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Volumn 101, Issue 1, 2009, Pages 123-133

Lack of association between aspirin responsiveness and seven candidate gene haplotypes in patients with symptomatic vascular disease

Author keywords

Aspirin; PFA 100; Platelet; SNP; VWF

Indexed keywords

ACETYLSALICYLIC ACID; ADRENALIN; BETA3 INTEGRIN; COLLAGEN; CYCLOOXYGENASE 1; GLYCOPROTEIN IB ALPHA; GLYCOPROTEIN VI; INTEGRIN; INTEGRIN ALPHA2B; PROSTAGLANDIN SYNTHASE; PURINERGIC P2Y1 RECEPTOR; UNCLASSIFIED DRUG; VERY LATE ACTIVATION ANTIGEN 2; VON WILLEBRAND FACTOR; ADENOSINE DIPHOSPHATE; ADHESION RECEPTOR; ALPHA2 INTEGRIN; ANTITHROMBOCYTIC AGENT; DIAGNOSTIC AGENT; FIBRINOGEN RECEPTOR; ITGA2B PROTEIN, HUMAN; ITGB3 PROTEIN, HUMAN; MEMBRANE PROTEIN; PLATELET MEMBRANE GLYCOPROTEIN VI; PTGS1 PROTEIN, HUMAN; PURINERGIC P2 RECEPTOR;

EID: 60849137489     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH08-05-0287     Document Type: Article
Times cited : (45)

References (54)
  • 1
    • 0037065502 scopus 로고    scopus 로고
    • Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients
    • Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients. BMJ 2002; 324:71-86.
    • (2002) BMJ , vol.324 , pp. 71-86
  • 2
    • 0035421783 scopus 로고    scopus 로고
    • Profile and prevalence of aspirin resistance in patients with eardiovascular disease
    • Gum PA, Kottke-Marehant K, Poggio ED, et al. Profile and prevalence of aspirin resistance in patients with eardiovascular disease. Am J Cardiol 2001; 88: 230-235.
    • (2001) Am J Cardiol , vol.88 , pp. 230-235
    • Gum, P.A.1    Kottke-Marehant, K.2    Poggio, E.D.3
  • 3
    • 8344231455 scopus 로고    scopus 로고
    • Aspirin and Clopidogrel. Efficacy, safety, and the issue of drug resistance
    • Cattaneo M. Aspirin and Clopidogrel. Efficacy, safety, and the issue of drug resistance. Arterioseler Thromb Vase Biol 2004; 24: 1980-1987.
    • (2004) Arterioseler Thromb Vase Biol , vol.24 , pp. 1980-1987
    • Cattaneo, M.1
  • 4
    • 1342304430 scopus 로고    scopus 로고
    • Failure of aspirin to prevent atherothrombosis: Potential mechanisms and implications for clinical practice
    • Eikelboom JW, Hankey GJ. Failure of aspirin to prevent atherothrombosis: potential mechanisms and implications for clinical practice. Am J Cardiovasc Drugs 2004; 4: 57-67.
    • (2004) Am J Cardiovasc Drugs , vol.4 , pp. 57-67
    • Eikelboom, J.W.1    Hankey, G.J.2
  • 5
    • 0037454168 scopus 로고    scopus 로고
    • A prospective, blinded determination of the natural his- tory of aspirin resistance among stable patients with cardiovascular disease
    • Gum PA, Kottke-Marchant K, Welsh PA, et al. A prospective, blinded determination of the natural his- tory of aspirin resistance among stable patients with cardiovascular disease. J Am Coll Cardiol 2003; 41: 961-965.
    • (2003) J Am Coll Cardiol , vol.41 , pp. 961-965
    • Gum, P.A.1    Kottke-Marchant, K.2    Welsh, P.A.3
  • 6
    • 0037454169 scopus 로고    scopus 로고
    • Aspirin resistance: A new independent predictor of vascular events?
    • Eikelboom JW, Hankey GJ. Aspirin resistance: a new independent predictor of vascular events? J Am Coll Cardiol 2003; 41: 966-968.
