-
1
-
-
1542574202
-
Gene Expression Analysis of Human Prostate Carcinoma during Hormonal Therapy Identifies Androgen-Responsive Genes and Mechanisms of Therapy Resistance
-
Holzbeierlein J, Lal P, LaTulippe E, Smith A, Satagopan J, Zhang L, et al. Gene expression analysis of human prostate carcinoma during hormonal therapy identifies androgen-responsive genes and mechanisms of therapy resistance. Am J Pathol 2004;164:217-27. (Pubitemid 38364606)
-
(2004)
American Journal of Pathology
, vol.164
, Issue.1
, pp. 217-227
-
-
Holzbeierlein, J.1
Lal, P.2
LaTulippe, E.3
Smith, A.4
Satagopan, J.5
Zhang, L.6
Ryan, C.7
Smith, S.8
Scher, H.9
Scardino, P.10
Reuter, V.11
Gerald, W.L.12
-
2
-
-
2342558431
-
Androgen receptor in prostate cancer
-
DOI 10.1210/er.2002-0032
-
Heinlein CA, Chang C. Androgen receptor in prostate cancer. Endocr Rev 2004;25(2):276-308. (Pubitemid 38501396)
-
(2004)
Endocrine Reviews
, vol.25
, Issue.2
, pp. 276-308
-
-
Heinlein, C.A.1
Chang, C.2
-
3
-
-
51449087794
-
Targeting the androgen receptor pathway in prostate cancer
-
Chen Y, Sawyers CL, Scher HI. Targeting the androgen receptor pathway in prostate cancer. Curr Opin Pharmacol 2008;8:440-8.
-
(2008)
Curr Opin Pharmacol
, vol.8
, pp. 440-448
-
-
Chen, Y.1
Sawyers, C.L.2
Scher, H.I.3
-
4
-
-
0035496220
-
The development of androgen-independent prostate cancer
-
Feldman BJ, Feldman D. The development of androgen-independent prostate cancer. Nat Rev Cancer 2001;1:34-45. (Pubitemid 33741879)
-
(2001)
Nature Reviews Cancer
, vol.1
, Issue.1
, pp. 34-45
-
-
Feldman, B.J.1
Feldman, D.2
-
5
-
-
0029072101
-
Distant metastases from prostatic carcinoma express androgen receptor protein
-
Hobisch A, Culig Z, Radmayr C, Bartsch G, Klocker H, Hittmair A. Distant metastases from prostatic carcinoma express androgen receptor protein. Cancer Res 1995;55:3068-72.
-
(1995)
Cancer Res
, vol.55
, pp. 3068-3072
-
-
Hobisch, A.1
Culig, Z.2
Radmayr, C.3
Bartsch, G.4
Klocker, H.5
Hittmair, A.6
-
6
-
-
1842612441
-
Molecular determinants of resistance to antiandrogen therapy
-
DOI 10.1038/nm972
-
Chen CD, Welsbie DS, Tran C, Baek SH, Chen R, Vessella R, Rosenfeld MG, et al. Molecular determinants of resistance to antiandrogen therapy. Nat Med 2004;10:33-9. (Pubitemid 38524696)
-
(2004)
Nature Medicine
, vol.10
, Issue.1
, pp. 33-39
-
-
Chen, C.D.1
Welsbie, D.S.2
Tran, C.3
Baek, S.H.4
Chen, R.5
Vessella, R.6
Rosenfeld, M.G.7
Sawyers, C.L.8
-
7
-
-
77952103123
-
An integrated network of androgen receptor, polycomb, and TMPRSS2-ERG gene fusions in prostate cancer progression
-
Yu J, Yu J, Mani RS, Cao Q, Brenner CJ, Cao X, et al. An integrated network of androgen receptor, polycomb, and TMPRSS2-ERG gene fusions in prostate cancer progression. Cancer Cell 2010;17:443-54.
-
(2010)
Cancer Cell
, vol.17
, pp. 443-454
-
-
Yu, J.1
Yu, J.2
Mani, R.S.3
Cao, Q.4
Brenner, C.J.5
Cao, X.6
-
8
-
-
67650758019
-
Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer
-
Wang Q, Li W, Zhang Y, Yuan X, Xu K, Yu J, et al. Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer. Cell 2009;138:245-56.
