-
1
-
-
34548295338
-
Origin and Evolution of High Throughput Screening
-
Pereira D., Williams J.. Origin and Evolution of High Throughput Screening. Br. J. Pharmacol. 2007 ; 152 (1). 53-61
-
(2007)
Br. J. Pharmacol
, vol.152
, Issue.1
, pp. 53-61
-
-
Pereira, D.1
Williams, J.2
-
2
-
-
77249176182
-
Rethinking Screening
-
Kodadek T.. Rethinking Screening. Nat. Chem. Biol. 2010 ; 6 (3). 162-165
-
(2010)
Nat. Chem. Biol
, vol.6
, Issue.3
, pp. 162-165
-
-
Kodadek, T.1
-
3
-
-
84867928657
-
System-Based Drug Discovery within the Human Kinome
-
Bamborough P.. System-Based Drug Discovery within the Human Kinome. Expert Opin. Drug Discov. 2012 ; 7 (11). 1053-1070
-
(2012)
Expert Opin. Drug Discov
, vol.7
, Issue.11
, pp. 1053-1070
-
-
Bamborough, P.1
-
4
-
-
84863319209
-
Bacterial Expression of Mutant Argininosuccinate Lyase Reveals Imperfect Correlation of in-Vitro Enzyme Activity with Clinical Phenotype in Argininosuccinic Aciduria
-
Engel K., Vuissoz J.-M., Eggimann S., et al. Bacterial Expression of Mutant Argininosuccinate Lyase Reveals Imperfect Correlation of in-Vitro Enzyme Activity with Clinical Phenotype in Argininosuccinic Aciduria. J. Inher. Metab. Dis. 2012 ; 35 (1). 133-140
-
(2012)
J. Inher. Metab. Dis
, vol.35
, Issue.1
, pp. 133-140
-
-
Engel, K.1
Vuissoz, J.-M.2
Eggimann, S.3
-
5
-
-
84862544670
-
Expression of Recombinant Ara h 6 in Pichia pastoris but Not in Escherichia coli Preserves Allergic Effector Function and Allows Assessment of Specific Mutations
-
Zhuang Y., Durrani S., Hodges B., et al. Expression of Recombinant Ara h 6 in Pichia pastoris but Not in Escherichia coli Preserves Allergic Effector Function and Allows Assessment of Specific Mutations. Molec. Nutr. Food Res. 2012 ; 56 (6). 986-995
-
(2012)
Molec. Nutr. Food Res
, vol.56
, Issue.6
, pp. 986-995
-
-
Zhuang, Y.1
Durrani, S.2
Hodges, B.3
-
6
-
-
69249218864
-
Design, Synthesis and Selection of DNA-Encoded Small-Molecule Libraries
-
Clark M. A., Acharya R. A., Arico-Muendel C. C., et al. Design, Synthesis and Selection of DNA-Encoded Small-Molecule Libraries. Nat. Chem. Biol. 2009 ; 5 (9). 647-654
-
(2009)
Nat. Chem. Biol
, vol.5
, Issue.9
, pp. 647-654
-
-
Clark, M.A.1
Acharya, R.A.2
Arico-Muendel, C.C.3
-
7
-
-
71949130633
-
Review Article: High-Throughput Affinity-Based Technologies for Small-Molecule Drug Discovery
-
Zhu Z., Cuozzo J.. Review Article: High-Throughput Affinity-Based Technologies for Small-Molecule Drug Discovery. J. Biomol. Screen. 2009 ; 14 (10). 1157-1164
-
(2009)
J. Biomol. Screen
, vol.14
, Issue.10
, pp. 1157-1164
-
-
Zhu, Z.1
Cuozzo, J.2
-
8
-
-
77955947553
-
Recent Advances in the Production of Proteins in Insect and Mammalian Cells for Structural Biology
-
Nettleship J., Assenberg R., Diprose J., et al. Recent Advances in the Production of Proteins in Insect and Mammalian Cells for Structural Biology. J. Struct. Biol. 2010 ; 172 (1). 55-65
-
(2010)
J. Struct. Biol
, vol.172
, Issue.1
, pp. 55-65
-
-
Nettleship, J.1
Assenberg, R.2
Diprose, J.3
-
10
-
-
70749134529
-
Identifying Druggable Disease-Modifying Gene Products
-
Dixon S., Stockwell B.. Identifying Druggable Disease-Modifying Gene Products. Curr. Opin. Chem. Biol. 2009 ; 13 (5-6). 549-555
-
(2009)
Curr. Opin. Chem. Biol
, vol.13
, Issue.56
, pp. 549-555
-
-
Dixon, S.1
Stockwell, B.2
-
12
-
-
77952543008
-
Selecting Chemicals: The Emerging Utility of DNA-Encoded Libraries
-
Clark M. A.. Selecting Chemicals: The Emerging Utility of DNA-Encoded Libraries. Curr. Opin. Chem. Biol. 2010 ; 14 (3). 396-403
-
(2010)
Curr. Opin. Chem. Biol
, vol.14
, Issue.3
, pp. 396-403
-
-
Clark, M.A.1
-
13
-
-
37549040575
-
The Challenge of Drugging Undruggable Targets in Cancer: Lessons Learned from Targeting BCL-2 Family Members
-
Verdine G., Walensky L.. The Challenge of Drugging Undruggable Targets in Cancer: Lessons Learned from Targeting BCL-2 Family Members. Clin. Cancer Res. 2007 ; 13 (24). 7264-7270
-
(2007)
Clin. Cancer Res
, vol.13
, Issue.24
, pp. 7264-7270
-
-
Verdine, G.1
Walensky, L.2
-
14
-
-
77953699074
-
Targeting the Undruggable Proteome: The Small Molecules of My Dreams
-
Crews C.. Targeting the Undruggable Proteome: The Small Molecules of My Dreams. Chem. Biol. 2010 ; 17 (6). 551-555
-
(2010)
Chem. Biol
, vol.17
, Issue.6
, pp. 551-555
-
-
Crews, C.1
-
15
-
-
84856370676
-
Pocketome: An Encyclopedia of Small-Molecule Binding Sites in 4D
-
Kufareva I., Ilatovskiy A., Abagyan R.. Pocketome: An Encyclopedia of Small-Molecule Binding Sites in 4D. Nucl. Acids Res. 2012 ; 40 (Database issue). 40
-
(2012)
Nucl. Acids Res
, vol.40
, pp. 40
-
-
Kufareva, I.1
Ilatovskiy, A.2
Abagyan, R.3
-
16
-
-
0035882103
-
The PIF-Binding Pocket in PDK1 Is Essential for Activation of S6K and SGK, but Not PKB
-
Biondi R., Kieloch A., Currie R., et al. The PIF-Binding Pocket in PDK1 Is Essential for Activation of S6K and SGK, but Not PKB. EMBO J. 2001 ; 20 (16). 4380-4390
-
(2001)
EMBO J
, vol.20
, Issue.16
, pp. 4380-4390
-
-
Biondi, R.1
Kieloch, A.2
Currie, R.3
-
17
-
-
77953305214
-
Discovery of PDK1 Kinase Inhibitors with a Novel Mechanism of Action by Ultrahigh Throughput Screening
-
Bobkova E., Weber M., Xu Z., et al. Discovery of PDK1 Kinase Inhibitors with a Novel Mechanism of Action by Ultrahigh Throughput Screening. J. Biol. Chem. 2010 ; 285 (24). 18838-18846
-
(2010)
J. Biol. Chem
, vol.285
, Issue.24
, pp. 18838-18846
-
-
Bobkova, E.1
Weber, M.2
Xu, Z.3
-
18
-
-
84863825248
-
Small Molecule Modulators of Keap1-Nrf2-ARE Pathway as Potential Preventive and Therapeutic Agents
-
Magesh S., Chen Y., Hu L.. Small Molecule Modulators of Keap1-Nrf2-ARE Pathway as Potential Preventive and Therapeutic Agents. Med. Res. Rev. 2012 ; 32 (4). 687-726
-
(2012)
Med. Res. Rev
, vol.32
, Issue.4
, pp. 687-726
-
-
Magesh, S.1
Chen, Y.2
Hu, L.3
-
19
-
-
79952749190
-
NRF2 Blockade Suppresses Colon Tumor Angiogenesis by Inhibiting Hypoxia-Induced Activation of HIF-1
-
Kim T.-H., Hur E.-G., Kang S.-J., et al. NRF2 Blockade Suppresses Colon Tumor Angiogenesis by Inhibiting Hypoxia-Induced Activation of HIF-1. Cancer Res. 2011 ; 71 (6). 2260-2275
-
(2011)
Cancer Res
, vol.71
, Issue.6
, pp. 2260-2275
-
-
Kim, T.-H.1
Hur, E.-G.2
Kang, S.-J.3
-
20
-
-
84861088185
-
Anti-Inflammatory Effect of a Cell-Penetrating Peptide Targeting the Nrf2/Keap1 Interaction
-