    • (2003) J Am Coll Cardiol , vol.41 , pp. 966-968
    • Eikelboom, J.W.1    Hankey, G.J.2
  • 8
    • 42949165089 scopus 로고    scopus 로고
    • The role of aspirin in cardiovascular prevention: Implications of aspirin resistance
    • Gasparyan AY, Watson T, Lip GY. The role of aspirin in cardiovascular prevention: implications of aspirin resistance. J Am Coll Cardiol 2008; 51: 1829-1843.
    • (2008) J Am Coll Cardiol , vol.51 , pp. 1829-1843
    • Gasparyan, A.Y.1    Watson, T.2    Lip, G.Y.3
  • 10
    • 39749155679 scopus 로고    scopus 로고
    • Lack of reproducibility of assessment of aspirin responsiveness by optical aggregometry and two platelet function tests
    • Harrison P, Segal H, Silver L, et al. Lack of reproducibility of assessment of aspirin responsiveness by optical aggregometry and two platelet function tests. Platelets 2008; 19: 119-124.
    • (2008) Platelets , vol.19 , pp. 119-124
    • Harrison, P.1    Segal, H.2    Silver, L.3
  • 11
    • 0033960903 scopus 로고    scopus 로고
    • Monitoring of aspirin (ASA) pharmacodynamics with the platelet function analyzer PFA-100
    • Homoncik M, Jilma B, HergovichN, et al. Monitoring of aspirin (ASA) pharmacodynamics with the platelet function analyzer PFA-100. Thromb Haemost 2000;83:316-321.
    • (2000) Thromb Haemost , vol.83 , pp. 316-321
    • Homoncik, M.1    Jilma, B.2    HergovichN3
  • 12
    • 2942519743 scopus 로고    scopus 로고
    • Change in stroke incidence, mortality, case-fatality, severity, and risk factors in Oxfordshire, UK from 1981 to 2004 (Oxford Vascular Study)
    • Rothwell PM, Coull AJ, Giles MF, et al. Change in stroke incidence, mortality, case-fatality, severity, and risk factors in Oxfordshire, UK from 1981 to 2004 (Oxford Vascular Study). Lancet 2004; 363: 1925-1933.
    • (2004) Lancet , vol.363 , pp. 1925-1933
    • Rothwell, P.M.1    Coull, A.J.2    Giles, M.F.3
  • 13
    • 27844562639 scopus 로고    scopus 로고
    • Population-based study of event-rate, incidence, case fatality, and mortality for all acute vascular events in all arterial territories (Oxford Vascular Study)
    • Rothwell PM, Coull AJ, Silver LE, et al. Population-based study of event-rate, incidence, case fatality, and mortality for all acute vascular events in all arterial territories (Oxford Vascular Study). Lancet 2005; 366: 1773-1783.
    • (2005) Lancet , vol.366 , pp. 1773-1783
    • Rothwell, P.M.1    Coull, A.J.2    Silver, L.E.3
  • 14
    • 4344650039 scopus 로고    scopus 로고
    • Direct assessment of completeness of ascertainment in a stroke incidence study
    • Coull AJ, Silver LE, Bull LM, et al. Direct assessment of completeness of ascertainment in a stroke incidence study. Stroke 2004; 35: 2041-2045.
    • (2004) Stroke , vol.35 , pp. 2041-2045
    • Coull, A.J.1    Silver, L.E.2    Bull, L.M.3
  • 15
    • 18244392669 scopus 로고    scopus 로고
    • Screening for aspirin responsiveness after transient ischemic attack and stroke: Comparison of 2 point-of-care platelet function tests with optical aggregometry
    • Harrison P, Segal H, Blasbery K, et al. Screening for aspirin responsiveness after transient ischemic attack and stroke: comparison of 2 point-of-care platelet function tests with optical aggregometry. Stroke 2005; 36: 1001-1005.
    • (2005) Stroke , vol.36 , pp. 1001-1005
    • Harrison, P.1    Segal, H.2    Blasbery, K.3
  • 16
    • 0032919477 scopus 로고    scopus 로고
    • Performance of the platelet function analyser PFA-100 in testing abnormalities of primary haemostasis
    • Harrison P, Robinson MS, Mackie IJ, et al. Performance of the platelet function analyser PFA-100 in testing abnormalities of primary haemostasis. Blood Coagul Fibrinolysis 1999; 10: 25-31.
