-
1
-
-
2342443000
-
Nobel lecture. Worms, life and death
-
Horvitz H.R. Nobel lecture. Worms, life and death. Biosci Rep 2003, 23(5-6):239-303.
-
(2003)
Biosci Rep
, vol.23
, Issue.5-6
, pp. 239-303
-
-
Horvitz, H.R.1
-
2
-
-
0009530192
-
Human ICE/CED-3 protease nomenclature [Letter]
-
Alnemri E., Livingston D., Nicholson D., Salvesen G., Thornberry N., Wong W. Human ICE/CED-3 protease nomenclature [Letter]. Cell 1996, 87:171.
-
(1996)
Cell
, vol.87
, pp. 171
-
-
Alnemri, E.1
Livingston, D.2
Nicholson, D.3
Salvesen, G.4
Thornberry, N.5
Wong, W.6
-
3
-
-
0033179760
-
BCL-2 family members and the mitochondria in apoptosis
-
Gross A., McDonnell J.M., Korsmeyer S.J. BCL-2 family members and the mitochondria in apoptosis. Genes Dev 1999, 13(15):1899-1911.
-
(1999)
Genes Dev
, vol.13
, Issue.15
, pp. 1899-1911
-
-
Gross, A.1
McDonnell, J.M.2
Korsmeyer, S.J.3
-
4
-
-
0030849093
-
A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis
-
Thornberry N., Rano T., Peterson E., Rasper D., Timkey T., Garcia-Calvo M. A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis. J Biol Chem 1997, 272(29):17907-17911.
-
(1997)
J Biol Chem
, vol.272
, Issue.29
, pp. 17907-17911
-
-
Thornberry, N.1
Rano, T.2
Peterson, E.3
Rasper, D.4
Timkey, T.5
Garcia-Calvo, M.6
-
5
-
-
0030881603
-
Biochemical characteristics of caspases-3, -6, -7, and -8
-
Stennicke H.R., Salvesen G.S. Biochemical characteristics of caspases-3, -6, -7, and -8. J Biol Chem 1997, 272(41):25719-25723.
-
(1997)
J Biol Chem
, vol.272
, Issue.41
, pp. 25719-25723
-
-
Stennicke, H.R.1
Salvesen, G.S.2
-
6
-
-
0030849093
-
A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis
-
Thornberry N.A., Rano T.A., Peterson E.P., Rasper D.M., Timkey T., Garcia-Calvo M. A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis. J Biol Chem 1997, 272(29):17907-17911.
-
(1997)
J Biol Chem
, vol.272
, Issue.29
, pp. 17907-17911
-
-
Thornberry, N.A.1
Rano, T.A.2
Peterson, E.P.3
Rasper, D.M.4
Timkey, T.5
Garcia-Calvo, M.6
-
7
-
-
0030948457
-
Substrate specificities of caspase family proteases
-
Talanian R.V., Quinlan C., Trautz S., Hackett M.C., Mankovich J.A., Banach D. Substrate specificities of caspase family proteases. J Biol Chem 1997, 272(15):9677-9682.
-
(1997)
J Biol Chem
, vol.272
, Issue.15
, pp. 9677-9682
-
-
Talanian, R.V.1
Quinlan, C.2
Trautz, S.3
Hackett, M.C.4
Mankovich, J.A.5
Banach, D.6
-
8
-
-
0034283578
-
Internally quenched fluorescent peptide substrates disclose the subsite preferences of human caspases 1, 3, 6, 7 and 8
-
Stennicke H.R., Renatus M., Meldal M., Salvesen G.S. Internally quenched fluorescent peptide substrates disclose the subsite preferences of human caspases 1, 3, 6, 7 and 8. Biochem J 2000, 350(Pt 2):563-568.
-
(2000)
Biochem J
, vol.350
, Issue.PART 2
, pp. 563-568
-
-
Stennicke, H.R.1
Renatus, M.2
Meldal, M.3
Salvesen, G.S.4
-
9
-
-
0029114596
-
Two tumour necrosis factor receptors: structure and function
-
Vandenabeele P., Declercq W., Beyaert R., Fiers W. Two tumour necrosis factor receptors: structure and function. Trends Cell Biol 1995, 5(10):392-399.
-
(1995)
Trends Cell Biol
, vol.5
, Issue.10
, pp. 392-399
-
-
Vandenabeele, P.1
Declercq, W.2
Beyaert, R.3
Fiers, W.4
-
10
-
-
15844412409
-
FLICE: a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex
-
Muzio M., Chinnaiyan A., Kischkel F., O'Rourke K., Shevchenko A., Ni J. FLICE: a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex. Cell 1996, 85(6):817-827.
-
(1996)
Cell
, vol.85
, Issue.6
, pp. 817-827
-
-
Muzio, M.1
Chinnaiyan, A.2
Kischkel, F.3
O'Rourke, K.4
Shevchenko, A.5
Ni, J.6
-
11
-
-
0030011398
-
Involvement of MACH: a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death
-
Boldin M.P., Goncharov T.M., Goltsev Y.V., Wallach D. Involvement of MACH: a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death. Cell 1996, 85(6):803-815.
-
(1996)
Cell
, vol.85
, Issue.6
, pp. 803-815
-
-
Boldin, M.P.1
Goncharov, T.M.2
Goltsev, Y.V.3
Wallach, D.4
-
12
-
-
0026729623
-
The biology and pathology of programmed cell death (apoptosis)
-
Anilkumar T.V., Sarraf C.E., Alison M.R. The biology and pathology of programmed cell death (apoptosis). Vet Hum Toxicol 1992, 34(3):251-254.
-
(1992)
Vet Hum Toxicol
, vol.34
, Issue.3
, pp. 251-254
-
-
Anilkumar, T.V.1
Sarraf, C.E.2
Alison, M.R.3
-
13
-
-
0034615555
-
Caspases - controlling intracellular signals by protease zymogen activation
-
Stennicke H.R., Salvesen G.S. Caspases - controlling intracellular signals by protease zymogen activation. Biochim Biophys Acta 2000, 1477(1-2):299-306.
-
(2000)
Biochim Biophys Acta
, vol.1477
, Issue.1-2
, pp. 299-306
-
-
Stennicke, H.R.1
Salvesen, G.S.2
-
14
-
-
0032143986
-
Targeted disruption of the mouse caspase 8 gene ablates cell death induction by the TNF receptors: Fas/Apo1, and DR3 and is lethal prenatally
-
Varfolomeev E.E., Schuchmann M., Luria V., Chiannilkulchai N., Beckmann J.S., Mett I.L. Targeted disruption of the mouse caspase 8 gene ablates cell death induction by the TNF receptors: Fas/Apo1, and DR3 and is lethal prenatally. Immunity 1998, 9(2):267-276.
-
(1998)
Immunity
, vol.9
, Issue.2
, pp. 267-276
-
-
Varfolomeev, E.E.1
Schuchmann, M.2
Luria, V.3
Chiannilkulchai, N.4
Beckmann, J.S.5
Mett, I.L.6
-
15
-
-
18544383460
-
Pleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency
-
Chun H.J., Zheng L., Ahmad M., Wang J., Speirs C.K., Siegel R.M. Pleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency. Nature 2002, 419(6905):395-399.
-
(2002)
Nature
, vol.419
, Issue.6905
, pp. 395-399
-
-
Chun, H.J.1
Zheng, L.2
Ahmad, M.3
Wang, J.4
Speirs, C.K.5
Siegel, R.M.6
-
16
-
-
0032482169
-
Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor
-
Vercammen D., Beyaert R., Denecker G., Goossens V., Van Loo G., Declercq W. Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor. J Exp Med 1998, 187(9):1477-1485.
