Cytochrome 2c19*17 allelic variant, platelet aggregation, bleeding events, and stent thrombosis in clopidogrel-treated patients with coronary stent placement

Circulation

Volumn 121, Issue 4, 2010, Pages 512-518

  Sibbing, Dirk ^a   Koch, Werner ^a   Gebhard, Daniela ^a   Schuster, Tibor ^b   Braun, Siegmund ^a   Stegherr, Julia ^a   Morath, Tanja ^a   Schömig, Albert ^a   Von Beckerath, Nicolas ^a   Kastrati, Adnan ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Bleeding; Clopidogrel; CYP2C19; Cytochrome; Stent thrombosis

Indexed keywords

ABCIXIMAB; ACETYLSALICYLIC ACID; ADENOSINE DIPHOSPHATE; CLOPIDOGREL; CYTOCHROME P450 2C19; HEPARIN; ANTITHROMBOCYTIC AGENT; CYP2C19 PROTEIN, HUMAN; DRUG DERIVATIVE; TICLOPIDINE; UNSPECIFIC MONOOXYGENASE;

ADULT; AGED; ANTICOAGULANT THERAPY; ARTICLE; BLEEDING; CLINICAL TRIAL; CORONARY STENT; DRUG METABOLISM; ENZYME POLYMORPHISM; FEMALE; GENE FREQUENCY; GENOTYPE; HUMAN; HUMAN TISSUE; ISCHEMIC HEART DISEASE; LOADING DRUG DOSE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; STENT THROMBOSIS; THROMBOCYTE AGGREGATION; CORONARY ARTERY DISEASE; CORONARY ARTERY THROMBOSIS; FOLLOW UP; GENETIC POLYMORPHISM; GENETICS; HETEROZYGOTE; METABOLISM; MIDDLE AGED; MULTIVARIATE ANALYSIS; STENT; TREATMENT OUTCOME;

AGED; ARYL HYDROCARBON HYDROXYLASES; CORONARY ARTERY DISEASE; CORONARY THROMBOSIS; FEMALE; FOLLOW-UP STUDIES; GENE FREQUENCY; GENOTYPE; HEMORRHAGE; HETEROZYGOTE; HUMANS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; POLYMORPHISM, GENETIC; RISK FACTORS; STENTS; TICLOPIDINE; TREATMENT OUTCOME;

EID: 76349098199     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.109.885194     Document Type: Article

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