Alphab-crystallin expression in epiretinal membrane of human proliferative diabetic retinopathy

Retina

Volumn 32, Issue 6, 2012, Pages 1190-1196

  Dong, Zhenyu ^a   Kase, Satoru ^a   Ando, Ryo ^a   Fukuhara, Junichi ^a   Saito, Wataru ^a   Kanda, Atsuhiro ^a   Murata, Miyuki ^a   Noda, Kousuke ^a   Ishida, Susumu ^a  

^a HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

alphaB crystallin; neovascularization; proliferative diabetic retinopathy; vascular endothelial growth factor

Indexed keywords

CRYSTALLIN; PARAFFIN; PARAFORMALDEHYDE; PROTEIN ALPHAB CRYSTALLIN; UNCLASSIFIED DRUG; VASCULOTROPIN;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; CYTOPLASM; DIABETIC RETINOPATHY; ENDOTHELIUM CELL; EPIRETINAL MEMBRANE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOLOCALIZATION; IMMUNOREACTIVITY; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RETINA; RETINA BLOOD VESSEL; RETINA SURGERY; TISSUE SECTION;

ADULT; AGED; ALPHA-CRYSTALLIN B CHAIN; CYTOPLASM; DIABETIC RETINOPATHY; ENDOTHELIAL CELLS; EPIRETINAL MEMBRANE; HUMANS; IMMUNOHISTOCHEMISTRY; MIDDLE AGED; RETINA; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84861812691     PISSN: 0275004X     EISSN: 15392864     Source Type: Journal    
DOI: 10.1097/IAE.0b013e318233ab9c     Document Type: Article

References (29)

1. Wistow GJ, Piatigorsky J. Lens crystallins: the evolution and expression of proteins for a highly specialized tissue. Annu Rev Biochem 1988;57:479-504.
2. Kantorow M, Piatigorsky J. Phosphorylations of alpha A-and alpha B-crystallin. Int J Biol Macromol 1998;22:307-314.
3. Kase S, Parikh JG, Rao NA. Expression of alpha-crystallin in retinoblastoma. Arch Ophthalmol 2009;127:187-192.
4. Ousman SS, Tomooka BH, van Noort JM, et al. Protective and therapeutic. role for alphaB-crystallin in autoimmune demye-lination. Nature 2007;448:474-479.
5. Andley UP. Crystallins in the eye: function and pathology. Prog Retin Eye Res 2007;26:78-98.
6. Watanabe G, Kato S, Nakata H, et al. AlphaB-crystallin: a novel p53-target gene required for p53-dependent apoptosis. Cancer Sci 2009;100:2368-2375.
7. Kase S, Parikh JG, Rao NA. Expression of heat shock protein 27 and alpha-crystallins in human retinoblastoma after chemo-reduction. Br J Ophthalmol 2009;93:541-544.
8. Rigas PK, Kase S, Rao NA. Expression of alpha-crystallins in human sebaceous carcinoma of the eyelid. Eur J Ophthalmol 2009;19:702-707.
9. Kase S, He S, Sonoda S, et al. AlphaB-crystallin regulation. of angiogenesis by modulation of VEGF. Blood 2010;115: 3398-3406.
10. Dimberg A, Rylova S, Dieterich LC, et al. AlphaB-crystallin promotes tumor angiogenesis by increasing vascular survival during tube morphogenesis. Blood 2008;111:2015-2023.
11. Resnikoff S, Pascolini D, Etya'ale D, et al. Global data on visual impairment in the year 2002. Bull World Health Organ 2004;82:844-851.
12. Klein BE. Overview of epidemiologic studies of diabetic reti-nopathy. Ophthalmic Epidemiol 2007;14:179-183.
13. Aiello LP, Avery RL, Arrigg PG, et al. Vascular endothelial growth factor in ocular fluid of patients with diabetic retinop-athy and other retinal disorders. N Engl J Med 1994;331: 1480-1487.
14. Wirostko B, Wong TY, Simo R. Vascular endothelial growth factor and diabetic complications. Prog Retin Eye Res 2008; 27:608-621.
15. Aiello LP. Angiogenic pathways in diabetic retinopathy. N Engl J Med 2005;353:839-841.
16. Ghosh JG, Shenoy AK, Jr, Clark JI. Interactions between important regulatory proteins and human alphaB crystallin. Biochemistry 2007;46:6308-6317.
17. Abu El-Asrar AM, Struyf S, Opdenakker G, et al. Expression of stem cell factor/c-kit signaling pathway components in diabetic fibrovascular epiretinal membranes. Mol Vis 16:1098-1107.
18. Moyano JV, Evans JR, Chen F, et al. AlphaB-crystallin is a novel oncoprotein that predicts poor clinical outcome in breast cancer. J Clin Invest 2006;116:261-270.
19. Nakata K, Crabb JW, Hollyfield JG. Crystallin distribution in Bruch's membrane-choroid complex from AMD and age-matched donor eyes. Exp Eye Res 2005;80:821-826.
20. Johnson PT, Brown MN, Pulliam BC, et al. Synaptic pathology, altered gene expression, and degeneration in photorecep-tors impacted by drusen. Invest Ophthalmol Vis Sci 2005;46: 4788-4795.
21. Liu SQ, Kang J, Li CJ, et al. Differences in expression of retinal proteins between diabetic and normal rats. World J Gastroenterol 2007;13:2118-2124.
22. Fort PE, Freeman WM, Losiewicz MK, et al. The retinal pro-teome in experimental diabetic retinopathy: up-regulation of crystallins and reversal by systemic and periocular insulin. Mol Cell Proteomics 2009;8:767-779.
23. Xi J, Farjo R, Yoshida S, et al. A comprehensive analysis of the expression of crystallins in mouse retina. Mol Vis 2003;9: 410-419.
24. Ishida S, Shinoda K, Kawashima S, et al. Coexpression of VEGF receptors VEGF-R2 and neuropilin-1 in proliferative diabetic retinopathy. Invest Ophthalmol Vis Sci 2000;41:1649-1656.
25. Nishikawa T, Edelstein D, Du XL, et al. Normalizing mito-chondrial superoxide production blocks three pathways of hyperglycaemic damage. Nature 2000;404:787-790.
26. Gao BB, Clermont A, Rook S, et al. Extracellular carbonic anhydrase mediates hemorrhagic retinal and cerebral vascular permeability through prekallikrein activation. Nat Med 2007; 13:181-188.
27. Kase S, Saito W, Ohgami K, et al. Expression of erythropoietin receptor in human epiretinal membrane of proliferative diabetic retinopathy. Br J Ophthalmol 2007;91:1376-1378.
28. Shin JH, Kim SW, Lim CM, et al. AlphaB-crystallin suppresses oxidative stress-induced astrocyte apoptosis by inhibiting caspase-3 activation. Neurosci Res 2009;64:355-361.
29. Stegh AH, Kesari S, Mahoney JE, et al. Bcl2L12-mediated inhibition of effector caspase-3 and caspase-7 via distinct mechanisms in glioblastoma. Proc Natl Acad Sci USA 2008;105:10703-10708.