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Volumn 42, Issue , 2014, Pages 145-161

Role of crystallins in ocular neuroprotection and axonal regeneration

Author keywords

Axonal regrowth; Crystallins; Glaucoma injury; Neuroprotection; Retina

Indexed keywords

BETA B2 CRYSTALLIN; BETA CRYSTALLIN; CILIARY NEUROTROPHIC FACTOR; CRYSTALLIN; GAMMA CRYSTALLIN; UNCLASSIFIED DRUG;

EID: 84906064796     PISSN: 13509462     EISSN: 18731635     Source Type: Journal    
DOI: 10.1016/j.preteyeres.2014.06.004     Document Type: Review
Times cited : (65)

References (167)
  • 1
    • 79959362400 scopus 로고    scopus 로고
    • AlphaB-crystallin, a small heat shock protein, modulates NF-kappaB activity in a phosphorylation-dependent manner and protects muscle myoblasts from TNF-alpha induced cytotoxicity
    • Adhikari A.S., Singh B.N., Rao K.S., Rao Ch M. alphaB-crystallin, a small heat shock protein, modulates NF-kappaB activity in a phosphorylation-dependent manner and protects muscle myoblasts from TNF-alpha induced cytotoxicity. Biochim. Biophys. Acta 2011, 1813:1532-1542.
    • (2011) Biochim. Biophys. Acta , vol.1813 , pp. 1532-1542
    • Adhikari, A.S.1    Singh, B.N.2    Rao, K.S.3    Rao Ch, M.4
  • 3
    • 33845425645 scopus 로고    scopus 로고
    • Crystallins in the eye: function and pathology
    • Andley U.P. Crystallins in the eye: function and pathology. Prog. Retin. Eye Res. 2007, 26:78-98.
    • (2007) Prog. Retin. Eye Res. , vol.26 , pp. 78-98
    • Andley, U.P.1
  • 4
    • 0037155819 scopus 로고    scopus 로고
    • The R116C mutation in alpha A-crystallin diminishes its protective ability against stress-induced lens epithelial cell apoptosis
    • Andley U.P., Patel H.C., Xi J.H. The R116C mutation in alpha A-crystallin diminishes its protective ability against stress-induced lens epithelial cell apoptosis. J. Biol. Chem. 2002, 277:10178-10186.
    • (2002) J. Biol. Chem. , vol.277 , pp. 10178-10186
    • Andley, U.P.1    Patel, H.C.2    Xi, J.H.3
  • 5
    • 0034711260 scopus 로고    scopus 로고
    • Differential protective activity of alpha A- and alphaB-crystallin in lens epithelial cells
    • Andley U.P., Song Z., Wawrousek E.F., Fleming T.P., Bassnett S. Differential protective activity of alpha A- and alphaB-crystallin in lens epithelial cells. J. Biol. Chem. 2000, 275:36823-36831.
    • (2000) J. Biol. Chem. , vol.275 , pp. 36823-36831
    • Andley, U.P.1    Song, Z.2    Wawrousek, E.F.3    Fleming, T.P.4    Bassnett, S.5
  • 6
    • 3142543752 scopus 로고    scopus 로고
    • Phosphorylation of alphaB-crystallin alters chaperone function through loss of dimeric substructure
    • Aquilina J.A., Benesch J.L., Ding L.L., Yaron O., Horwitz J., Robinson C.V. Phosphorylation of alphaB-crystallin alters chaperone function through loss of dimeric substructure. J. Biol. Chem. 2004, 279:28675-28680.
    • (2004) J. Biol. Chem. , vol.279 , pp. 28675-28680
    • Aquilina, J.A.1    Benesch, J.L.2    Ding, L.L.3    Yaron, O.4    Horwitz, J.5    Robinson, C.V.6
  • 7
    • 78651266454 scopus 로고    scopus 로고
    • Expression and functions of heat shock proteins in the normal and pathological mammalian eye
    • Arrigo A.P., Simon S. Expression and functions of heat shock proteins in the normal and pathological mammalian eye. Curr. Mol. Med. 2010, 10:776-793.
    • (2010) Curr. Mol. Med. , vol.10 , pp. 776-793
    • Arrigo, A.P.1    Simon, S.2
  • 9
    • 34547758344 scopus 로고    scopus 로고
    • Combinatorial treatments for promoting axon regeneration in the CNS: strategies for overcoming inhibitory signals and activating neurons' intrinsic growth state
    • Benowitz L.I., Yin Y. Combinatorial treatments for promoting axon regeneration in the CNS: strategies for overcoming inhibitory signals and activating neurons' intrinsic growth state. Dev. Neurobiol. 2007, 67:1148-1165.
    • (2007) Dev. Neurobiol. , vol.67 , pp. 1148-1165
    • Benowitz, L.I.1    Yin, Y.2
  • 10
    • 33751178359 scopus 로고    scopus 로고
    • Enhanced survival and regeneration of axotomized retinal neurons by repeated delivery of cell-permeable C3-like Rho antagonists
    • Bertrand J., Di Polo A., McKerracher L. Enhanced survival and regeneration of axotomized retinal neurons by repeated delivery of cell-permeable C3-like Rho antagonists. Neurobiol. Dis. 2007, 25:65-72.
    • (2007) Neurobiol. Dis. , vol.25 , pp. 65-72
    • Bertrand, J.1    Di Polo, A.2    McKerracher, L.3
  • 11
    • 13944274451 scopus 로고    scopus 로고
    • Application of Rho antagonist to neuronal cell bodies promotes neurite growth in compartmented cultures and regeneration of retinal ganglion cell axons in the optic nerve of adult rats
    • Bertrand J., Winton M.J., Rodriguez-Hernandez N., Campenot R.B., McKerracher L. Application of Rho antagonist to neuronal cell bodies promotes neurite growth in compartmented cultures and regeneration of retinal ganglion cell axons in the optic nerve of adult rats. J. Neurosci. 2005, 25:1113-1121.
    • (2005) J. Neurosci. , vol.25 , pp. 1113-1121
    • Bertrand, J.1    Winton, M.J.2    Rodriguez-Hernandez, N.3    Campenot, R.B.4    McKerracher, L.5
  • 12
    • 84887576517 scopus 로고    scopus 로고
    • Secretion of alphaB-Crystallin via exosomes: new clues to the function of human retinal pigment epithelium
    • Bhat S.P., Gangalum R.K. Secretion of alphaB-Crystallin via exosomes: new clues to the function of human retinal pigment epithelium. Commun. Integr. Biol. 2011, 4:739-741.
    • (2011) Commun. Integr. Biol. , vol.4 , pp. 739-741
    • Bhat, S.P.1    Gangalum, R.K.2
  • 13
    • 0024578954 scopus 로고
    • Alpha B subunit of lens-specific protein alpha-crystallin is present in other ocular and non-ocular tissues
    • Bhat S.P., Nagineni C.N. alpha B subunit of lens-specific protein alpha-crystallin is present in other ocular and non-ocular tissues. Biochem. Biophys. Res. Commun. 1989, 158:319-325.
    • (1989) Biochem. Biophys. Res. Commun. , vol.158 , pp. 319-325
    • Bhat, S.P.1    Nagineni, C.N.2
  • 14
    • 18644381267 scopus 로고    scopus 로고
    • Pax-6 expression in posthatch chick retina during and recovery from form-deprivation myopia
    • Bhat S.P., Rayner S.A., Chau S.C., Ariyasu R.G. Pax-6 expression in posthatch chick retina during and recovery from form-deprivation myopia. Dev. Neurosci. 2004, 26:328-335.
    • (2004) Dev. Neurosci. , vol.26 , pp. 328-335
    • Bhat, S.P.1    Rayner, S.A.2    Chau, S.C.3    Ariyasu, R.G.4
  • 17
    • 84873398282 scopus 로고    scopus 로고
    • Crystallin-beta-b2-overexpressing NPCs support the survival of injured retinal ganglion cells and photoreceptors in rats
    • Böhm M.R., Pfrommer S., Chiwitt C., Bruckner M., Melkonyan H., Thanos S. Crystallin-beta-b2-overexpressing NPCs support the survival of injured retinal ganglion cells and photoreceptors in rats. Invest. Ophthalmol. Vis. Sci. 2012, 53:8265-8279.
    • (2012) Invest. Ophthalmol. Vis. Sci. , vol.53 , pp. 8265-8279
    • Böhm, M.R.1    Pfrommer, S.2    Chiwitt, C.3    Bruckner, M.4    Melkonyan, H.5    Thanos, S.6
  • 18
    • 0031017669 scopus 로고    scopus 로고
    • Targeted disruption of the mouse alpha A-crystallin gene induces cataract and cytoplasmic inclusion bodies containing the small heat shock protein alpha B-crystallin
    • Brady J.P., Garland D., Duglas-Tabor Y., Robison W.G., Groome A., Wawrousek E.F. Targeted disruption of the mouse alpha A-crystallin gene induces cataract and cytoplasmic inclusion bodies containing the small heat shock protein alpha B-crystallin. Proc. Natl. Acad. Sci. U. S. A. 1997, 94:884-889.
