A retinal proteomics-based study identifies αA-crystallin as a sex steroid-regulated protein

Proteomics

Volumn 11, Issue 5, 2011, Pages 986-990

  D'Anna, Claudia ^a   Cascio, Caterina ^a   Cigna, Diego ^a   Galizzi, Giacoma ^a   Deidda, Irene ^a   Bianchi, Laura ^b   Russo, Domenica ^a   Passantino, Rosa ^a   Bini, Luca ^b   Guarneri, Patrizia ^a  

^a CNR   (Italy)

^b UNIVERSITY OF SIENA   (Italy)

Author keywords

A crystallin; Biomedicine; Dihydrotestosterone; Estradiol; Protein misfolding diseases; Retinal proteome

Indexed keywords

ALPHA CRYSTALLIN; ANDROSTANOLONE; ESTRADIOL; FATTY ACID; FATTY ACID BINDING PROTEIN EPIDERMAL 5 PROTEIN; GALECTIN; GALECTIN RELATED INTER FIBER PROTEIN; HEAT SHOCK PROTEIN; SEX HORMONE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; ESTROGEN ACTIVITY; FATTY ACID TRANSPORT; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DENATURATION; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN PROCESSING; PROTEOMICS; RETINA; STRESS; TWO DIMENSIONAL ELECTROPHORESIS; WESTERN BLOTTING;

ALPHA-CRYSTALLIN A CHAIN; ALTERNATIVE SPLICING; AMINO ACID SUBSTITUTION; ANIMALS; BLOTTING, WESTERN; DIHYDROTESTOSTERONE; ESTRADIOL; EYE PROTEINS; FATTY ACID-BINDING PROTEINS; GALECTINS; GENE EXPRESSION; GENE EXPRESSION PROFILING; INTRAVITREAL INJECTIONS; MALE; NERVE TISSUE PROTEINS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEOMICS; RATS; RETINA; RETINAL DISEASES; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

RATTUS;

EID: 79951761475     PISSN: 16159853     EISSN: 16159861     Source Type: Journal    
DOI: 10.1002/pmic.201000561     Document Type: Article

References (28)

