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Volumn 27, Issue 5, 2004, Pages 456-465

Aspirin resistance in cardiovascular disease: A review

Author keywords

Aspirin; Aspirin resistance; Platelet; Platelet aggregation inhibitors

Indexed keywords

ACETYLSALICYLIC ACID; ANTITHROMBOCYTIC AGENT; CLOPIDOGREL; TICLOPIDINE;

EID: 1942467385     PISSN: 10785884     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejvs.2003.12.025     Document Type: Review
Times cited : (54)

References (60)
  • 1
    • 0033561482 scopus 로고    scopus 로고
    • Prior aspirin use predicts worse outcomes in patients with non-ST-elevation acute coronary syndromes. PURSUIT Investigators. Platelet IIb/IIIa in Unstable angina: Receptor Suppression Using Integrilin Therapy
    • Alexander JH et al. Prior aspirin use predicts worse outcomes in patients with non-ST-elevation acute coronary syndromes. PURSUIT Investigators. Platelet IIb/IIIa in Unstable angina: Receptor Suppression Using Integrilin Therapy. Am J Cardiol 1999; 83: 1147-1151.
    • (1999) Am. J. Cardiol. , vol.83 , pp. 1147-1151
    • Alexander, J.H.1
  • 2
    • 0035421783 scopus 로고    scopus 로고
    • Profile and prevalence of aspirin resistance in patients with cardiovascular disease
    • Gum PA et al. Profile and prevalence of aspirin resistance in patients with cardiovascular disease. Am J Cardiol 2001; 88: 230-235.
    • (2001) Am. J. Cardiol. , vol.88 , pp. 230-235
    • Gum, P.A.1
  • 3
    • 0024298599 scopus 로고
    • Findings from the aspirin component of the ongoing Physicians' Health Study
    • Steering Committee of the Physicians' Health Study Research Group, Preliminary report
    • Steering Committee of the Physicians' Health Study Research Group, Preliminary report. Findings from the aspirin component of the ongoing Physicians' Health Study. N Engl J Med 1988; 318: 262-264.
    • (1988) N. Engl. J. Med. , vol.318 , pp. 262-264
  • 4
    • 0024406369 scopus 로고
    • Final report on the aspirin component of the ongoing Physicians' Health Study
    • Steering Committee of the Physicians' Health Study Research Group
    • Steering Committee of the Physicians' Health Study Research Group, Final report on the aspirin component of the ongoing Physicians' Health Study. N Engl J Med 1989; 321:129-135.
    • (1989) N. Engl. J. Med. , vol.321 , pp. 129-135
  • 5
    • 0023805341 scopus 로고
    • Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2
    • ISIS-2 (Second International Study of Infarct Survival) Collaborative Group
    • ISIS-2 (Second International Study of Infarct Survival) Collaborative Group, Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2. Lancet 1988; 2:349-360.
    • (1988) Lancet , vol.2 , pp. 349-360
  • 6
    • 0037065502 scopus 로고    scopus 로고
    • Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients
    • Antithrombotic Trialists' Collaboration
    • Antithrombotic Trialists' Collaboration, Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients. BMJ 2002; 324:71-86.
    • (2002) BMJ , vol.324 , pp. 71-86
  • 7
    • 0028128106 scopus 로고
    • Collaborative overview of randomised trials of antiplatelet therapy - II: Maintenance of vascular graft or arterial patency by antiplatelet therapy
    • Antiplatelet Trialists' Collaboration
    • Antiplatelet Trialists' Collaboration, Collaborative overview of randomised trials of antiplatelet therapy - II: maintenance of vascular graft or arterial patency by antiplatelet therapy. BMJ 1994; 308:159-168.
    • (1994) BMJ , vol.308 , pp. 159-168
  • 8
    • 0028120906 scopus 로고
    • Collaborative overview of randomised trials of antiplatelet therapy - I: Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients
    • Antiplatelet Trialists' Collaboration
    • Antiplatelet Trialists' Collaboration, Collaborative overview of randomised trials of antiplatelet therapy - I: prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients. BMJ 1994; 308:81-106.
    • (1994) BMJ , vol.308 , pp. 81-106
  • 9
    • 0031430230 scopus 로고    scopus 로고
    • X-ray crystallographic study of the structure of prostaglandin H synthase
    • Picot D, Loll PJ, Garavito RM. X-ray crystallographic study of the structure of prostaglandin H synthase. Adv Exp Med Biol 1997; 400A:107-111.
