Functional rescue of experimental ischemic optic neuropathy with αb-crystallin

Eye

Volumn 25, Issue 6, 2011, Pages 809-817

  Pangratz Fuehrer, S ^a   Kaur, K ^a   Ousman, S S ^a   Steinman, L ^a   Liao, Y J ^a,b  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b STANFORD UNIVERSITY   (United States)

Author keywords

aB crystallin; anterior ischemic optic neuropathy; heat shock protein; retinal ganglion cell; visual evoked potential

Indexed keywords

ALPHA CRYSTALLIN;

AMPLITUDE MODULATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CELL ACTIVATION; CELL SURVIVAL; CONTROLLED STUDY; EVOKED VISUAL RESPONSE; INFLAMMATION; ISCHEMIC OPTIC NEUROPATHY; LATENT PERIOD; MICROGLIA; MOUSE; MYELINATION; NONHUMAN; OLIGODENDROGLIA; OPTIC NERVE; RETINA GANGLION CELL; TREATMENT DURATION; TREATMENT OUTCOME; UPREGULATION;

EID: 79958761661     PISSN: 0950222X     EISSN: 14765454     Source Type: Journal    
DOI: 10.1038/eye.2011.42     Document Type: Article

References (42)

1. Arnold AC. Pathogenesis of nonarteritic anterior ischemic optic neuropathy. J Neuroophthalmol 2003;23(2):157-163. (Pubitemid 36676943)
2. Hayreh SS. Ischemic optic neuropathy. Prog Retin Eye Res 2009;28(1):34-62.
3. Potarazu SV. Ischemic optic neuropathy: models for mechanism of disease. Clin Neurosci 1997;4(5):264-269. (Pubitemid 27382880)
4. Levin LA, Danesh-Meyer HV. Hypothesis: a venous etiology for nonarteritic anterior ischemic optic neuropathy. Arch Ophthalmol 2008;126(11):1582-1585.
5. Bernstein SL, Guo Y, Kelman SE, Flower RW, Johnson MA. Functional and cellular responses in a novel rodent model of anterior ischemic optic neuropathy. Invest Ophthalmol Vis Sci 2003;44(10):4153-4162. (Pubitemid 37186246)
6. Chen CS, Johnson MA, Flower RA, Slater BJ, Miller NR, Bernstein SL. A primate model of nonarteritic anterior ischemic optic neuropathy. Invest Ophthalmol Vis Sci 2008;49(7):2985-2992.
7. Slater BJ, Mehrabian Z, Guo Y, Hunter A, Bernstein SL. Rodent anterior ischemic optic neuropathy (rAION) induces regional retinal ganglion cell apoptosis with a unique temporal pattern. Invest Ophthalmol Vis Sci 2008;49(8):3671-3676.
8. Goldenberg-Cohen N, Guo Y, Margolis F, Cohen Y, Miller NR, Bernstein SL. Oligodendrocyte dysfunction after induction of experimental anterior optic nerve ischemia. Invest Ophthalmol Vis Sci 2005;46(8):2716-2725. (Pubitemid 43086691)
9. Danylkova NO, Alcala SR, Pomeranz HD, McLoon LK. Neuroprotective effects of brimonidine treatment in a rodent model of ischemic optic neuropathy. Exp Eye Res 2007;84(2):293-301. (Pubitemid 44958470)
10. Bernstein SL, Guo Y, Slater BJ, Puche A, Kelman SE. Neuron stress and loss following rodent anterior ischemic optic neuropathy in double-reporter transgenic mice. Invest Ophthalmol Vis Sci 2007;48(5):2304-2310. (Pubitemid 351261310)
11. Danylkova NO, Pomeranz HD, Alcala SR, McLoon LK. Histological and morphometric evaluation of transient retinal and optic nerve ischemia in rat. Brain Res 2006;1096:20-29. (Pubitemid 44202453)
12. Munemasa Y, Kwong JM, Caprioli J, Piri N. The role of alphaA-and alphas in the survival of retinal ganglion cells after optic nerve axotomy. Invest Ophthalmol Vis Sci 2009;50(8):3869-3875.
13. Slavotinek AM, Biesecker LG. Unfolding the role of chaperones and chaperonins in human disease. Trends Genet 2001;17(9):528-535. (Pubitemid 32763051)
14. Andley UP. Crystallins in the eye: Function and pathology. Prog Retin Eye Res 2007;26(1):78-98. (Pubitemid 44894995)
15. Ousman SS, Tomooka BH, van Noort JM, Wawrousek EF, O'onnor KC, Hafler DA et al. Protective and therapeutic role for alphaB-crystallin in autoimmune demyelination. Nature 2007;448(7152):474-479. (Pubitemid 47123511)
16. Oertel MF, May CA, Bloemendal H, Lutjen-Drecoll E. Alpha-B-crystallin expression in tissues derived from different species in different age groups. Ophthalmologica 2000;214(1):13-23. (Pubitemid 30084877)
17. Bernstein SL, Koo JH, Slater BJ, Guo Y, Margolis FL. Analysis of optic nerve stroke by retinal Bex expression. Mol Vis 2006;12:147-155.
18. Jain A, Blumenkranz MS, Paulus Y, Wiltberger MW, Andersen DE, Huie P et al. Effect of pulse duration on size and character of the lesion in retinal photocoagulation. Arch Ophthalmol 2008;126(1):78-85.
19. Porciatti V, Pizzorusso T, Maffei L. The visual physiology of the wild type mouse determined with pattern VEPs. Vision Res 1999;39(18):3071-3081. (Pubitemid 29251241)
20. Ridder III WH, Nusinowitz S. The visual evoked potential in the mouse-origins and response characteristics. Vision Res 2006;46(6-7):902-913. (Pubitemid 43016120)