Steel R., Cowan J., Payerne E., et al. Anti-Inflammatory Effect of a Cell-Penetrating Peptide Targeting the Nrf2/Keap1 Interaction. ACS Med. Chem. Lett. 2012 ; 3 (5). 407-410
-
(2012)
ACS Med. Chem. Lett
, vol.3
, Issue.5
, pp. 407-410
-
-
Steel, R.1
Cowan, J.2
Payerne, E.3
-
21
-
-
84864085622
-
Mechanism of Cullin3 E3 Ubiquitin Ligase Dimerization
-
Choo Y., Hagen T.. Mechanism of Cullin3 E3 Ubiquitin Ligase Dimerization. PloS One. 2012 ; 7 (7). e41350
-
(2012)
PloS One
, vol.7
, Issue.7
, pp. 41350
-
-
Choo, Y.1
Hagen, T.2
-
22
-
-
11144244006
-
Crystal Structure of the Kelch Domain of Human Keap1
-
Li X., Zhang D., Hannink M., et al. Crystal Structure of the Kelch Domain of Human Keap1. J. Biol. Chem. 2004 ; 279 (52). 54750-54758
-
(2004)
J. Biol. Chem
, vol.279
, Issue.52
, pp. 54750-54758
-
-
Li, X.1
Zhang, D.2
Hannink, M.3
-
23
-
-
84876680052
-
Discovery of a Small-Molecule Inhibitor and Cellular Probe of Keap1-Nrf2 Protein-Protein Interaction
-
Hu L., Magesh S., Chen L., et al. Discovery of a Small-Molecule Inhibitor and Cellular Probe of Keap1-Nrf2 Protein-Protein Interaction. Bioorg. Med. Chem. Lett. 2013 ; 23 (10). 3039-3043
-
(2013)
Bioorg. Med. Chem. Lett
, vol.23
, Issue.10
, pp. 3039-3043
-
-
Hu, L.1
Magesh, S.2
Chen, L.3
-
24
-
-
77956181585
-
High-Throughput Production of Human Proteins for Crystallization: The SGC Experience
-
Savitsky P., Bray J., Cooper C., et al. High-Throughput Production of Human Proteins for Crystallization: The SGC Experience. J. Struct. Biol. 2010 ; 172 (1). 3-13
-
(2010)
J. Struct. Biol
, vol.172
, Issue.1
, pp. 3-13
-
-
Savitsky, P.1
Bray, J.2
Cooper, C.3
-
26
-
-
0033578684
-
Protein Secondary Structure Prediction Based on Position-Specific Scoring Matrices
-
Jones D. T.. Protein Secondary Structure Prediction Based on Position-Specific Scoring Matrices. J. Mol. Biol. 1999 ; 292 (2). 195-202
-
(1999)
J. Mol. Biol
, vol.292
, Issue.2
, pp. 195-202
-
-
Jones, D.T.1
-
27
-
-
80052627407
-
Gene Design, Cloning and Protein-Expression Methods for High-Value Targets at the Seattle Structural Genomics Center for Infectious Disease
-
Raymond A., Haffner T., Ng N., et al. Gene Design, Cloning and Protein-Expression Methods for High-Value Targets at the Seattle Structural Genomics Center for Infectious Disease. Acta Crystallograph. F. 2011 ; 67 (Pt 9). 992-997
-
(2011)
Acta Crystallograph. F
, vol.67
, Issue.PART 9
, pp. 992-997
-
-
Raymond, A.1
Haffner, T.2
Ng, N.3
-
29
-
-
0035150079
-
Synonymous Codon Usage in Bacteria
-
Ermolaeva M.. Synonymous Codon Usage in Bacteria. Curr. Issues Molec. Biol. 2001 ; 3: 91-97
-
(2001)
Curr. Issues Molec. Biol
, vol.3
, pp. 91-97
-
-
Ermolaeva, M.1
-
30
-
-
33846105724
-
SGDB: A Database of Synthetic Genes Re-designed for Optimizing Protein Over-expression
-
Wu G., Zheng Y., Qureshi I., et al. SGDB: A Database of Synthetic Genes Re-designed for Optimizing Protein Over-expression. Nucleic Acids Res. 2007 ; 35 (Database issue). 9
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 9
-
-
Wu, G.1
Zheng, Y.2
Qureshi, I.3
-
32
-
-
77951734603
-
A Role for Codon Order in Translation Dynamics
-
Cannarozzi G., Cannarrozzi G., Schraudolph N., et al. A Role for Codon Order in Translation Dynamics. Cell. 2010 ; 141 (2). 355-367
-
(2010)
Cell
, vol.141
, Issue.2
, pp. 355-367
-
-
Cannarozzi, G.1
Cannarrozzi, G.2
Schraudolph, N.3
-
33
-
-
84886302057
-
Causes and Effects of N-Terminal Codon Bias in Bacterial Genes
-
Goodman D., Church G., Kosuri S.. Causes and Effects of N-Terminal Codon Bias in Bacterial Genes. Science (New York, N.Y.). 2013 ; 342 (6157). 475-479
-
(2013)
Science (New York, N.Y.)
, vol.342
, Issue.6157
, pp. 475-479
-
-
Goodman, D.1
Church, G.2
Kosuri, S.3
-
34
-
-
84890069561
-
Selection on Codon Bias in Yeast: A Transcriptional Hypothesis
-
Trotta E.. Selection on Codon Bias in Yeast: A Transcriptional Hypothesis. Nucleic Acids Res. 2013 ; 41 (20). 9382-9395
-
(2013)
Nucleic Acids Res
, vol.41
, Issue.20
, pp. 9382-9395
-
-
Trotta, E.1
-
35
-
-
84867732569
-
Speeding with Control: Codon Usage, tRNAs, and Ribosomes
-
Novoa E., Ribas de Pouplana L.. Speeding with Control: Codon Usage, tRNAs, and Ribosomes. Trends Genet. 2012 ; 28 (11). 574-581
-
(2012)
Trends Genet
, vol.28
, Issue.11
, pp. 574-581
-
-
Novoa, E.1
Ribas De Pouplana, L.2
-
36
-
-
62049083910
-
Transient Ribosomal Attenuation Coordinates Protein Synthesis and Co-translational Folding
-
Zhang G., Hubalewska M., Ignatova Z.. Transient Ribosomal Attenuation Coordinates Protein Synthesis and Co-translational Folding. Nat. Struct. Molec. Biol. 2009 ; 16 (3). 274-280
-
(2009)
Nat. Struct. Molec. Biol
, vol.16
, Issue.3
, pp. 274-280
-
-
Zhang, G.1
Hubalewska, M.2
Ignatova, Z.3
-
37
-
-
78049403925
-
Synonymous Codon Usage Influences the Local Protein Structure Observed
-
Saunders R., Deane C. M.. Synonymous Codon Usage Influences the Local Protein Structure Observed. Nucleic Acids Res. 2010 ; 38 (19). 6719-6728
-
(2010)
Nucleic Acids Res
, vol.38
, Issue.19
, pp. 6719-6728
-
-
Saunders, R.1
Deane, C.M.2
-
38
-
-
84863112436
-
Characterization of Coding Synonymous and Non-synonymous Variants in ADAMTS13 Using Ex Vivo and in Silico Approaches
-
Edwards N., Hing Z., Perry A., et al. Characterization of Coding Synonymous and Non-synonymous Variants in ADAMTS13 Using Ex Vivo and In Silico Approaches. PloS One. 2012 ; 7 (6). e38864
-
(2012)
PloS One
, vol.7
, Issue.6
, pp. 38864
-
-
Edwards, N.1
Hing, Z.2
Perry, A.3
-
39
-
-
84874722535
-
Non-optimal Codon Usage Is a Mechanism to Achieve Circadian Clock Conditionality
-
Xu Y., Ma P., Shah P., et al. Non-optimal Codon Usage Is a Mechanism to Achieve Circadian Clock Conditionality. Nature. 2013 ; 495 (7439). 116-120
-
(2013)
Nature
, vol.495
, Issue.7439
, pp. 116-120
-
-
Xu, Y.1
Ma, P.2
Shah, P.3
-
40
-
-
84874683740
-
Non-optimal Codon Usage Affects Expression, Structure and Function of Clock Protein FRQ
-
Zhou M., Guo J., Cha J., et al. Non-optimal Codon Usage Affects Expression, Structure and Function of Clock Protein FRQ. Nature. 2013 ; 495 (7439). 111-115
-
(2013)
Nature
, vol.495
, Issue.7439
, pp. 111-115
-
-
Zhou, M.1
Guo, J.2
Cha, J.3
-
41
-
-
33846504706
-
A "silent" Polymorphism in the MDR1 Gene Changes Substrate Specificity
-
Kimchi-Sarfaty C., Oh J., Kim I.-W., et al. A "Silent" Polymorphism in the MDR1 Gene Changes Substrate Specificity. Science (New York, N.Y.). 2007 ; 315 (5811). 525-528
-
(2007)
Science (New York, N.Y.)