    • (1997) Proc. Natl. Acad. Sci. U. S. A. , vol.94 , pp. 884-889
    • Brady, J.P.1    Garland, D.2    Duglas-Tabor, Y.3    Robison, W.G.4    Groome, A.5    Wawrousek, E.F.6
  • 20
    • 42649094476 scopus 로고    scopus 로고
    • The optic vesicle promotes cornea to lens transdifferentiation in larval Xenopus laevis
    • Cannata S.M., Bernardini S., Filoni S., Gargioli C. The optic vesicle promotes cornea to lens transdifferentiation in larval Xenopus laevis. J. Anat. 2008, 212:621-626.
    • (2008) J. Anat. , vol.212 , pp. 621-626
    • Cannata, S.M.1    Bernardini, S.2    Filoni, S.3    Gargioli, C.4
  • 21
    • 49049120741 scopus 로고    scopus 로고
    • Engrafted chicken neural tube-derived stem cells support the innate propensity for axonal regeneration within the rat optic nerve
    • Charalambous P., Hurst L.A., Thanos S. Engrafted chicken neural tube-derived stem cells support the innate propensity for axonal regeneration within the rat optic nerve. Invest. Ophthalmol. Vis. Sci. 2008, 49:3513-3524.
    • (2008) Invest. Ophthalmol. Vis. Sci. , vol.49 , pp. 3513-3524
    • Charalambous, P.1    Hurst, L.A.2    Thanos, S.3
  • 22
    • 53449094940 scopus 로고    scopus 로고
    • Associations of seroreactivity against crystallin proteins with disease activity and cataract in patients with uveitis
    • Chen L., Holland G.N., Yu F., Levinson R.D., Lampi K.J., Horwitz J., Gordon L.K. Associations of seroreactivity against crystallin proteins with disease activity and cataract in patients with uveitis. Invest. Ophthalmol. Vis. Sci. 2008, 49:4476-4481.
    • (2008) Invest. Ophthalmol. Vis. Sci. , vol.49 , pp. 4476-4481
    • Chen, L.1    Holland, G.N.2    Yu, F.3    Levinson, R.D.4    Lampi, K.J.5    Horwitz, J.6    Gordon, L.K.7
  • 23
    • 84873465688 scopus 로고    scopus 로고
    • Ocular aldehyde dehydrogenases: protection against ultraviolet damage and maintenance of transparency for vision
    • Chen Y., Thompson D.C., Koppaka V., Jester J.V., Vasiliou V. Ocular aldehyde dehydrogenases: protection against ultraviolet damage and maintenance of transparency for vision. Prog. Retin. Eye Res. 2013, 33:28-39.
    • (2013) Prog. Retin. Eye Res. , vol.33 , pp. 28-39
    • Chen, Y.1    Thompson, D.C.2    Koppaka, V.3    Jester, J.V.4    Vasiliou, V.5
  • 24
    • 0028899440 scopus 로고
    • Decreased molecular chaperone property of alpha-crystallins due to posttranslational modifications
    • Cherian M., Abraham E.C. Decreased molecular chaperone property of alpha-crystallins due to posttranslational modifications. Biochem. Biophys. Res. Commun. 1995, 208:675-679.
    • (1995) Biochem. Biophys. Res. Commun. , vol.208 , pp. 675-679
    • Cherian, M.1    Abraham, E.C.2
  • 25
    • 18844378875 scopus 로고    scopus 로고
    • The ability of axons to regenerate their growth cones depends on axonal type and age, and is regulated by calcium, cAMP and ERK
    • Chierzi S., Ratto G.M., Verma P., Fawcett J.W. The ability of axons to regenerate their growth cones depends on axonal type and age, and is regulated by calcium, cAMP and ERK. Eur. J. Neurosci. 2005, 21:2051-2062.
    • (2005) Eur. J. Neurosci. , vol.21 , pp. 2051-2062
    • Chierzi, S.1    Ratto, G.M.2    Verma, P.3    Fawcett, J.W.4
  • 26
    • 77952066508 scopus 로고    scopus 로고
    • Up-regulation of crystallins is involved in the neuroprotective effect of wolfberry on survival of retinal ganglion cells in rat ocular hypertension model
    • Chiu K., Zhou Y., Yeung S.C., Lok C.K., Chan O.O., Chang R.C., So K.F., Chiu J.F. Up-regulation of crystallins is involved in the neuroprotective effect of wolfberry on survival of retinal ganglion cells in rat ocular hypertension model. J. Cell. Biochem 2010, 110:311-320.
    • (2010) J. Cell. Biochem , vol.110 , pp. 311-320
    • Chiu, K.1    Zhou, Y.2    Yeung, S.C.3    Lok, C.K.4    Chan, O.O.5    Chang, R.C.6    So, K.F.7    Chiu, J.F.8
  • 28
    • 35348996450 scopus 로고    scopus 로고
    • Genetic and epigenetic mechanisms of gene regulation during lens development
    • Cvekl A., Duncan M.K. Genetic and epigenetic mechanisms of gene regulation during lens development. Prog. Retin. Eye Res. 2007, 26:555-597.
    • (2007) Prog. Retin. Eye Res. , vol.26 , pp. 555-597
    • Cvekl, A.1    Duncan, M.K.2
  • 30
    • 80052591181 scopus 로고    scopus 로고
    • Transdifferentiation from cornea to lens in Xenopus laevis depends on BMP signalling and involves upregulation of Wnt signalling
    • Day R.C., Beck C.W. Transdifferentiation from cornea to lens in Xenopus laevis depends on BMP signalling and involves upregulation of Wnt signalling. BMC Dev. Biol. 2011, 11:54.
    • (2011) BMC Dev. Biol. , vol.11 , pp. 54
    • Day, R.C.1    Beck, C.W.2
  • 31
    • 84861812691 scopus 로고    scopus 로고
    • Alphab-crystallin expression in epiretinal membrane of human proliferative diabetic retinopathy
    • Dong Z., Kase S., Ando R., Fukuhara J., Saito W., Kanda A., Murata M., Noda K., Ishida S. Alphab-crystallin expression in epiretinal membrane of human proliferative diabetic retinopathy. Retina 2012, 32:1190-1196.
    • (2012) Retina , vol.32 , pp. 1190-1196
    • Dong, Z.1    Kase, S.2    Ando, R.3    Fukuhara, J.4    Saito, W.5    Kanda, A.6    Murata, M.7    Noda, K.8    Ishida, S.9
  • 32
    • 33745650321 scopus 로고    scopus 로고
    • The proteome of central and peripheral retina with progression of age-related macular degeneration
    • Ethen C.M., Reilly C., Feng X., Olsen T.W., Ferrington D.A. The proteome of central and peripheral retina with progression of age-related macular degeneration. Invest. Ophthalmol. Vis. Sci. 2006, 47:2280-2290.
    • (2006) Invest. Ophthalmol. Vis. Sci. , vol.47 , pp. 2280-2290
    • Ethen, C.M.1    Reilly, C.2    Feng, X.3    Olsen, T.W.4    Ferrington, D.A.5
  • 33
    • 24944493239 scopus 로고    scopus 로고
    • Retinal ganglion cell death and neuroprotection: involvement of the CaMKIIalpha gene
    • Fan W., Agarwal N., Kumar M.D., Cooper N.G. Retinal ganglion cell death and neuroprotection: involvement of the CaMKIIalpha gene. Brain Res. Mol. Brain Res. 2005, 139:306-316.
    • (2005) Brain Res. Mol. Brain Res. , vol.139 , pp. 306-316
    • Fan, W.1    Agarwal, N.2    Kumar, M.D.3    Cooper, N.G.4
  • 34
    • 33745726876 scopus 로고    scopus 로고
    • How inflammation promotes regeneration
    • Filbin M.T. How inflammation promotes regeneration. Nat. Neurosci. 2006, 9:715-717.
    • (2006) Nat. Neurosci. , vol.9 , pp. 715-717
    • Filbin, M.T.1
  • 35
    • 39649101076 scopus 로고    scopus 로고
    • Crystallins of the beta/gamma-superfamily mimic the effects of lens injury and promote axon regeneration
    • Fischer D., Hauk T.G., Muller A., Thanos S. Crystallins of the beta/gamma-superfamily mimic the effects of lens injury and promote axon regeneration. Mol. Cell. Neurosci. 2008, 37:471-479.
    • (2008) Mol. Cell. Neurosci. , vol.37 , pp. 471-479
    • Fischer, D.1    Hauk, T.G.2    Muller, A.3    Thanos, S.4
  • 36
    • 0035690364 scopus 로고    scopus 로고
    • Lens-injury-stimulated axonal regeneration throughout the optic pathway of adult rats
    • Fischer D., Heiduschka P., Thanos S. Lens-injury-stimulated axonal regeneration throughout the optic pathway of adult rats. Exp. Neurol. 2001, 172:257-272.
    • (2001) Exp. Neurol. , vol.172 , pp. 257-272
    • Fischer, D.1    Heiduschka, P.2    Thanos, S.3
  • 37
    • 0033753722 scopus 로고    scopus 로고
    • Cataractogenic lens injury prevents traumatic ganglion cell death and promotes axonal regeneration both in vivo and in culture
    • Fischer D., Pavlidis M., Thanos S. Cataractogenic lens injury prevents traumatic ganglion cell death and promotes axonal regeneration both in vivo and in culture. Invest. Ophthalmol. Vis. Sci. 2000, 41:3943-3954.
