Effects of selective cyclooxygenase-2 inhibition on vascular responses and thrombosis in canine coronary arteries

Circulation

Volumn 104, Issue 7, 2001, Pages 820-825

  Hennan, James K ^a   Huang, Jinbao ^a   Barrett, Terrance D ^a   Driscoll, Edward M ^a   Willens, David E ^a   Park, Andrew M ^a   Crofford, Leslie J ^a   Lucchesi, Benedict R ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Aspirin; Cyclooxygenase; Prostaglandins; Thrombosis

Indexed keywords

ACETYLCHOLINE; ACETYLSALICYLIC ACID; ARACHIDONIC ACID; CELECOXIB; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY DILATATION; CORONARY ARTERY THROMBOSIS; DOG; DRUG SAFETY; ENZYME INHIBITION; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS INHIBITION; VASOMOTOR REFLEX;

EID: 0035859802     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/hc3301.092790     Document Type: Article

References (25)

1. Eicosanoids and the gastrointestinal tract
2. Cloning two isoforms of rat cyclooxygenase: Differential regulation of their expression
3. The utility of excitatory amino acid (EAA) antagonists as analgesic agents, I: Comparison of the antinociceptive activity of various classes of EAA antagonists in mechanical, thermal and chemical nociceptive tests
4. Nonsteroidal anti-inflammatory drugs and peptic ulcer disease
5. NS-398, a novel non-steroidal anti-inflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions
6. The eicosanoids and their biochemical mechanisms of action
7. Selective regulation of cellular cyclooxygenase by dexamethasone and endotoxin in mice
8. Cytokine mediated induction of COX-2 by activation of tyrosine kinase in bovine endothelial cells stimulated with bacterial LPS
9. Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: The human pharmacology of a selective inhibitor of COX-2
10. Thrombosis in patients with connective tissue diseases treated with specific cyclooxygenase 2 inhibitors: A report of four cases
11. Selective cyclooxygenase-2 inhibition with celecoxib elevates blood pressure and promotes leukocyte adherence
12. Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction
13. Localization of cyclooxygenase-1 and -2 in adult and fetal human kidney: Implication for renal function
14. Electrical induction of coronary artery thrombosis in the ambulatory canine: A model for in vivo evaluation of anti-thrombotic agents
15. High dose intravenous aspirin, not low dose intravenous or oral aspirin, inhibits thrombus formation and stabilizes blood flow in experimental coronary vascular injury
16. Isolation and characterization of the complementary DNA for sheep seminal vesicle prostaglandin endoperoxidase synthase (cyclooxygenase)
17. Primary structure of prostaglandin G/H synthase from sheep vesicular gland determined from the complementary DNA sequence
18. Selective inhibition of inducible cyclooxygenase 2 in vivo is anti-inflammatory and nonulcerogenic
19. The endothelial cells as a metabolic and endocrine organ
20. The protective dose of the potent GPIIb/IIIa antagonist SC-54701A is reduced when used in combination with aspirin and heparin in a canine model of coronary artery thrombosis
21. Augmented expression of cyclooxygenase-2 in human atherosclerotic lesions
22. Altered pain perception and inflammatory response in mice lacking prostacyclin receptor
23. Evidence for a bi-directional prostaglandin endoperoxide shunt between platelets and the bovine coronary artery
24. 2 in mixed incubations of endothelial cells and aspirin-treated platelets strongly depends on the prostaglandin I-synthase activity
25. Selective inhibitors of cyclooxygenase-2: A growing class of anti-inflammatory drugs