-
(2009)
Cell
, vol.138
, pp. 245-256
-
-
Wang, Q.1
Li, W.2
Zhang, Y.3
Yuan, X.4
Xu, K.5
Yu, J.6
-
9
-
-
3042767202
-
MicroRNAs: Small RNAs with a big role in gene regulation
-
DOI 10.1038/nrg1379
-
He L, Hannon GJ. MicroRNAs: small RNAs with a big role in gene regulation. Nat Rev Genet 2004;5:522-31. (Pubitemid 38868508)
-
(2004)
Nature Reviews Genetics
, vol.5
, Issue.7
, pp. 522-531
-
-
He, L.1
Hannon, G.J.2
-
10
-
-
58249088751
-
MicroRNAs: Target recognition and regulatory functions
-
Bartel DP. MicroRNAs: target recognition and regulatory functions. Cell 2009;136:215-33.
-
(2009)
Cell
, vol.136
, pp. 215-233
-
-
Bartel, D.P.1
-
12
-
-
33645294070
-
Oncomirs - MicroRNAs with a role in cancer
-
Esquela-Kerscher A, Slack FJ. Oncomirs - microRNAs with a role in cancer. Nat Rev Cancer 2006;6:259-69.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 259-269
-
-
Esquela-Kerscher, A.1
Slack, F.J.2
-
13
-
-
33750370444
-
MicroRNA signatures in human cancers
-
DOI 10.1038/nrc1997, PII NRC1997
-
Calin GA, Croce CM. MicroRNA signatures in human cancers. Nat Rev Cancer 2006;6:857-66. (Pubitemid 44629897)
-
(2006)
Nature Reviews Cancer
, vol.6
, Issue.11
, pp. 857-866
-
-
Calin, G.A.1
Croce, C.M.2
-
14
-
-
77952918274
-
Genetic variation in microRNA networks: The implications for cancer research
-
Ryan BM, Robles AI, Harris CC. Genetic variation in microRNA networks: the implications for cancer research. Nat Rev Cancer 2010;10(6):389-402.
-
(2010)
Nat Rev Cancer
, vol.10
, Issue.6
, pp. 389-402
-
-
Ryan, B.M.1
Robles, A.I.2
Harris, C.C.3
-
15
-
-
73349125465
-
MicroRNAs in cancer: Small molecules with a huge impact
-
Iorio MV, Croce CM. MicroRNAs in cancer: small molecules with a huge impact. J Clin Oncol 2009;27:5848-56.
-
(2009)
J Clin Oncol
, vol.27
, pp. 5848-5856
-
-
Iorio, M.V.1
Croce, C.M.2
-
16
-
-
70049085160
-
Towards the definition of prostate cancer-related microRNAs: Where are we now?
-
Gandellini P, Folini M, Zaffaroni N. Towards the definition of prostate cancer-related microRNAs: where are we now?Trends Mol Med 2009;15:381-90.
-
(2009)
Trends Mol Med
, vol.15
, pp. 381-390
-
-
Gandellini, P.1
Folini, M.2
Zaffaroni, N.3
-
17
-
-
78249234164
-
miR-34c is down regulated in prostate cancer and exerts tumor suppressive functions
-
Hagman Z, Larne O, Edsjo A, Bjartell A, Ehrnström RA, Ulmert D, et al. miR-34c is down regulated in prostate cancer and exerts tumor suppressive functions. Int J Cancer 2010;127:2768-76.
-
(2010)
Int J Cancer
, vol.127
, pp. 2768-2776
-
-
Hagman, Z.1
Larne, O.2
Edsjo, A.3
Bjartell, A.4
Ehrnström, R.A.5
Ulmert, D.6
-
18
-
-
70449124423
-
Protein lysatemicroarray analysis to identify microRNAs regulating estrogen receptor signaling in breast cancer cell lines
-
Leivonen SK, Makela R, Ostling P, Kohonen P, Haapa-Paananen S, Kleivi K, et al. Protein lysatemicroarray analysis to identify microRNAs regulating estrogen receptor signaling in breast cancer cell lines. Oncogene 2009;28:3926-36.