    • (2000) Invest. Ophthalmol. Vis. Sci. , vol.41 , pp. 3943-3954
    • Fischer, D.1    Pavlidis, M.2    Thanos, S.3
  • 38
    • 5444270047 scopus 로고    scopus 로고
    • Switching mature retinal ganglion cells to a robust growth state in vivo: gene expression and synergy with RhoA inactivation
    • Fischer D., Petkova V., Thanos S., Benowitz L.I. Switching mature retinal ganglion cells to a robust growth state in vivo: gene expression and synergy with RhoA inactivation. J. Neurosci. 2004, 24:8726-8740.
    • (2004) J. Neurosci. , vol.24 , pp. 8726-8740
    • Fischer, D.1    Petkova, V.2    Thanos, S.3    Benowitz, L.I.4
  • 39
    • 66149122699 scopus 로고    scopus 로고
    • The retinal proteome in experimental diabetic retinopathy: up-regulation of crystallins and reversal by systemic and periocular insulin
    • Fort P.E., Freeman W.M., Losiewicz M.K., Singh R.S., Gardner T.W. The retinal proteome in experimental diabetic retinopathy: up-regulation of crystallins and reversal by systemic and periocular insulin. Mol. Cell. Proteomics 2009, 8:767-779.
    • (2009) Mol. Cell. Proteomics , vol.8 , pp. 767-779
    • Fort, P.E.1    Freeman, W.M.2    Losiewicz, M.K.3    Singh, R.S.4    Gardner, T.W.5
  • 40
    • 79451469767 scopus 로고    scopus 로고
    • New focus on alpha-crystallins in retinal neurodegenerative diseases
    • Fort P.E., Lampi K.J. New focus on alpha-crystallins in retinal neurodegenerative diseases. Exp. Eye Res. 2011, 92:98-103.
    • (2011) Exp. Eye Res. , vol.92 , pp. 98-103
    • Fort, P.E.1    Lampi, K.J.2
  • 41
    • 79952802009 scopus 로고    scopus 로고
    • AlphaB-crystallin is found in detergent-resistant membrane microdomains and is secreted via exosomes from human retinal pigment epithelial cells
    • Gangalum R.K., Atanasov I.C., Zhou Z.H., Bhat S.P. AlphaB-crystallin is found in detergent-resistant membrane microdomains and is secreted via exosomes from human retinal pigment epithelial cells. J. Biol. Chem. 2011, 286:3261-3269.
    • (2011) J. Biol. Chem. , vol.286 , pp. 3261-3269
    • Gangalum, R.K.1    Atanasov, I.C.2    Zhou, Z.H.3    Bhat, S.P.4
  • 43
    • 61849122908 scopus 로고    scopus 로고
    • Genetics of crystallins: cataract and beyond
    • Graw J. Genetics of crystallins: cataract and beyond. Exp. Eye Res. 2009, 88:173-189.
    • (2009) Exp. Eye Res. , vol.88 , pp. 173-189
    • Graw, J.1
  • 44
    • 84873261787 scopus 로고    scopus 로고
    • Analysis of the cytoprotective role of alpha-crystallins in cell survival and implication of the alphaA-crystallin C-terminal extension domain in preventing Bax-induced apoptosis
    • Hamann S., Metrailler S., Schorderet D.F., Cottet S. Analysis of the cytoprotective role of alpha-crystallins in cell survival and implication of the alphaA-crystallin C-terminal extension domain in preventing Bax-induced apoptosis. PLoS One 2013, 8:e55372.
    • (2013) PLoS One , vol.8
    • Hamann, S.1    Metrailler, S.2    Schorderet, D.F.3    Cottet, S.4
  • 45
    • 38649110471 scopus 로고    scopus 로고
    • Neuroprotective and axon growth promoting effects of intraocular inflammation do not depend on oncomodulin or the presence of large numbers of activated macrophages
    • Hauk T.G., Muller A., Lee J., Schwendener R., Fischer D. Neuroprotective and axon growth promoting effects of intraocular inflammation do not depend on oncomodulin or the presence of large numbers of activated macrophages. Exp. Neurol. 2008, 209:469-482.
    • (2008) Exp. Neurol. , vol.209 , pp. 469-482
    • Hauk, T.G.1    Muller, A.2    Lee, J.3    Schwendener, R.4    Fischer, D.5
  • 46
    • 0028867349 scopus 로고
    • Beta B2-crystallin in the mammalian retina
    • Head M.W., Sedowofia K., Clayton R.M. Beta B2-crystallin in the mammalian retina. Exp. Eye Res. 1995, 61:423-428.
    • (1995) Exp. Eye Res. , vol.61 , pp. 423-428
    • Head, M.W.1    Sedowofia, K.2    Clayton, R.M.3
  • 47
    • 0037270034 scopus 로고    scopus 로고
    • Differential distribution of synaptotagmin immunoreactivity among synapses in the goldfish, salamander, and mouse retina
    • Heidelberger R., Wang M.M., Sherry D.M. Differential distribution of synaptotagmin immunoreactivity among synapses in the goldfish, salamander, and mouse retina. Vis. Neurosci. 2003, 20:37-49.
    • (2003) Vis. Neurosci. , vol.20 , pp. 37-49
    • Heidelberger, R.1    Wang, M.M.2    Sherry, D.M.3
  • 48
    • 84892631497 scopus 로고    scopus 로고
    • Strain-independent increases of crystallin proteins in the retina of type 1 diabetic rats
    • Heise E.A., Marozas L.M., Grafton S.A., Green K.M., Kirwin S.J., Fort P.E. Strain-independent increases of crystallin proteins in the retina of type 1 diabetic rats. PLoS One 2013, 8:e82520.
    • (2013) PLoS One , vol.8
    • Heise, E.A.1    Marozas, L.M.2    Grafton, S.A.3    Green, K.M.4    Kirwin, S.J.5    Fort, P.E.6
  • 50
    • 0026483279 scopus 로고
    • Alpha-crystallin can function as a molecular chaperone
    • Horwitz J. Alpha-crystallin can function as a molecular chaperone. Proc. Natl. Acad. Sci. U. S. A. 1992, 89:10449-10453.
    • (1992) Proc. Natl. Acad. Sci. U. S. A. , vol.89 , pp. 10449-10453
    • Horwitz, J.1
  • 51
    • 0037325497 scopus 로고    scopus 로고
    • Alpha-crystallin
    • Horwitz J. Alpha-crystallin. Exp. Eye Res. 2003, 76:145-153.
    • (2003) Exp. Eye Res. , vol.76 , pp. 145-153
    • Horwitz, J.1
  • 52
    • 77952299610 scopus 로고    scopus 로고
    • Expression of transcription factors and crystallin proteins during rat lens regeneration
    • Huang Y., Xie L. Expression of transcription factors and crystallin proteins during rat lens regeneration. Mol. Vis. 2010, 16:341-352.
    • (2010) Mol. Vis. , vol.16 , pp. 341-352
    • Huang, Y.1    Xie, L.2
  • 54
    • 0035895908 scopus 로고    scopus 로고
    • Phosphorylation-induced change of the oligomerization state of alpha B-crystallin
    • Ito H., Kamei K., Iwamoto I., Inaguma Y., Nohara D., Kato K. Phosphorylation-induced change of the oligomerization state of alpha B-crystallin. J. Biol. Chem. 2001, 276:5346-5352.
    • (2001) J. Biol. Chem. , vol.276 , pp. 5346-5352
    • Ito, H.1    Kamei, K.2    Iwamoto, I.3    Inaguma, Y.4    Nohara, D.5    Kato, K.6
  • 55
    • 0030613774 scopus 로고    scopus 로고
    • Phosphorylation of alphaB-crystallin in response to various types of stress
    • Ito H., Okamoto K., Nakayama H., Isobe T., Kato K. Phosphorylation of alphaB-crystallin in response to various types of stress. J. Biol. Chem. 1997, 272:29934-29941.
    • (1997) J. Biol. Chem. , vol.272 , pp. 29934-29941
    • Ito, H.1    Okamoto, K.2    Nakayama, H.3    Isobe, T.4    Kato, K.5
  • 56
    • 0027742866 scopus 로고
    • Alpha B-crystallin and 27-kd heat shock protein are regulated by stress conditions in the central nervous system and accumulate in Rosenthal fibers
    • Iwaki T., Iwaki A., Tateishi J., Sakaki Y., Goldman J.E. Alpha B-crystallin and 27-kd heat shock protein are regulated by stress conditions in the central nervous system and accumulate in Rosenthal fibers. Am. J. Pathol. 1993, 143:487-495.
    • (1993) Am. J. Pathol. , vol.143 , pp. 487-495
    • Iwaki, T.1    Iwaki, A.2    Tateishi, J.3    Sakaki, Y.4    Goldman, J.E.5
  • 57
    • 0035167113 scopus 로고    scopus 로고
    • Lens crystallins and their microbial homologs: structure, stability, and function
    • Jaenicke R., Slingsby C. Lens crystallins and their microbial homologs: structure, stability, and function. Crit. Rev. Biochem. Mol. Biol. 2001, 36:435-499.
