Identification and functional screening of microRNAs highly deregulated in colorectal cancer

Journal of Cellular and Molecular Medicine

Volumn 16, Issue 11, 2012, Pages 2655-2666

  Faltejskova, Petra ^a,b   Svoboda, Marek ^a,b   Srutova, Klara ^b   Mlcochova, Jitka ^b   Besse, Andrej ^a,b   Nekvindova, Jana ^c   Radova, Lenka ^d   Fabian, Pavel ^a   Slaba, Katerina ^a   Kiss, Igor ^a   Vyzula, Rostislav ^a   Slaby, Ondrej ^a,b  

^a MASARYK MEMORIAL CANCER INSTITUTE   (Czech Republic)

^b CENTRAL EUROPEAN INSTITUTE OF TECHNOLOGY   (Czech Republic)

^c UNIVERSITY HOSPITAL HRADEC KRALOVE   (Czech Republic)

^d PALACKÝ UNIVERSITY   (Czech Republic)

Author keywords

Apoptosis; Colorectal cancer; Expression profiling; MicroRNA; Migration

Indexed keywords

MICRORNA; MIRN135 MICRORNA, HUMAN; MIRN215 MICRORNA, HUMAN; MIRN375 MICRORNA, HUMAN; MIRN378 MICRORNA, HUMAN; MIRN422 MICRORNA, HUMAN;

ADULT; AGED; APOPTOSIS; ARTICLE; CELL CYCLE CHECKPOINT; CELL MOTION; COLORECTAL TUMOR; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; MALE; MIDDLE AGED; PATHOLOGY; REPRODUCIBILITY; TUMOR CELL LINE; TUMOR SUPPRESSOR GENE; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; APOPTOSIS; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL MOVEMENT; COLORECTAL NEOPLASMS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, TUMOR SUPPRESSOR; HUMANS; MALE; MICRORNAS; MIDDLE AGED; REPRODUCIBILITY OF RESULTS;

EID: 84868144684     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1582-4934.2012.01579.x     Document Type: Article

References (37)