    • (1999) Blood Coagul Fibrinolysis , vol.10 , pp. 25-31
    • Harrison, P.1    Robinson, M.S.2    Mackie, I.J.3
  • 17
    • 0034867946 scopus 로고    scopus 로고
    • Platelet function analyzer (PFA-100): A tool to quantify congenital or acquired platelet dysfunction
    • Jilma B. Platelet function analyzer (PFA-100): a tool to quantify congenital or acquired platelet dysfunction. J Lab Clin Med 2001; 138: 152-163.
    • (2001) J Lab Clin Med , vol.138 , pp. 152-163
    • Jilma, B.1
  • 18
    • 38349126676 scopus 로고    scopus 로고
    • Response variability to aspirin as assessed by the platelet function analyzer (PFA)-100. A systematic review
    • Crescente M, Di CA, Lacoviello L, et al. Response variability to aspirin as assessed by the platelet function analyzer (PFA)-100. A systematic review. Thromb Haemost 2008;99: 14-26.
    • (2008) Thromb Haemost , vol.99 , pp. 14-26
    • Crescente, M.1    Di, C.A.2    Lacoviello, L.3
  • 19
    • 0035869295 scopus 로고    scopus 로고
    • Allele-dependent transcriptional regulation of the human integrin alpha 2 gene
    • Jacquelin B, Tarantino MD, Kritzik M, et al. Allele-dependent transcriptional regulation of the human integrin alpha 2 gene. Blood 2001; 97: 1721-1726.
    • (2001) Blood , vol.97 , pp. 1721-1726
    • Jacquelin, B.1    Tarantino, M.D.2    Kritzik, M.3
  • 20
    • 0032173427 scopus 로고    scopus 로고
    • Kritzik M. Savage B, Nugent DJ, et al. Nucleotide polymorphisms in the alpha 2 gene define multiple alleles which are associated with differences in platelet alpha 2 beta 1. Blood 1998; 92: 2382-2388.
    • Kritzik M. Savage B, Nugent DJ, et al. Nucleotide polymorphisms in the alpha 2 gene define multiple alleles which are associated with differences in platelet alpha 2 beta 1. Blood 1998; 92: 2382-2388.
  • 21
    • 0028173806 scopus 로고
    • Localization of the Br polymorphism on a 144 bp Exon of the GPIa gene and its application in platelet DNA typing
    • Kalb R, Santoso S, UnkelbachK. et al. Localization of the Br polymorphism on a 144 bp Exon of the GPIa gene and its application in platelet DNA typing. Thromb Haemost 1994; 71: 651-654.
    • (1994) Thromb Haemost , vol.71 , pp. 651-654
    • Kalb, R.1    Santoso, S.2    UnkelbachK3
  • 22
    • 25144435979 scopus 로고    scopus 로고
    • Platelet glycoprotein Ibalpha and integrin alphabeta polymorphisms: Gene frequencies and linkage disequilibrium in a population diversity panel
    • Di Paola J, Jugessur A, Goldman T, et al. Platelet glycoprotein Ibalpha and integrin alphabeta polymorphisms: gene frequencies and linkage disequilibrium in a population diversity panel. J Thromb Haemost 2005; 3: 1511-1521.
    • (2005) J Thromb Haemost , vol.3 , pp. 1511-1521
    • Di Paola, J.1    Jugessur, A.2    Goldman, T.3
  • 23
    • 0033937685 scopus 로고    scopus 로고
    • Genetic variants of platelet glycoprotein receptors and risk of stroke in young women
    • Reiner AP. Kumar FN, Schwartz SM, et al. Genetic variants of platelet glycoprotein receptors and risk of stroke in young women. Stroke 2000; 31: 1628-1633.