, vol.315
, Issue.5811
, pp. 525-528
-
-
Kimchi-Sarfaty, C.1
Oh, J.2
Kim, I.-W.3
-
42
-
-
84860309632
-
Recombinant Protein Expression and Purification: A Comprehensive Review of Affinity Tags and Microbial Applications
-
Young C., Britton Z., Robinson A.. Recombinant Protein Expression and Purification: A Comprehensive Review of Affinity Tags and Microbial Applications. Biotechnology J. 2012 ; 7 (5). 620-634
-
(2012)
Biotechnology J
, vol.7
, Issue.5
, pp. 620-634
-
-
Young, C.1
Britton, Z.2
Robinson, A.3
-
43
-
-
84892689826
-
To Fuse or Not to Fuse: What Is Your Purpose?
-
Bell M. R., Engleka M. J., Malik A., et al. To Fuse or Not to Fuse: What Is Your Purpose?. Protein Sci. 2013 ; 22 (11). 1466-1477
-
(2013)
Protein Sci
, vol.22
, Issue.11
, pp. 1466-1477
-
-
Bell, M.R.1
Engleka, M.J.2
Malik, A.3
-
44
-
-
0011962568
-
Thioredoxin as a Fusion Partner for Production of Soluble Recombinant Proteins in Escherichia coli
-
LaVallie E. R., Lu Z., Diblasio-Smith E. A., et al. Thioredoxin as a Fusion Partner for Production of Soluble Recombinant Proteins in Escherichia coli. Methods Enzymol. 2000 ; 326: 322-340
-
(2000)
Methods Enzymol
, vol.326
, pp. 322-340
-
-
Lavallie, E.R.1
Lu, Z.2
Diblasio-Smith, E.A.3
-
45
-
-
3543073550
-
SUMO Fusions and SUMO-Specific Protease for Efficient Expression and Purification of Proteins
-
Malakhov M. P., Mattern M. R., Malakhova O. A., et al. SUMO Fusions and SUMO-Specific Protease for Efficient Expression and Purification of Proteins. J. Struct. Funct. Genomics. 2004 ; 5 (1-2). 75-86
-
(2004)
J. Struct. Funct. Genomics
, vol.5
, Issue.12
, pp. 75-86
-
-
Malakhov, M.P.1
Mattern, M.R.2
Malakhova, O.A.3
-
46
-
-
0033589826
-
New Fusion Protein Systems Designed to Give Soluble Expression in Escherichia coli
-
Davis G. D., Elisee C., Newham D. M., et al. New Fusion Protein Systems Designed to Give Soluble Expression in Escherichia coli. Biotechnol. Bioeng. 1999 ; 65 (4). 382-388
-
(1999)
Biotechnol. Bioeng
, vol.65
, Issue.4
, pp. 382-388
-
-
Davis, G.D.1
Elisee, C.2
Newham, D.M.3
-
47
-
-
0035900642
-
Control of Intrinsic Transcription Termination by N and NusA: The Basic Mechanisms
-
Gusarov I., Nudler E.. Control of Intrinsic Transcription Termination by N and NusA: The Basic Mechanisms. Cell. 2001 ; 107 (4). 437-449
-
(2001)
Cell
, vol.107
, Issue.4
, pp. 437-449
-
-
Gusarov, I.1
Nudler, E.2
-
48
-
-
80355123650
-
Expression Screening of Fusion Partners from an E. Coli Genome for Soluble Expression of Recombinant Proteins in a Cell-Free Protein Synthesis System
-
Ahn J.-H., Keum J.-W., Kim D.-M.. Expression Screening of Fusion Partners from an E. coli Genome for Soluble Expression of Recombinant Proteins in a Cell-Free Protein Synthesis System. PloS One. 2011 ; 6 (11). e26875
-
(2011)
PloS One
, vol.6
, Issue.11
, pp. 26875
-
-
Ahn, J.-H.1
Keum, J.-W.2
Kim, D.-M.3
-
49
-
-
0025287633
-
Expression as trpE Fusion
-
Yansura D. G.. Expression as trpE Fusion. Methods Enzymol. 1990 ; 185: 161-166
-
(1990)
Methods Enzymol
, vol.185
, pp. 161-166
-
-
Yansura, D.G.1
-
50
-
-
0028017482
-
Production, Purification, and Cleavage of Tandem Repeats of Recombinant Peptides
-
Athan K., Christopher T. W.. Production, Purification, and Cleavage of Tandem Repeats of Recombinant Peptides. JACS. 1994 ; 116: 4599-4607
-
(1994)
JACS
, vol.116
, pp. 4599-4607
-
-
Athan, K.1
Christopher, T.W.2
-
51
-
-
84864943653
-
A PagP Fusion Protein System for the Expression of Intrinsically Disordered Proteins in Escherichia coli
-
Hwang P. M., Pan J. S., Sykes B. D.. A PagP Fusion Protein System for the Expression of Intrinsically Disordered Proteins in Escherichia coli. Protein Expr. Purif. 2012 ; 85 (1). 148-151
-
(2012)
Protein Expr. Purif
, vol.85
, Issue.1
, pp. 148-151
-
-
Hwang, P.M.1
Pan, J.S.2
Sykes, B.D.3
-
52
-
-
60349118324
-
Cloning, Expression, Isotope Labeling, Purification, and Characterization of Bovine Antimicrobial Peptide, Lactophoricin in Escherichia coli
-
Park T.-J., Kim J.-S., Choi S.-S., et al. Cloning, Expression, Isotope Labeling, Purification, and Characterization of Bovine Antimicrobial Peptide, Lactophoricin in Escherichia coli. Protein Expr. Purif. 2009 ; 65 (1). 23-29
-
(2009)
Protein Expr. Purif
, vol.65
, Issue.1
, pp. 23-29
-
-
Park, T.-J.1
Kim, J.-S.2
Choi, S.-S.3
-
53
-
-
84892370557
-
Targeted Expression, Purification, and Cleavage of Fusion Proteins from Inclusion Bodies in Escherichia coli
-
Hwang P., Pan J., Sykes B.. Targeted Expression, Purification, and Cleavage of Fusion Proteins from Inclusion Bodies in Escherichia coli. FEBS Lett. 2013 ;:
-
(2013)
FEBS Lett
-
-
Hwang, P.1
Pan, J.2
Sykes, B.3
-
54
-
-
84863485837
-
An Expression and Purification System for the Biosynthesis of Adenosine Receptor Peptides for Biophysical and Structural Characterization
-
Britton Z. T., Hanle E. I., Robinson A. S.. An Expression and Purification System for the Biosynthesis of Adenosine Receptor Peptides for Biophysical and Structural Characterization. Protein Expr. Purif. 2012 ; 84 (2). 224-235
-
(2012)
Protein Expr. Purif
, vol.84
, Issue.2
, pp. 224-235
-
-
Britton, Z.T.1
Hanle, E.I.2
Robinson, A.S.3
-
55
-
-
77952504334
-
HTRF: A Technology Tailored for Drug Discovery - A Review of Theoretical Aspects and Recent Applications
-
Degorce F., Card A., Soh S., et al. HTRF: A Technology Tailored for Drug Discovery - a Review of Theoretical Aspects and Recent Applications. Curr. Chem. Genom. 2009 ; 3: 22-32
