Reduction of experimental diabetic vascular leakage and pericyte apoptosis in mice by delivery of αa-crystallin with a recombinant adenovirus

Diabetologia

Volumn 55, Issue 10, 2012, Pages 2835-2844

  Kim, Y H ^a   Park, S Y ^a   Park, J ^a   Kim, Y S ^a   Hwang, E M ^b   Park, J Y ^c   Roh, G S ^a   Kim, H J ^a   Kang, S S ^a   Cho, G J ^a   Choi, W S ^a  

^a Gyeongsang National University   (South Korea)

^b Korea Institute of Science and Technology   (South Korea)

^c Gyeongsang National University School of Medicine   (South Korea)

Author keywords

A Crystallin; BRB breakdown; Diabetic retinopathy; Pericyte loss

Indexed keywords

ADENOVIRUS VECTOR; ALPHA CRYSTALLIN; PROTEOCHONDROITIN SULFATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; ASSAY; CELL COUNT; CELL LOSS; CONTROLLED STUDY; DIABETIC ANGIOPATHY; DIABETIC RETINOPATHY; DIABETIC VASCULAR LEAKAGE; DRUG EFFICACY; FLUORESCENCE ANGIOGRAPHY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; LEUKOCYTE ADHERENCE; MALE; MOUSE; NONHUMAN; PERICYTE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STREPTOZOCIN DIABETES; TWO DIMENSIONAL ELECTROPHORESIS; VIRAL GENE DELIVERY SYSTEM;

ADENOVIRIDAE; ALPHA-CRYSTALLIN A CHAIN; ANIMALS; APOPTOSIS; CELLS, CULTURED; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC RETINOPATHY; DISEASE MODELS, ANIMAL; DRUG DELIVERY SYSTEMS; GLUCOSE; INTRAVITREAL INJECTIONS; MALE; MICE; MICE, INBRED C57BL; PERICYTES; STREPTOZOCIN; TREATMENT OUTCOME;

EID: 84866083771     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-012-2625-y     Document Type: Article

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