Transdifferentiation from cornea to lens in Xenopus laevis depends on BMP signalling and involves upregulation of Wnt signalling

BMC Developmental Biology

Volumn 11, Issue , 2011, Pages

  Day, Robert C ^a   Beck, Caroline W ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

XENOPUS LAEVIS;

BONE MORPHOGENETIC PROTEIN; CRYSTALLIN; FRIZZLED PROTEIN; XENOPUS PROTEIN;

ANIMAL; ARTICLE; BIOSYNTHESIS; CELL DIFFERENTIATION; CORNEA; CYTOLOGY; DNA MICROARRAY; GENETICS; LENS; METABOLISM; PHYSIOLOGY; PRENATAL DEVELOPMENT; REGENERATION; SIGNAL TRANSDUCTION; TRANSGENIC ANIMAL; WNT SIGNALING PATHWAY; XENOPUS LAEVIS;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; BONE MORPHOGENETIC PROTEINS; CELL DIFFERENTIATION; CORNEA; CRYSTALLINS; LENS, CRYSTALLINE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RECEPTORS, WNT; REGENERATION; SIGNAL TRANSDUCTION; WNT SIGNALING PATHWAY; XENOPUS LAEVIS; XENOPUS PROTEINS;

EID: 80052591181     PISSN: None     EISSN: 1471213X     Source Type: Journal    
DOI: 10.1186/1471-213X-11-54     Document Type: Article

References (69)