-
(1998)
J Exp Med
, vol.187
, Issue.9
, pp. 1477-1485
-
-
Vercammen, D.1
Beyaert, R.2
Denecker, G.3
Goossens, V.4
Van Loo, G.5
Declercq, W.6
-
17
-
-
42249102086
-
Identification of RIP1 kinase as a specific cellular target of necrostatins
-
Degterev A., Hitomi J., Germscheid M., Ch'en I.L., Korkina O., Teng X. Identification of RIP1 kinase as a specific cellular target of necrostatins. Nat Chem Biol 2008, 4(5):313-321.
-
(2008)
Nat Chem Biol
, vol.4
, Issue.5
, pp. 313-321
-
-
Degterev, A.1
Hitomi, J.2
Germscheid, M.3
Ch'en, I.L.4
Korkina, O.5
Teng, X.6
-
18
-
-
80053580530
-
RIPK-dependent necrosis and its regulation by caspases: a mystery in five acts
-
Green D.R., Oberst A., Dillon C.P., Weinlich R., Salvesen G.S. RIPK-dependent necrosis and its regulation by caspases: a mystery in five acts. Mol Cell 2011, 44(1):9-16.
-
(2011)
Mol Cell
, vol.44
, Issue.1
, pp. 9-16
-
-
Green, D.R.1
Oberst, A.2
Dillon, C.P.3
Weinlich, R.4
Salvesen, G.S.5
-
19
-
-
82455212812
-
'Necrosome'-induced inflammation: must cells die for it?
-
Wallach D., Kovalenko A., Kang T.B. 'Necrosome'-induced inflammation: must cells die for it?. Trends Immunol 2011, 32(11):505-509.
-
(2011)
Trends Immunol
, vol.32
, Issue.11
, pp. 505-509
-
-
Wallach, D.1
Kovalenko, A.2
Kang, T.B.3
-
20
-
-
79960922705
-
CIAPs block ripoptosome formation: a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms
-
Feoktistova M., Geserick P., Kellert B., Dimitrova D.P., Langlais C., Hupe M. cIAPs block ripoptosome formation: a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms. Mol Cell 2011, 43(3):449-463.
-
(2011)
Mol Cell
, vol.43
, Issue.3
, pp. 449-463
-
-
Feoktistova, M.1
Geserick, P.2
Kellert, B.3
Dimitrova, D.P.4
Langlais, C.5
Hupe, M.6
-
21
-
-
79960921946
-
The ripoptosome: a signaling platform that assembles in response to genotoxic stress and loss of IAPs
-
Tenev T., Bianchi K., Darding M., Broemer M., Langlais C., Wallberg F. The ripoptosome: a signaling platform that assembles in response to genotoxic stress and loss of IAPs. Mol Cell 2011, 43(3):432-448.
-
(2011)
Mol Cell
, vol.43
, Issue.3
, pp. 432-448
-
-
Tenev, T.1
Bianchi, K.2
Darding, M.3
Broemer, M.4
Langlais, C.5
Wallberg, F.6
-
22
-
-
69249100500
-
Human caspases: activation, specificity, and regulation
-
Pop C., Salvesen G.S. Human caspases: activation, specificity, and regulation. J Biol Chem 2009, 284(33):21777-21781.
-
(2009)
J Biol Chem
, vol.284
, Issue.33
, pp. 21777-21781
-
-
Pop, C.1
Salvesen, G.S.2
-
24
-
-
77953896432
-
Cell signaling by receptor tyrosine kinases
-
Lemmon M.A., Schlessinger J. Cell signaling by receptor tyrosine kinases. Cell 2010, 141(7):1117-1134.
-
(2010)
Cell
, vol.141
, Issue.7
, pp. 1117-1134
-
-
Lemmon, M.A.1
Schlessinger, J.2
-
25
-
-
0032579490
-
An induced proximity model for caspase-8 activation
-
Muzio M., Stockwell B.R., Stennicke H.R., Salvesen G.S., Dixit V.M. An induced proximity model for caspase-8 activation. J Biol Chem 1998, 273(5):2926-2930.
-
(1998)
J Biol Chem
, vol.273
, Issue.5
, pp. 2926-2930
-
-
Muzio, M.1
Stockwell, B.R.2
Stennicke, H.R.3
Salvesen, G.S.4
Dixit, V.M.5
-
26
-
-
0037291871
-
A unified model for apical caspase activation
-
Boatright K.M., Renatus M., Scott F.L., Sperandio S., Shin H., Pedersen I.M. A unified model for apical caspase activation. Mol Cell 2003, 11(2):529-541.
-
(2003)
Mol Cell
, vol.11
, Issue.2
, pp. 529-541
-
-
Boatright, K.M.1
Renatus, M.2
Scott, F.L.3
Sperandio, S.4
Shin, H.5
Pedersen, I.M.6
-
27
-
-
34247345833
-
The apoptosome: signalling platform of cell death
-
Riedl S.J., Salvesen G.S. The apoptosome: signalling platform of cell death. Nat Rev Mol Cell Biol 2007, 8(5):405-413.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, Issue.5
, pp. 405-413
-
-
Riedl, S.J.1
Salvesen, G.S.2
-
28
-
-
0037291890
-
Insights into the regulatory mechanism for caspase-8 activation
-
Donepudi M., Mac Sweeney A., Briand C., Grütter M.G. Insights into the regulatory mechanism for caspase-8 activation. Mol Cell 2003, 11:543-549.
-
(2003)
Mol Cell
, vol.11
, pp. 543-549
-
-
Donepudi, M.1
Mac Sweeney, A.2
Briand, C.3
Grütter, M.G.4
-
29
-
-
0035807966
-
Dimer formation drives the activation of the cell death protease caspase 9
-
Renatus M., Stennicke H.R., Scott F.L., Liddington R.C., Salvesen G.S. Dimer formation drives the activation of the cell death protease caspase 9. Proc Natl Acad Sci U S A 2001, 98:14250-14255.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 14250-14255
-
-
Renatus, M.1
Stennicke, H.R.2
Scott, F.L.3
Liddington, R.C.4
Salvesen, G.S.5
-
30
-
-
68349154339
-
Reconstitution of the death-inducing signaling complex reveals a substrate switch that determines CD95-mediated death or survival
-
Hughes M.A., Harper N., Butterworth M., Cain K., Cohen G.M., MacFarlane M. Reconstitution of the death-inducing signaling complex reveals a substrate switch that determines CD95-mediated death or survival. Mol Cell 2009, 35(3):265-279.
-
(2009)
Mol Cell
, vol.35
, Issue.3
, pp. 265-279
-
-
Hughes, M.A.1
Harper, N.2
Butterworth, M.3
Cain, K.4
Cohen, G.M.5
MacFarlane, M.6
-
31
-
-
34147178164
-
Role of proteolysis in caspase-8 activation and stabilization
-
Pop C., Fitzgerald P., Green D.R., Salvesen G.S. Role of proteolysis in caspase-8 activation and stabilization. Biochemistry 2007, 46(14):4398-4407.
-
(2007)
Biochemistry
, vol.46
, Issue.14
, pp. 4398-4407
-
-
Pop, C.1
Fitzgerald, P.2
Green, D.R.3
Salvesen, G.S.4
-
32
-
-
33646024628
-
The apoptosome activates caspase-9 by dimerization
-
Pop C., Timmer J., Sperandio S., Salvesen G.S. The apoptosome activates caspase-9 by dimerization. Mol Cell 2006, 22(2):269-275.
-
(2006)
Mol Cell
, vol.22
, Issue.2
, pp. 269-275
-
-
Pop, C.1
Timmer, J.2
Sperandio, S.3
Salvesen, G.S.4
-
33
-
-
84896697390
-
Caspase-8 as a regulator of tumor cell motility
-
Graf R.P., Keller N., Barbero S., Stupack D. Caspase-8 as a regulator of tumor cell motility. Curr Mol Med 2014, 14(2):246-254.