    • (1997) Adv. Exp. Med. Biol. , vol.400 A , pp. 107-111
    • Picot, D.1    Loll, P.J.2    Garavito, R.M.3
  • 10
    • 0030010696 scopus 로고    scopus 로고
    • Synthesis and use of iodinated nonsteroidal antiinflammatory drug analogs as crystallographic probes of the prostaglandin H2 synthase cyclooxygenase active site
    • Loll PJ, Picot D, Ekabo O, Garavito RM. Synthesis and use of iodinated nonsteroidal antiinflammatory drug analogs as crystallographic probes of the prostaglandin H2 synthase cyclooxygenase active site. Biochemistry (Mosc) 1996; 35:7330-7340.
    • (1996) Biochemistry (Mosc) , vol.35 , pp. 7330-7340
    • Loll, P.J.1    Picot, D.2    Ekabo, O.3    Garavito, R.M.4
  • 11
    • 0003132992 scopus 로고    scopus 로고
    • Clopidogrel: An antithrombotic drug acting on the ADP dependent pathway of human platelets
    • Reference Type: Generic
    • Savi P, Heilmann E, Nurden P et al. Clopidogrel: an antithrombotic drug acting on the ADP dependent pathway of human platelets. Clin Appl Thromb Hemost 1996; 2:35-42. Reference Type: Generic.
    • (1996) Clin. Appl. Thromb. Hemost. , vol.2 , pp. 35-42
    • Savi, P.1    Heilmann, E.2    Nurden, P.3
  • 12
    • 0028182694 scopus 로고
    • Binding of [3H]-2-methylthio ADP to rat platelets - Effect of clopidogrel and ticlopidine
    • Savi P, Laplace MC, Maffrand JP, Herbert JM. Binding of [3H]-2-methylthio ADP to rat platelets - effect of clopidogrel and ticlopidine. J Pharmacol Exp Ther 1994; 269:772-777.
    • (1994) J. Pharmacol. Exp. Ther. , vol.269 , pp. 772-777
    • Savi, P.1    Laplace, M.C.2    Maffrand, J.P.3    Herbert, J.M.4
  • 13
    • 0027436408 scopus 로고
    • Efficacy of ticlopidine and aspirin for prevention of reversible cerebrovascular ischemic events. The ticlopidine aspirin stroke study
    • Bellavance A. Efficacy of ticlopidine and aspirin for prevention of reversible cerebrovascular ischemic events. The ticlopidine aspirin stroke study. Stroke 1993; 24:1452-1457.
    • (1993) Stroke , vol.24 , pp. 1452-1457
    • Bellavance, A.1
  • 14
    • 0030590746 scopus 로고    scopus 로고
    • A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE)
    • CAPRIE Steering Committee
    • CAPRIE Steering Committee, A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE). Lancet 1996; 348:1329-1339.
    • (1996) Lancet , vol.348 , pp. 1329-1339
  • 15
    • 0035899289 scopus 로고    scopus 로고
    • Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation
    • Yusuf S et al. Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation. N Engl J Med 2001; 345:494-502.
    • (2001) N. Engl. J. Med. , vol.345 , pp. 494-502
    • Yusuf, S.1
  • 16
  • 18
    • 0037101578 scopus 로고    scopus 로고
    • Resistance to aspirin in vitro is associated with increased platelet sensitivity to adenosine diphosphate
    • Macchi L et al. Resistance to aspirin in vitro is associated with increased platelet sensitivity to adenosine diphosphate. Thromb Res 2003; 107:45-49.
    • (2003) Thromb. Res. , vol.107 , pp. 45-49
    • Macchi, L.1
  • 19
    • 0037046196 scopus 로고    scopus 로고
    • Aspirin-resistant thromboxane biosynthesis and the risk of myocardial infarction, stroke, or cardiovascular death in patients at high risk for cardiovascular events
    • Eikelboom JW et al. Aspirin-resistant thromboxane biosynthesis and the risk of myocardial infarction, stroke, or cardiovascular death in patients at high risk for cardiovascular events. Circulation 2002; 105:1650-1655.
    • (2002) Circulation , vol.105 , pp. 1650-1655
    • Eikelboom, J.W.1
  • 21
    • 0027970934 scopus 로고
    • Development of aspirin resistance in persons with previous ischemic stroke
    • Helgason CM et al. Development of aspirin resistance in persons with previous ischemic stroke. Stroke 1994; 25:2331-2336.
