-
1
-
-
33749440219
-
Age-related macular degeneration
-
de Jong PT (2006) Age-related macular degeneration. N Engl J Med 355: 1474-1485.
-
(2006)
N Engl J Med
, vol.355
, pp. 1474-1485
-
-
de Jong, P.T.1
-
2
-
-
0038708118
-
Age-related macular degeneration: Etiology, pathogenesis, and therapeutic strategies
-
Ambati J, Ambati BK, Yoo SH, Lanchulev S, Adamis AP (2003) Age-related macular degeneration: etiology, pathogenesis, and therapeutic strategies. Surv Ophthalmol 48: 257-293.
-
(2003)
Surv Ophthalmol
, vol.48
, pp. 257-293
-
-
Ambati, J.1
Ambati, B.K.2
Yoo, S.H.3
Lanchulev, S.4
Adamis, A.P.5
-
3
-
-
0014824604
-
The interphotoreceptor matrix: Electron microscopic and histochemical observations on the vertebrate retina
-
Röhlich P (1970) The interphotoreceptor matrix: electron microscopic and histochemical observations on the vertebrate retina. Exp Eye Res 10: 80-86.
-
(1970)
Exp Eye Res
, vol.10
, pp. 80-86
-
-
Röhlich, P.1
-
4
-
-
0024805462
-
Selective presence of acid hydrolases in the interphotoreceptor matrix
-
Adler AJ (1989) Selective presence of acid hydrolases in the interphotoreceptor matrix. Exp Eye Res 49: 1067-1077.
-
(1989)
Exp Eye Res
, vol.49
, pp. 1067-1077
-
-
Adler, A.J.1
-
5
-
-
1842478123
-
Current concepts in the pathogenesis of age-related macular degeneration
-
Zarbin MA (2004) Current concepts in the pathogenesis of age-related macular degeneration. Arch Ophthalmol 122: 598-614.
-
(2004)
Arch Ophthalmol
, vol.122
, pp. 598-614
-
-
Zarbin, M.A.1
-
7
-
-
0026584271
-
Protein folding in the cell
-
Gething MJ, Sambrook J (1992) Protein folding in the cell. Nature 355: 33-45.
-
(1992)
Nature
, vol.355
, pp. 33-45
-
-
Gething, M.J.1
Sambrook, J.2
-
8
-
-
33845913216
-
Intracellular and extracellular functions of heat shock proteins: Repercussions in cancer therapy
-
Schmitt E, Gehrmann M, Brunet M, Multhoff G, Garrido C (2007) Intracellular and extracellular functions of heat shock proteins: repercussions in cancer therapy. J Leukoc Biol 81: 15-27.
-
(2007)
J Leukoc Biol
, vol.81
, pp. 15-27
-
-
Schmitt, E.1
Gehrmann, M.2
Brunet, M.3
Multhoff, G.4
Garrido, C.5
-
9
-
-
0038701886
-
The mystery of nonclassical protein secretion. A current view on cargo proteins and potential export routes
-
Nickel W (2003) The mystery of nonclassical protein secretion. A current view on cargo proteins and potential export routes. Eur J Biochem 270: 2109-2119.
-
(2003)
Eur J Biochem
, vol.270
, pp. 2109-2119
-
-
Nickel, W.1
-
10
-
-
0026483279
-
Alpha-crystallin can function as a molecular chaperone
-
Horwitz J (1992) Alpha-crystallin can function as a molecular chaperone. Proc Natl Acad Sci USA 89: 10449-10453.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 10449-10453
-
-
Horwitz, J.1
-
11
-
-
0035844174
-
The small heat shock protein alpha Bcrystallin negatively regulates cytochrome c- and caspase-8-dependent activation of caspase-3 by inhibiting its autoproteolytic maturation
-
Kamradt MC, Chen F, Cryns VL (2001) The small heat shock protein alpha Bcrystallin negatively regulates cytochrome c- and caspase-8-dependent activation of caspase-3 by inhibiting its autoproteolytic maturation. J Biol Chem 276: 16059-16063.
-
(2001)
J Biol Chem
, vol.276
, pp. 16059-16063
-
-
Kamradt, M.C.1
Chen, F.2
Cryns, V.L.3
-
12
-
-
34147145520
-
Alpha-Crystallin distribution in retinal pigment epithelium and effect of gene knockouts on sensitivity to oxidative stress
-
Yaung J, Jin M, Barron E, Spee C, Wawrousek EF, et al. (2007) Alpha-Crystallin distribution in retinal pigment epithelium and effect of gene knockouts on sensitivity to oxidative stress. Mol Vis 13: 566-577.
