Flexibility of the NSAID binding site in the structure of human cyclooxygenase-2

Nature Structural Biology

Volumn 3, Issue 11, 1996, Pages 927-933

  Luong, Christine ^a   Miller, Aaron ^a   Barnett, Jim ^a   Chow, Joan ^a   Ramesha, Chakk ^a   Browner, Michelle F ^a  

^a ROCHE BIOSCIENCE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ISOENZYME; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN SYNTHASE; PROSTAGLANDIN SYNTHASE INHIBITOR;

ARTICLE; DRUG BINDING SITE; ENZYME ANALYSIS; ENZYME CONFORMATION; ENZYME STRUCTURE; HUMAN; PRIORITY JOURNAL; STRUCTURE ANALYSIS;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BINDING SITES; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; ENZYME INHIBITORS; HUMANS; ISOENZYMES; MEMBRANE PROTEINS; MODELS, MOLECULAR; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY;

EID: 0029911267     PISSN: 10728368     EISSN: None     Source Type: Journal    
DOI: 10.1038/nsb1196-927     Document Type: Article

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