    • (1994) Stroke , vol.25 , pp. 2331-2336
    • Helgason, C.M.1
  • 22
    • 0028934985 scopus 로고
    • Individual variation in the effects of ASA on platelet function: Implications for the use of ASA clinically
    • Buchanan MR, Brister SJ. Individual variation in the effects of ASA on platelet function: implications for the use of ASA clinically. Can J Cardiol 1995; 11:221-227.
    • (1995) Can. J. Cardiol. , vol.11 , pp. 221-227
    • Buchanan, M.R.1    Brister, S.J.2
  • 23
    • 0028050259 scopus 로고
    • Population variability in the effect of aspirin on platelet function. Implications for clinical trials and therapy
    • Pappas JM, Westengard JC, Bull BS. Population variability in the effect of aspirin on platelet function. Implications for clinical trials and therapy. Arch Pathol Lab Med 1994; 118:801-804.
    • (1994) Arch. Pathol. Lab. Med. , vol.118 , pp. 801-804
    • Pappas, J.M.1    Westengard, J.C.2    Bull, B.S.3
  • 24
    • 0025997575 scopus 로고
    • Effects of acetylsalicylic acid in stroke patients. Evidence of nonresponders in a subpopulation of treated patients
    • Grotemeyer KH. Effects of acetylsalicylic acid in stroke patients. Evidence of nonresponders in a subpopulation of treated patients. Thromb Res 1991; 63:587-593.
    • (1991) Thromb. Res. , vol.63 , pp. 587-593
    • Grotemeyer, K.H.1
  • 25
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis - An inflammatory disease
    • Ross R. Atherosclerosis - an inflammatory disease. N Engl J Med 1999; 340:115-126.
    • (1999) N. Engl. J. Med. , vol.340 , pp. 115-126
    • Ross, R.1
  • 26
    • 9844224482 scopus 로고    scopus 로고
    • Variable platelet response to low-dose ASA and the risk of limb deterioration in patients submitted to peripheral arterial angioplasty
    • Mueller MR et al. Variable platelet response to low-dose ASA and the risk of limb deterioration in patients submitted to peripheral arterial angioplasty. Thromb Haemost 1997; 78: 1003-1007.
    • (1997) Thromb. Haemost. , vol.78 , pp. 1003-1007
    • Mueller, M.R.1
  • 27
    • 0027287766 scopus 로고
    • The epidemiology of peripheral arterial disease
    • Leng GC, Fowkes FGR. The epidemiology of peripheral arterial disease. Vasc Med Rev 1993; 4:5-18.
    • (1993) Vasc. Med. Rev. , vol.4 , pp. 5-18
    • Leng, G.C.1    Fowkes, F.G.R.2
  • 28
    • 0028828489 scopus 로고
    • Cigarette smoking acutely increases platelet thrombus formation in patients with coronary artery disease taking aspirin
    • Hung J, Lam JY, Lacoste L, Letchacovski G. Cigarette smoking acutely increases platelet thrombus formation in patients with coronary artery disease taking aspirin. Circulation 1995; 92: 2432-2436.
    • (1995) Circulation , vol.92 , pp. 2432-2436
    • Hung, J.1    Lam, J.Y.2    Lacoste, L.3    Letchacovski, G.4
  • 29
    • 0034702914 scopus 로고    scopus 로고
    • Cyclooxygenase-1 and -2-dependent prostacyclin formation in patients with atherosclerosis
    • Belton O, Byrne D, Kearney D, Leahy A, Fitzgerald DJ. Cyclooxygenase-1 and -2-dependent prostacyclin formation in patients with atherosclerosis. Circulation 2000; 102:840-845.
    • (2000) Circulation , vol.102 , pp. 840-845
    • Belton, O.1    Byrne, D.2    Kearney, D.3    Leahy, A.4    Fitzgerald, D.J.5
  • 31
    • 0037046174 scopus 로고    scopus 로고
    • Why are some individuals resistant to the cardioprotective effects of aspirin? Could it be thromboxane A2?
    • Halushka MK, Halushka PV. Why are some individuals resistant to the cardioprotective effects of aspirin? Could it be thromboxane A2? Circulation 2002; 105:1620-1622.
    • (2002) Circulation , vol.105 , pp. 1620-1622
    • Halushka, M.K.1    Halushka, P.V.2
  • 32
    • 0025776841 scopus 로고
    • Erythrocytes metabolically enhance collagen-induced platelet responsiveness via increased thromboxane production, adenosine diphosphate release, and recruitment
    • Valles J et al. Erythrocytes metabolically enhance collagen-induced platelet responsiveness via increased thromboxane production, adenosine diphosphate release, and recruitment. Blood 1991; 78:154-162.