1. Beyond early development: Xenopus as an emerging model for the study of regenerative mechanisms. Beck CW, Izpisua Belmonte JC, Christen B, Dev Dyn 2009 238 1226 48 10.1002/dvdy.21890 19280606
2. Molecular and cellular aspects of amphibian lens regeneration. Henry JJ, Tsonis PA, Prog Retin Eye Res 2010 29 543 55 10.1016/j.preteyeres.2010.07.002 20638484
3. Lens regeneration from the cornea in Xenopus laevis. Freeman G, J Exp Zool 1963 154 39 65 10.1002/jez.1401540105 14066571
4. secondary lens formation from the cornea following implantation of larval tissues betwen the inner and outer cornea of Xenopus laevis tadpoles. Reeve JC, Wild AE, J Embrol Exp Morph 1981 63 121 132 (Pubitemid 11039714)
5. The role of neural retina in lens regeneration from cornea in larval Xenopus laevis. Filoni S, Bosco L, Cioni C, Acta Embryol Morphol Exp 1982 3 15 28 7170907 (Pubitemid 13125684)
6. Lens regeneration from cornea of larval Xenopus laevis in the presence of the lens. Reeve JG, Wild AE, J Embryol Exp Morphol 1978 48 205 14 311375 (Pubitemid 9077686)
7. Lens formation from cornea in the presence of the old lens in larval Xenopus laevis. Bosco L, Filoni S, Cioni C, J Exp Zool 1980 213 9 14 10.1002/jez.1402130103 7452196
8. Tissue interactions and lens-forming competence in the outer cornea of larval Xenopus laevis. Cannata SM, Arresta E, Bernardini S, Gargioli C, Filoni S, J Exp Zoolog Part A Comp Exp Biol 2003 299 161 71 12975804 (Pubitemid 37529042)
9. The lens-regenerating competence in the outer cornea and epidermis of larval Xenopus laevis is related to pax6 expression. Gargioli C, Giambra V, Santoni S, Bernardini S, Frezza D, Filoni S, Cannata SM, J Anat 2008 212 612 20 10.1111/j.1469-7580.2008.00891.x 18430088 (Pubitemid 351593966)
10. Lens regeneration in larval Xenopus laevis: experimental analysis of the decline in the regenerative capacity during development. Filoni S, Bernardini S, Cannata SM, D'Alessio A, Dev Biol 1997 187 13 24 10.1006/dbio.1997.8598 9224670 (Pubitemid 27359421)
11. Cornea-lens transdifferentiation in the anuran, Xenopus tropicalis. Henry JJ, Elkins MB, Dev Genes Evol 2001 211 377 87 10.1007/s004270100163 11685571 (Pubitemid 32927033)
12. Retina and lens regeneration in anuran amphibians. Filoni S, Semin Cell Dev Biol 2009 20 528 34 10.1016/j.semcdb.2008.11.015 19095070
13. Conservation of gene expression during embryonic lens formation and cornea-lens transdifferentiation in Xenopus laevis. Schaefer JJ, Oliver G, Henry JJ, Dev Dyn 1999 215 308 18 10.1002/(SICI)1097-0177(199908)215:4<308::AID- AJA3>3.0.CO;2-I 10417820 (Pubitemid 29377200)
14. Characterizing gene expression during lens formation in Xenopus laevis: evaluating the model for embryonic lens induction. Henry JJ, Carinato ME, Schaefer JJ, Wolfe AD, Walter BE, Perry KJ, Elbl TN, Dev Dyn 2002 224 168 85 10.1002/dvdy.10097 12112470 (Pubitemid 34569058)
15. Gene expression profiles of lens regeneration and development in Xenopus laevis. Malloch EL, Perry KJ, Fukui L, Johnson VR, Wever J, Beck CW, King MW, Henry JJ, Dev Dyn 2009 238 2340 56 10.1002/dvdy.21998 19681139
16. In vitro lens transdifferentiation of Xenopus laevis outer cornea induced by Fibroblast Growth Factor (FGF). Bosco L, Venturini G, Willems D, Development 1997 124 421 8 9053318 (Pubitemid 27101676)
17. Molecular pathways needed for regeneration of spinal cord and muscle in a vertebrate. Beck CW, Christen B, Slack JM, Dev Cell 2003 5 429 39 10.1016/S1534-5807(03)00233-8 12967562 (Pubitemid 37107672)
