메뉴 건너뛰기




Volumn 14, Issue 7, 2014, Pages 909-931

Cardiovascular pharmacogenetics of anti-thrombotic agents and non-steroidal anti-inflammatory drugs

Author keywords

Antiplatelet; Antithrombotic; Aspirin; Cyclooxygenase 1 and 2 (COX 1 and COX 2); Non steroidal anti inflammatory drugs (NSAIDs); Pharmacogenetics; Pharmacogenomics

Indexed keywords

ABC TRANSPORTER; ACETYLSALICYLIC ACID; ADENOSINE DIPHOSPHATE; ANTICOAGULANT AGENT; ANTITHROMBOCYTIC AGENT; BETA3 INTEGRIN; BIOLOGICAL MARKER; CALCIUM; CELECOXIB; CHOLESTEROL; CLOPIDOGREL; CREATINE KINASE MB; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; CYTOCHROME P450 2C19; ETORICOXIB; FAT; FIBRIN; FIBRINOGEN RECEPTOR ANTAGONIST; G PROTEIN COUPLED RECEPTOR; GLYCOPROTEIN IIIA; IBUPROFEN; MULTIDRUG RESISTANCE PROTEIN 1; NAPROXEN; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTACYCLIN RECEPTOR; PURINERGIC P2Y12 RECEPTOR; ROFECOXIB; THROMBIN; THROMBOXANE A2; TROPONIN I; UNINDEXED DRUG; VALDECOXIB; ABCIXIMAB; CARDIOVASCULAR AGENT; DICLOFENAC; EPTIFIBATIDE; INTEGRIN; LUMIRACOXIB; METOPROLOL; OMEPRAZOLE; THROMBOCYTE ANTIGEN; TIROFIBAN; FIBRINOLYTIC AGENT;

EID: 84906912678     PISSN: 15665240     EISSN: 18755666     Source Type: Journal    
DOI: 10.2174/1566524014666140811121109     Document Type: Article
Times cited : (5)

References (242)
  • 1
    • 84872091789 scopus 로고    scopus 로고
    • Heart disease and stroke statistics--2013 update: A report from the American Heart Association
    • Go AS, Mozaffarian D, Roger VL, et al. Heart disease and stroke statistics--2013 update: a report from the American Heart Association. Circulation 2013; 127(1): e6-e245.
    • (2013) Circulation , vol.127 , Issue.1
    • Go, A.S.1    Mozaffarian, D.2    Roger, V.L.3
  • 2
    • 84872054233 scopus 로고    scopus 로고
    • Executive summary: Heart disease and stroke statistics--2013 update: A report from the American Heart Association
    • Go AS, Mozaffarian D, Roger VL, et al. Executive summary: heart disease and stroke statistics--2013 update: a report from the American Heart Association. Circulation 2013; 127(1): 143-52.
    • (2013) Circulation , vol.127 , Issue.1 , pp. 143-152
    • Go, A.S.1    Mozaffarian, D.2    Roger, V.L.3
  • 4
    • 77955638355 scopus 로고    scopus 로고
    • ACCF/AHA clopidogrel clinical alert: Approaches to the FDA "boxed warning": A report of the American College of Cardiology Foundation Task Force on clinical expert consensus documents and the American Heart Association endorsed by the Society for Cardiovascular Angiography and Interventions and the Society of Thoracic Surgeons
    • Holmes DR, Jr., Dehmer GJ, Kaul S, Leifer D, O'Gara PT, Stein CM. ACCF/AHA clopidogrel clinical alert: approaches to the FDA "boxed warning": a report of the American College of Cardiology Foundation Task Force on clinical expert consensus documents and the American Heart Association endorsed by the Society for Cardiovascular Angiography and Interventions and the Society of Thoracic Surgeons. J Am Coll Cardiol 2010; 56(4): 321-41.
    • (2010) J Am Coll Cardiol , vol.56 , Issue.4 , pp. 321-341
    • Holmes Jr., D.R.1    Dehmer, G.J.2    Kaul, S.3    Leifer, D.4    O'Gara, P.T.5    Stein, C.M.6
  • 5
    • 84872728410 scopus 로고    scopus 로고
    • Drug resistance and pseudoresistance: An unintended consequence of enteric coating aspirin
    • Grosser T, Fries S, Lawson JA, Kapoor SC, Grant GR, FitzGerald GA. Drug resistance and pseudoresistance: an unintended consequence of enteric coating aspirin. Circulation 2013; 127(3): 377-85.
    • (2013) Circulation , vol.127 , Issue.3 , pp. 377-385
    • Grosser, T.1    Fries, S.2    Lawson, J.A.3    Kapoor, S.C.4    Grant, G.R.5    FitzGerald, G.A.6
  • 6
    • 32844458145 scopus 로고    scopus 로고
    • Aspirin resistance
    • Hankey GJ, Eikelboom JW. Aspirin resistance. Lancet 2006; 367(9510): 606-17.
    • (2006) Lancet , vol.367 , Issue.9510 , pp. 606-617
    • Hankey, G.J.1    Eikelboom, J.W.2
  • 7
    • 38949119325 scopus 로고    scopus 로고
    • Aspirin "resistance" and risk of cardiovascular morbidity: Systematic review and meta-analysis
    • Krasopoulos G, Brister SJ, Beattie WS, Buchanan MR. Aspirin "resistance" and risk of cardiovascular morbidity: systematic review and meta-analysis. BMJ 2008; 336(7637): 195-8.
    • (2008) BMJ , vol.336 , Issue.7637 , pp. 195-198
    • Krasopoulos, G.1    Brister, S.J.2    Beattie, W.S.3    Buchanan, M.R.4
  • 8
    • 84863266046 scopus 로고    scopus 로고
    • Aspirin resistance: Clinical significance and genetic polymorphism
    • Xu ZH, Jiao JR, Yang R, Luo BY, Wang XF, Wu F. Aspirin resistance: clinical significance and genetic polymorphism. J Int Med Res. 2012; 40(1): 282-92.
    • (2012) J Int Med Res. , vol.40 , Issue.1 , pp. 282-292
    • Xu, Z.H.1    Jiao, J.R.2    Yang, R.3    Luo, B.Y.4    Wang, X.F.5    Wu, F.6
  • 9
    • 17144407991 scopus 로고    scopus 로고
    • Pharmacodynamic interaction of naproxen with low-dose aspirin in healthy subjects
    • Capone ML, Sciulli MG, Tacconelli S, et al. Pharmacodynamic interaction of naproxen with low-dose aspirin in healthy subjects. J Am Coll Cardiol 2005; 45(8): 1295-301.
    • (2005) J Am Coll Cardiol , vol.45 , Issue.8 , pp. 1295-1301
    • Capone, M.L.1    Sciulli, M.G.2    Tacconelli, S.3
  • 10
    • 84877011402 scopus 로고    scopus 로고
    • High on treatment platelet reactivity against aspirin by non-steroidal anti-inflammatory drugs--pharmacological mechanisms and clinical relevance
    • Hohlfeld T, Saxena A, Schror K. High on treatment platelet reactivity against aspirin by non-steroidal anti-inflammatory drugs--pharmacological mechanisms and clinical relevance. Thromb Haemost 2013; 109(5): 825-33.
    • (2013) Thromb Haemost , vol.109 , Issue.5 , pp. 825-833
    • Hohlfeld, T.1    Saxena, A.2    Schror, K.3
  • 11
    • 0035924765 scopus 로고    scopus 로고
    • Cyclooxygenase inhibitors and the antiplatelet effects of aspirin
    • Catella-Lawson F, Reilly MP, Kapoor SC, et al. Cyclooxygenase inhibitors and the antiplatelet effects of aspirin. N Engl J Med 2001; 345(25): 1809-17.
    • (2001) N Engl J Med , vol.345 , Issue.25 , pp. 1809-1817
    • Catella-Lawson, F.1    Reilly, M.P.2    Kapoor, S.C.3
  • 12
    • 34249827579 scopus 로고    scopus 로고
    • Cardiovascular outcomes in high risk patients with osteoarthritis treated with ibuprofen, naproxen or lumiracoxib
    • Farkouh ME, Greenberg JD, Jeger RV, et al. Cardiovascular outcomes in high risk patients with osteoarthritis treated with ibuprofen, naproxen or lumiracoxib. Ann Rheum Dis 2007; 66(6): 764-70.
    • (2007) Ann Rheum Dis , vol.66 , Issue.6 , pp. 764-770
    • Farkouh, M.E.1    Greenberg, J.D.2    Jeger, R.V.3
  • 13
    • 78751695197 scopus 로고    scopus 로고
    • Cardiovascular safety of non-steroidal anti-inflammatory drugs: Network meta-analysis
    • Trelle S, Reichenbach S, Wandel S, et al. Cardiovascular safety of non-steroidal anti-inflammatory drugs: network meta-analysis. BMJ 2011; 342: c7086.
    • (2011) BMJ , vol.342
    • Trelle, S.1    Reichenbach, S.2    Wandel, S.3
  • 14
    • 79958120454 scopus 로고    scopus 로고
    • Duration of treatment with nonsteroidal anti-inflammatory drugs and impact on risk of death and recurrent myocardial infarction in patients with prior myocardial infarction: A nationwide cohort study
    • Schjerning Olsen AM, Fosbol EL, Lindhardsen J, et al. Duration of treatment with nonsteroidal anti-inflammatory drugs and impact on risk of death and recurrent myocardial infarction in patients with prior myocardial infarction: a nationwide cohort study. Circulation 2011; 123(20): 2226-35.
    • (2011) Circulation , vol.123 , Issue.20 , pp. 2226-2235
    • Schjerning, O.A.M.1    Fosbol, E.L.2    Lindhardsen, J.3
  • 15
    • 84883134602 scopus 로고    scopus 로고
    • Vascular and upper gastrointestinal effects of non-steroidal anti-inflammatory drugs: Meta-analyses of individual participant data from randomised trials
    • Bhala N, Emberson J, Merhi A, et al. Vascular and upper gastrointestinal effects of non-steroidal anti-inflammatory drugs: meta-analyses of individual participant data from randomised trials. Lancet 2013; 382(9894): 769-79.
    • (2013) Lancet , vol.382 , Issue.9894 , pp. 769-779
    • Bhala, N.1    Emberson, J.2    Merhi, A.3
  • 16
    • 84860703445 scopus 로고    scopus 로고
    • Vascular COX-2 modulates blood pressure and thrombosis in mice
    • Yu Y, Ricciotti E, Scalia R, et al. Vascular COX-2 modulates blood pressure and thrombosis in mice. Sci Transl Med 2012; 4(132): 132ra54.
    • (2012) Sci Transl Med , vol.4 , Issue.132
    • Yu, Y.1    Ricciotti, E.2    Scalia, R.3
  • 17
    • 84855869465 scopus 로고    scopus 로고
    • Systemic and local factors associated with coronary plaque disruption
    • Ueda Y, Matsuo K, Nishio M, et al. Systemic and local factors associated with coronary plaque disruption. Thromb Res 2012; 129(2): 164-8.
    • (2012) Thromb Res , vol.129 , Issue.2 , pp. 164-168
    • Ueda, Y.1    Matsuo, K.2    Nishio, M.3
  • 18
    • 0029090411 scopus 로고
    • Coronary plaque disruption
    • Falk E, Shah PK, Fuster V. Coronary plaque disruption. Circulation 1995; 92(3): 657-71.
    • (1995) Circulation , vol.92 , Issue.3 , pp. 657-671
    • Falk, E.1    Shah, P.K.2    Fuster, V.3
  • 19
    • 84867362492 scopus 로고    scopus 로고
    • Third universal definition of myocardial infarction
    • Thygesen K, Alpert JS, Jaffe AS, et al. Third universal definition of myocardial infarction. J Am Coll Cardiol 2012; 60(16): 1581-98.
    • (2012) J Am Coll Cardiol , vol.60 , Issue.16 , pp. 1581-1598
    • Thygesen, K.1    Alpert, J.S.2    Jaffe, A.S.3
  • 20
    • 0027262650 scopus 로고
    • Cardiac troponin I. A marker with high specificity for cardiac injury
    • Adams JE, 3rd, Bodor GS, Davila-Roman VG, et al. Cardiac troponin I. A marker with high specificity for cardiac injury. Circulation 1993; 88(1): 101-6.
    • (1993) Circulation , vol.88 , Issue.1 , pp. 101-106
    • Adams III, J.E.1    Bodor, G.S.2    Davila-Roman, V.G.3
  • 21
    • 0041963115 scopus 로고    scopus 로고
    • Plasma 99th percentile reference limits for cardiac troponin and creatine kinase MB mass for use with European Society of Cardiology/American College of Cardiology consensus recommendations
    • Apple FS, Quist HE, Doyle PJ, Otto AP, Murakami MM. Plasma 99th percentile reference limits for cardiac troponin and creatine kinase MB mass for use with European Society of Cardiology/American College of Cardiology consensus recommendations. Clin Chem 2003; 49(8): 1331-6.
    • (2003) Clin Chem , vol.49 , Issue.8 , pp. 1331-1336
    • Apple, F.S.1    Quist, H.E.2    Doyle, P.J.3    Otto, A.P.4    Murakami, M.M.5
  • 22
    • 36249003906 scopus 로고    scopus 로고
    • Universal definition of myocardial infarction
    • Joint ESCAAHAWHFTFftRoM.I
    • Thygesen K, Alpert JS, White HD, Joint ESCAAHAWHFTFftRoMI. Universal definition of myocardial infarction. J Am Coll Cardiol 2007; 50(22): 2173-95.
    • (2007) J Am Coll Cardiol , vol.50 , Issue.22 , pp. 2173-2195
    • Thygesen, K.1    Alpert, J.S.2    White, H.D.3
  • 23
    • 0033851515 scopus 로고    scopus 로고
    • Myocardial infarction redefined--a consensus document of The Joint European Society of Cardiology/American College of Cardiology Committee for the redefinition of myocardial infarction
    • Alpert JS, Thygesen K, Antman E, Bassand JP. Myocardial infarction redefined--a consensus document of The Joint European Society of Cardiology/American College of Cardiology Committee for the redefinition of myocardial infarction. J Am Coll Cardiol 2000; 36(3): 959-69.
    • (2000) J Am Coll Cardiol , vol.36 , Issue.3 , pp. 959-969
    • Alpert, J.S.1    Thygesen, K.2    Antman, E.3    Bassand, J.P.4
  • 25
    • 67849126851 scopus 로고    scopus 로고
    • Dynamics of platelet thrombus formation
    • Jackson SP, Nesbitt WS, Westein E. Dynamics of platelet thrombus formation. J Thromb Haemost 2009; 7 Suppl 1: 17-20.
    • (2009) J Thromb Haemost , vol.7 , Issue.SUPPL. 1 , pp. 17-20
    • Jackson, S.P.1    Nesbitt, W.S.2    Westein, E.3
  • 27
    • 67149093849 scopus 로고    scopus 로고
    • A shear gradient-dependent platelet aggregation mechanism drives thrombus formation
    • Nesbitt WS, Westein E, Tovar-Lopez FJ, et al. A shear gradient-dependent platelet aggregation mechanism drives thrombus formation. Nat Med 2009; 15(6): 665-73.
    • (2009) Nat Med , vol.15 , Issue.6 , pp. 665-673
    • Nesbitt, W.S.1    Westein, E.2    Tovar-Lopez, F.J.3
  • 28
    • 33748704252 scopus 로고    scopus 로고
    • Activation-independent platelet adhesion and aggregation under elevated shear stress
    • Ruggeri ZM, Orje JN, Habermann R, Federici AB, Reininger AJ. Activation-independent platelet adhesion and aggregation under elevated shear stress. Blood 2006; 108(6): 1903-10.
    • (2006) Blood , vol.108 , Issue.6 , pp. 1903-1910
    • Ruggeri, Z.M.1    Orje, J.N.2    Habermann, R.3    Federici, A.B.4    Reininger, A.J.5
  • 29
    • 33846240313 scopus 로고    scopus 로고
    • Identification of a 2-stage platelet aggregation process mediating shear-dependent thrombus formation
    • Maxwell MJ, Westein E, Nesbitt WS, Giuliano S, Dopheide SM, Jackson SP. Identification of a 2-stage platelet aggregation process mediating shear-dependent thrombus formation. Blood 2007;109(2):566-76.
    • (2007) Blood , vol.109 , Issue.2 , pp. 566-576
    • Maxwell, M.J.1    Westein, E.2    Nesbitt, W.S.3    Giuliano, S.4    Dopheide, S.M.5    Jackson, S.P.6
  • 30
    • 33845606632 scopus 로고    scopus 로고
    • Activation of platelet function through G protein-coupled receptors
    • Offermanns S. Activation of platelet function through G protein-coupled receptors. Circ Res 2006; 99(12): 1293-304.