-
(2014)
Curr Mol Med
, vol.14
, Issue.2
, pp. 246-254
-
-
Graf, R.P.1
Keller, N.2
Barbero, S.3
Stupack, D.4
-
34
-
-
65549085701
-
Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling
-
Jin Z., Li Y., Pitti R., Lawrence D., Pham V.C., Lill J.R. Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling. Cell 2009, 137(4):721-735.
-
(2009)
Cell
, vol.137
, Issue.4
, pp. 721-735
-
-
Jin, Z.1
Li, Y.2
Pitti, R.3
Lawrence, D.4
Pham, V.C.5
Lill, J.R.6
-
35
-
-
84871679702
-
TRAF2 sets a threshold for extrinsic apoptosis by tagging caspase-8 with a ubiquitin shutoff timer
-
Gonzalvez F., Lawrence D., Yang B., Yee S., Pitti R., Marsters S. TRAF2 sets a threshold for extrinsic apoptosis by tagging caspase-8 with a ubiquitin shutoff timer. Mol Cell 2012, 48(6):888-899.
-
(2012)
Mol Cell
, vol.48
, Issue.6
, pp. 888-899
-
-
Gonzalvez, F.1
Lawrence, D.2
Yang, B.3
Yee, S.4
Pitti, R.5
Marsters, S.6
-
36
-
-
1942534018
-
Regulation of apoptosis proteins in cancer cells by ubiquitin
-
Zhang H.G., Wang J., Yang X., Hsu H.C., Mountz J.D. Regulation of apoptosis proteins in cancer cells by ubiquitin. Oncogene 2004, 23(11):2009-2015.
-
(2004)
Oncogene
, vol.23
, Issue.11
, pp. 2009-2015
-
-
Zhang, H.G.1
Wang, J.2
Yang, X.3
Hsu, H.C.4
Mountz, J.D.5
-
37
-
-
69449095860
-
Caspases and kinases in a death grip
-
Kurokawa M., Kornbluth S. Caspases and kinases in a death grip. Cell 2009, 138(5):838-854.
-
(2009)
Cell
, vol.138
, Issue.5
, pp. 838-854
-
-
Kurokawa, M.1
Kornbluth, S.2
-
38
-
-
82755198022
-
Proliferative versus apoptotic functions of caspase-8 hetero or homo: the caspase-8 dimer controls cell fate
-
van Raam B.J., Salvesen G.S. Proliferative versus apoptotic functions of caspase-8 hetero or homo: the caspase-8 dimer controls cell fate. Biochim Biophys Acta 2012, 1824(1):113-122.
-
(2012)
Biochim Biophys Acta
, vol.1824
, Issue.1
, pp. 113-122
-
-
van Raam, B.J.1
Salvesen, G.S.2
-
39
-
-
79956323684
-
Modeling reveals that dynamic regulation of c-FLIP levels determines cell-to-cell distribution of CD95-mediated apoptosis
-
Toivonen H.T., Meinander A., Asaoka T., Westerlund M., Pettersson F., Mikhailov A. Modeling reveals that dynamic regulation of c-FLIP levels determines cell-to-cell distribution of CD95-mediated apoptosis. J Biol Chem 2011, 286(21):18375-18382.
-
(2011)
J Biol Chem
, vol.286
, Issue.21
, pp. 18375-18382
-
-
Toivonen, H.T.1
Meinander, A.2
Asaoka, T.3
Westerlund, M.4
Pettersson, F.5
Mikhailov, A.6
-
41
-
-
0030841911
-
I-FLICE: a novel inhibitor of tumor necrosis factor receptor-1- and CD-95-induced apoptosis
-
Hu S., Vincenz C., Ni J., Gentz R., Dixit V.M. I-FLICE: a novel inhibitor of tumor necrosis factor receptor-1- and CD-95-induced apoptosis. J Biol Chem 1997, 272(28):17255-17257.
-
(1997)
J Biol Chem
, vol.272
, Issue.28
, pp. 17255-17257
-
-
Hu, S.1
Vincenz, C.2
Ni, J.3
Gentz, R.4
Dixit, V.M.5
-
42
-
-
7344220967
-
Cell death attenuation by 'Usurpin': a mammalian DED-caspase homologue that precludes caspase-8 recruitment and activation by the CD-95 (Fas, APO-1) receptor complex
-
Rasper D.M., Vaillancourt J.P., Hadano S., Houtzager V.M., Seiden I., Keen S.L. Cell death attenuation by 'Usurpin': a mammalian DED-caspase homologue that precludes caspase-8 recruitment and activation by the CD-95 (Fas, APO-1) receptor complex. Cell Death Differ 1998, 5(4):271-288.
-
(1998)
Cell Death Differ
, vol.5
, Issue.4
, pp. 271-288
-
-
Rasper, D.M.1
Vaillancourt, J.P.2
Hadano, S.3
Houtzager, V.M.4
Seiden, I.5
Keen, S.L.6
-
43
-
-
0030746740
-
Casper is a FADD- and caspase-related inducer of apoptosis
-
Shu H.B., Halpin D.R., Goeddel D.V. Casper is a FADD- and caspase-related inducer of apoptosis. Immunity 1997, 6(6):751-763.
-
(1997)
Immunity
, vol.6
, Issue.6
, pp. 751-763
-
-
Shu, H.B.1
Halpin, D.R.2
Goeddel, D.V.3
-
44
-
-
0030800070
-
Inhibition of death receptors signals by cellular FLIP
-
Irmler M., Thome M., Hahne M., Schneider P., Hofmann K., Steiner V. Inhibition of death receptors signals by cellular FLIP. Nature 1997, 388:190-195.
-
(1997)
Nature
, vol.388
, pp. 190-195
-
-
Irmler, M.1
Thome, M.2
Hahne, M.3
Schneider, P.4
Hofmann, K.5
Steiner, V.6
-
45
-
-
0033556310
-
The role of c-FLIP in modulation of CD95-induced apoptosis
-
Scaffidi C., Schmitz I., Krammer P.H., Peter M.E. The role of c-FLIP in modulation of CD95-induced apoptosis. J Biol Chem 1999, 274(3):1541-1548.
-
(1999)
J Biol Chem
, vol.274
, Issue.3
, pp. 1541-1548
-
-
Scaffidi, C.1
Schmitz, I.2
Krammer, P.H.3
Peter, M.E.4
-
46
-
-
4544288868
-
Activation of caspases-8 and -10 by FLIP(L)
-
Boatright K.M., Deis C., Denault J.B., Sutherlin D.P., Salvesen G.S. Activation of caspases-8 and -10 by FLIP(L). Biochem J 2004, 382(Pt 2):651-657.
-
(2004)
Biochem J
, vol.382
, Issue.PART 2
, pp. 651-657
-
-
Boatright, K.M.1
Deis, C.2
Denault, J.B.3
Sutherlin, D.P.4
Salvesen, G.S.5
-
47
-
-
17844361968
-
Cellular FLIP (long form) regulates CD8+ T cell activation through caspase-8-dependent NF-kappa B activation
-
Dohrman A., Kataoka T., Cuenin S., Russell J.Q., Tschopp J., Budd R.C. Cellular FLIP (long form) regulates CD8+ T cell activation through caspase-8-dependent NF-kappa B activation. J Immunol 2005, 174(9):5270-5278.
-
(2005)
J Immunol
, vol.174
, Issue.9
, pp. 5270-5278
-
-
Dohrman, A.1
Kataoka, T.2
Cuenin, S.3
Russell, J.Q.4
Tschopp, J.5
Budd, R.C.6
-
48
-
-
0037160117
-
The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex
-
Micheau O., Thome M., Schneider P., Holler N., Tschopp J., Nicholson D.W. The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex. J Biol Chem 2002, 277(47):45162-45171.