    • (2001) Crit. Rev. Biochem. Mol. Biol. , vol.36 , pp. 435-499
    • Jaenicke, R.1    Slingsby, C.2
  • 58
    • 34447118860 scopus 로고    scopus 로고
    • Antibodies to alpha B-crystallin, vimentin, and heat shock protein 70 in aqueous humor of patients with normal tension glaucoma and IgG antibody patterns against retinal antigen in aqueous humor
    • Joachim S.C., Bruns K., Lackner K.J., Pfeiffer N., Grus F.H. Antibodies to alpha B-crystallin, vimentin, and heat shock protein 70 in aqueous humor of patients with normal tension glaucoma and IgG antibody patterns against retinal antigen in aqueous humor. Curr. Eye Res. 2007, 32:501-509.
    • (2007) Curr. Eye Res. , vol.32 , pp. 501-509
    • Joachim, S.C.1    Bruns, K.2    Lackner, K.J.3    Pfeiffer, N.4    Grus, F.H.5
  • 61
    • 0032556548 scopus 로고    scopus 로고
    • Expression of alphaB-crystallin in a mouse model of inherited retinal degeneration
    • Jones S.E., Jomary C., Grist J., Thomas M.R., Neal M.J. Expression of alphaB-crystallin in a mouse model of inherited retinal degeneration. Neuroreport 1998, 9:4161-4165.
    • (1998) Neuroreport , vol.9 , pp. 4161-4165
    • Jones, S.E.1    Jomary, C.2    Grist, J.3    Thomas, M.R.4    Neal, M.J.5
  • 62
    • 49249132708 scopus 로고    scopus 로고
    • Neurodegeneration and cellular stress in the retina and optic nerve in rat cerebral ischemia and hypoperfusion models
    • Kalesnykas G., Tuulos T., Uusitalo H., Jolkkonen J. Neurodegeneration and cellular stress in the retina and optic nerve in rat cerebral ischemia and hypoperfusion models. Neurosci 2008, 155:937-947.
    • (2008) Neurosci , vol.155 , pp. 937-947
    • Kalesnykas, G.1    Tuulos, T.2    Uusitalo, H.3    Jolkkonen, J.4
  • 64
    • 84863308955 scopus 로고    scopus 로고
    • Transcriptome analysis using next generation sequencing reveals molecular signatures of diabetic retinopathy and efficacy of candidate drugs
    • Kandpal R.P., Rajasimha H.K., Brooks M.J., Nellissery J., Wan J., Qian J., Kern T.S., Swaroop A. Transcriptome analysis using next generation sequencing reveals molecular signatures of diabetic retinopathy and efficacy of candidate drugs. Mol. Vis. 2012, 18:1123-1146.
    • (2012) Mol. Vis. , vol.18 , pp. 1123-1146
    • Kandpal, R.P.1    Rajasimha, H.K.2    Brooks, M.J.3    Nellissery, J.4    Wan, J.5    Qian, J.6    Kern, T.S.7    Swaroop, A.8
  • 65
    • 84867401896 scopus 로고    scopus 로고
    • Novel roles for alpha-crystallins in retinal function and disease
    • Kannan R., Sreekumar P.G., Hinton D.R. Novel roles for alpha-crystallins in retinal function and disease. Prog. Retin. Eye Res. 2012, 31:576-604.
    • (2012) Prog. Retin. Eye Res. , vol.31 , pp. 576-604
    • Kannan, R.1    Sreekumar, P.G.2    Hinton, D.R.3
  • 67
    • 79960765391 scopus 로고    scopus 로고
    • Increased expression of alphaA-crystallin in human diabetic eye
    • Kase S., Ishida S., Rao N.A. Increased expression of alphaA-crystallin in human diabetic eye. Int. J. Mol. Med. 2011, 28:505-511.
    • (2011) Int. J. Mol. Med. , vol.28 , pp. 505-511
    • Kase, S.1    Ishida, S.2    Rao, N.A.3
  • 68
    • 84855667050 scopus 로고    scopus 로고
    • Expression of alpha-crystallin in the retina of human sympathetic ophthalmia
    • Kase S., Meghpara B.B., Ishida S., Rao N.A. Expression of alpha-crystallin in the retina of human sympathetic ophthalmia. Mol. Med. Rep. 2012, 5:395-399.
    • (2012) Mol. Med. Rep. , vol.5 , pp. 395-399
    • Kase, S.1    Meghpara, B.B.2    Ishida, S.3    Rao, N.A.4
  • 69
    • 38449113264 scopus 로고    scopus 로고
    • Multiple mechanisms and functions of maf transcription factors in the regulation of tissue-specific genes
    • Kataoka K. Multiple mechanisms and functions of maf transcription factors in the regulation of tissue-specific genes. J. Biochem. 2007, 141:775-781.
    • (2007) J. Biochem. , vol.141 , pp. 775-781
    • Kataoka, K.1
  • 70
    • 78651273504 scopus 로고    scopus 로고
    • Expression of alphaB-crystallin in the peripapillary glial cells of the developing chick retina
    • Kim J.Y., Sohn H.J., Lee E.Y., Goo Y.S., Kim D.W., Seo J.H. Expression of alphaB-crystallin in the peripapillary glial cells of the developing chick retina. Neurochem. Res. 2011, 36:76-82.
    • (2011) Neurochem. Res. , vol.36 , pp. 76-82
    • Kim, J.Y.1    Sohn, H.J.2    Lee, E.Y.3    Goo, Y.S.4    Kim, D.W.5    Seo, J.H.6
  • 71
    • 84866734775 scopus 로고    scopus 로고
    • AlphaB-crystallin is expressed in myelinating oligodendrocytes of the developing and adult avian retina
    • Kim J.Y., Song S.H., Kim H.N., Kim D.W., Sohn H.J., Lee E.Y., Cho S.S., Seo J.H. AlphaB-crystallin is expressed in myelinating oligodendrocytes of the developing and adult avian retina. Neurochem. Res. 2012, 37:2135-2142.
    • (2012) Neurochem. Res. , vol.37 , pp. 2135-2142
    • Kim, J.Y.1    Song, S.H.2    Kim, H.N.3    Kim, D.W.4    Sohn, H.J.5    Lee, E.Y.6    Cho, S.S.7    Seo, J.H.8
  • 73
    • 84866083771 scopus 로고    scopus 로고
    • Reduction of experimental diabetic vascular leakage and pericyte apoptosis in mice by delivery of alphaA-crystallin with a recombinant adenovirus
    • Kim Y.H., Park S.Y., Park J., Kim Y.S., Hwang E.M., Park J.Y., Roh G.S., Kim H.J., Kang S.S., Cho G.J., Choi W.S. Reduction of experimental diabetic vascular leakage and pericyte apoptosis in mice by delivery of alphaA-crystallin with a recombinant adenovirus. Diabetologia 2012, 55:2835-2844.
    • (2012) Diabetologia , vol.55 , pp. 2835-2844
    • Kim, Y.H.1    Park, S.Y.2    Park, J.3    Kim, Y.S.4    Hwang, E.M.5    Park, J.Y.6    Roh, G.S.7    Kim, H.J.8    Kang, S.S.9    Cho, G.J.10    Choi, W.S.11
  • 74
    • 0032479151 scopus 로고    scopus 로고
    • Regulation of expression within a gene family. The case of the rat gammaB- and gammaD-crystallin promoters
    • Klok E.J., van Genesen S.T., Civil A., Schoenmakers J.G., Lubsen N.H. Regulation of expression within a gene family. The case of the rat gammaB- and gammaD-crystallin promoters. J. Biol. Chem. 1998, 273:17206-17215.
    • (1998) J. Biol. Chem. , vol.273 , pp. 17206-17215
    • Klok, E.J.1    van Genesen, S.T.2    Civil, A.3    Schoenmakers, J.G.4    Lubsen, N.H.5
  • 75
    • 0141961841 scopus 로고    scopus 로고
    • Calmodulin gene expression in the neural retina of the adult rat
    • Kovacs B., Gulya K. Calmodulin gene expression in the neural retina of the adult rat. Life Sci. 2003, 73:3213-3224.
    • (2003) Life Sci. , vol.73 , pp. 3213-3224
    • Kovacs, B.1    Gulya, K.2
  • 77
    • 78449235139 scopus 로고    scopus 로고
    • Long-distance axon regeneration in the mature optic nerve: contributions of oncomodulin, cAMP, and pten gene deletion
    • Kurimoto T., Yin Y., Omura K., Gilbert H.Y., Kim D., Cen L.P., Moko L., Kugler S., Benowitz L.I. Long-distance axon regeneration in the mature optic nerve: contributions of oncomodulin, cAMP, and pten gene deletion. J. Neurosci. 2010, 30:15654-15663.
    • (2010) J. Neurosci. , vol.30 , pp. 15654-15663
    • Kurimoto, T.1    Yin, Y.2    Omura, K.3    Gilbert, H.Y.4    Kim, D.5    Cen, L.P.6    Moko, L.7    Kugler, S.8    Benowitz, L.I.9
  • 79
    • 78650253406 scopus 로고    scopus 로고
    • Light-induced phosphorylation of crystallins in the retinal pigment epithelium
    • Lee H., Chung H., Lee S.H., Jahng W.J. Light-induced phosphorylation of crystallins in the retinal pigment epithelium. Int. J. Biol. Macromol. 2011, 48:194-201.