    • (2006) Circ Res , vol.99 , Issue.12 , pp. 1293-1304
    • Offermanns, S.1
  • 31
    • 81255143017 scopus 로고    scopus 로고
    • Arterial thrombosis--insidious, unpredictable and deadly
    • Jackson SP. Arterial thrombosis--insidious, unpredictable and deadly. Nat Med. 2011;17(11):1423-36.
    • (2011) Nat Med. , vol.17 , Issue.11 , pp. 1423-1436
    • Jackson, S.P.1
  • 32
    • 18144442646 scopus 로고    scopus 로고
    • Anticoagulants versus antiplatelet agents for acute ischaemic stroke
    • Berge E, Sandercock P. Anticoagulants versus antiplatelet agents for acute ischaemic stroke. Cochrane Database Syst Rev 2002(4): CD003242.
    • (2002) Cochrane Database Syst Rev , Issue.4
    • Berge, E.1    Sandercock, P.2
  • 33
    • 84873569160 scopus 로고    scopus 로고
    • Concomitant use of antiplatelet therapy with dabigatran or warfarin in the Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) trial
    • Dans AL, Connolly SJ, Wallentin L, et al. Concomitant use of antiplatelet therapy with dabigatran or warfarin in the Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) trial. Circulation 2013; 127(5): 634-40.
    • (2013) Circulation , vol.127 , Issue.5 , pp. 634-640
    • Dans, A.L.1    Connolly, S.J.2    Wallentin, L.3
  • 34
    • 84896117299 scopus 로고    scopus 로고
    • Comparison of the efficacy and safety of new oral anticoagulants with warfarin in patients with atrial fibrillation: A meta-analysis of randomised trials
    • Ruff CT, Giugliano RP, Braunwald E, et al. Comparison of the efficacy and safety of new oral anticoagulants with warfarin in patients with atrial fibrillation: a meta-analysis of randomised trials. Lancet 2014; 383(9921): 955-62.
    • (2014) Lancet , vol.383 , Issue.9921 , pp. 955-962
    • Ruff, C.T.1    Giugliano, R.P.2    Braunwald, E.3
  • 36
    • 0033606533 scopus 로고    scopus 로고
    • Low-dose and high-dose acetylsalicylic acid for patients undergoing carotid endarterectomy: A randomised controlled trial. ASA and Carotid Endarterectomy (ACE) Trial Collaborators
    • Taylor DW, Barnett HJ, Haynes RB, et al. Low-dose and high-dose acetylsalicylic acid for patients undergoing carotid endarterectomy: a randomised controlled trial. ASA and Carotid Endarterectomy (ACE) Trial Collaborators. Lancet 1999; 353(9171): 2179-84.
    • (1999) Lancet , vol.353 , Issue.9171 , pp. 2179-2184
    • Taylor, D.W.1    Barnett, H.J.2    Haynes, R.B.3
  • 37
    • 0033679411 scopus 로고    scopus 로고
    • Update on clinical trials of antiplatelet therapy for cerebrovascular diseases
    • Bhatt DL, Kapadia SR, Yadav JS, Topol EJ. Update on clinical trials of antiplatelet therapy for cerebrovascular diseases. Cerebrovasc Dis 2000; 10 Suppl 5: 34-40.
    • (2000) Cerebrovasc Dis , vol.10 , Issue.SUPPL. 5 , pp. 34-40
    • Bhatt, D.L.1    Kapadia, S.R.2    Yadav, J.S.3    Topol, E.J.4
  • 38
    • 0035850414 scopus 로고    scopus 로고
    • Aspirin use and all-cause mortality among patients being evaluated for known or suspected coronary artery disease: A propensity analysis
    • Gum PA, Thamilarasan M, Watanabe J, Blackstone EH, Lauer MS. Aspirin use and all-cause mortality among patients being evaluated for known or suspected coronary artery disease: A propensity analysis. JAMA 2001; 286(10): 1187-94.
    • (2001) JAMA , vol.286 , Issue.10 , pp. 1187-1194
    • Gum, P.A.1    Thamilarasan, M.2    Watanabe, J.3    Blackstone, E.H.4    Lauer, M.S.5
  • 39
    • 0345131724 scopus 로고    scopus 로고
    • Erythrocyte promotion of platelet reactivity decreases the effectiveness of aspirin as an antithrombotic therapeutic modality: The effect of low-dose aspirin is less than optimal in patients with vascular disease due to prothrombotic effects of erythrocytes on platelet reactivity
    • Valles J, Santos MT, Aznar J, et al. Erythrocyte promotion of platelet reactivity decreases the effectiveness of aspirin as an antithrombotic therapeutic modality: the effect of low-dose aspirin is less than optimal in patients with vascular disease due to prothrombotic effects of erythrocytes on platelet reactivity. Circulation 1998; 97(4): 350-5.
    • (1998) Circulation , vol.97 , Issue.4 , pp. 350-355
    • Valles, J.1    Santos, M.T.2    Aznar, J.3
  • 42
    • 0037454168 scopus 로고    scopus 로고
    • A prospective, blinded determination of the natural history of aspirin resistance among stable patients with cardiovascular disease
    • Gum PA, Kottke-Marchant K, Welsh PA, White J, Topol EJ. A prospective, blinded determination of the natural history of aspirin resistance among stable patients with cardiovascular disease. J Am Coll Cardiol 2003; 41(6): 961-5.
    • (2003) J Am Coll Cardiol , vol.41 , Issue.6 , pp. 961-965
    • Gum, P.A.1    Kottke-Marchant, K.2    Welsh, P.A.3    White, J.4    Topol, E.J.5
  • 43
    • 10444265155 scopus 로고    scopus 로고
    • Aspirin and coronary artery disease
    • Maree AO, Fitzgerald DJ. Aspirin and coronary artery disease. Thromb Haemost 2004; 92(6): 1175-81.
    • (2004) Thromb Haemost , vol.92 , Issue.6 , pp. 1175-1181
    • Maree, A.O.1    Fitzgerald, D.J.2
  • 44
    • 33644886913 scopus 로고    scopus 로고
    • Aspirin and clopidogrel resistance: An emerging clinical entity
    • Wang TH, Bhatt DL, Topol EJ. Aspirin and clopidogrel resistance: an emerging clinical entity. Eur Heart J 2006; 27(6): 647-54.
    • (2006) Eur Heart J , vol.27 , Issue.6 , pp. 647-654
    • Wang, T.H.1    Bhatt, D.L.2    Topol, E.J.3
  • 46
    • 58249142825 scopus 로고    scopus 로고
    • Variability in responsiveness to oral antiplatelet therapy
    • Angiolillo DJ. Variability in responsiveness to oral antiplatelet therapy. Am J Cardiol 2009; 103(3 Suppl): 27A-34A.
    • (2009) Am J Cardiol , vol.103 , Issue.3 SUPPL.
    • Angiolillo, D.J.1
  • 47
    • 67649553482 scopus 로고    scopus 로고
    • Antiplatelet drug 'resistance'. Part 2: Laboratory resistance to antiplatelet drugs-fact or artifact?
    • Gorog DA, Sweeny JM, Fuster V. Antiplatelet drug 'resistance'. Part 2: laboratory resistance to antiplatelet drugs-fact or artifact? Nat Rev Cardiol 2009; 6(5): 365-73.
    • (2009) Nat Rev Cardiol , vol.6 , Issue.5 , pp. 365-373
    • Gorog, D.A.1    Sweeny, J.M.2    Fuster, V.3
  • 48
    • 67649654260 scopus 로고    scopus 로고
    • Antiplatelet drug 'resistance'. Part 1: Mechanisms and clinical measurements
    • Sweeny JM, Gorog DA, Fuster V. Antiplatelet drug 'resistance'. Part 1: mechanisms and clinical measurements. Nat Rev Cardiol 2009; 6(4): 273-82.
    • (2009) Nat Rev Cardiol , vol.6 , Issue.4 , pp. 273-282
    • Sweeny, J.M.1    Gorog, D.A.2    Fuster, V.3
  • 49
    • 24944474901 scopus 로고    scopus 로고
    • Aspirin resistance: Position paper of the Working Group on Aspirin Resistance
    • Michelson AD, Cattaneo M, Eikelboom JW, et al. Aspirin resistance: position paper of the Working Group on Aspirin Resistance. J Thromb Haemost 2005; 3(6): 1309-11.
    • (2005) J Thromb Haemost , vol.3 , Issue.6 , pp. 1309-1311
    • Michelson, A.D.1    Cattaneo, M.2    Eikelboom, J.W.3
  • 50
    • 0141762320 scopus 로고    scopus 로고
    • Pharmacokinetic and pharmacodynamic differences between two low dosages of aspirin may affect therapeutic outcomes
    • Cerletti C, Dell'Elba G, Manarini S, et al. Pharmacokinetic and pharmacodynamic differences between two low dosages of aspirin may affect therapeutic outcomes. Clin Pharmacokinet 2003; 42(12): 1059-70.
    • (2003) Clin Pharmacokinet , vol.42 , Issue.12 , pp. 1059-1070
    • Cerletti, C.1    Dell'Elba, G.2    Manarini, S.3
  • 52
    • 21444446653 scopus 로고    scopus 로고
    • Aspirin resistance: An evaluation of current evidence and measurement methods
    • Martin CP, Talbert RL. Aspirin resistance: an evaluation of current evidence and measurement methods. Pharmacotherapy 2005; 25(7): 942-53.
    • (2005) Pharmacotherapy , vol.25 , Issue.7 , pp. 942-953
    • Martin, C.P.1    Talbert, R.L.2
  • 53
    • 18744402157 scopus 로고    scopus 로고
    • Aspirin resistance after coronary artery bypass grafting
    • Zimmermann N, Kienzle P, Weber AA, et al. Aspirin resistance after coronary artery bypass grafting. J Thorac Cardiovasc Surg 2001; 121(5): 982-4.
    • (2001) J Thorac Cardiovasc Surg , vol.121 , Issue.5 , pp. 982-984
    • Zimmermann, N.1    Kienzle, P.2    Weber, A.A.3
  • 54
    • 23244440960 scopus 로고    scopus 로고
    • Resistance to aspirin in patients after coronary artery bypass grafting is transient: Impact on the monitoring of aspirin antiplatelet therapy
    • Golanski J, Chlopicki S, Golanski R, Gresner P, Iwaszkiewicz A, Watala C. Resistance to aspirin in patients after coronary artery bypass grafting is transient: impact on the monitoring of aspirin antiplatelet therapy. Ther Drug Monit 2005; 27(4): 484-90.
    • (2005) Ther Drug Monit , vol.27 , Issue.4 , pp. 484-490
    • Golanski, J.1    Chlopicki, S.2    Golanski, R.3    Gresner, P.4    Iwaszkiewicz, A.5    Watala, C.6
  • 55
    • 0025997575 scopus 로고
    • Effects of acetylsalicylic acid in stroke patients. Evidence of nonresponders in a subpopulation of treated patients
    • Grotemeyer KH. Effects of acetylsalicylic acid in stroke patients. Evidence of nonresponders in a subpopulation of treated patients. Thromb Res 1991; 63(6): 587-93.
    • (1991) Thromb Res , vol.63 , Issue.6 , pp. 587-593
    • Grotemeyer, K.H.1
  • 56
    • 0027279350 scopus 로고
    • Two-year follow-up of aspirin responder and aspirin non responder. A pilot-study including 180 post-stroke patients
    • Grotemeyer KH, Scharafinski HW, Husstedt IW. Two-year follow-up of aspirin responder and aspirin non responder. A pilot-study including 180 post-stroke patients. Thromb Res 1993; 71(5): 397-403.
    • (1993) Thromb Res , vol.71 , Issue.5 , pp. 397-403
    • Grotemeyer, K.H.1    Scharafinski, H.W.2    Husstedt, I.W.3
  • 57
    • 0027970934 scopus 로고
    • Development of aspirin resistance in persons with previous ischemic stroke
    • Helgason CM, Bolin KM, Hoff JA, et al. Development of aspirin resistance in persons with previous ischemic stroke. Stroke 1994; 25(12): 2331-6.
    • (1994) Stroke , vol.25 , Issue.12 , pp. 2331-2336
    • Helgason, C.M.1    Bolin, K.M.2    Hoff, J.A.3
  • 58
    • 0038370082 scopus 로고    scopus 로고
    • Aspirin dosage and thromboxane synthesis in patients with vascular disease
    • Hart RG, Leonard AD, Talbert RL, et al. Aspirin dosage and thromboxane synthesis in patients with vascular disease. Pharmacotherapy 2003; 23(5): 579-84.
    • (2003) Pharmacotherapy , vol.23 , Issue.5 , pp. 579-584
    • Hart, R.G.1    Leonard, A.D.2    Talbert, R.L.3
  • 59
    • 0037046196 scopus 로고    scopus 로고
    • Aspirin-resistant thromboxane biosynthesis and the risk of myocardial infarction, stroke, or cardiovascular death in patients at high risk for cardiovascular events
    • Eikelboom JW, Hirsh J, Weitz JI, Johnston M, Yi Q, Yusuf S. Aspirin-resistant thromboxane biosynthesis and the risk of myocardial infarction, stroke, or cardiovascular death in patients at high risk for cardiovascular events. Circulation 2002; 105(14): 1650-5.
    • (2002) Circulation , vol.105 , Issue.14 , pp. 1650-1655
    • Eikelboom, J.W.1    Hirsh, J.2    Weitz, J.I.3    Johnston, M.4    Yi, Q.5    Yusuf, S.6
  • 60
    • 33747088257 scopus 로고    scopus 로고
    • Residual arachidonic acid-induced platelet activation via an adenosine diphosphate-dependent but cyclooxygenase-1-and cyclooxygenase-2-independent pathway: A 700-patient study of aspirin resistance
    • Frelinger AL, 3rd, Furman MI, Linden MD, et al. Residual arachidonic acid-induced platelet activation via an adenosine diphosphate-dependent but cyclooxygenase-1-and cyclooxygenase-2-independent pathway: a 700-patient study of aspirin resistance. Circulation 2006; 113(25): 2888-96.
    • (2006) Circulation , vol.113 , Issue.25 , pp. 2888-2896
    • Frelinger III, A.L.1    Furman, M.I.2    Linden, M.D.3
  • 61
    • 34347340649 scopus 로고    scopus 로고
    • Evaluation of doserelated effects of aspirin on platelet function: Results from the Aspirin-Induced Platelet Effect (ASPECT) study
    • Gurbel PA, Bliden KP, DiChiara J, et al. Evaluation of doserelated effects of aspirin on platelet function: results from the Aspirin-Induced Platelet Effect (ASPECT) study. Circulation 2007; 115(25): 3156-64.
    • (2007) Circulation , vol.115 , Issue.25 , pp. 3156-3164
    • Gurbel, P.A.1    Bliden, K.P.2    DiChiara, J.3
  • 62
    • 12844269195 scopus 로고    scopus 로고
    • Biological assessment of aspirin efficacy on healthy individuals: Heterogeneous response or aspirin failure?
    • Gonzalez-Conejero R, Rivera J, Corral J, Acuna C, Guerrero JA, Vicente V. Biological assessment of aspirin efficacy on healthy individuals: heterogeneous response or aspirin failure? Stroke 2005; 36(2): 276-80.
    • (2005) Stroke , vol.36 , Issue.2 , pp. 276-280
    • Gonzalez-Conejero, R.1    Rivera, J.2    Corral, J.3    Acuna, C.4    Guerrero, J.A.5    Vicente, V.6
  • 63
    • 34547760330 scopus 로고    scopus 로고
    • A comparison of six major platelet function tests to determine the prevalence of aspirin resistance in patients with stable coronary artery disease
    • Lordkipanidze M, Pharand C, Schampaert E, Turgeon J, Palisaitis DA, Diodati JG. A comparison of six major platelet function tests to determine the prevalence of aspirin resistance in patients with stable coronary artery disease. Eur Heart J 2007; 28(14): 1702-8.
    • (2007) Eur Heart J , vol.28 , Issue.14 , pp. 1702-1708
    • Lordkipanidze, M.1    Pharand, C.2    Schampaert, E.3    Turgeon, J.4    Palisaitis, D.A.5    Diodati, J.G.6
  • 64
    • 77953160638 scopus 로고    scopus 로고
    • A comparison of platelet function tests and thromboxane metabolites to evaluate aspirin response in healthy individuals and patients with coronary artery disease
    • Grove EL, Hvas AM, Johnsen HL, et al. A comparison of platelet function tests and thromboxane metabolites to evaluate aspirin response in healthy individuals and patients with coronary artery disease. Thromb Haemost 2010; 103(6): 1245-53.
