Loss of miRNA biogenesis induces p19Arf-p53 signaling and senescence in primary cells

Journal of Cell Biology

Volumn 181, Issue 7, 2008, Pages 1055-1063

  Mudhasani, Rajini ^a   Zhu, Zhiqing ^a   Hutvagner, Gyorgy ^a   Eischen, Christine M ^b   Lyle, Stephen ^a   Hall, Lisa L ^a   Lawrence, Jeanne B ^a   Imbalzano, Anthony N ^a   Jones, Stephen N ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2A; DICER; MICRORNA; MYC PROTEIN; PROTEIN P53; RAS PROTEIN;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIOGENESIS; CELL AGING; CELL GROWTH; CELL MATURATION; CELL PROLIFERATION; CONTROLLED STUDY; DNA DAMAGE; EMBRYO; EMBRYONIC STEM CELL; FIBROBLAST; GENE DELETION; GENE INDUCTION; GENE LOCUS; GENE TARGETING; IN VIVO STUDY; LIMB DEVELOPMENT; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SKIN; UPREGULATION;

ANIMALS; CELL AGING; CELL PROLIFERATION; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DNA DAMAGE; EMBRYO, MAMMALIAN; FIBROBLASTS; GENE DELETION; MICE; MICRORNAS; RIBONUCLEASE III; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

MAMMALIA; MUS;

EID: 46249107572     PISSN: 00219525     EISSN: 00219525     Source Type: Journal    
DOI: 10.1083/jcb.200802105     Document Type: Article

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