-
(2009)
Curr. Chem. Genom
, vol.3
, pp. 22-32
-
-
Degorce, F.1
Card, A.2
Soh, S.3
-
56
-
-
0035975882
-
Twenty-Five Years of Immobilized Metal Ion Affinity Chromatography: Past, Present and Future
-
Chaga G. S.. Twenty-Five Years of Immobilized Metal Ion Affinity Chromatography: Past, Present and Future. J. Biochem. Biophys. Meth. 2001 ; 49 (1-3). 313-334
-
(2001)
J. Biochem. Biophys. Meth
, vol.49
, Issue.13
, pp. 313-334
-
-
Chaga, G.S.1
-
57
-
-
54849418389
-
High-Throughput T7 LIC Vector for Introducing C-Terminal Poly-Histidine Tags with Variable Lengths without Extra Sequences
-
Lee J., Kim S.-H.. High-Throughput T7 LIC Vector for Introducing C-Terminal Poly-Histidine Tags with Variable Lengths without Extra Sequences. Protein Expr. Purif. 2009 ; 63 (1). 58-61
-
(2009)
Protein Expr. Purif
, vol.63
, Issue.1
, pp. 58-61
-
-
Lee, J.1
Kim, S.-H.2
-
58
-
-
0023806075
-
Single-Step Purification of Polypeptides Expressed in Escherichia coli as Fusions with Glutathione S-Transferase
-
Smith D., Johnson K.. Single-Step Purification of Polypeptides Expressed in Escherichia coli as Fusions with Glutathione S-Transferase. Gene. 1988 ; 67 (1). 31-40
-
(1988)
Gene
, vol.67
, Issue.1
, pp. 31-40
-
-
Smith, D.1
Johnson, K.2
-
59
-
-
0023680201
-
Vectors That Facilitate the Expression and Purification of Foreign Peptides in Escherichia coli by Fusion to Maltose-Binding Protein
-
di Guan C., Li P., Riggs P., et al. Vectors That Facilitate the Expression and Purification of Foreign Peptides in Escherichia coli by Fusion to Maltose-Binding Protein. Gene. 1988 ; 67 (1). 21-30
-
(1988)
Gene
, vol.67
, Issue.1
, pp. 21-30
-
-
Di Guan, C.1
Li, P.2
Riggs, P.3
-
60
-
-
0035975859
-
The FLAG Peptide, a Versatile Fusion Tag for the Purification of Recombinant Proteins
-
Einhauer A., Jungbauer A.. The FLAG Peptide, a Versatile Fusion Tag for the Purification of Recombinant Proteins. J. Biochem. Biophys. Meth. 2001 ; 49 (1-3). 455-465
-
(2001)
J. Biochem. Biophys. Meth
, vol.49
, Issue.13
, pp. 455-465
-
-
Einhauer, A.1
Jungbauer, A.2
-
61
-
-
15744372778
-
Comparison of Affinity Tags for Protein Purification
-
Lichty J., Malecki J., Agnew H., et al. Comparison of Affinity Tags for Protein Purification. Protein Expr. Purif. 2005 ; 41 (1). 98-105
-
(2005)
Protein Expr. Purif
, vol.41
, Issue.1
, pp. 98-105
-
-
Lichty, J.1
Malecki, J.2
Agnew, H.3
-
62
-
-
0027499708
-
The Random Peptide Library-Assisted Engineering of a C-Terminal Affinity Peptide, Useful for the Detection and Purification of a Functional Ig Fv Fragment
-
Schmidt T., Skerra A.. The Random Peptide Library-Assisted Engineering of a C-Terminal Affinity Peptide, Useful for the Detection and Purification of a Functional Ig Fv Fragment. Prot. Engin. 1993 ; 6 (1). 109-122
-
(1993)
Prot. Engin
, vol.6
, Issue.1
, pp. 109-122
-
-
Schmidt, T.1
Skerra, A.2
-
63
-
-
0036129945
-
Improved Affinity of Engineered Streptavidin for the Strep-Tag II Peptide Is Due to a Fixed Open Conformation of the Lid-Like Loop at the Binding Site
-
Korndorfer I. P.. Improved Affinity of Engineered Streptavidin for the Strep-Tag II Peptide Is Due to a Fixed Open Conformation of the Lid-Like Loop at the Binding Site. Protein Sci. 2002 ; 11: 883-893
-
(2002)
Protein Sci
, vol.11
, pp. 883-893
-
-
Korndorfer, I.P.1
-
64
-
-
0035543198
-
One-Step Purification of Recombinant Proteins Using a Nanomolar-Affinity Streptavidin-Binding Peptide, the SBP-Tag
-
Keefe A., Wilson D., Seelig B., et al. One-Step Purification of Recombinant Proteins Using a Nanomolar-Affinity Streptavidin-Binding Peptide, the SBP-Tag. Protein Expr. Purif. 2001 ; 23 (3). 440-446
-
(2001)
Protein Expr. Purif
, vol.23
, Issue.3
, pp. 440-446
-
-
Keefe, A.1
Wilson, D.2
Seelig, B.3
-
65
-
-
84880469170
-
Structure-Guided Design of an Engineered Streptavidin with Reusability to Purify Streptavidin-Binding Peptide Tagged Proteins or Biotinylated Proteins
-
Wu S.-C., Wong S.-L.. Structure-Guided Design of an Engineered Streptavidin with Reusability to Purify Streptavidin-Binding Peptide Tagged Proteins or Biotinylated Proteins. PloS One. 2013 ; 8 (7). e69530
-
(2013)
PloS One
, vol.8
, Issue.7
, pp. 69530
-
-
Wu, S.-C.1
Wong, S.-L.2
-
66
-
-
79952198939
-
Tag Removal by Site-Specific Cleavage of Recombinant Fusion Proteins
-
Charlton A., Zachariou M.. Tag Removal by Site-Specific Cleavage of Recombinant Fusion Proteins. Meth. Molec. Biol. 2011 ; 681: 349-367
-
(2011)
Meth. Molec. Biol
, vol.681
, pp. 349-367
-
-
Charlton, A.1
Zachariou, M.2
-
67
-
-
29344475982
-
Comparison of SUMO Fusion Technology with Traditional Gene Fusion Systems: Enhanced Expression and Solubility with SUMO
-
Marblestone J., Edavettal S., Lim Y., et al. Comparison of SUMO Fusion Technology with Traditional Gene Fusion Systems: Enhanced Expression and Solubility with SUMO. Protein Sci. 2006 ; 15 (1). 182-189
-
(2006)
Protein Sci
, vol.15
, Issue.1
, pp. 182-189
-
-
Marblestone, J.1
Edavettal, S.2
Lim, Y.3
-
68
-
-
0030940098
-
Interleukin-6: Structure-Function Relationships
-
Simpson R., Hammacher A., Smith D., et al. Interleukin-6: Structure-Function Relationships. Protein Sci. 1997 ; 6 (5). 929-955
-
(1997)
Protein Sci
, vol.6
, Issue.5
, pp. 929-955
-
-
Simpson, R.1
Hammacher, A.2
Smith, D.3
-
69
-
-
84872824121
-
Recombinant Production of Human Interleukin 6 in Escherichia coli
-