    • (2010) Thromb Haemost , vol.103 , Issue.6 , pp. 1245-1253
    • Grove, E.L.1    Hvas, A.M.2    Johnsen, H.L.3
  • 65
    • 77249113768 scopus 로고    scopus 로고
    • Comparison of platelet function tests in predicting clinical outcome in patients undergoing coronary stent implantation
    • Breet NJ, van Werkum JW, Bouman HJ, et al. Comparison of platelet function tests in predicting clinical outcome in patients undergoing coronary stent implantation. JAMA 2010; 303(8): 754-62.
    • (2010) JAMA , vol.303 , Issue.8 , pp. 754-762
    • Breet, N.J.1    van Werkum, J.W.2    Bouman, H.J.3
  • 66
    • 34248547883 scopus 로고    scopus 로고
    • Heritability of platelet responsiveness to aspirin in activation pathways directly and indirectly related to cyclooxygenase-1
    • Faraday N, Yanek LR, Mathias R, et al. Heritability of platelet responsiveness to aspirin in activation pathways directly and indirectly related to cyclooxygenase-1. Circulation 2007; 115(19): 2490-6.
    • (2007) Circulation , vol.115 , Issue.19 , pp. 2490-2496
    • Faraday, N.1    Yanek, L.R.2    Mathias, R.3
  • 67
    • 80052167250 scopus 로고    scopus 로고
    • Impact of platelet reactivity on clinical outcomes after percutaneous coronary intervention. A collaborative meta-analysis of individual participant data
    • Brar SS, ten Berg J, Marcucci R, et al. Impact of platelet reactivity on clinical outcomes after percutaneous coronary intervention. A collaborative meta-analysis of individual participant data. J Am Coll Cardiol 2011; 58(19): 1945-54.
    • (2011) J Am Coll Cardiol , vol.58 , Issue.19 , pp. 1945-1954
    • Brar, S.S.1    ten Berg, J.2    Marcucci, R.3
  • 68
    • 59849120163 scopus 로고    scopus 로고
    • Cardiovascular death and nonfatal myocardial infarction in acute coronary syndrome patients receiving coronary stenting are predicted by residual platelet reactivity to ADP detected by a point-ofcare assay: A 12-month follow-up
    • Marcucci R, Gori AM, Paniccia R, et al. Cardiovascular death and nonfatal myocardial infarction in acute coronary syndrome patients receiving coronary stenting are predicted by residual platelet reactivity to ADP detected by a point-ofcare assay: a 12-month follow-up. Circulation 2009; 119(2): 237-42.
    • (2009) Circulation , vol.119 , Issue.2 , pp. 237-242
    • Marcucci, R.1    Gori, A.M.2    Paniccia, R.3
  • 69
    • 33845297690 scopus 로고    scopus 로고
    • Value of platelet reactivity in predicting response to treatment and clinical outcome in patients undergoing primary coronary intervention: Insights into the STRATEGY Study
    • Campo G, Valgimigli M, Gemmati D, et al. Value of platelet reactivity in predicting response to treatment and clinical outcome in patients undergoing primary coronary intervention: insights into the STRATEGY Study. J Am Coll Cardiol 2006; 48(11): 2178-85.
    • (2006) J Am Coll Cardiol , vol.48 , Issue.11 , pp. 2178-2185
    • Campo, G.1    Valgimigli, M.2    Gemmati, D.3
  • 70
    • 84863338161 scopus 로고    scopus 로고
    • Different prognostic significance of high on-treatment platelet reactivity as assessed by the VerifyNow P2Y12 assay after coronary stenting in patients with and without acute myocardial infarction
    • Ahn SG, Lee SH, Yoon JH, et al. Different prognostic significance of high on-treatment platelet reactivity as assessed by the VerifyNow P2Y12 assay after coronary stenting in patients with and without acute myocardial infarction. JACC Cardiovasc Interv 2012; 5(3): 259-67.
    • (2012) JACC Cardiovasc Interv , vol.5 , Issue.3 , pp. 259-267
    • Ahn, S.G.1    Lee, S.H.2    Yoon, J.H.3
  • 71
    • 28444484957 scopus 로고    scopus 로고
    • Cyclooxygenase-1 haplotype modulates platelet response to aspirin
    • Maree AO, Curtin RJ, Chubb A, et al. Cyclooxygenase-1 haplotype modulates platelet response to aspirin. J Thromb Haemost 2005; 3(10): 2340-5.
    • (2005) J Thromb Haemost , vol.3 , Issue.10 , pp. 2340-2345
    • Maree, A.O.1    Curtin, R.J.2    Chubb, A.3
  • 72
    • 33645546989 scopus 로고    scopus 로고
    • Polymorphisms of COX-1 and GPVI associate with the antiplatelet effect of aspirin in coronary artery disease patients
    • Lepantalo A, Mikkelsson J, Resendiz JC, et al. Polymorphisms of COX-1 and GPVI associate with the antiplatelet effect of aspirin in coronary artery disease patients. Thromb Haemost 2006; 95(2): 253-9.
    • (2006) Thromb Haemost , vol.95 , Issue.2 , pp. 253-259
    • Lepantalo, A.1    Mikkelsson, J.2    Resendiz, J.C.3
  • 73
    • 0037256309 scopus 로고    scopus 로고
    • Genetic variation in cyclooxygenase 1: Effects on response to aspirin
    • Halushka MK, Walker LP, Halushka PV. Genetic variation in cyclooxygenase 1: effects on response to aspirin. Clin Pharmacol Ther 2003; 73(1): 122-30.
    • (2003) Clin Pharmacol Ther , vol.73 , Issue.1 , pp. 122-130
    • Halushka, M.K.1    Walker, L.P.2    Halushka, P.V.3
  • 74
    • 77957703701 scopus 로고    scopus 로고
    • Platelet gene polymorphisms and risk of bleeding in patients undergoing elective coronary angiography: A genetic substudy of the PRAGUE-8 trial
    • Motovska Z, Kvasnicka J, Hajkova J, et al. Platelet gene polymorphisms and risk of bleeding in patients undergoing elective coronary angiography: a genetic substudy of the PRAGUE-8 trial. Atherosclerosis 2010; 212(2): 548-52.
    • (2010) Atherosclerosis , vol.212 , Issue.2 , pp. 548-552
    • Motovska, Z.1    Kvasnicka, J.2    Hajkova, J.3
  • 75
    • 38649098154 scopus 로고    scopus 로고
    • Platelet responsiveness to in vitro aspirin is independent of COX-1 and COX-2 protein levels and polymorphisms
    • Takahashi S, Ushida M, Komine R, et al. Platelet responsiveness to in vitro aspirin is independent of COX-1 and COX-2 protein levels and polymorphisms. Thromb Res 2008; 121(4): 509-17.
    • (2008) Thromb Res , vol.121 , Issue.4 , pp. 509-517
    • Takahashi, S.1    Ushida, M.2    Komine, R.3
  • 76
    • 64849112905 scopus 로고    scopus 로고
    • Cyclooxygenase-1 haplotype C50T/A-842G does not affect platelet response to aspirin
    • Pettinella C, Romano M, Stuppia L, Santilli F, Liani R, Davi G. Cyclooxygenase-1 haplotype C50T/A-842G does not affect platelet response to aspirin. Thromb Haemost 2009; 101(4): 687-90.
    • (2009) Thromb Haemost , vol.101 , Issue.4 , pp. 687-690
    • Pettinella, C.1    Romano, M.2    Stuppia, L.3    Santilli, F.4    Liani, R.5    Davi, G.6
  • 77
    • 60849137489 scopus 로고    scopus 로고
    • Lack of association between aspirin responsiveness and seven candidate gene haplotypes in patients with symptomatic vascular disease
    • Kunicki TJ, Williams SA, Nugent DJ, et al. Lack of association between aspirin responsiveness and seven candidate gene haplotypes in patients with symptomatic vascular disease. Thromb Haemost 2009; 101(1): 123-33.
    • (2009) Thromb Haemost , vol.101 , Issue.1 , pp. 123-133
    • Kunicki, T.J.1    Williams, S.A.2    Nugent, D.J.3
  • 78
    • 34249996115 scopus 로고    scopus 로고
    • A common allele on chromosome 9 associated with coronary heart disease
    • McPherson R, Pertsemlidis A, Kavaslar N, et al. A common allele on chromosome 9 associated with coronary heart disease. Science 2007; 316(5830): 1488-91.
    • (2007) Science , vol.316 , Issue.5830 , pp. 1488-1491
    • McPherson, R.1    Pertsemlidis, A.2    Kavaslar, N.3
  • 79
    • 46749115957 scopus 로고    scopus 로고
    • The C50T polymorphism of the cyclooxygenase-1 gene and the risk of thrombotic events during low-dose therapy with acetyl salicylic acid
    • Clappers N, van Oijen MG, Sundaresan S, et al. The C50T polymorphism of the cyclooxygenase-1 gene and the risk of thrombotic events during low-dose therapy with acetyl salicylic acid. Thromb Haemost 2008; 100(1): 70-5.
    • (2008) Thromb Haemost , vol.100 , Issue.1 , pp. 70-75
    • Clappers, N.1    van Oijen, M.G.2    Sundaresan, S.3
  • 80
    • 34250625249 scopus 로고    scopus 로고
    • Frequency of genetic polymorphisms of COX1, GPIIIa and P2Y1 in a Chinese population and association with attenuated response to aspirin
    • Li Q, Chen BL, Ozdemir V, et al. Frequency of genetic polymorphisms of COX1, GPIIIa and P2Y1 in a Chinese population and association with attenuated response to aspirin. Pharmacogenomics 2007; 8(6): 577-86.
    • (2007) Pharmacogenomics , vol.8 , Issue.6 , pp. 577-586
    • Li, Q.1    Chen, B.L.2    Ozdemir, V.3
  • 81
    • 79960175185 scopus 로고    scopus 로고
    • Polymorphisms associated with in vitro aspirin resistance are not associated with clinical outcomes in patients with coronary artery disease who report regular aspirin use
    • Voora D, Horton J, Shah SH, Shaw LK, Newby LK. Polymorphisms associated with in vitro aspirin resistance are not associated with clinical outcomes in patients with coronary artery disease who report regular aspirin use. Am Heart J 2011; 162(1): 166-72 e1.
    • (2011) Am Heart J , vol.162 , Issue.1
    • Voora, D.1    Horton, J.2    Shah, S.H.3    Shaw, L.K.4    Newby, L.K.5
  • 82
    • 84874788096 scopus 로고    scopus 로고
    • Frequency, risk factors, prognosis, and genetic polymorphism of the cyclooxygenase-1 gene for aspirin resistance in elderly Chinese patients with cardiovascular disease
    • Fan L, Cao J, Liu L, et al. Frequency, risk factors, prognosis, and genetic polymorphism of the cyclooxygenase-1 gene for aspirin resistance in elderly Chinese patients with cardiovascular disease. Gerontology 2013; 59(2): 122-31.
    • (2013) Gerontology , vol.59 , Issue.2 , pp. 122-131
    • Fan, L.1    Cao, J.2    Liu, L.3
  • 83
    • 44349123127 scopus 로고    scopus 로고
    • Cyclooxygenase-2 polymorphisms and risk of rheumatoid arthritis in Koreans
    • Yun HR, Lee SO, Choi EJ, Shin HD, Jun JB, Bae SC. Cyclooxygenase-2 polymorphisms and risk of rheumatoid arthritis in Koreans. J Rheumatol 2008; 35(5): 763-9.
    • (2008) J Rheumatol , vol.35 , Issue.5 , pp. 763-769
    • Yun, H.R.1    Lee, S.O.2    Choi, E.J.3    Shin, H.D.4    Jun, J.B.5    Bae, S.C.6
  • 84
    • 0035205852 scopus 로고    scopus 로고
    • Increased susceptibility to ischemic brain injury in cyclooxygenase-1-deficient mice
    • Iadecola C, Sugimoto K, Niwa K, Kazama K, Ross ME. Increased susceptibility to ischemic brain injury in cyclooxygenase-1-deficient mice. J Cereb Blood Flow Metab 2001; 21(12): 1436-41.
    • (2001) J Cereb Blood Flow Metab , vol.21 , Issue.12 , pp. 1436-1441
    • Iadecola, C.1    Sugimoto, K.2    Niwa, K.3    Kazama, K.4    Ross, M.E.5
  • 85
    • 0035970509 scopus 로고    scopus 로고
    • Cyclooxygenase-1 participates in selected vasodilator responses of the cerebral circulation
    • Niwa K, Haensel C, Ross ME, Iadecola C. Cyclooxygenase-1 participates in selected vasodilator responses of the cerebral circulation. Circ Res 2001; 88(6): 600-8.
    • (2001) Circ Res , vol.88 , Issue.6 , pp. 600-608
    • Niwa, K.1    Haensel, C.2    Ross, M.E.3    Iadecola, C.4
  • 86
    • 84862762127 scopus 로고    scopus 로고
    • Decreased cyclooxygenase inhibition by aspirin in polymorphic variants of human prostaglandin H synthase-1
    • Liu W, Poole EM, Ulrich CM, Kulmacz RJ. Decreased cyclooxygenase inhibition by aspirin in polymorphic variants of human prostaglandin H synthase-1. Pharmacogenet Genomics 2012; 22(7): 525-37.
    • (2012) Pharmacogenet Genomics , vol.22 , Issue.7 , pp. 525-537
    • Liu, W.1    Poole, E.M.2    Ulrich, C.M.3    Kulmacz, R.J.4
  • 87
    • 84874460990 scopus 로고    scopus 로고
    • Correlation analysis of aspirin resistance and cycloxygenase-1 haplotype in old Chinese patients with cardio-cerebrovascular diseases
    • Li XL, Cao J, Fan L, et al. [Correlation analysis of aspirin resistance and cycloxygenase-1 haplotype in old Chinese patients with cardio-cerebrovascular diseases]. Zhongguo Ying Yong Sheng Li Xue Za Zhi 2012; 28(3): 225-9.
    • (2012) Zhongguo Ying Yong Sheng Li Xue Za Zhi , vol.28 , Issue.3 , pp. 225-229
    • Li, X.L.1    Cao, J.2    Fan, L.3
  • 88
    • 0036790471 scopus 로고    scopus 로고
    • Common promoter variant in cyclooxygenase-2 represses gene expression: Evidence of role in acute-phase inflammatory response
    • Papafili A, Hill MR, Brull DJ, et al. Common promoter variant in cyclooxygenase-2 represses gene expression: evidence of role in acute-phase inflammatory response. Arterioscler Thromb Vasc Biol 2002; 22(10): 1631-6.
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , Issue.10 , pp. 1631-1636
    • Papafili, A.1    Hill, M.R.2    Brull, D.J.3
  • 89
    • 16844364790 scopus 로고    scopus 로고
    • PTGS2 (COX-2)-765G > C promoter variant reduces risk of colorectal adenoma among nonusers of nonsteroidal anti-inflammatory drugs
    • Ulrich CM, Whitton J, Yu JH, et al. PTGS2 (COX-2)-765G > C promoter variant reduces risk of colorectal adenoma among nonusers of nonsteroidal anti-inflammatory drugs. Cancer Epidemiol Biomarkers Prev 2005; 14(3): 616-9.
    • (2005) Cancer Epidemiol Biomarkers Prev , vol.14 , Issue.3 , pp. 616-619
    • Ulrich, C.M.1    Whitton, J.2    Yu, J.H.3
  • 90
    • 67349271287 scopus 로고    scopus 로고
    • Variation in eicosanoid genes, non-fatal myocardial infarction and ischemic stroke
    • Lemaitre RN, Rice K, Marciante K, et al. Variation in eicosanoid genes, non-fatal myocardial infarction and ischemic stroke. Atherosclerosis 2009; 204(2): e58-63.
    • (2009) Atherosclerosis , vol.204 , Issue.2
    • Lemaitre, R.N.1    Rice, K.2    Marciante, K.3
  • 91
    • 36949037990 scopus 로고    scopus 로고
    • Alternative splicing of platelet cyclooxygenase-2 mRNA in patients after coronary artery bypass grafting
    • Censarek P, Steger G, Paolini C, et al. Alternative splicing of platelet cyclooxygenase-2 mRNA in patients after coronary artery bypass grafting. Thromb Haemost 2007; 98(6): 1309-15.
    • (2007) Thromb Haemost , vol.98 , Issue.6 , pp. 1309-1315
    • Censarek, P.1    Steger, G.2    Paolini, C.3
  • 92
    • 31044441042 scopus 로고    scopus 로고
    • Biological basis for the cardiovascular consequences of COX-2 inhibition: Therapeutic challenges and opportunities
    • Grosser T, Fries S, FitzGerald GA. Biological basis for the cardiovascular consequences of COX-2 inhibition: therapeutic challenges and opportunities. J Clin Invest 2006; 116(1): 4-15.
