Analysis of the combined action of miR-143 and miR-145 on oncogenic pathways in colorectal cancer cells reveals a coordinate program of gene repression

Oncogene

Volumn 32, Issue 40, 2013, Pages 4806-4813

  Pagliuca, A ^a   Valvo, C ^b   Fabrizi, E ^a   Di Martino, S ^a,b   Biffoni, M ^a   Runci, D ^a   Forte, S ^c   De Maria, R ^b   Ricci Vitiani, L ^a  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^b REGINA ELENA NATIONAL CANCER INSTITUTE   (Italy)

^c IOM Ricerca srl   (Italy)

Author keywords

colorectal cancer; microarray; miRNA; RAS MAPK; signaling pathway

Indexed keywords

B RAF KINASE; FLUOROURACIL; HERMES ANTIGEN; IRINOTECAN; K RAS PROTEIN; KRUPPEL LIKE FACTOR 5; MESSENGER RNA; MICRORNA 143; MICRORNA 145; MITOGEN ACTIVATED PROTEIN KINASE; OXALIPLATIN; PROTEIN P53;

3' UNTRANSLATED REGION; ANCHORAGE INDEPENDENT GROWTH; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CARCINOGENESIS; CARCINOGENICITY; CELL CYCLE PROGRESSION; CELL CYCLE REGULATION; CELL MIGRATION; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; CHEMOSENSITIVITY; COLON MUCOSA; COLORECTAL CANCER; CONTROLLED STUDY; DOWN REGULATION; GENE CLUSTER; GENE OVEREXPRESSION; GENE REPRESSION; GENETIC ANALYSIS; HYPOTHESIS; IN VITRO STUDY; IN VIVO STUDY; KIRSTEN SARCOMA ONCOVIRUS; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PHENOTYPE; PLEIOTROPY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TUMOR XENOGRAFT; VIRUS ONCOGENE;

ANIMALS; CELL DIVISION; CELL LINE, TUMOR; COLORECTAL NEOPLASMS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE REGULATORY NETWORKS; HUMANS; MICE; MICRORNAS; ONCOGENES; REAL-TIME POLYMERASE CHAIN REACTION; TRANSCRIPTOME; XENOGRAFT MODEL ANTITUMOR ASSAYS;

MURINAE; RATTUS;

EID: 84885186640     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2012.495     Document Type: Article

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