21. Whiston EA, Sugi N, Kamradt MC, Heimer SR, Engelbert M, Wawrousek EF et al. alphaB-crystallin protects retinal tissue during Staphylococcus aureus-induced endophthalmitis. Infect Immun 2008;76(4):1781-1790. (Pubitemid 351562024)
22. Humphrey MF, Moore SR. Microglial responses to focal lesions of the rabbit retina: correlation with neural and macroglial reactions. Glia 1996;16(4):325-341. (Pubitemid 26344158)
23. Zhang C, Guo Y, Miller NR, Bernstein SL. Optic nerve infarction and post-ischemic inflammation in the rodent model of anterior ischemic optic neuropathy (rAION). Brain Res 2009;1264:67-75.
24. Watson BD, Dietrich WD, Busto R, Wachtel MS, Ginsberg MD. Induction of reproducible brain infarction by photochemically initiated thrombosis. Ann Neurol 1985;17(5):497-504. (Pubitemid 15019990)
25. Janaky M, Fulop Z, Palffy A, Benedek K, Benedek G. Electrophysiological findings in patients with nonarteritic anterior ischemic optic neuropathy. Clin Neurophysiol 2006;117(5):1158-1166.
26. Tormene AP, Doro D, Mantovani E, Fabris S, Moro F. Electrophysiological findings in anterior ischemic optic neuropathy. Metab Pediatr Syst Ophthalmol 1989;12(1-3):76-79. (Pubitemid 19133565)
27. Furuyoshi N, Furuyoshi M, May CA, Hayreh SS, Alm A, Lutjen-Drecoll E. Vascular and glial changes in the retrolaminar optic nerve in glaucomatous monkey eyes. Ophthalmologica 2000;214(1):24-32. (Pubitemid 30084878)
28. Sakaguchi H, Miyagi M, Darrow RM, Crabb JS, Hollyfield JG, Organisciak DT et al. Intense light exposure changes the crystallin content in retina. Exp Eye Res 2003;76(1):131-133. (Pubitemid 36268723)
29. Vazquez-Chona FR, Lu L, Williams RW, Geisert EE. Genomic loci modulating the retinal transcriptome in wound healing. Gene Regul Syst Bio 2007;1:327-348.
30. Yoshimura N, Kikuchi T, Kuroiwa S, Gaun S. Differential temporal and spatial expression of immediate early genes in retinal neurons after ischemia-reperfusion injury. Invest Ophthalmol Vis Sci 2003;44(5):2211-2220. (Pubitemid 36520319)
31. Ahmed F, Torrado M, Zinovieva RD, Senatorov VV, Wistow G, Tomarev SI. Gene expression profile of the rat eye iridocorneal angle: NEIBank expressed sequence tag analysis. Invest Ophthalmol Vis Sci 2004;45(9):3081-3090. (Pubitemid 39121839)
32. Piri N, Song M, Kwong JM, Caprioli J. Modulation of alpha and beta crystallin expression in rat retinas with ocular hypertension-induced ganglion cell degeneration. Brain Res 2007;1141:1-9. (Pubitemid 46365636)
33. Steele MR, Inman DM, Calkins DJ, Horner PJ, Vetter ML. Microarray analysis of retinal gene expression in the DBA/2J model of glaucoma. Invest Ophthalmol Vis Sci 2006;47(3):977-985. (Pubitemid 46768330)
34. Xi J, Farjo R, Yoshida S, Kern TS, Swaroop A, Andley UP. A comprehensive analysis of the expression of crystallins in mouse retina. Mol Vis 2003;9:410-419. (Pubitemid 38104819)
35. Yu AL, Fuchshofer R, Birke M, Priglinger SG, Eibl KH, Kampik A et al. Hypoxia/reoxygenation and TGF-beta increase alphaB-crystallin expression in human optic nerve head astrocytes. Exp Eye Res 2007;84(4):694-706. (Pubitemid 46400636)
36. Tamm ER, Russell P, Johnson DH, Piatigorsky J. Human and monkey trabecular meshwork accumulate alpha B-crystallin in response to heat shock and oxidative stress. Invest Ophthalmol Vis Sci 1996;37(12):2402-2413. (Pubitemid 26391278)
37. Yaung J, Jin M, Barron E, Spee C, Wawrousek EF, Kannan R et al. alpha-Crystallin distribution in retinal pigment epithelium and effect of gene knockouts on sensitivity to oxidative stress. Mol Vis 2007;13:566-577.
38. Alge CS, Priglinger SG, Neubauer AS, Kampik A, Zillig M, Bloemendal H et al. Retinal pigment epithelium is protected against apoptosis by alphaB-crystallin. Invest Ophthalmol Vis Sci 2002;43(11):3575-3582. (Pubitemid 35334367)
39. Saraswathy S, Nguyen AM, Rao NA. The Role of TLR4 in Photoreceptor {alpha}A crystallin upregulation during early EAU. Invest Ophthalmol Vis Sci 2010;51(7):3680-3686.
40. Heiduschka P, Schraermeyer U. Comparison of visual function in pigmented and albino rats by electroretinography and visual evoked potentials. Graefes Arch Clin Exp Ophthalmol 2008;246(11):1559-1573.
41. Sun W, Li N, He S. Large-scale morphological survey of mouse retinal ganglion cells. J Comp Neurol 2002;451(2):115-126. (Pubitemid 34920404)
42. Ying X, Zhang J, Wang Y, Wu N, Yew DT. Alpha-crystallin protected axons from optic nerve degeneration after crushing in rats. J Mol Neurosci 2008;35(3):253-258.