    • (2006) J Clin Invest , vol.116 , Issue.1 , pp. 4-15
    • Grosser, T.1    Fries, S.2    FitzGerald, G.A.3
  • 93
    • 23244445988 scopus 로고    scopus 로고
    • Cyclooxygenase inhibition and cardiovascular risk
    • Antman EM, DeMets D, Loscalzo J. Cyclooxygenase inhibition and cardiovascular risk. Circulation 2005; 112(5): 759-70.
    • (2005) Circulation , vol.112 , Issue.5 , pp. 759-770
    • Antman, E.M.1    DeMets, D.2    Loscalzo, J.3
  • 94
    • 2342504605 scopus 로고    scopus 로고
    • A polymorphism in the cyclooxygenase 2 gene as an inherited protective factor against myocardial infarction and stroke
    • Cipollone F, Toniato E, Martinotti S, et al. A polymorphism in the cyclooxygenase 2 gene as an inherited protective factor against myocardial infarction and stroke. JAMA 2004; 291(18): 2221-8.
    • (2004) JAMA , vol.291 , Issue.18 , pp. 2221-2228
    • Cipollone, F.1    Toniato, E.2    Martinotti, S.3
  • 95
    • 33646827887 scopus 로고    scopus 로고
    • Protective effect of the G-765C COX-2 polymorphism on subclinical atherosclerosis and inflammatory markers in asymptomatic subjects with cardiovascular risk factors
    • Orbe J, Beloqui O, Rodriguez JA, Belzunce MS, Roncal C, Paramo JA. Protective effect of the G-765C COX-2 polymorphism on subclinical atherosclerosis and inflammatory markers in asymptomatic subjects with cardiovascular risk factors. Clin Chim Acta 2006; 368(1-2): 138-43.
    • (2006) Clin Chim Acta , vol.368 , Issue.1-2 , pp. 138-143
    • Orbe, J.1    Beloqui, O.2    Rodriguez, J.A.3    Belzunce, M.S.4    Roncal, C.5    Paramo, J.A.6
  • 96
    • 33646086470 scopus 로고    scopus 로고
    • The COX-2 G/C-765 polymorphism may modulate the occurrence of cerebrovascular ischemia
    • Colaizzo D, Fofi L, Tiscia G, et al. The COX-2 G/C-765 polymorphism may modulate the occurrence of cerebrovascular ischemia. Blood Coagul Fibrinolysis 2006; 17(2): 93-6.
    • (2006) Blood Coagul Fibrinolysis , vol.17 , Issue.2 , pp. 93-96
    • Colaizzo, D.1    Fofi, L.2    Tiscia, G.3
  • 97
    • 80055116248 scopus 로고    scopus 로고
    • Genetic determinants of platelet reactivity during acetylsalicylic acid therapy in diabetic patients: Evaluation of 27 polymorphisms within candidate genes
    • Postula M, Kaplon-Cieslicka A, Rosiak M, et al. Genetic determinants of platelet reactivity during acetylsalicylic acid therapy in diabetic patients: evaluation of 27 polymorphisms within candidate genes. J Thromb Haemost 2011; 9(11): 2291-301.
    • (2011) J Thromb Haemost , vol.9 , Issue.11 , pp. 2291-2301
    • Postula, M.1    Kaplon-Cieslicka, A.2    Rosiak, M.3
  • 98
    • 47249143688 scopus 로고    scopus 로고
    • Pharmacogenetics of aspirin resistance: A comprehensive systematic review
    • Goodman T, Ferro A, Sharma P. Pharmacogenetics of aspirin resistance: a comprehensive systematic review. Br J Clin Pharmacol 2008; 66(2): 222-32.
    • (2008) Br J Clin Pharmacol , vol.66 , Issue.2 , pp. 222-232
    • Goodman, T.1    Ferro, A.2    Sharma, P.3
  • 99
    • 0031841377 scopus 로고    scopus 로고
    • Cytochrome P4502C9: An enzyme of major importance in human drug metabolism
    • Miners JO, Birkett DJ. Cytochrome P4502C9: an enzyme of major importance in human drug metabolism. Br J Clin Pharmacol 1998; 45(6): 525-38.
    • (1998) Br J Clin Pharmacol , vol.45 , Issue.6 , pp. 525-538
    • Miners, J.O.1    Birkett, D.J.2
  • 100
    • 0030699360 scopus 로고    scopus 로고
    • Genetic polymorphism in the human UGT1A6 (planar phenol) UDPglucuronosyltransferase: Pharmacological implications
    • Ciotti M, Marrone A, Potter C, Owens IS. Genetic polymorphism in the human UGT1A6 (planar phenol) UDPglucuronosyltransferase: pharmacological implications. Pharmacogenetics 1997; 7(6): 485-95.
    • (1997) Pharmacogenetics , vol.7 , Issue.6 , pp. 485-495
    • Ciotti, M.1    Marrone, A.2    Potter, C.3    Owens, I.S.4
  • 101
    • 83655202895 scopus 로고    scopus 로고
    • Polymorphisms of Aspirin-Metabolizing Enzymes CYP2C9, NAT2 and UGT1A6 in Aspirin-Intolerant Urticaria
    • Palikhe NS, Kim SH, Nam YH, Ye YM, Park HS. Polymorphisms of Aspirin-Metabolizing Enzymes CYP2C9, NAT2 and UGT1A6 in Aspirin-Intolerant Urticaria. Allergy Asthma Immunol Res 2011; 3(4): 273-6.
    • (2011) Allergy Asthma Immunol Res , vol.3 , Issue.4 , pp. 273-276
    • Palikhe, N.S.1    Kim, S.H.2    Nam, Y.H.3    Ye, Y.M.4    Park, H.S.5
  • 102
    • 0035328829 scopus 로고    scopus 로고
    • CYP2C9 and UGT1A6 genotypes modulate the protective effect of aspirin on colon adenoma risk
    • Bigler J, Whitton J, Lampe JW, Fosdick L, Bostick RM, Potter JD. CYP2C9 and UGT1A6 genotypes modulate the protective effect of aspirin on colon adenoma risk. Cancer Res 2001; 61(9): 3566-9.
    • (2001) Cancer Res , vol.61 , Issue.9 , pp. 3566-3569
    • Bigler, J.1    Whitton, J.2    Lampe, J.W.3    Fosdick, L.4    Bostick, R.M.5    Potter, J.D.6
  • 103
    • 34547655744 scopus 로고    scopus 로고
    • ACC/AHA 2007 guidelines for the management of patients with unstable angina/non-ST-Elevation myocardial infarction
    • A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines for the Management of Patients With Unstable Angina/Non-STElevation Myocardial Infarction) developed in collaboration with the American College of Emergency Physicians, the Society for Cardiovascular Angiography and Interventions, and the Society of Thoracic Surgeons endorsed by the American Association of Cardiovascular and Pulmonary Rehabilitation and the Society for Academic Emergency Medicine
    • Anderson JL, Adams CD, Antman EM, et al. ACC/AHA 2007 guidelines for the management of patients with unstable angina/non-ST-Elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines for the Management of Patients With Unstable Angina/Non-STElevation Myocardial Infarction) developed in collaboration with the American College of Emergency Physicians, the Society for Cardiovascular Angiography and Interventions, and the Society of Thoracic Surgeons endorsed by the American Association of Cardiovascular and Pulmonary Rehabilitation and the Society for Academic Emergency Medicine. J Am Coll Cardiol 2007; 50(7): e1-e157.
    • (2007) J Am Coll Cardiol , vol.50 , Issue.7
    • Anderson, J.L.1    Adams, C.D.2    Antman, E.M.3
  • 104
    • 70450199115 scopus 로고    scopus 로고
    • Focused updates
    • ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction (updating the 2004 guideline and 2007 focused update) and ACC/AHA/SCAI guidelines on percutaneous coronary intervention (updating the 2005 guideline and 2007 focused update) a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines
    • Kushner FG, Hand M, Smith SC, Jr, et al. 2009 focused updates: ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction (updating the 2004 guideline and 2007 focused update) and ACC/AHA/SCAI guidelines on percutaneous coronary intervention (updating the 2005 guideline and 2007 focused update) a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 2009; 54(23): 2205-41.
    • (2009) J Am Coll Cardiol , vol.54 , Issue.23 , pp. 2205-2241
    • Kushner, F.G.1    Hand, M.2    Smith Jr., S.C.3
  • 105
    • 27644548513 scopus 로고    scopus 로고
    • Addition of clopidogrel to aspirin in 45,852 patients with acute myocardial infarction: Randomised placebo-controlled trial
    • Chen ZM, Jiang LX, Chen YP, et al. Addition of clopidogrel to aspirin in 45,852 patients with acute myocardial infarction: randomised placebo-controlled trial. Lancet 2005; 366(9497): 1607-21.
    • (2005) Lancet , vol.366 , Issue.9497 , pp. 1607-1621
    • Chen, Z.M.1    Jiang, L.X.2    Chen, Y.P.3
  • 106
    • 20144373281 scopus 로고    scopus 로고
    • Addition of clopidogrel to aspirin and fibrinolytic therapy for myocardial infarction with ST-segment elevation
    • Sabatine MS, Cannon CP, Gibson CM, et al. Addition of clopidogrel to aspirin and fibrinolytic therapy for myocardial infarction with ST-segment elevation. N Engl J Med 2005; 352(12): 1179-89.
    • (2005) N Engl J Med , vol.352 , Issue.12 , pp. 1179-1189
    • Sabatine, M.S.1    Cannon, C.P.2    Gibson, C.M.3
  • 107
    • 0035899289 scopus 로고    scopus 로고
    • Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation
    • Yusuf S, Zhao F, Mehta SR, Chrolavicius S, Tognoni G, Fox KK. Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation. N Engl J Med 2001; 345(7): 494-502.
    • (2001) N Engl J Med , vol.345 , Issue.7 , pp. 494-502
    • Yusuf, S.1    Zhao, F.2    Mehta, S.R.3    Chrolavicius, S.4    Tognoni, G.5    Fox, K.K.6
  • 109
    • 0034978187 scopus 로고    scopus 로고
    • Molecular identification and characterization of the platelet ADP receptor targeted by thienopyridine antithrombotic drugs
    • Foster CJ, Prosser DM, Agans JM, et al. Molecular identification and characterization of the platelet ADP receptor targeted by thienopyridine antithrombotic drugs. J Clin Invest 2001; 107(12): 1591-8.
    • (2001) J Clin Invest , vol.107 , Issue.12 , pp. 1591-1598
    • Foster, C.J.1    Prosser, D.M.2    Agans, J.M.3
  • 110
    • 8344221349 scopus 로고    scopus 로고
    • Clopidogrel resistance is associated with increased risk of recurrent atherothrombotic events in patients with acute myocardial infarction
    • Matetzky S, Shenkman B, Guetta V, et al. Clopidogrel resistance is associated with increased risk of recurrent atherothrombotic events in patients with acute myocardial infarction. Circulation 2004; 109(25): 3171-5.
    • (2004) Circulation , vol.109 , Issue.25 , pp. 3171-3175
    • Matetzky, S.1    Shenkman, B.2    Guetta, V.3
  • 111
    • 56549090507 scopus 로고    scopus 로고
    • Platelet reactivity to adenosine diphosphate and long-term ischemic event occurrence following percutaneous coronary intervention: A potential antiplatelet therapeutic target
    • Gurbel PA, Antonino MJ, Bliden KP, et al. Platelet reactivity to adenosine diphosphate and long-term ischemic event occurrence following percutaneous coronary intervention: a potential antiplatelet therapeutic target. Platelets 2008; 19(8): 595-604.
    • (2008) Platelets , vol.19 , Issue.8 , pp. 595-604
    • Gurbel, P.A.1    Antonino, M.J.2    Bliden, K.P.3
  • 112
    • 27644465874 scopus 로고    scopus 로고
    • Clopidogrel effect on platelet reactivity in patients with stent thrombosis: Results of the CREST Study
    • Gurbel PA, Bliden KP, Samara W, et al. Clopidogrel effect on platelet reactivity in patients with stent thrombosis: results of the CREST Study. J Am Coll Cardiol 2005; 46(10): 1827-32.
    • (2005) J Am Coll Cardiol , vol.46 , Issue.10 , pp. 1827-1832
    • Gurbel, P.A.1    Bliden, K.P.2    Samara, W.3
  • 113
    • 33750479499 scopus 로고    scopus 로고
    • Impact of the degree of peri-interventional platelet inhibition after loading with clopidogrel on early clinical outcome of elective coronary stent placement
    • Hochholzer W, Trenk D, Bestehorn HP, et al. Impact of the degree of peri-interventional platelet inhibition after loading with clopidogrel on early clinical outcome of elective coronary stent placement. J Am Coll Cardiol 2006; 48(9): 1742-50.
    • (2006) J Am Coll Cardiol , vol.48 , Issue.9 , pp. 1742-1750
    • Hochholzer, W.1    Trenk, D.2    Bestehorn, H.P.3
  • 114
    • 34447576539 scopus 로고    scopus 로고
    • Clopidogrel nonresponsiveness in patients undergoing percutaneous coronary intervention with stenting: A systematic review and meta-analysis
    • Snoep JD, Hovens MM, Eikenboom JC, van der Bom JG, Jukema JW, Huisman MV. Clopidogrel nonresponsiveness in patients undergoing percutaneous coronary intervention with stenting: a systematic review and meta-analysis. Am Heart J 2007; 154(2): 221-31.
    • (2007) Am Heart J , vol.154 , Issue.2 , pp. 221-231
    • Snoep, J.D.1    Hovens, M.M.2    Eikenboom, J.C.3    van der Bom, J.G.4    Jukema, J.W.5    Huisman, M.V.6
  • 116
    • 69249219296 scopus 로고    scopus 로고
    • Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy
    • Shuldiner AR, O'Connell JR, Bliden KP, et al. Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy. JAMA 2009; 302(8): 849-57.
    • (2009) JAMA , vol.302 , Issue.8 , pp. 849-857
    • Shuldiner, A.R.1    O'Connell, J.R.2    Bliden, K.P.3
  • 117
    • 84855953171 scopus 로고    scopus 로고
    • PharmGKB summary: Very important pharmacogene information for cytochrome P450, family 2, subfamily C, polypeptide 19
    • Scott SA, Sangkuhl K, Shuldiner AR, et al. PharmGKB summary: very important pharmacogene information for cytochrome P450, family 2, subfamily C, polypeptide 19. Pharmacogenet Genomics 2012; 22(2): 159-65.
    • (2012) Pharmacogenet Genomics , vol.22 , Issue.2 , pp. 159-165
    • Scott, S.A.1    Sangkuhl, K.2    Shuldiner, A.R.3
  • 118
    • 76349098199 scopus 로고    scopus 로고
    • Cytochrome 2C19*17 allelic variant, platelet aggregation, bleeding events, and stent thrombosis in clopidogrel-treated patients with coronary stent placement
    • Sibbing D, Koch W, Gebhard D, et al. Cytochrome 2C19*17 allelic variant, platelet aggregation, bleeding events, and stent thrombosis in clopidogrel-treated patients with coronary stent placement. Circulation 2010; 121(4): 512-8.
    • (2010) Circulation , vol.121 , Issue.4 , pp. 512-518
    • Sibbing, D.1    Koch, W.2    Gebhard, D.3
  • 119
    • 84155167902 scopus 로고    scopus 로고
    • Meta-analyses of the association between cytochrome CYP2C19 loss-and gainof-function polymorphisms and cardiovascular outcomes in patients with coronary artery disease treated with clopidogrel
    • Zabalza M, Subirana I, Sala J, et al. Meta-analyses of the association between cytochrome CYP2C19 loss-and gainof-function polymorphisms and cardiovascular outcomes in patients with coronary artery disease treated with clopidogrel. Heart 2012; 98(2): 100-8.
    • (2012) Heart , vol.98 , Issue.2 , pp. 100-108
    • Zabalza, M.1    Subirana, I.2    Sala, J.3
  • 120
    • 36348943475 scopus 로고    scopus 로고
    • Common polymorphisms of CYP2C19 and CYP2C9 affect the pharmacokinetic and pharmacodynamic response to clopidogrel but not prasugrel
    • Brandt JT, Close SL, Iturria SJ, et al. Common polymorphisms of CYP2C19 and CYP2C9 affect the pharmacokinetic and pharmacodynamic response to clopidogrel but not prasugrel. J Thromb Haemost 2007; 5(12): 2429-36.