    • (2000) Stroke , vol.31 , pp. 1628-1633
    • Reiner, A.P.1    Kumar, F.N.2    Schwartz, S.M.3
  • 24
    • 0024588794 scopus 로고    scopus 로고
    • Newman PJ, Derbes RS, Aster RH. The human platelet alloantigens, PLA1 and PLA2, are associated with a leucine33/proline33 amino acid polymorphism in membrane glycoprotein IIIa, and are distinguishable by DNA typing. J Clin Invest 1989; 83: 1778-1781.
    • Newman PJ, Derbes RS, Aster RH. The human platelet alloantigens, PLA1 and PLA2, are associated with a leucine33/proline33 amino acid polymorphism in membrane glycoprotein IIIa, and are distinguishable by DNA typing. J Clin Invest 1989; 83: 1778-1781.
  • 25
    • 0033168684 scopus 로고    scopus 로고
    • Kozak sequence polymorphism of the glycoprotein (GP) Ibalpha gene is a major determinant of the plasma membrane levels of the platelet GP Ib- IX-V complex
    • Afshar-Kharghan V, Li CQ, Khoshnevis-Asl M. et al. Kozak sequence polymorphism of the glycoprotein (GP) Ibalpha gene is a major determinant of the plasma membrane levels of the platelet GP Ib- IX-V complex. Blood 1999; 94: 186-191.
    • (1999) Blood , vol.94 , pp. 186-191
    • Afshar-Kharghan, V.1    Li, C.Q.2    Khoshnevis-Asl, M.3
  • 26
    • 0029897135 scopus 로고    scopus 로고
    • Systematic screening for genetic polymorphism in human platelet glycoprotein Ib alpha
    • Kaski S, Kekomaki R, Partanen J. Systematic screening for genetic polymorphism in human platelet glycoprotein Ib alpha. Immunogenetics 1996; 44: 170-176.
    • (1996) Immunogenetics , vol.44 , pp. 170-176
    • Kaski, S.1    Kekomaki, R.2    Partanen, J.3
  • 27
    • 0026610362 scopus 로고
    • 145 amino acid polymorphism, which is associated with the HBA-2 (Ko) alloantigens
    • 145 amino acid polymorphism, which is associated with the HBA-2 (Ko) alloantigens. J Clin Invest 1992; 89: 381-384.
    • (1992) J Clin Invest , vol.89 , pp. 381-384
    • Kuijpers, R.W.A.M.1    Faber, N.M.2    Cuypers, H.T.M.3
  • 28
    • 0026720406 scopus 로고
    • Genetic and structural characterization of an amino acid dimorphism in glycoprotein Iba involved in platelet transfusion refractoriness
    • Murata M, Furihata K, Ishida F, et al. Genetic and structural characterization of an amino acid dimorphism in glycoprotein Iba involved in platelet transfusion refractoriness. Blood 1992; 79: 3086-3090.
    • (1992) Blood , vol.79 , pp. 3086-3090
    • Murata, M.1    Furihata, K.2    Ishida, F.3
  • 29
    • 4944264978 scopus 로고    scopus 로고
    • An association of candidate gene haplotypes and bleeding severity in Von Willebrand Disease (VWD) type 1 pedigrees
    • Kunicki TJ, Federici AB, Salomon DR, et al. An association of candidate gene haplotypes and bleeding severity in Von Willebrand Disease (VWD) type 1 pedigrees. Blood 2004; 104: 2359-2367.
    • (2004) Blood , vol.104 , pp. 2359-2367
    • Kunicki, T.J.1    Federici, A.B.2    Salomon, D.R.3
  • 30
    • 0038819123 scopus 로고    scopus 로고
    • The low-frequency allele of the platelet collagen signaling receptor glycoprotein VI is associated with reduced functional responses and expression
    • Joutsi-Korhonen L, Smethurst PA, Rankin A, et al. The low-frequency allele of the platelet collagen signaling receptor glycoprotein VI is associated with reduced functional responses and expression. Blood 2003; 101:4372-4379.