-
(2009)
Oncogene
, vol.28
, pp. 3926-3936
-
-
Leivonen, S.K.1
Makela, R.2
Ostling, P.3
Kohonen, P.4
Haapa-Paananen, S.5
Kleivi, K.6
-
20
-
-
33751006151
-
RankProd: A bioconductor package for detecting differentially expressed genes in meta-analysis
-
DOI 10.1093/bioinformatics/btl476
-
Hong F, Breitling R, McEntee CW, Wittner BS, Nemhauser JL, Chory J. RankProd: a bioconductor package for detecting differentially expressed genes in meta-analysis. Bioinformatics 2006;22:2825-7. (Pubitemid 44742407)
-
(2006)
Bioinformatics
, vol.22
, Issue.22
, pp. 2825-2827
-
-
Hong, F.1
Breitling, R.2
McEntee, C.W.3
Wittner, B.S.4
Nemhauser, J.L.5
Chory, J.6
-
21
-
-
79952212387
-
GenomeGraphs: Integrated genomic data visualization with R
-
Durinck S, Bullard J, Spellman PT, Dudoit S. GenomeGraphs: integrated genomic data visualization with R. BMC Bioinformatics 2009;6(10):1-9.
-
(2009)
BMC Bioinformatics
, vol.6
, Issue.10
, pp. 1-9
-
-
Durinck, S.1
Bullard, J.2
Spellman, P.T.3
Dudoit, S.4
-
22
-
-
11244346557
-
Variance stabilization applied to microarray data calibration and to the quantification of differential expression
-
Huber W, von Heydebreck A, Sultmann H, Poustka A, Vingron M. Variance stabilization applied to microarray data calibration and to the quantification of differential expression. Bioinformatics 2002;18Suppl 1:S96-104.
-
(2002)
Bioinformatics
, Issue.18 SUPPL. 1
-
-
Huber, W.1
Von Heydebreck, A.2
Sultmann, H.3
Poustka, A.4
Vingron, M.5
-
23
-
-
38549124383
-
The microRNA.org resource: Targets and expression
-
Betel D, Wilson M, Gabow A, Marks DS, Sander C. The microRNA.org resource: targets and expression. Nucleic Acids Res 2008;36:D149-53.
-
(2008)
Nucleic Acids Res
, vol.36
-
-
Betel, D.1
Wilson, M.2
Gabow, A.3
Marks, D.S.4
Sander, C.5
-
24
-
-
0023922485
-
Cloning, structure and expression of a cDNA encoding the human androgen receptor
-
Trapman J, Klaassen P, Kuiper GG, van der Korput JA, Faber PW, van Rooij HC, et al. Cloning, structure and expression of a cDNA encoding the human androgen receptor. Biochem Biophys Res Commun 1988;153:241-8.
-
(1988)
Biochem Biophys Res Commun
, vol.153
, pp. 241-248
-
-
Trapman, J.1
Klaassen, P.2
Kuiper, G.G.3
Van Der Korput, J.A.4
Faber, P.W.5
Van Rooij, H.C.6
-
25
-
-
0024205612
-
The human androgen receptor: Complementary deoxyribonucleic acid cloning, sequence analysis and gene expression in prostate
-
Lubahn DB, Joseph DR, Sar M, Tan J, Higgs HN, Larson RE, et al. The human androgen receptor: complementary deoxyribonucleic acid cloning, sequence analysis and gene expression in prostate. Mol Endocrinol 1988;2:1265-75. (Pubitemid 19005939)
-
(1988)
Molecular Endocrinology
, vol.2
, Issue.12
, pp. 1265-1275
-
-
Lubahn, D.B.1
Joseph, D.R.2
Sar, M.3
Tan, J.4
Higgs, H.N.5
Larson, R.E.6
French, F.S.7
Wilson, E.M.8
-
26
-
-
0035064109
-
VCaP, a cell-based model system of human prostate cancer
-
Korenchuck S, Lehr JE, MClean L, Lee YG, Whitney S, Vessella R, et al. VCaP, a cell-based model system of human prostate cancer. In Vivo 2001;(15):163-63
-
(2001)
In Vivo
, Issue.15
, pp. 163-163
-
-
Korenchuck, S.1
Lehr, J.E.2
Mclean, L.3
Lee, Y.G.4
Whitney, S.5
Vessella, R.6
-
27
-
-
79952223637
-
Androgen receptor amplification is reflected in the transcriptional responses of Vertebral-Cancer of the Prostate cells
-
in press doi:10.1016
-
Makkonen H, Kauhanen M, Jääskeläinen T, Palvimo JJ. Androgen receptor amplification is reflected in the transcriptional responses of Vertebral-Cancer of the Prostate cells. Mol Cell Endocrinol 2010; in press doi:10.1016
-
(2010)
Mol Cell Endocrinol
-
-
Makkonen, H.1
Kauhanen, M.2
Jääskeläinen, T.3
Palvimo, J.J.4
-
28
-
-
65549168746
-
A novel androgen receptor splice variant is up-regulated during prostate cancer progression and promotes androgen depletion-resistant growth
-
Guo Z, Yang X, Sun F, Jiang R, Linn DE, Chen H, et al. A novel androgen receptor splice variant is up-regulated during prostate cancer progression and promotes androgen depletion-resistant growth. Cancer Res 2009;69:2305-13.