18. Requirement for Wnt and FGF signaling in Xenopus tadpole tail regeneration. Lin G, Slack JM, Dev Biol 2008 316 323 35 10.1016/j.ydbio.2008.01. 032 18329638
19. Identification of genes associated with regenerative success of Xenopus laevis hindlimbs. Pearl EJ, Barker D, Day RC, Beck CW, BMC Dev Biol 2008 8 66 10.1186/1471-213X-8-66 18570684
20. Temporal requirement for bone morphogenetic proteins in regeneration of the tail and limb of Xenopus tadpoles. Beck CW, Christen B, Barker D, Slack JM, Mech Dev 2006 123 674 88 10.1016/j.mod.2006.07.001 16938438 (Pubitemid 44419625)
21. EDEN and EDEN-BP, a cis element and an associated factor that mediate sequence-specific mRNA deadenylation in Xenopus embryos. Paillard L, Omilli F, Legagneux V, Bassez T, Maniey D, Osborne HB, EMBO J 1998 17 278 87 10.1093/emboj/17.1.278 9427761 (Pubitemid 28041068)
22. Localization of lens intrinsic membrane protein MP19 and mutant protein MP19(To3) using fluorescent expression vectors. Chen T, Li X, Yang Y, Church RL, Mol Vis 2002 8 372 88 12379840 (Pubitemid 36153628)
23. A missense mutation in LIM2 causes autosomal recessive congenital cataract. Ponnam SP, Ramesha K, Tejwani S, Matalia J, Kannabiran C, Mol Vis 2008 14 1204 8 18596884 (Pubitemid 351943714)
24. Pax-6 and Prox 1 expression during lens regeneration from Cynops iris and Xenopus cornea: evidence for a genetic program common to embryonic lens development. Mizuno N, Mochii M, Yamamoto TS, Takahashi TC, Eguchi G, Okada TS, Differentiation 1999 65 141 9 10.1046/j.1432-0436.1999.6530141.x 10631811
25. Molecular anatomy of placode development in Xenopus laevis. Schlosser G, Ahrens K, Dev Biol 2004 271 439 66 10.1016/j.ydbio.2004.04.013 15223346 (Pubitemid 38833673)
26. A versatile transcriptional effector of Wingless signaling. Nusse R, Cell 1997 89 321 3 10.1016/S0092-8674(00)80210-X 9150130 (Pubitemid 27220875)
27. Conserved roles for Oct4 homologues in maintaining multipotency during early vertebrate development. Morrison GM, Brickman JM, Development 2006 133 2011 22 10.1242/dev.02362 16651543 (Pubitemid 43881266)
28. Bmp signaling is required for development of primary lens fiber cells. Faber SC, Robinson ML, Makarenkova HP, Lang RA, Development 2002 129 3727 37 12117821
29. BMP7 acts in murine lens placode development. Wawersik S, Purcell P, Rauchman M, Dudley AT, Robertson EJ, Maas R, Dev Biol 1999 207 176 88 10.1006/dbio.1998.9153 10049573 (Pubitemid 29117809)
30. BMP4 is essential for lens induction in the mouse embryo. Furuta Y, Hogan BL, Genes Dev 1998 12 3764 75 10.1101/gad.12.23.3764 9851982 (Pubitemid 29019656)
31. Interplay of Pax6 and SOX2 in lens development as a paradigm of genetic switch mechanisms for cell differentiation. Kondoh H, Uchikawa M, Kamachi Y, Int J Dev Biol 2004 48 819 27 10.1387/ijdb.041868hk 15558474 (Pubitemid 40039173)
32. Overexpression of the transcription factor Msx1 is insufficient to drive complete regeneration of refractory stage Xenopus laevis hindlimbs. Barker DM, Beck CW, Dev Dyn 2009 238 1366 78 10.1002/dvdy.21923 19322766
33. A Xenopus DNA microarray approach to identify novel direct BMP target genes involved in early embryonic development. Peiffer DA, Von Bubnoff A, Shin Y, Kitayama A, Mochii M, Ueno N, Cho KW, Dev Dyn 2005 232 445 56 10.1002/dvdy.20230 15614776 (Pubitemid 40129798)
34. Expression profiles during dedifferentiation in newt lens regeneration revealed by expressed sequence tags. Maki N, Martinson J, Nishimura O, Tarui H, Meller J, Tsonis PA, Agata K, Mol Vis 2010 16 72 8 20090923