    • (2011) Int. J. Biol. Macromol. , vol.48 , pp. 194-201
    • Lee, H.1    Chung, H.2    Lee, S.H.3    Jahng, W.J.4
  • 80
    • 0034659957 scopus 로고    scopus 로고
    • Lens injury stimulates axon regeneration in the mature rat optic nerve
    • Leon S., Yin Y., Nguyen J., Irwin N., Benowitz L.I. Lens injury stimulates axon regeneration in the mature rat optic nerve. J. Neurosci. 2000, 20:4615-4626.
    • (2000) J. Neurosci. , vol.20 , pp. 4615-4626
    • Leon, S.1    Yin, Y.2    Nguyen, J.3    Irwin, N.4    Benowitz, L.I.5
  • 81
    • 33947159103 scopus 로고    scopus 로고
    • Elongation of axons during regeneration involves retinal crystallin beta b2 (crybb2)
    • Liedtke T., Schwamborn J.C., Schroer U., Thanos S. Elongation of axons during regeneration involves retinal crystallin beta b2 (crybb2). Mol. Cell. Proteomics 2007, 6:895-907.
    • (2007) Mol. Cell. Proteomics , vol.6 , pp. 895-907
    • Liedtke, T.1    Schwamborn, J.C.2    Schroer, U.3    Thanos, S.4
  • 82
    • 77951159399 scopus 로고    scopus 로고
    • Intraretinal crystalline deposits in neovascular age-related macular degeneration
    • Lima L.H., Freund K.B., Klancnik J.M., Spaide R.F. Intraretinal crystalline deposits in neovascular age-related macular degeneration. Retina 2010, 30:542-547.
    • (2010) Retina , vol.30 , pp. 542-547
    • Lima, L.H.1    Freund, K.B.2    Klancnik, J.M.3    Spaide, R.F.4
  • 84
    • 4444281383 scopus 로고    scopus 로고
    • Human alphaA- and alphaB-crystallins prevent UVA-induced apoptosis through regulation of PKCalpha, RAF/MEK/ERK and AKT signaling pathways
    • Liu J.P., Schlosser R., Ma W.Y., Dong Z., Feng H., Liu L., Huang X.Q., Liu Y., Li D.W. Human alphaA- and alphaB-crystallins prevent UVA-induced apoptosis through regulation of PKCalpha, RAF/MEK/ERK and AKT signaling pathways. Exp. Eye Res. 2004, 79:393-403.
    • (2004) Exp. Eye Res. , vol.79 , pp. 393-403
    • Liu, J.P.1    Schlosser, R.2    Ma, W.Y.3    Dong, Z.4    Feng, H.5    Liu, L.6    Huang, X.Q.7    Liu, Y.8    Li, D.W.9
  • 85
    • 18844421914 scopus 로고    scopus 로고
    • Lens injury stimulates adult mouse retinal ganglion cell axon regeneration via both macrophage- and lens-derived factors
    • Lorber B., Berry M., Logan A. Lens injury stimulates adult mouse retinal ganglion cell axon regeneration via both macrophage- and lens-derived factors. Eur. J. Neurosci. 2005, 21:2029-2034.
    • (2005) Eur. J. Neurosci. , vol.21 , pp. 2029-2034
    • Lorber, B.1    Berry, M.2    Logan, A.3
  • 86
    • 80054788049 scopus 로고    scopus 로고
    • Diabetes impairs the neuroprotective properties of retinal alpha-crystallins
    • Losiewicz M.K., Fort P.E. Diabetes impairs the neuroprotective properties of retinal alpha-crystallins. Invest. Ophthalmol. Vis. Sci. 2011, 52:5034-5042.
    • (2011) Invest. Ophthalmol. Vis. Sci. , vol.52 , pp. 5034-5042
    • Losiewicz, M.K.1    Fort, P.E.2
  • 88
    • 0024218965 scopus 로고
    • The evolution of lenticular proteins: the beta- and gamma-crystallin super gene family
    • Lubsen N.H., Aarts H.J., Schoenmakers J.G. The evolution of lenticular proteins: the beta- and gamma-crystallin super gene family. Prog. Biophys. Mol. Biol. 1988, 51:47-76.
    • (1988) Prog. Biophys. Mol. Biol. , vol.51 , pp. 47-76
    • Lubsen, N.H.1    Aarts, H.J.2    Schoenmakers, J.G.3
  • 89
    • 80055015834 scopus 로고    scopus 로고
    • BetaA3/A1-Crystallin controls anoikis-mediated cell death in astrocytes by modulating PI3K/AKT/mTOR and ERK survival pathways through the PKD/Bit1-signaling axis
    • Ma B., Sen T., Asnaghi L., Valapala M., Yang F., Hose S., McLeod D.S., Lu Y., Eberhart C., Zigler J.S., Sinha D. betaA3/A1-Crystallin controls anoikis-mediated cell death in astrocytes by modulating PI3K/AKT/mTOR and ERK survival pathways through the PKD/Bit1-signaling axis. Cell. Death Dis. 2011, 2:e217.
    • (2011) Cell. Death Dis. , vol.2
    • Ma, B.1    Sen, T.2    Asnaghi, L.3    Valapala, M.4    Yang, F.5    Hose, S.6    McLeod, D.S.7    Lu, Y.8    Eberhart, C.9    Zigler, J.S.10    Sinha, D.11
  • 90
    • 0242287938 scopus 로고    scopus 로고
    • Cell death triggered by a novel mutation in the alphaA-crystallin gene underlies autosomal dominant cataract linked to chromosome 21q
    • Mackay D.S., Andley U.P., Shiels A. Cell death triggered by a novel mutation in the alphaA-crystallin gene underlies autosomal dominant cataract linked to chromosome 21q. Eur. J. Hum. Genet. 2003, 11:784-793.
    • (2003) Eur. J. Hum. Genet. , vol.11 , pp. 784-793
    • Mackay, D.S.1    Andley, U.P.2    Shiels, A.3
  • 91
    • 1842452643 scopus 로고    scopus 로고
    • A missense mutation in the gammaD crystallin gene (CRYGD) associated with autosomal dominant "coral-like" cataract linked to chromosome 2q
    • Mackay D.S., Andley U.P., Shiels A. A missense mutation in the gammaD crystallin gene (CRYGD) associated with autosomal dominant "coral-like" cataract linked to chromosome 2q. Mol. Vis. 2004, 10:155-162.
    • (2004) Mol. Vis. , vol.10 , pp. 155-162
    • Mackay, D.S.1    Andley, U.P.2    Shiels, A.3
  • 92
    • 18844362688 scopus 로고    scopus 로고
    • Alpha-Crystallin localizes to the leading edges of migrating lens epithelial cells
    • Maddala R., Rao V.P. alpha-Crystallin localizes to the leading edges of migrating lens epithelial cells. Exp. Cell. Res. 2005, 306:203-215.
    • (2005) Exp. Cell. Res. , vol.306 , pp. 203-215
    • Maddala, R.1    Rao, V.P.2
  • 94
    • 2442681777 scopus 로고    scopus 로고
    • Human alphaA- and alphaB-crystallins bind to Bax and Bcl-X(S) to sequester their translocation during staurosporine-induced apoptosis
    • Mao Y.W., Liu J.P., Xiang H., Li D.W. Human alphaA- and alphaB-crystallins bind to Bax and Bcl-X(S) to sequester their translocation during staurosporine-induced apoptosis. Cell. Death Differ. 2004, 11:512-526.
    • (2004) Cell. Death Differ. , vol.11 , pp. 512-526
    • Mao, Y.W.1    Liu, J.P.2    Xiang, H.3    Li, D.W.4
  • 95
    • 0023389564 scopus 로고
    • Gamma-crystallins of the human eye lens: expression analysis of five members of the gene family
    • Meakin S.O., Du R.P., Tsui L.C., Breitman M.L. Gamma-crystallins of the human eye lens: expression analysis of five members of the gene family. Mol. Cell. Biol. 1987, 7:2671-2679.
    • (1987) Mol. Cell. Biol. , vol.7 , pp. 2671-2679
    • Meakin, S.O.1    Du, R.P.2    Tsui, L.C.3    Breitman, M.L.4
  • 96
    • 33646591274 scopus 로고    scopus 로고
    • Gene expression and discovery during lens regeneration in mouse: regulation of epithelial to mesenchymal transition and lens differentiation
    • Medvedovic M., Tomlinson C.R., Call M.K., Grogg M., Tsonis P.A. Gene expression and discovery during lens regeneration in mouse: regulation of epithelial to mesenchymal transition and lens differentiation. Mol. Vis. 2006, 12:422-440.
    • (2006) Mol. Vis. , vol.12 , pp. 422-440
    • Medvedovic, M.1    Tomlinson, C.R.2    Call, M.K.3    Grogg, M.4    Tsonis, P.A.5
  • 97
    • 0029933741 scopus 로고    scopus 로고
    • Human hsp27, Drosophila hsp27 and human alphaB-crystallin expression-mediated increase in glutathione is essential for the protective activity of these proteins against TNFalpha-induced cell death
    • Mehlen P., Kretz-Remy C., Preville X., Arrigo A.P. Human hsp27, Drosophila hsp27 and human alphaB-crystallin expression-mediated increase in glutathione is essential for the protective activity of these proteins against TNFalpha-induced cell death. EMBO J. 1996, 15:2695-2706.