    • (2007) J Thromb Haemost , vol.5 , Issue.12 , pp. 2429-2436
    • Brandt, J.T.1    Close, S.L.2    Iturria, S.J.3
  • 121
    • 58749094444 scopus 로고    scopus 로고
    • Cytochrome p-450 polymorphisms and response to clopidogrel
    • Mega JL, Close SL, Wiviott SD, et al. Cytochrome p-450 polymorphisms and response to clopidogrel. N Engl J Med 2009; 360(4): 354-62.
    • (2009) N Engl J Med , vol.360 , Issue.4 , pp. 354-362
    • Mega, J.L.1    Close, S.L.2    Wiviott, S.D.3
  • 122
    • 33749339075 scopus 로고    scopus 로고
    • Cytochrome P450 2C19 loss-of-function polymorphism is a major determinant of clopidogrel responsiveness in healthy subjects
    • Hulot JS, Bura A, Villard E, et al. Cytochrome P450 2C19 loss-of-function polymorphism is a major determinant of clopidogrel responsiveness in healthy subjects. Blood 2006; 108(7): 2244-7.
    • (2006) Blood , vol.108 , Issue.7 , pp. 2244-2247
    • Hulot, J.S.1    Bura, A.2    Villard, E.3
  • 123
    • 34548858712 scopus 로고    scopus 로고
    • Influence of CYP2C19 and CYP3A4 gene polymorphisms on clopidogrel responsiveness in healthy subjects
    • Fontana P, Hulot JS, De Moerloose P, Gaussem P. Influence of CYP2C19 and CYP3A4 gene polymorphisms on clopidogrel responsiveness in healthy subjects. J Thromb Haemost 2007; 5(10): 2153-5.
    • (2007) J Thromb Haemost , vol.5 , Issue.10 , pp. 2153-2155
    • Fontana, P.1    Hulot, J.S.2    De Moerloose, P.3    Gaussem, P.4
  • 124
    • 45249088224 scopus 로고    scopus 로고
    • The effect of CYP2C19 polymorphism on the pharmacokinetics and pharmacodynamics of clopidogrel: A possible mechanism for clopidogrel resistance
    • Kim KA, Park PW, Hong SJ, Park JY. The effect of CYP2C19 polymorphism on the pharmacokinetics and pharmacodynamics of clopidogrel: a possible mechanism for clopidogrel resistance. Clin Pharmacol Ther 2008; 84(2): 236-42.
    • (2008) Clin Pharmacol Ther , vol.84 , Issue.2 , pp. 236-242
    • Kim, K.A.1    Park, P.W.2    Hong, S.J.3    Park, J.Y.4
  • 125
    • 47649111604 scopus 로고    scopus 로고
    • The common gene variants of CYP2C19 affect pharmacokinetics and pharmacodynamics in an active metabolite of clopidogrel in healthy subjects
    • Umemura K, Furuta T, Kondo K. The common gene variants of CYP2C19 affect pharmacokinetics and pharmacodynamics in an active metabolite of clopidogrel in healthy subjects. J Thromb Haemost 2008; 6(8): 1439-41.
    • (2008) J Thromb Haemost , vol.6 , Issue.8 , pp. 1439-1441
    • Umemura, K.1    Furuta, T.2    Kondo, K.3
  • 126
    • 70249139788 scopus 로고    scopus 로고
    • Pharmacodynamic effect and clinical efficacy of clopidogrel and prasugrel with or without a proton-pump inhibitor: An analysis of two randomised trials
    • O'Donoghue ML, Braunwald E, Antman EM, et al. Pharmacodynamic effect and clinical efficacy of clopidogrel and prasugrel with or without a proton-pump inhibitor: an analysis of two randomised trials. Lancet 2009; 374(9694): 989-97.
    • (2009) Lancet , vol.374 , Issue.9694 , pp. 989-997
    • O'Donoghue, M.L.1    Braunwald, E.2    Antman, E.M.3
  • 127
    • 58749090547 scopus 로고    scopus 로고
    • Genetic determinants of response to clopidogrel and cardiovascular events
    • Simon T, Verstuyft C, Mary-Krause M, et al. Genetic determinants of response to clopidogrel and cardiovascular events. N Engl J Med 2009; 360(4): 363-75.
    • (2009) N Engl J Med , vol.360 , Issue.4 , pp. 363-375
    • Simon, T.1    Verstuyft, C.2    Mary-Krause, M.3
  • 128
    • 58249135635 scopus 로고    scopus 로고
    • Cytochrome P450 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction: A cohort study
    • Collet JP, Hulot JS, Pena A, et al. Cytochrome P450 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction: a cohort study. Lancet 2009; 373(9660): 309-17.
    • (2009) Lancet , vol.373 , Issue.9660 , pp. 309-317
    • Collet, J.P.1    Hulot, J.S.2    Pena, A.3
  • 129
    • 43049179414 scopus 로고    scopus 로고
    • Cytochrome P450 2C19 681G>A polymorphism and high on-clopidogrel platelet reactivity associated with adverse 1-year clinical outcome of elective percutaneous coronary intervention with drug-eluting or bare-metal stents
    • Trenk D, Hochholzer W, Fromm MF, et al. Cytochrome P450 2C19 681G>A polymorphism and high on-clopidogrel platelet reactivity associated with adverse 1-year clinical outcome of elective percutaneous coronary intervention with drug-eluting or bare-metal stents. J Am Coll Cardiol 2008; 51(20): 1925-34.
    • (2008) J Am Coll Cardiol , vol.51 , Issue.20 , pp. 1925-1934
    • Trenk, D.1    Hochholzer, W.2    Fromm, M.F.3
  • 130
    • 61349191612 scopus 로고    scopus 로고
    • Relation of cytochrome P450 2C19 loss-of-function polymorphism to occurrence of drug-eluting coronary stent thrombosis
    • Giusti B, Gori AM, Marcucci R, et al. Relation of cytochrome P450 2C19 loss-of-function polymorphism to occurrence of drug-eluting coronary stent thrombosis. Am J Cardiol 2009; 103(6): 806-11.
    • (2009) Am J Cardiol , vol.103 , Issue.6 , pp. 806-811
    • Giusti, B.1    Gori, A.M.2    Marcucci, R.3
  • 131
    • 84888116014 scopus 로고    scopus 로고
    • Routine assessment of on-clopidogrel platelet reactivity and gene polymorphisms in predicting clinical outcome following drugeluting stent implantation in patients with stable coronary artery disease
    • Viviani Anselmi C, Briguori C, Roncarati R, et al. Routine assessment of on-clopidogrel platelet reactivity and gene polymorphisms in predicting clinical outcome following drugeluting stent implantation in patients with stable coronary artery disease. JACC Cardiovasc Interv 2013; 6(11): 1166-75.
    • (2013) JACC Cardiovasc Interv , vol.6 , Issue.11 , pp. 1166-1175
    • Viviani, A.C.1    Briguori, C.2    Roncarati, R.3
  • 132
    • 38649131003 scopus 로고    scopus 로고
    • Biological effect of increased maintenance dose of clopidogrel in cardiovascular outpatients and influence of the cytochrome P450 2C19*2 allele on clopidogrel responsiveness
    • Fontana P, Senouf D, Mach F. Biological effect of increased maintenance dose of clopidogrel in cardiovascular outpatients and influence of the cytochrome P450 2C19*2 allele on clopidogrel responsiveness. Thromb Res 2008; 121(4): 463-8.
    • (2008) Thromb Res , vol.121 , Issue.4 , pp. 463-468
    • Fontana, P.1    Senouf, D.2    Mach, F.3
  • 133
    • 57549092687 scopus 로고    scopus 로고
    • The pharmacogenetics and pharmacodynamics of clopidogrel response: An analysis from the PRINC (Plavix Response in Coronary Intervention) trial
    • Gladding P, Webster M, Zeng I, et al. The pharmacogenetics and pharmacodynamics of clopidogrel response: an analysis from the PRINC (Plavix Response in Coronary Intervention) trial. JACC Cardiovasc Interv 2008; 1(6): 620-7.
    • (2008) JACC Cardiovasc Interv , vol.1 , Issue.6 , pp. 620-627
    • Gladding, P.1    Webster, M.2    Zeng, I.3
  • 134
    • 78049433100 scopus 로고    scopus 로고
    • Effects of CYP2C19 genotype on outcomes of clopidogrel treatment
    • Pare G, Mehta SR, Yusuf S, et al. Effects of CYP2C19 genotype on outcomes of clopidogrel treatment. N Engl J Med 2010; 363(18): 1704-14.
    • (2010) N Engl J Med , vol.363 , Issue.18 , pp. 1704-1714
    • Pare, G.1    Mehta, S.R.2    Yusuf, S.3
  • 135
    • 77958100874 scopus 로고    scopus 로고
    • Effect of CYP2C19 and ABCB1 single nucleotide polymorphisms on outcomes of treatment with ticagrelor versus clopidogrel for acute coronary syndromes: A genetic substudy of the PLATO trial
    • Wallentin L, James S, Storey RF, et al. Effect of CYP2C19 and ABCB1 single nucleotide polymorphisms on outcomes of treatment with ticagrelor versus clopidogrel for acute coronary syndromes: a genetic substudy of the PLATO trial. Lancet 2010; 376(9749): 1320-8.
    • (2010) Lancet , vol.376 , Issue.9749 , pp. 1320-1328
    • Wallentin, L.1    James, S.2    Storey, R.F.3
  • 136
    • 78049348037 scopus 로고    scopus 로고
    • Clopidogrel and the reduced-function CYP2C19 genetic variant: A limited piece of the overall therapeutic puzzle
    • Fuster V, Sweeny JM. Clopidogrel and the reduced-function CYP2C19 genetic variant: a limited piece of the overall therapeutic puzzle. JAMA 2010; 304(16): 1839-40.
    • (2010) JAMA , vol.304 , Issue.16 , pp. 1839-1840
    • Fuster, V.1    Sweeny, J.M.2
  • 138
    • 84883170442 scopus 로고    scopus 로고
    • Clinical Pharmacogenetics Implementation Consortium guidelines for CYP2C19 genotype and clopidogrel therapy: 2013 update
    • Scott SA, Sangkuhl K, Stein CM, et al. Clinical Pharmacogenetics Implementation Consortium guidelines for CYP2C19 genotype and clopidogrel therapy: 2013 update. Clin Pharmacol Ther 2013; 94(3): 317-23.
    • (2013) Clin Pharmacol Ther , vol.94 , Issue.3 , pp. 317-323
    • Scott, S.A.1    Sangkuhl, K.2    Stein, C.M.3
  • 139
    • 79960613122 scopus 로고    scopus 로고
    • Clinical Pharmacogenetics Implementation Consortium guidelines for cytochrome P450-2C19 (CYP2C19) genotype and clopidogrel therapy
    • Scott SA, Sangkuhl K, Gardner EE, et al. Clinical Pharmacogenetics Implementation Consortium guidelines for cytochrome P450-2C19 (CYP2C19) genotype and clopidogrel therapy. Clin Pharmacol Ther 2011; 90(2): 328-32.
    • (2011) Clin Pharmacol Ther , vol.90 , Issue.2 , pp. 328-332
    • Scott, S.A.1    Sangkuhl, K.2    Gardner, E.E.3
  • 140
    • 84883170442 scopus 로고    scopus 로고
    • Clinical pharmacogenetics implementation consortium guidelines for CYP2C19 genotype and clopidogrel therapy: 2013 update
    • Scott SA, Sangkuhl K, Stein CM, et al. Clinical pharmacogenetics implementation consortium guidelines for CYP2C19 genotype and clopidogrel therapy: 2013 update. Clin Pharmacol Ther 2013; 94(3): 317-23.
    • (2013) Clin Pharmacol Ther , vol.94 , Issue.3 , pp. 317-323
    • Scott, S.A.1    Sangkuhl, K.2    Stein, C.M.3
  • 141
    • 80054732393 scopus 로고    scopus 로고
    • The proton pump inhibitor, omeprazole, but not lansoprazole or pantoprazole, is a metabolism-dependent inhibitor of CYP2C19: Implications for coadministration with clopidogrel
    • Ogilvie BW, Yerino P, Kazmi F, et al. The proton pump inhibitor, omeprazole, but not lansoprazole or pantoprazole, is a metabolism-dependent inhibitor of CYP2C19: implications for coadministration with clopidogrel. Drug Metab Dispos 2011; 39(11): 2020-33.
    • (2011) Drug Metab Dispos , vol.39 , Issue.11 , pp. 2020-2033
    • Ogilvie, B.W.1    Yerino, P.2    Kazmi, F.3
  • 142
    • 3242676832 scopus 로고    scopus 로고
    • Comparison of inhibitory effects of the proton pump-inhibiting drugs omeprazole, esomeprazole, lansoprazole, pantoprazole, and rabeprazole on human cytochrome P450 activities
    • Li XQ, Andersson TB, Ahlstrom M, Weidolf L. Comparison of inhibitory effects of the proton pump-inhibiting drugs omeprazole, esomeprazole, lansoprazole, pantoprazole, and rabeprazole on human cytochrome P450 activities. Drug Metab Dispos 2004; 32(8): 821-7.
    • (2004) Drug Metab Dispos , vol.32 , Issue.8 , pp. 821-827
    • Li, X.Q.1    Andersson, T.B.2    Ahlstrom, M.3    Weidolf, L.4
  • 143
    • 12144275353 scopus 로고    scopus 로고
    • Clopidogrel versus aspirin and esomeprazole to prevent recurrent ulcer bleeding
    • Chan FK, Ching JY, Hung LC, et al. Clopidogrel versus aspirin and esomeprazole to prevent recurrent ulcer bleeding. N Engl J Med 2005; 352(3): 238-44.
    • (2005) N Engl J Med , vol.352 , Issue.3 , pp. 238-244
    • Chan, F.K.1    Ching, J.Y.2    Hung, L.C.3
  • 144
    • 56749183852 scopus 로고    scopus 로고
    • ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use: A report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents
    • Bhatt DL, Scheiman J, Abraham NS, et al. ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use: a report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents. Circulation 2008; 118(18): 1894-909.
    • (2008) Circulation , vol.118 , Issue.18 , pp. 1894-1909
    • Bhatt, D.L.1    Scheiman, J.2    Abraham, N.S.3
  • 145
    • 61949239030 scopus 로고    scopus 로고
    • Guidelines for prevention of NSAID-related ulcer complications
    • Practice Parameters Committee of the American College of G
    • Lanza FL, Chan FK, Quigley EM, Practice Parameters Committee of the American College of G. Guidelines for prevention of NSAID-related ulcer complications. Am J Gastroenterol 2009; 104(3): 728-38.
    • (2009) Am J Gastroenterol , vol.104 , Issue.3 , pp. 728-738
    • Lanza, F.L.1    Chan, F.K.2    Quigley, E.M.3
  • 146
    • 61549124132 scopus 로고    scopus 로고
    • Risk of adverse outcomes associated with concomitant use of clopidogrel and proton pump inhibitors following acute coronary syndrome
    • Ho PM, Maddox TM, Wang L, et al. Risk of adverse outcomes associated with concomitant use of clopidogrel and proton pump inhibitors following acute coronary syndrome. JAMA 2009; 301(9): 937-44.
    • (2009) JAMA , vol.301 , Issue.9 , pp. 937-944
    • Ho, P.M.1    Maddox, T.M.2    Wang, L.3
  • 147
    • 38349065084 scopus 로고    scopus 로고
    • Influence of omeprazole on the antiplatelet action of clopidogrel associated with aspirin: The randomized, double-blind OCLA (Omeprazole CLopidogrel Aspirin) study
    • Gilard M, Arnaud B, Cornily JC, et al. Influence of omeprazole on the antiplatelet action of clopidogrel associated with aspirin: the randomized, double-blind OCLA (Omeprazole CLopidogrel Aspirin) study. J Am Coll Cardiol 2008; 51(3): 256-60.
    • (2008) J Am Coll Cardiol , vol.51 , Issue.3 , pp. 256-260
    • Gilard, M.1    Arnaud, B.2    Cornily, J.C.3
  • 148
    • 78650517232 scopus 로고    scopus 로고
    • Differential effects of omeprazole and pantoprazole on the pharmacodynamics and pharmacokinetics of clopidogrel in healthy subjects: Randomized, placebo-controlled, crossover comparison studies
    • Angiolillo DJ, Gibson CM, Cheng S, et al. Differential effects of omeprazole and pantoprazole on the pharmacodynamics and pharmacokinetics of clopidogrel in healthy subjects: randomized, placebo-controlled, crossover comparison studies. Clin Pharmacol Ther 2011; 89(1): 65-74.