-
(2002)
J Biol Chem
, vol.277
, Issue.47
, pp. 45162-45171
-
-
Micheau, O.1
Thome, M.2
Schneider, P.3
Holler, N.4
Tschopp, J.5
Nicholson, D.W.6
-
49
-
-
66249094552
-
Mechanism of procaspase-8 activation by c-FLIPL
-
Yu J.W., Jeffrey P.D., Shi Y. Mechanism of procaspase-8 activation by c-FLIPL. Proc Natl Acad Sci U S A 2009, 106(20):8169-8174.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.20
, pp. 8169-8174
-
-
Yu, J.W.1
Jeffrey, P.D.2
Shi, Y.3
-
50
-
-
78751487532
-
FLIP(L) induces caspase 8 activity in the absence of interdomain caspase 8 cleavage and alters substrate specificity
-
Pop C., Oberst A., Drag M., Van Raam B.J., Riedl S.J., Green D.R. FLIP(L) induces caspase 8 activity in the absence of interdomain caspase 8 cleavage and alters substrate specificity. Biochem J 2011, 433(3):447-457.
-
(2011)
Biochem J
, vol.433
, Issue.3
, pp. 447-457
-
-
Pop, C.1
Oberst, A.2
Drag, M.3
Van Raam, B.J.4
Riedl, S.J.5
Green, D.R.6
-
51
-
-
62349098335
-
Caspases: evolutionary aspects of their functions in vertebrates
-
Sakamaki K., Satou Y. Caspases: evolutionary aspects of their functions in vertebrates. J Fish Biol 2009, 74(4):727-753.
-
(2009)
J Fish Biol
, vol.74
, Issue.4
, pp. 727-753
-
-
Sakamaki, K.1
Satou, Y.2
-
52
-
-
46649096691
-
Identification of novel mammalian caspases reveals an important role of gene loss in shaping the human caspase repertoire
-
Eckhart L., Ballaun C., Hermann M., VandeBerg J.L., Sipos W., Uthman A. Identification of novel mammalian caspases reveals an important role of gene loss in shaping the human caspase repertoire. Mol Biol Evol 2008, 25(5):831-841.
-
(2008)
Mol Biol Evol
, vol.25
, Issue.5
, pp. 831-841
-
-
Eckhart, L.1
Ballaun, C.2
Hermann, M.3
VandeBerg, J.L.4
Sipos, W.5
Uthman, A.6
-
53
-
-
0032575714
-
Death receptors: signaling and modulation
-
Ashkenazi A., Dixit V. Death receptors: signaling and modulation. Science 1998, 281(5381):1305-1308.
-
(1998)
Science
, vol.281
, Issue.5381
, pp. 1305-1308
-
-
Ashkenazi, A.1
Dixit, V.2
-
54
-
-
0042332033
-
The fuzzy logic of the death-inducing signaling complex in lymphocytes
-
Walsh C.M., Luhrs K.A., Arechiga A.F. The fuzzy logic of the death-inducing signaling complex in lymphocytes. J Clin Immunol 2003, 23(5):333-353.
-
(2003)
J Clin Immunol
, vol.23
, Issue.5
, pp. 333-353
-
-
Walsh, C.M.1
Luhrs, K.A.2
Arechiga, A.F.3
-
55
-
-
0026568919
-
Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis
-
Watanabe-Fukunaga R., Brannan C.I., Copeland N.G., Jenkins N.A., Nagata S. Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature 1992, 356(6367):314-317.
-
(1992)
Nature
, vol.356
, Issue.6367
, pp. 314-317
-
-
Watanabe-Fukunaga, R.1
Brannan, C.I.2
Copeland, N.G.3
Jenkins, N.A.4
Nagata, S.5
-
56
-
-
0021350056
-
A new mutation, gld, that produces lymphoproliferation and autoimmunity in C3H/HeJ mice
-
Roths J.B., Murphy E.D., Eicher E.M. A new mutation, gld, that produces lymphoproliferation and autoimmunity in C3H/HeJ mice. J Exp Med 1984, 159(1):1-20.
-
(1984)
J Exp Med
, vol.159
, Issue.1
, pp. 1-20
-
-
Roths, J.B.1
Murphy, E.D.2
Eicher, E.M.3
-
57
-
-
0027145632
-
Molecular cloning and expression of the Fas ligand: a novel member of the tumor necrosis factor family
-
Suda T., Takahashi T., Golstein P., Nagata S. Molecular cloning and expression of the Fas ligand: a novel member of the tumor necrosis factor family. Cell 1993, 75(6):1169-1178.
-
(1993)
Cell
, vol.75
, Issue.6
, pp. 1169-1178
-
-
Suda, T.1
Takahashi, T.2
Golstein, P.3
Nagata, S.4
-
58
-
-
0028223847
-
Generalized lymphoproliferative disease in mice: caused by a point mutation in the Fas ligand
-
Takahashi T., Tanaka M., Brannan C., Jenkins N., Copeland N., Suda T. Generalized lymphoproliferative disease in mice: caused by a point mutation in the Fas ligand. Cell 1994, 76(6):969-976.
-
(1994)
Cell
, vol.76
, Issue.6
, pp. 969-976
-
-
Takahashi, T.1
Tanaka, M.2
Brannan, C.3
Jenkins, N.4
Copeland, N.5
Suda, T.6
-
59
-
-
0029026548
-
FADD: a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis
-
Chinnaiyan A.M., O'Rourke K., Tewari M., Dixit V.M. FADD: a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis. Cell 1995, 81(4):505-512.
-
(1995)
Cell
, vol.81
, Issue.4
, pp. 505-512
-
-
Chinnaiyan, A.M.1
O'Rourke, K.2
Tewari, M.3
Dixit, V.M.4
-
60
-
-
0028883850
-
Cytotoxicity-dependent APO-1 Fas/CD95-associated proteins form a death-inducing signaling complex DISC with the receptor
-
Kischkel F., Hellbardt S., Behrmann I., Germer M., Pawlita M., Krammer P. Cytotoxicity-dependent APO-1 Fas/CD95-associated proteins form a death-inducing signaling complex DISC with the receptor. EMBO J 1995, 14:5579-5588.
-
(1995)
EMBO J
, vol.14
, pp. 5579-5588
-
-
Kischkel, F.1
Hellbardt, S.2
Behrmann, I.3
Germer, M.4
Pawlita, M.5
Krammer, P.6
-
61
-
-
0029965280
-
FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis
-
Chinnaiyan A., Tepper C., Seldin M., O'Rourke K., Kischkel F., Hellbardt S. FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis. J Biol Chem 1996, 271(9):4961-4965.
-
(1996)
J Biol Chem
, vol.271
, Issue.9
, pp. 4961-4965
-
-
Chinnaiyan, A.1
Tepper, C.2
Seldin, M.3
O'Rourke, K.4
Kischkel, F.5
Hellbardt, S.6
-
62
-
-
0032472916
-
A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes
-
Newton K., Harris A.W., Bath M.L., Smith K.G., Strasser A. A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes. EMBO J 1998, 17(3):706-718.
-
(1998)
EMBO J
, vol.17
, Issue.3
, pp. 706-718
-
-
Newton, K.1
Harris, A.W.2
Bath, M.L.3
Smith, K.G.4
Strasser, A.5
-
63
-
-
0032055344
-
A role for FADD in T cell activation and development
-
Walsh C.M., Wen B.G., Chinnaiyan A.M., O'Rourke K., Dixit V.M., Hedrick S.M. A role for FADD in T cell activation and development. Immunity 1998, 8(4):439-449.
-
(1998)
Immunity
, vol.8
, Issue.4
, pp. 439-449
-
-
Walsh, C.M.1
Wen, B.G.2
Chinnaiyan, A.M.3
O'Rourke, K.4
Dixit, V.M.5
Hedrick, S.M.6
-
64
-
-
0032546387
-
Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1
-
Zhang J., Cado D., Chen A., Kabra N.H., Winoto A. Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1. Nature 1998, 392(6673):296-300.