Nausch H., Huckauf J., Koslowski R., et al. Recombinant Production of Human Interleukin 6 in Escherichia coli. PloS One. 2013 ; 8 ( 1 ):
-
(2013)
PloS One
, vol.8
, Issue.1
-
-
Nausch, H.1
Huckauf, J.2
Koslowski, R.3
-
70
-
-
66949126546
-
Strategies for Successful Recombinant Expression of Disulfide Bond-Dependent Proteins in Escherichia coli
-
de Marco A.. Strategies for Successful Recombinant Expression of Disulfide Bond-Dependent Proteins in Escherichia coli. Microb. Cell Fact. 2009 ; 8: 26
-
(2009)
Microb. Cell Fact
, vol.8
, pp. 26
-
-
De Marco, A.1
-
71
-
-
33749164003
-
Formation of Active Inclusion Bodies in the Periplasm of Escherichia coli
-
Arié J.-P., Miot M., Sassoon N., et al. Formation of Active Inclusion Bodies in the Periplasm of Escherichia coli. Molec. Microbiol. 2006 ; 62 (2). 427-437
-
(2006)
Molec. Microbiol
, vol.62
, Issue.2
, pp. 427-437
-
-
Arié, J.-P.1
Miot, M.2
Sassoon, N.3
-
72
-
-
33845913565
-
A Simple Vector System to Improve Performance and Utilisation of Recombinant Antibodies
-
Martin C., Rojas G., Mitchell J., et al. A Simple Vector System to Improve Performance and Utilisation of Recombinant Antibodies. BMC Biotech. 2006 ; 6: 46
-
(2006)
BMC Biotech
, vol.6
, pp. 46
-
-
Martin, C.1
Rojas, G.2
Mitchell, J.3
-
74
-
-
84879130126
-
Advances in Recombinant Protein Expression for Use in Pharmaceutical Research
-
Assenberg R., Wan P., Geisse S., et al. Advances in Recombinant Protein Expression for Use in Pharmaceutical Research. Curr. Opin. Struct. Biol. 2013 ; 23 (3). 393-402
-
(2013)
Curr. Opin. Struct. Biol
, vol.23
, Issue.3
, pp. 393-402
-
-
Assenberg, R.1
Wan, P.2
Geisse, S.3
-
75
-
-
74149085088
-
Silkworm Expression System as a Platform Technology in Life Science
-
Kato T., Kajikawa M., Maenaka K., et al. Silkworm Expression System as a Platform Technology in Life Science. Appl. Microbiol. Biotechnol. 2010 ; 85 (3). 459-470
-
(2010)
Appl. Microbiol. Biotechnol
, vol.85
, Issue.3
, pp. 459-470
-
-
Kato, T.1
Kajikawa, M.2
Maenaka, K.3
-
76
-
-
33748742271
-
Protein N-Glycosylation in the Baculovirus-Insect Cell Expression System and Engineering of Insect Cells to Produce "mammalianized" Recombinant Glycoproteins
-
Harrison R. L., Jarvis D. L.. Protein N-Glycosylation in the Baculovirus-Insect Cell Expression System and Engineering of Insect Cells to Produce "Mammalianized" Recombinant Glycoproteins. Adv. Virus Res. 2006 ; 68: 159-191
-
(2006)
Adv. Virus Res
, vol.68
, pp. 159-191
-
-
Harrison, R.L.1
Jarvis, D.L.2
-
77
-
-
84858994151
-
A Comparative Study on the Expression, Purification and Functional Characterization of Human Adiponectin in Pichia pastoris and Escherichia coli
-
Rothan H., Teh S., Haron K., et al. A Comparative Study on the Expression, Purification and Functional Characterization of Human Adiponectin in Pichia pastoris and Escherichia coli. Intl. J. Molec. Sci. 2012 ; 13 (3). 3549-3562
-
(2012)
Intl. J. Molec. Sci
, vol.13
, Issue.3
, pp. 3549-3562
-
-
Rothan, H.1
Teh, S.2
Haron, K.3
-
78
-
-
84883896774
-
High Level Expression, Efficient Purification and Bioactivity Assay of Recombinant Human Platelet-Derived Growth Factor AA Dimer (PDGF-AA) from Methylotrophic Yeast
-
Li H., Hui X., Yang S., et al. High Level Expression, Efficient Purification and Bioactivity Assay of Recombinant Human Platelet-Derived Growth Factor AA Dimer (PDGF-AA) from Methylotrophic Yeast. Pichia pastoris. Protein Expr. Purif. 2013 ; 91 (2). 221-227
-
(2013)
Pichia Pastoris. Protein Expr. Purif
, vol.91
, Issue.2
, pp. 221-227
-
-
Li, H.1
Hui, X.2
Yang, S.3
-
79
-
-
84884687383
-
Expression, Purification, and Biological Characterization of the Amino-Terminal Fragment of Urokinase in Pichia pastoris
-
Li J., Lin Y., Zhuang H., et al. Expression, Purification, and Biological Characterization of the Amino-Terminal Fragment of Urokinase in Pichia pastoris. J. Microbiol. Biotech. 2013 ; 23 (9). 1197-1205
-
(2013)
J. Microbiol. Biotech
, vol.23
, Issue.9
, pp. 1197-1205
-
-
Li, J.1
Lin, Y.2
Zhuang, H.3
-
80
-
-
84856790732
-
Recombinant Protein Expression in Pichia pastoris Strains with an Engineered Methanol Utilization Pathway
-
Krainer F., Dietzsch C., Hajek T., et al. Recombinant Protein Expression in Pichia pastoris Strains with an Engineered Methanol Utilization Pathway. Microb. Cell Fact. 2012 ; 11: 22
-
(2012)
Microb. Cell Fact
, vol.11
, pp. 22
-
-
Krainer, F.1
Dietzsch, C.2
Hajek, T.3
-
81
-
-
83155188271
-
Novel Yeast Bioassay for High-Throughput Screening of Matrix Metalloproteinase Inhibitors
-
Diehl B., Hoffmann T. M., Mueller N. C., et al. Novel Yeast Bioassay for High-Throughput Screening of Matrix Metalloproteinase Inhibitors. Appl. Environ. Microbiol. 2011 ; 77: 8573-8577
-
(2011)
Appl. Environ. Microbiol
, vol.77
, pp. 8573-8577
-
-
Diehl, B.1
Hoffmann, T.M.2
Mueller, N.C.3
-
82
-
-
84879446443
-
High Level Transient Production of Recombinant Antibodies and Antibody Fusion Proteins in HEK293 Cells
-
Jäger V., Büssow K., Wagner A., et al. High Level Transient Production of Recombinant Antibodies and Antibody Fusion Proteins in HEK293 Cells. BMC Biotech. 2013 ; 13 (1). 52
-
(2013)
BMC Biotech
, vol.13
, Issue.1
, pp. 52
-
-
Jäger, V.1
Büssow, K.2
Wagner, A.3
-
83
-
-
84880413630
-
Multi-Host Expression System for Recombinant Production of Challenging Proteins
-
Meyer S., Lorenz C., Baser B., et al. Multi-Host Expression System for Recombinant Production of Challenging Proteins. PloS One. 2013 ; 8 (7). e68674