    • (1996) EMBO J. , vol.15 , pp. 2695-2706
    • Mehlen, P.1    Kretz-Remy, C.2    Preville, X.3    Arrigo, A.P.4
  • 98
    • 43049092658 scopus 로고    scopus 로고
    • Proteomic analysis of rat retina in a steroid-induced ocular hypertension model: potential vulnerability to oxidative stress
    • Miyara N., Shinzato M., Yamashiro Y., Iwamatsu A., Kariya K., Sawaguchi S. Proteomic analysis of rat retina in a steroid-induced ocular hypertension model: potential vulnerability to oxidative stress. Jpn. J. Ophthalmol. 2008, 52:84-90.
    • (2008) Jpn. J. Ophthalmol. , vol.52 , pp. 84-90
    • Miyara, N.1    Shinzato, M.2    Yamashiro, Y.3    Iwamatsu, A.4    Kariya, K.5    Sawaguchi, S.6
  • 100
    • 33645538666 scopus 로고    scopus 로고
    • Caspase-dependent secondary lens fiber cell disintegration in alphaA-/alphaB-crystallin double-knockout mice
    • Morozov V., Wawrousek E.F. Caspase-dependent secondary lens fiber cell disintegration in alphaA-/alphaB-crystallin double-knockout mice. Development 2006, 133:813-821.
    • (2006) Development , vol.133 , pp. 813-821
    • Morozov, V.1    Wawrousek, E.F.2
  • 101
    • 84871991465 scopus 로고    scopus 로고
    • Cell penetration peptides for enhanced entry of alphaB-crystallin into lens cells
    • Müller N.H., Ammar D.A., Petrash J.M. Cell penetration peptides for enhanced entry of alphaB-crystallin into lens cells. Invest. Ophthalmol. Vis. Sci. 2013, 54:2-8.
    • (2013) Invest. Ophthalmol. Vis. Sci. , vol.54 , pp. 2-8
    • Müller, N.H.1    Ammar, D.A.2    Petrash, J.M.3
  • 102
    • 68349103136 scopus 로고    scopus 로고
    • The role of alphaA- and alphaB-crystallins in the survival of retinal ganglion cells after optic nerve axotomy
    • Munemasa Y., Kwong J.M., Caprioli J., Piri N. The role of alphaA- and alphaB-crystallins in the survival of retinal ganglion cells after optic nerve axotomy. Invest. Ophthalmol. Vis. Sci. 2009, 50:3869-3875.
    • (2009) Invest. Ophthalmol. Vis. Sci. , vol.50 , pp. 3869-3875
    • Munemasa, Y.1    Kwong, J.M.2    Caprioli, J.3    Piri, N.4
  • 103
    • 84866707491 scopus 로고    scopus 로고
    • Bilberries potentially alleviate stress-related retinal gene expression induced by a high-fat diet in mice
    • Mykkanen O.T., Kalesnykas G., Adriaens M., Evelo C.T., Torronen R., Kaarniranta K. Bilberries potentially alleviate stress-related retinal gene expression induced by a high-fat diet in mice. Mol. Vis. 2012, 18:2338-2351.
    • (2012) Mol. Vis. , vol.18 , pp. 2338-2351
    • Mykkanen, O.T.1    Kalesnykas, G.2    Adriaens, M.3    Evelo, C.T.4    Torronen, R.5    Kaarniranta, K.6
  • 104
    • 23744438797 scopus 로고    scopus 로고
    • Dicarbonyl stress and apoptosis of vascular cells: prevention by alphaB-crystallin
    • Nagaraj R.H., Oya-Ito T., Bhat M., Liu B. Dicarbonyl stress and apoptosis of vascular cells: prevention by alphaB-crystallin. Ann. N. Y. Acad. Sci. 2005, 1043:158-165.
    • (2005) Ann. N. Y. Acad. Sci. , vol.1043 , pp. 158-165
    • Nagaraj, R.H.1    Oya-Ito, T.2    Bhat, M.3    Liu, B.4
  • 105
    • 33750415482 scopus 로고    scopus 로고
    • Retinal gene profiling in a hereditary rodent model of elevated intraocular pressure
    • Naskar R., Thanos S. Retinal gene profiling in a hereditary rodent model of elevated intraocular pressure. Mol. Vis. 2006, 12:1199-1210.
    • (2006) Mol. Vis. , vol.12 , pp. 1199-1210
    • Naskar, R.1    Thanos, S.2
  • 106
    • 33645401537 scopus 로고    scopus 로고
    • Proteomics of the retinal pigment epithelium reveals altered protein expression at progressive stages of age-related macular degeneration
    • Nordgaard C.L., Berg K.M., Kapphahn R.J., Reilly C., Feng X., Olsen T.W., Ferrington D.A. Proteomics of the retinal pigment epithelium reveals altered protein expression at progressive stages of age-related macular degeneration. Invest. Ophthalmol. Vis. Sci. 2006, 47:815-822.
    • (2006) Invest. Ophthalmol. Vis. Sci. , vol.47 , pp. 815-822
    • Nordgaard, C.L.1    Berg, K.M.2    Kapphahn, R.J.3    Reilly, C.4    Feng, X.5    Olsen, T.W.6    Ferrington, D.A.7
  • 109
    • 79958761661 scopus 로고    scopus 로고
    • Functional rescue of experimental ischemic optic neuropathy with alphaB-crystallin
    • Pangratz-Fuehrer S., Kaur K., Ousman S.S., Steinman L., Liao Y.J. Functional rescue of experimental ischemic optic neuropathy with alphaB-crystallin. Eye (Lond.) 2011, 25:809-817.
    • (2011) Eye (Lond.) , vol.25 , pp. 809-817
    • Pangratz-Fuehrer, S.1    Kaur, K.2    Ousman, S.S.3    Steinman, L.4    Liao, Y.J.5
  • 112
    • 0023214514 scopus 로고
    • Progressive changes in lens crystallin glycation and high-molecular-weight aggregate formation leading to cataract development in streptozotocin-diabetic rats
    • Perry R.E., Swamy M.S., Abraham E.C. Progressive changes in lens crystallin glycation and high-molecular-weight aggregate formation leading to cataract development in streptozotocin-diabetic rats. Exp. Eye Res. 1987, 44:269-282.
    • (1987) Exp. Eye Res. , vol.44 , pp. 269-282
    • Perry, R.E.1    Swamy, M.S.2    Abraham, E.C.3
  • 113
    • 0026754720 scopus 로고
    • Lens crystallins. Innovation associated with changes in gene regulation
    • Piatigorsky J. Lens crystallins. Innovation associated with changes in gene regulation. J. Biol. Chem. 1992, 267:4277-4280.
    • (1992) J. Biol. Chem. , vol.267 , pp. 4277-4280
    • Piatigorsky, J.1
  • 114
    • 84888007484 scopus 로고    scopus 로고
    • Crystallins in retinal ganglion cell survival and regeneration
    • Piri N., Kwong J.M., Caprioli J. Crystallins in retinal ganglion cell survival and regeneration. Mol. Neurobiol. 2013, 48:819-828.
    • (2013) Mol. Neurobiol. , vol.48 , pp. 819-828
    • Piri, N.1    Kwong, J.M.2    Caprioli, J.3
  • 115
    • 33847677726 scopus 로고    scopus 로고
    • Modulation of alpha and beta crystallin expression in rat retinas with ocular hypertension-induced ganglion cell degeneration
    • Piri N., Song M., Kwong J.M., Caprioli J. Modulation of alpha and beta crystallin expression in rat retinas with ocular hypertension-induced ganglion cell degeneration. Brain Res. 2007, 1141:1-9.
    • (2007) Brain Res. , vol.1141 , pp. 1-9
    • Piri, N.1    Song, M.2    Kwong, J.M.3    Caprioli, J.4
  • 116
    • 84874485984 scopus 로고    scopus 로고
    • Crystallins are regulated biomarkers for monitoring topical therapy of glaucomatous optic neuropathy
    • Prokosch V., Schallenberg M., Thanos S. Crystallins are regulated biomarkers for monitoring topical therapy of glaucomatous optic neuropathy. PLoS One 2013, 8:e49730.
    • (2013) PLoS One , vol.8
    • Prokosch, V.1    Schallenberg, M.2    Thanos, S.3
  • 117
    • 79955464068 scopus 로고    scopus 로고
    • Concomitant cellular reactions in optic nerve siderosis existing for 30 years
    • Prokosch V., Spieker T., Merte R.L., Thanos S. Concomitant cellular reactions in optic nerve siderosis existing for 30 years. Ophthalmologe 2011, 108:372-377.
    • (2011) Ophthalmologe , vol.108 , pp. 372-377
    • Prokosch, V.1    Spieker, T.2    Merte, R.L.3    Thanos, S.4
  • 118
    • 84859114916 scopus 로고    scopus 로고
    • Small heat shock protein alphaA-crystallin prevents photoreceptor degeneration in experimental autoimmune uveitis
    • Rao N.A., Saraswathy S., Pararajasegaram G., Bhat S.P. Small heat shock protein alphaA-crystallin prevents photoreceptor degeneration in experimental autoimmune uveitis. PLoS One 2012, 7:e33582.
