A novel uracil-DNA glycosylase with broad substrate specificity and an unusual active site

EMBO Journal

Volumn 21, Issue 12, 2002, Pages 3182-3191

  Sartori, Alessandro A ^a   Fitz Gibbon, Sorel ^a   Yang, Hanjing ^a   Miller, Jeffrey H ^a   Jiricny, Josef ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Archaea; Deamination; DNA repair thermophiles; Uracil DNA glycosylase

Indexed keywords

URACIL DNA GLYCOSYLTRANSFERASE;

AMINO ACID SEQUENCE; ARTICLE; CATALYSIS; CRENARCHAEOTA; DEAMINATION; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME SPECIFICITY; HIGH TEMPERATURE; MUTAGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN EXPRESSION;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ARCHAEAL PROTEINS; BINDING SITES; DNA GLYCOSYLASES; DNA REPAIR; ESCHERICHIA COLI; HUMANS; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; MUTAGENESIS, SITE-DIRECTED; N-GLYCOSYL HYDROLASES; OPEN READING FRAMES; SEQUENCE ALIGNMENT; SUBSTRATE SPECIFICITY; THERMOPROTEACEAE; URACIL-DNA GLYCOSIDASE;

ACTINOBACTERIA (CLASS); ARCHAEA; CRENARCHAEOTA; PYROBACULUM; PYROBACULUM AEROPHILUM; UNCULTURED ACTINOMYCETE;

EID: 0037124349     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdf309     Document Type: Article

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