-
(2007)
Mol Vis
, vol.13
, pp. 566-577
-
-
Yaung, J.1
Jin, M.2
Barron, E.3
Spee, C.4
Wawrousek, E.F.5
-
13
-
-
38149099098
-
Localization of phosphorylated alphaB-crystallin to heart mitochondria during ischemia-reperfusion
-
Jin JK, Whittaker R, Glassy MS, Barlow SB, Gottlieb RA, et al. (2008) Localization of phosphorylated alphaB-crystallin to heart mitochondria during ischemia-reperfusion. Am J Physiol Heart Circ Physiol 294: H337-H344.
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.294
-
-
Jin, J.K.1
Whittaker, R.2
Glassy, M.S.3
Barlow, S.B.4
Gottlieb, R.A.5
-
14
-
-
39149145829
-
Exacerbation of retinal degeneration in the absence of alpha crystallins in an in vivo model of chemically induced hypoxia
-
Yaung J, Kannan R, Wawrousek EF, Spee C, Sreekumar PG, et al. (2008) Exacerbation of retinal degeneration in the absence of alpha crystallins in an in vivo model of chemically induced hypoxia. Exp Eye Res 86: 355-365.
-
(2008)
Exp Eye Res
, vol.86
, pp. 355-365
-
-
Yaung, J.1
Kannan, R.2
Wawrousek, E.F.3
Spee, C.4
Sreekumar, P.G.5
-
15
-
-
34248553886
-
Human retinal pigment epithelium cell changes and expression of alphaB-crystallin: A biomarker for retinal pigment epithelium cell change in age-related macular degeneration
-
De S, Rabin DM, Salero E, Lederman PL, Temple S, et al. (2007) Human retinal pigment epithelium cell changes and expression of alphaB-crystallin: a biomarker for retinal pigment epithelium cell change in age-related macular degeneration. Arch Ophthalmol 125: 641-645.
-
(2007)
Arch Ophthalmol
, vol.125
, pp. 641-645
-
-
De, S.1
Rabin, D.M.2
Salero, E.3
Lederman, P.L.4
Temple, S.5
-
16
-
-
33748749534
-
Retinoschisin forms a mutlimolecular matrix and cytoplasmic proteins: Interactions with beta2 laminin and alphaB-crystallin
-
Steiner-Champliaud MF, Sahel J, Hicks D (2006) Retinoschisin forms a mutlimolecular matrix and cytoplasmic proteins: interactions with beta2 laminin and alphaB-crystallin. Mol Vis 12: 892-901.
-
(2006)
Mol Vis
, vol.12
, pp. 892-901
-
-
Steiner-Champliaud, M.F.1
Sahel, J.2
Hicks, D.3
-
17
-
-
25844496962
-
Proteomic analysis of the porcine interphotoreceptor matrix
-
Hauck SM, Schoeffmann S, Deeg CA, Gloeckner CJ, Swiatek-de Lange M, et al. (2005) Proteomic analysis of the porcine interphotoreceptor matrix. Proteomics 5: 3623-3636.
-
(2005)
Proteomics
, vol.5
, pp. 3623-3636
-
-
Hauck, S.M.1
Schoeffmann, S.2
Deeg, C.A.3
Gloeckner, C.J.4
de Swiatek-Lange, M.5
-
18
-
-
67649402326
-
A protocol for the culture and differentiation of highly polarized human retinal pigment epithelial cells
-
Sonoda S, Spee C, Barron E, Ryan SJ, Kannan R, et al. (2009) A protocol for the culture and differentiation of highly polarized human retinal pigment epithelial cells. Nat Protoc 4: 662-673.
-
(2009)
Nat Protoc
, vol.4
, pp. 662-673
-
-
Sonoda, S.1
Spee, C.2
Barron, E.3
Ryan, S.J.4
Kannan, R.5
-
19
-
-
77953434480
-
Attainment of polarity promotes growth factor secretion by retinal pigment epithelial cells: Relevance to age-related macular degeneration
-
Sonoda S, Sreekumar PG, Kase S, Spee C, Ryan SJ, et al. (2010) Attainment of polarity promotes growth factor secretion by retinal pigment epithelial cells: relevance to age-related macular degeneration. Aging 2: 28-42.