-
(1998)
Nature
, vol.392
, Issue.6673
, pp. 296-300
-
-
Zhang, J.1
Cado, D.2
Chen, A.3
Kabra, N.H.4
Winoto, A.5
-
65
-
-
0029905073
-
Molecular ordering of the Fas-apoptotic pathway: the Fas/APO-1 protease Mch5 is a CrmA-inhibitable protease that activates multiple Ced-3/ICE-like cysteine proteases
-
Srinivasula S.M., Ahmad M., Fernandes-Alnemri T., Litwack G., Alnemri E.S. Molecular ordering of the Fas-apoptotic pathway: the Fas/APO-1 protease Mch5 is a CrmA-inhibitable protease that activates multiple Ced-3/ICE-like cysteine proteases. Proc Natl Acad Sci U S A 1996, 93(25):14486-14491.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, Issue.25
, pp. 14486-14491
-
-
Srinivasula, S.M.1
Ahmad, M.2
Fernandes-Alnemri, T.3
Litwack, G.4
Alnemri, E.S.5
-
66
-
-
0037380628
-
Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity
-
Salmena L., Lemmers B., Hakem A., Matysiak-Zablocki E., Murakami K., Au P.Y. Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity. Genes Dev 2003, 17(7):883-895.
-
(2003)
Genes Dev
, vol.17
, Issue.7
, pp. 883-895
-
-
Salmena, L.1
Lemmers, B.2
Hakem, A.3
Matysiak-Zablocki, E.4
Murakami, K.5
Au, P.Y.6
-
67
-
-
7144263731
-
FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis
-
Yeh W.C., Pompa J.L., McCurrach M.E., Shu H.B., Elia A.J., Shahinian A. FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis. Science 1998, 279(5358):1954-1958.
-
(1998)
Science
, vol.279
, Issue.5358
, pp. 1954-1958
-
-
Yeh, W.C.1
Pompa, J.L.2
McCurrach, M.E.3
Shu, H.B.4
Elia, A.J.5
Shahinian, A.6
-
68
-
-
0033662341
-
Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development
-
Yeh W.C., Itie A., Elia A.J., Ng M., Shu H.B., Wakeham A. Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development. Immunity 2000, 12(6):633-642.
-
(2000)
Immunity
, vol.12
, Issue.6
, pp. 633-642
-
-
Yeh, W.C.1
Itie, A.2
Elia, A.J.3
Ng, M.4
Shu, H.B.5
Wakeham, A.6
-
69
-
-
23744456144
-
An essential role for c-FLIP in the efficient development of mature T lymphocytes
-
Zhang N., He Y.W. An essential role for c-FLIP in the efficient development of mature T lymphocytes. J Exp Med 2005, 202(3):395-404.
-
(2005)
J Exp Med
, vol.202
, Issue.3
, pp. 395-404
-
-
Zhang, N.1
He, Y.W.2
-
70
-
-
23744487497
-
Cellular FLICE-inhibitory protein is required for T cell survival and cycling
-
Chau H., Wong V., Chen N.J., Huang H.L., Lin W.J., Mirtsos C. Cellular FLICE-inhibitory protein is required for T cell survival and cycling. J Exp Med 2005, 202(3):405-413.
-
(2005)
J Exp Med
, vol.202
, Issue.3
, pp. 405-413
-
-
Chau, H.1
Wong, V.2
Chen, N.J.3
Huang, H.L.4
Lin, W.J.5
Mirtsos, C.6
-
71
-
-
23844548539
-
Conditional Fas-associated death domain protein (FADD): GFP knockout mice reveal FADD is dispensable in thymic development but essential in peripheral T cell homeostasis
-
Zhang Y., Rosenberg S., Wang H., Imtiyaz H.Z., Hou Y.J., Zhang J. Conditional Fas-associated death domain protein (FADD): GFP knockout mice reveal FADD is dispensable in thymic development but essential in peripheral T cell homeostasis. J Immunol 2005, 175(5):3033-3044.
-
(2005)
J Immunol
, vol.175
, Issue.5
, pp. 3033-3044
-
-
Zhang, Y.1
Rosenberg, S.2
Wang, H.3
Imtiyaz, H.Z.4
Hou, Y.J.5
Zhang, J.6
-
72
-
-
0038205938
-
The requirements for Fas-associated death domain signaling in mature T cell activation and survival
-
Beisner D.R., Chu I.H., Arechiga A.F., Hedrick S.M., Walsh C.M. The requirements for Fas-associated death domain signaling in mature T cell activation and survival. J Immunol 2003, 171(1):247-256.
-
(2003)
J Immunol
, vol.171
, Issue.1
, pp. 247-256
-
-
Beisner, D.R.1
Chu, I.H.2
Arechiga, A.F.3
Hedrick, S.M.4
Walsh, C.M.5
-
73
-
-
33646879040
-
The Fas-associated death domain protein is required in apoptosis and TLR-induced proliferative responses in B cells
-
Imtiyaz H.Z., Rosenberg S., Zhang Y., Rahman Z.S., Hou Y.J., Manser T. The Fas-associated death domain protein is required in apoptosis and TLR-induced proliferative responses in B cells. J Immunol 2006, 176(11):6852-6861.
-
(2006)
J Immunol
, vol.176
, Issue.11
, pp. 6852-6861
-
-
Imtiyaz, H.Z.1
Rosenberg, S.2
Zhang, Y.3
Rahman, Z.S.4
Hou, Y.J.5
Manser, T.6
-
74
-
-
29144492116
-
Cutting edge: FADD is not required for antigen receptor-mediated NF-{kappa}B activation
-
Arechiga A.F., Bell B.D., Solomon J.C., Chu I.H., Dubois C.L., Hall B.E. Cutting edge: FADD is not required for antigen receptor-mediated NF-{kappa}B activation. J Immunol 2005, 175(12):7800-7804.
-
(2005)
J Immunol
, vol.175
, Issue.12
, pp. 7800-7804
-
-
Arechiga, A.F.1
Bell, B.D.2
Solomon, J.C.3
Chu, I.H.4
Dubois, C.L.5
Hall, B.E.6
-
75
-
-
24744459035
-
Cutting edge: innate immunity conferred by B cells is regulated by caspase-8
-
Beisner D.R., Ch'en I.L., Kolla R.V., Hoffmann A., Hedrick S.M. Cutting edge: innate immunity conferred by B cells is regulated by caspase-8. J Immunol 2005, 175(6):3469-3473.
-
(2005)
J Immunol
, vol.175
, Issue.6
, pp. 3469-3473
-
-
Beisner, D.R.1
Ch'en, I.L.2
Kolla, R.V.3
Hoffmann, A.4
Hedrick, S.M.5
-
76
-
-
54049130409
-
C-FLIP protects mature T lymphocytes from TCR-mediated killing
-
Zhang N., Hopkins K., He Y.W. c-FLIP protects mature T lymphocytes from TCR-mediated killing. J Immunol 2008, 181(8):5368-5373.
-
(2008)
J Immunol
, vol.181
, Issue.8
, pp. 5368-5373
-
-
Zhang, N.1
Hopkins, K.2
He, Y.W.3
-
77
-
-
45949102790
-
The long isoform of cellular FLIP is essential for T lymphocyte proliferation through an NF-kappaB-independent pathway
-
Zhang N., Hopkins K., He Y.W. The long isoform of cellular FLIP is essential for T lymphocyte proliferation through an NF-kappaB-independent pathway. J Immunol 2008, 180(8):5506-5511.
-
(2008)
J Immunol
, vol.180
, Issue.8
, pp. 5506-5511
-
-
Zhang, N.1
Hopkins, K.2
He, Y.W.3
-
78
-
-
59849129456
-
A role for cFLIP in B cell proliferation and stress MAPK regulation
-
Zhang H., Rosenberg S., Coffey F.J., He Y.W., Manser T., Hardy R.R. A role for cFLIP in B cell proliferation and stress MAPK regulation. J Immunol 2009, 182(1):207-215.