    • (1991) Blood , vol.78 , pp. 154-162
    • Valles, J.1
  • 33
    • 0031013712 scopus 로고    scopus 로고
    • Prothrombotic effects of erythrocytes on platelet reactivity. Reduction by aspirin
    • Santos MT et al. Prothrombotic effects of erythrocytes on platelet reactivity. Reduction by aspirin. Circulation 1997; 95:63-68.
    • (1997) Circulation , vol.95 , pp. 63-68
    • Santos, M.T.1
  • 34
    • 0035960620 scopus 로고    scopus 로고
    • P1(A2) polymorphism of beta(3) integrins is associated with enhanced thrombin generation and impaired antithrombotic action of aspirin at the site of microvascular injury
    • Undas A, Brummel K, Musial J, Mann KG, Szczeklik A. P1(A2) polymorphism of beta(3) integrins is associated with enhanced thrombin generation and impaired antithrombotic action of aspirin at the site of microvascular injury. Circulation 2001; 104: 2666-2672.
    • (2001) Circulation , vol.104 , pp. 2666-2672
    • Undas, A.1    Brummel, K.2    Musial, J.3    Mann, K.G.4    Szczeklik, A.5
  • 35
    • 0032079569 scopus 로고    scopus 로고
    • Inherited platelet glycoprotein polymorphisms and a risk for coronary heart disease in young Central Europeans
    • Sperr W, Huber K, Roden M. Inherited platelet glycoprotein polymorphisms and a risk for coronary heart disease in young Central Europeans. Thromb Res 1998; 90:117-123.
    • (1998) Thromb. Res. , vol.90 , pp. 117-123
    • Sperr, W.1    Huber, K.2    Roden, M.3
  • 36
    • 0034730075 scopus 로고    scopus 로고
    • Oxidant stress and aspirin-insensitive thromboxane biosynthesis in severe unstable angina
    • Cipollone F et al. Oxidant stress and aspirin-insensitive thromboxane biosynthesis in severe unstable angina. Circulation 2000; 102:1007-1013.
    • (2000) Circulation , vol.102 , pp. 1007-1013
    • Cipollone, F.1
  • 37
    • 0034054309 scopus 로고    scopus 로고
    • Increased platelet sensitivity to collagen in individuals resistant to low-dose aspirin
    • Kawasaki T, Ozeki Y, Igawa T, Kambayashi J. Increased platelet sensitivity to collagen in individuals resistant to low-dose aspirin. Stroke 2000; 31:591-595.
    • (2000) Stroke , vol.31 , pp. 591-595
    • Kawasaki, T.1    Ozeki, Y.2    Igawa, T.3    Kambayashi, J.4
  • 38
    • 18744402157 scopus 로고    scopus 로고
    • Aspirin resistance after coronary artery bypass grafting
    • Zimmermann N et al. Aspirin resistance after coronary artery bypass grafting. J Thorac Cardiovasc Surg 2001; 121:982-984.
    • (2001) J. Thorac. Cardiovasc. Surg. , vol.121 , pp. 982-984
    • Zimmermann, N.1
  • 39
    • 0031666908 scopus 로고    scopus 로고
    • The effect of different antithrombotic regimens on platelet aggregation after myocardial infarction
    • Hurlen M, Seljeflot I, Arnesen H. The effect of different antithrombotic regimens on platelet aggregation after myocardial infarction. Scand Cardiovasc J 1998; 32:233-237.
    • (1998) Scand. Cardiovasc. J. , vol.32 , pp. 233-237
    • Hurlen, M.1    Seljeflot, I.2    Arnesen, H.3
  • 40
    • 0034781382 scopus 로고    scopus 로고
    • Effects of combining three different antiplatelet agents on platelets and leukocytes in whole blood in vitro
    • Zhao L, Bath P, Heptinstall S. Effects of combining three different antiplatelet agents on platelets and leukocytes in whole blood in vitro. Br J Pharmacol 2001; 134:353-358.
    • (2001) Br. J. Pharmacol. , vol.134 , pp. 353-358
    • Zhao, L.1    Bath, P.2    Heptinstall, S.3
  • 41
    • 0036826025 scopus 로고    scopus 로고
    • Aspirin non-responsiveness as measured by PFA-100 in patients with coronary artery disease
    • Andersen K, Hurlen M, Arnesen H, Seljeflot I. Aspirin non-responsiveness as measured by PFA-100 in patients with coronary artery disease. Thromb Res 2003; 108:37-42.