-
(2010)
Aging
, vol.2
, pp. 28-42
-
-
Sonoda, S.1
Sreekumar, P.G.2
Kase, S.3
Spee, C.4
Ryan, S.J.5
-
20
-
-
41949130800
-
N-(4- hydroxyphenyl) retinamide augments laser-induced choroidal neovascularization in mice
-
Sreekumar PG, Zhou J, Sohn J, Spee C, Ryan SJ, et al. (2008) N-(4- hydroxyphenyl) retinamide augments laser-induced choroidal neovascularization in mice. Invest Ophthalmol Vis Sci 49: 1210-1220.
-
(2008)
Invest Ophthalmol Vis Sci
, vol.49
, pp. 1210-1220
-
-
Sreekumar, P.G.1
Zhou, J.2
Sohn, J.3
Spee, C.4
Ryan, S.J.5
-
21
-
-
20744436655
-
Exosome-dependent trafficking of HSP70: A novel secretory pathway for cellular stress proteins
-
Lancaster GI, Febbraio MA (2005) Exosome-dependent trafficking of HSP70: a novel secretory pathway for cellular stress proteins. J Biol Chem 280: 23349-23355.
-
(2005)
J Biol Chem
, vol.280
, pp. 23349-23355
-
-
Lancaster, G.I.1
Febbraio, M.A.2
-
22
-
-
0037484291
-
Expression of the molecular chaperone Hsp70 in detergent-resistant microdomains correlates with its membrane delivery and release
-
Broquet AH, Thomas G, Masliah J, Trugnan G, Bachelet M (2003) Expression of the molecular chaperone Hsp70 in detergent-resistant microdomains correlates with its membrane delivery and release. J Biol Chem 278: 21601-21616.
-
(2003)
J Biol Chem
, vol.278
, pp. 21601-21616
-
-
Broquet, A.H.1
Thomas, G.2
Masliah, J.3
Trugnan, G.4
Bachelet, M.5
-
23
-
-
43249109372
-
Isolation and characterization of exosomes from cell culture supernatants and biological fluids
-
Unit 322
-
Théry C, Amigorena S, Raposo G, Clayton A (2006) Isolation and characterization of exosomes from cell culture supernatants and biological fluids. Curr Protoc Cell Biol Chapter 3: Unit 3.22.
-
(2006)
Curr Protoc Cell Biol Chapter
, vol.3
-
-
Théry, C.1
Amigorena, S.2
Raposo, G.3
Clayton, A.4
-
24
-
-
34447525068
-
HSP60 trafficking in adult cardiac myocytes: Role of the exosomal pathway
-
Gupta S, Knowlton AA (2007) HSP60 trafficking in adult cardiac myocytes: role of the exosomal pathway. Am J Physiol Heart Circ Physiol 292: H3052-3056.
-
(2007)
Am J Physiol Heart Circ Physiol
, vol.292
-
-
Gupta, S.1
Knowlton, A.A.2
-
25
-
-
58349109733
-
Autophagy and exosomes in the aged retinal pigment epithelium: Possible relevance to drusen formation and age-related macular degeneration
-
Wang AL, Lukas TJ, Yuan M, Du N, Tso MO, et al. (2009) Autophagy and exosomes in the aged retinal pigment epithelium: possible relevance to drusen formation and age-related macular degeneration. PLoS One 4: e4160.
-
(2009)
PLoS One
, vol.4
-
-
Wang, A.L.1
Lukas, T.J.2
Yuan, M.3
Du, N.4
Tso, M.O.5
-
26
-
-
0032503968
-
Hsp104, Hsp70, and Hsp40: A novel chaperone system that rescues previously aggregated proteins
-
Glover JR, Lindquist S (1998) Hsp104, Hsp70, and Hsp40: a novel chaperone system that rescues previously aggregated proteins. Cell 94: 73-82.
-
(1998)
Cell
, vol.94
, pp. 73-82
-
-
Glover, J.R.1
Lindquist, S.2
-
28
-
-
71049145998
-
Proteomics characterization of cell membrane blebs in human retinal pigment epithelium cells
-
Alcazar O, Hawkridge AM, Collier TS, Cousins SW, Bhattacharya SK, et al. (2009) Proteomics characterization of cell membrane blebs in human retinal pigment epithelium cells. Mol Cell Proteomics 8: 2201-2211.
