102     Document Type: Article

References (26)

1. Siegel R, Naishadham D, Jemal A. Cancer statistics, 2013. CA Cancer J Clin 2013, 63:11-30. 10.3322/caac.21166, 23335087.
2. Ye YW, Dong RZ, Zhou Y, Du CY, Wang CM, Fu H, Shi YQ. Prognostic analysis of familial gastric cancer in Chinese population. J Surg Oncol 2011, 104:76-82. 10.1002/jso.21896, 21400534.
3. Shan L, Ying J, Lu N. HER2 expression and relevant clinicopathological features in gastric and gastroesophageal junction adenocarcinoma in a Chinese population. Diagn Pathol 2013, 8:76. 10.1186/1746-1596-8-76, 3655831, 23656792.
4. Liu X, Xiong H, Li J, He Y, Yuan X. Correlation of hK6 expression with tumor recurrence and prognosis in advanced gastric cancer. Diagn Pathol 2013, 8:62. 10.1186/1746-1596-8-62, 3674969, 23587030.
5. Wu WK, Lee CW, Cho CH, Fan D, Wu K, Yu J, Sung JJ. MicroRNA dysregulation in gastric cancer: a new player enters the game. Oncogene 2010, 29:5761-5771. 10.1038/onc.2010.352, 20802530.
6. Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global cancer statistics. CA Cancer J Clin 2011, 61:69-90. 10.3322/caac.20107, 21296855.
7. Zhang YZ, Zhang LH, Gao Y, Li CH, Jia SQ, Liu N, Cheng F, Niu DY, Cho WC, Ji JF, Zeng CQ. Discovery and validation of prognostic markers in gastric cancer by genome-wide expression profiling. World J Gastroenterol 2011, 17:1710-1717. 10.3748/wjg.v17.i13.1710, 3072635, 21483631.
8. Jia YF, Xiao DJ, Ma XL, Song YY, Hu R, Kong Y, Zheng Y, Han SY, Hong RL, Wang YS. Differentiated embryonic chondrocyte-expressed gene 1 is associated with hypoxia-inducible factor 1α and Ki67 in human gastric cancer. Diagn Pathol 2013, 8:37. 10.1186/1746-1596-8-37, 3606391, 23445622.
9. Jin J, Jin T, Quan M, Piao Y, Lin Z. Ezrin overexpression predicts the poor prognosis of gastric adenocarcinoma. Diagn Pathol 2012, 7:135. 10.1186/1746-1596-7-135, 3502371, 23039327.
10. Sotoudeh K, Hashemi F, Madjd Z, Sadeghipour A, Molanaei S, Kalantary E. The clinicopathologic association of c-MET overexpression in Iranian gastric carcinomas; an immunohistochemical study of tissue microarrays. Diagn Pathol 2012, 7:57. 10.1186/1746-1596-7-57, 3408322, 22640970.
11. Doench JG, Sharp PA. Specificity of microRNA target selection in translational repression. Genes Dev 2004, 18:504-511. 10.1101/gad.1184404, 374233, 15014042.
12. Esquela-Kerscher A, Slack FJ. Oncomirs-microRNAs with a role in cancer. Nat Rev Cancer 2006, 6:259-269.
13. Link A, Kupcinskas J, Wex T, Malfertheiner P. Macro-role of microRNA in gastric cancer. Dig Dis 2012, 30:255-267. 10.1159/000336919, 22722550.
14. Song MY, Pan KF, Su HJ, Zhang L, Ma JL, Li JY, Yuasa Y, Kang D, Kim YS, You WC. Identification of serum microRNAs as novel non-invasive biomarkers for early detection of gastric cancer. PLoS One 2012, 7:e33608. 10.1371/journal.pone.0033608, 3303856, 22432036.
15. Yang Q, Zhang C, Huang B, Li HY, Zhang R, Huang YX, Wang JJ. Downregulation of microRNA-206 is a Potent Prognostic Marker for Patients with Gastric Cancer. Eur J Gastroenterol Hepatol 2013, In press.
