Regulation of colorectal carcinoma Stemness, Growth, and metastasis by an miR-200c-Sox2-negative feedback loop mechanism

Clinical Cancer Research

Volumn 20, Issue 10, 2014, Pages 2631-2642

  Lu, Yan Xia ^a   Yuan, Li ^a   Xue, Xiao Lei ^a   Zhou, Min ^a   Liu, Yan ^a   Zhang, Chao ^a,b   Li, Jing Ping ^c   Zheng, Lin ^a   Hong, Min ^a   Li, Xue Nong ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

^c ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA 200C; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TRANSCRIPTION FACTOR SOX2; MICRORNA; MIRN200 MICRORNA, HUMAN; SOX2 PROTEIN, HUMAN; TRANSCRIPTION FACTOR SOX;

ANIMAL CELL; ARTICLE; CANCER GROWTH; CANCER STEM CELL; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; COLORECTAL CANCER CELL LINE; COLORECTAL CARCINOMA; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; GENE REPRESSION; GENETIC REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; METASTASIS; MOUSE; NEGATIVE FEEDBACK; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; ANIMAL; BAGG ALBINO MOUSE; COLORECTAL TUMOR; FEEDBACK SYSTEM; GENE EXPRESSION REGULATION; GENETICS; HCT116 CELL LINE; HEK293 CELL LINE; HT 29 CELL LINE; METABOLISM; NUDE MOUSE; PATHOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE; TUMOR VOLUME; WESTERN BLOTTING; XENOGRAFT;

ANIMALS; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL PROLIFERATION; COLORECTAL NEOPLASMS; FEEDBACK, PHYSIOLOGICAL; GENE EXPRESSION REGULATION, NEOPLASTIC; HCT116 CELLS; HEK293 CELLS; HT29 CELLS; HUMANS; MICE, INBRED BALB C; MICE, NUDE; MICRORNAS; NEOPLASM METASTASIS; NEOPLASTIC STEM CELLS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SOXB1 TRANSCRIPTION FACTORS; TRANSPLANTATION, HETEROLOGOUS; TUMOR BURDEN;

EID: 84901018900     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-13-2348     Document Type: Article

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