    • (2003) Blood , vol.101 , pp. 4372-4379
    • Joutsi-Korhonen, L.1    Smethurst, P.A.2    Rankin, A.3
  • 32
    • 28444484957 scopus 로고    scopus 로고
    • Cyclooxygenase-1 haplotype modulates platelet response to aspirin
    • Maree AO, Curtin RJ, Chubb A, et al. Cyclooxygenase-1 haplotype modulates platelet response to aspirin. J Thromb Haemost 2005; 3: 2340-2345.
    • (2005) J Thromb Haemost , vol.3 , pp. 2340-2345
    • Maree, A.O.1    Curtin, R.J.2    Chubb, A.3
  • 33
    • 0346433909 scopus 로고    scopus 로고
    • In vitro aspirin resistance detected by PFA-100 closure time: Pivotal role of plasma von Willebrand factor
    • Chakroun T, Gerotziafas G, Robert F, et al. In vitro aspirin resistance detected by PFA-100 closure time: pivotal role of plasma von Willebrand factor. Br J Haematol 2004; 124: 80-85.
    • (2004) Br J Haematol , vol.124 , pp. 80-85
    • Chakroun, T.1    Gerotziafas, G.2    Robert, F.3
  • 34
    • 39549117350 scopus 로고    scopus 로고
    • Use of the PFA-100 closure time to predict cardiovascular events in aspirin-treated cardiovascular patients: A systematic review and meta-analysis
    • Reny JL, de MP, Dauzat M, et al. Use of the PFA-100 closure time to predict cardiovascular events in aspirin-treated cardiovascular patients: a systematic review and meta-analysis. J Thromb Haemost 2008; 6: 444-450.
    • (2008) J Thromb Haemost , vol.6 , pp. 444-450
    • Reny1    JL, D.M.2    Dauzat, M.3
  • 35
    • 38949119325 scopus 로고    scopus 로고
    • Aspirin "resistance" and risk of cardiovascular morbidity: Systematic review and meta-analysis
    • Krasopoulos G, Blister SJ, Beattie WS, et al. Aspirin "resistance" and risk of cardiovascular morbidity: systematic review and meta-analysis. BMJ 2008; 336: 195-198.
    • (2008) BMJ , vol.336 , pp. 195-198
    • Krasopoulos, G.1    Blister, S.J.2    Beattie, W.S.3
  • 36
    • 34447503098 scopus 로고    scopus 로고
    • Association of laboratory-defined aspirin resistance with a higher risk of recurrent cardiovascular events: A systematic review and meta-analysis
    • Snoep JD, Hovens MM, Eikenboom JC, et al. Association of laboratory-defined aspirin resistance with a higher risk of recurrent cardiovascular events: a systematic review and meta-analysis. Arch Intern Med 2007; 167: 1593-1599.
    • (2007) Arch Intern Med , vol.167 , pp. 1593-1599
    • Snoep, J.D.1    Hovens, M.M.2    Eikenboom, J.C.3
  • 37
    • 44949172436 scopus 로고    scopus 로고
    • PFA-100 closure time to predict cardiovascular events in aspirintreated cardiovascular patients: A meta-analysis of 19 studies comprising 3,003 patients
    • Crescente M, Di CA, Lacoviello L, et al. PFA-100 closure time to predict cardiovascular events in aspirintreated cardiovascular patients: A meta-analysis of 19 studies comprising 3,003 patients. Thromb Haemost 2008; 99: 1129-1131.
    • (2008) Thromb Haemost , vol.99 , pp. 1129-1131
    • Crescente, M.1    Di, C.A.2    Lacoviello, L.3
  • 38
    • 33344478392 scopus 로고    scopus 로고
    • Seven haemostatic gene polymorphisms in coronary disease: Meta-analysis of 66,155 cases and 91,307 controls
    • Ye Z, Liu EH, Higgins JP, et al. Seven haemostatic gene polymorphisms in coronary disease: meta-analysis of 66,155 cases and 91,307 controls. Lancet 2006; 367:651-658.
    • (2006) Lancet , vol.367 , pp. 651-658
    • Ye, Z.1    Liu, E.H.2    Higgins, J.P.3
  • 39
    • 0038267247 scopus 로고    scopus 로고
    • The influence of platelet glycoprotein polymorphisms on receptor function and risk for thrombosis
    • Kunicki TJ, Nugent DJ. The influence of platelet glycoprotein polymorphisms on receptor function and risk for thrombosis. Vox Sang 2002; 83: 85-90.