1. Gupta, P. D., Johar, K., Sr., Nagpal, K., Vasavada, A. R., Sex hormone receptors in the human eye. Surv. Ophthalmol. 2005, 50, 274-284.
2. Surguchev, A., Surguchov, A., Conformational diseases: looking into the eyes. Brain Res. Bull. 2010, 81, 12-24.
3. Feskanich, D., Cho, E., Schaumberg, D. A., Colditz, G. A., Hankinson, S. E., Menopausal and reproductive factors and risk of age-related macular degeneration. Arch. Ophthalmol. 2008, 126, 519-524.
4. Haan, M. N., Klein, R., Klein, B. E., Deng, Y. et al., Hormone therapy and age-related macular degeneration. Arch. Ophthalmol. 2006, 124, 988-992.
5. Pike, C. J., Carroll, J. C., Rosario, E. R., Barron, A. M., Protective actions of sex steroid hormones in Alzheimer's disease. Front. Neuroendocrinol. 2009, 30, 239-258.
6. Tamer, C., Oksuz, H., Sogut, S., Androgen status of the nonautoimmune dry eye subtypes. Ophthalmic. Res. 2006, 38, 280-286.
7. Guarneri, P., Cascio, C., Russo, D., D'Agostino, S. et al., Neurosteroids in the retina: neurodegenerative and neuroprotective agents in retinal degeneration. Ann. N. Y. Acad. Sci. 2003, 1007, 117-128.
8. Cascio, C., Russo, D., Drago, G., Galizzi, G. et al., 17β-Estradiol synthesis in the adult male rat retina. Exp. Eye Res. 2007, 85, 166-172.
9. Nonaka, A., Kiryu, J., Tsujikawa, A., Yamashiro, K. et al., Administration of 17β-estradiol attenuates retinal ischemia-reperfusion injury in rats. Invest. Ophthalmol. Vis. Sci. 2000, 41, 2689-2696.
10. Bucolo, C., Drago, F., Effects of neuroactive steroids on ischemia-reperfusion injury in the rat retina: role of σ1 recognition sites. Eur. J. Pharmacol. 2004, 498, 111-114.
11. Peyman, G. A., Lad, E. M., Moshfeghi, D. M., Intravitreal injection of therapeutic agents. Retina 2009, 29, 875-912.
12. Barton, K. A., Hsu, C. D., Petrash, J. M., Interactions between small heat shock protein α-crystallin and galectin-related interfiber protein (GRIFIN) in the ocular lens. Biochemistry 2009, 48, 3956-3966.
13. Sellner, P., Developmental regulation of fatty acid binding protein in neural tissue. Dev. Dyn. 1994, 200, 333-339.
14. Kapphahn, R. J., Giwa, B. M., Berg, K. M., Roehrich, H. et al., Retinal proteins modified by 4-hydroxynonenal: identification of molecular targets. Exp. Eye Res. 2006, 83, 165-175.
15. Andley, U. P., Crystallins in the eye: function and pathology. Prog. Retin. Eye Res. 2007, 26, 78-98.
16. Ethen C. M., Reilly, C., Feng X., Olsen, T. W., Ferrington, D. A., The proteome of central and peripheral retina with progression of age-related macular degeneration. Invest. Ophthalmol. Vis. Sci. 2006, 47, 2280-2290.
17. Fort, P. E., Freeman, W. M., Losiewicz, M. K., Singh, R. S., Gardner, T. W., The retinal proteome in experimental diabetic retinopathy: up-regulation of crystallins and reversal by systemic and periocular insulin. Mol. Cell. Proteomics 2009, 8, 767-779.
18. Munemasa, Y., Kwong, J. M., Caprioli, J., Piri, N., The role of alphaA- and alphaB-crystallins in the survival of retinal ganglion cells after optic nerve axotomy. Invest. Ophthalmol. Vis. Sci. 2009, 50, 3869-3875.
19. Ecroyd, H., Carver, J. A., Crystallin proteins and amyloid fibrils. Cell. Mol. Life Sci. 2009, 66, 62-81.
20. Schaefer, H., Chamrad, D. C., Herrmann, M., Stuwe, J. et al., Study of posttranslational modifications in lenticular alphaA-crystallin of mice using proteomic analysis techniques. Biochim. Biophys. Acta 2006, 1764, 1948-1962.
21. Rose, K., Schröer, U., Volk, G. F., Schlatt, S. et al., Axonal regeneration in the organotypically cultured monkey retina: biological aspects, dependence on substrates and age-related proteomic profiling. Restor. Neurol. Neurosci. 2008, 26, 249-266.
22. Simpanya, M. F., Wistow, G., Gao, J., David, L. L. et al., Expressed sequence tag analysis of guinea pig (Cavia porcellus) eye tissues for NEIBank. Mol. Vis. 2008, 14, 2413-2427.
23. Kosano, H., Nishigori, H., Steroid-induced cataract: other than in the whole animal system, in the lens culture system, androgens, estrogens and progestins as well as glucocorticoids produce a loss of transparency of the lens. Dev. Ophthalmol. 2002, 35, 161-168.
24. Brinton, R. D., The healthy cell bias of estrogen action: mitochondrial bioenergetics and neurological implications. Trends Neurosci. 2008, 31, 529-537.
25. Tillement, J. P., Lecanu, L., Papadopoulos, V., Amyloidosis and neurodegenerative diseases: current treatments and new pharmacological options. Pharmacology 2010, 85, 1-17.
26. Ding, J. D., Lin, J., Mace, B. E., Herrmann, R. et al., Targeting age-related macular degeneration with Alzheimer's disease based immunotherapies: anti-amyloid-beta antibody attenuates pathologies in an age-related macular degeneration mouse model. Vision Res. 2008, 48, 339-345.
27. Guarneri, P., Corda, M. G., Concas, A., Biggio, G., Kainic acid-induced lesion of rat retina: differential effect on cyclic GMP and benzodiazepine and GABA receptors. Brain Res. 1981, 209, 216-220.
28. Candiano, G., Bruschi, M., Pedemonte, N., Musante, L. et al., Proteomic analysis of the airway surface liquid: modulation by proinflammatory cytokines. Am. J. Physiol. Lung Cell. Mol. Physiol. 2007, 292, L185-L198.