-
(2009)
Cancer Res
, vol.69
, pp. 2305-2313
-
-
Guo, Z.1
Yang, X.2
Sun, F.3
Jiang, R.4
Linn, D.E.5
Chen, H.6
-
29
-
-
48549089747
-
Splicing of a novel androgen receptor exon generates a constitutively active androgen receptor that mediates prostate cancer therapy resistance
-
Dehm SM, Schmidt LJ, Heemers HV, Vessella RL, Tindall DJ. Splicing of a novel androgen receptor exon generates a constitutively active androgen receptor that mediates prostate cancer therapy resistance. Cancer Res 2008;68:5469-77.
-
(2008)
Cancer Res
, vol.68
, pp. 5469-5477
-
-
Dehm, S.M.1
Schmidt, L.J.2
Heemers, H.V.3
Vessella, R.L.4
Tindall, D.J.5
-
31
-
-
79959703562
-
miR 488* inhibits androgen receptor expression in prostate carcinoma cells
-
in press, doi 10.1002/ijc.25753
-
Sikand K, Slaibi JE, Singh R, Slane SD, Shukla GC. miR 488* inhibits androgen receptor expression in prostate carcinoma cells. Int J Cancer 2010, in press, doi 10.1002/ijc.25753
-
(2010)
Int J Cancer
-
-
Sikand, K.1
Slaibi, J.E.2
Singh, R.3
Slane, S.D.4
Shukla, G.C.5
-
32
-
-
77954664186
-
A viral microRNA down-regulates multiple cell cycle genes through mRNA 5′UTRs
-
Grey F, Tirabassi R, Meyers H, Wu G, McWeeney S, Hook L, et al. A viral microRNA down-regulates multiple cell cycle genes through mRNA 5′UTRs. PLoS Pathog 2010;6:e1000967.1-9.
-
(2010)
PLoS Pathog
, vol.6
-
-
Grey, F.1
Tirabassi, R.2
Meyers, H.3
Wu, G.4
McWeeney, S.5
Hook, L.6
-
34
-
-
43449090367
-
MicroRNA-10a Binds the 5′UTR of Ribosomal Protein mRNAs and Enhances Their Translation
-
DOI 10.1016/j.molcel.2008.05.001, PII S1097276508003286
-
Orom UA, Nielsen FC, Lund AH. MicroRNA-10a binds the 5′UTR of ribosomal protein mRNAs and enhances their translation. Mol Cell 2008;30:460-71. (Pubitemid 351672378)
-
(2008)
Molecular Cell
, vol.30
, Issue.4
, pp. 460-471
-
-
Orom, U.A.1
Nielsen, F.C.2
Lund, A.H.3
-
35
-
-
67650087599
-
New class of microRNA targets containing simultaneous 5′-UTR and 3′-UTR interaction sites
-
Lee I, Ajay SS, Yook JI, Kim HS, Hong SH, Kim NH, et al. New class of microRNA targets containing simultaneous 5′-UTR and 3′-UTR interaction sites. Genome Res 2009;19:1175-83.