-
(2009)
J Immunol
, vol.182
, Issue.1
, pp. 207-215
-
-
Zhang, H.1
Rosenberg, S.2
Coffey, F.J.3
He, Y.W.4
Manser, T.5
Hardy, R.R.6
-
79
-
-
77954481301
-
Expression of cellular FLIP by B cells is required for their participation in an immune response
-
Coffey F., Manser T. Expression of cellular FLIP by B cells is required for their participation in an immune response. J Immunol 2010, 184(9):4871-4879.
-
(2010)
J Immunol
, vol.184
, Issue.9
, pp. 4871-4879
-
-
Coffey, F.1
Manser, T.2
-
80
-
-
84865296205
-
Programmed necrosis and autophagy in immune function
-
Lu J.V., Walsh C.M. Programmed necrosis and autophagy in immune function. Immunol Rev 2012, 249(1):205-217.
-
(2012)
Immunol Rev
, vol.249
, Issue.1
, pp. 205-217
-
-
Lu, J.V.1
Walsh, C.M.2
-
81
-
-
0033386808
-
Caspase activation is required for T cell proliferation
-
Kennedy N.J., Kataoka T., Tschopp J., Budd R.C. Caspase activation is required for T cell proliferation. J Exp Med 1999, 190(12):1891-1896.
-
(1999)
J Exp Med
, vol.190
, Issue.12
, pp. 1891-1896
-
-
Kennedy, N.J.1
Kataoka, T.2
Tschopp, J.3
Budd, R.C.4
-
82
-
-
0033378016
-
Early activation of caspases during T lymphocyte stimulation results in selective substrate cleavage in nonapoptotic cells
-
Alam A., Cohen L.Y., Aouad S., Sékaly R.-P. Early activation of caspases during T lymphocyte stimulation results in selective substrate cleavage in nonapoptotic cells. J Exp Med 1999, 190(12):1879-1890.
-
(1999)
J Exp Med
, vol.190
, Issue.12
, pp. 1879-1890
-
-
Alam, A.1
Cohen, L.Y.2
Aouad, S.3
Sékaly, R.-P.4
-
83
-
-
78650178173
-
Enzymatically active single chain caspase-8 maintains T-cell survival during clonal expansion
-
Leverrier S., Salvesen G.S., Walsh C.M. Enzymatically active single chain caspase-8 maintains T-cell survival during clonal expansion. Cell Death Differ 2011, 18(1):90-98.
-
(2011)
Cell Death Differ
, vol.18
, Issue.1
, pp. 90-98
-
-
Leverrier, S.1
Salvesen, G.S.2
Walsh, C.M.3
-
84
-
-
0033613143
-
Caspase activation: the induced-proximity model
-
Salvesen G.S., Dixit V.M. Caspase activation: the induced-proximity model. Proc Natl Acad Sci U S A 1999, 96(20):10964-10967.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, Issue.20
, pp. 10964-10967
-
-
Salvesen, G.S.1
Dixit, V.M.2
-
85
-
-
52149095957
-
Mutation of a self-processing site in caspase-8 compromises its apoptotic but not its nonapoptotic functions in bacterial artificial chromosome-transgenic mice
-
Kang T.B., Oh G.S., Scandella E., Bolinger B., Ludewig B., Kovalenko A. Mutation of a self-processing site in caspase-8 compromises its apoptotic but not its nonapoptotic functions in bacterial artificial chromosome-transgenic mice. J Immunol 2008, 181(4):2522-2532.
-
(2008)
J Immunol
, vol.181
, Issue.4
, pp. 2522-2532
-
-
Kang, T.B.1
Oh, G.S.2
Scandella, E.3
Bolinger, B.4
Ludewig, B.5
Kovalenko, A.6
-
86
-
-
3543125877
-
Modifications and intracellular trafficking of FADD/MORT1 and caspase-8 after stimulation of T lymphocytes
-
O'Reilly L.A., Divisekera U., Newton K., Scalzo K., Kataoka T., Puthalakath H. Modifications and intracellular trafficking of FADD/MORT1 and caspase-8 after stimulation of T lymphocytes. Cell Death Differ 2004, 11(7):724-736.
-
(2004)
Cell Death Differ
, vol.11
, Issue.7
, pp. 724-736
-
-
O'Reilly, L.A.1
Divisekera, U.2
Newton, K.3
Scalzo, K.4
Kataoka, T.5
Puthalakath, H.6
-
87
-
-
0034537290
-
Autophagy as a regulated pathway of cellular degradation
-
Klionsky D.J., Emr S.D. Autophagy as a regulated pathway of cellular degradation. Science 2000, 290(5497):1717-1721.
-
(2000)
Science
, vol.290
, Issue.5497
, pp. 1717-1721
-
-
Klionsky, D.J.1
Emr, S.D.2
-
88
-
-
75649112322
-
Autophagy and lymphocyte homeostasis
-
Pua H.H., He Y.W. Autophagy and lymphocyte homeostasis. Curr Top Microbiol Immunol 2009, 335:85-105.
-
(2009)
Curr Top Microbiol Immunol
, vol.335
, pp. 85-105
-
-
Pua, H.H.1
He, Y.W.2
-
89
-
-
20344406240
-
Autophagy in metazoans: cell survival in the land of plenty
-
Lum J.J., DeBerardinis R.J., Thompson C.B. Autophagy in metazoans: cell survival in the land of plenty. Nat Rev Mol Cell Biol 2005, 6(6):439-448.
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, Issue.6
, pp. 439-448
-
-
Lum, J.J.1
DeBerardinis, R.J.2
Thompson, C.B.3
-
90
-
-
7744235672
-
Death by design: apoptosis, necrosis and autophagy
-
Edinger A.L., Thompson C.B. Death by design: apoptosis, necrosis and autophagy. Curr Opin Cell Biol 2004, 16(6):663-669.
-
(2004)
Curr Opin Cell Biol
, vol.16
, Issue.6
, pp. 663-669
-
-
Edinger, A.L.1
Thompson, C.B.2
-
91
-
-
84255210700
-
Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012
-
Galluzzi L., Vitale I., Abrams J.M., Alnemri E.S., Baehrecke E.H., Blagosklonny M.V. Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012. Cell Death Differ 2012, 19(1):107-120.
-
(2012)
Cell Death Differ
, vol.19
, Issue.1
, pp. 107-120
-
-
Galluzzi, L.1
Vitale, I.2
Abrams, J.M.3
Alnemri, E.S.4
Baehrecke, E.H.5
Blagosklonny, M.V.6
-
92
-
-
13944273009
-
Autophagy and caspases: a new cell death program
-
Yu L., Lenardo M.J., Baehrecke E.H. Autophagy and caspases: a new cell death program. Cell Cycle 2004, 3(9):1124-1126.
-
(2004)
Cell Cycle
, vol.3
, Issue.9
, pp. 1124-1126
-
-
Yu, L.1
Lenardo, M.J.2
Baehrecke, E.H.3
-
93
-
-
25144457455
-
Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
-
Pattingre S., Tassa A., Qu X., Garuti R., Liang X.H., Mizushima N. Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy. Cell 2005, 122(6):927-939.
-
(2005)
Cell
, vol.122
, Issue.6
, pp. 927-939
-
-
Pattingre, S.1
Tassa, A.2
Qu, X.3
Garuti, R.4
Liang, X.H.5
Mizushima, N.6
-
94
-
-
2642553881
-
Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8
-
Yu L., Alva A., Su H., Dutt P., Freundt E., Welsh S. Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8. Science 2004, 304(5676):1500-1502.