    • (2011) Clin Pharmacol Ther , vol.89 , Issue.1 , pp. 65-74
    • Angiolillo, D.J.1    Gibson, C.M.2    Cheng, S.3
  • 149
    • 0042859862 scopus 로고    scopus 로고
    • Adenosine diphosphate-induced platelet aggregation is associated with P2Y12 gene sequence variations in healthy subjects
    • Fontana P, Dupont A, Gandrille S, et al. Adenosine diphosphate-induced platelet aggregation is associated with P2Y12 gene sequence variations in healthy subjects. Circulation 2003;108(8):989-95.
    • (2003) Circulation , vol.108 , Issue.8 , pp. 989-995
    • Fontana, P.1    Dupont, A.2    Gandrille, S.3
  • 150
    • 0346365089 scopus 로고    scopus 로고
    • P2Y12 H2 haplotype is associated with peripheral arterial disease: A case-control study
    • Fontana P, Gaussem P, Aiach M, Fiessinger JN, Emmerich J, Reny JL. P2Y12 H2 haplotype is associated with peripheral arterial disease: a case-control study. Circulation 2003; 108(24): 2971-3.
    • (2003) Circulation , vol.108 , Issue.24 , pp. 2971-2973
    • Fontana, P.1    Gaussem, P.2    Aiach, M.3    Fiessinger, J.N.4    Emmerich, J.5    Reny, J.L.6
  • 151
    • 63149100441 scopus 로고    scopus 로고
    • Platelet reactivity and clopidogrel resistance are associated with the H2 haplotype of the P2Y12-ADP receptor gene
    • Staritz P, Kurz K, Stoll M, Giannitsis E, Katus HA, Ivandic BT. Platelet reactivity and clopidogrel resistance are associated with the H2 haplotype of the P2Y12-ADP receptor gene. International journal of cardiology. 2009; 133(3): 341-5.
    • (2009) International journal of cardiology. , vol.133 , Issue.3 , pp. 341-345
    • Staritz, P.1    Kurz, K.2    Stoll, M.3    Giannitsis, E.4    Katus, H.A.5    Ivandic, B.T.6
  • 152
    • 35748969344 scopus 로고    scopus 로고
    • Gene sequence variations of the platelet P2Y12 receptor are associated with coronary artery disease
    • Cavallari U, Trabetti E, Malerba G, et al. Gene sequence variations of the platelet P2Y12 receptor are associated with coronary artery disease. BMC Med Genet 2007; 8: 59.
    • (2007) BMC Med Genet , vol.8 , pp. 59
    • Cavallari, U.1    Trabetti, E.2    Malerba, G.3
  • 153
    • 84877578971 scopus 로고    scopus 로고
    • Polymorphisms of MDR1, CYP2C19 and P2Y12 genes in Indian population: Effects on clopidogrel response
    • Shalia KK, Shah VK, Pawar P, Divekar SS, Payannavar S. Polymorphisms of MDR1, CYP2C19 and P2Y12 genes in Indian population: effects on clopidogrel response. Indian Heart J 2013; 65(2): 158-67.
    • (2013) Indian Heart J , vol.65 , Issue.2 , pp. 158-167
    • Shalia, K.K.1    Shah, V.K.2    Pawar, P.3    Divekar, S.S.4    Payannavar, S.5
  • 154
    • 84879967780 scopus 로고    scopus 로고
    • P2Y12 receptor gene polymorphism and antiplatelet effect of clopidogrel in patients with coronary artery disease after coronary stenting
    • Zoheir N, Abd Elhamid S, Abulata N, El Sobky M, Khafagy D, Mostafa A. P2Y12 receptor gene polymorphism and antiplatelet effect of clopidogrel in patients with coronary artery disease after coronary stenting. Blood Coagul Fibrinolysis 2013; 24(5): 525-31.
    • (2013) Blood Coagul Fibrinolysis , vol.24 , Issue.5 , pp. 525-531
    • Zoheir, N.1    Abd Elhamid, S.2    Abulata, N.3    El Sobky, M.4    Khafagy, D.5    Mostafa, A.6
  • 155
    • 22044450322 scopus 로고    scopus 로고
    • Association of a functional polymorphism in the clopidogrel target receptor gene, P2Y12, and the risk for ischemic cerebrovascular events in patients with peripheral artery disease
    • Ziegler S, Schillinger M, Funk M, et al. Association of a functional polymorphism in the clopidogrel target receptor gene, P2Y12, and the risk for ischemic cerebrovascular events in patients with peripheral artery disease. Stroke 2005; 36(7): 1394-9.
    • (2005) Stroke , vol.36 , Issue.7 , pp. 1394-1399
    • Ziegler, S.1    Schillinger, M.2    Funk, M.3
  • 156
    • 41249099263 scopus 로고    scopus 로고
    • Purinergic receptor P2Y, G-protein coupled, 12 gene variants and risk of incident ischemic stroke, myocardial infarction, and venous thromboembolism
    • Zee RY, Michaud SE, Diehl KA, et al. Purinergic receptor P2Y, G-protein coupled, 12 gene variants and risk of incident ischemic stroke, myocardial infarction, and venous thromboembolism. Atherosclerosis 2008; 197(2): 694-9.
    • (2008) Atherosclerosis , vol.197 , Issue.2 , pp. 694-699
    • Zee, R.Y.1    Michaud, S.E.2    Diehl, K.A.3
  • 157
    • 24944465039 scopus 로고    scopus 로고
    • Lack of association between the P2Y12 receptor gene polymorphism and platelet response to clopidogrel in patients with coronary artery disease
    • Angiolillo DJ, Fernandez-Ortiz A, Bernardo E, et al. Lack of association between the P2Y12 receptor gene polymorphism and platelet response to clopidogrel in patients with coronary artery disease. Thromb Res 2005; 116(6): 491-7.
    • (2005) Thromb Res , vol.116 , Issue.6 , pp. 491-497
    • Angiolillo, D.J.1    Fernandez-Ortiz, A.2    Bernardo, E.3
  • 158
    • 79951677547 scopus 로고    scopus 로고
    • Very important pharmacogene summary: ABCB1 (MDR1, P-glycoprotein)
    • Hodges LM, Markova SM, Chinn LW, et al. Very important pharmacogene summary: ABCB1 (MDR1, P-glycoprotein). Pharmacogenet Genomics 2011; 21(3): 152-61.
    • (2011) Pharmacogenet Genomics , vol.21 , Issue.3 , pp. 152-161
    • Hodges, L.M.1    Markova, S.M.2    Chinn, L.W.3
  • 159
    • 33751080762 scopus 로고    scopus 로고
    • Impact of Pglycoprotein on clopidogrel absorption
    • Taubert D, von Beckerath N, Grimberg G, et al. Impact of Pglycoprotein on clopidogrel absorption. Clin Pharmacol Ther 2006; 80(5): 486-501.
    • (2006) Clin Pharmacol Ther , vol.80 , Issue.5 , pp. 486-501
    • Taubert, D.1    von Beckerath, N.2    Grimberg, G.3
  • 160
    • 12444273301 scopus 로고    scopus 로고
    • MDR1 genotyperelated duodenal absorption rate of digoxin in healthy Japanese subjects
    • Morita Y, Sakaeda T, Horinouchi M, et al. MDR1 genotyperelated duodenal absorption rate of digoxin in healthy Japanese subjects. Pharm Res 2003; 20(4): 552-6.
    • (2003) Pharm Res , vol.20 , Issue.4 , pp. 552-556
    • Morita, Y.1    Sakaeda, T.2    Horinouchi, M.3
  • 161
    • 0034724324 scopus 로고    scopus 로고
    • Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
    • Hoffmeyer S, Burk O, von Richter O, et al. Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo. Proc Natl Acad Sci U S A 2000; 97(7): 3473-8.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , Issue.7 , pp. 3473-3478
    • Hoffmeyer, S.1    Burk, O.2    von Richter, O.3
  • 162
    • 84867301073 scopus 로고    scopus 로고
    • ABCB1 C3435T polymorphism and response to clopidogrel treatment in coronary artery disease (CAD) patients: A meta-analysis
    • Su J, Xu J, Li X, et al. ABCB1 C3435T polymorphism and response to clopidogrel treatment in coronary artery disease (CAD) patients: a meta-analysis. PLoS One 2012; 7(10): e46366.
    • (2012) PLoS One , vol.7 , Issue.10
    • Su, J.1    Xu, J.2    Li, X.3
  • 163
    • 0038323843 scopus 로고    scopus 로고
    • Human MDR1 polymorphism: G2677T/A and C3435T have no effect on MDR1 transport activities
    • Morita N, Yasumori T, Nakayama K. Human MDR1 polymorphism: G2677T/A and C3435T have no effect on MDR1 transport activities. Biochem Pharmacol. 2003; 65(11): 1843-52.
    • (2003) Biochem Pharmacol. , vol.65 , Issue.11 , pp. 1843-1852
    • Morita, N.1    Yasumori, T.2    Nakayama, K.3
  • 164
    • 3042772026 scopus 로고    scopus 로고
    • Identification of functionally variant MDR1 alleles among European Americans and African Americans
    • Kim RB, Leake BF, Choo EF, et al. Identification of functionally variant MDR1 alleles among European Americans and African Americans. Clin Pharmacol Ther 2001; 70(2): 189-99.
    • (2001) Clin Pharmacol Ther , vol.70 , Issue.2 , pp. 189-199
    • Kim, R.B.1    Leake, B.F.2    Choo, E.F.3
  • 165
    • 33744501248 scopus 로고    scopus 로고
    • Exon sequencing and high resolution haplotype analysis of ABC transporter genes implicated in drug resistance
    • Leschziner G, Zabaneh D, Pirmohamed M, et al. Exon sequencing and high resolution haplotype analysis of ABC transporter genes implicated in drug resistance. Pharmacogenet Genomics 2006; 16(6): 439-50.
    • (2006) Pharmacogenet Genomics , vol.16 , Issue.6 , pp. 439-450
    • Leschziner, G.1    Zabaneh, D.2    Pirmohamed, M.3
  • 166
    • 80052626426 scopus 로고    scopus 로고
    • Anti-platelet therapy: Glycoprotein IIb-IIIa antagonists
    • Schneider DJ. Anti-platelet therapy: glycoprotein IIb-IIIa antagonists. Br J Clin Pharmacol 2011; 72(4): 672-82.
    • (2011) Br J Clin Pharmacol , vol.72 , Issue.4 , pp. 672-682
    • Schneider, D.J.1
  • 167
    • 0028940694 scopus 로고
    • On the structure and function of platelet integrin alpha IIb beta 3, the fibrinogen receptor
    • Calvete JJ. On the structure and function of platelet integrin alpha IIb beta 3, the fibrinogen receptor. Proc Soc Exp Biol Med 1995; 208(4): 346-60.
    • (1995) Proc Soc Exp Biol Med , vol.208 , Issue.4 , pp. 346-360
    • Calvete, J.J.1
  • 168
    • 0024531099 scopus 로고
    • Cellular adhesion: GPIIb-IIIa as a prototypic adhesion receptor
    • Plow EF, Ginsberg MH. Cellular adhesion: GPIIb-IIIa as a prototypic adhesion receptor. Prog Hemost Thromb 1989; 9: 117-56.
    • (1989) Prog Hemost Thromb , vol.9 , pp. 117-156
    • Plow, E.F.1    Ginsberg, M.H.2
  • 169
    • 0028609229 scopus 로고
    • Abciximab (c7E3 Fab). A review of its pharmacology and therapeutic potential in ischaemic heart disease
    • Faulds D, Sorkin EM. Abciximab (c7E3 Fab). A review of its pharmacology and therapeutic potential in ischaemic heart disease. Drugs 1994; 48(4): 583-98.
    • (1994) Drugs , vol.48 , Issue.4 , pp. 583-598
    • Faulds, D.1    Sorkin, E.M.2
  • 170
    • 63449116968 scopus 로고    scopus 로고
    • Chemical structures and mode of action of intravenous glycoprotein IIb/IIIa receptor blockers: A review
    • Hashemzadeh M, Furukawa M, Goldsberry S, Movahed MR. Chemical structures and mode of action of intravenous glycoprotein IIb/IIIa receptor blockers: A review. Exp Clin Cardiol 2008; 13(4): 192-7.
    • (2008) Exp Clin Cardiol , vol.13 , Issue.4 , pp. 192-197
    • Hashemzadeh, M.1    Furukawa, M.2    Goldsberry, S.3    Movahed, M.R.4
  • 171
    • 9144228045 scopus 로고    scopus 로고
    • A clinical trial of abciximab in elective percutaneous coronary intervention after pretreatment with clopidogrel
    • Kastrati A, Mehilli J, Schuhlen H, et al. A clinical trial of abciximab in elective percutaneous coronary intervention after pretreatment with clopidogrel. N Engl J Med 2004; 350(3): 232-8.
    • (2004) N Engl J Med , vol.350 , Issue.3 , pp. 232-238
    • Kastrati, A.1    Mehilli, J.2    Schuhlen, H.3
  • 172
    • 9644291514 scopus 로고    scopus 로고
    • Influence of treatment duration with a 600-mg dose of clopidogrel before percutaneous coronary revascularization
    • Kandzari DE, Berger PB, Kastrati A, et al. Influence of treatment duration with a 600-mg dose of clopidogrel before percutaneous coronary revascularization. J Am Coll Cardiol 2004; 44(11): 2133-6.
    • (2004) J Am Coll Cardiol , vol.44 , Issue.11 , pp. 2133-2136
    • Kandzari, D.E.1    Berger, P.B.2    Kastrati, A.3
  • 173
    • 32644447353 scopus 로고    scopus 로고
    • Clinical characteristics predict benefits from eptifibatide therapy during coronary stenting: Insights from the Enhanced Suppression of the Platelet IIb/IIIa Receptor With Integrilin Therapy (ESPRIT) trial
    • Puma JA, Banko LT, Pieper KS, et al. Clinical characteristics predict benefits from eptifibatide therapy during coronary stenting: insights from the Enhanced Suppression of the Platelet IIb/IIIa Receptor With Integrilin Therapy (ESPRIT) trial. J Am Coll Cardiol 2006; 47(4): 715-8.
    • (2006) J Am Coll Cardiol , vol.47 , Issue.4 , pp. 715-718
    • Puma, J.A.1    Banko, L.T.2    Pieper, K.S.3
  • 174
    • 0024588794 scopus 로고
    • The human platelet alloantigens, PlA1 and PlA2, are associated with a leucine33/proline33 amino acid polymorphism in membrane glycoprotein IIIa, and are distinguishable by DNA typing
    • Newman PJ, Derbes RS, Aster RH. The human platelet alloantigens, PlA1 and PlA2, are associated with a leucine33/proline33 amino acid polymorphism in membrane glycoprotein IIIa, and are distinguishable by DNA typing. J Clin Invest 1989; 83(5): 1778-81.
    • (1989) J Clin Invest , vol.83 , Issue.5 , pp. 1778-1781
    • Newman, P.J.1    Derbes, R.S.2    Aster, R.H.3
  • 176
    • 0036544668 scopus 로고    scopus 로고
    • Low incidence of paradoxical platelet activation by glycoprotein IIb/IIIa inhibitors
    • Weber AA, Meila D, Jacobs C, et al. Low incidence of paradoxical platelet activation by glycoprotein IIb/IIIa inhibitors. Thromb Res 2002; 106(1): 25-9.
    • (2002) Thromb Res , vol.106 , Issue.1 , pp. 25-29
    • Weber, A.A.1    Meila, D.2    Jacobs, C.3
  • 177
    • 0031834711 scopus 로고    scopus 로고
    • Structure and function of P-selectin glycoprotein ligand-1
    • Moore KL. Structure and function of P-selectin glycoprotein ligand-1. Leuk Lymphoma 1998; 29(1-2): 1-15.
    • (1998) Leuk Lymphoma , vol.29 , Issue.1-2 , pp. 1-15
    • Moore, K.L.1
  • 178
    • 1642634539 scopus 로고    scopus 로고
    • Role of platelet P-selectin and microparticle PSGL-1 in thrombus formation
    • Furie B, Furie BC. Role of platelet P-selectin and microparticle PSGL-1 in thrombus formation. Trends Mol Med 2004; 10(4): 171-8.
    • (2004) Trends Mol Med , vol.10 , Issue.4 , pp. 171-178
    • Furie, B.1    Furie, B.C.2
  • 179
    • 0033586430 scopus 로고    scopus 로고
    • Platelet glycoprotein IIIa polymorphism, aspirin, and thrombin generation
    • Undas A, Sanak M, Musial J, Szczeklik A. Platelet glycoprotein IIIa polymorphism, aspirin, and thrombin generation. Lancet 1999; 353(9157): 982-3.