35. BMP inhibition-driven regulation of six-3 underlies induction of newt lens regeneration. Grogg MW, Call MK, Okamoto M, Vergara MN, Del Rio-Tsonis K, Tsonis PA, Nature 2005 438 858 62 10.1038/nature04175 16341014 (Pubitemid 41753068)
36. A role for Wnt/beta-catenin signaling in lens epithelial differentiation. Stump RJ, Ang S, Chen Y, von Bahr T, Lovicu FJ, Pinson K, de Iongh RU, Yamaguchi TP, Sassoon DA, McAvoy JW, Dev Biol 2003 259 48 61 10.1016/S0012-1606(03)00179-9 12812787 (Pubitemid 36705527)
37. Spatial and temporal expression of Wnt and Dickkopf genes during murine lens development. Ang SJ, Stump RJ, Lovicu FJ, McAvoy JW, Gene Expr Patterns 2004 4 289 95 10.1016/j.modgep.2003.11.002 15053977 (Pubitemid 38397006)
38. Expression of Frizzleds and secreted frizzled-related proteins (Sfrps) during mammalian lens development. Chen Y, Stump RJ, Lovicu FJ, McAvoy JW, Int J Dev Biol 2004 48 867 77 10.1387/ijdb.041882yc 15558478 (Pubitemid 40039177)
39. Characterization of Wnt signaling components and activation of the Wnt canonical pathway in the murine retina. Liu H, Mohamed O, Dufort D, Wallace VA, Dev Dyn 2003 227 323 34 10.1002/dvdy.10315 12815618 (Pubitemid 36828753)
40. Mapping canonical Wnt signaling in the developing and adult retina. Liu H, Thurig S, Mohamed O, Dufort D, Wallace VA, Invest Ophthalmol Vis Sci 2006 47 5088 97 10.1167/iovs.06-0403 17065530 (Pubitemid 46586416)
41. A role for Wnt/planar cell polarity signaling during lens fiber cell differentiation? Chen Y, Stump RJ, Lovicu FJ, McAvoy JW, Semin Cell Dev Biol 2006 17 712 25 10.1016/j.semcdb.2006.11.005 17210263 (Pubitemid 46137022)
42. Wnt signaling is required for organization of the lens fiber cell cytoskeleton and development of lens three-dimensional architecture. Chen Y, Stump RJ, Lovicu FJ, Shimono A, McAvoy JW, Dev Biol 2008 324 161 76 10.1016/j.ydbio.2008.09.002 18824165
43. Determinative roles of FGF and Wnt signals in iris-derived lens regeneration in newt eye. Hayashi T, Mizuno N, Kondoh H, Dev Growth Differ 2008 50 279 87 10.1111/j.1440-169X.2008.01005.x 18336581 (Pubitemid 351661155)
44. Determinative role of Wnt signals in dorsal iris-derived lens regeneration in newt eye. Hayashi T, Mizuno N, Takada R, Takada S, Kondoh H, Mech Dev 2006 123 793 800 10.1016/j.mod.2006.08.009 17030116 (Pubitemid 44709505)
45. Functional analysis of Pitx during asexual regeneration in a basal chordate. Tiozzo S, De Tomaso AW, Evol Dev 2009 11 152 62 10.1111/j.1525-142X. 2009.00316.x 19245547
46. The Axenfeld syndrome and the Rieger syndrome. Fitch N, Kaback M, J Med Genet 1978 15 30 4 10.1136/jmg.15.1.30 416212 (Pubitemid 8273804)
47. Cloning and characterization of a novel bicoid-related homeobox transcription factor gene, RIEG, involved in Rieger syndrome. Semina EV, Reiter R, Leysens NJ, Alward WL, Small KW, Datson NA, Siegel-Bartelt J, Bierke-Nelson D, Bitoun P, Zabel BU, et al. Nat Genet 1996 14 392 9 10.1038/ng1296-392 8944018 (Pubitemid 26414582)
48. Autosomal dominant iris hypoplasia is caused by a mutation in the Rieger syndrome (RIEG/PITX2) gene. Alward WL, Semina EV, Kalenak JW, Heon E, Sheth BP, Stone EM, Murray JC, Am J Ophthalmol 1998 125 98 100 10.1016/S0002-9394(99) 80242-6 9437321 (Pubitemid 28049039)
49. A mutation in the RIEG1 gene associated with Peters' anomaly. Doward W, Perveen R, Lloyd IC, Ridgway AE, Wilson L, Black GC, J Med Genet 1999 36 152 5 10051017 (Pubitemid 29101394)
50. Mutation in PITX2 is associated with ring dermoid of the cornea. Xia K, Wu L, Liu X, Xi X, Liang D, Zheng D, Cai F, Pan Q, Long Z, Dai H, et al. J Med Genet 2004 41 129 10.1136/jmg.2004.022434 15591271