-
(2004)
Science
, vol.304
, Issue.5676
, pp. 1500-1502
-
-
Yu, L.1
Alva, A.2
Su, H.3
Dutt, P.4
Freundt, E.5
Welsh, S.6
-
95
-
-
20144381544
-
Essential roles of Atg5 and FADD in autophagic cell death: dissection of autophagic cell death into vacuole formation and cell death
-
Pyo J.O., Jang M.H., Kwon Y.K., Lee H.J., Jun J.I., Woo H.N. Essential roles of Atg5 and FADD in autophagic cell death: dissection of autophagic cell death into vacuole formation and cell death. J Biol Chem 2005, 280(21):20722-20729.
-
(2005)
J Biol Chem
, vol.280
, Issue.21
, pp. 20722-20729
-
-
Pyo, J.O.1
Jang, M.H.2
Kwon, Y.K.3
Lee, H.J.4
Jun, J.I.5
Woo, H.N.6
-
96
-
-
70449529788
-
FLIP-mediated autophagy regulation in cell death control
-
Lee J.S., Li Q., Lee J.Y., Lee S.H., Jeong J.H., Lee H.R. FLIP-mediated autophagy regulation in cell death control. Nat Cell Biol 2009, 11(11):1355-1362.
-
(2009)
Nat Cell Biol
, vol.11
, Issue.11
, pp. 1355-1362
-
-
Lee, J.S.1
Li, Q.2
Lee, J.Y.3
Lee, S.H.4
Jeong, J.H.5
Lee, H.R.6
-
97
-
-
77953783023
-
The complex interplay between autophagy, apoptosis, and necrotic signals promotes T-cell homeostasis
-
Walsh C.M., Edinger A.L. The complex interplay between autophagy, apoptosis, and necrotic signals promotes T-cell homeostasis. Immunol Rev 2010, 236:95-109.
-
(2010)
Immunol Rev
, vol.236
, pp. 95-109
-
-
Walsh, C.M.1
Edinger, A.L.2
-
98
-
-
55949083821
-
FADD and caspase-8 control the outcome of autophagic signaling in proliferating T cells
-
Bell B.D., Leverrier S., Weist B.M., Newton R.H., Arechiga A.F., Luhrs K.A. FADD and caspase-8 control the outcome of autophagic signaling in proliferating T cells. Proc Natl Acad Sci U S A 2008, 105(43):16677-16682.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.43
, pp. 16677-16682
-
-
Bell, B.D.1
Leverrier, S.2
Weist, B.M.3
Newton, R.H.4
Arechiga, A.F.5
Luhrs, K.A.6
-
99
-
-
56249132503
-
Antigen-mediated T cell expansion regulated by parallel pathways of death
-
Ch'en I.L., Beisner D.R., Degterev A., Lynch C., Yuan J., Hoffmann A. Antigen-mediated T cell expansion regulated by parallel pathways of death. Proc Natl Acad Sci U S A 2008, 105(45):17463-17468.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.45
, pp. 17463-17468
-
-
Ch'en, I.L.1
Beisner, D.R.2
Degterev, A.3
Lynch, C.4
Yuan, J.5
Hoffmann, A.6
-
100
-
-
5944233768
-
Fas triggers an alternative: caspase-8-independent cell death pathway using the kinase RIP as effector molecule
-
Holler N., Zaru R., Micheau O., Thome M., Attinger A., Valitutti S. Fas triggers an alternative: caspase-8-independent cell death pathway using the kinase RIP as effector molecule. Nat Immunol 2000, 1(6):489-495.
-
(2000)
Nat Immunol
, vol.1
, Issue.6
, pp. 489-495
-
-
Holler, N.1
Zaru, R.2
Micheau, O.3
Thome, M.4
Attinger, A.5
Valitutti, S.6
-
101
-
-
33644840693
-
Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury
-
Degterev A., Huang Z., Boyce M., Li Y., Jagtap P., Mizushima N. Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury. Nat Chem Biol 2005, 1(2):112-119.
-
(2005)
Nat Chem Biol
, vol.1
, Issue.2
, pp. 112-119
-
-
Degterev, A.1
Huang, Z.2
Boyce, M.3
Li, Y.4
Jagtap, P.5
Mizushima, N.6
-
102
-
-
0032583164
-
Caspase-independent cell killing by Fas-associated protein with death domain
-
Kawahara A., Ohsawa Y., Matsumura H., Uchiyama Y., Nagata S. Caspase-independent cell killing by Fas-associated protein with death domain. J Cell Biol 1998, 143(5):1353-1360.
-
(1998)
J Cell Biol
, vol.143
, Issue.5
, pp. 1353-1360
-
-
Kawahara, A.1
Ohsawa, Y.2
Matsumura, H.3
Uchiyama, Y.4
Nagata, S.5
-
103
-
-
57649181391
-
Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway
-
Hitomi J., Christofferson D.E., Ng A., Yao J., Degterev A., Xavier R.J. Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway. Cell 2008, 135(7):1311-1323.
-
(2008)
Cell
, vol.135
, Issue.7
, pp. 1311-1323
-
-
Hitomi, J.1
Christofferson, D.E.2
Ng, A.3
Yao, J.4
Degterev, A.5
Xavier, R.J.6
-
104
-
-
42449123761
-
Expansion and evolution of cell death programmes
-
Degterev A., Yuan J. Expansion and evolution of cell death programmes. Nat Rev Mol Cell Biol 2008, 9(5):378-390.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, Issue.5
, pp. 378-390
-
-
Degterev, A.1
Yuan, J.2
-
105
-
-
77955609495
-
Fas-associated death domain (FADD) is a negative regulator of T-cell receptor-mediated necroptosis
-
Osborn S.L., Diehl G., Han S.J., Xue L., Kurd N., Hsieh K. Fas-associated death domain (FADD) is a negative regulator of T-cell receptor-mediated necroptosis. Proc Natl Acad Sci U S A 2010, 107(29):13034-13039.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, Issue.29
, pp. 13034-13039
-
-
Osborn, S.L.1
Diehl, G.2
Han, S.J.3
Xue, L.4
Kurd, N.5
Hsieh, K.6
-
106
-
-
34548437549
-
Cleavage of RIP3 inactivates its caspase-independent apoptosis pathway by removal of kinase domain
-
Feng S., Yang Y., Mei Y., Ma L., Zhu D.E., Hoti N. Cleavage of RIP3 inactivates its caspase-independent apoptosis pathway by removal of kinase domain. Cell Signal 2007, 19(10):2056-2067.
-
(2007)
Cell Signal
, vol.19
, Issue.10
, pp. 2056-2067
-
-
Feng, S.1
Yang, Y.2
Mei, Y.3
Ma, L.4
Zhu, D.E.5
Hoti, N.6
-
107
-
-
67650812332
-
RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis
-
Zhang D.W., Shao J., Lin J., Zhang N., Lu B.J., Lin S.C. RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis. Science 2009, 325(5938):332-336.
-
(2009)
Science
, vol.325
, Issue.5938
, pp. 332-336
-
-
Zhang, D.W.1
Shao, J.2
Lin, J.3
Zhang, N.4
Lu, B.J.5
Lin, S.C.6
-
108
-
-
66749183275
-
Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha
-
He S.W.L., Miao L., Wang T., Du F., Zhao L., Wang X. Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha. Cell 2009, 137(6):1100-1111.
-
(2009)
Cell
, vol.137
, Issue.6
, pp. 1100-1111
-
-
He, S.W.L.1
Miao, L.2
Wang, T.3
Du, F.4
Zhao, L.5
Wang, X.6
-
109
-
-
66449133280
-
Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation
-
Cho Y.S., Challa S., Moquin D., Genga R., Ray T.D., Guildford M. Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation. Cell 2009, 137(6):1112-1123.