-
(2013)
PloS One
, vol.8
, Issue.7
, pp. 68674
-
-
Meyer, S.1
Lorenz, C.2
Baser, B.3
-
84
-
-
33846581487
-
Multiplexed Expression and Screening for Recombinant Protein Production in Mammalian Cells
-
Chapple S., Crofts A., Shadbolt S., et al. Multiplexed Expression and Screening for Recombinant Protein Production in Mammalian Cells. BMC Biotech. 2006 ; 6: 49
-
(2006)
BMC Biotech
, vol.6
, pp. 49
-
-
Chapple, S.1
Crofts, A.2
Shadbolt, S.3
-
85
-
-
79959935033
-
Automation of Large Scale Transient Protein Expression in Mammalian Cells
-
Zhao Y., Bishop B., Clay J., et al. Automation of Large Scale Transient Protein Expression in Mammalian Cells. J. Struct. Biol. 2011 ; 175 (2). 209-215
-
(2011)
J. Struct. Biol
, vol.175
, Issue.2
, pp. 209-215
-
-
Zhao, Y.1
Bishop, B.2
Clay, J.3
-
86
-
-
60549102676
-
Autotaxin Inhibition: Challenges and Progress toward Novel Anti-Cancer Agents
-
Parrill A. L., Baker D. L.. Autotaxin Inhibition: Challenges and Progress toward Novel Anti-Cancer Agents. Anticancer Agents Med. Chem. 2008 ; 8 (8). 917-923
-
(2008)
Anticancer Agents Med. Chem
, vol.8
, Issue.8
, pp. 917-923
-
-
Parrill, A.L.1
Baker, D.L.2
-
87
-
-
77956543889
-
Large Scale Purification and Characterization of Recombinant Human Autotaxin/Lysophospholipase D from Mammalian Cells
-
Song Y., Dilger E., Bell J., et al. Large Scale Purification and Characterization of Recombinant Human Autotaxin/Lysophospholipase D from Mammalian Cells. BMB Rep. 2010 ; 43 (8). 541-546
-
(2010)
BMB Rep
, vol.43
, Issue.8
, pp. 541-546
-
-
Song, Y.1
Dilger, E.2
Bell, J.3
-
88
-
-
79551646019
-
Crystal Structure of Autotaxin and Insight into GPCR Activation by Lipid Mediators
-
Nishimasu H., Okudaira S., Hama K., et al. Crystal Structure of Autotaxin and Insight into GPCR Activation by Lipid Mediators. Nat. Struct. Molec. Biol. 2011 ; 18 (2). 205-212
-
(2011)
Nat. Struct. Molec. Biol
, vol.18
, Issue.2
, pp. 205-212
-
-
Nishimasu, H.1
Okudaira, S.2
Hama, K.3
-
89
-
-
77953778656
-
A Novel Autotaxin Inhibitor Reduces Lysophosphatidic Acid Levels in Plasma and the Site of Inflammation
-
Gierse J., Thorarensen A., Beltey K., et al. A Novel Autotaxin Inhibitor Reduces Lysophosphatidic Acid Levels in Plasma and the Site of Inflammation. J. Pharm. Exper. Therap. 2010 ; 334 (1). 310-317
-
(2010)
J. Pharm. Exper. Therap
, vol.334
, Issue.1
, pp. 310-317
-
-
Gierse, J.1
Thorarensen, A.2
Beltey, K.3
-
90
-
-
84855974397
-
Recombinant Protein Production in the Eukaryotic Protozoan Parasite Leishmania tarentolae: A Review
-
Niimi T.. Recombinant Protein Production in the Eukaryotic Protozoan Parasite Leishmania tarentolae: A Review. Meth. Molec. Biol. 2012 ; 824: 307-315
-
(2012)
Meth. Molec. Biol
, vol.824
, pp. 307-315
-
-
Niimi, T.1
-
91
-
-
18644383997
-
Non-Pathogenic Trypanosomatid Protozoa as a Platform for Protein Research and Production
-
Breitling R., Klingner S., Callewaert N., et al. Non-Pathogenic Trypanosomatid Protozoa as a Platform for Protein Research and Production. Protein Expr. Purif. 2002 ; 25 (2). 209-218
-
(2002)
Protein Expr. Purif
, vol.25
, Issue.2
, pp. 209-218
-
-
Breitling, R.1
Klingner, S.2
Callewaert, N.3
-
92
-
-
68349158805
-
The Production of Recombinant Human Laminin-332 in a Leishmania tarentolae Expression System
-
Phan H. P., Sugino M., Niimi T.. The Production of Recombinant Human Laminin-332 in a Leishmania tarentolae Expression System. Protein Expr. Purif. 2009 ; 68 (1). 79-84
-
(2009)
Protein Expr. Purif
, vol.68
, Issue.1
, pp. 79-84
-
-
Phan, H.P.1
Sugino, M.2
Niimi, T.3
-
93
-
-
77955449967
-
Purification and Crystallization of Human Cu/Zn Superoxide Dismutase Recombinantly Produced in the Protozoan
-
Gazdag E., Cirstea I., Breitling R., et al. Purification and Crystallization of Human Cu/Zn Superoxide Dismutase Recombinantly Produced in the Protozoan. Leishmania tarentolae. Acta Crystallograph. F. 2010 ; 66 (Pt. 8). 871-877
-
(2010)
Leishmania Tarentolae. Acta Crystallograph. F
, vol.66
, Issue.PART. 8
, pp. 871-877
-
-
Gazdag, E.1
Cirstea, I.2
Breitling, R.3
-
94
-
-
84880028167
-
Expression of a Truncated Hepatitis e Virus Capsid Protein in the Protozoan Organism Leishmania tarentolae and Its Application in a Serological Assay
-
Baechlein C., Meemken D., Pezzoni G., et al. Expression of a Truncated Hepatitis E Virus Capsid Protein in the Protozoan Organism Leishmania tarentolae and Its Application in a Serological Assay. J. Virol. Meth. 2013 ; 193 (1). 238-243
-
(2013)
J. Virol. Meth
, vol.193
, Issue.1
, pp. 238-243
-
-
Baechlein, C.1
Meemken, D.2
Pezzoni, G.3
-
95
-
-
84878892481
-
Cell-Free Translation of Peptides and Proteins: From High Throughput Screening to Clinical Production
-
Murray C. J., Baliga R.. Cell-Free Translation of Peptides and Proteins: From High Throughput Screening to Clinical Production. Curr. Opin. Chem. Biol. 2013 ; 17 (3). 420-426
-
(2013)
Curr. Opin. Chem. Biol
, vol.17
, Issue.3
, pp. 420-426
-
-
Murray, C.J.1
Baliga, R.2
-
96
-
-
84888046697
-
Cell-Free Protein Expression Based on Extracts from CHO Cells
-
Brödel A., Sonnabend A., Kubick S.. Cell-Free Protein Expression Based on Extracts from CHO Cells. Biotechnol. Bioengin. 2013 ; 111: 25-36
-
(2013)
Biotechnol. Bioengin
, vol.111
, pp. 25-36
-
-
Brödel, A.1
Sonnabend, A.2
Kubick, S.3
-
97
-
-
84884644197
-
Are GPCRs Still a Source of New Targets?