    • (2003) Thromb. Res. , vol.108 , pp. 37-42
    • Andersen, K.1    Hurlen, M.2    Arnesen, H.3    Seljeflot, I.4
  • 42
    • 0031596559 scopus 로고    scopus 로고
    • PFA-100 system: A new method for assessment of platelet dysfunction
    • Mammen EF et al. PFA-100 system: a new method for assessment of platelet dysfunction. Semin Thromb Hemost 1998; 24:195-202.
    • (1998) Semin. Thromb. Hemost. , vol.24 , pp. 195-202
    • Mammen, E.F.1
  • 43
    • 0027240186 scopus 로고
    • Control of the circulation by endothelial mediators. Inaugural G.B. West Memorial Lecture
    • Vane J. Control of the circulation by endothelial mediators. Inaugural G.B. West Memorial Lecture. Int Arch Allergy Immunol 1993; 101:333-345.
    • (1993) Int. Arch. Allergy Immunol. , vol.101 , pp. 333-345
    • Vane, J.1
  • 44
    • 0031596559 scopus 로고    scopus 로고
    • PFA-100 system: A new method for assessment of platelet dysfunction
    • Mammen EF et al. PFA-100 system: a new method for assessment of platelet dysfunction. Semin Thromb Hemost 1998; 24:195-202.
    • (1998) Semin. Thromb. Hemost. , vol.24 , pp. 195-202
    • Mammen, E.F.1
  • 45
    • 0033960903 scopus 로고    scopus 로고
    • Monitoring of aspirin (ASA) pharmacodynamics with the platelet function analyzer PFA-100
    • Homoncik M et al. Monitoring of aspirin (ASA) pharmacodynamics with the platelet function analyzer PFA-100. Thromb Haemost 2000; 83:316-321.
    • (2000) Thromb. Haemost. , vol.83 , pp. 316-321
    • Homoncik, M.1
  • 46
    • 0036825956 scopus 로고    scopus 로고
    • PFA-100™ and flow cytometry: Can they challenge aggregometry to assess antiplatelet agents, other than GPIIbIIIa blockers, in coronary angioplasty?
    • Hézard N et al. PFA-100™ and flow cytometry: can they challenge aggregometry to assess antiplatelet agents, other than GPIIbIIIa blockers, in coronary angioplasty? Thromb Res 2003; 108:43-47.
    • (2003) Thromb. Res. , vol.108 , pp. 43-47
    • Hézard, N.1
  • 47
    • 12244255075 scopus 로고    scopus 로고
    • Effect of a single dose aspirin on platelets in humans with multiple risk factors for coronary artery disease
    • Malinin AI, Atar D, Callahan KP, McKenzie ME, Serebruany VL. Effect of a single dose aspirin on platelets in humans with multiple risk factors for coronary artery disease. Eur J Pharmacol 2003; 462:139-143.
    • (2003) Eur. J. Pharmacol. , vol.462 , pp. 139-143
    • Malinin, A.I.1    Atar, D.2    Callahan, K.P.3    McKenzie, M.E.4    Serebruany, V.L.5
  • 49
    • 0035124920 scopus 로고    scopus 로고
    • Platelet-active drugs: The relationships among dose, effectiveness, and side effects
    • Patrono C et al. Platelet-active drugs: the relationships among dose, effectiveness, and side effects. Chest 2001; 119:39S-63S.
    • (2001) Chest , vol.119
    • Patrono, C.1
  • 50
    • 0023831892 scopus 로고
    • United Kingdom transient ischaemic attack (UK-TIA) aspirin trial: Interim results
    • UK-TIA Study Group
    • UK-TIA Study Group, United Kingdom transient ischaemic attack (UK-TIA) aspirin trial: interim results. Br Med J (Clin Res Ed) 1988; 296:316-320.
    • (1988) Br. Med. J. (Clin Res Ed) , vol.296 , pp. 316-320
  • 51
    • 0026355123 scopus 로고
    • The United Kingdom transient ischaemic attack (UK-TIA) aspirin trial: Final results
    • Farrell B, Godwin J, Richards S, Warlow C. The United Kingdom transient ischaemic attack (UK-TIA) aspirin trial: final results. J Neurol Neurosurg Psychiatry 1991; 54:1044-1054.