16. Zhang J, Yang Y, Yang T, Liu Y, Li A, Fu S, Wu M, Pan Z, Zhou W. MicroRNA-22, downregulated in hepatocellular carcinoma and correlated with prognosis, suppresses cell proliferation and tumourigenicity. Br J Cancer 2010, 103:1215-1220. 10.1038/sj.bjc.6605895, 2967065, 20842113.
17. Xiong J, Yu D, Wei N, Fu H, Cai T, Huang Y, Wu C, Zheng X, Du Q, Lin D, Liang Z. An estrogen receptor alpha suppressor, microRNA-22, is downregulated in estrogen receptor alpha-positive human breast cancer cell lines and clinical samples. FEBS J 2010, 277:1684-1694. 10.1111/j.1742-4658.2010.07594.x, 20180843.
18. Li J, Liang S, Yu H, Zhang J, Ma D, Lu X. An inhibitory effect of miR-22 on cell migration and invasion in ovarian cancer. Gynecol Oncol 2010, 119:543-548. 10.1016/j.ygyno.2010.08.034, 20869762.
19. Yamakuchi M, Yagi S, Ito T, Lowenstein CJ. MicroRNA-22 regulates hypoxia signaling in colon cancer cells. PLoS One 2011, 6:e20291. 10.1371/journal.pone.0020291, 3100326, 21629773.
20. Ling B, Wang GX, Long G, Qiu JH, Hu ZL. Tumor suppressor miR-22 suppresses lung cancer cell progression through post-transcriptional regulation of ErbB3. J Cancer Res Clin Oncol 2012, 138:1355-1361. 10.1007/s00432-012-1194-2, 22484852.
21. Poliseno L, Salmena L, Riccardi L, Fornari A, Song MS, Hobbs RM, Sportoletti P, Varmeh S, Egia A, Fedele G, Rameh L, Loda M, Pandolfi PP. Identification of the miR-106b 25 microRNA cluster as a proto-oncogenic PTEN-targeting intron that cooperates with its host gene MCM7 in transformation. Sci Signal 2010, 3:ra29. 10.1126/scisignal.2000594, 2982149, 20388916.
22. Liu L, Jiang Y, Zhang H, Greenlee AR, Yu R, Yang Q. MiR-22 functions as a micro-oncogene in transformed human bronchial epithelial cells induced by anti-benzo[a]pyrene-7,8-diol-9,10-epoxide. Toxicol In Vitro 2010, 24:1168-1175. 10.1016/j.tiv.2010.02.016, 20170724.
23. Sobin LH, Wittekind C. TNM classification of malignant tumours 2002, 121-126. New York: Wiley, International Union Against Cancer, 6.
24. Gurha P, Abreu-Goodger C, Wang T, Ramirez MO, Drumond AL, van Dongen S, Chen Y, Bartonicek N, Enright AJ, Lee B, Kelm RJ, Reddy AK, Taffet GE, Bradley A, Wehrens XH, Entman ML, Rodriguez A. Targeted deletion of microRNA-22 promotes stress-induced cardiac dilation and contractile dysfunction. Circulation 2012, 125:2751-2761. 10.1161/CIRCULATIONAHA.111.044354, 3503489, 22570371.
25. Iliopoulos D, Malizos KN, Oikonomou P, Tsezou A. Integrative microRNA and proteomic approaches identify novel osteoarthritis genes and their collaborative metabolic and inflammatory networks. PLoS One 2008, 3:e3740. 10.1371/journal.pone.0003740, 2582945, 19011694.
26. Ting Y, Medina DJ, Strair RK, Schaar DG. Differentiation-associated miR-22 represses Max expression and inhibits cell cycle progression. Biochem Biophys Res Commun 2010, 394:606-611. 10.1016/j.bbrc.2010.03.030, 20214878.