    • (2012) PLoS One , vol.7
    • Rao, N.A.1    Saraswathy, S.2    Pararajasegaram, G.3    Bhat, S.P.4
  • 119
    • 41949083991 scopus 로고    scopus 로고
    • Elevated retina-specific expression of the small heat shock protein, alphaA-crystallin, is associated with photoreceptor protection in experimental uveitis
    • Rao N.A., Saraswathy S., Wu G.S., Katselis G.S., Wawrousek E.F., Bhat S. Elevated retina-specific expression of the small heat shock protein, alphaA-crystallin, is associated with photoreceptor protection in experimental uveitis. Invest. Ophthalmol. Vis. Sci. 2008, 49:1161-1171.
    • (2008) Invest. Ophthalmol. Vis. Sci. , vol.49 , pp. 1161-1171
    • Rao, N.A.1    Saraswathy, S.2    Wu, G.S.3    Katselis, G.S.4    Wawrousek, E.F.5    Bhat, S.6
  • 121
    • 0006607248 scopus 로고    scopus 로고
    • Dementia, gliosis and expression of the small heat shock proteins hsp27 and alpha B-crystallin in Parkinson's disease
    • Renkawek K., Stege G.J., Bosman G.J. Dementia, gliosis and expression of the small heat shock proteins hsp27 and alpha B-crystallin in Parkinson's disease. Neuroreport 1999, 10:2273-2276.
    • (1999) Neuroreport , vol.10 , pp. 2273-2276
    • Renkawek, K.1    Stege, G.J.2    Bosman, G.J.3
  • 123
    • 57149106112 scopus 로고    scopus 로고
    • Axonal regeneration in the organotypically cultured monkey retina: biological aspects, dependence on substrates and age-related proteomic profiling
    • Rose K., Schroer U., Volk G.F., Schlatt S., Konig S., Feigenspan A., Thanos S. Axonal regeneration in the organotypically cultured monkey retina: biological aspects, dependence on substrates and age-related proteomic profiling. Rest. Neurol. Neurosci. 2008, 26:249-266.
    • (2008) Rest. Neurol. Neurosci. , vol.26 , pp. 249-266
    • Rose, K.1    Schroer, U.2    Volk, G.F.3    Schlatt, S.4    Konig, S.5    Feigenspan, A.6    Thanos, S.7
  • 125
    • 77955855042 scopus 로고    scopus 로고
    • The role of TLR4 in photoreceptor {alpha}a crystallin upregulation during early experimental autoimmune uveitis
    • Saraswathy S., Nguyen A.M., Rao N.A. The role of TLR4 in photoreceptor {alpha}a crystallin upregulation during early experimental autoimmune uveitis. Invest. Ophthalmol. Vis. Sci. 2010, 51:3680-3686.
    • (2010) Invest. Ophthalmol. Vis. Sci. , vol.51 , pp. 3680-3686
    • Saraswathy, S.1    Nguyen, A.M.2    Rao, N.A.3
  • 126
    • 73349101064 scopus 로고    scopus 로고
    • Mitochondrial proteomics in experimental autoimmune uveitis oxidative stress
    • Saraswathy S., Rao N.A. Mitochondrial proteomics in experimental autoimmune uveitis oxidative stress. Invest. Ophthalmol. Vis. Sci. 2009, 50:5559-5566.
    • (2009) Invest. Ophthalmol. Vis. Sci. , vol.50 , pp. 5559-5566
    • Saraswathy, S.1    Rao, N.A.2
  • 127
    • 0028254544 scopus 로고
    • Expression of the alpha-crystallin/small heat-shock protein/molecular chaperone genes in the lens and other tissues
    • Sax C.M., Piatigorsky J. Expression of the alpha-crystallin/small heat-shock protein/molecular chaperone genes in the lens and other tissues. Adv. Enzymol. Relat. Areas Mol. Biol. 1994, 69:155-201.
    • (1994) Adv. Enzymol. Relat. Areas Mol. Biol. , vol.69 , pp. 155-201
    • Sax, C.M.1    Piatigorsky, J.2
  • 128
    • 0032580087 scopus 로고    scopus 로고
    • Cloning and mapping the mouse Crygs gene and non-lens expression of [gamma]S-crystallin
    • Sinha D., Esumi N., Jaworski C., Kozak C.A., Pierce E., Wistow G. Cloning and mapping the mouse Crygs gene and non-lens expression of [gamma]S-crystallin. Mol. Vis. 1998, 4:8.
    • (1998) Mol. Vis. , vol.4 , pp. 8
    • Sinha, D.1    Esumi, N.2    Jaworski, C.3    Kozak, C.A.4    Pierce, E.5    Wistow, G.6
  • 131
    • 84896723187 scopus 로고    scopus 로고
    • Proteomic interactions in the mouse vitreous-retina complex
    • Skeie J.M., Mahajan V.B. Proteomic interactions in the mouse vitreous-retina complex. PLoS One 2013, 8:e82140.
    • (2013) PLoS One , vol.8
    • Skeie, J.M.1    Mahajan, V.B.2
  • 132
    • 78149428751 scopus 로고    scopus 로고
    • AlphaB crystallin is apically secreted within exosomes by polarized human retinal pigment epithelium and provides neuroprotection to adjacent cells
    • Sreekumar P.G., Kannan R., Kitamura M., Spee C., Barron E., Ryan S.J., Hinton D.R. alphaB crystallin is apically secreted within exosomes by polarized human retinal pigment epithelium and provides neuroprotection to adjacent cells. PLoS One 2010, 5:e12578.
    • (2010) PLoS One , vol.5
    • Sreekumar, P.G.1    Kannan, R.2    Kitamura, M.3    Spee, C.4    Barron, E.5    Ryan, S.J.6    Hinton, D.R.7
  • 133
    • 84858611567 scopus 로고    scopus 로고
    • Mechanism of RPE cell death in alpha-crystallin deficient mice: a novel and critical role for MRP1-mediated GSH efflux
    • Sreekumar P.G., Spee C., Ryan S.J., Cole S.P., Kannan R., Hinton D.R. Mechanism of RPE cell death in alpha-crystallin deficient mice: a novel and critical role for MRP1-mediated GSH efflux. PLoS One 2012, 7:e33420.
    • (2012) PLoS One , vol.7
    • Sreekumar, P.G.1    Spee, C.2    Ryan, S.J.3    Cole, S.P.4    Kannan, R.5    Hinton, D.R.6
  • 134
    • 0032545223 scopus 로고    scopus 로고
    • Degradation of gamma D- and gamma s-crystallins in human lenses
    • Srivastava O.P., Srivastava K. Degradation of gamma D- and gamma s-crystallins in human lenses. Biochem. Biophys. Res. Commun. 1998, 253:288-294.
    • (1998) Biochem. Biophys. Res. Commun. , vol.253 , pp. 288-294
    • Srivastava, O.P.1    Srivastava, K.2
  • 135
    • 0031766786 scopus 로고    scopus 로고
    • Purification of gamma-crystallin from human lenses by acetone precipitation method
    • Srivastava O.P., Srivastava K. Purification of gamma-crystallin from human lenses by acetone precipitation method. Curr. Eye Res. 1998, 17:1074-1081.
    • (1998) Curr. Eye Res. , vol.17 , pp. 1074-1081
    • Srivastava, O.P.1    Srivastava, K.2
  • 136
    • 0034492713 scopus 로고    scopus 로고
    • Heat shock protein-based novel immunotherapies
    • Srivastava P.K. Heat shock protein-based novel immunotherapies. Drug. News Perspect. 2000, 13:517-522.
    • (2000) Drug. News Perspect. , vol.13 , pp. 517-522
    • Srivastava, P.K.1
  • 139
    • 27444443845 scopus 로고    scopus 로고
    • Lens epithelium supports axonal regeneration of retinal ganglion cells in a coculture model in vitro
    • Stupp T., Pavlidis M., Busse H., Thanos S. Lens epithelium supports axonal regeneration of retinal ganglion cells in a coculture model in vitro. Exp. Eye Res. 2005, 81:530-538.
    • (2005) Exp. Eye Res. , vol.81 , pp. 530-538
    • Stupp, T.1    Pavlidis, M.2    Busse, H.3    Thanos, S.4
  • 141
    • 0027400290 scopus 로고
    • Glycation mediated lens crystallin aggregation and cross-linking by various sugars and sugar phosphates in vitro
    • Swamy M.S., Tsai C., Abraham A., Abraham E.C. Glycation mediated lens crystallin aggregation and cross-linking by various sugars and sugar phosphates in vitro. Exp. Eye Res. 1993, 56:177-185.
    • (1993) Exp. Eye Res. , vol.56 , pp. 177-185
    • Swamy, M.S.1    Tsai, C.2    Abraham, A.3    Abraham, E.C.4
  • 142
    • 0031789541 scopus 로고    scopus 로고
    • Autoantibodies to small heat shock proteins in glaucoma
    • Tezel G., Seigel G.M., Wax M.B. Autoantibodies to small heat shock proteins in glaucoma. Invest. Ophthalmol. Vis. Sci. 1998, 39:2277-2287.