51. Recurrent 17 bp duplication in PITX3 is primarily associated with posterior polar cataract (CPP4). Berry V, Yang Z, Addison PK, Francis PJ, Ionides A, Karan G, Jiang L, Lin W, Hu J, Yang R, et al. J Med Genet 2004 41 109 10.1136/jmg.2004.020289 15286169
52. Pitx genes during cardiovascular development. Kioussi C, Briata P, Baek SH, Wynshaw-Boris A, Rose DW, Rosenfeld MG, Cold Spring Harb Symp Quant Biol 2002 67 81 7 10.1101/sqb.2002.67.81 12858527 (Pubitemid 36775498)
53. Ontogeny and localization of the crystallins during embryonic lens development in Xenopus laevis. McDevitt DS, Brahma SK, J Exp Zool 1973 186 127 40 10.1002/jez.1401860204 4201078
54. Lens regeneration in Xenopus is not a mere repeat of lens development, with respect to crystallin gene expression. Mizuno N, Mochii M, Takahashi TC, Eguchi G, Okada TS, Differentiation 1999 64 143 9 10.1046/j.1432-0436.1999. 6430143.x 10234811 (Pubitemid 29213880)
55. Distinct roles of maf genes during Xenopus lens development. Ishibashi S, Yasuda K, Mech Dev 2001 101 155 66 10.1016/S0925-4773(00)00585-2 11231068 (Pubitemid 32186319)
56. Domain disruption and mutation of the bZIP transcription factor, MAF, associated with cataract, ocular anterior segment dysgenesis and coloboma. Jamieson RV, Perveen R, Kerr B, Carette M, Yardley J, Heon E, Wirth MG, van Heyningen V, Donnai D, Munier F, et al. Hum Mol Genet 2002 11 33 42 10.1093/hmg/11.1.33 11772997 (Pubitemid 34100766)
57. Mutations in the human forkhead transcription factor FOXE3 associated with anterior segment ocular dysgenesis and cataracts. Semina EV, Brownell I, Mintz-Hittner HA, Murray JC, Jamrich M, Hum Mol Genet 2001 10 231 6 10.1093/hmg/10.3.231 11159941 (Pubitemid 32123981)
58. Deconstructing myotonic dystrophy. Tapscott SJ, Science 2000 289 1701 2 10.1126/science.289.5485.1701 11001736
59. Changes in global histone modifications during dedifferentiation in newt lens regeneration. Maki N, Tsonis PA, Agata K, Mol Vis 2010 16 1893 7 21031136
60. Expression of stem cell pluripotency factors during regeneration in newts. Maki N, Suetsugu-Maki R, Tarui H, Agata K, Del Rio-Tsonis K, Tsonis PA, Dev Dyn 2009 238 1613 6 10.1002/dvdy.21959 19384853
61. Regeneration and reprogramming compared. Christen B, Robles V, Raya M, Paramonov I, Belmonte JC, BMC Biol 2010 8 5 10.1186/1741-7007-8-5 20089153
62. Transgenic Xenopus embryos from sperm nuclear transplantations reveal FGF signaling requirements during gastrulation. Kroll KL, Amaya E, Development 1996 122 3173 83 8898230 (Pubitemid 26371982)
63. NCBI Gene Expression Omnibus. http://www.ncbi.nlm.nih.gov/geo/
64. affylmGUI: a graphical user interface for linear modeling of single channel microarray data. Wettenhall JM, Simpson KM, Satterley K, Smyth GK, Bioinformatics 2006 22 897 9 10.1093/bioinformatics/btl025 16455752
65. BAR duplicate remover tool. http://www.bar.utoronto.ca/ntools/cgi-bin/ ntools-duplicate-remover.cgi
66. GeneMerge - post-genomic analysis, data mining, and hypothesis testing. Castillo-Davis CI, Hartl DL, Bioinformatics 2003 19 891 2 10.1093/ bioinformatics/btg114 12724301 (Pubitemid 36582407)
67. NCBI Spidey mRNA to genomic alignment tool. http://www.ncbi.nlm.nih.gov/ spidey/index.html
68. JGI Xenopus tropicalis genome. http://genome.jgi-psf.org/Xentr4/Xentr4. home.html
69. Analysis of the developing Xenopus tail bud reveals separate phases of gene expression during determination and outgrowth. Beck CW, Slack JM, Mech Dev 1998 72 41 52 10.1016/S0925-4773(98)00015-X 9533951 (Pubitemid 28186705)