MDR1 genotype-related duodenal absorption rate of digoxin in healthy Japanese subjects

Pharmaceutical Research

Volumn 20, Issue 4, 2003, Pages 552-556

  Morita, Yoshinori ^a   Sakaeda, Toshiyuki ^b   Horinouchi, Masanori ^b   Nakamura, Tsutomu ^b   Kuroda, Kohei ^b   Miki, Ikuya ^a   Yoshimura, Ken ^a   Sakai, Toshiyuki ^a   Shirasaka, Daisuke ^a   Tamura, Takao ^a   Aoyama, Nobuo ^b   Kasuga, Masato ^a   Okumura, Katsuhiko ^b  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KOBE UNIVERSITY   (Japan)

Author keywords

Absorption rate; Digoxin pharmacokinetics; Intraduodenal administration; MDR1; Polymorphism

Indexed keywords

DIGOSIN; DIGOXIN; MULTIDRUG RESISTANCE PROTEIN 1;

ALLELISM; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BLOOD LEVEL; EXON; GENE MUTATION; GENE SEQUENCE; GENETIC POLYMORPHISM; GENOTYPE; HOMOZYGOSITY; HUMAN; INTESTINE ABSORPTION; JAPAN; NORMAL HUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SERUM;

ADMINISTRATION, ORAL; CATHETERS, INDWELLING; DIGOXIN; DUODENUM; ENDOSCOPES, GASTROINTESTINAL; EXONS; GENES, MDR; GENOTYPE; HUMANS; INSTILLATION, DRUG; INTESTINAL ABSORPTION; JAPAN;

EID: 12444273301     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1023282312757     Document Type: Article

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