    • (1991) J. Neurol. Neurosurg. Psychiatry , vol.54 , pp. 1044-1054
    • Farrell, B.1    Godwin, J.2    Richards, S.3    Warlow, C.4
  • 52
    • 0030752399 scopus 로고    scopus 로고
    • Effect of aspirin dosage and enteric coating on platelet reactivity
    • Feng D et al. Effect of aspirin dosage and enteric coating on platelet reactivity. Am J Cardiol 1997; 80:189-193.
    • (1997) Am. J. Cardiol. , vol.80 , pp. 189-193
    • Feng, D.1
  • 53
    • 0038370082 scopus 로고    scopus 로고
    • Aspirin dosage and thromboxane synthesis in patients with vascular disease
    • Hart RG et al. Aspirin dosage and thromboxane synthesis in patients with vascular disease. Pharmacotherapy 2003; 23:579-584.
    • (2003) Pharmacotherapy , vol.23 , pp. 579-584
    • Hart, R.G.1
  • 54
    • 0028288681 scopus 로고
    • Norepinephrine-induced human platelet activation in vivo is only partly counteracted by aspirin
    • Larsson PT, Wallen NH, Hjemdahl P. Norepinephrine-induced human platelet activation in vivo is only partly counteracted by aspirin. Circulation 1994; 89:1951-1957.
    • (1994) Circulation , vol.89 , pp. 1951-1957
    • Larsson, P.T.1    Wallen, N.H.2    Hjemdahl, P.3
  • 55
    • 0344931802 scopus 로고    scopus 로고
    • Evidence for prothrombotic effects of exercise and limited protection by aspirin
    • Li N, Wallen NH, Hjemdahl P. Evidence for prothrombotic effects of exercise and limited protection by aspirin. Circulation 1999; 100:1374-1379.
    • (1999) Circulation , vol.100 , pp. 1374-1379
    • Li, N.1    Wallen, N.H.2    Hjemdahl, P.3
  • 56
    • 0034283498 scopus 로고    scopus 로고
    • Increased platelet aggregability during exercise in patients with previous myocardial infarction. Lack of inhibition by aspirin
    • Hurlen M, Seljeflot I, Arnesen H. Increased platelet aggregability during exercise in patients with previous myocardial infarction. Lack of inhibition by aspirin. Thromb Res 2000; 99: 487-494.
    • (2000) Thromb. Res. , vol.99 , pp. 487-494
    • Hurlen, M.1    Seljeflot, I.2    Arnesen, H.3
  • 57
    • 0036878918 scopus 로고    scopus 로고
    • Resistance to aspirin in vitro at rest and during exercise in patients with angiographically proven coronary artery disease
    • Christiaens L et al. Resistance to aspirin in vitro at rest and during exercise in patients with angiographically proven coronary artery disease. Thromb Res 2002;.
    • (2002) Thromb. Res.
    • Christiaens, L.1
  • 58
    • 0037454168 scopus 로고    scopus 로고
    • A prospective blinded determination of the natural history of aspirin resistance among stable patients with cardiovascular disease
    • Gum PA, Kottke-Marchant K, Welsh P, White J, Topol EJ. A prospective blinded determination of the natural history of aspirin resistance among stable patients with cardiovascular disease. J Am Coll Cardiol 2003; 41:961-965.
    • (2003) J. Am. Coll. Cardiol. , vol.41 , pp. 961-965
    • Gum, P.A.1    Kottke-Marchant, K.2    Welsh, P.3    White, J.4    Topol, E.J.5
  • 59
    • 0037276966 scopus 로고    scopus 로고
    • Aspirin non-responder status in patients with recurrent cerebral ischemic attacks
    • Grundmann K, Jaschonek K, Kleine B, Dichgans J, Topka H. Aspirin non-responder status in patients with recurrent cerebral ischemic attacks. J Neurol 2003; 250:63-66.
    • (2003) J. Neurol. , vol.250 , pp. 63-66
    • Grundmann, K.1    Jaschonek, K.2    Kleine, B.3    Dichgans, J.4    Topka, H.5
  • 60
    • 0034511771 scopus 로고    scopus 로고
    • Results of the BRAT study - A pilot study investigating the possible significance of ASA non-responsiveness on the benefits and risks of ASA on thrombosis in patients undergoing coronary artery bypass surgery
    • Buchanan MR et al. Results of the BRAT study - a pilot study investigating the possible significance of ASA non-responsiveness on the benefits and risks of ASA on thrombosis in patients undergoing coronary artery bypass surgery. Can J Cardiol 2000; 16:1385-1390.
    • (2000) Can. J. Cardiol. , vol.16 , pp. 1385-1390
    • Buchanan, M.R.1


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