-
(2009)
Genome Res
, vol.19
, pp. 1175-1183
-
-
Lee, I.1
Ajay, S.S.2
Yook, J.I.3
Kim, H.S.4
Hong, S.H.5
Kim, N.H.6
-
36
-
-
74249123376
-
miR-145 participates with TP53 in a death-promoting regulatory loop and targets estrogen receptor-alpha in human breast cancer cells
-
Spizzo R, Nicoloso MS, Lupini L, et al. miR-145 participates with TP53 in a death-promoting regulatory loop and targets estrogen receptor-alpha in human breast cancer cells. Cell Death Differ 2010;17:246-54.
-
(2010)
Cell Death Differ
, vol.17
, pp. 246-254
-
-
Spizzo, R.1
Nicoloso, M.S.2
Lupini, L.3
-
37
-
-
77954847055
-
The landscape of C. elegans 3′UTRs
-
Mangone M, Manoharan AP, Thierry-Mieg D, Thierry-Mieg J, Han T, Mackowiak SD, et al. The landscape of C. elegans 3′UTRs. Science 2010;329:432-5.
-
(2010)
Science
, vol.329
, pp. 432-435
-
-
Mangone, M.1
Manoharan, A.P.2
Thierry-Mieg, D.3
Thierry-Mieg, J.4
Han, T.5
Mackowiak, S.D.6
-
38
-
-
77951092028
-
Multiple microRNAs modulate p21Cip1/Waf1 expression by directly targeting its 3′ untranslated region
-
Wu S, Huang S, Ding J, Zhao Y, Liang L, Liu T, et al. Multiple microRNAs modulate p21Cip1/Waf1 expression by directly targeting its 3′ untranslated region. Oncogene 2010;29:2302-8.
-
(2010)
Oncogene
, vol.29
, pp. 2302-2308
-
-
Wu, S.1
Huang, S.2
Ding, J.3
Zhao, Y.4
Liang, L.5
Liu, T.6
-
39
-
-
74249123570
-
The miR-34 family in cancer and apoptosis
-
Hermeking H. The miR-34 family in cancer and apoptosis. Cell Death Differ 2010;17:193-9.
-
(2010)
Cell Death Differ
, vol.17
, pp. 193-199
-
-
Hermeking, H.1
-
40
-
-
35748961986
-
p53 enters the microRNA world
-
Hermeking H. p53 enters the microRNA world. Cancer Cell 2007;12:414-8.
-
(2007)
Cancer Cell
, vol.12
, pp. 414-418
-
-
Hermeking, H.1
-
42
-
-
77951523950
-
Phase I clinical trial of the CYP17 inhibitor abiraterone acetate demonstrating clinical activity in patients with castration-resistant prostate cancer who received prior ketoconazole therapy
-
Ryan CJ, Smith MR, Fong L, Rosenberg JE, Kantoff P, Raynaud F, et al. Phase I clinical trial of the CYP17 inhibitor abiraterone acetate demonstrating clinical activity in patients with castration-resistant prostate cancer who received prior ketoconazole therapy. J Clin Oncol 2010;28:1481-8.
-
(2010)
J Clin Oncol
, vol.28
, pp. 1481-1488
-
-
Ryan, C.J.1
Smith, M.R.2
Fong, L.3
Rosenberg, J.E.4
Kantoff, P.5
Raynaud, F.6
-
43
-
-
77951518711
-
Significant and sustained antitumor activity in post-docetaxel, castration-resistant prostate cancer with the CYP17 inhibitor abiraterone acetate
-
Reid AH, Attard G, Danila DC, Oommen NB, Olmos D, Fong PC , et al. Significant and sustained antitumor activity in post-docetaxel, castration-resistant prostate cancer with the CYP17 inhibitor abiraterone acetate. J Clin Oncol 2010;28:1489-95.
-
(2010)
J Clin Oncol
, vol.28
, pp. 1489-1495
-
-
Reid, A.H.1
Attard, G.2
Danila, D.C.3
Oommen, N.B.4
Olmos, D.5
Fong, P.C.6
-
44
-
-
65649090203
-
Development of a second-generation antiandrogen for treatment of advanced prostate cancer
-
Tran C, Ouk S, Clegg NJ, Chen Y, Watson PA, Arora V, et al. Development of a second-generation antiandrogen for treatment of advanced prostate cancer. Science 2009;324:787-90.
-
(2009)
Science
, vol.324
, pp. 787-790
-
-
Tran, C.1
Ouk, S.2
Clegg, N.J.3
Chen, Y.4
Watson, P.A.5
Arora, V.6
|