Specificity and catalytic mechanism in family 5 uracil DNA glycosylase

Journal of Biological Chemistry

Volumn 289, Issue 26, 2014, Pages 18413-18426

  Xia, Bo ^a   Liu, Yinling ^a   Li, Wei ^a   Brice, Allyn R ^a   Dominy, Brian N ^a   Cao, Weiguo ^a  

^a CLEMSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC COMPOUNDS; HYDROGEN BONDS; MOLECULAR DYNAMICS;

CATALYTIC MECHANISMS; CATALYTIC RESIDUE; FUNCTIONAL DIVERSITY; GENETIC ANALYSIS; MUTATIONAL ANALYSIS; POTENTIALS OF MEAN FORCES; THERMUS THERMOPHILUS HB8; URACIL-DNA GLYCOSYLASE;

DNA;

DEOXYURIDINE TRIPHOSPHATE PYROPHOSPHATASE; DNA; DNA GLYCOSYLTRANSFERASE; DOUBLE STRANDED DNA; HYPOXANTHINE DNA GLYCOSYLTRANSFERASE; SINGLE STRANDED DNA; UNCLASSIFIED DRUG; URACIL; URACIL DNA GLYCOSIDASE; XANTHINE DNA GLYCOSYLASE;

ARTICLE; BACTERIAL CELL; BACTERIAL GENE; BASE PAIRING; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; CORRELATION ANALYSIS; DISSOCIATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME STABILITY; ESCHERICHIA COLI; GENETIC ANALYSIS; HYDROGEN BOND; IN VITRO STUDY; MOLECULAR DYNAMICS; MOLECULAR MODEL; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; UNG DUT XTH GENE;

DEAMINATION; DNA DAMAGE; DNA GLYCOSYLASE; DNA REPAIR; HYPOXANTHINE; MOLECULAR MODELING; MUTAGENESIS; NUCLEIC ACID ENZYMOLOGY; URACIL; XANTHINE;

AMINO ACID SEQUENCE; CATALYSIS; DNA REPAIR; HYPOXANTHINE; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; SEQUENCE ALIGNMENT; SUBSTRATE SPECIFICITY; THERMUS THERMOPHILUS; URACIL; URACIL-DNA GLYCOSIDASE; XANTHINE;

EID: 84903517886     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.567354     Document Type: Article

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