1. Siegel R, Ward E, Brawley O, et al. Cancer statistics, 2011. CA Cancer J Clin. 2011; 61: 212-36.
2. Janga SC, Vallabhaneni S. MicroRNAs as post-transcriptional machines and their interplay with cellular networks. Adv Exp Med Biol. 2011; 722: 59-74.
3. Wang Y, Lee CG. MicroRNA and cancer - focus on apoptosis. J Cell Mol Med. 2009; 13: 12-23.
4. Slaby O, Svoboda M, Michalek J, et al. MicroRNAs in colorectal cancer: translation of molecular biology into clinical application. Mol Cancer. 2009; 8: 102.
5. Slaby O, Svoboda M, Fabian P, et al. Altered expression of miR-21, miR-31, miR-143 and miR-145 is related to clinicopathologic features of colorectal cancer. Oncology. 2007; 72: 397-402.
6. Schepeler T, Reinert JT, Ostenfeld MS, et al. Diagnostic and prognostic microRNAs in stage II colon cancer. Cancer Res. 2008; 68: 6416-24.
7. Sarver AL, French AJ, Borralho PM, et al. Human colon cancer profiles show differential microRNA expression depending on mismatch repair status and are characteristic of undifferentiated proliferative states. BMC Cancer. 2009; 9: 401.
8. Schetter AJ, Leung SY, Sohn JJ, et al. MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma. JAMA. 2008; 299: 425-36.
9. Bandrés E, Cubedo E, Agirre X, et al. Identification by real-time PCR of 13 mature microRNAs differentially expressed in colorectal cancer and non-tumoral tissues. Mol Cancer. 2006; 5: 29.
10. Earle JSL, Luthra R, Romans A, et al. Association of microRNA expression with microsatellite instability status in colorectal adenocarcinoma. J Mol Diagn. 2010; 12: 433-40.
11. Koga Y, Yasunaga M, Takahashi A, et al. MicroRNA expression profiling of exfoliated colonocytes isolated from feces for colorectal cancer screening. Cancer Prev Res. 2010; 3: 1435-42.
12. Díaz R, Silva J, García JM, et al. Deregulated expression of miR-106a predicts survival in human colon cancer patients. Genes Chromosom Cancer. 2008; 47: 794-802.
13. Ng EKO, Chong WWS, Jin H, et al. Differential expression of microRNAs in plasma of patients with colorectal cancer: a potential marker for colorectal cancer screening. Gut. 2009; 58: 1375-81.
14. Pu X-Xiang, Huang G-Liang, Guo H-Qiang, et al. Circulating miR-221 directly amplified from plasma is a potential diagnostic and prognostic marker of colorectal cancer and is correlated with p53 expression. J Gastroenterol Hepatol. 2010; 25: 1674-80.
15. Wang L-G, Gu J. Serum microRNA-29a is a promising novel marker for early detection of colorectal liver metastasis. Cancer Epidemiol. 2011; doi:10.1016/j.canep.2011.05.002.
16. Reimers M, Carey VJ. Bioconductor: an open source framework for bioinformatics and computational biology. Methods Enzymol. 2006; 411: 119-134.
17. Miko E, Czimmerer Z, Csánky E, et al. Differentially expressed microRNAs in small cell lung cancer. Exp Lung Res. 2009; 35: 646-64.
18. Hannafon BN, Sebastiani P, de las Morenas A, et al. Expression of microRNA and their gene targets are dysregulated in preinvasive breast cancer. Breast Cancer Res. 2011; 13: R24.
19. Schaefer A, Jung M, Mollenkopf H-J, et al. Diagnostic and prognostic implications of microRNA profiling in prostate carcinoma. Int J Cancer. 2010; 126: 1166-76.
20. Nagel R, le Sage C, Diosdado B, et al. Regulation of the adenomatous polyposis coli gene by the miR-135 family in colorectal cancer. Cancer Res. 2008; 68: 5795-802.
21. Chang KH, Miller N, Kheirelseid EAH, et al. MicroRNA signature analysis in colorectal cancer: identification of expression profiles in stage II tumors associated with aggressive disease. Int J Colorectal Dis. 2011; 26: 1415-22.
22. Paun BC, Cheng Y, Leggett BA, et al. Screening for microsatellite instability identifies frequent 3′-untranslated region mutation of the RB1-inducible coiled-coil 1 gene in colon tumors. PLoS One. 2009; 4: e7715.
23. Bitarte N, Bandres E, Boni V, et al. MicroRNA-451 is involved in the self-renewal, tumorigenicity, and chemoresistance of colorectal cancer stem cells. Stem Cells. 2011; 29: 1661-71.
24. Wang YX, Zhang XY, Zhang BF, et al. Initial study of microRNA expression profiles of colonic cancer without lymph node metastasis. J Dig Dis. 2010; 11: 50-4.
25. Kalimutho M, Del Vecchio Blanco G, Di Cecilia S, et al. Differential expression of miR-144* as a novel fecal-based diagnostic marker for colorectal cancer. J Gastroenterol. 2011; 46: 1391-402.
26. Liu L, Chen L, Xu Y, et al. MicroRNA-195 promotes apoptosis and suppresses tumorigenicity of human colorectal cancer cells. Biochem Biophys Res Commun. 2010; 400: 236-40.
27. Sundaram P, Hultine S, Smith LM, et al. p53-responsive miR-194 inhibits thrombospondin-1 and promotes angiogenesis in colon cancers. Cancer Res. 2011; 71:7490-501.
28. Xi Y, Formentini A, Chien M, et al. Prognostic values of microRNAs in colorectal cancer. Biomark Insights. 2006; 2: 113-21.
29. Strillacci A, Griffoni C, Sansone P, et al. MiR-101 downregulation is involved in cyclooxygenase-2 overexpression in human colon cancer cells. Exp Cell Res. 2009; 315: 1439-47.
30. Michael MZ, O' Connor SM, van Holst Pellekaan NG, et al. Reduced accumulation of specific microRNAs in colorectal neoplasia. Mol Cancer Res. 2003; 1: 882-91.
31. Cho WCS, Chow ASC, Au JSK. MiR-145 inhibits cell proliferation of human lung adenocarcinoma by targeting EGFR and NUDT1. RNA Biol. 2011; 8: 125-31.
32. Sachdeva M, Mo Y-Y. miR-145-mediated suppression of cell growth, invasion and metastasis. Am J Transl Res. 2010; 2:170-80.
33. Boominathan L. The guardians of the genome (p53, TA-p73, and TA-p63) are regulators of tumor suppressor miRNAs network. Cancer Metastasis Rev. 2010; 29: 613-39.
34. Braun CJ, Zhang X, Savelyeva I, et al. p53-responsive microRNAs 192 and 215 are capable of inducing cell cycle arrest. Cancer Res. 2008; 68:10094-104.
35. Karaayvaz M, Pal T, Song B, et al. Prognostic significance of miR-215 in colon cancer. Clin Colorectal Cancer. 2011; 10: 340-7.
36. Necela BM, Carr JM, Asmann YW, Thompson EA. Differential expression of microRNAs in tumours from chronically inflamed or genetic (APC(Min/+)) models of colon cancer. PLoS One. 2011; 6: e18501.
37. Tsukamoto Y, Nakada C, Noguchi T, et al. MicroRNA-375 is downregulated in gastric carcinomas and regulates cell survival by targeting PDK1 and 14-3-3zeta. Cancer Res. 2010; 70: 2339-49.