-
Garland S. L.. Are GPCRs Still a Source of New Targets?. J. Biomol. Screen. 2013 ; 18 (9). 947-966
-
(2013)
J. Biomol. Screen
, vol.18
, Issue.9
, pp. 947-966
-
-
Garland, S.L.1
-
99
-
-
83755163795
-
Heterologous Expression of Membrane Proteins: Choosing the Appropriate Host
-
Bernaudat F., Frelet-Barrand A., Pochon N., et al. Heterologous Expression of Membrane Proteins: Choosing the Appropriate Host. PloS One. 2011 ; 6 ( 12 ):
-
(2011)
PloS One
, vol.6
, Issue.12
-
-
Bernaudat, F.1
Frelet-Barrand, A.2
Pochon, N.3
-
100
-
-
0026704014
-
Solubilization and Functional Reconstitution of Biomembrane Components
-
Silvius J. R.. Solubilization and Functional Reconstitution of Biomembrane Components. Ann. Rev. Biophys. Biomol. Struct. 1992 ; 21: 323-348
-
(1992)
Ann. Rev. Biophys. Biomol. Struct
, vol.21
, pp. 323-348
-
-
Silvius, J.R.1
-
101
-
-
0034707086
-
Interaction of Membrane Proteins and Opioids with Solubilizing Detergents
-
le Maire M., Champeil P., Moller J. V.. Interaction of Membrane Proteins and Opioids with Solubilizing Detergents. Biochim. Biophys. Acta. 2000 ; 1508 (1-2). 86-111
-
(2000)
Biochim. Biophys. Acta
, vol.1508
, Issue.12
, pp. 86-111
-
-
Le Maire, M.1
Champeil, P.2
Moller, J.V.3
-
102
-
-
0034629489
-
Building a Thermostable Membrane Protein
-
Zhou Y., Bowie J. U.. Building a Thermostable Membrane Protein. J. Biol. Chem. 2000 ; 275 (10). 6975-6979
-
(2000)
J. Biol. Chem
, vol.275
, Issue.10
, pp. 6975-6979
-
-
Zhou, Y.1
Bowie, J.U.2
-
103
-
-
0026968989
-
Frontiers in HIV-1 Therapy: Fourth Conference of the NIAID National Cooperative Drug Discovery Groups-HIV
-
Sarver N., Black R. J., Bridges S., et al. Frontiers in HIV-1 Therapy: Fourth Conference of the NIAID National Cooperative Drug Discovery Groups-HIV. AIDS Res. Hum. Retroviruses. 1992 ; 8 (5). 659-667
-
(1992)
AIDS Res. Hum. Retroviruses
, vol.8
, Issue.5
, pp. 659-667
-
-
Sarver, N.1
Black, R.J.2
Bridges, S.3
-
104
-
-
0026452941
-
Cell Type-Specific Anti-Human Immunodeficiency Virus Type 1 Activity of the Transactivation Inhibitor Ro5-3335
-
Witvrouw M., Pauwels R., Vandamme A. M., et al. Cell Type-Specific Anti-Human Immunodeficiency Virus Type 1 Activity of the Transactivation Inhibitor Ro5-3335. Antimicrob. Agents Chemother. 1992 ; 36 (12). 2628-2633
-
(1992)
Antimicrob. Agents Chemother
, vol.36
, Issue.12
, pp. 2628-2633
-
-
Witvrouw, M.1
Pauwels, R.2
Vandamme, A.M.3
-
105
-
-
84863813096
-
Design of an Automated Enhanced-Throughput Platform for Functional Characterization of Positive Allosteric Modulator-Induced Leftward Shifts in Apparent Agonist Potency in Vitro
-
Hendricson A., Matchett M., Ferrante M., et al. Design of an Automated Enhanced-Throughput Platform for Functional Characterization of Positive Allosteric Modulator-Induced Leftward Shifts in Apparent Agonist Potency in Vitro. J. Lab. Autom. 2012 ; 17 (2). 104-115
-
(2012)
J. Lab. Autom
, vol.17
, Issue.2
, pp. 104-115
-
-
Hendricson, A.1
Matchett, M.2
Ferrante, M.3
-
106
-
-
84867246771
-
Development of a High-Throughput Calcium Flux Assay for Identification of All Ligand Types including Positive, Negative, and Silent Allosteric Modulators for G Protein-Coupled Receptors
-
Noblin D. J., Bertekap R. L., Burford N. T., et al. Development of a High-Throughput Calcium Flux Assay for Identification of All Ligand Types including Positive, Negative, and Silent Allosteric Modulators for G Protein-Coupled Receptors. Assay Drug Dev. Technol. 2012 ; 10 (5). 457-467
-
(2012)
Assay Drug Dev. Technol
, vol.10
, Issue.5
, pp. 457-467
-
-
Noblin, D.J.1
Bertekap, R.L.2
Burford, N.T.3
-
107
-
-
0036209874
-
Endocytosis of G Protein-Coupled Receptors: Roles of G Protein-Coupled Receptor Kinases and Beta-Arrestin Proteins
-
Claing A., Laporte S., Caron M., et al. Endocytosis of G Protein-Coupled Receptors: Roles of G Protein-Coupled Receptor Kinases and Beta-Arrestin Proteins. Prog. Neurobiol. 2002 ; 66 (2). 61-79
-
(2002)
Prog. Neurobiol
, vol.66
, Issue.2
, pp. 61-79
-
-
Claing, A.1
Laporte, S.2
Caron, M.3
-
108
-
-
84866855674
-
Ubiquitination of G Protein-Coupled Receptors: Functional Implications and Drug Discovery
-
Dores M. R., Trejo J.. Ubiquitination of G Protein-Coupled Receptors: Functional Implications and Drug Discovery. Molec. Pharmacol. 2012 ; 82 (4). 563-570
-
(2012)
Molec. Pharmacol
, vol.82
, Issue.4
, pp. 563-570
-
-
Dores, M.R.1
Trejo, J.2
-
109
-
-
0030346309
-
Palmitoylation: A Post-Translational Modification That Regulates Signalling from G-Protein Coupled Receptors
-
Morello J. P., Bouvier M.. Palmitoylation: A Post-Translational Modification That Regulates Signalling from G-Protein Coupled Receptors. Biochem. Cell Biol. 1996 ; 74 (4). 449-457
-
(1996)
Biochem. Cell Biol
, vol.74
, Issue.4
, pp. 449-457
-
-
Morello, J.P.1
Bouvier, M.2
-
110
-
-
0032799753
-
Glycosylation of G-Protein-Coupled Receptors for Hormones Central to Normal Reproductive Functioning: Its Occurrence and Role
-
Wheatley M., Hawtin S. R.. Glycosylation of G-Protein-Coupled Receptors for Hormones Central to Normal Reproductive Functioning: Its Occurrence and Role. Hum. Reprod. Update. 1999 ; 5 (4). 356-364
-
(1999)
Hum. Reprod. Update
, vol.5
, Issue.4
, pp. 356-364
-
-
Wheatley, M.1
Hawtin, S.R.2
-
111
-
-
0029805551
-
Post-Translational Modifications in Insect Cells
-
Klenk H.. Post-Translational Modifications in Insect Cells. Cytotechnology. 1996 ; 20 (1-3). 139-144
-
(1996)
Cytotechnology
, vol.20
, Issue.13
, pp. 139-144
-
-
Klenk, H.1
-
112
-
-
0037007003
-
Co- and Posttranslational Modification of the Alpha(1B)-Adrenergic Receptor: Effects on Receptor Expression and Function
-
Bjorklof K., Lundstrom K., Abuin L., et al. Co- and Posttranslational Modification of the Alpha(1B)-Adrenergic Receptor: Effects on Receptor Expression and Function. Biochemistry. 2002 ; 41 (13). 4281-4291
-
(2002)
Biochemistry
, vol.41
, Issue.13
, pp. 4281-4291
-
-
Bjorklof, K.1
Lundstrom, K.2
Abuin, L.3
-
113
-
-
34848882182
-
Profiling of Membrane Protein Variants in a Baculovirus System by Coupling Cell-Surface Detection with Small-Scale Parallel Expression
-
Hanson M. A., Brooun A., Baker K. A., et al. Profiling of Membrane Protein Variants in a Baculovirus System by Coupling Cell-Surface Detection with Small-Scale Parallel Expression. Protein Expr. Purif. 2007 ; 56 (1). 85-92
-
(2007)
Protein Expr. Purif
, vol.56
, Issue.1
, pp. 85-92
-
-
Hanson, M.A.1
Brooun, A.2
Baker, K.A.3
-
114
-
-
67650376998
-
GPCR Expression Using Baculovirus-Infected Sf9 Cells