-
(2009)
Cell
, vol.137
, Issue.6
, pp. 1112-1123
-
-
Cho, Y.S.1
Challa, S.2
Moquin, D.3
Genga, R.4
Ray, T.D.5
Guildford, M.6
-
110
-
-
67650638892
-
RIP kinases at the crossroads of cell death and survival
-
Declercq W., Vanden Berghe T., Vandenabeele P. RIP kinases at the crossroads of cell death and survival. Cell 2009, 138(2):229-232.
-
(2009)
Cell
, vol.138
, Issue.2
, pp. 229-232
-
-
Declercq, W.1
Vanden Berghe, T.2
Vandenabeele, P.3
-
111
-
-
77953672526
-
The role of the kinases RIP1 and RIP3 in TNF-induced necrosis
-
Vandenabeele P., Declercq W., Van Herreweghe F., Vanden Berghe T. The role of the kinases RIP1 and RIP3 in TNF-induced necrosis. Sci Signal 2010, 3(115):re4.
-
(2010)
Sci Signal
, vol.3
, Issue.115
-
-
Vandenabeele, P.1
Declercq, W.2
Van Herreweghe, F.3
Vanden Berghe, T.4
-
112
-
-
79952811804
-
RIP3 mediates the embryonic lethality of caspase-8-deficient mice
-
Kaiser W.J., Upton J.W., Long A.B., Livingston-Rosanoff D., Daley-Bauer L.P., Hakem R. RIP3 mediates the embryonic lethality of caspase-8-deficient mice. Nature 2011, 471(7338):368-372.
-
(2011)
Nature
, vol.471
, Issue.7338
, pp. 368-372
-
-
Kaiser, W.J.1
Upton, J.W.2
Long, A.B.3
Livingston-Rosanoff, D.4
Daley-Bauer, L.P.5
Hakem, R.6
-
113
-
-
79952780505
-
Functional complementation between FADD and RIP1 in embryos and lymphocytes
-
Zhang H., Zhou X., McQuade T., Li J., Chan F.K., Zhang J. Functional complementation between FADD and RIP1 in embryos and lymphocytes. Nature 2011, 471(7338):373-376.
-
(2011)
Nature
, vol.471
, Issue.7338
, pp. 373-376
-
-
Zhang, H.1
Zhou, X.2
McQuade, T.3
Li, J.4
Chan, F.K.5
Zhang, J.6
-
114
-
-
79952810024
-
Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis
-
Oberst A., Dillon C.P., Weinlich R., McCormick L.L., Fitzgerald P., Pop C. Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis. Nature 2011, 471(7338):363-367.
-
(2011)
Nature
, vol.471
, Issue.7338
, pp. 363-367
-
-
Oberst, A.1
Dillon, C.P.2
Weinlich, R.3
McCormick, L.L.4
Fitzgerald, P.5
Pop, C.6
-
115
-
-
80053087284
-
Complementary roles of Fas-associated death domain (FADD) and receptor interacting protein kinase-3 (RIPK3) in T-cell homeostasis and antiviral immunity
-
Lu J.V., Weist B.M., van Raam B.J., Marro B.S., Nguyen L.V., Srinivas P. Complementary roles of Fas-associated death domain (FADD) and receptor interacting protein kinase-3 (RIPK3) in T-cell homeostasis and antiviral immunity. Proc Natl Acad Sci U S A 2011, 108(37):15312-15317.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, Issue.37
, pp. 15312-15317
-
-
Lu, J.V.1
Weist, B.M.2
van Raam, B.J.3
Marro, B.S.4
Nguyen, L.V.5
Srinivas, P.6
-
116
-
-
79955484750
-
Mechanisms of necroptosis in T cells
-
Ch'en I.L., Tsau J.S., Molkentin J.D., Komatsu M., Hedrick S.M. Mechanisms of necroptosis in T cells. J Exp Med 2011, 208(4):633-641.
-
(2011)
J Exp Med
, vol.208
, Issue.4
, pp. 633-641
-
-
Ch'en, I.L.1
Tsau, J.S.2
Molkentin, J.D.3
Komatsu, M.4
Hedrick, S.M.5
-
117
-
-
0033214236
-
Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis
-
Lin Y., Devin A., Rodriguez Y., Liu Z.-G. Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis. Genes Dev 1999, 13(19):2514-2526.
-
(1999)
Genes Dev
, vol.13
, Issue.19
, pp. 2514-2526
-
-
Lin, Y.1
Devin, A.2
Rodriguez, Y.3
Liu, Z.-G.4
-
118
-
-
0032033132
-
The death domain kinase RIP mediates the TNF-induced NF-kappaB signal
-
Kelliher M.A., Grimm S., Ishida Y., Kuo F., Stanger B.Z., Leder P. The death domain kinase RIP mediates the TNF-induced NF-kappaB signal. Immunity 1998, 8(3):297-303.
-
(1998)
Immunity
, vol.8
, Issue.3
, pp. 297-303
-
-
Kelliher, M.A.1
Grimm, S.2
Ishida, Y.3
Kuo, F.4
Stanger, B.Z.5
Leder, P.6
-
119
-
-
0029858348
-
RIP mediates tumor necrosis factor receptor 1 activation of NF-kappaB but not Fas/APO-1-initiated apoptosis
-
Ting A.T., Pimentel-Muinos F.X., Seed B. RIP mediates tumor necrosis factor receptor 1 activation of NF-kappaB but not Fas/APO-1-initiated apoptosis. EMBO J 1996, 15(22):6189-6196.
-
(1996)
EMBO J
, vol.15
, Issue.22
, pp. 6189-6196
-
-
Ting, A.T.1
Pimentel-Muinos, F.X.2
Seed, B.3
-
120
-
-
84871030776
-
Intrinsic cleavage of receptor-interacting protein kinase-1 by caspase-6
-
van Raam B.J., Ehrnhoefer D.E., Hayden M.R., Salvesen G.S. Intrinsic cleavage of receptor-interacting protein kinase-1 by caspase-6. Cell Death Differ 2013, 20(1):86-96.
-
(2013)
Cell Death Differ
, vol.20
, Issue.1
, pp. 86-96
-
-
van Raam, B.J.1
Ehrnhoefer, D.E.2
Hayden, M.R.3
Salvesen, G.S.4
-
121
-
-
84856160569
-
Caspase 8 inhibits programmed necrosis by processing CYLD
-
O'Donnell M.A., Perez-Jimenez E., Oberst A., Ng A., Massoumi R., Xavier R. Caspase 8 inhibits programmed necrosis by processing CYLD. Nat Cell Biol 2011, 13(12):1437-1442.
-
(2011)
Nat Cell Biol
, vol.13
, Issue.12
, pp. 1437-1442
-
-
O'Donnell, M.A.1
Perez-Jimenez, E.2
Oberst, A.3
Ng, A.4
Massoumi, R.5
Xavier, R.6
-
122
-
-
84861712290
-
Survival function of the FADD-CASPASE-8-cFLIP(L) complex
-
Dillon C.P., Oberst A., Weinlich R., Janke L.J., Kang T.B., Ben-Moshe T. Survival function of the FADD-CASPASE-8-cFLIP(L) complex. Cell Rep 2012, 1(5):401-407.
-
(2012)
Cell Rep
, vol.1
, Issue.5
, pp. 401-407
-
-
Dillon, C.P.1
Oberst, A.2
Weinlich, R.3
Janke, L.J.4
Kang, T.B.5
Ben-Moshe, T.6
-
123
-
-
61649098378
-
Coordinate regulation of autophagy and apoptosis in T cells by death effectors: FADD or foundation
-
Bell B.D., Walsh C.M. Coordinate regulation of autophagy and apoptosis in T cells by death effectors: FADD or foundation. Autophagy 2009, 5(2):238-240.
-
(2009)
Autophagy
, vol.5
, Issue.2
, pp. 238-240
-
-
Bell, B.D.1
Walsh, C.M.2
|