-
(2009)
Mol Cell Proteomics
, vol.8
, pp. 2201-2211
-
-
Alcazar, O.1
Hawkridge, A.M.2
Collier, T.S.3
Cousins, S.W.4
Bhattacharya, S.K.5
-
29
-
-
0024541931
-
Selective release from cultured mammalian cells of heat-shock (stress) proteins that resemble glia-axon transfer proteins
-
Hightower LE, Guidon PT Jr (1989) Selective release from cultured mammalian cells of heat-shock (stress) proteins that resemble glia-axon transfer proteins. J Cell Physiol 138: 257-266.
-
(1989)
J Cell Physiol
, vol.138
, pp. 257-266
-
-
Hightower, L.E.1
Guidon Jr., P.T.2
-
30
-
-
0026548976
-
Basic fibroblast growth factor, a protein devoid of secretory signal sequence, is released by cells via a pathway independent of the endoplasmic reticulum-Golgi complex
-
Mignati P, Morimoto T, Rifkin DB (1992) Basic fibroblast growth factor, a protein devoid of secretory signal sequence, is released by cells via a pathway independent of the endoplasmic reticulum-Golgi complex. J Cell Physiol 151: 81-93.
-
(1992)
J Cell Physiol
, vol.151
, pp. 81-93
-
-
Mignati, P.1
Morimoto, T.2
Rifkin, D.B.3
-
31
-
-
0345599951
-
Lipid raftassociated protein sorting in exosomes
-
de Gassart A, Geminard C, Fevrier B, Raposo G, Vidal M (2003) Lipid raftassociated protein sorting in exosomes. Blood 102: 4336-4344.
-
(2003)
Blood
, vol.102
, pp. 4336-4344
-
-
de Gassart, A.1
Geminard, C.2
Fevrier, B.3
Raposo, G.4
Vidal, M.5
-
32
-
-
42149127827
-
AlphaBcrystallin protects retinal tissue during Staphylococcus aureus-induced endophthalmitis
-
Whiston EA, Sugi N, Kamradt MC, Sack C, Heimer SR, et al. (2008) AlphaBcrystallin protects retinal tissue during Staphylococcus aureus-induced endophthalmitis. Infect Immun 76: 1781-1790.
-
(2008)
Infect Immun
, vol.76
, pp. 1781-1790
-
-
Whiston, E.A.1
Sugi, N.2
Kamradt, M.C.3
Sack, C.4
Heimer, S.R.5
-
33
-
-
34547152612
-
Protective and therapeutic role for alphaB-crystallin in autoimmune demyelination
-
Ousman SS, Tomooka BH, van Noort JM, Wawrousek EF, O'Connor KC, et al. (2007) Protective and therapeutic role for alphaB-crystallin in autoimmune demyelination. Nature 448: 474-479.
-
(2007)
Nature
, vol.448
, pp. 474-479
-
-
Ousman, S.S.1
Tomooka, B.H.2
van Noort, J.M.3
Wawrousek, E.F.4
O'Connor, K.C.5
-
34
-
-
33845655395
-
Recruitment of phosphorylated small heat shock protein Hsp27 to nuclear speckles without stress
-
Bryantsev AL, Chechenova MB, Shelden EA (2007) Recruitment of phosphorylated small heat shock protein Hsp27 to nuclear speckles without stress. Exp Cell Res 313: 195-209.
-
(2007)
Exp Cell Res
, vol.313
, pp. 195-209
-
-
Bryantsev, A.L.1
Chechenova, M.B.2
Shelden, E.A.3
-
35
-
-
2442681777
-
Human alphaA- and alphaBcrystallins bind to Bax and Bcl-X(S) to sequester their translocation during staurosporine-induced apoptosis
-
Mao YW, Liu JP, Xiang H, Li DW (2004) Human alphaA- and alphaBcrystallins bind to Bax and Bcl-X(S) to sequester their translocation during staurosporine-induced apoptosis. Cell Death Differ 11: 512-526.
-
(2004)
Cell Death Differ
, vol.11
, pp. 512-526
-
-
Mao, Y.W.1
Liu, J.P.2
Xiang, H.3
Li, D.W.4
-
36
-
-
77950860248
-
Characterizing molecular diffusion in the lens capsule
-
Danysh BP, Patel TP, Czymmek KJ, Edwards DA, Wang L, Pande J, et al. (2010) Characterizing molecular diffusion in the lens capsule. Matrix Biol 29: 228-236.