    • (1998) Invest. Ophthalmol. Vis. Sci. , vol.39 , pp. 2277-2287
    • Tezel, G.1    Seigel, G.M.2    Wax, M.B.3
  • 144
    • 26444583909 scopus 로고    scopus 로고
    • Molecular composition of drusen and possible involvement of anti-retinal autoimmunity in two different forms of macular degeneration in cynomolgus monkey (Macaca fascicularis)
    • Umeda S., Suzuki M.T., Okamoto H., Ono F., Mizota A., Terao K., Yoshikawa Y., Tanaka Y., Iwata T. Molecular composition of drusen and possible involvement of anti-retinal autoimmunity in two different forms of macular degeneration in cynomolgus monkey (Macaca fascicularis). FASEB J. 2005, 19:1683-1685.
    • (2005) FASEB J. , vol.19 , pp. 1683-1685
    • Umeda, S.1    Suzuki, M.T.2    Okamoto, H.3    Ono, F.4    Mizota, A.5    Terao, K.6    Yoshikawa, Y.7    Tanaka, Y.8    Iwata, T.9
  • 145
    • 0034987735 scopus 로고    scopus 로고
    • A unique form of autosomal dominant cataract explained by gene conversion between beta-crystallin B2 and its pseudogene
    • Vanita, Sarhadi V., Reis A., Jung M., Singh D., Sperling K., Singh J.R., Burger J. A unique form of autosomal dominant cataract explained by gene conversion between beta-crystallin B2 and its pseudogene. J. Med. Genet. 2001, 38:392-396.
    • (2001) J. Med. Genet. , vol.38 , pp. 392-396
    • Vanita Sarhadi, V.1    Reis, A.2    Jung, M.3    Singh, D.4    Sperling, K.5    Singh, J.R.6    Burger, J.7
  • 147
    • 0023410632 scopus 로고
    • Axonal regeneration and synapse formation in the superior colliculus by retinal ganglion cells in the adult rat
    • Vidal-Sanz M., Bray G.M., Villegas-Perez M.P., Thanos S., Aguayo A.J. Axonal regeneration and synapse formation in the superior colliculus by retinal ganglion cells in the adult rat. J. Neurosci. 1987, 7:2894-2909.
    • (1987) J. Neurosci. , vol.7 , pp. 2894-2909
    • Vidal-Sanz, M.1    Bray, G.M.2    Villegas-Perez, M.P.3    Thanos, S.4    Aguayo, A.J.5
  • 148
    • 4644279714 scopus 로고    scopus 로고
    • Expression and regulation of alpha-, beta-, and gamma-crystallins in mammalian lens epithelial cells
    • Wang X., Garcia C.M., Shui Y.B., Beebe D.C. Expression and regulation of alpha-, beta-, and gamma-crystallins in mammalian lens epithelial cells. Invest. Ophthalmol. Vis. Sci. 2004, 45:3608-3619.
    • (2004) Invest. Ophthalmol. Vis. Sci. , vol.45 , pp. 3608-3619
    • Wang, X.1    Garcia, C.M.2    Shui, Y.B.3    Beebe, D.C.4
  • 149
    • 66149097425 scopus 로고    scopus 로고
    • In vitro study of the effects of lens extract on rat retinal neuron survival and neurite outgrowth
    • Wang Y., Wang Y., Wang D., Wu N., Liu D., Yin Z., Zhu M. In vitro study of the effects of lens extract on rat retinal neuron survival and neurite outgrowth. Ophthalmic Res. 2009, 42:29-35.
    • (2009) Ophthalmic Res. , vol.42 , pp. 29-35
    • Wang, Y.1    Wang, Y.2    Wang, D.3    Wu, N.4    Liu, D.5    Yin, Z.6    Zhu, M.7
  • 150
    • 35649011558 scopus 로고    scopus 로고
    • Comparative proteome analysis of neural retinas from type 2 diabetic rats by two-dimensional electrophoresis
    • Wang Y.D., Wu J.D., Jiang Z.L., Wang Y.B., Wang X.H., Liu C., Tong M.Q. Comparative proteome analysis of neural retinas from type 2 diabetic rats by two-dimensional electrophoresis. Curr. Eye Res. 2007, 32:891-901.
    • (2007) Curr. Eye Res. , vol.32 , pp. 891-901
    • Wang, Y.D.1    Wu, J.D.2    Jiang, Z.L.3    Wang, Y.B.4    Wang, X.H.5    Liu, C.6    Tong, M.Q.7
  • 151
    • 77957146772 scopus 로고    scopus 로고
    • Alpha-crystallin promotes rat retinal neurite growth on myelin substrates in vitro
    • Wang Y.H., Wang D.W., Wu N., Wang Y., Yin Z.Q. Alpha-crystallin promotes rat retinal neurite growth on myelin substrates in vitro. Ophthalmic Res. 2011, 45:164-168.
    • (2011) Ophthalmic Res. , vol.45 , pp. 164-168
    • Wang, Y.H.1    Wang, D.W.2    Wu, N.3    Wang, Y.4    Yin, Z.Q.5
  • 152
    • 84858861920 scopus 로고    scopus 로고
    • Alpha-Crystallin promotes rat axonal regeneration through regulation of RhoA/rock/cofilin/MLC signaling pathways
    • Wang Y.H., Wang D.W., Wu N., Wang Y., Yin Z.Q. alpha-Crystallin promotes rat axonal regeneration through regulation of RhoA/rock/cofilin/MLC signaling pathways. J. Mol. Neurosci. 2012, 46:138-144.
    • (2012) J. Mol. Neurosci. , vol.46 , pp. 138-144
    • Wang, Y.H.1    Wang, D.W.2    Wu, N.3    Wang, Y.4    Yin, Z.Q.5
  • 154
    • 0023942820 scopus 로고
    • Regeneration of adult rat retinal ganglion cell processes in monolayer culture: comparisons between cultures of adult and neonatal neurons
    • Wigley C.B., Berry M. Regeneration of adult rat retinal ganglion cell processes in monolayer culture: comparisons between cultures of adult and neonatal neurons. Brain Res. 1988, 470:85-98.
    • (1988) Brain Res. , vol.470 , pp. 85-98
    • Wigley, C.B.1    Berry, M.2
  • 155
    • 0025117557 scopus 로고
    • Evolution of a protein superfamily: relationships between vertebrate lens crystallins and microorganism dormancy proteins
    • Wistow G. Evolution of a protein superfamily: relationships between vertebrate lens crystallins and microorganism dormancy proteins. J. Mol. Evol. 1990, 30:140-145.
    • (1990) J. Mol. Evol. , vol.30 , pp. 140-145
    • Wistow, G.1
  • 156
    • 0023917935 scopus 로고
    • Lens crystallins: the evolution and expression of proteins for a highly specialized tissue
    • Wistow G.J., Piatigorsky J. Lens crystallins: the evolution and expression of proteins for a highly specialized tissue. Annu. Rev. Biochem 1988, 57:479-504.
    • (1988) Annu. Rev. Biochem , vol.57 , pp. 479-504
    • Wistow, G.J.1    Piatigorsky, J.2
  • 157
    • 33745451432 scopus 로고    scopus 로고
    • Lens epithelial cells promote regrowth of retinal ganglion cells in culture and in vivo
    • Wong W.K., Cheung A.W., Cho E.Y. Lens epithelial cells promote regrowth of retinal ganglion cells in culture and in vivo. Neuroreport 2006, 17:699-704.
    • (2006) Neuroreport , vol.17 , pp. 699-704
    • Wong, W.K.1    Cheung, A.W.2    Cho, E.Y.3
  • 158
    • 39149145829 scopus 로고    scopus 로고
    • Exacerbation of retinal degeneration in the absence of alpha crystallins in an in vivo model of chemically induced hypoxia
    • Yaung J., Kannan R., Wawrousek E.F., Spee C., Sreekumar P.G., Hinton D.R. Exacerbation of retinal degeneration in the absence of alpha crystallins in an in vivo model of chemically induced hypoxia. Exp. Eye Res. 2008, 86:355-365.
    • (2008) Exp. Eye Res. , vol.86 , pp. 355-365
    • Yaung, J.1    Kannan, R.2    Wawrousek, E.F.3    Spee, C.4    Sreekumar, P.G.5    Hinton, D.R.6
  • 162
    • 51649098097 scopus 로고    scopus 로고
    • Alpha-crystallin protected axons from optic nerve degeneration after crushing in rats
    • Ying X., Zhang J., Wang Y., Wu N., Wang Y., Yew D.T. Alpha-crystallin protected axons from optic nerve degeneration after crushing in rats. J. Mol. Neurosci. 2008, 35:253-258.
    • (2008) J. Mol. Neurosci. , vol.35 , pp. 253-258
    • Ying, X.1    Zhang, J.2    Wang, Y.3    Wu, N.4    Wang, Y.5    Yew, D.T.6
  • 163
    • 0242416955 scopus 로고    scopus 로고
    • Differential temporal and spatial expression of immediate early genes in retinal neurons after ischemia-reperfusion injury
    • Yoshimura N., Kikuchi T., Kuroiwa S., Gaun S. Differential temporal and spatial expression of immediate early genes in retinal neurons after ischemia-reperfusion injury. Invest. Ophthalmol. Vis. Sci. 2003, 44:2211-2220.
    • (2003) Invest. Ophthalmol. Vis. Sci. , vol.44 , pp. 2211-2220
    • Yoshimura, N.1    Kikuchi, T.2    Kuroiwa, S.3    Gaun, S.4


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