    • (1999) Lancet , vol.353 , Issue.9157 , pp. 982-983
    • Undas, A.1    Sanak, M.2    Musial, J.3    Szczeklik, A.4
  • 180
    • 18244414272 scopus 로고    scopus 로고
    • Platelet GP IIIa Pl(A) polymorphisms display different sensitivities to agonists
    • Michelson AD, Furman MI, Goldschmidt-Clermont P, et al. Platelet GP IIIa Pl(A) polymorphisms display different sensitivities to agonists. Circulation 2000; 101(9): 1013-8.
    • (2000) Circulation , vol.101 , Issue.9 , pp. 1013-1018
    • Michelson, A.D.1    Furman, M.I.2    Goldschmidt-Clermont, P.3
  • 181
    • 0042735242 scopus 로고    scopus 로고
    • Resistance in vitro to low-dose aspirin is associated with platelet PlA1 (GP IIIa) polymorphism but not with C807T(GP Ia/IIa) and C-5T Kozak (GP Ibalpha) polymorphisms
    • Macchi L, Christiaens L, Brabant S, et al. Resistance in vitro to low-dose aspirin is associated with platelet PlA1 (GP IIIa) polymorphism but not with C807T(GP Ia/IIa) and C-5T Kozak (GP Ibalpha) polymorphisms. J Am Coll Cardiol 2003; 42(6): 1115-9.
    • (2003) J Am Coll Cardiol , vol.42 , Issue.6 , pp. 1115-1119
    • Macchi, L.1    Christiaens, L.2    Brabant, S.3
  • 182
    • 77952550106 scopus 로고    scopus 로고
    • The GPIIIa PlA polymorphism and the platelet hyperactivity in Tunisian patients with stable coronary artery disease treated with aspirin
    • Abderrazek F, Chakroun T, Addad F, et al. The GPIIIa PlA polymorphism and the platelet hyperactivity in Tunisian patients with stable coronary artery disease treated with aspirin. Thromb Res 2010; 125(6): e265-8.
    • (2010) Thromb Res , vol.125 , Issue.6
    • Abderrazek, F.1    Chakroun, T.2    Addad, F.3
  • 183
    • 67649522036 scopus 로고    scopus 로고
    • High loading dose of clopidogrel is unable to satisfactorily inhibit platelet reactivity in patients with glycoprotein IIIA gene polymorphism: A genetic substudy of PRAGUE-8 trial
    • Motovska Z, Widimsky P, Kvasnicka J, et al. High loading dose of clopidogrel is unable to satisfactorily inhibit platelet reactivity in patients with glycoprotein IIIA gene polymorphism: a genetic substudy of PRAGUE-8 trial. Blood Coagul Fibrinolysis 2009; 20(4): 257-62.
    • (2009) Blood Coagul Fibrinolysis , vol.20 , Issue.4 , pp. 257-262
    • Motovska, Z.1    Widimsky, P.2    Kvasnicka, J.3
  • 184
  • 185
    • 33845520623 scopus 로고    scopus 로고
    • Antithrombotic effects of aspirin based on PLA1/A2 glycoprotein IIIa polymorphism in patients with coronary artery disease
    • Dropinski J, Musial J, Sanak M, Wegrzyn W, Nizankowski R, Szczeklik A. Antithrombotic effects of aspirin based on PLA1/A2 glycoprotein IIIa polymorphism in patients with coronary artery disease. Thromb Res 2007; 119(3): 301-3.
    • (2007) Thromb Res , vol.119 , Issue.3 , pp. 301-303
    • Dropinski, J.1    Musial, J.2    Sanak, M.3    Wegrzyn, W.4    Nizankowski, R.5    Szczeklik, A.6
  • 186
    • 0015237292 scopus 로고
    • Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs
    • Vane JR. Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nat New Biol 1971; 231(25): 232-5.
    • (1971) Nat New Biol , vol.231 , Issue.25 , pp. 232-235
    • Vane, J.R.1
  • 187
    • 4444262310 scopus 로고    scopus 로고
    • Pharmacology and signaling of prostaglandin receptors: Multiple roles in inflammation and immune modulation
    • Hata AN, Breyer RM. Pharmacology and signaling of prostaglandin receptors: multiple roles in inflammation and immune modulation. Pharmacol Ther 2004; 103(2): 147-66.
    • (2004) Pharmacol Ther , vol.103 , Issue.2 , pp. 147-166
    • Hata, A.N.1    Breyer, R.M.2
  • 188
    • 0034105218 scopus 로고    scopus 로고
    • Effect of regulated expression of human cyclooxygenase isoforms on eicosanoid and isoeicosanoid production in inflammation
    • McAdam BF, Mardini IA, Habib A, et al. Effect of regulated expression of human cyclooxygenase isoforms on eicosanoid and isoeicosanoid production in inflammation. J Clin Invest 2000; 105(10): 1473-82.
    • (2000) J Clin Invest , vol.105 , Issue.10 , pp. 1473-1482
    • McAdam, B.F.1    Mardini, I.A.2    Habib, A.3
  • 189
    • 0034753651 scopus 로고    scopus 로고
    • Characterization of EP receptor subtypes responsible for prostaglandin E2-induced pain responses by use of EP1 and EP3 receptor knockout mice
    • Minami T, Nakano H, Kobayashi T, et al. Characterization of EP receptor subtypes responsible for prostaglandin E2-induced pain responses by use of EP1 and EP3 receptor knockout mice. Br J Pharmacol 2001; 133(3): 438-44.
    • (2001) Br J Pharmacol , vol.133 , Issue.3 , pp. 438-444
    • Minami, T.1    Nakano, H.2    Kobayashi, T.3
  • 190
    • 0031727033 scopus 로고    scopus 로고
    • Experimental models used to investigate the differential inhibition of cyclooxygenase-1 and cyclooxygenase-2 by non-steroidal anti-inflammatory drugs
    • Pairet M, van Ryn J. Experimental models used to investigate the differential inhibition of cyclooxygenase-1 and cyclooxygenase-2 by non-steroidal anti-inflammatory drugs. Inflamm Res 1998; 47 Suppl 2: S93-101.
    • (1998) Inflamm Res , vol.47 , Issue.SUPPL. 2
    • Pairet, M.1    van Ryn, J.2
  • 191
    • 0035425205 scopus 로고    scopus 로고
    • A three-step kinetic mechanism for selective inhibition of cyclooxygenase-2 by diarylheterocyclic inhibitors
    • Walker MC, Kurumbail RG, Kiefer JR, et al. A three-step kinetic mechanism for selective inhibition of cyclooxygenase-2 by diarylheterocyclic inhibitors. Biochemical J 2001; 357(Pt 3): 709-18.
    • (2001) Biochemical J , vol.357 , Issue.Pt 3 , pp. 709-718
    • Walker, M.C.1    Kurumbail, R.G.2    Kiefer, J.R.3
  • 192
    • 0030995430 scopus 로고    scopus 로고
    • Differential allosteric regulation of prostaglandin H synthase 1 and 2 by arachidonic acid
    • Swinney DC, Mak AY, Barnett J, Ramesha CS. Differential allosteric regulation of prostaglandin H synthase 1 and 2 by arachidonic acid. J Biol Chem 1997; 272(19): 12393-8.
    • (1997) J Biol Chem , vol.272 , Issue.19 , pp. 12393-12398
    • Swinney, D.C.1    Mak, A.Y.2    Barnett, J.3    Ramesha, C.S.4
  • 193
    • 0033575249 scopus 로고    scopus 로고
    • Hydroperoxide dependence and cooperative cyclooxygenase kinetics in prostaglandin H synthase-1 and-2
    • Chen W, Pawelek TR, Kulmacz RJ. Hydroperoxide dependence and cooperative cyclooxygenase kinetics in prostaglandin H synthase-1 and-2. J Biol Chem 1999; 274(29): 20301-6.
    • (1999) J Biol Chem , vol.274 , Issue.29 , pp. 20301-20306
    • Chen, W.1    Pawelek, T.R.2    Kulmacz, R.J.3
  • 194
    • 0027940487 scopus 로고
    • Biochemical and pharmacological characterization of the cyclooxygenase activity of human blood prostaglandin endoperoxide synthases
    • Patrignani P, Panara MR, Greco A, et al. Biochemical and pharmacological characterization of the cyclooxygenase activity of human blood prostaglandin endoperoxide synthases. J Pharmacol Exp Ther 1994; 271(3): 1705-12.
    • (1994) J Pharmacol Exp Ther , vol.271 , Issue.3 , pp. 1705-1712
    • Patrignani, P.1    Panara, M.R.2    Greco, A.3
  • 195
    • 0029911267 scopus 로고    scopus 로고
    • Flexibility of the NSAID binding site in the structure of human cyclooxygenase-2
    • Luong C, Miller A, Barnett J, Chow J, Ramesha C, Browner MF. Flexibility of the NSAID binding site in the structure of human cyclooxygenase-2. Nat Struct Biol 1996; 3(11): 927-33.
    • (1996) Nat Struct Biol , vol.3 , Issue.11 , pp. 927-933
    • Luong, C.1    Miller, A.2    Barnett, J.3    Chow, J.4    Ramesha, C.5    Browner, M.F.6
  • 196
    • 0028009093 scopus 로고
    • The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1
    • Picot D, Loll PJ, Garavito RM. The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1. Nature 1994; 367(6460): 243-9.
    • (1994) Nature , vol.367 , Issue.6460 , pp. 243-249
    • Picot, D.1    Loll, P.J.2    Garavito, R.M.3
  • 197
    • 0030461132 scopus 로고    scopus 로고
    • Structural basis for selective inhibition of cyclooxygenase-2 by antiinflammatory agents
    • Kurumbail RG, Stevens AM, Gierse JK, et al. Structural basis for selective inhibition of cyclooxygenase-2 by antiinflammatory agents. Nature 1996; 384(6610): 644-8.
    • (1996) Nature , vol.384 , Issue.6610 , pp. 644-648
    • Kurumbail, R.G.1    Stevens, A.M.2    Gierse, J.K.3
  • 198
    • 66349127141 scopus 로고    scopus 로고
    • Cyclooxygenases: Structural and functional insights
    • Rouzer CA, Marnett LJ. Cyclooxygenases: structural and functional insights. J Lipid Res 2009; 50 Suppl: S29-34.
    • (2009) J Lipid Res , vol.50 , Issue.SUPPL.
    • Rouzer, C.A.1    Marnett, L.J.2
  • 199
    • 0033791318 scopus 로고    scopus 로고
    • Cyclooxygenases: Structural, cellular, and molecular biology
    • Smith WL, DeWitt DL, Garavito RM. Cyclooxygenases: structural, cellular, and molecular biology. Annu Rev Biochem 2000; 69: 145-82.
    • (2000) Annu Rev Biochem , vol.69 , pp. 145-182
    • Smith, W.L.1    DeWitt, D.L.2    Garavito, R.M.3
  • 200
    • 0026075533 scopus 로고
    • Gastric cytoprotection by ornoprostil, a PGE1 analogue, in human subjects
    • Kobayashi K, Arakawa T, Higuchi K, Nakamura H. Gastric cytoprotection by ornoprostil, a PGE1 analogue, in human subjects. J Clin Gastroenterol 1991; 13 Suppl 1: S32-6.
    • (1991) J Clin Gastroenterol , vol.13 , Issue.SUPPL. 1
    • Kobayashi, K.1    Arakawa, T.2    Higuchi, K.3    Nakamura, H.4
  • 201
    • 0032744699 scopus 로고    scopus 로고
    • Impaired duodenal bicarbonate secretion and mucosal integrity in mice lacking prostaglandin E-receptor subtype EP(3)
    • Takeuchi K, Ukawa H, Kato S, et al. Impaired duodenal bicarbonate secretion and mucosal integrity in mice lacking prostaglandin E-receptor subtype EP(3). Gastroenterology 1999; 117(5): 1128-35.
    • (1999) Gastroenterology , vol.117 , Issue.5 , pp. 1128-1135
    • Takeuchi, K.1    Ukawa, H.2    Kato, S.3
  • 202
    • 46049093776 scopus 로고    scopus 로고
    • Gastric mucosal defense and cytoprotection: Bench to bedside
    • Laine L, Takeuchi K, Tarnawski A. Gastric mucosal defense and cytoprotection: bench to bedside. Gastroenterology 2008; 135(1): 41-60.
    • (2008) Gastroenterology , vol.135 , Issue.1 , pp. 41-60
    • Laine, L.1    Takeuchi, K.2    Tarnawski, A.3
  • 203
    • 0025005862 scopus 로고
    • The induction and suppression of prostaglandin H2 synthase (cyclooxygenase) in human monocytes
    • Fu JY, Masferrer JL, Seibert K, Raz A, Needleman P. The induction and suppression of prostaglandin H2 synthase (cyclooxygenase) in human monocytes. J Biol Chem 1990; 265(28): 16737-40.
    • (1990) J Biol Chem , vol.265 , Issue.28 , pp. 16737-16740
    • Fu, J.Y.1    Masferrer, J.L.2    Seibert, K.3    Raz, A.4    Needleman, P.5
  • 204
    • 0025754779 scopus 로고
    • Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing
    • Xie WL, Chipman JG, Robertson DL, Erikson RL, Simmons DL. Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing. Proc Natl Acad Sci U S A 1991; 88(7): 2692-6.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , Issue.7 , pp. 2692-2696
    • Xie, W.L.1    Chipman, J.G.2    Robertson, D.L.3    Erikson, R.L.4    Simmons, D.L.5
  • 205
    • 65249118795 scopus 로고    scopus 로고
    • The COXIB experience: A look in the rearview mirror
    • Marnett LJ. The COXIB experience: a look in the rearview mirror. Annu Rev Pharmacol Toxicol 2009; 49: 265-90.
    • (2009) Annu Rev Pharmacol Toxicol , vol.49 , pp. 265-290
    • Marnett, L.J.1
  • 206
    • 0028322893 scopus 로고
    • Selective inhibition of inducible cyclooxygenase 2 in vivo is antiinflammatory and nonulcerogenic
    • Masferrer JL, Zweifel BS, Manning PT, et al. Selective inhibition of inducible cyclooxygenase 2 in vivo is antiinflammatory and nonulcerogenic. Proc Natl Acad Sci U S A 1994; 91(8): 3228-32.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , Issue.8 , pp. 3228-3232
    • Masferrer, J.L.1    Zweifel, B.S.2    Manning, P.T.3
  • 207
    • 0031689543 scopus 로고    scopus 로고
    • Cyclooxygenase in biology and disease
    • Dubois RN, Abramson SB, Crofford L, et al. Cyclooxygenase in biology and disease. FASEB J 1998; 12(12): 1063-73.
    • (1998) FASEB J , vol.12 , Issue.12 , pp. 1063-1073
    • Dubois, R.N.1    Abramson, S.B.2    Crofford, L.3
  • 208
    • 0034707105 scopus 로고    scopus 로고
    • Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group
    • Bombardier C, Laine L, Reicin A, et al. Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group. N Engl J Med 2000; 343(21): 1520-8, 2 p following 8.
    • (2000) N Engl J Med , vol.343 , Issue.21 , pp. 1520-1528
    • Bombardier, C.1    Laine, L.2    Reicin, A.3
  • 209
    • 19744380776 scopus 로고    scopus 로고
    • Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trial
    • Bresalier RS, Sandler RS, Quan H, et al. Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trial. N Engl J Med 2005; 352(11): 1092-102.
    • (2005) N Engl J Med , vol.352 , Issue.11 , pp. 1092-1102
    • Bresalier, R.S.1    Sandler, R.S.2    Quan, H.3
  • 210
    • 0035934070 scopus 로고    scopus 로고
    • Risk of cardiovascular events associated with selective COX-2 inhibitors
    • Mukherjee D, Nissen SE, Topol EJ. Risk of cardiovascular events associated with selective COX-2 inhibitors. JAMA 2001; 286(8): 954-9.
    • (2001) JAMA , vol.286 , Issue.8 , pp. 954-959
    • Mukherjee, D.1    Nissen, S.E.2    Topol, E.J.3
  • 211
    • 9944262983 scopus 로고    scopus 로고
    • Risk of cardiovascular events and rofecoxib: Cumulative meta-analysis
    • Juni P, Nartey L, Reichenbach S, Sterchi R, Dieppe PA, Egger M. Risk of cardiovascular events and rofecoxib: cumulative meta-analysis. Lancet 2004; 364(9450): 2021-9.
    • (2004) Lancet , vol.364 , Issue.9450 , pp. 2021-2029
    • Juni, P.1    Nartey, L.2    Reichenbach, S.3    Sterchi, R.4    Dieppe, P.A.5    Egger, M.6
  • 212
    • 0034644396 scopus 로고    scopus 로고
    • Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis: The CLASS study: A randomized controlled trial. Celecoxib Long-term Arthritis Safety Study
    • Silverstein FE, Faich G, Goldstein JL, et al. Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis: the CLASS study: A randomized controlled trial. Celecoxib Long-term Arthritis Safety Study. JAMA 2000; 284(10): 1247-55.
