Influence of treatment duration with a 600-mg dose of clopidogrel before percutaneous coronary revascularization

Journal of the American College of Cardiology

Volumn 44, Issue 11, 2004, Pages 2133-2136

  Kandzari, David E ^a   Berger, Peter B ^a   Kastrati, Adnan ^b   Steinhubl, Steven R ^c   Mehilli, Julinda ^b   Dotzer, Franz ^d   Ten Berg, Jurriën M ^e   Neumann, Franz Josef ^f   Bollwein, Hildegard ^g   Dirschinger, Josef ^g   Schömig, Albert ^b,g  

^a DUKE CLINICAL RESEARCH INSTITUTE   (United States)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c UNIVERSITY OF KENTUCKY   (United States)

^d Germany   (Germany)

^e ST ANTONIUS HOSPITAL   (Netherlands)

^f UNIVERSITY HEART CENTER FREIBURG BAD KROZINGEN   (Germany)

^g TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ABCIXIMAB; CLOPIDOGREL; PLACEBO;

ADULT; AGED; ARTICLE; BLEEDING; CARDIOVASCULAR RISK; CONFIDENCE INTERVAL; CONTROLLED STUDY; DEATH; HEART INFARCTION; HEART MUSCLE REVASCULARIZATION; HUMAN; MAJOR CLINICAL STUDY; MEDICAL EXAMINATION; PRIORITY JOURNAL; RANDOMIZATION; TREATMENT OUTCOME;

AGED; ANGIOPLASTY, TRANSLUMINAL, PERCUTANEOUS CORONARY; ANTIBODIES, MONOCLONAL; CORONARY DISEASE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; PLATELET AGGREGATION INHIBITORS; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; RANDOMIZED CONTROLLED TRIALS; STENTS; TICLOPIDINE; TREATMENT OUTCOME;

EID: 9644291514     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jacc.2004.08.060     Document Type: Article

References (15)

1. A. Schömig, F.-J. Neumann, A. Kastrati A randomized comparison of antiplatelet and anticoagulant therapy after the placement of coronary-artery stents N Engl J Med 334 1996 1084 1089
2. M.B. Leon, D.S. Baim, J.J. Popma A clinical trial comparing three antithrombotic drug regimens after coronary-artery stenting N Engl J Med 339 1998 1665 1671
3. S.R. Mehta, S. Yusuf, R.J.G. Peters., for the CURE Investigators Effects of pretreatment with clopidogrel and aspirin followed by long-term therapy in patients undergoing percutaneous coronary intervention: the PCI-CURE study Lancet 358 2001 526 533
4. S.R. Steinhubl, P.B. Berger, J.T. Mann III., for the CREDO Investigators Early and sustained dual oral antiplatelet therapy following percutaneous coronary intervention: a randomized controlled trial JAMA 288 2002 2411 2420
5. A. Kastrati, J. Mehilli, H. Schühlen., for the Intracoronary Stenting and Antithrombotic Regimen-Rapid Early Action for Coronary Treatment (ISAR-REACT) Study Investigators A clinical trial of abciximab in elective percutaneous coronary intervention after pretreatment with clopidogrel N Engl J Med 350 2004 232 238
6. J.J. Thebault, G. Kieffer, R. Carious Single-dose pharmacodynamics of clopidogrel Semin Thromb Hemost 25 Suppl II 1999 3 8
7. M. Savcic, J. Hauert, F. Bachmann, P.J. Wyld, B. Geudelin, R. Cariou Clopidogrel loading regimens: kinetic profile of pharmacodynamic response in healthy subjects Semin Thromb Hemost 25 Suppl II 1999 15 19
8. G. Helft, J.I. Osende, S.G. Worthley Acute antithrombotic effect of a front-loaded regimen of clopidogrel in patients with atherosclerosis on aspirin Arterioscler Thromb Vasc Biol 20 2000 2316 2321
9. P.A. Gurbel, C.C. Cummings, C.R. Bell, A.B. Alford, C.F. Meister, C.L. Serebruany Onset and extent of platelet inhibition by clopidogrel loading in patients undergoing elective percutaneous coronary stenting: the Plavix Reduction of New Thrombus Recurrence (PRONTO) trial Am Heart J 145 2003 239 247
10. S.R. Steinhubl, S. Darrah, D. Brennan, E. McErlean, P.B. Berger, E.J. Topol Optimal duration of pretreatment with clopidogrel prior to PCI: data from the CREDO trial Circulation 108 Suppl I 2003 I1742
11. M. Gawaz, M. Seyfarth, I. Müller Comparison of effects of clopidogrel versus ticlopidine on platelet function in patients undergoing coronary stent placement Am J Cardiol 87 2001 332 336
12. I. Müller, M. Seyfarth, S. Rüdiger Effect of a high loading dose of clopidogrel on platelet function in patients undergoing coronary stent placement Heart 85 2001 92 93
13. M.E. Bertrand, H.J. Rupprecht, P. Urban, A.H. Gershlick CLASSICS Investigators Double-blind study of the safety of clopidogrel with and without a loading dose in combination with aspirin compared with ticlopidine in combination with aspirin after coronary stenting: the Clopidogrel Aspirin Stent International Cooperative Study (CLASSICS) Circulation 102 2000 624 629
14. M. Taniuchi, H.I. Kurz, J.M. Lasala Randomized comparison of ticlopidine and clopidogrel after intracoronary stent implantation in a broad patient population Circulation 104 2001 539 543
15. M.E. Leimbach, V. Peyrou, U.M. Marzec, N.A.F. Chronos, S.B. King, L.A. Harker Single-dose clopidogrel inhibition of platelet adenosine receptor function in patients with atherosclerotic coronary artery disease Circulation 100 Suppl I 1999 I681