    • (2002) Vox Sang , vol.83 , pp. 85-90
    • Kunicki, T.J.1    Nugent, D.J.2
  • 40
    • 0034073762 scopus 로고    scopus 로고
    • The P1(A2) polymorphism of integrin beta(3) enhances outdie-in signaling and adhesive functions
    • VijayanKV, Goldschmidt-Clermont PJ, Roos C, et al. The P1(A2) polymorphism of integrin beta(3) enhances outdie-in signaling and adhesive functions, J Clin Invest 2000; 105:793-802.
    • (2000) J Clin Invest , vol.105 , pp. 793-802
    • VijayanKV1    Goldschmidt-Clermont, P.J.2    Roos, C.3
  • 41
    • 18244414272 scopus 로고    scopus 로고
    • Platelet GP IIIa PI(A) polymorphisms display different sensitivities to agonists
    • Michelson AD, Furman MI, Goldschmidt-Clermont P, et al. Platelet GP IIIa PI(A) polymorphisms display different sensitivities to agonists. Circulation 2000; 101: 1013-1018.
    • (2000) Circulation , vol.101 , pp. 1013-1018
    • Michelson, A.D.1    Furman, M.I.2    Goldschmidt-Clermont, P.3
  • 42
    • 0033761053 scopus 로고    scopus 로고
    • Relationship between bleeding time, aspirin and the P1A1/A2 polymorphism of platelet glycoprotein IIIa
    • Szczeklik A, Lindas A, Sanak M, et al. Relationship between bleeding time, aspirin and the P1A1/A2 polymorphism of platelet glycoprotein IIIa, Br J Haematol 2000; 110:965-967.
    • (2000) Br J Haematol , vol.110 , pp. 965-967
    • Szczeklik, A.1    Lindas, A.2    Sanak, M.3
  • 43
    • 0035852892 scopus 로고    scopus 로고
    • Platelet glycoprotein IIIa pl(a) polymorphism and effects of aspirin on thrombin generation
    • Szezeklik A, Sanak M, Undas A. Platelet glycoprotein IIIa pl(a) polymorphism and effects of aspirin on thrombin generation. Circulation 2001; 103: E33-E34.
    • (2001) Circulation , vol.103
    • Szezeklik, A.1    Sanak, M.2    Undas, A.3
  • 44
    • 0042735242 scopus 로고    scopus 로고
    • Resistance in vitro to low-dose aspirin is associated with platelet P1A1 (GP IIIa) polymorphism but not with C807T(GP Ia/IIa) and C-5T Kozak (GP Ibalpha) polymorphisms
    • Macchi L, Christiaens L, Brabant S, et al. Resistance in vitro to low-dose aspirin is associated with platelet P1A1 (GP IIIa) polymorphism but not with C807T(GP Ia/IIa) and C-5T Kozak (GP Ibalpha) polymorphisms. J Am Coll Cardiol 2003; 42: 1115-1119.
    • (2003) J Am Coll Cardiol , vol.42 , pp. 1115-1119
    • Macchi, L.1    Christiaens, L.2    Brabant, S.3
  • 45
    • 31644438586 scopus 로고    scopus 로고
    • Effect of platelet antigen polymorphism on platelet inhibition by aspirin, clopidogrel, or their combination
    • Cooke GE, Liu-StrattonY, Ferketich AK, et al. Effect of platelet antigen polymorphism on platelet inhibition by aspirin, clopidogrel, or their combination. J Am Coll Cardiol 2006; 47: 541-546.
    • (2006) J Am Coll Cardiol , vol.47 , pp. 541-546
    • Cooke, G.E.1    StrattonY, L.2    Ferketich, A.K.3
  • 46
    • 0032565146 scopus 로고    scopus 로고
    • PIA2 polymorphism and efficacy of aspirin
    • Cooke GE, Bray PF, Hamlington JD, et al. PIA2 polymorphism and efficacy of aspirin. Lancet 1998; 351: 1253-1253.