    • (2000) JAMA , vol.284 , Issue.10 , pp. 1247-1255
    • Silverstein, F.E.1    Faich, G.2    Goldstein, J.L.3
  • 213
    • 20144365496 scopus 로고    scopus 로고
    • Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention
    • Solomon SD, McMurray JJ, Pfeffer MA, et al. Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention. N Engl J Med 2005; 352(11): 1071-80.
    • (2005) N Engl J Med , vol.352 , Issue.11 , pp. 1071-1080
    • Solomon, S.D.1    McMurray, J.J.2    Pfeffer, M.A.3
  • 214
    • 14944371100 scopus 로고    scopus 로고
    • Complications of the COX-2 inhibitors parecoxib and valdecoxib after cardiac surgery
    • Nussmeier NA, Whelton AA, Brown MT, et al. Complications of the COX-2 inhibitors parecoxib and valdecoxib after cardiac surgery. N Engl J Med 2005; 352(11): 1081-91.
    • (2005) N Engl J Med , vol.352 , Issue.11 , pp. 1081-1091
    • Nussmeier, N.A.1    Whelton, A.A.2    Brown, M.T.3
  • 215
    • 58749107157 scopus 로고    scopus 로고
    • Cardiovascular safety of the cyclooxygenase-2 selective inhibitors parecoxib and valdecoxib in the postoperative setting: An analysis of integrated data
    • Schug SA, Joshi GP, Camu F, Pan S, Cheung R. Cardiovascular safety of the cyclooxygenase-2 selective inhibitors parecoxib and valdecoxib in the postoperative setting: an analysis of integrated data. Anesth Analg 2009; 108(1): 299-307.
    • (2009) Anesth Analg , vol.108 , Issue.1 , pp. 299-307
    • Schug, S.A.1    Joshi, G.P.2    Camu, F.3    Pan, S.4    Cheung, R.5
  • 216
    • 33746344656 scopus 로고    scopus 로고
    • Clinical trial design and patient demographics of the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) study program: Cardiovascular outcomes with etoricoxib versus diclofenac in patients with osteoarthritis and rheumatoid arthritis
    • Cannon CP, Curtis SP, Bolognese JA, Laine L, Committee MS. Clinical trial design and patient demographics of the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) study program: cardiovascular outcomes with etoricoxib versus diclofenac in patients with osteoarthritis and rheumatoid arthritis. Am Heart J 2006; 152(2): 237-45.
    • (2006) Am Heart J , vol.152 , Issue.2 , pp. 237-245
    • Cannon, C.P.1    Curtis, S.P.2    Bolognese, J.A.3    Laine, L.4    Committee, M.S.5
  • 217
    • 33750944984 scopus 로고    scopus 로고
    • Cardiovascular outcomes with etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: A randomised comparison
    • Cannon CP, Curtis SP, FitzGerald GA, et al. Cardiovascular outcomes with etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparison. Lancet 2006; 368(9549): 1771-81.
    • (2006) Lancet , vol.368 , Issue.9549 , pp. 1771-1781
    • Cannon, C.P.1    Curtis, S.P.2    FitzGerald, G.A.3
  • 218
    • 33750934205 scopus 로고    scopus 로고
    • The ever growing story of cyclooxygenase inhibition
    • Rodriguez LA, Patrignani P. The ever growing story of cyclooxygenase inhibition. Lancet 2006; 368(9549): 1745-7.
    • (2006) Lancet , vol.368 , Issue.9549 , pp. 1745-1747
    • Rodriguez, L.A.1    Patrignani, P.2
  • 219
    • 34548105468 scopus 로고    scopus 로고
    • Risk of acute myocardial infarction with nonselective non-steroidal antiinflammatory drugs: A meta-analysis
    • Singh G, Wu O, Langhorne P, Madhok R. Risk of acute myocardial infarction with nonselective non-steroidal antiinflammatory drugs: a meta-analysis. Arthritis Res Ther 2006; 8(5): R153.
    • (2006) Arthritis Res Ther , vol.8 , Issue.5
    • Singh, G.1    Wu, O.2    Langhorne, P.3    Madhok, R.4
  • 221
    • 73649122841 scopus 로고    scopus 로고
    • Do COX-2 inhibitors raise blood pressure more than nonselective NSAIDs and placebo? An updated metaanalysis
    • Chan CC, Reid CM, Aw TJ, Liew D, Haas SJ, Krum H. Do COX-2 inhibitors raise blood pressure more than nonselective NSAIDs and placebo? An updated metaanalysis. J Hypertens 2009; 27(12): 2332-41.
    • (2009) J Hypertens , vol.27 , Issue.12 , pp. 2332-2341
    • Chan, C.C.1    Reid, C.M.2    Aw, T.J.3    Liew, D.4    Haas, S.J.5    Krum, H.6
  • 222
    • 33749337137 scopus 로고    scopus 로고
    • Adverse effects of cyclooxygenase 2 inhibitors on renal and arrhythmia events: Meta-analysis of randomized trials
    • Zhang J, Ding EL, Song Y. Adverse effects of cyclooxygenase 2 inhibitors on renal and arrhythmia events: meta-analysis of randomized trials. JAMA 2006; 296(13): 1619-32.
    • (2006) JAMA , vol.296 , Issue.13 , pp. 1619-1632
    • Zhang, J.1    Ding, E.L.2    Song, Y.3
  • 223
    • 3543044381 scopus 로고    scopus 로고
    • Relationship between COX-2 specific inhibitors and hypertension
    • Solomon DH, Schneeweiss S, Levin R, Avorn J. Relationship between COX-2 specific inhibitors and hypertension. Hypertension 2004; 44(2): 140-5.
    • (2004) Hypertension , vol.44 , Issue.2 , pp. 140-145
    • Solomon, D.H.1    Schneeweiss, S.2    Levin, R.3    Avorn, J.4
  • 224
    • 14844337012 scopus 로고    scopus 로고
    • Meta-analysis of cyclooxygenase-2 inhibitors and their effects on blood pressure
    • Aw TJ, Haas SJ, Liew D, Krum H. Meta-analysis of cyclooxygenase-2 inhibitors and their effects on blood pressure. Arch Intern Med 2005; 165(5): 490-6.
    • (2005) Arch Intern Med , vol.165 , Issue.5 , pp. 490-496
    • Aw, T.J.1    Haas, S.J.2    Liew, D.3    Krum, H.4
  • 225
    • 0035859802 scopus 로고    scopus 로고
    • Effects of selective cyclooxygenase-2 inhibition on vascular responses and thrombosis in canine coronary arteries
    • Hennan JK, Huang J, Barrett TD, et al. Effects of selective cyclooxygenase-2 inhibition on vascular responses and thrombosis in canine coronary arteries. Circulation 2001; 104(7): 820-5.
    • (2001) Circulation , vol.104 , Issue.7 , pp. 820-825
    • Hennan, J.K.1    Huang, J.2    Barrett, T.D.3
  • 226
    • 0037134011 scopus 로고    scopus 로고
    • Role of prostacyclin in the cardiovascular response to thromboxane A2
    • Cheng Y, Austin SC, Rocca B, et al. Role of prostacyclin in the cardiovascular response to thromboxane A2. Science 2002; 296(5567): 539-41.
    • (2002) Science , vol.296 , Issue.5567 , pp. 539-541
    • Cheng, Y.1    Austin, S.C.2    Rocca, B.3
  • 227
    • 0032948948 scopus 로고    scopus 로고
    • Effects of specific inhibition of cyclooxygenase-2 on sodium balance, hemodynamics, and vasoactive eicosanoids
    • Catella-Lawson F, McAdam B, Morrison BW, et al. Effects of specific inhibition of cyclooxygenase-2 on sodium balance, hemodynamics, and vasoactive eicosanoids. J Pharmacol Exp Ther 1999; 289(2): 735-41.
    • (1999) J Pharmacol Exp Ther , vol.289 , Issue.2 , pp. 735-741
    • Catella-Lawson, F.1    McAdam, B.2    Morrison, B.W.3
  • 228
    • 0033524421 scopus 로고    scopus 로고
    • Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: The human pharmacology of a selective inhibitor of COX-2
    • McAdam BF, Catella-Lawson F, Mardini IA, Kapoor S, Lawson JA, FitzGerald GA. Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: the human pharmacology of a selective inhibitor of COX-2. Proc Natl Acad Sci U S A 1999; 96(1): 272-7.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , Issue.1 , pp. 272-277
    • McAdam, B.F.1    Catella-Lawson, F.2    Mardini, I.A.3    Kapoor, S.4    Lawson, J.A.5    FitzGerald, G.A.6
  • 229
    • 0034702914 scopus 로고    scopus 로고
    • Cyclooxygenase-1 and-2-dependent prostacyclin formation in patients with atherosclerosis
    • Belton O, Byrne D, Kearney D, Leahy A, Fitzgerald DJ. Cyclooxygenase-1 and-2-dependent prostacyclin formation in patients with atherosclerosis. Circulation 2000; 102(8): 840-5.
    • (2000) Circulation , vol.102 , Issue.8 , pp. 840-845
    • Belton, O.1    Byrne, D.2    Kearney, D.3    Leahy, A.4    Fitzgerald, D.J.5
  • 230
    • 0021269059 scopus 로고
    • Increased prostacyclin biosynthesis in patients with severe atherosclerosis and platelet activation
    • FitzGerald GA, Smith B, Pedersen AK, Brash AR. Increased prostacyclin biosynthesis in patients with severe atherosclerosis and platelet activation. N Engl J Med 1984; 310(17): 1065-8.
    • (1984) N Engl J Med , vol.310 , Issue.17 , pp. 1065-1068
    • FitzGerald, G.A.1    Smith, B.2    Pedersen, A.K.3    Brash, A.R.4
  • 231
    • 0030816051 scopus 로고    scopus 로고
    • Altered pain perception and inflammatory response in mice lacking prostacyclin receptor
    • Murata T, Ushikubi F, Matsuoka T, et al. Altered pain perception and inflammatory response in mice lacking prostacyclin receptor. Nature 1997; 388(6643): 678-82.
    • (1997) Nature , vol.388 , Issue.6643 , pp. 678-682
    • Murata, T.1    Ushikubi, F.2    Matsuoka, T.3
  • 232
    • 0035975983 scopus 로고    scopus 로고
    • Roles of prostaglandin I(2) and thromboxane A(2) in cardiac ischemia-reperfusion injury: A study using mice lacking their respective receptors
    • Xiao CY, Hara A, Yuhki K, et al. Roles of prostaglandin I(2) and thromboxane A(2) in cardiac ischemia-reperfusion injury: a study using mice lacking their respective receptors. Circulation 2001; 104(18): 2210-5.
    • (2001) Circulation , vol.104 , Issue.18 , pp. 2210-2215
    • Xiao, C.Y.1    Hara, A.2    Yuhki, K.3
  • 233
    • 10344267004 scopus 로고    scopus 로고
    • COX-2-derived prostacyclin confers atheroprotection on female mice
    • Egan KM, Lawson JA, Fries S, et al. COX-2-derived prostacyclin confers atheroprotection on female mice. Science 2004; 306(5703): 1954-7.
    • (2004) Science , vol.306 , Issue.5703 , pp. 1954-1957
    • Egan, K.M.1    Lawson, J.A.2    Fries, S.3
  • 234
    • 0037013211 scopus 로고    scopus 로고
    • Impaired receptor binding and activation associated with a human prostacyclin receptor polymorphism
    • Stitham J, Stojanovic A, Hwa J. Impaired receptor binding and activation associated with a human prostacyclin receptor polymorphism. J Biol Chem 2002; 277(18): 15439-44.
    • (2002) J Biol Chem , vol.277 , Issue.18 , pp. 15439-15444
    • Stitham, J.1    Stojanovic, A.2    Hwa, J.3
  • 235
    • 42549150113 scopus 로고    scopus 로고
    • Acceleration of cardiovascular disease by a dysfunctional prostacyclin receptor mutation: Potential implications for cyclooxygenase-2 inhibition
    • Arehart E, Stitham J, Asselbergs FW, et al. Acceleration of cardiovascular disease by a dysfunctional prostacyclin receptor mutation: potential implications for cyclooxygenase-2 inhibition. Circ Res 2008; 102(8): 986-93.
    • (2008) Circ Res , vol.102 , Issue.8 , pp. 986-993
    • Arehart, E.1    Stitham, J.2    Asselbergs, F.W.3
  • 236
    • 53049083243 scopus 로고    scopus 로고
    • Differential association between human prostacyclin receptor polymorphisms and the development of venous thrombosis and intimal hyperplasia: A clinical biomarker study
    • Patrignani P, Di Febbo C, Tacconelli S, et al. Differential association between human prostacyclin receptor polymorphisms and the development of venous thrombosis and intimal hyperplasia: a clinical biomarker study. Pharmacogenet Genomics 2008; 18(7): 611-20.
    • (2008) Pharmacogenet Genomics , vol.18 , Issue.7 , pp. 611-620
    • Patrignani, P.1    Di Febbo, C.2    Tacconelli, S.3
  • 237
    • 77955984183 scopus 로고    scopus 로고
    • Dominant negative actions of human prostacyclin receptor variant through dimerization: Implications for cardiovascular disease
    • Ibrahim S, Tetruashvily M, Frey AJ, et al. Dominant negative actions of human prostacyclin receptor variant through dimerization: implications for cardiovascular disease. Arterioscler Thromb Vasc Biol 2010; 30(9): 1802-9.
    • (2010) Arterioscler Thromb Vasc Biol , vol.30 , Issue.9 , pp. 1802-1809
    • Ibrahim, S.1    Tetruashvily, M.2    Frey, A.J.3
  • 238
    • 79953208270 scopus 로고    scopus 로고
    • Comprehensive biochemical analysis of rare prostacyclin receptor variants: Study of association of signaling with coronary artery obstruction
    • Stitham J, Arehart E, Elderon L, et al. Comprehensive biochemical analysis of rare prostacyclin receptor variants: study of association of signaling with coronary artery obstruction. J Biol Chem 2011; 286(9): 7060-9.
    • (2011) J Biol Chem , vol.286 , Issue.9 , pp. 7060-7069
    • Stitham, J.1    Arehart, E.2    Elderon, L.3
  • 239
    • 84891881898 scopus 로고    scopus 로고
    • Effect of single nucleotide polymorphisms of the prostacyclin receptor gene on platelet activation in Japanese healthy subjects and patients with cerebral infarction
    • Shimizu M, Yoshimura S, Takizawa S, Kohara S, Inoko H, Takagi S. Effect of single nucleotide polymorphisms of the prostacyclin receptor gene on platelet activation in Japanese healthy subjects and patients with cerebral infarction. J Clin Neurosci 2013; 20(6): 851-6.
    • (2013) J Clin Neurosci , vol.20 , Issue.6 , pp. 851-856
    • Shimizu, M.1    Yoshimura, S.2    Takizawa, S.3    Kohara, S.4    Inoko, H.5    Takagi, S.6
  • 240
    • 30744469841 scopus 로고    scopus 로고
    • Evidence for purifying selection against synonymous mutations in mammalian exonic splicing enhancers
    • Parmley JL, Chamary JV, Hurst LD. Evidence for purifying selection against synonymous mutations in mammalian exonic splicing enhancers. Mol Biol Evol 2006; 23(2): 301-9.
    • (2006) Mol Biol Evol , vol.23 , Issue.2 , pp. 301-309
    • Parmley, J.L.1    Chamary, J.V.2    Hurst, L.D.3
  • 241
    • 33746435693 scopus 로고    scopus 로고
    • Preliminary assessment of the impact of microRNA-mediated regulation on coding sequence evolution in mammals
    • Hurst LD. Preliminary assessment of the impact of microRNA-mediated regulation on coding sequence evolution in mammals. J Mol Evol 2006; 63(2): 174-82.
    • (2006) J Mol Evol , vol.63 , Issue.2 , pp. 174-182
    • Hurst, L.D.1
  • 242
    • 35448992847 scopus 로고    scopus 로고
    • Silent polymorphisms speak: How they affect pharmacogenomics and the treatment of cancer
    • Sauna ZE, Kimchi-Sarfaty C, Ambudkar SV, Gottesman MM. Silent polymorphisms speak: how they affect pharmacogenomics and the treatment of cancer. Cancer Res 2007; 67(20): 9609-12.
    • (2007) Cancer Res , vol.67 , Issue.20 , pp. 9609-9612
    • Sauna, Z.E.1    Kimchi-Sarfaty, C.2    Ambudkar, S.V.3    Gottesman, M.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.