Targeted knockout of the mouse βB2-crystallin gene (Crybb2) induces age-related cataract

Investigative Ophthalmology and Visual Science

Volumn 49, Issue 12, 2008, Pages 5476-5483

  Zhang, Jun ^a   Li, Jing ^b   Huang, Caiguo ^b   Xue, Lian ^a   Peng, Yajun ^a   Fu, Qing ^a   Gao, Li ^a   Zhang, Jianrong ^a   Li, Wenjie ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CRYSTALLIN; BETA2 CRYSTALLIN B CHAIN; UNCLASSIFIED DRUG; BETA CRYSTALLIN B2; BETA-CRYSTALLIN B2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOMICROSCOPY; CATARACT; CONTROLLED STUDY; DENATURATION; DISEASE SEVERITY; EMBRYONIC STEM CELL; EYE AXIS LENGTH; GENE DELETION; GENE DISRUPTION; GENE EXPRESSION; GENE FUNCTION; GENE STRUCTURE; GENE TARGETING; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; KNOCKOUT GENE; LENS; MOUSE; NONHUMAN; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SLIT LAMP; SUPERNATANT; THERMOSTABILITY; TISSUE HOMOGENATE; TRANSMISSION ELECTRON MICROSCOPY; TWO DIMENSIONAL GEL ELECTROPHORESIS; WESTERN BLOTTING; WILD TYPE; AGING; ANIMAL; C57BL MOUSE; ENZYME IMMUNOASSAY; GENE INACTIVATION; GENE SILENCING; GENETICS; HEAT; METABOLISM; MOUSE MUTANT; PATHOLOGY; PHYSIOLOGY; PROTEIN DENATURATION; ULTRASTRUCTURE;

AGING; ANIMALS; BETA-CRYSTALLIN B CHAIN; BLOTTING, WESTERN; CATARACT; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; EMBRYONIC STEM CELLS; GENE EXPRESSION; GENE KNOCKOUT TECHNIQUES; GENE SILENCING; HOT TEMPERATURE; IMMUNOENZYME TECHNIQUES; LENS, CRYSTALLINE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, ELECTRON, SCANNING; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; PROTEIN DENATURATION;

EID: 58149229871     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.08-2179     Document Type: Article

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