    • (1998) Lancet , vol.351 , pp. 1253-1253
    • Cooke, G.E.1    Bray, P.F.2    Hamlington, J.D.3
  • 47
    • 33845490833 scopus 로고    scopus 로고
    • Genetic polymorphisms of the platelet receptors P2Y(12), P2Y(1) and GP IIIa and response to aspirin and elopidogrel
    • Lev EI, Patel RT, Gufhikonda S, et al. Genetic polymorphisms of the platelet receptors P2Y(12), P2Y(1) and GP IIIa and response to aspirin and elopidogrel. Thromb Res 2007; 119: 355-360.
    • (2007) Thromb Res , vol.119 , pp. 355-360
    • Lev, E.I.1    Patel, R.T.2    Gufhikonda, S.3
  • 48
    • 33751531567 scopus 로고    scopus 로고
    • Lack of association between gene sequence variations of platelet membrane receptors and aspirin responsiveness detected by the PFA-100 system in patients with coronary artery disease
    • Bernardo E, Angiolillo DJ, Ramirez C, et al. Lack of association between gene sequence variations of platelet membrane receptors and aspirin responsiveness detected by the PFA-100 system in patients with coronary artery disease. Platelets 2006; 17: 586-590.
    • (2006) Platelets , vol.17 , pp. 586-590
    • Bernardo, E.1    Angiolillo, D.J.2    Ramirez, C.3
  • 50
    • 12844269195 scopus 로고    scopus 로고
    • Biological assessment of aspirin efficacy on healthy individuals: Heterogeneous response or aspirin failure?
    • Gonzalez-Conejero R, Rivera J, Corral J, et al. Biological assessment of aspirin efficacy on healthy individuals: heterogeneous response or aspirin failure? Stroke 2005; 36: 276-280.
    • (2005) Stroke , vol.36 , pp. 276-280
    • Gonzalez-Conejero, R.1    Rivera, J.2    Corral, J.3
  • 51
    • 33645546989 scopus 로고    scopus 로고
    • Polymorphisms of COX-1 and GPVI associate with the antiplatelet effect of aspirin in coronary artery disease patients
    • Lepantalo A, Mikkelsson J, Resendiz JC, et al. Polymorphisms of COX-1 and GPVI associate with the antiplatelet effect of aspirin in coronary artery disease patients. Thromb Haemost 2006; 95: 253-259.
    • (2006) Thromb Haemost , vol.95 , pp. 253-259
    • Lepantalo, A.1    Mikkelsson, J.2    Resendiz, J.C.3
  • 52
    • 38649098154 scopus 로고    scopus 로고
    • Platelet responsiveness to in vitro aspirin is independent of COX-1 and COX-2 protein levels and polymorphisms
    • Takahashi S, Ushida M, Komine R, et al. Platelet responsiveness to in vitro aspirin is independent of COX-1 and COX-2 protein levels and polymorphisms. Thromb Res 2008; 121: 509-517.
    • (2008) Thromb Res , vol.121 , pp. 509-517
    • Takahashi, S.1    Ushida, M.2    Komine, R.3
  • 53
    • 0037101578 scopus 로고    scopus 로고
    • Resistance to aspirin in vitro is associated with increased platelet sensitivity to adenosine diphosphate
    • Macchi L, Christiaens L, Brabant S, et al. Resistance to aspirin in vitro is associated with increased platelet sensitivity to adenosine diphosphate. Thromb Res 2002; 107: 45-49.
    • (2002) Thromb Res , vol.107 , pp. 45-49
    • Macchi, L.1    Christiaens, L.2    Brabant, S.3
  • 54
    • 47249143688 scopus 로고    scopus 로고
    • Pharmacogenetics of aspirin resistance: A comprehensive systematic review
    • Goodman T, Ferro A, Sharma E Pharmacogenetics of aspirin resistance: a comprehensive systematic review. Br J Clin Pharmacol 2008; 66: 222-232.
    • (2008) Br J Clin Pharmacol , vol.66 , pp. 222-232
    • Goodman, T.1    Ferro, A.2    Sharma, E.3


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