-
(2010)
Matrix Biol
, vol.29
, pp. 228-236
-
-
Danysh, B.P.1
Patel, T.P.2
Czymmek, K.J.3
Edwards, D.A.4
Wang, L.5
Pande, J.6
-
37
-
-
0347664084
-
Localization of pigment epithelium derived factor (PEDF) in developing and adult human ocular tissues
-
Karakousis PC, John SK, Behling KC, Surace EM, Smith JE, et al. (2001) Localization of pigment epithelium derived factor (PEDF) in developing and adult human ocular tissues. Mol Vis 7: 154-163.
-
(2001)
Mol Vis
, vol.7
, pp. 154-163
-
-
Karakousis, P.C.1
John, S.K.2
Behling, K.C.3
Surace, E.M.4
Smith, J.E.5
-
38
-
-
0043132253
-
Nuclear staining for the small heat shock protein alphaB-crystallin colocalizes with splicing factor SC35
-
van Rijk AE, Stege GJ, Bennink EJ, May A, Bloemendal H (2003) Nuclear staining for the small heat shock protein alphaB-crystallin colocalizes with splicing factor SC35. Eur J Cell Biol 82: 361-368.
-
(2003)
Eur J Cell Biol
, vol.82
, pp. 361-368
-
-
van Rijk, A.E.1
Stege, G.J.2
Bennink, E.J.3
May, A.4
Bloemendal, H.5
-
39
-
-
11144258543
-
Drusen proteome analysis: An approach to the etiology of age-related macular degeneration
-
Crabb JW, Miyagi M, Gu X, Shadrach K, West KA, et al. (2002) Drusen proteome analysis: an approach to the etiology of age-related macular degeneration. Proc Natl Acad Sci USA 99: 14682-14687.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 14682-14687
-
-
Crabb, J.W.1
Miyagi, M.2
Gu, X.3
Shadrach, K.4
West, K.A.5
-
40
-
-
20444390503
-
Crystallin distribution in Bruch's membrane-choroid complex from AMD and age-matched donor eyes
-
Nakata K, Crabb JW, Hollyfield JG (2005) Crystallin distribution in Bruch's membrane-choroid complex from AMD and age-matched donor eyes. Exp Eye Res 80: 821-826.
-
(2005)
Exp Eye Res
, vol.80
, pp. 821-826
-
-
Nakata, K.1
Crabb, J.W.2
Hollyfield, J.G.3
-
41
-
-
0037285481
-
Intense light exposure changes the crystallin content in retina
-
Sakaguchi H, Miyagi M, Darrow RM, Crabb JS, Hollyfield JG, et al. (2003) Intense light exposure changes the crystallin content in retina. Exp Eye Res 76: 131-133.
-
(2003)
Exp Eye Res
, vol.76
, pp. 131-133
-
-
Sakaguchi, H.1
Miyagi, M.2
Darrow, R.M.3
Crabb, J.S.4
Hollyfield, J.G.5
-
42
-
-
33644799775
-
Synaptic pathology, altered gene expression, and degeneration in photoreceptors impacted by drusen
-
Johnson PT, Brown MN, Pulliam BC, Anderson DH, Johnson LV. Synaptic pathology, altered gene expression, and degeneration in photoreceptors impacted by drusen (2005). Invest Ophthalmol Vis Sci 46: 4788-4795.
-
(2005)
Invest Ophthalmol Vis Sci
, vol.46
, pp. 4788-4795
-
-
Johnson, P.T.1
Brown, M.N.2
Pulliam, B.C.3
Anderson, D.H.4
Johnson, L.V.5
-
43
-
-
33745650321
-
The proteome of central and peripheral retina with progression of age-related macular degeneration
-
Ethen CM, Reilly C, Feng X, Olsen TW, Ferrington DA (2006) The proteome of central and peripheral retina with progression of age-related macular degeneration. Invest Ophthalmol Vis Sci 47: 2280-2290.
-
(2006)
Invest Ophthalmol Vis Sci
, vol.47
, pp. 2280-2290
-
-
Ethen, C.M.1
Reilly, C.2
Feng, X.3
Olsen, T.W.4
Ferrington, D.A.5
-
44
-
-
62749181868
-
Transfer of microRNAs by embryonic stem cell microvesicles
-
Yuan A, Farber EL, Rapoport AL, Tejada D, Deniskin R, et al. (2009) Transfer of microRNAs by embryonic stem cell microvesicles. PLoS One 4: e4722.
-
(2009)
PLoS One
, vol.4
-
-
Yuan, A.1
Farber, E.L.2
Rapoport, A.L.3
Tejada, D.4
Deniskin, R.5
|