-
Aloia A. L., Glatz R. V., McMurchie E. J., et al. GPCR Expression Using Baculovirus-Infected Sf9 Cells. Meth. Molec. Biol. 2009 ; 552: 115-129
-
(2009)
Meth. Molec. Biol
, vol.552
, pp. 115-129
-
-
Aloia, A.L.1
Glatz, R.V.2
McMurchie, E.J.3
-
115
-
-
34250306407
-
Heterologous GPCR Expression: A Bottleneck to Obtaining Crystal Structures
-
McCusker E. C., Bane S. E., O'Malley M. A., et al. Heterologous GPCR Expression: A Bottleneck to Obtaining Crystal Structures. Biotechnol. Prog. 2007 ; 23 (3). 540-547
-
(2007)
Biotechnol. Prog
, vol.23
, Issue.3
, pp. 540-547
-
-
McCusker, E.C.1
Bane, S.E.2
O'Malley, M.A.3
-
116
-
-
79955033084
-
Evaluation of the Pichia pastoris Expression System for the Production of GPCRs for Structural Analysis
-
Asada H., Uemura T., Yurugi-Kobayashi T., et al. Evaluation of the Pichia pastoris Expression System for the Production of GPCRs for Structural Analysis. Microb. Cell Fact. 2011 ; 10: 24
-
(2011)
Microb. Cell Fact
, vol.10
, pp. 24
-
-
Asada, H.1
Uemura, T.2
Yurugi-Kobayashi, T.3
-
117
-
-
67650389233
-
BacMam: Versatile Gene Delivery Technology for GPCR Assays
-
Davenport E. A., Nuthulaganti P., Ames R. S.. BacMam: Versatile Gene Delivery Technology for GPCR Assays. Methods Mol. Biol. 2009 ; 552: 199-211
-
(2009)
Methods Mol. Biol
, vol.552
, pp. 199-211
-
-
Davenport, E.A.1
Nuthulaganti, P.2
Ames, R.S.3
-
118
-
-
34247533256
-
Implementation of BacMam Virus Gene Delivery Technology in a Drug Discovery Setting
-
Kost T. A., Condreay J. P., Ames R. S., et al. Implementation of BacMam Virus Gene Delivery Technology in a Drug Discovery Setting. Drug Discov. Today. 2007 ; 12 (9-10). 396-403
-
(2007)
Drug Discov. Today
, vol.12
, Issue.910
, pp. 396-403
-
-
Kost, T.A.1
Condreay, J.P.2
Ames, R.S.3
-
119
-
-
84878848170
-
Stabilizing Membrane Proteins through Protein Engineering
-
Scott D., Kummer L., Tremmel D., et al. Stabilizing Membrane Proteins through Protein Engineering. Curr. Opin. Chem. Biol. 2013 ; 17 (3). 427-435
-
(2013)
Curr. Opin. Chem. Biol
, vol.17
, Issue.3
, pp. 427-435
-
-
Scott, D.1
Kummer, L.2
Tremmel, D.3
-
120
-
-
70350749580
-
Transferability of Thermostabilizing Mutations between Beta-Adrenergic Receptors
-
Serrano-Vega M., Tate C.. Transferability of Thermostabilizing Mutations between Beta-Adrenergic Receptors. Molec. Memb. Biol. 2009 ; 26 (8). 385-396
-
(2009)
Molec. Memb. Biol
, vol.26
, Issue.8
, pp. 385-396
-
-
Serrano-Vega, M.1
Tate, C.2
-
121
-
-
84871918476
-
The GPCR Network: A Large-Scale Collaboration to Determine Human GPCR Structure and Function
-
Stevens R. C., Cherezov V., Katritch V., et al. The GPCR Network: A Large-Scale Collaboration to Determine Human GPCR Structure and Function. Nat. Rev. Drug Discov. 2013 ; 12 (1). 25-34
-
(2013)
Nat. Rev. Drug Discov
, vol.12
, Issue.1
, pp. 25-34
-
-
Stevens, R.C.1
Cherezov, V.2
Katritch, V.3
-
122
-
-
84881193006
-
Structure of the Human Glucagon Class B G-Protein-Coupled Receptor
-
Siu F. Y., He M., de Graaf C., et al. Structure of the Human Glucagon Class B G-Protein-Coupled Receptor. Nature. 2013 ; 499 (7459). 444-449
-
(2013)
Nature
, vol.499
, Issue.7459
, pp. 444-449
-
-
Siu, F.Y.1
He, M.2
De Graaf, C.3
-
123
-
-
84865994337
-
Molecular Basis for Negative Regulation of the Glucagon Receptor
-
Koth C. M., Murray J. M., Mukund S., et al. Molecular Basis for Negative Regulation of the Glucagon Receptor. Proc. Natl. Acad. Sci. USA. 2012 ; 109 (36). 14393-14398
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, Issue.36
, pp. 14393-14398
-
-
Koth, C.M.1
Murray, J.M.2
Mukund, S.3
-
124
-
-
78651411166
-
Structure of a Nanobody-Stabilized Active State of the Beta(2) Adrenoceptor
-
Rasmussen S. G., Choi H. J., Fung J. J., et al. Structure of a Nanobody-Stabilized Active State of the Beta(2) Adrenoceptor. Nature. 2011 ; 469 (7329). 175-180
-
(2011)
Nature
, vol.469
, Issue.7329
, pp. 175-180
-
-
Rasmussen, S.G.1
Choi, H.J.2
Fung, J.J.3
-
125
-
-
80051658642
-
Crystal Structure of the Beta2 Adrenergic Receptor-Gs Protein Complex
-
Rasmussen S. G., DeVree B. T., Zou Y., et al. Crystal Structure of the Beta2 Adrenergic Receptor-Gs Protein Complex. Nature. 2011 ; 477 (7366). 549-555
-
(2011)
Nature
, vol.477
, Issue.7366
, pp. 549-555
-
-
Rasmussen, S.G.1
Devree, B.T.2
Zou, Y.3
-
126
-
-
80052083563
-
Nanobody Stabilization of G Protein-Coupled Receptor Conformational States
-
Steyaert J., Kobilka B. K.. Nanobody Stabilization of G Protein-Coupled Receptor Conformational States. Curr. Opin. Struct. Biol. 2011 ; 21 (4). 567-572
-
(2011)
Curr. Opin. Struct. Biol
, vol.21
, Issue.4
, pp. 567-572
-
-
Steyaert, J.1
Kobilka, B.K.2
-
128
-
-
33847639732
-
Applications of Phospholipid Bilayer Nanodiscs in the Study of Membranes and Membrane Proteins
-
Nath A., Atkins W. M., Sligar S. G.. Applications of Phospholipid Bilayer Nanodiscs in the Study of Membranes and Membrane Proteins. Biochemistry. 2007 ; 46 (8). 2059-2069
-
(2007)
Biochemistry
, vol.46
, Issue.8
, pp. 2059-2069
-
-
Nath, A.1
Atkins, W.M.2
Sligar, S.G.3
-
129
-
-
1642382983
-
Directed Self-Assembly of Monodisperse Phospholipid Bilayer Nanodiscs with Controlled Size
-
Denisov I. G., Grinkova Y. V., Lazarides A. A., et al. Directed Self-Assembly of Monodisperse Phospholipid Bilayer Nanodiscs with Controlled Size. J. Am. Chem. Soc. 2004 ; 126 (11). 3477-3487
-
(2004)
J. Am. Chem. Soc
, vol.126
, Issue.11
, pp. 3477-3487
-
-
Denisov, I.G.1
Grinkova, Y.V.2
Lazarides, A.A.3
-
130
-
-
0043007514
-
Self-Assembly of Discoidal Phospholipid Bilayer Nanoparticles with Membrane Scaffold Proteins
-
Timothy H. B., Yelena V. G., Stephen G. S.. Self-Assembly of Discoidal Phospholipid Bilayer Nanoparticles with Membrane Scaffold Proteins. Nano. Lett. 2002 ; 2: 853-856
-
(2002)
Nano. Lett
, vol.2
, pp. 853-856
-
-
Timothy, H.B.1
Yelena, V.G.2
Stephen, G.S.3
-
131
-
-
53049089639
-
Direct and Potent Regulation of Gamma-Secretase by Its Lipid Microenvironment
-
Osenkowski P., Ye W., Wang R., et al. Direct and Potent Regulation of Gamma-Secretase by Its Lipid Microenvironment. J. Biol. Chem. 2008 ; 283 (33). 22529-22540
-
(2008)
J. Biol. Chem
, vol.283
, Issue.33
, pp. 22529-22540
-
-
Osenkowski, P.1
Ye, W.2
Wang, R.3
-
132
-
-
0036830410
-
Structural Genomics. Tapping DNA for Structures Produces a Trickle
-
Service R. F.. Structural Genomics. Tapping DNA for Structures Produces a Trickle. Science. 2002 ; 298 (5595). 948-950
-
(2002)
Science
, vol.298
, Issue.5595
, pp. 948-950
-
-
Service, R.F.1
|